{ "graphs" : [ { "id" : "http://purl.obolibrary.org/obo/pato.json", "meta" : { "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000700", "val" : "http://purl.obolibrary.org/obo/PATO_0000001" }, { "pred" : "http://purl.org/dc/elements/1.1/description", "val" : "An ontology of phenotypic qualities (properties, attributes or characteristics)." }, { "pred" : "http://purl.org/dc/elements/1.1/title", "val" : "PATO - the Phenotype And Trait Ontology" }, { "pred" : "http://purl.org/dc/terms/license", "val" : "https://creativecommons.org/licenses/by/3.0/" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#default-namespace", "val" : "quality" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBOFormatVersion", "val" : "1.2" }, { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", "val" : "2024-11-11" } ], "version" : "http://purl.obolibrary.org/obo/pato/releases/2024-11-11/pato.json" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/BFO_0000002", "type" : "CLASS" }, { "id" : "http://purl.obolibrary.org/obo/BFO_0000003", "type" : "CLASS" }, { "id" : "http://purl.obolibrary.org/obo/BFO_0000004", "type" : "CLASS" }, { "id" : "http://purl.obolibrary.org/obo/BFO_0000006", "type" : "CLASS" }, { "id" : "http://purl.obolibrary.org/obo/BFO_0000015", "type" : "CLASS" }, { "id" : "http://purl.obolibrary.org/obo/BFO_0000017", "type" : "CLASS" }, { "id" : "http://purl.obolibrary.org/obo/BFO_0000019", "type" : "CLASS" }, { "id" : "http://purl.obolibrary.org/obo/BFO_0000020", "type" : "CLASS" }, { "id" : "http://purl.obolibrary.org/obo/BFO_0000023", "type" : "CLASS" }, { "id" : "http://purl.obolibrary.org/obo/BFO_0000027", "type" : "CLASS" }, { "id" : "http://purl.obolibrary.org/obo/BFO_0000040", "type" : "CLASS" }, { "id" : "http://purl.obolibrary.org/obo/BFO_0000141", "type" : "CLASS" }, { "id" : "http://purl.obolibrary.org/obo/CARO_0000000", "type" : "CLASS" }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_10545", "lbl" : "electron", "type" : "CLASS", "meta" : { "definition" : { "val" : "Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "electron", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasExactSynonym", "val" : "electron", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Elektron", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "beta", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "beta(-)", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "beta-particle", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "e", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "e(-)", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "e-", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "negatron", "xrefs" : [ "IUPAC" ] } ], "xrefs" : [ { "val" : "KEGG:C05359" }, { "val" : "Wikipedia:Electron" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_132153", "lbl" : "hyaluronate", "type" : "CLASS", "meta" : { "definition" : { "val" : "A carbohydrate acid derivative anion obtained by deprotonation of the carboxy groups of hyaluronic acid; major species at pH 7.3." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "hyaluronan", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "hyaluronate polyanion", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_138103", "lbl" : "inorganic acid", "type" : "CLASS", "meta" : { "definition" : { "val" : "A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "inorganic acids", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "mineral acid", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "mineral acids", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Mineral_acid" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_138675", "lbl" : "gas molecular entity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "gas molecular entities", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "gaseous molecular entities", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "gaseous molecular entity", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:https://en.wikipedia.org/wiki/Gas" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_13941", "lbl" : "carbamate", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "carbamate", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "Carbamat", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Karbamat", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "carbamate ion", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "carbamic acid, ion(1-)", "xrefs" : [ "ChemIDplus" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_15339", "lbl" : "acceptor", "type" : "CLASS", "meta" : { "definition" : { "val" : "A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Acceptor", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "A", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Akzeptor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Hydrogen-acceptor", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Oxidized donor", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "accepteur", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C00028" }, { "val" : "KEGG:C16722" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13699" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:2377" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_15355", "lbl" : "acetylcholine", "type" : "CLASS", "meta" : { "definition" : { "val" : "Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "ACETYLCHOLINE", "xrefs" : [ "PDBeChem" ] }, { "pred" : "hasExactSynonym", "val" : "Acetylcholine", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasExactSynonym", "val" : "acetylcholine", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "ACh", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "Azetylcholin", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "O-Acetylcholine", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "choline acetate", "xrefs" : [ "ChemIDplus" ] } ], "xrefs" : [ { "val" : "DrugBank:DB03128" }, { "val" : "KEGG:C01996" }, { "val" : "LINCS:LSM-5888" }, { "val" : "PDBeChem:ACH" }, { "val" : "Wikipedia:Acetylcholine" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:12686" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13715" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:22197" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:2416" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:40559" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_15366", "lbl" : "acetic acid", "type" : "CLASS", "meta" : { "definition" : { "val" : "A simple monocarboxylic acid containing two carbons." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "ACETIC ACID", "xrefs" : [ "PDBeChem" ] }, { "pred" : "hasExactSynonym", "val" : "Acetic acid", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "AcOH", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "CH3-COOH", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "CH3CO2H", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "E 260", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "E-260", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "E260", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Essigsaeure", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Ethanoic acid", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Ethylic acid", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "HOAc", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "INS No. 260", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "MeCO2H", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "MeCOOH", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Methanecarboxylic acid", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "acide acetique", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "ethoic acid", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "HMDB:HMDB0000042" }, { "val" : "KEGG:C00033" }, { "val" : "KEGG:D00010" }, { "val" : "KNApSAcK:C00001176" }, { "val" : "MetaCyc:ACET" }, { "val" : "PDBeChem:ACT" }, { "val" : "PDBeChem:ACY" }, { "val" : "PPDB:1333" }, { "val" : "Wikipedia:Acetic_acid" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:22169" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:2387" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:40486" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_15379", "lbl" : "dioxygen", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Disauerstoff", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "E 948", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "E-948", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "E948", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "O2", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "O2", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "O2", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "OXYGEN MOLECULE", "xrefs" : [ "PDBeChem" ] }, { "pred" : "hasRelatedSynonym", "val" : "Oxygen", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "[OO]", "xrefs" : [ "MolBase" ] }, { "pred" : "hasRelatedSynonym", "val" : "dioxygene", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "molecular oxygen", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "HMDB:HMDB0001377" }, { "val" : "KEGG:C00007" }, { "val" : "KEGG:D00003" }, { "val" : "MetaCyc:OXYGEN-MOLECULE" }, { "val" : "MolBase:750" }, { "val" : "PDBeChem:OXY" }, { "val" : "Wikipedia:Oxygen" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:10745" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13416" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:23833" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:25366" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:30491" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:44742" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:7860" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_15841", "lbl" : "polypeptide", "type" : "CLASS", "meta" : { "definition" : { "val" : "A peptide containing ten or more amino acid residues." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Polypeptide", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Polypeptid", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "polipeptido", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C00403" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:14860" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:8314" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_15986", "lbl" : "polynucleotide", "type" : "CLASS", "meta" : { "definition" : { "val" : "A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Polynucleotide", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "polynucleotides", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C00419" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13672" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:14859" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:8312" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_16134", "lbl" : "ammonia", "type" : "CLASS", "meta" : { "definition" : { "val" : "An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "AMMONIA", "xrefs" : [ "PDBeChem" ] }, { "pred" : "hasExactSynonym", "val" : "Ammonia", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Ammoniak", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "NH3", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "NH3", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "NH3", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "R-717", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "[NH3]", "xrefs" : [ "MolBase" ] }, { "pred" : "hasRelatedSynonym", "val" : "ammoniac", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "amoniaco", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "spirit of hartshorn", "xrefs" : [ "ChemIDplus" ] } ], "xrefs" : [ { "val" : "HMDB:HMDB0000051" }, { "val" : "KEGG:C00014" }, { "val" : "KEGG:D02916" }, { "val" : "KNApSAcK:C00007267" }, { "val" : "MetaCyc:AMMONIA" }, { "val" : "MolBase:930" }, { "val" : "PDBeChem:NH3" }, { "val" : "Wikipedia:Ammonia" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13405" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13406" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13407" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13771" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:22533" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:44269" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:44284" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:44404" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:7434" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_16189", "lbl" : "sulfate", "type" : "CLASS", "meta" : { "definition" : { "val" : "A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Sulfate", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasExactSynonym", "val" : "sulfate", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "SO4(2-)", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "SULFATE ION", "xrefs" : [ "PDBeChem" ] }, { "pred" : "hasRelatedSynonym", "val" : "Sulfate anion(2-)", "xrefs" : [ "HMDB" ] }, { "pred" : "hasRelatedSynonym", "val" : "Sulfate dianion", "xrefs" : [ "HMDB" ] }, { "pred" : "hasRelatedSynonym", "val" : "Sulfate(2-)", "xrefs" : [ "HMDB" ] }, { "pred" : "hasRelatedSynonym", "val" : "Sulfuric acid ion(2-)", "xrefs" : [ "HMDB" ] }, { "pred" : "hasRelatedSynonym", "val" : "[SO4](2-)", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "sulphate", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "sulphate ion", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "HMDB:HMDB0001448" }, { "val" : "KEGG:C00059" }, { "val" : "KEGG:D05963" }, { "val" : "MetaCyc:SULFATE" }, { "val" : "PDBeChem:SO4" }, { "val" : "Wikipedia:Sulfate" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:15135" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:45687" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:9335" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_16336", "lbl" : "hyaluronic acid", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates. A principal constituent of the extracellular matrix (ECM), it mediates the growth and metastasis of tumour cells." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Hyaluronic acid", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Hyaluronsaeure", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "[beta-D-glucopyranuronosyl-(1->3)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)]n", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "[beta-N-Acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)]n", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "acide hyaluronique", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "acido hialuronico", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "hyaluronan", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "HMDB:HMDB0010366" }, { "val" : "KEGG:C00518" }, { "val" : "KEGG:D08043" }, { "val" : "KEGG:G10505" }, { "val" : "Wikipedia:Hyaluronan" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:14412" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:24622" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:24623" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:5772" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_16541", "lbl" : "protein polypeptide chain", "type" : "CLASS", "meta" : { "definition" : { "val" : "A naturally occurring polypeptide synthesized at the ribosome." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Protein", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "a protein", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "polypeptide chain", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "protein polypeptide chains", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C00017" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:8526" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_16646", "lbl" : "carbohydrate", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Kohlenhydrat", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Kohlenhydrate", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "a carbohydrate", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "carbohidrato", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "carbohidratos", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "glucide", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "glucides", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "glucido", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "glucidos", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "hydrates de carbone", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "saccharide", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "saccharides", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "saccharidum", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Carbohydrate" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:15131" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:23008" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:9318" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_16670", "lbl" : "peptide", "type" : "CLASS", "meta" : { "definition" : { "val" : "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Peptide", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Peptid", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "peptido", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "peptidos", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C00012" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:14753" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:25906" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:7990" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_166902", "lbl" : "noradrenaline(1+)", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#2_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "noradrenaline", "xrefs" : [ "UniProt" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_167559", "lbl" : "glycan", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "glycans", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_16765", "lbl" : "tryptamine", "type" : "CLASS", "meta" : { "definition" : { "val" : "An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Tryptamine", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "1H-indole-3-ethanamine", "xrefs" : [ "NIST_Chemistry_WebBook" ] }, { "pred" : "hasRelatedSynonym", "val" : "2-(1H-INDOL-3-YL)ETHANAMINE", "xrefs" : [ "PDBeChem" ] }, { "pred" : "hasRelatedSynonym", "val" : "2-(3-indolyl)ethylamine", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "3-(2-Aminoethyl)indole", "xrefs" : [ "KEGG_COMPOUND" ] } ], "xrefs" : [ { "val" : "DrugBank:DB08653" }, { "val" : "HMDB:HMDB0000303" }, { "val" : "KEGG:C00398" }, { "val" : "KNApSAcK:C00001434" }, { "val" : "MetaCyc:TRYPTAMINE" }, { "val" : "PDBeChem:TSS" }, { "val" : "Wikipedia:Tryptamine" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:15274" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:27161" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:46157" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:9767" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_17087", "lbl" : "ketone", "type" : "CLASS", "meta" : { "definition" : { "val" : "A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Ketone", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Keton", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "R-CO-R'", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "a ketone", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "cetone", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "ketones", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C01450" }, { "val" : "Wikipedia:Ketone" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13427" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13646" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:24974" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:6127" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:8742" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_17089", "lbl" : "glycoprotein", "type" : "CLASS", "meta" : { "definition" : { "val" : "A compound in which a carbohydrate component is covalently bound to a protein component." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Glycoprotein", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Glykoprotein", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Glykoproteine", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "a glycoprotein", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "glicoproteina", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "glicoproteinas", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "glycoproteine", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "glycoproteines", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C00326" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:14349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:5481" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:5493" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_17891", "lbl" : "donor", "type" : "CLASS", "meta" : { "definition" : { "val" : "A molecular entity that can transfer (\"donate\") an electron, a pair of electrons, an atom or a group to another molecular entity." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Donor", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Donator", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "donneur", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C01351" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:14202" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:4697" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_18059", "lbl" : "lipid", "type" : "CLASS", "meta" : { "definition" : { "val" : "'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Lipid", "xrefs" : [ "KEGG_COMPOUND" ] } ], "xrefs" : [ { "val" : "KEGG:C01356" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:14517" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:25054" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:6486" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_18085", "lbl" : "glycosaminoglycan", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any polysaccharide containing a substantial proportion of aminomonosaccharide residues." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Glycosaminoglycan", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Glykosaminoglykan", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "glicosaminoglicano", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "glycosaminoglycane", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "glycosaminoglycans", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C02545" }, { "val" : "Wikipedia:Glycosaminoglycan" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:14361" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:24398" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:5495" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_18154", "lbl" : "polysaccharide", "type" : "CLASS", "meta" : { "definition" : { "val" : "A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Polysaccharide", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Glycan", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Glycane", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Glykan", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Glykane", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "glycans", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "polisacarido", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "polisacaridos", "xrefs" : [ "IUPAC" ] } ], "xrefs" : [ { "val" : "KEGG:C00420" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:14864" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:26205" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:8322" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_18282", "lbl" : "nucleobase", "type" : "CLASS", "meta" : { "definition" : { "val" : "That part of DNA or RNA that may be involved in pairing." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Base", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "nucleobases", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C00701" }, { "val" : "Wikipedia:Nucleobase" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13873" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:25598" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:2995" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_18357", "lbl" : "(R)-noradrenaline", "type" : "CLASS", "meta" : { "definition" : { "val" : "The R-enantiomer of noradrenaline." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "(-)-arterenol", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "(-)-noradrenaline", "xrefs" : [ "IUPHAR" ] }, { "pred" : "hasRelatedSynonym", "val" : "(-)-norepinephrine", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "(R)-(-)-norepinephrine", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "(R)-norepinephrine", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Arterenol", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "L-NOREPINEPHRINE", "xrefs" : [ "PDBeChem" ] }, { "pred" : "hasRelatedSynonym", "val" : "L-Noradrenaline", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Noradrenaline", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Norepinephrine", "xrefs" : [ "KEGG_COMPOUND" ] } ], "xrefs" : [ { "val" : "DrugBank:DB00368" }, { "val" : "HMDB:HMDB0000216" }, { "val" : "KEGG:C00547" }, { "val" : "KEGG:D00076" }, { "val" : "KNApSAcK:C00001424" }, { "val" : "PDBeChem:LNR" }, { "val" : "Wikipedia:Norepinephrine" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:1" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:14668" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:25592" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:258884" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:43725" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_22221", "lbl" : "acyl group", "type" : "CLASS", "meta" : { "definition" : { "val" : "An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "acyl group", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "acyl groups", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "alkanoyl group", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "groupe acyle", "xrefs" : [ "IUPAC" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_22315", "lbl" : "alkaloid", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Alkaloid", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Alkaloide", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "alcaloide", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "alcaloides", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Alkaloid" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_22506", "lbl" : "aminoglycan", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "aminoglycans", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_22563", "lbl" : "anion", "type" : "CLASS", "meta" : { "definition" : { "val" : "A monoatomic or polyatomic species having one or more elementary charges of the electron." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Anion", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasExactSynonym", "val" : "anion", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Anionen", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "aniones", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "anions", "xrefs" : [ "IUPAC" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_22695", "lbl" : "base", "type" : "CLASS", "meta" : { "definition" : { "val" : "A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Base", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasExactSynonym", "val" : "base", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Base1", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Base2", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Basen", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Nucleobase", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "bases", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C00701" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_22728", "lbl" : "benzopyrrole", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "benzopyrroles", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_228364", "lbl" : "NMR chemical shift reference compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any compound that produces a peak used to reference an NMR spectrum during data pre-processing." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "NMR chemical shift reference compounds", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "NMR chemical shift standard", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "NMR chemical shift standards", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "NMR internal standard", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "NMR internal standards", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "NMR reference standard", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "NMR reference standards", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_23004", "lbl" : "carbamoyl group", "type" : "CLASS", "meta" : { "definition" : { "val" : "The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "-C(O)NH2", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "-CONH2", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "aminocarbonyl", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "carbamyl", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "carbamyl group", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "carboxamide", "xrefs" : [ "IUPAC" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_23019", "lbl" : "carbonyl group", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "carbonyl group", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasExactSynonym", "val" : "carbonyl group", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : ">C=O", "xrefs" : [ "IUPAC" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_23357", "lbl" : "cofactor", "type" : "CLASS", "meta" : { "definition" : { "val" : "An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cofactor", "xrefs" : [ "IUPAC" ] } ], "xrefs" : [ { "val" : "Wikipedia:Cofactor_(biochemistry)" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_23367", "lbl" : "molecular entity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "entidad molecular", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "entidades moleculares", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "entite moleculaire", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "molecular entities", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "molekulare Entitaet", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_23449", "lbl" : "cyclic peptide", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Cyclopeptid", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Zyklopeptid", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "cyclic peptides", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "peptide cyclique", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "peptido ciclico", "xrefs" : [ "IUPAC" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_23888", "lbl" : "drug", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "drugs", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "medicine", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_23924", "lbl" : "enzyme inhibitor", "type" : "CLASS", "meta" : { "definition" : { "val" : "A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "enzyme inhibitors", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "inhibidor enzimatico", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "inhibidores enzimaticos", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "inhibiteur enzymatique", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "inhibiteurs enzymatiques", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_24431", "lbl" : "chemical entity", "type" : "CLASS", "meta" : { "definition" : { "val" : "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "chemical entity", "xrefs" : [ "UniProt" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_24432", "lbl" : "biological role", "type" : "CLASS", "meta" : { "definition" : { "val" : "A role played by the molecular entity or part thereof within a biological context." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "biological function", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_24433", "lbl" : "group", "type" : "CLASS", "meta" : { "definition" : { "val" : "A defined linked collection of atoms or a single atom within a molecular entity." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Gruppe", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Rest", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "groupe", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "grupo", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "grupos", "xrefs" : [ "IUPAC" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_24532", "lbl" : "organic heterocyclic compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cyclic compound having as ring members atoms of carbon and at least of one other element." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organic heterocycle", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "organic heterocyclic compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_24533", "lbl" : "heterodetic cyclic peptide", "type" : "CLASS", "meta" : { "definition" : { "val" : "A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "heterodetic cyclic peptides", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "peptide cyclique heterodetique", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "peptido ciclico heterodetico", "xrefs" : [ "IUPAC" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_24621", "lbl" : "hormone", "type" : "CLASS", "meta" : { "definition" : { "val" : "Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "endocrine", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "hormones", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_24651", "lbl" : "hydroxides", "type" : "CLASS", "meta" : { "definition" : { "val" : "Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-))." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_24828", "lbl" : "indoles", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any compound containing an indole skeleton." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_24833", "lbl" : "oxoacid", "type" : "CLASS", "meta" : { "definition" : { "val" : "A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "oxacids", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxiacids", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxo acid", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxy-acids", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxyacids", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_24834", "lbl" : "inorganic anion", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "inorganic anions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_24835", "lbl" : "inorganic molecular entity", "type" : "CLASS", "meta" : { "definition" : { "val" : "A molecular entity that contains no carbon." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "anorganische Verbindungen", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "inorganic compounds", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "inorganic entity", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "inorganic molecular entities", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "inorganics", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_24836", "lbl" : "inorganic oxide", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "inorganic oxides", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_24867", "lbl" : "monoatomic ion", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "monoatomic ions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_24870", "lbl" : "ion", "type" : "CLASS", "meta" : { "definition" : { "val" : "A molecular entity having a net electric charge." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Ion", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasExactSynonym", "val" : "ion", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Ionen", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "iones", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "ions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_25212", "lbl" : "metabolite", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "metabolites", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "primary metabolites", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "secondary metabolites", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:26619" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:35220" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_25362", "lbl" : "elemental molecule", "type" : "CLASS", "meta" : { "definition" : { "val" : "A molecule all atoms of which have the same atomic number." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "homoatomic molecule", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "homoatomic molecules", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_25367", "lbl" : "molecule", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any polyatomic entity that is an electrically neutral entity consisting of more than one atom." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "molecule", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "Molekuel", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "molecula", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "molecules", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "neutral molecular compounds", "xrefs" : [ "IUPAC" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_25375", "lbl" : "monoamine molecular messenger", "type" : "CLASS", "meta" : { "definition" : { "val" : "A group of neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "monamines", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "monoamines", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_25384", "lbl" : "monocarboxylic acid", "type" : "CLASS", "meta" : { "definition" : { "val" : "An oxoacid containing a single carboxy group." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "monocarboxylic acids", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_25512", "lbl" : "neurotransmitter", "type" : "CLASS", "meta" : { "definition" : { "val" : "An endogenous compound that is used to transmit information across the synapse between a neuron and another cell." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "neurotransmitters", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Neurotransmitter" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_25555", "lbl" : "nitrogen atom", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "7N", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "N", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "Stickstoff", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "azote", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "nitrogen", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "nitrogeno", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "WebElements:N" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_25585", "lbl" : "nonmetal atom", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Nichtmetall", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Nichtmetalle", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "no metal", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "no metales", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "non-metal", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "non-metaux", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "nonmetal", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "nonmetals", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_25696", "lbl" : "organic anion", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any organic ion with a net negative charge." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organic anions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_25697", "lbl" : "organic cation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any organic ion with a net positive charge." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organic cations", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_25699", "lbl" : "organic ion", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organic ions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_25704", "lbl" : "organic sulfate", "type" : "CLASS", "meta" : { "definition" : { "val" : "Compounds of the general formula SO3HOR where R is an organyl group" }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organic sulfates", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_25741", "lbl" : "oxide", "type" : "CLASS", "meta" : { "definition" : { "val" : "An oxide is a chemical compound of oxygen with other chemical elements." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "oxide", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxides", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_25805", "lbl" : "oxygen atom", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "8O", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "O", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "Sauerstoff", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxigeno", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxygen", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxygene", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C00007" }, { "val" : "WebElements:O" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_25806", "lbl" : "oxygen molecular entity", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "oxygen molecular entity", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxygen molecular entities", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_25905", "lbl" : "peptide hormone", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "peptide hormones", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "polypeptide hormone", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_26764", "lbl" : "steroid hormone", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any steroid that acts as hormone." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Steroidhormon", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Steroidhormone", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "hormona esteroide", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "hormonas esteroideas", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "hormone steroide", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "hormones steroides", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "steroid hormones", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_26819", "lbl" : "sulfuric ester", "type" : "CLASS", "meta" : { "definition" : { "val" : "An ester of an alcohol and sulfuric acid." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "sulfate ester", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "sulfuric acid ester", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "sulfuric acid esters", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_26820", "lbl" : "sulfates", "type" : "CLASS", "meta" : { "definition" : { "val" : "Salts and esters of sulfuric acid" }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "sulfates", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "sulfuric acid derivative", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "sulphates", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_26833", "lbl" : "sulfur atom", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "16S", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "Elemental sulfur", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "S", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "S", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Schwefel", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "azufre", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "soufre", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "sulfur", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "sulfur", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "sulphur", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "theion", "xrefs" : [ "IUPAC" ] } ], "xrefs" : [ { "val" : "KEGG:C00087" }, { "val" : "KEGG:D06527" }, { "val" : "PPDB:605" }, { "val" : "WebElements:S" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_26835", "lbl" : "sulfur molecular entity", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "sulfur molecular entity", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "sulfur molecular entities", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_26836", "lbl" : "sulfuric acid", "type" : "CLASS", "meta" : { "definition" : { "val" : "A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Sulfuric acid", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasExactSynonym", "val" : "sulfuric acid", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Acide sulfurique", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "Acido sulfurico", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "Acidum sulfuricum", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "H2SO4", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "Schwefelsaeureloesungen", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "[S(OH)2O2]", "xrefs" : [ "MolBase" ] }, { "pred" : "hasRelatedSynonym", "val" : "[SO2(OH)2]", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "sulphuric acid", "xrefs" : [ "MolBase" ] } ], "xrefs" : [ { "val" : "KEGG:C00059" }, { "val" : "KEGG:D05963" }, { "val" : "KNApSAcK:C00007530" }, { "val" : "MolBase:4" }, { "val" : "PPDB:606" }, { "val" : "Wikipedia:Sulfuric_acid" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_27027", "lbl" : "micronutrient", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "micronutrients", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "trace elements", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Micronutrient" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_27162", "lbl" : "tryptamines", "type" : "CLASS", "meta" : { "definition" : { "val" : "Tryptamine and its substitution derivatives." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_27171", "lbl" : "organic heterobicyclic compound", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "heterobicyclic compounds", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "organic heterobicyclic compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_27207", "lbl" : "univalent carboacyl group", "type" : "CLASS", "meta" : { "definition" : { "val" : "A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "univalent acyl group", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "univalent carboacyl groups", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "univalent carboxylic acyl groups", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_27369", "lbl" : "zwitterion", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "compose zwitterionique", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "compuestos zwitterionicos", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "zwitteriones", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "zwitterionic compounds", "xrefs" : [ "IUPAC" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_27594", "lbl" : "carbon atom", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "6C", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "C", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "C", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Carbon", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Kohlenstoff", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "carbon", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "carbone", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "carbonium", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "carbono", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C06265" }, { "val" : "WebElements:C" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:23009" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:3399" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_28616", "lbl" : "carbamic acid", "type" : "CLASS", "meta" : { "definition" : { "val" : "A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CARBAMIC ACID", "xrefs" : [ "PDBeChem" ] }, { "pred" : "hasExactSynonym", "val" : "Carbamic acid", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Aminoameisensaeure", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Aminoformic acid", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Carbamate", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Carbamidsaeure", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "DrugBank:DB04261" }, { "val" : "KEGG:C01563" }, { "val" : "PDBeChem:OUT" }, { "val" : "Wikipedia:Carbamic_acid" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:22504" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:23002" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:3386" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:44573" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_28790", "lbl" : "serotonin", "type" : "CLASS", "meta" : { "definition" : { "val" : "A primary amino compound that is the 5-hydroxy derivative of tryptamine." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "SEROTONIN", "xrefs" : [ "PDBeChem" ] }, { "pred" : "hasExactSynonym", "val" : "Serotonin", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "3-(2-Aminoethyl)-1H-indol-5-ol", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "5-HT", "xrefs" : [ "IUPHAR" ] }, { "pred" : "hasRelatedSynonym", "val" : "5-Hydroxytryptamine", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Enteramine", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "serotonine", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "thrombocytin", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "thrombotonin", "xrefs" : [ "ChemIDplus" ] } ], "xrefs" : [ { "val" : "HMDB:HMDB0000259" }, { "val" : "KEGG:C00780" }, { "val" : "KNApSAcK:C00001429" }, { "val" : "LINCS:LSM-6589" }, { "val" : "MetaCyc:SEROTONIN" }, { "val" : "PDBeChem:SRO" }, { "val" : "Wikipedia:Serotonin" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:1420" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:26652" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:49894" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_28938", "lbl" : "ammonium", "type" : "CLASS", "meta" : { "definition" : { "val" : "An onium cation obtained by protonation of ammonia." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "ammonium", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Ammonium(1+)", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "NH4(+)", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "NH4(+)", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "NH4+", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "[NH4](+)", "xrefs" : [ "MolBase" ] }, { "pred" : "hasRelatedSynonym", "val" : "ammonium cation", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "ammonium ion", "xrefs" : [ "PDBeChem" ] } ], "xrefs" : [ { "val" : "KEGG:C01342" }, { "val" : "MetaCyc:AMMONIUM" }, { "val" : "MolBase:929" }, { "val" : "PDBeChem:NH4" }, { "val" : "Wikipedia:Ammonium" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:22534" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:49783" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:7435" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_29067", "lbl" : "carboxylic acid anion", "type" : "CLASS", "meta" : { "definition" : { "val" : "The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "a carboxylate", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "carboxylic acid anions", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "carboxylic anions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13626" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13945" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:23026" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:58657" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_29337", "lbl" : "azanide", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "NH2(-)", "xrefs" : [ "IUPAC" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_29340", "lbl" : "hydridonitrate(2-)", "type" : "CLASS", "meta" : { "definition" : { "val" : "A divalent inorganic anion resulting from the removal of two protons from ammonia." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "NH(2-)", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "imide", "xrefs" : [ "IUPAC" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_29793", "lbl" : "hydridodioxygen(1+)", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "HO2(+)", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "HOO(+)", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "[HO2](+)", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_30089", "lbl" : "acetate", "type" : "CLASS", "meta" : { "definition" : { "val" : "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "acetate", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "ACETATE ION", "xrefs" : [ "PDBeChem" ] }, { "pred" : "hasRelatedSynonym", "val" : "Azetat", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "CH3-COO(-)", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "Ethanoat", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "MeCO2 anion", "xrefs" : [ "NIST_Chemistry_WebBook" ] }, { "pred" : "hasRelatedSynonym", "val" : "acetic acid, ion(1-)", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "ethanoate", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "DrugBank:DB03166" }, { "val" : "KEGG:C00033" }, { "val" : "MetaCyc:ACET" }, { "val" : "PDBeChem:ACT" }, { "val" : "Wikipedia:Acetate" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13704" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:22165" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:40480" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_30212", "lbl" : "photon", "type" : "CLASS", "meta" : { "definition" : { "val" : "Particle of zero charge, zero rest mass, spin quantum number 1, energy hnu and momentum hnu/c (h is the Planck constant, nu the frequency of radiation and c the speed of light), carrier of electromagnetic force." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Lichtquant", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Light", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "foton", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "gamma", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "hnu", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "hnu", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "light quantum", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C00205" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:10581" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:14383" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_32952", "lbl" : "amine", "type" : "CLASS", "meta" : { "definition" : { "val" : "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Amine", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Amin", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Substituted amine", "xrefs" : [ "KEGG_COMPOUND" ] } ], "xrefs" : [ { "val" : "KEGG:C00706" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13814" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:22474" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:2641" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_32988", "lbl" : "amide", "type" : "CLASS", "meta" : { "definition" : { "val" : "An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Amide", "xrefs" : [ "KEGG_COMPOUND" ] } ], "xrefs" : [ { "val" : "KEGG:C00241" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:22473" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:2633" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33232", "lbl" : "application", "type" : "CLASS", "meta" : { "definition" : { "val" : "Intended use of the molecular entity or part thereof by humans." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33233", "lbl" : "fundamental particle", "type" : "CLASS", "meta" : { "definition" : { "val" : "A particle not known to have substructure." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "elementary particles", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33238", "lbl" : "monoatomic entity", "type" : "CLASS", "meta" : { "definition" : { "val" : "A monoatomic entity is a molecular entity consisting of a single atom." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "atomic entity", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "monoatomic entities", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33241", "lbl" : "oxoacid derivative", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "oxoacid derivatives", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33242", "lbl" : "inorganic hydride", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "inorganic hydrides", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33246", "lbl" : "inorganic group", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any substituent group which does not contain carbon." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "inorganic groups", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33247", "lbl" : "organic group", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any substituent group or skeleton containing carbon." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organic groups", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33249", "lbl" : "organyl group", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any organic substituent group, regardless of functional type, having one free valence at a carbon atom." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "groupe organyle", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "grupo organilo", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "grupos organilo", "xrefs" : [ "IUPAC" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33250", "lbl" : "atom", "type" : "CLASS", "meta" : { "definition" : { "val" : "A chemical entity constituting the smallest component of an element having the chemical properties of the element." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "atome", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "atomo", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "atoms", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "atomus", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "element", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "elements", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:22671" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:23907" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33252", "lbl" : "atomic nucleus", "type" : "CLASS", "meta" : { "definition" : { "val" : "A nucleus is the positively charged central portion of an atom, excluding the orbital electrons." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Atomkern", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Kern", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "noyau", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "noyau atomique", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "nuclei", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "nucleo", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "nucleo atomico", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "nucleus atomi", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33253", "lbl" : "nucleon", "type" : "CLASS", "meta" : { "definition" : { "val" : "Heavy nuclear particle: proton or neutron." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "nucleon", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "Nukleon", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Nukleonen", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "nucleons", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33256", "lbl" : "primary amide", "type" : "CLASS", "meta" : { "definition" : { "val" : "A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "primary amide", "xrefs" : [ "IUPAC" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33259", "lbl" : "elemental molecular entity", "type" : "CLASS", "meta" : { "definition" : { "val" : "A molecular entity all atoms of which have the same atomic number." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "homoatomic entity", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "homoatomic molecular entities", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "homoatomic molecular entity", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33262", "lbl" : "elemental oxygen", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33263", "lbl" : "diatomic oxygen", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33273", "lbl" : "polyatomic anion", "type" : "CLASS", "meta" : { "definition" : { "val" : "An anion consisting of more than one atom." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "polyatomic anions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33280", "lbl" : "molecular messenger", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "chemical messenger", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33281", "lbl" : "antimicrobial agent", "type" : "CLASS", "meta" : { "definition" : { "val" : "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Antibiotika", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Antibiotikum", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "antibiotic", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "antibiotics", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "antibiotique", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "antimicrobial", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "antimicrobial agents", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "antimicrobials", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "microbicide", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "microbicides", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:22582" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33284", "lbl" : "nutrient", "type" : "CLASS", "meta" : { "definition" : { "val" : "A nutrient is a food component that an organism uses to survive and grow." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "nutrients", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33285", "lbl" : "heteroorganic entity", "type" : "CLASS", "meta" : { "definition" : { "val" : "A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "heteroorganic entities", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "organoelement compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33300", "lbl" : "pnictogen", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "group 15 elements", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "group V elements", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "nitrogenoideos", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "nitrogenoides", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "pnictogene", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "pnictogenes", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33302", "lbl" : "pnictogen molecular entity", "type" : "CLASS", "meta" : { "definition" : { "val" : "A p-block molecular entity containing any pnictogen." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "pnictogen molecular entity", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "pnictogen molecular entities", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33303", "lbl" : "chalcogen", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any p-block element belonging to the group 16 family of the periodic table." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Chalkogen", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Chalkogene", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "anfigeno", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "anfigenos", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "calcogeno", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "calcogenos", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "chalcogene", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "chalcogenes", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "group 16 elements", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "group VI elements", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33304", "lbl" : "chalcogen molecular entity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any p-block molecular entity containing a chalcogen." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "chalcogen molecular entity", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "chalcogen compounds", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "chalcogen molecular entities", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33306", "lbl" : "carbon group element atom", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "carbon group element", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "carbon group elements", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "carbonoides", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "cristallogene", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "cristallogenes", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "group IV elements", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33308", "lbl" : "carboxylic ester", "type" : "CLASS", "meta" : { "definition" : { "val" : "An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Carboxylic ester", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "a carboxylic ester", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "carboxylic acid esters", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C02391" }, { "val" : "Wikipedia:Ester" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13204" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:23028" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:3408" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33318", "lbl" : "main group element atom", "type" : "CLASS", "meta" : { "definition" : { "val" : "An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Hauptgruppenelement", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Hauptgruppenelemente", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "main group element", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33402", "lbl" : "sulfur oxoacid", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "oxoacids of sulfur", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "sulfur oxoacids", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33424", "lbl" : "sulfur oxoacid derivative", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "sulfur oxoacid derivative", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "sulfur oxoacid derivatives", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33482", "lbl" : "sulfur oxoanion", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "sulfur oxoanion", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxoanions of sulfur", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "sulfur oxoanions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33484", "lbl" : "chalcogen oxoacid", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "chalcogen oxoacid", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "chalcogen oxoacids", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33485", "lbl" : "chalcogen oxoanion", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "chalcogen oxoanion", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "chalcogen oxoanions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33558", "lbl" : "alpha-amino-acid anion", "type" : "CLASS", "meta" : { "definition" : { "val" : "An amino-acid anion obtained by deprotonation of any alpha-amino acid." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "alpha-amino-acid anion", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "alpha-amino acid anions", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "alpha-amino-acid anions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33559", "lbl" : "s-block element atom", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "s-block element", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "s-block elements", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33560", "lbl" : "p-block element atom", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any main group element atom belonging to the p-block of the periodic table." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "p-block element", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "p-block elements", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33566", "lbl" : "catechols", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any compound containing an o-diphenol component." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "1,2-benzenediols", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "a catechol", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "benzene-1,2-diols", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C15571" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:134187" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13628" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:18862" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33567", "lbl" : "catecholamine", "type" : "CLASS", "meta" : { "definition" : { "val" : "4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Catecholamine", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "catecholamines", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C02012" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:23056" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:3468" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33569", "lbl" : "noradrenaline", "type" : "CLASS", "meta" : { "definition" : { "val" : "A catecholamine in which C-1 of the aminoethyl side-chain is hydroxy-substituted." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "noradrenalina", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "norepinephrine", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "LINCS:LSM-5181" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33570", "lbl" : "benzenediols", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:22705" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:22711" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33571", "lbl" : "(S)-noradrenaline", "type" : "CLASS", "meta" : { "definition" : { "val" : "The S-enantiomer of noradrenaline." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "xrefs" : [ { "val" : "LINCS:LSM-37072" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33575", "lbl" : "carboxylic acid", "type" : "CLASS", "meta" : { "definition" : { "val" : "A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Carbonsaeure", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Carbonsaeuren", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Karbonsaeure", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "RC(=O)OH", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "acide carboxylique", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "acides carboxyliques", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "acido carboxilico", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "acidos carboxilicos", "xrefs" : [ "IUPAC" ] } ], "xrefs" : [ { "val" : "Wikipedia:Carboxylic_acid" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13428" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13627" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:23027" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33579", "lbl" : "main group molecular entity", "type" : "CLASS", "meta" : { "definition" : { "val" : "A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "main group compounds", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "main group molecular entities", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33582", "lbl" : "carbon group molecular entity", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "carbon group molecular entity", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "carbon group molecular entities", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33595", "lbl" : "cyclic compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any molecule that consists of a series of atoms joined together to form a ring." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "cyclic compounds", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Cyclic_compound" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33608", "lbl" : "hydrogen molecular entity", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "hydrogen compounds", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "hydrogen molecular entities", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33635", "lbl" : "polycyclic compound", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "polycyclic compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33636", "lbl" : "bicyclic compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "A molecule that features two fused rings." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "bicyclic compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33655", "lbl" : "aromatic compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "aromatics", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "aromatische Verbindungen", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33659", "lbl" : "organic aromatic compound", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organic aromatic compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33671", "lbl" : "heteropolycyclic compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "A polycyclic compound in which at least one of the rings contains at least one non-carbon atom." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "polyheterocyclic compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33672", "lbl" : "heterobicyclic compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33674", "lbl" : "s-block molecular entity", "type" : "CLASS", "meta" : { "definition" : { "val" : "An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "s-block molecular entity", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "s-block compounds", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "s-block molecular entities", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33675", "lbl" : "p-block molecular entity", "type" : "CLASS", "meta" : { "definition" : { "val" : "A main group molecular entity that contains one or more atoms of a p-block element." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "p-block compounds", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "p-block molecular entities", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "p-block molecular entitiy", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33692", "lbl" : "hydrides", "type" : "CLASS", "meta" : { "definition" : { "val" : "Hydrides are chemical compounds of hydrogen with other chemical elements." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33693", "lbl" : "oxygen hydride", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "oxygen hydride", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "hydrides of oxygen", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxygen hydrides", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33694", "lbl" : "biomacromolecule", "type" : "CLASS", "meta" : { "definition" : { "val" : "A macromolecule formed by a living organism." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Biopolymere", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "biomacromolecules", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "biopolymers", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33695", "lbl" : "information biomacromolecule", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "genetically encoded biomacromolecules", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "genetically encoded biopolymers", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "information biomacromolecules", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "information biopolymers", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "information macromolecule", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "information macromolecules", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33696", "lbl" : "nucleic acid", "type" : "CLASS", "meta" : { "definition" : { "val" : "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "NA", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Nukleinsaeure", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Nukleinsaeuren", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "acide nucleique", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "acides nucleiques", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "acido nucleico", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "acidos nucleicos", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33697", "lbl" : "ribonucleic acid", "type" : "CLASS", "meta" : { "definition" : { "val" : "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "ribonucleic acid", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "RNA", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "RNA", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "RNS", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Ribonukleinsaeure", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "pentosenucleic acids", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "ribonucleic acids", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "ribose nucleic acid", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "yeast nucleic acid", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33700", "lbl" : "proteinogenic amino-acid residue", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "canonical amino-acid residue", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "canonical amino-acid residues", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "common amino acid residues", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "proteinogenic amino-acid residues", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "standard amino acid residues", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "standard amino-acid residues", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33702", "lbl" : "polyatomic cation", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cation consisting of more than one atom." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "polyatomic cations", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33703", "lbl" : "amino-acid cation", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "amino-acid cation", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "amino acid cation", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "amino-acid cations", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33704", "lbl" : "alpha-amino acid", "type" : "CLASS", "meta" : { "definition" : { "val" : "An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Amino acid", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Amino acids", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "alpha-amino acids", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "alpha-amino acids", "xrefs" : [ "JCBN" ] }, { "pred" : "hasRelatedSynonym", "val" : "alpha-amino carboxylic acids", "xrefs" : [ "IUPAC" ] } ], "xrefs" : [ { "val" : "KEGG:C00045" }, { "val" : "KEGG:C05167" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:10208" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13779" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:22442" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:2642" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33708", "lbl" : "amino-acid residue", "type" : "CLASS", "meta" : { "definition" : { "val" : "When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "amino acid residue", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "amino-acid residues", "xrefs" : [ "JCBN" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33709", "lbl" : "amino acid", "type" : "CLASS", "meta" : { "definition" : { "val" : "A carboxylic acid containing one or more amino groups." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Aminocarbonsaeure", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Aminokarbonsaeure", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Aminosaeure", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "amino acids", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Amino_acid" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13815" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:22477" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33710", "lbl" : "alpha-amino-acid residue", "type" : "CLASS", "meta" : { "definition" : { "val" : "An amino-acid residue derived from an alpha-amino acid." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "alpha-amino-acid residues", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "an alpha-amino acid residue", "xrefs" : [ "UniProt" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33719", "lbl" : "alpha-amino-acid cation", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "alpha-amino-acid cation", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "alpha-amino acid cations", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "alpha-amino-acid cations", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33720", "lbl" : "carbohydrate acid", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "carbohydrate acid", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "carbohydrate acids", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33721", "lbl" : "carbohydrate acid anion", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "carbohydrate acid anion", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "carbohydrate acid anions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33791", "lbl" : "canonical nucleoside residue", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "canonical nucleoside residues", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "common nucleoside residues", "xrefs" : [ "CBN" ] }, { "pred" : "hasRelatedSynonym", "val" : "nucleoside residue", "xrefs" : [ "CBN" ] }, { "pred" : "hasRelatedSynonym", "val" : "standard nucleoside residues", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33792", "lbl" : "canonical ribonucleoside residue", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "N", "xrefs" : [ "CBN" ] }, { "pred" : "hasRelatedSynonym", "val" : "Nuc", "xrefs" : [ "CBN" ] }, { "pred" : "hasRelatedSynonym", "val" : "canonical ribonucleoside residues", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "common ribonucleoside residue", "xrefs" : [ "CBN" ] }, { "pred" : "hasRelatedSynonym", "val" : "common ribonucleoside residues", "xrefs" : [ "CBN" ] }, { "pred" : "hasRelatedSynonym", "val" : "standard ribonucleoside residues", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33822", "lbl" : "organic hydroxy compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "An organic compound having at least one hydroxy group attached to a carbon atom." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organic alcohol", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "organic hydroxy compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:64710" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33832", "lbl" : "organic cyclic compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any organic molecule that consists of atoms connected in the form of a ring." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organic cyclic compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33833", "lbl" : "heteroarene", "type" : "CLASS", "meta" : { "definition" : { "val" : "A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "hetarenes", "xrefs" : [ "IUPAC" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33837", "lbl" : "conjugated protein", "type" : "CLASS", "meta" : { "definition" : { "val" : "Conjugated protein is a protein that contains a non-peptide component, usually in stoichiometric proportion." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "complex protein", "xrefs" : [ "COMe" ] } ], "xrefs" : [ { "val" : "COMe:PRX000001" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33839", "lbl" : "macromolecule", "type" : "CLASS", "meta" : { "definition" : { "val" : "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "macromolecules", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "polymer", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "polymer molecule", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "polymers", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Macromolecule" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33853", "lbl" : "phenols", "type" : "CLASS", "meta" : { "definition" : { "val" : "Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Aryl alcohol", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "a phenol", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "arenols", "xrefs" : [ "IUPAC" ] } ], "xrefs" : [ { "val" : "KEGG:C15584" }, { "val" : "MetaCyc:Phenols" }, { "val" : "Wikipedia:Phenols" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13664" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13825" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:25969" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:2857" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33893", "lbl" : "reagent", "type" : "CLASS", "meta" : { "definition" : { "val" : "A substance used in a chemical reaction to detect, measure, examine, or produce other substances." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "reactif", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "reactivo", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "reagents", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_33937", "lbl" : "macronutrient", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "macronutrients", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_350546", "lbl" : "serotonin(1+)", "type" : "CLASS", "meta" : { "definition" : { "val" : "An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "serotonin", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "serotonin cation", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35106", "lbl" : "nitrogen hydride", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "nitrogen hydrides", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35107", "lbl" : "azane", "type" : "CLASS", "meta" : { "definition" : { "val" : "Saturated acyclic nitrogen hydrides having the general formula NnHn+2." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "azanes", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35222", "lbl" : "inhibitor", "type" : "CLASS", "meta" : { "definition" : { "val" : "A substance that diminishes the rate of a chemical reaction." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "inhibidor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "inhibiteur", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "inhibitors", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35223", "lbl" : "catalyst", "type" : "CLASS", "meta" : { "definition" : { "val" : "A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Katalysator", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "catalizador", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "catalyseur", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35238", "lbl" : "amino acid zwitterion", "type" : "CLASS", "meta" : { "definition" : { "val" : "The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "amino acid zwitterion", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35267", "lbl" : "quaternary ammonium ion", "type" : "CLASS", "meta" : { "definition" : { "val" : "A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Quaternary amine", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "a quaternary ammonium", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "quaternary ammonium ions", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C06703" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:26470" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:8693" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35274", "lbl" : "ammonium ion derivative", "type" : "CLASS", "meta" : { "definition" : { "val" : "A derivative of ammonium, NH4(+), in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "ammonium ion derivatives", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "azanium ion derivative", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "azanium ion derivatives", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35287", "lbl" : "acylcholine", "type" : "CLASS", "meta" : { "definition" : { "val" : "A choline ester formed from choline and a carboxylic acid." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "acylcholines", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "an acylcholine", "xrefs" : [ "UniProt" ] } ], "xrefs" : [ { "val" : "KEGG:C01777" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13245" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:22227" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:2463" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35341", "lbl" : "steroid", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Steroid", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "a steroid", "xrefs" : [ "UniProt" ] } ], "xrefs" : [ { "val" : "KEGG:C00377" }, { "val" : "MetaCyc:Steroids" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13687" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:26768" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:9263" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35352", "lbl" : "organonitrogen compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any heteroorganic entity containing at least one carbon-nitrogen bond." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organonitrogens", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35406", "lbl" : "oxoanion", "type" : "CLASS", "meta" : { "definition" : { "val" : "An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "oxoanion", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxoacid anions", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxoanions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:33274" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:33436" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35472", "lbl" : "anti-inflammatory drug", "type" : "CLASS", "meta" : { "definition" : { "val" : "A substance that reduces or suppresses inflammation." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "anti-inflammatory drugs", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "antiinflammatory agent", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "antiinflammatory drug", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "antiinflammatory drugs", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35524", "lbl" : "sympathomimetic agent", "type" : "CLASS", "meta" : { "definition" : { "val" : "A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "sympathomimetic", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "sympathomimetics", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35554", "lbl" : "cardiovascular drug", "type" : "CLASS", "meta" : { "definition" : { "val" : "A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "cardiovascular agent", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "cardiovascular drugs", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35569", "lbl" : "alpha-adrenergic agonist", "type" : "CLASS", "meta" : { "definition" : { "val" : "An agent that selectively binds to and activates alpha-adrenergic receptors." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "alpha-adrenergic agonists", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "alpha-adrenergic receptor agonist", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "alpha-adrenoceptor agonists", "xrefs" : [ "IUPHAR" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35605", "lbl" : "carbon oxoacid", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "carbon oxoacids", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxoacids of carbon", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35620", "lbl" : "vasodilator agent", "type" : "CLASS", "meta" : { "definition" : { "val" : "A drug used to cause dilation of the blood vessels." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "vasodilator", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "vasodilator agents", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35701", "lbl" : "ester", "type" : "CLASS", "meta" : { "definition" : { "val" : "A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Ester", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "esters", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C00287" }, { "val" : "Wikipedia:Ester" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:23960" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:4859" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35722", "lbl" : "sulfated glycosaminoglycan", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "glycosaminoglycan sulfate", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "glycosaminoglycan sulfates", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "sulfated glycosaminoglycans", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35724", "lbl" : "carbohydrate sulfate", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "carbohydrate sulfates", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "carbohydrate sulphates", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35757", "lbl" : "monocarboxylic acid anion", "type" : "CLASS", "meta" : { "definition" : { "val" : "A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Carboxylate", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Monocarboxylate", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "a monocarboxylate", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "monocarboxylates", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "monocarboxylic acid anions", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C00060" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13657" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:25382" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:3407" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35881", "lbl" : "pnictogen hydride", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "pnictogen hydride", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "pnictogen hydrides", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_35942", "lbl" : "neurotransmitter agent", "type" : "CLASS", "meta" : { "definition" : { "val" : "A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "neurotransmitter agents", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_36080", "lbl" : "protein", "type" : "CLASS", "meta" : { "definition" : { "val" : "A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13677" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:14911" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_36338", "lbl" : "lepton", "type" : "CLASS", "meta" : { "definition" : { "val" : "Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "leptons", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_36339", "lbl" : "baryon", "type" : "CLASS", "meta" : { "definition" : { "val" : "Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "baryons", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_36340", "lbl" : "fermion", "type" : "CLASS", "meta" : { "definition" : { "val" : "Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "fermions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_36341", "lbl" : "boson", "type" : "CLASS", "meta" : { "definition" : { "val" : "Particle of integer spin quantum number following Bose-Einstein statistics. Bosons are named after Satyendra Nath Bose." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "bosons", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_36342", "lbl" : "subatomic particle", "type" : "CLASS", "meta" : { "definition" : { "val" : "A particle smaller than an atom." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "subatomic particles", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Subatomic_particle" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_36343", "lbl" : "composite particle", "type" : "CLASS", "meta" : { "definition" : { "val" : "A subatomic particle known to have substructure (i.e. consisting of smaller particles)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "composite particles", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_36344", "lbl" : "hadron", "type" : "CLASS", "meta" : { "definition" : { "val" : "Hadron is a subatomic particle which experiences the strong force." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "hadrons", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_36347", "lbl" : "nuclear particle", "type" : "CLASS", "meta" : { "definition" : { "val" : "A nucleus or any of its constituents in any of their energy states." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_36357", "lbl" : "polyatomic entity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any molecular entity consisting of more than one atom." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "polyatomic entities", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_36358", "lbl" : "polyatomic ion", "type" : "CLASS", "meta" : { "definition" : { "val" : "An ion consisting of more than one atom." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "polyatomic ions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_36586", "lbl" : "carbonyl compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_36587", "lbl" : "organic oxo compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organic oxo compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_36902", "lbl" : "chalcogen hydride", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "chalcogen hydride", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "chalcogen hydrides", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_36914", "lbl" : "inorganic ion", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "inorganic ions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_36915", "lbl" : "inorganic cation", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "inorganic cations", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_36916", "lbl" : "cation", "type" : "CLASS", "meta" : { "definition" : { "val" : "A monoatomic or polyatomic species having one or more elementary charges of the proton." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Cation", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasExactSynonym", "val" : "cation", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Kation", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Kationen", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "cationes", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "cations", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C01373" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:23058" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:3473" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_36962", "lbl" : "organochalcogen compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "An organochalcogen compound is a compound containing at least one carbon-chalcogen bond." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "organochalcogen compound", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "organochalcogen compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_36963", "lbl" : "organooxygen compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "An organochalcogen compound containing at least one carbon-oxygen bond." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "organooxygen compound", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "organooxygen compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_37022", "lbl" : "amino-acid anion", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "amino-acid anion", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "amino acid anions", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "amino-acid anions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_37176", "lbl" : "mononuclear parent hydride", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "mononuclear hydride", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "mononuclear hydrides", "xrefs" : [ "IUPAC" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_37395", "lbl" : "mucopolysaccharide", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any of the group of polysaccharides composed of alternating units from uronic acids and glycosamines, and commonly partially esterified with sulfuric acid." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Mucopolysaccharide", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Mucopolysaccharid", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Mukopolysaccharid", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "mucopolisacarido", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "mucopolisacaridos", "xrefs" : [ "IUPAC" ] } ], "xrefs" : [ { "val" : "KEGG:C05114" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:25425" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:7011" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_37527", "lbl" : "acid", "type" : "CLASS", "meta" : { "definition" : { "val" : "An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Acid", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Saeure", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Saeuren", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "acide", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "acido", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "acids", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C00174" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13800" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13801" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:22209" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:2426" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_37577", "lbl" : "heteroatomic molecular entity", "type" : "CLASS", "meta" : { "definition" : { "val" : "A molecular entity consisting of two or more chemical elements." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "chemical compound", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "heteroatomic molecular entities", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_37622", "lbl" : "carboxamide", "type" : "CLASS", "meta" : { "definition" : { "val" : "An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "carboxamides", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "primary carboxamide", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:35354" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:35355" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_37826", "lbl" : "sulfuric acid derivative", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "sulfuric acid derivative", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "sulfuric acid derivatives", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_37838", "lbl" : "carboacyl group", "type" : "CLASS", "meta" : { "definition" : { "val" : "A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "carboxylic acyl groups", "xrefs" : [ "IUPAC" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_37886", "lbl" : "adrenergic agonist", "type" : "CLASS", "meta" : { "definition" : { "val" : "An agent that selectively binds to and activates adrenergic receptors." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "adrenergic agonists", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "adrenergic receptor agonist", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "adrenoceptor agonists", "xrefs" : [ "IUPHAR" ] }, { "pred" : "hasRelatedSynonym", "val" : "adrenomimetic", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "adrenomimetics", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_37962", "lbl" : "adrenergic agent", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "adrenergic agents", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "adrenergic drug", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "adrenergic drugs", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "adrenergic neuron agents", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "adrenergics", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_38101", "lbl" : "organonitrogen heterocyclic compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "heterocyclic organonitrogen compounds", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "organonitrogen heterocyclic compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_38166", "lbl" : "organic heteropolycyclic compound", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organic heteropolycyclic compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:25429" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:38075" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_38180", "lbl" : "polycyclic heteroarene", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "polycyclic heteroarenes", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_38323", "lbl" : "cholinergic drug", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "cholinergic agent", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "cholinergic drugs", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "cholinomimetic", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_38324", "lbl" : "cholinergic agonist", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any drug that binds to and activates cholinergic receptors." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "acetylcholine agonist", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "acetylcholine agonists", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "acetylcholine receptor agonist", "xrefs" : [ "IUPHAR" ] }, { "pred" : "hasRelatedSynonym", "val" : "cholinergic agonists", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "cholinomimetic", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "cholinomimetics", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_38325", "lbl" : "muscarinic agonist", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any drug that binds to and activates a muscarinic cholinergic receptor." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "muscarinic acetylcholine receptor agonist", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "muscarinic agonists", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "muscarinic cholinergic agonist", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "muscarinic cholinergic agonists", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_38631", "lbl" : "aminoalkylindole", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "aminoalkylindoles", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:22503" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:24792" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_38958", "lbl" : "indole alkaloid", "type" : "CLASS", "meta" : { "definition" : { "val" : "An alkaloid containing an indole skeleton." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Indole alkaloid", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "indole alkaloids", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C06073" }, { "val" : "Wikipedia:Indole_alkaloid" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:24795" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:5901" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_39141", "lbl" : "Bronsted acid", "type" : "CLASS", "meta" : { "definition" : { "val" : "A molecular entity capable of donating a hydron to an acceptor (Bronsted base)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Bronsted-Saeure", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "acide de Bronsted", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "donneur d'hydron", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "hydron donor", "xrefs" : [ "IUPAC" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_39142", "lbl" : "Bronsted base", "type" : "CLASS", "meta" : { "definition" : { "val" : "A molecular entity capable of accepting a hydron from a donor (Bronsted acid)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Bronsted-Base", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "accepteur d'hydron", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "base de Bronsted", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "hydron acceptor", "xrefs" : [ "IUPAC" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_39144", "lbl" : "Lewis base", "type" : "CLASS", "meta" : { "definition" : { "val" : "A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Lewis-Base", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "base de Lewis", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "donneur d'une paire d'electrons", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "electron donor", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_43176", "lbl" : "hydroxy group", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "HYDROXY GROUP", "xrefs" : [ "PDBeChem" ] }, { "pred" : "hasExactSynonym", "val" : "hydroxy group", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "-OH", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "hydroxyl", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "hydroxyl group", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "PDBeChem:OH" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:24706" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:43171" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_45696", "lbl" : "hydrogensulfate", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "hydrogensulfate", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "HSO4(-)", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "HYDROGEN SULFATE", "xrefs" : [ "PDBeChem" ] }, { "pred" : "hasRelatedSynonym", "val" : "[SO3(OH)](-)", "xrefs" : [ "IUPAC" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:29199" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:45693" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_46629", "lbl" : "oxo group", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "OXO GROUP", "xrefs" : [ "PDBeChem" ] }, { "pred" : "hasRelatedSynonym", "val" : "=O", "xrefs" : [ "IUPAC" ] } ], "xrefs" : [ { "val" : "PDBeChem:O" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:29353" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:44607" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_46662", "lbl" : "mineral", "type" : "CLASS", "meta" : { "definition" : { "val" : "In general, a mineral is a chemical substance that is normally crystalline formed and has been formed as a result of geological processes. The term also includes metamict substances (naturally occurring, formerly crystalline substances whose crystallinity has been destroyed by ionising radiation) and can include naturally occurring amorphous substances that have never been crystalline ('mineraloids') such as georgite and calciouranoite as well as substances formed by the action of geological processes on bigenic compounds ('biogenic minerals')." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mineral", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Minerale", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "minerales", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "minerals", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "mineraux", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Mineral" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_46723", "lbl" : "phosphate mineral", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "phosphate minerals", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_46787", "lbl" : "solvent", "type" : "CLASS", "meta" : { "definition" : { "val" : "A liquid that can dissolve other substances (solutes) without any change in their chemical composition." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Loesungsmittel", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "solvant", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "solvents", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Solvent" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_46883", "lbl" : "carboxy group", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CARBOXY GROUP", "xrefs" : [ "PDBeChem" ] }, { "pred" : "hasRelatedSynonym", "val" : "-C(O)OH", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "-CO2H", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "-COOH", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "carboxyl group", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "PDBeChem:FMT" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:23025" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:41420" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_47622", "lbl" : "acetate ester", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any carboxylic ester where the carboxylic acid component is acetic acid." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Acetic ester", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Acetyl ester", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "acetate", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "acetate esters", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "acetates", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "acetyl esters", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "an acetyl ester", "xrefs" : [ "UniProt" ] } ], "xrefs" : [ { "val" : "KEGG:C01883" }, { "val" : "Wikipedia:Acetate#Esters" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13244" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:13799" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:22189" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:2406" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_48154", "lbl" : "sulfur oxide", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Schwefeloxide", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxides of sulfur", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "sulfur oxides", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_48354", "lbl" : "polar solvent", "type" : "CLASS", "meta" : { "definition" : { "val" : "A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "polar solvents", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_48356", "lbl" : "protic solvent", "type" : "CLASS", "meta" : { "definition" : { "val" : "A polar solvent that is capable of acting as a hydron (proton) donor." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_48539", "lbl" : "alpha-adrenergic drug", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any drug that acts on an alpha-adrenergic receptor." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "alpha-adrenergic drugs", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_48705", "lbl" : "agonist", "type" : "CLASS", "meta" : { "definition" : { "val" : "Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "agonista", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "agoniste", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "agonists", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_49637", "lbl" : "hydrogen atom", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "1H", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "H", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "Wasserstoff", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "hidrogeno", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "hydrogen", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "hydrogene", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "WebElements:H" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:24634" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:49636" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_50047", "lbl" : "organic amino compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organic amino compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_50297", "lbl" : "canonical nucleotide residue", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "canonical nucleotide residues", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_50299", "lbl" : "canonical ribonucleotide residue", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "canonical ribonucleotide residues", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_50312", "lbl" : "onium compound", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#1_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_50313", "lbl" : "onium cation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "onium cations", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "onium ion", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "onium ions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_50319", "lbl" : "nucleotide residue", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "nucleotide residues", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_50320", "lbl" : "nucleoside residue", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "nucleoside residues", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_50514", "lbl" : "vasoconstrictor agent", "type" : "CLASS", "meta" : { "definition" : { "val" : "Drug used to cause constriction of the blood vessels." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_50860", "lbl" : "organic molecular entity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any molecular entity that contains carbon." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organic compounds", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "organic entity", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "organic molecular entities", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:25700" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:33244" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_50906", "lbl" : "role", "type" : "CLASS", "meta" : { "definition" : { "val" : "A role is particular behaviour which a material entity may exhibit." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_50910", "lbl" : "neurotoxin", "type" : "CLASS", "meta" : { "definition" : { "val" : "A poison that interferes with the functions of the nervous system." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "agente neurotoxico", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "nerve poison", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "nerve poisons", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "neurotoxic agent", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "neurotoxic agents", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "neurotoxicant", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "neurotoxins", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Neurotoxin" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:50911" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_50994", "lbl" : "primary amino compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "primary amino compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_51086", "lbl" : "chemical role", "type" : "CLASS", "meta" : { "definition" : { "val" : "A role played by the molecular entity or part thereof within a chemical context." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_51143", "lbl" : "nitrogen molecular entity", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Nitrogenous compounds", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "nitrogen compounds", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "nitrogen molecular entities", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "KEGG:C06061" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:25556" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:7594" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_51151", "lbl" : "dipolar compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "dipolar compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_51422", "lbl" : "organodiyl group", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organodiyl groups", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_51446", "lbl" : "organic divalent group", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#1_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_51447", "lbl" : "organic univalent group", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#1_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_51958", "lbl" : "organic polycyclic compound", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organic polycyclic compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_52206", "lbl" : "biochemical role", "type" : "CLASS", "meta" : { "definition" : { "val" : "A biological role played by the molecular entity or part thereof within a biochemical context." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_52209", "lbl" : "aetiopathogenetic role", "type" : "CLASS", "meta" : { "definition" : { "val" : "A role played by the molecular entity or part thereof which causes the development of a pathological process." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "etiopathogenetic agent", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "etiopathogenetic role", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_52210", "lbl" : "pharmacological role", "type" : "CLASS", "meta" : { "definition" : { "val" : "A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_52211", "lbl" : "physiological role", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/chebi#1_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_52217", "lbl" : "pharmaceutical", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any substance introduced into a living organism with therapeutic or diagnostic purpose." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "farmaco", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "medicament", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "pharmaceuticals", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:33293" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:33294" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_52254", "lbl" : "apatite", "type" : "CLASS", "meta" : { "definition" : { "val" : "A phosphate mineral with the general formula Ca5(PO4)3X where X = OH, F or Cl." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "hydroxyapatite", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "HMDB:HMDB0033610" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_52255", "lbl" : "hydroxylapatite", "type" : "CLASS", "meta" : { "definition" : { "val" : "A phosphate mineral with the formula Ca5(PO4)3(OH)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_52845", "lbl" : "cyclic organic group", "type" : "CLASS", "meta" : { "definition" : { "val" : "An organic group that consists of a closed ring. It may be a substituent or a skeleton." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "cyclic organic groups", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_53309", "lbl" : "polyanionic macromolecule", "type" : "CLASS", "meta" : { "definition" : { "val" : "A polymer carrying multiple negative charges." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "polyanion", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "polyanions", "xrefs" : [ "SUBMITTER" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_53368", "lbl" : "ionic macromolecule", "type" : "CLASS", "meta" : { "definition" : { "val" : "A macromolecule containing ionic groups." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "ionic polymer", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "polyionic macromolecule", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_5391", "lbl" : "glucagon", "type" : "CLASS", "meta" : { "definition" : { "val" : "A 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Glucagon", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Glucagone", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "HSQGTFTSDYSKYLDSRRAQDFVQWLMNT", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "His-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-ala-glu(NH2)-asp-phe-val-glu(NH2)-trp-leu-met-asp(NH2)-thr", "xrefs" : [ "ChemIDplus" ] } ], "xrefs" : [ { "val" : "DrugBank:DB00040" }, { "val" : "KEGG:C01501" }, { "val" : "KEGG:D00116" }, { "val" : "Wikipedia:Glucagon" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_5686", "lbl" : "heterocyclic compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cyclic compound having as ring members atoms of at least two different elements." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Heterocyclic compound", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "compuesto heterociclico", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "compuestos heterociclicos", "xrefs" : [ "IUPAC" ] }, { "pred" : "hasRelatedSynonym", "val" : "heterocycle", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "heterocyclic compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_57887", "lbl" : "tryptaminium", "type" : "CLASS", "meta" : { "definition" : { "val" : "An ammonium ion that is the conjugate acid of tryptamine arising from protonation of the primary amino group; major species at pH 7.3." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "tryptamine", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "tryptaminium cation", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "tryptaminium(1+)", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_58942", "lbl" : "cationic amino-acid residue", "type" : "CLASS", "meta" : { "definition" : { "val" : "An amino-acid residue protonated on nitrogen." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "amino acid cation residue", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "amino acid cation residues", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "amino-acid cation residue", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "amino-acid cation residues", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "cationic amino acid residue", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "cationic amino acid residues", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "cationic amino-acid residues", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_58958", "lbl" : "organosulfate oxoanion", "type" : "CLASS", "meta" : { "definition" : { "val" : "An organic anion of general formula RS(=O)2O(-) where R is an organyl group." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organosulfate oxoanions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_59740", "lbl" : "nucleophilic reagent", "type" : "CLASS", "meta" : { "definition" : { "val" : "A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "nucleophile", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "nucleophiles", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "nucleophilic reagents", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_59999", "lbl" : "chemical substance", "type" : "CLASS", "meta" : { "definition" : { "val" : "A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Chemische Substanz", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_60004", "lbl" : "mixture", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Mischung", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_60027", "lbl" : "polymer", "type" : "CLASS", "meta" : { "definition" : { "val" : "A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc.." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Polymer", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Kunststoff", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Polymer" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_60164", "lbl" : "ionic polymer", "type" : "CLASS", "meta" : { "definition" : { "val" : "An ionic polymer is a polymer, composed of ionic macromolecules." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "polyionic polymer", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_60242", "lbl" : "monovalent inorganic cation", "type" : "CLASS", "meta" : { "definition" : { "val" : "An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "a monovalent cation", "xrefs" : [ "UniProt" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_60466", "lbl" : "peptide zwitterion", "type" : "CLASS", "meta" : { "definition" : { "val" : "Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "a peptide", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "peptide zwitterions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_61120", "lbl" : "nucleobase-containing molecular entity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any compound that has a nucleobase as a part." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "nucleobase-containing compound", "xrefs" : [ "SUBMITTER" ] }, { "pred" : "hasRelatedSynonym", "val" : "nucleobase-containing compounds", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "nucleobase-containing molecular entities", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_61469", "lbl" : "polyanionic polymer", "type" : "CLASS", "meta" : { "definition" : { "val" : "A polymer, composed of polyanion macromolecules." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "polyanion", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "polyanions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_63248", "lbl" : "oxidising agent", "type" : "CLASS", "meta" : { "definition" : { "val" : "A substance that removes electrons from another reactant in a redox reaction." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "oxidant", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxidants", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxidiser", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxidisers", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxidising agents", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxidizer", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxidizers", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxidizing agent", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "oxidizing agents", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_63299", "lbl" : "carbohydrate derivative", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "carbohydrate derivatives", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "derivatised carbohydrate", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "derivatised carbohydrates", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "derivatized carbohydrate", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "derivatized carbohydrates", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_63436", "lbl" : "carbohydrate acid derivative", "type" : "CLASS", "meta" : { "definition" : { "val" : "A carbohydrate derivative that is formally obtained from a carbohydrate acid." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "carbohydrate acid derivatives", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_63534", "lbl" : "monoamine", "type" : "CLASS", "meta" : { "definition" : { "val" : "An aralylamino compound which contains one amino group connected to an aromatic ring by a two-carbon chain. Monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "monoamines", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "naturally occurring monoamine", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "naturally occurring monoamines", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_63551", "lbl" : "carbohydrate acid derivative anion", "type" : "CLASS", "meta" : { "definition" : { "val" : "A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "carbohydrate acid anion derivative", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "carbohydrate acid anion derivatives", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "carbohydrate acid derivative anions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_64047", "lbl" : "food additive", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any substance which is added to food to preserve or enhance its flavour and/or appearance." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "food additives", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Food_additive" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_64049", "lbl" : "food acidity regulator", "type" : "CLASS", "meta" : { "definition" : { "val" : "A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "acidity regulator", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "acidity regulators", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "food acidity regulators", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "pH control agent", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "pH control agents", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Acidity_regulator" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_64365", "lbl" : "aralkylamino compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "An organic amino compound in which an aminoalkyl group is linked to an arene." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "aralkylamino compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_64628", "lbl" : "somatostatin", "type" : "CLASS", "meta" : { "definition" : { "val" : "A fourteen-membered heterodetic cyclic peptide comprising the sequence Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys cyclised by a disulfide bridge between the two Cys residues at positions 3 and 14." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Ala-Gly-cyclo-[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys]", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine cyclic (3-14) disulfide", "xrefs" : [ "ChemIDplus" ] }, { "pred" : "hasRelatedSynonym", "val" : "Somatostatin-1", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Somatostatin-14", "xrefs" : [ "KEGG_COMPOUND" ] }, { "pred" : "hasRelatedSynonym", "val" : "Synthetic growth hormone release-inhibiting hormone", "xrefs" : [ "ChemIDplus" ] } ], "xrefs" : [ { "val" : "HMDB:HMDB0013072" }, { "val" : "KEGG:C16022" }, { "val" : "KEGG:D07431" }, { "val" : "LINCS:LSM-5326" }, { "val" : "Wikipedia:Somatostatin" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_64708", "lbl" : "one-carbon compound", "type" : "CLASS", "meta" : { "definition" : { "val" : "An organic molecular entity containing a single carbon atom (C1)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "one-carbon compounds", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_64709", "lbl" : "organic acid", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any organic molecular entity that is acidic and contains carbon in covalent linkage." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organic acids", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_64766", "lbl" : "cationic group", "type" : "CLASS", "meta" : { "definition" : { "val" : "A group that carries an overall positive charge." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "cationic groups", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_64767", "lbl" : "anionic group", "type" : "CLASS", "meta" : { "definition" : { "val" : "A group that carries an overall negative charge." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "anionic groups", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_64769", "lbl" : "organic cationic group", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cationic group that contains carbon." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organic cationic groups", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_64775", "lbl" : "organic anionic group", "type" : "CLASS", "meta" : { "definition" : { "val" : "An anionic group that contains carbon." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organic anionic groups", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_64898", "lbl" : "anionic amino-acid residue", "type" : "CLASS", "meta" : { "definition" : { "val" : "An amino-acid residue carrying an overall negative charge." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "amino acid anion residue", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "amino acid anion residues", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "amino-acid anion residue", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "amino-acid anion residues", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "anionic amino acid residue", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "anionic amino acid residues", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "anionic amino-acid residues", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_64909", "lbl" : "poison", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "poisonous agent", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "poisonous agents", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "poisonous substance", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "poisonous substances", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "poisons", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "toxic agent", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "toxic agents", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "toxic substance", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "toxic substances", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Poison" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_65212", "lbl" : "polysaccharide derivative", "type" : "CLASS", "meta" : { "definition" : { "val" : "A carbohydrate derivative that is any derivative of a polysaccharide." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "polysaccharide derivatives", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_65255", "lbl" : "food preservative", "type" : "CLASS", "meta" : { "definition" : { "val" : "Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "food preservatives", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_65256", "lbl" : "antimicrobial food preservative", "type" : "CLASS", "meta" : { "definition" : { "val" : "A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "antimicrobial food preservatives", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "antimicrobial preservative", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "antimicrobial preservatives", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_65296", "lbl" : "primary ammonium ion", "type" : "CLASS", "meta" : { "definition" : { "val" : "An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "a primary amine", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "substituted ammonium", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_67079", "lbl" : "anti-inflammatory agent", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any compound that has anti-inflammatory effects." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "anti-inflammatory agents", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "antiinflammatory agent", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "antiinflammatory agents", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_72587", "lbl" : "(R)-noradrenaline(1+)", "type" : "CLASS", "meta" : { "definition" : { "val" : "An organic cation that is the conjugate acid of (R)-noradrenaline, obtained by protonation of the priamry amino group; major species at pH 7.3." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "(R)-noradrenaline", "xrefs" : [ "UniProt" ] }, { "pred" : "hasRelatedSynonym", "val" : "(R)-noradrenaline cation", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "(R)-noradrenalinium cation", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "(R)-noradrenalinium(1+)", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "PDBeChem:E5E" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_72695", "lbl" : "organic molecule", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any molecule that consists of at least one carbon atom as part of the electrically neutral entity." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organic compound", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "organic compounds", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "organic molecules", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_72813", "lbl" : "exopolysaccharide", "type" : "CLASS", "meta" : { "definition" : { "val" : "A biomacromolecule composed of carbohydrate residues which is secreted by a microorganism into the surrounding environment." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "exopolysaccharides", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "extracellular polymeric substance", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "extracellular polymeric substances", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "MetaCyc:Exopolysaccharides" }, { "val" : "Wikipedia:Exopolysaccharide" }, { "val" : "Wikipedia:Extracellular_polymeric_substance" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_73398", "lbl" : "indole skeleton", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_73541", "lbl" : "organic heterobicyclic ring", "type" : "CLASS", "meta" : { "definition" : { "val" : "A bicyclic organic group that contains both carbon and hetero atoms." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "organic heterobicyclic rings", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_75763", "lbl" : "eukaryotic metabolite", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "eukaryotic metabolites", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_75767", "lbl" : "animal metabolite", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "animal metabolites", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:77721" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:77743" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_75768", "lbl" : "mammalian metabolite", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any animal metabolite produced during a metabolic reaction in mammals." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "mammalian metabolites", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:77464" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:77744" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_75771", "lbl" : "mouse metabolite", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Mus musculus metabolite", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Mus musculus metabolites", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "mouse metabolites", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_75772", "lbl" : "Saccharomyces cerevisiae metabolite", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "S. cerevisiae metabolite", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "S. cerevisiae metabolites", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "S. cerevisiae secondary metabolite", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "S. cerevisiae secondary metabolites", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Saccharomyces cerevisiae metabolites", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Saccharomyces cerevisiae secondary metabolites", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "baker's yeast metabolite", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "baker's yeast metabolites", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "baker's yeast secondary metabolite", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "baker's yeast secondary metabolites", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:76949" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:76951" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_75787", "lbl" : "prokaryotic metabolite", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "prokaryotic metabolites", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_76206", "lbl" : "xenobiotic metabolite", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any metabolite produced by metabolism of a xenobiotic compound." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "xenobiotic metabolites", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_76759", "lbl" : "EC 3.* (hydrolase) inhibitor", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "EC 3.* (hydrolase) inhibitors", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "EC 3.* inhibitor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "EC 3.* inhibitors", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "EC 3.*.*.* inhibitor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "EC 3.*.*.* inhibitors", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "hydrolase (EC 3.*) inhibitor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "hydrolase (EC 3.*) inhibitors", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "hydrolase inhibitor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "hydrolase inhibitors", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Hydrolase" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_76764", "lbl" : "EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "EC 3.5.* inhibitor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "EC 3.5.* inhibitors", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_76807", "lbl" : "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor", "type" : "CLASS", "meta" : { "definition" : { "val" : "An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "EC 3.5.1.* inhibitor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "EC 3.5.1.* inhibitors", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_76924", "lbl" : "plant metabolite", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "plant metabolites", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "plant secondary metabolites", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:75766" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:76925" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_76946", "lbl" : "fungal metabolite", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "fungal metabolites", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:75765" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:76947" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_76967", "lbl" : "human xenobiotic metabolite", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any human metabolite produced by metabolism of a xenobiotic compound in humans." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "human xenobiotic metabolites", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_76969", "lbl" : "bacterial metabolite", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any prokaryotic metabolite produced during a metabolic reaction in bacteria." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:75760" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:76970" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_76971", "lbl" : "Escherichia coli metabolite", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any bacterial metabolite produced during a metabolic reaction in Escherichia coli." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "E.coli metabolite", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "E.coli metabolites", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Escherichia coli metabolites", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_77746", "lbl" : "human metabolite", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "H. sapiens metabolite", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "H. sapiens metabolites", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Homo sapiens metabolite", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "Homo sapiens metabolites", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:75770" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:77123" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_77941", "lbl" : "EC 3.5.1.4 (amidase) inhibitor", "type" : "CLASS", "meta" : { "definition" : { "val" : "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4)." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "EC 3.5.1.4 (amidase) inhibitors", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "EC 3.5.1.4 inhibitor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "EC 3.5.1.4 inhibitors", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "N-acetylaminohydrolase inhibitor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "N-acetylaminohydrolase inhibitors", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "acylamidase inhibitor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "acylamidase inhibitors", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "acylamide amidohydrolase inhibitor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "acylamide amidohydrolase inhibitors", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "amidase (EC 3.5.1.4) inhibitor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "amidase (EC 3.5.1.4) inhibitors", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "amidase inhibitor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "amidase inhibitors", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "amidohydrolase inhibitor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "amidohydrolase inhibitors", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "deaminase inhibitor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "deaminase inhibitors", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "fatty acylamidase inhibitor", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "fatty acylamidase inhibitors", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Amidase" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_77974", "lbl" : "food packaging gas", "type" : "CLASS", "meta" : { "definition" : { "val" : "A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "food packaging gases", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Packaging_gas" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_78295", "lbl" : "food component", "type" : "CLASS", "meta" : { "definition" : { "val" : "A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "dietary component", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "dietary components", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "food components", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_78433", "lbl" : "refrigerant", "type" : "CLASS", "meta" : { "definition" : { "val" : "A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a \"R\" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "refrigerants", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Refrigerant" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_78608", "lbl" : "alpha-amino acid zwitterion", "type" : "CLASS", "meta" : { "definition" : { "val" : "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "an alpha-amino acid", "xrefs" : [ "UniProt" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "CHEBI:83409" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_78616", "lbl" : "carbohydrates and carbohydrate derivatives", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "carbohydrates and derivatives", "xrefs" : [ "ChEBI" ] }, { "pred" : "hasRelatedSynonym", "val" : "carbohydrates and their derivatives", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_79388", "lbl" : "divalent inorganic anion", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any inorganic anion with a valency of two." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "divalent inorganic anions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_79389", "lbl" : "monovalent inorganic anion", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any inorganic anion with a valency of one." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "monovalent inorganic anions", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_83039", "lbl" : "crustacean metabolite", "type" : "CLASS", "meta" : { "definition" : { "val" : "An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "crustacean metabolites", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_83056", "lbl" : "Daphnia magna metabolite", "type" : "CLASS", "meta" : { "definition" : { "val" : "A Daphnia metabolite produced by the species Daphnia magna." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Daphnia magna metabolites", "xrefs" : [ "ChEBI" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_83057", "lbl" : "Daphnia metabolite", "type" : "CLASS", "meta" : { "definition" : { "val" : "A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia" }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Daphnia metabolites", "xrefs" : [ "ChEBI" ] } ], "xrefs" : [ { "val" : "Wikipedia:Daphnia" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CHEBI_84729", "lbl" : "hydroxyindoles", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any member of the class of indoles carrying at least one hydroxy group." }, "subsets" : [ "http://purl.obolibrary.org/obo/chebi#3_STAR" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "chebi_ontology" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000000", "lbl" : "cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.", "xrefs" : [ "CARO:mah" ] }, "comments" : [ "The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one)." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], "xrefs" : [ { "val" : "CALOHA:TS-2035" }, { "val" : "FMA:68646" }, { "val" : "GO:0005623" }, { "val" : "KUPO:0000002" }, { "val" : "MESH:D002477" }, { "val" : "VHOG:0001533" }, { "val" : "WBbt:0004017" }, { "val" : "XAO:0003012" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000005", "lbl" : "neural crest derived fibroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any fibroblast that is derived from the neural crest.", "xrefs" : [ "https://orcid.org/0000-0001-5208-3432" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "fibroblast neural crest derived" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000006", "lbl" : "neuronal receptor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any sensory receptor cell that is a(n) neuron and is capable of some detection of stimulus involved in sensory perception.", "xrefs" : [ "FBC:Autogenerated" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neuronal receptor cell (sensu Animalia)" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000007", "lbl" : "early embryonic cell (metazoa)", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell found in the embryo before the formation of all the gem layers is complete.", "xrefs" : [ "GOC:tfm" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000008", "lbl" : "migratory cranial neural crest cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination.", "xrefs" : [ "ZFA:0007091", "https://orcid.org/0000-0001-5208-3432" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000011", "lbl" : "migratory trunk neural crest cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination.", "xrefs" : [ "ZFA:0007095", "https://orcid.org/0000-0001-5208-3432" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000014", "lbl" : "germ line stem cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A stem cell that is the precursor of gametes.", "xrefs" : [ "doi:10.1016/j.stem.2012.05.016" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "germline stem cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000021", "lbl" : "female germ cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Female germ cell is a germ cell that supports female gamete production.", "xrefs" : [ "GOC:tfm", "PMID:11023867", "PMID:20454446" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "MA:0000388" }, { "val" : "VHOG:0001530" }, { "val" : "ncithesaurus:Egg" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000022", "lbl" : "female germ line stem cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A stem cell that is the precursor of female gametes.", "xrefs" : [ "doi:10.1016/j.stem.2012.05.016" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000023", "lbl" : "oocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "A female germ cell that has entered meiosis.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "oogonium" } ], "xrefs" : [ { "val" : "BTO:0000964" }, { "val" : "CALOHA:TS-0711" }, { "val" : "FMA:18644" }, { "val" : "MESH:D009865" }, { "val" : "WBbt:0006797" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000024", "lbl" : "oogonial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "FMA:83673" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000025", "lbl" : "egg cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mature oocyte" }, { "pred" : "hasExactSynonym", "val" : "ovum" } ], "xrefs" : [ { "val" : "BTO:0000369" }, { "val" : "BTO:0003801" }, { "val" : "CALOHA:TS-2191" }, { "val" : "FMA:67343" }, { "val" : "MESH:D010063" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000027", "lbl" : "smooth muscle cell neural crest derived", "type" : "CLASS", "meta" : { "definition" : { "val" : "A smooth muscle cell derived from the neural crest.", "xrefs" : [ "https://orcid.org/0000-0001-5208-3432" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000029", "lbl" : "neural crest derived neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any neuron that develops from some migratory neural crest cell.", "xrefs" : [ "FBC:Autogenerated" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neuron neural crest derived" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000030", "lbl" : "glioblast", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000031", "lbl" : "neuroblast (sensu Vertebrata)", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell that will develop into a neuron often after a migration phase.", "xrefs" : [ "GOC:NV", "http://en.wikipedia.org/wiki/Neuroblast" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neuroblast" } ], "xrefs" : [ { "val" : "BTO:0000930" }, { "val" : "FMA:70563" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000034", "lbl" : "stem cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.", "xrefs" : [ "GOC:tfm", "MESH:D013234" ] }, "comments" : [ "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "animal stem cell" } ], "xrefs" : [ { "val" : "CALOHA:TS-2086" }, { "val" : "FMA:63368" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000035", "lbl" : "single fate stem cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A stem cell that self-renews as well as give rise to a single mature cell type.", "xrefs" : [ "GOC:tfm" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "unipotent stem cell" }, { "pred" : "hasExactSynonym", "val" : "unipotential stem cell" } ], "xrefs" : [ { "val" : "FMA:70569" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000037", "lbl" : "hematopoietic stem cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119.", "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "PMID:19022770", "http://en.wikipedia.org/wiki/Hematopoietic_stem_cell" ] }, "comments" : [ "Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "blood forming stem cell" }, { "pred" : "hasExactSynonym", "val" : "hemopoietic stem cell" }, { "pred" : "hasRelatedSynonym", "val" : "colony forming unit hematopoietic" } ], "xrefs" : [ { "val" : "BTO:0000725" }, { "val" : "CALOHA:TS-0448" }, { "val" : "FMA:86475" }, { "val" : "MESH:D006412" }, { "val" : "VHOG:0001485" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000038", "lbl" : "erythroid progenitor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A progenitor cell committed to the erythroid lineage.", "xrefs" : [ "GOC:add", "ISBN:0721601464" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "blast forming unit erythroid" }, { "pred" : "hasRelatedSynonym", "val" : "burst forming unit erythroid" }, { "pred" : "hasRelatedSynonym", "val" : "colony forming unit erythroid" }, { "pred" : "hasRelatedSynonym", "val" : "erythroid stem cell" } ], "xrefs" : [ { "val" : "BTO:0004911" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000039", "lbl" : "germ line cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, "comments" : [ "Originally this term had some plant germ line cell children." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/ubprop#_upper_level" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000048", "lbl" : "multi fate stem cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A stem cell that can give rise to multiple lineages of cells.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "multi-fate stem cell" }, { "pred" : "hasExactSynonym", "val" : "multifate stem cell" }, { "pred" : "hasExactSynonym", "val" : "multipotent cell" }, { "pred" : "hasExactSynonym", "val" : "multipotent stem cell" } ], "xrefs" : [ { "val" : "FMA:84789" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000049", "lbl" : "common myeloid progenitor", "type" : "CLASS", "meta" : { "definition" : { "val" : "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages.", "xrefs" : [ "GOC:add", "ISBN:0878932437", "MESH:D023461" ] }, "comments" : [ "This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059)." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "common myeloid precursor" }, { "pred" : "hasRelatedSynonym", "val" : "colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte", "xrefs" : [ "ISBN:0878932437" ] }, { "pred" : "hasRelatedSynonym", "val" : "multipotential myeloid stem cell", "xrefs" : [ "ISBN:0878932437" ] }, { "pred" : "hasRelatedSynonym", "val" : "myeloid stem cell", "xrefs" : [ "ISBN:0878932437" ] }, { "pred" : "hasRelatedSynonym", "val" : "pluripotent stem cell (bone marrow)", "xrefs" : [ "ISBN:0878932437" ] } ], "xrefs" : [ { "val" : "BTO:0004730" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000050", "lbl" : "megakaryocyte-erythroid progenitor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A progenitor cell committed to the megakaryocyte and erythroid lineages.", "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "MESH:D055015", "PMID:16647566", "http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell" ] }, "comments" : [ "MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CFU-EM" }, { "pred" : "hasExactSynonym", "val" : "CFU-MegE" }, { "pred" : "hasExactSynonym", "val" : "MEP" }, { "pred" : "hasExactSynonym", "val" : "Meg/E progenitor" }, { "pred" : "hasExactSynonym", "val" : "colony forming unit erythroid megakaryocyte" }, { "pred" : "hasExactSynonym", "val" : "megakaryocyte/erythrocyte progenitor" }, { "pred" : "hasExactSynonym", "val" : "megakaryocyte/erythroid progenitor cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000051", "lbl" : "common lymphoid progenitor", "type" : "CLASS", "meta" : { "definition" : { "val" : "A oligopotent progenitor cell committed to the lymphoid lineage.", "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "PMID:10407577", "PMID:16551251" ] }, "comments" : [ "CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "common lymphocyte precursor" }, { "pred" : "hasExactSynonym", "val" : "common lymphocyte progenitor" }, { "pred" : "hasExactSynonym", "val" : "common lymphoid precursor" }, { "pred" : "hasRelatedSynonym", "val" : "committed lymphopoietic stem cell" }, { "pred" : "hasRelatedSynonym", "val" : "early lymphocyte progenitor" }, { "pred" : "hasRelatedSynonym", "val" : "lymphoid stem cell" }, { "pred" : "hasRelatedSynonym", "val" : "lymphopoietic stem cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000052", "lbl" : "totipotent stem cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A stem cell from which all cells of the body can form.", "xrefs" : [ "GOC:add", "GOC:tfm" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "totipotential stem cell" } ], "xrefs" : [ { "val" : "FMA:84790" }, { "val" : "MESH:D039901" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000055", "lbl" : "non-terminally differentiated cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A precursor cell with a limited number of potential fates.", "xrefs" : [ "SANBI:mhl" ] }, "comments" : [ "define using PATO mulit-potent or oligopotent?" ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "blast cell" } ], "xrefs" : [ { "val" : "BTO:0000125" }, { "val" : "FMA:84782" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000056", "lbl" : "myoblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair.", "xrefs" : [ "GOC:tfm", "MESH:D032446", "PMID:21849021" ] }, "xrefs" : [ { "val" : "BTO:0000222" }, { "val" : "CALOHA:TS-0650" }, { "val" : "FMA:70335" }, { "val" : "VHOG:0001529" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000057", "lbl" : "fibroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.", "xrefs" : [ "ISBN:0517223651", "MESH:D005347", "http://en.wikipedia.org/wiki/Fibroblast" ] }, "comments" : [ "These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0000452" }, { "val" : "CALOHA:TS-0362" }, { "val" : "FMA:63877" }, { "val" : "NCIT:C12482" }, { "val" : "VHOG:0001482" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000058", "lbl" : "chondroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell.", "xrefs" : [ "GOC:tfm", "GO_REF:0000034", "ISBN:0618947256" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "chrondoplast" } ], "xrefs" : [ { "val" : "BTO:0003607" }, { "val" : "FMA:66783" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000064", "lbl" : "ciliated cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell that has a filiform extrusion of the cell surface.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "VHOG:0001532" }, { "val" : "XAO:0000031" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000066", "lbl" : "epithelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.", "xrefs" : [ "FB:ma", "GOC:tfm", "MESH:D004847" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epitheliocyte" } ], "xrefs" : [ { "val" : "BTO:0000414" }, { "val" : "CALOHA:TS-2026" }, { "val" : "CARO:0000077" }, { "val" : "FMA:66768" }, { "val" : "WBbt:0003672" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000067", "lbl" : "ciliated epithelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An epithelial cell that has a cilia.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "FMA:70605" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000068", "lbl" : "duct epithelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An epithelial cell that is part of a duct.", "xrefs" : [ "https://orcid.org/0000-0001-5208-3432" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000071", "lbl" : "blood vessel endothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An endothelial cell that lines the vasculature.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000075", "lbl" : "columnar/cuboidal epithelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.", "xrefs" : [ "GO:0002065", "https://orcid.org/0000-0001-5208-3432" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000076", "lbl" : "squamous epithelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any epithelial cell that is part of some squamous epithelium.", "xrefs" : [ "FBC:Autogenerated" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-1249" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000077", "lbl" : "mesothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A flat, squamous-like epithelial cell of mesodermal origin. It forms the mesothelium, which lines the body's serous cavities including the pleural, peritoneal, and pericardial spaces. This cell plays a crucial role in synthesizing and secreting lubricants, such as glycosaminoglycans and surfactants, which minimize friction between adjacent tissues during movement.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544", "PMID:26106328" ] }, "comments" : [ "Mesothelial cells, which morphologically resemble squamous epithelial cells, express both epithelial markers (cytokeratins) and mesenchymal markers (vimentin), reflecting their mesodermal origin. They feature surface microvilli and apical-basal polarity. Under certain conditions, they can undergo mesothelial-to-mesenchymal transition. These cells also produce extracellular matrix proteins, maintain serosal homeostasis, and facilitate fluid transport." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesotheliocyte" } ], "xrefs" : [ { "val" : "FMA:66773" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000080", "lbl" : "circulating cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell which moves among different tissues of the body, via blood, lymph, or other medium.", "xrefs" : [ "GOC:add" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000081", "lbl" : "blood cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell found predominately in the blood.", "xrefs" : [ "GOC:add", "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], "xrefs" : [ { "val" : "FMA:62844" }, { "val" : "MESH:D001773" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000082", "lbl" : "epithelial cell of lung", "type" : "CLASS", "meta" : { "definition" : { "val" : "An epithelial cell of the lung.", "xrefs" : [ "https://orcid.org/0000-0001-5208-3432" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "lung epithelial cell" } ], "xrefs" : [ { "val" : "BTO:0004299" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000095", "lbl" : "neuron associated cell", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000098", "lbl" : "sensory epithelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells.", "xrefs" : [ "GOC:tfm", "ISBN:0517223651", "ISBN:0721662544" ] }, "comments" : [ "The term \"neuroepithelial cell\" is used to describe both this cell type and neurecto-epithelial cell (CL:0000710)." ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "neuroepithelial cell" } ], "xrefs" : [ { "val" : "BTO:0004301" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000099", "lbl" : "interneuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions.", "xrefs" : [ "GOC:tfm", "MESH:D007395" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0003811" }, { "val" : "FMA:67313" }, { "val" : "WBbt:0005113" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000100", "lbl" : "motor neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement.", "xrefs" : [ "MESH:D009046", "PMID:16875686" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "motoneuron" } ], "xrefs" : [ { "val" : "BTO:0000312" }, { "val" : "FMA:83617" }, { "val" : "WBbt:0005409" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000101", "lbl" : "sensory neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any neuron having a sensory function; an afferent neuron conveying sensory impulses.", "xrefs" : [ "ISBN:0721662544" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0001037" }, { "val" : "FMA:84649" }, { "val" : "MESH:D011984" }, { "val" : "WBbt:0005759" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000103", "lbl" : "bipolar neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body.", "xrefs" : [ "GOC:tfm", "ISBN:0444009442" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#BDS_subset", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "FMA:67282" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000104", "lbl" : "multipolar neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuron with three or more neurites, usually an axon and multiple dendrites.", "xrefs" : [ "FMA:67287", "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#BDS_subset" ], "xrefs" : [ { "val" : "FMA:67287" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000107", "lbl" : "autonomic neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuron whose cell body is within an autonomic ganglion.", "xrefs" : [ "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:80121" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000108", "lbl" : "cholinergic neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuron that uses acetylcholine as a vesicular neurotransmitter.", "xrefs" : [ "GOC:tfm" ] }, "xrefs" : [ { "val" : "BTO:0004902" }, { "val" : "FMA:84796" }, { "val" : "MESH:D059329" }, { "val" : "WBbt:0006840" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000115", "lbl" : "endothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm.", "xrefs" : [ "GOC:tfm", "MESH:D042783", "PMID:21275341", "http://en.wikipedia.org/wiki/Endothelial_cell", "https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855" ] }, "comments" : [ "From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "endotheliocyte" } ], "xrefs" : [ { "val" : "BTO:0001176" }, { "val" : "CALOHA:TS-0278" }, { "val" : "FMA:66772" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000117", "lbl" : "CNS neuron (sensu Vertebrata)", "type" : "CLASS" }, { "id" : "http://purl.obolibrary.org/obo/CL_0000122", "lbl" : "stellate neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuron that has dendritic processes radiating from the cell body forming a star-like shape.", "xrefs" : [ "ISBN:9780123973481" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#BDS_subset", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0002316" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000123", "lbl" : "neuron associated cell (sensu Vertebrata)", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000125", "lbl" : "glial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons.", "xrefs" : [ "MESH:D009457" ] }, "comments" : [ "Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571" ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neuroglial cell" }, { "pred" : "hasRelatedSynonym", "val" : "neuroglia" } ], "xrefs" : [ { "val" : "BTO:0002606" }, { "val" : "CALOHA:TS-0415" }, { "val" : "FMA:54536" }, { "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000125" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000126", "lbl" : "macroglial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "macrogliocyte" } ], "xrefs" : [ { "val" : "BTO:0000771" }, { "val" : "CALOHA:TS-2027" }, { "val" : "FMA:54538" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000128", "lbl" : "oligodendrocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system.", "xrefs" : [ "MESH:D009836", "http://en.wikipedia.org/wiki/Oligodendrocyte" ] }, "comments" : [ "Oligodendrocytes are reportedly MDP-positive and CD4-negative." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "OLs", "xrefs" : [ "PMID:8734446" ] }, { "pred" : "hasRelatedSynonym", "val" : "oligodendroglia" } ], "xrefs" : [ { "val" : "BTO:0000962" }, { "val" : "CALOHA:TS-0709" }, { "val" : "FMA:54540" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000133", "lbl" : "neurectodermal cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Ectoderm destined to be nervous tissue.", "xrefs" : [ "GOC:tfm", "ISBN:068340007X" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neurectoderm cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000134", "lbl" : "mesenchymal stem cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs.", "xrefs" : [ "FB:ma", "GOC:dsd", "PMCID:PMC2613570", "PMID:10102814", "PMID:16923606", "PMID:17986482", "PMID:19960544", "http://en.wikipedia.org/wiki/Mesenchymal_stem_cell", "http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells" ] }, "comments" : [ "Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "bone marrow stromal cells" }, { "pred" : "hasNarrowSynonym", "val" : "colony-forming unit-fibroblast" }, { "pred" : "hasNarrowSynonym", "val" : "marrow stromal cells", "xrefs" : [ "PMID:11378515" ] }, { "pred" : "hasRelatedSynonym", "val" : "mesenchymal precursor cell" }, { "pred" : "hasRelatedSynonym", "val" : "mesenchymal stem cell" }, { "pred" : "hasRelatedSynonym", "val" : "mesenchymal stromal cell" } ], "xrefs" : [ { "val" : "BTO:0002625" }, { "val" : "BTO:0003298" }, { "val" : "FMA:70546" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000136", "lbl" : "adipocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides.", "xrefs" : [ "MESH:D017667" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "adipose cell" }, { "pred" : "hasExactSynonym", "val" : "fat cell" } ], "xrefs" : [ { "val" : "BTO:0000443" }, { "val" : "CALOHA:TS-0012" }, { "val" : "FMA:63880" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000138", "lbl" : "chondrocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "Skeletogenic cell that is terminally differentiated, secretes an avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell.", "xrefs" : [ "GO_REF:0000034", "MESH:D019902" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cartilage cell" } ], "xrefs" : [ { "val" : "BTO:0000249" }, { "val" : "CALOHA:TS-0138" }, { "val" : "FMA:66782" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000147", "lbl" : "pigment cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A pigment cell is a cell that contains pigment granules.", "xrefs" : [ "GOC:tfm" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "chromatocyte" }, { "pred" : "hasExactSynonym", "val" : "chromatophore" } ], "xrefs" : [ { "val" : "VHOG:0001678" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000149", "lbl" : "visual pigment cell", "type" : "CLASS", "meta" : { "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "pigment cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000150", "lbl" : "glandular epithelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-2085" }, { "val" : "FMA:86494" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000151", "lbl" : "secretory cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell that specializes in controlled release of one or more substances.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0003659" }, { "val" : "FMA:86916" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000152", "lbl" : "exocrine cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct.", "xrefs" : [ "ISBN:0198547684" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], "xrefs" : [ { "val" : "FMA:16014" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000153", "lbl" : "glycosaminoglycan secreting cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell that secretes glycosaminoglycans.", "xrefs" : [ "GOC:tfm" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "GAG secreting cell" }, { "pred" : "hasNarrowSynonym", "val" : "hyaluronic acid secreting cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000154", "lbl" : "protein secreting cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any secretory cell that is capable of some protein secretion.", "xrefs" : [ "FBC:Autogenerated" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000159", "lbl" : "seromucus secreting cell", "type" : "CLASS" }, { "id" : "http://purl.obolibrary.org/obo/CL_0000163", "lbl" : "endocrine cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions.", "xrefs" : [ "MESH:D055098" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "endocrinocyte" } ], "xrefs" : [ { "val" : "FMA:83809" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000164", "lbl" : "enteroendocrine cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas.", "xrefs" : [ "GOC:tfm", "SANBI:mhl" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0003865" }, { "val" : "FMA:62930" }, { "val" : "MESH:D019858" }, { "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000164" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000165", "lbl" : "neuroendocrine cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuron that is capable of some hormone secretion in response to neuronal signals.", "xrefs" : [ "MESH:D055099" ] }, "comments" : [ "The neurosecretory cell is neither an ordinary neuron nor an endocrine cell, but a combination of both. Its neuronal features resemble those of ordinary neurons concerning both structure and function. The production of a visible secretory material marks the neurosecretory neuron as a gland cell, and the fact that extractable cellular products act in the manner of hormones places it in the realm of endocrine elements. \n\nThe modern definition of neurosecretion has evolved to include the release of any neuronal secretory product from a neuron." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "neurosecretory cell" }, { "pred" : "hasRelatedSynonym", "val" : "neurosecretory neuron" } ], "xrefs" : [ { "val" : "BTO:0002691" }, { "val" : "FMA:83810" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000167", "lbl" : "peptide hormone secreting cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any secretory cell that is capable of some peptide hormone secretion.", "xrefs" : [ "FBC:Autogenerated" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000170", "lbl" : "glucagon secreting cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell that secretes glucagon.", "xrefs" : [ "GOC:tfm" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "glucagon-secreting cell" } ], "xrefs" : [ { "val" : "FMA:84045" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000172", "lbl" : "somatostatin secreting cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any secretory cell that is capable of some somatostatin secretion.", "xrefs" : [ "FBC:Autogenerated" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000174", "lbl" : "steroid hormone secreting cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any secretory cell that is capable of some steroid hormone secretion.", "xrefs" : [ "FBC:Autogenerated" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000183", "lbl" : "contractile cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell whose primary function is to shorten.", "xrefs" : [ "FB:ma" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000187", "lbl" : "muscle cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.", "xrefs" : [ "MESH:D032342" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "muscle fiber" }, { "pred" : "hasExactSynonym", "val" : "myocyte" } ], "xrefs" : [ { "val" : "BTO:0000888" }, { "val" : "BTO:0000902" }, { "val" : "CALOHA:TS-2032" }, { "val" : "FMA:67328" }, { "val" : "WBbt:0003675" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000188", "lbl" : "cell of skeletal muscle", "type" : "CLASS", "meta" : { "definition" : { "val" : "A somatic cell located in skeletal muscle.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "skeletal muscle cell" } ], "xrefs" : [ { "val" : "BTO:0004392" }, { "val" : "CALOHA:TS-2158" }, { "val" : "FMA:9727" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000192", "lbl" : "smooth muscle cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast).", "xrefs" : [ "MESH:D032389", "PMID:9315361", "http://en.wikipedia.org/wiki/Smooth_muscle_cell" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "non-striated muscle cell" }, { "pred" : "hasExactSynonym", "val" : "SMCs", "xrefs" : [ "PMID:9315361" ] }, { "pred" : "hasExactSynonym", "val" : "myocytes, smooth muscle", "xrefs" : [ "MESH:D032389" ] }, { "pred" : "hasExactSynonym", "val" : "smooth muscle fiber" } ], "xrefs" : [ { "val" : "BTO:0004576" }, { "val" : "CALOHA:TS-2159" }, { "val" : "FMA:14072" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000197", "lbl" : "sensory receptor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell that is capable of detection of a stimulus involved in sensory perception." }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "receptor cell" } ], "xrefs" : [ { "val" : "MESH:D011984" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000206", "lbl" : "chemoreceptor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood.", "xrefs" : [ "MESH:D002628" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000209", "lbl" : "taste receptor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A specialized cell involved in gustatory sensory perception.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "taste bud cell" } ], "xrefs" : [ { "val" : "FMA:67910" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000210", "lbl" : "photoreceptor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell specialized in detecting light stimuli that are involved in visual perception.", "xrefs" : [ "MESH:D010786" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001060" }, { "val" : "CALOHA:TS-0868" }, { "val" : "FMA:86740" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000211", "lbl" : "electrically active cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell whose function is determined by the generation or the reception of an electric signal.", "xrefs" : [ "FB:ma" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000213", "lbl" : "lining cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism.", "xrefs" : [ "JB:jb" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "boundary cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000214", "lbl" : "synovial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell located in the synovial joint." }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "synoviocyte" } ], "xrefs" : [ { "val" : "CALOHA:TS-0995" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000215", "lbl" : "barrier cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell whose primary function is to prevent the transport of stuff across compartments.", "xrefs" : [ "JB:jb" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000217", "lbl" : "insulating cell", "type" : "CLASS" }, { "id" : "http://purl.obolibrary.org/obo/CL_0000218", "lbl" : "myelinating Schwann cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuroglial cell of the peripheral nervous system which forms the insulating myelin sheaths of peripheral axons.", "xrefs" : [ "GOC:cvs", "GOC:tfm", "MESH:D012583" ] }, "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "Schwann cell" }, { "pred" : "hasBroadSynonym", "val" : "peripheral neuroglial cell" }, { "pred" : "hasExactSynonym", "val" : "neurilemmal cell" } ], "xrefs" : [ { "val" : "CALOHA:TS-0898" }, { "val" : "FMA:62121" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000219", "lbl" : "motile cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell that moves by its own activities.", "xrefs" : [ "FB:ma" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000221", "lbl" : "ectodermal cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell of the outer of the three germ layers of the embryo.", "xrefs" : [ "MESH:D004475" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "ectoderm cell" } ], "xrefs" : [ { "val" : "FMA:72549" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000222", "lbl" : "mesodermal cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell of the middle germ layer of the embryo.", "xrefs" : [ "MESH:D008648" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesoblast" }, { "pred" : "hasExactSynonym", "val" : "mesoderm cell" } ], "xrefs" : [ { "val" : "FMA:72554" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000223", "lbl" : "endodermal cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell of the inner of the three germ layers of the embryo.", "xrefs" : [ "MESH:D004707" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "endoderm cell" } ], "xrefs" : [ { "val" : "FMA:72555" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000225", "lbl" : "anucleate cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell that lacks a nucleus.", "xrefs" : [ "FB:ma" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "non-nucleated cell" } ], "xrefs" : [ { "val" : "FMA:68647" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000226", "lbl" : "single nucleate cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell with a single nucleus.", "xrefs" : [ "FB:ma", "GOC:tfm" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000227", "lbl" : "binucleate cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any cell that has characteristic some binucleate.", "xrefs" : [ "FBC:Autogenerated" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000228", "lbl" : "multinucleate cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell with more than one nucleus.", "xrefs" : [ "FB:ma", "Wikipedia:Multinucleate" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "multinucleated cells", "xrefs" : [ "Wikipedia:Multinucleate" ] }, { "pred" : "hasExactSynonym", "val" : "polynuclear cells", "xrefs" : [ "Wikipedia:Multinucleate" ] } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000232", "lbl" : "erythrocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.", "xrefs" : [ "GOC:tfm", "MESH:D004912" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "RBC" }, { "pred" : "hasExactSynonym", "val" : "red blood cell" } ], "xrefs" : [ { "val" : "BTO:0000424" }, { "val" : "CALOHA:TS-0290" }, { "val" : "FMA:81100" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000255", "lbl" : "eukaryotic cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any cell that in taxon some Eukaryota.", "xrefs" : [ "FBC:Autogenerated" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "MESH:D005057" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000257", "lbl" : "Eumycetozoan cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any cell that in taxon some Eumycetozoa.", "xrefs" : [ "FBC:Autogenerated" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000287", "lbl" : "eye photoreceptor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any photoreceptor cell that is part of some eye.", "xrefs" : [ "FBC:Autogenerated" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000293", "lbl" : "structural cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell whose primary function is to provide structural support, to provide strength and physical integrity to the organism.", "xrefs" : [ "TAIR:sr" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000300", "lbl" : "gamete", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mature sexual reproductive cell having a single set of unpaired chromosomes.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "haploid nucleated cell" }, { "pred" : "hasRelatedSynonym", "val" : "haploid germ cell" } ], "xrefs" : [ { "val" : "CALOHA:TS-0395" }, { "val" : "FMA:18649" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000306", "lbl" : "crystallin accumulating cell", "type" : "CLASS", "meta" : { "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "lens cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000313", "lbl" : "serous secreting cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid.", "xrefs" : [ "GOC:tfm", "ISBN:0517223651", "ISBN:0721662544" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "serous cell" } ], "xrefs" : [ { "val" : "BTO:0003687" }, { "val" : "FMA:62511" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000325", "lbl" : "stuff accumulating cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell that is specialised to accumulate a particular substance(s).", "xrefs" : [ "FB:ma" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/ubprop#_upper_level" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000327", "lbl" : "extracellular matrix secreting cell", "type" : "CLASS" }, { "id" : "http://purl.obolibrary.org/obo/CL_0000329", "lbl" : "oxygen accumulating cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any cell that is capable of some oxygen transport.", "xrefs" : [ "FBC:Autogenerated" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000333", "lbl" : "migratory neural crest cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body.", "xrefs" : [ "doi:10.1016/j.stem.2015.02.017" ] }, "xrefs" : [ { "val" : "FMA:86667" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000335", "lbl" : "mesenchyme condensation cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors.", "xrefs" : [ "GOC:tfm", "PMID:5025404" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000339", "lbl" : "glioblast (sensu Vertebrata)", "type" : "CLASS", "meta" : { "definition" : { "val" : "An early neural cell developing from the early ependymal cell of the neural tube.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "spongioblast" } ], "xrefs" : [ { "val" : "FMA:70564" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000347", "lbl" : "scleral cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell of the sclera of the eye.", "xrefs" : [ "GOC:add" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000348", "lbl" : "choroidal cell of the eye", "type" : "CLASS", "meta" : { "definition" : { "val" : "A structural cell that is part of optic choroid.", "xrefs" : [ "GOC:add" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000349", "lbl" : "extraembryonic cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any cell that is part of some extraembryonic structure.", "xrefs" : [ "FBC:Autogenerated" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000351", "lbl" : "trophoblast cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An extraembryonic cell that develops from a trophectodermal cell. This cell is found in the outer layer of the blastocyst and can invade other structures in the uterus once the blastocyst implants into the uterine wall. A trophoblast cell is involved in the implantation of the embryo into the uterine wall, placental formation, remodelling of maternal vasculature in the uterus, nutrient and gas exchange, hormone production, and immune modulation to support fetal development.", "xrefs" : [ "GOC:tfm", "MESH:D014327", "PMID:37630754", "doi:10.1007/978-3-030-84725-8" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "trophoblastic cell", "xrefs" : [ "doi:10.1007/978-3-030-84725-8" ] } ], "xrefs" : [ { "val" : "FMA:83028" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000352", "lbl" : "epiblast cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000353", "lbl" : "blastoderm cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An undifferentiated cell produced by early cleavages of the fertilized egg (zygote).", "xrefs" : [ "MESH:D001756" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "blastomere" } ], "xrefs" : [ { "val" : "BTO:0001473" }, { "val" : "FMA:72551" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000355", "lbl" : "multi-potent skeletal muscle stem cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell.", "xrefs" : [ "PMID:18282570" ] }, "comments" : [ "Multi-potency demonstrated ex vivo. At the time of writing, it is unclear whether the endogenous population differentiates into multiple cell types in vivo." ], "xrefs" : [ { "val" : "FMA:86767" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000359", "lbl" : "vascular associated smooth muscle cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A smooth muscle cell associated with the vasculature.", "xrefs" : [ "GOC:dsd", "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "VSMC" }, { "pred" : "hasExactSynonym", "val" : "vascular smooth muscle cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000362", "lbl" : "epidermal cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An epithelial cell of the integument (the outer layer of an organism).", "xrefs" : [ "Flybase:dsj", "MA:ma" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell of epidermis", "xrefs" : [ "FMA:62411" ] }, { "pred" : "hasNarrowSynonym", "val" : "epithelial cell of skin", "xrefs" : [ "FMA:62411" ] } ], "xrefs" : [ { "val" : "BTO:0001470" }, { "val" : "CALOHA:TS-0283" }, { "val" : "FMA:62411" }, { "val" : "MESH:D000078404" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000365", "lbl" : "animal zygote", "type" : "CLASS", "meta" : { "definition" : { "val" : "Diploid cell produced by the fusion of sperm cell nucleus and egg cell.", "xrefs" : [ "ISBN:0471245208" ] }, "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "zygote" } ], "xrefs" : [ { "val" : "BTO:0000854" }, { "val" : "EHDAA2:0004546" }, { "val" : "FMA:72395" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000393", "lbl" : "electrically responsive cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell whose function is determined by its response to an electric signal.", "xrefs" : [ "FB:ma" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000397", "lbl" : "ganglion interneuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any interneuron that has its soma located in some ganglion.", "xrefs" : [ "FBC:Autogenerated" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000402", "lbl" : "CNS interneuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "An interneuron that has its cell body in a central nervous system.", "xrefs" : [ "doi:10.1016/B978-0-12-817424-1.00001-X" ] }, "comments" : [ "Interneurons are commonly described as being only found in the central nervous system. However, in CL we define 'interneuron' more broadly as any neuron that is neither a motor neuron nor a sensory neuron, regardless of its location, so we need this term to refer strictly to interneurons of the central nervous system." ], "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000404", "lbl" : "electrically signaling cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell that initiates an electrical signal and passes that signal to another cell.", "xrefs" : [ "FB:ma" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000412", "lbl" : "polyploid cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell that contains more than two haploid sets of chromosomes.", "xrefs" : [ "FB:ma", "PMID:32646579", "https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/07%3A_Cell_Division/7.04%3A_Polyploidy" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000413", "lbl" : "haploid cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell whose nucleus contains a single haploid genome.", "xrefs" : [ "FB:ma", "GOC:tfm" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000444", "lbl" : "obliquely striated muscle cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A muscle cell in which the fibers are organised into sarcomeres but in which adjacent myofibrils are offset from each other, producing an oblique banding pattern.", "xrefs" : [ "GOC:DOS", "PMID:8720463" ] }, "comments" : [ "Examples include the somatic muscles of nemotodes and cephalopods." ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000447", "lbl" : "carbohydrate secreting cell", "type" : "CLASS" }, { "id" : "http://purl.obolibrary.org/obo/CL_0000457", "lbl" : "biogenic amine secreting cell", "type" : "CLASS" }, { "id" : "http://purl.obolibrary.org/obo/CL_0000458", "lbl" : "serotonin secreting cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell type that secretes 5-Hydroxytryptamine (serotonin).", "xrefs" : [ "GOC:tfm", "PMID:19630576" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "5-HT secreting cell" }, { "pred" : "hasExactSynonym", "val" : "5-Hydroxytryptamine secreting cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000459", "lbl" : "noradrenergic cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme.", "xrefs" : [ "GOC:tfm", "ISBN:068340007X" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "noradrenaline secreting cell" }, { "pred" : "hasExactSynonym", "val" : "norepinephrin secreting cell" }, { "pred" : "hasExactSynonym", "val" : "norepinephrine secreting cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000488", "lbl" : "visible light photoreceptor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A photoreceptor cell that detects visible light.", "xrefs" : [ "GOC:tfm" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000499", "lbl" : "stromal cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere.", "xrefs" : [ "GOC:tfm", "MESH:D017154" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0002064" }, { "val" : "FMA:83624" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000513", "lbl" : "cardiac muscle myoblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "A precursor cell destined to differentiate into cardiac muscle cell.", "xrefs" : [ "GOC:tfm", "MESH:D032386" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cardiac muscle progenitor cell" }, { "pred" : "hasExactSynonym", "val" : "cardiomyocyte progenitor cell" } ], "xrefs" : [ { "val" : "FMA:84797" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000514", "lbl" : "smooth muscle myoblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "A precursor cell destined to differentiate into smooth muscle myocytes.", "xrefs" : [ "GOC:tfm", "MESH:D032390" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "myoblast, smooth muscle", "xrefs" : [ "MESH:D032390" ] }, { "pred" : "hasRelatedSynonym", "val" : "satellite cell" } ], "xrefs" : [ { "val" : "FMA:84798" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000515", "lbl" : "skeletal muscle myoblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "A myoblast that differentiates into skeletal muscle fibers.", "xrefs" : [ "SANBI:mhl" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "skeletal myoblast" } ], "xrefs" : [ { "val" : "FMA:84799" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000521", "lbl" : "fungal cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any cell that in taxon some Fungi.", "xrefs" : [ "FBC:Autogenerated" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000525", "lbl" : "syncytiotrophoblast cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy.", "xrefs" : [ "GOC:tfm", "ISBN:0323052908" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "syncytial trophoblast cell", "xrefs" : [ "PMID:11787150" ] }, { "pred" : "hasExactSynonym", "val" : "syncytiotrophoblastic cell", "xrefs" : [ "PMID:21733368" ] }, { "pred" : "hasRelatedSynonym", "val" : "plasmidotrophoblast cell" }, { "pred" : "hasRelatedSynonym", "val" : "syntrophoblast cell" } ], "xrefs" : [ { "val" : "FMA:83043" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000526", "lbl" : "afferent neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuron which conveys sensory information centrally from the periphery.", "xrefs" : [ "GOC:tfm", "MESH:D009475" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "input neuron" } ], "xrefs" : [ { "val" : "FMA:87653" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000527", "lbl" : "efferent neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuron which sends impulses peripherally to activate muscles or secretory cells.", "xrefs" : [ "MESH:D009476" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "output neuron" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000540", "lbl" : "neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.", "xrefs" : [ "MESH:D009474", "http://en.wikipedia.org/wiki/Neuron" ] }, "comments" : [ "These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "nerve cell" } ], "xrefs" : [ { "val" : "BTO:0000938" }, { "val" : "CALOHA:TS-0683" }, { "val" : "FMA:54527" }, { "val" : "VHOG:0001483" }, { "val" : "WBbt:0003679" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000542", "lbl" : "lymphocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.", "xrefs" : [ "GOC:add", "ISBN:0683073696", "ISBN:0781735149" ] }, "comments" : [ "Editors note: consider adding taxon constraint to vertebrata (PMID:18025161)" ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0000775" }, { "val" : "CALOHA:TS-0583" }, { "val" : "FMA:62863" }, { "val" : "MESH:D008214" }, { "val" : "VHOG:0001535" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000547", "lbl" : "proerythroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers.", "xrefs" : [ "ISBN:0721601464", "PMID:1638021" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "rubriblast", "xrefs" : [ "ISBN:0721601464" ] }, { "pred" : "hasRelatedSynonym", "val" : "pronormoblast" } ], "xrefs" : [ { "val" : "FMA:83518" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000549", "lbl" : "basophilic erythroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers.", "xrefs" : [ "GOC:tfm", "ISBN:0721601464" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "basophilic normoblast", "xrefs" : [ "ISBN:0721601464" ] }, { "pred" : "hasExactSynonym", "val" : "early erythroblast", "xrefs" : [ "ISBN:0721601464" ] }, { "pred" : "hasExactSynonym", "val" : "early normoblast", "xrefs" : [ "ISBN:0721601464" ] }, { "pred" : "hasExactSynonym", "val" : "prorubricyte", "xrefs" : [ "ISBN:0721601464" ] } ], "xrefs" : [ { "val" : "FMA:83505" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000550", "lbl" : "polychromatophilic erythroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers.", "xrefs" : [ "ISBN:0721601464" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "intermediate erythroblast", "xrefs" : [ "ISBN:0721601464" ] }, { "pred" : "hasExactSynonym", "val" : "intermediate normoblast", "xrefs" : [ "ISBN:0721601464" ] }, { "pred" : "hasExactSynonym", "val" : "polychromatic erythroblast", "xrefs" : [ "ISBN:0721601464" ] }, { "pred" : "hasExactSynonym", "val" : "polychromatic normoblast", "xrefs" : [ "ISBN:0721601464" ] }, { "pred" : "hasExactSynonym", "val" : "polychromatophilic normoblast", "xrefs" : [ "ISBN:0721601464" ] }, { "pred" : "hasExactSynonym", "val" : "rubricyte", "xrefs" : [ "ISBN:0721601464" ] } ], "xrefs" : [ { "val" : "FMA:83506" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000552", "lbl" : "orthochromatic erythroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated.", "xrefs" : [ "ISBN:0721601464" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "acidophilic erythroblast", "xrefs" : [ "ISBN:0721601464" ] }, { "pred" : "hasExactSynonym", "val" : "eosinophilic erythroblast", "xrefs" : [ "ISBN:0721601464" ] }, { "pred" : "hasExactSynonym", "val" : "late erythoblast" }, { "pred" : "hasExactSynonym", "val" : "orthochromatic normoblast", "xrefs" : [ "ISBN:0721601464" ] }, { "pred" : "hasExactSynonym", "val" : "pyknotic eto enrythroblast", "xrefs" : [ "ISBN:0721601464" ] } ], "xrefs" : [ { "val" : "FMA:84646" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000553", "lbl" : "megakaryocyte progenitor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative).", "xrefs" : [ "GOC:dsd", "GOC:tfm", "ISBN:0721601464" ] }, "comments" : [ "Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CFU-Meg", "xrefs" : [ "PMID:11722431", "PMID:12482498" ] }, { "pred" : "hasExactSynonym", "val" : "Meg-CFC", "xrefs" : [ "PMCID:PMC1794060" ] }, { "pred" : "hasExactSynonym", "val" : "MkP", "xrefs" : [ "PMID:21116988" ] }, { "pred" : "hasExactSynonym", "val" : "colony-forming unit-megakaryocyte" }, { "pred" : "hasExactSynonym", "val" : "megacaryoblast" }, { "pred" : "hasExactSynonym", "val" : "megacaryocyte progenitor cell" }, { "pred" : "hasExactSynonym", "val" : "megakaryoblast" }, { "pred" : "hasExactSynonym", "val" : "megakaryocytic progenitor cell", "xrefs" : [ "PMID:12482498" ] }, { "pred" : "hasRelatedSynonym", "val" : "promegacaryocyte" }, { "pred" : "hasRelatedSynonym", "val" : "promegakaryocyte" } ], "xrefs" : [ { "val" : "BTO:0001164" }, { "val" : "CALOHA:TS-0610" }, { "val" : "FMA:84235" }, { "val" : "MESH:D055016" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000556", "lbl" : "megakaryocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release.", "xrefs" : [ "ISBN:0721601464", "MESH:D008533", "PMID:31043076", "http://en.wikipedia.org/wiki/Megakaryocyte" ] }, "comments" : [ "Megakaryocytes are reportedly CD181-positive and CD182-positive." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "megacaryocyte" }, { "pred" : "hasExactSynonym", "val" : "megalocaryocyte" }, { "pred" : "hasExactSynonym", "val" : "megalokaryocyte" } ], "xrefs" : [ { "val" : "BTO:0000843" }, { "val" : "CALOHA:TS-0611" }, { "val" : "FMA:83555" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000558", "lbl" : "reticulocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds.", "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:15946868", "PMID:2037622" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001173" }, { "val" : "CALOHA:TS-0864" }, { "val" : "MESH:D012156" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000562", "lbl" : "nucleate erythrocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "An erythrocyte having a nucleus.", "xrefs" : [ "GOC:add", "GOc:tfm" ] }, "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "RBC" }, { "pred" : "hasBroadSynonym", "val" : "red blood cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000566", "lbl" : "angioblastic mesenchymal cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mesenchymal stem cell capable of developing into blood vessel endothelium.", "xrefs" : [ "GOC:dsd", "GOC:tfm", "PMID:12768659" ] }, "comments" : [ "These cells are reportedly CD31-positive, CD34-positive, CD144-positive, CD309-positive, and TAL1-positive." ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "angioblast" }, { "pred" : "hasExactSynonym", "val" : "chondroplast" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000569", "lbl" : "cardiac mesenchymal cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field.", "xrefs" : [ "PMID:18816864" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000573", "lbl" : "retinal cone cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision.", "xrefs" : [ "MESH:D017949" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "cone", "xrefs" : [ "doi:10.1038/s41598-020-66092-9" ] } ], "xrefs" : [ { "val" : "BTO:0001036" }, { "val" : "CALOHA:TS-0866" }, { "val" : "FMA:67748" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000575", "lbl" : "corneal epithelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An epithelial cell of the cornea.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epithelial cell of cornea", "xrefs" : [ "FMA:70551" ] } ], "xrefs" : [ { "val" : "BTO:0004298" }, { "val" : "CALOHA:TS-0173" }, { "val" : "FMA:70551" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000586", "lbl" : "germ cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "The reproductive cell in multicellular organisms.", "xrefs" : [ "MESH:D005854" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0000535" }, { "val" : "NCIT:C12597" }, { "val" : "VHOG:0001534" }, { "val" : "WBbt:0006796" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000593", "lbl" : "androgen secreting cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A steroid hormone secreting cell that secretes androgen.", "xrefs" : [ "GOC:tfm" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000595", "lbl" : "enucleate erythrocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "An erythrocyte lacking a nucleus.", "xrefs" : [ "GOC:add", "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "red blood cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000598", "lbl" : "pyramidal neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "Pyramidal neurons have a pyramid-shaped soma with a single axon, a large apical dendrite and multiple basal dendrites. The apex and an apical dendrite typically point toward the pial surface and other dendrites and an axon emerging from the base. The axons may have local collaterals but also project outside their region. Pyramidal neurons are found in the cerebral cortex, the hippocampus, and the amygdala.", "xrefs" : [ "GOC:tfm", "MESH:D017966" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#BDS_subset", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "projection neuron" }, { "pred" : "hasExactSynonym", "val" : "pyramidal cell" } ], "xrefs" : [ { "val" : "BTO:0003102" }, { "val" : "FMA:67310" }, { "val" : "FMA:86775" }, { "val" : "NIFSTD:sao862606388" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000604", "lbl" : "retinal rod cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision.", "xrefs" : [ "MESH:D017948" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "rod", "xrefs" : [ "doi:10.1038/s41598-020-66092-9" ] } ], "xrefs" : [ { "val" : "BTO:0001024" }, { "val" : "CALOHA:TS-0870" }, { "val" : "FMA:67747" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000630", "lbl" : "supporting cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell whose primary function is to support other cell types.", "xrefs" : [ "FB:ma", "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "supportive cell" } ], "xrefs" : [ { "val" : "BTO:0002315" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000666", "lbl" : "fenestrated endothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An endothelial cell that has small pores, or fenestrations, which allow for the efficient exchange of substances between the blood and surrounding tissues.", "xrefs" : [ "DOI:10.1007/978-3-211-99390-3_133" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "window cell" } ], "xrefs" : [ { "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000666" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000667", "lbl" : "collagen secreting cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An extracellular matrix secreting cell that secretes collagen.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000670", "lbl" : "primordial germ cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells.", "xrefs" : [ "GOC:tfm", "PMID:1381289" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "gonocyte" }, { "pred" : "hasExactSynonym", "val" : "primitive germ cell" } ], "xrefs" : [ { "val" : "FMA:70567" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000675", "lbl" : "female gamete", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mature sexual reproductive cell of the female germline.", "xrefs" : [ "GOC:tfm" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000680", "lbl" : "muscle precursor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A non-terminally differentiated cell that is capable of developing into a muscle cell.", "xrefs" : [ "GOC:add" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000691", "lbl" : "stellate interneuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any interneuron that has characteristic some stellate morphology.", "xrefs" : [ "FBC:Autogenerated" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#BDS_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000693", "lbl" : "neurogliaform cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An interneuron that has spider-like appearance with a small round soma, a large number (7-10) of short, smooth, or slightly beaded primary dendrites that give rise to only a few secondary branches, and a branched axon that establishes a dense axonal mesh with thin shafts.", "xrefs" : [ "JB:jb", "PMID:17122314" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#BDS_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "NGF cell", "xrefs" : [ "PMID:18568015" ] }, { "pred" : "hasExactSynonym", "val" : "neuroglioform cell", "xrefs" : [ "PMID:3235828" ] }, { "pred" : "hasExactSynonym", "val" : "spiderweb cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000696", "lbl" : "PP cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell that stores and secretes pancreatic polypeptide hormone.", "xrefs" : [ "GOC:tfm", "JB:jb", "PMID:15153415" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "type F enteroendocrine cell" } ], "xrefs" : [ { "val" : "FMA:62938" }, { "val" : "FMA:83409" }, { "val" : "https://cellxgene.cziscience.com/cellguide/CL_0000696" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000710", "lbl" : "neurecto-epithelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Epithelial cells derived from neural plate and neural crest.", "xrefs" : [ "GOC:tfm" ] }, "comments" : [ "The term \"neuroepithelial cell\" is used to describe both this cell type and sensory epithelial cell (CL:0000098)." ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "neuroepithelial cell" } ], "xrefs" : [ { "val" : "BTO:0004301" }, { "val" : "FMA:70557" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000723", "lbl" : "somatic stem cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A stem cell that can give rise to cell types of the body other than those of the germ-line.", "xrefs" : [ "GO:0048103" ] }, "xrefs" : [ { "val" : "CALOHA:TS-2086" }, { "val" : "MESH:D053687" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000737", "lbl" : "striated muscle cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Muscle cell which has as its direct parts myofilaments organized into sarcomeres.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, "xrefs" : [ { "val" : "BTO:0002916" }, { "val" : "CALOHA:TS-2157" }, { "val" : "FMA:86936" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000738", "lbl" : "leukocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.", "xrefs" : [ "GOC:add", "GOC:tfm", "ISBN:978-0-323-05290-0" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "leucocyte" }, { "pred" : "hasExactSynonym", "val" : "white blood cell" }, { "pred" : "hasRelatedSynonym", "val" : "immune cell" } ], "xrefs" : [ { "val" : "BTO:0000751" }, { "val" : "CALOHA:TS-0549" }, { "val" : "FMA:62852" }, { "val" : "MESH:D007962" }, { "val" : "NCIT:C12529" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000740", "lbl" : "retinal ganglion cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve.", "xrefs" : [ "GOC:dph" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "gangliocyte" }, { "pred" : "hasExactSynonym", "val" : "ganglion cell of retina" } ], "xrefs" : [ { "val" : "BTO:0001800" }, { "val" : "FMA:67765" }, { "val" : "MESH:D012165" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000746", "lbl" : "cardiac muscle cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei.", "xrefs" : [ "GOC:mtg_cardiacconduct_nov11", "GOC:tfm", "ISBN:0323052908", "PMID:22426062", "PMID:4711263" ] }, "comments" : [ "This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods. The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein). According to these refs, the cells participating in heart contraction in all cases are transversely striated. Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cardiocyte" }, { "pred" : "hasExactSynonym", "val" : "cardiac muscle fiber", "xrefs" : [ "GO:0048739" ] }, { "pred" : "hasExactSynonym", "val" : "cardiac myocyte" }, { "pred" : "hasExactSynonym", "val" : "cardiomyocyte" }, { "pred" : "hasExactSynonym", "val" : "heart muscle cell" } ], "xrefs" : [ { "val" : "BTO:0001539" }, { "val" : "CALOHA:TS-0115" }, { "val" : "FMA:14067" }, { "val" : "MESH:D032383" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "FMA:83808" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000763", "lbl" : "myeloid cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.", "xrefs" : [ "GOC:add" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001441" }, { "val" : "CALOHA:TS-0647" }, { "val" : "MESH:D022423" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000764", "lbl" : "erythroid lineage cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A immature or mature cell in the lineage leading to and including erythrocytes.", "xrefs" : [ "GOC:add", "GOC:tfm" ] }, "comments" : [ "Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "erythropoietic cell" } ], "xrefs" : [ { "val" : "CALOHA:TS-0290" }, { "val" : "FMA:62845" }, { "val" : "FMA:83516" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000765", "lbl" : "erythroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers.", "xrefs" : [ "GOC:add", "ISBN:0721601464", "PMID:18174176" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "normoblast" } ], "xrefs" : [ { "val" : "BTO:0001571" }, { "val" : "CALOHA:TS-0289" }, { "val" : "FMA:83504" }, { "val" : "MESH:D004900" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000766", "lbl" : "myeloid leukocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell of the monocyte, granulocyte, or mast cell lineage.", "xrefs" : [ "GOC:add" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000837", "lbl" : "hematopoietic multipotent progenitor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans.", "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:19022770" ] }, "comments" : [ "Markers differ between mouse and human." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "MPP" }, { "pred" : "hasExactSynonym", "val" : "hemopoietic progenitor cell" } ], "xrefs" : [ { "val" : "BTO:0000725" }, { "val" : "CALOHA:TS-0448" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000838", "lbl" : "lymphoid lineage restricted progenitor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A progenitor cell restricted to the lymphoid lineage.", "xrefs" : [ "GOC:add", "GOC:tfm" ] }, "comments" : [ "Note that this is a class of cell types, not an identified single cell type." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "lymphoid progenitor cell" } ], "xrefs" : [ { "val" : "BTO:0004731" }, { "val" : "CALOHA:TS-2025" }, { "val" : "FMA:70338" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000839", "lbl" : "myeloid lineage restricted progenitor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A progenitor cell restricted to the myeloid lineage.", "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:19022770" ] }, "comments" : [ "Note that this is a class of cell types, not an identified single cell type." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "myeloid progenitor cell" } ], "xrefs" : [ { "val" : "BTO:0004730" }, { "val" : "CALOHA:TS-2099" }, { "val" : "FMA:70339" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000842", "lbl" : "mononuclear cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A leukocyte with a single non-segmented nucleus in the mature form.", "xrefs" : [ "GOC:add" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mononuclear leukocyte" }, { "pred" : "hasNarrowSynonym", "val" : "peripheral blood mononuclear cell" } ], "xrefs" : [ { "val" : "BTO:0000878" }, { "val" : "CALOHA:TS-0768" }, { "val" : "FMA:86713" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000850", "lbl" : "serotonergic neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuron that releases serotonin as a neurotransmitter.", "xrefs" : [ "SANBI:mhl" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "5-HT neuron" }, { "pred" : "hasExactSynonym", "val" : "5-hydroxytryptamine neuron" }, { "pred" : "hasRelatedSynonym", "val" : "serotinergic neuron" } ], "xrefs" : [ { "val" : "MESH:D059326" }, { "val" : "WBbt:0006837" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000988", "lbl" : "hematopoietic cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell of a hematopoietic lineage.", "xrefs" : [ "GOC:add", "GO_REF:0000031" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "haematopoietic cell" }, { "pred" : "hasExactSynonym", "val" : "haemopoietic cell" }, { "pred" : "hasExactSynonym", "val" : "hemopoietic cell" } ], "xrefs" : [ { "val" : "BTO:0000574" }, { "val" : "CALOHA:TS-2017" }, { "val" : "FMA:70366" }, { "val" : "FMA:83598" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0001035", "lbl" : "bone cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A connective tissue cell found in bone.", "xrefs" : [ "GOC:add", "GO_REF:0000034" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-9990-8331" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-11-16T04:28:16Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0001060", "lbl" : "hematopoietic oligopotent progenitor cell, lineage-negative", "type" : "CLASS", "meta" : { "definition" : { "val" : "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers.", "xrefs" : [ "GOC:tfm", "PMID:19022770" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-01-06T03:43:27Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0001061", "lbl" : "abnormal cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell found in an organism or derived from an organism exhibiting a phenotype that deviates from the expected phenotype of any native cell type of that organism. Abnormal cells are typically found in disease states or disease models.", "xrefs" : [ "GOC:add", "GOC:cg", "GOC:wdd" ] }, "comments" : [ "https://github.com/obophenotype/cell-ontology/issues/448" ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C12913" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-9990-8331" }, { "pred" : "http://purl.org/dc/terms/date", "val" : "2017-01-30T18:53:32Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0001063", "lbl" : "neoplastic cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An abnormal cell exhibiting dysregulation of cell proliferation or programmed cell death and capable of forming a neoplasm, an aggregate of cells in the form of a tumor mass or an excess number of abnormal cells (liquid tumor) within an organism.", "xrefs" : [ "GOC:add", "GOC:cg", "GOC:wdd" ] }, "comments" : [ "https://github.com/obophenotype/cell-ontology/issues/448" ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "tumor cell" }, { "pred" : "hasRelatedSynonym", "val" : "tumour cell" } ], "xrefs" : [ { "val" : "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C12922" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-9990-8331" }, { "pred" : "http://purl.org/dc/terms/date", "val" : "2017-01-30T19:16:26Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0001064", "lbl" : "malignant cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neoplastic cell that is capable of entering a surrounding tissue", "xrefs" : [ "GOC:add", "GOC:cg", "GOC:wdd" ] }, "comments" : [ "https://github.com/obophenotype/cell-ontology/issues/448" ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "cancer cell" } ], "xrefs" : [ { "val" : "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C12917" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-9990-8331" }, { "pred" : "http://purl.org/dc/terms/date", "val" : "2017-01-30T19:39:12Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0001066", "lbl" : "erythroid progenitor cell, mammalian", "type" : "CLASS", "meta" : { "definition" : { "val" : "A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative).", "xrefs" : [ "GOC:add", "ISBN:0721601464" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "blast forming unit erythroid" }, { "pred" : "hasRelatedSynonym", "val" : "burst forming unit erythroid" }, { "pred" : "hasRelatedSynonym", "val" : "colony forming unit erythroid" }, { "pred" : "hasRelatedSynonym", "val" : "erythroid stem cell" } ], "xrefs" : [ { "val" : "BTO:0004911" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002031", "lbl" : "hematopoietic lineage restricted progenitor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells.", "xrefs" : [ "GOC:tfm", "PMID:19022770" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-01-06T03:43:20Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002032", "lbl" : "hematopoietic oligopotent progenitor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities.", "xrefs" : [ "GOC:tfm", "PMID:19022770", "https://orcid.org/0000-0001-5208-3432" ] }, "comments" : [ "This cell type is intended to be compatible with any vertebrate hematopoietic oligopotent progenitor cell. For mammalian hematopoietic oligopotent progenitor cells known to be lineage-negative, please use the term 'hematopoietic oligopotent progenitor cell' (CL_0001060)." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-01-06T03:43:27Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002067", "lbl" : "type A enteroendocrine cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An enteroendocrine cell that produces glucagon.", "xrefs" : [ "GOC:tfm", "ISBN:0412046911" ] }, "xrefs" : [ { "val" : "FMA:62939" }, { "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002067" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-10T10:48:54Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002068", "lbl" : "Purkinje myocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter.", "xrefs" : [ "FMA:0412046911", "GOC:tfm", "PMID:19939742" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Purkinje cell fiber" }, { "pred" : "hasExactSynonym", "val" : "Purkinje muscle cell" }, { "pred" : "hasExactSynonym", "val" : "myocytus conducens cardiacus" } ], "xrefs" : [ { "val" : "BTO:0001032" }, { "val" : "FMA:14146" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-06-28T08:36:15Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002072", "lbl" : "nodal myocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery.", "xrefs" : [ "FMA:67101", "GOC:tfm" ] }, "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "pacemaker cell" }, { "pred" : "hasExactSynonym", "val" : "P cell" }, { "pred" : "hasExactSynonym", "val" : "cardiac pacemaker cell", "xrefs" : [ "GOC:pr" ] }, { "pred" : "hasExactSynonym", "val" : "myocytus nodalis" } ], "xrefs" : [ { "val" : "BTO:0004190" }, { "val" : "FMA:67101" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-06-29T11:41:37Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002073", "lbl" : "transitional myocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "Specialized cardiac myocyte which is in the internodal tract and atrioventricular node. The cell is more slender than ordinary atrial myocytes and has more myofibrils than nodal myocytes.", "xrefs" : [ "FMA:67142", "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:67142" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-06-29T02:39:32Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002074", "lbl" : "myocardial endocrine cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "The myoendocrine cellis a specialized myocyte localized mainly in the right and left atrial appendages, and also scattered within other areas of the atria and along the conductive system in the ventricular septum. The most conspicuous feature distinguishing myoendocrine cells from other atrial myoctyes is the presence of membane-bounded secretory granules (these granules contain precursor of cardiodilatins or atrial natriuretic polypeptides).", "xrefs" : [ "FMA:67111", "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:67111" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-06-29T11:50:47Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002076", "lbl" : "endo-epithelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An epithelial cell derived from endoderm.", "xrefs" : [ "FMA:69075", "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:69075" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-06-29T03:38:14Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002077", "lbl" : "ecto-epithelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An epithelial cell derived from ectoderm.", "xrefs" : [ "FMA:69074", "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:69074" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-06-29T03:38:22Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002078", "lbl" : "meso-epithelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Epithelial cell derived from mesoderm or mesenchyme.", "xrefs" : [ "FMA:69076", "GOC:tfm" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epithelial mesenchymal cell" } ], "xrefs" : [ { "val" : "FMA:69076" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-06-29T03:49:14Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002086", "lbl" : "specialized cardiac myocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart.", "xrefs" : [ "FMA:67968", "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:67968" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-07-21T01:33:38Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002087", "lbl" : "nongranular leukocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "A leukocyte that lacks granules.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "agranular leukocyte" } ], "xrefs" : [ { "val" : "FMA:62855" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-07-22T11:30:33Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002092", "lbl" : "bone marrow cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, "comments" : [ "MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0004850" }, { "val" : "FMA:83621" }, { "val" : "MESH:D001854" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-07-22T04:48:15Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002095", "lbl" : "hilus cell of ovary", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell in the hilum of the ovary that produces androgens.", "xrefs" : [ "GOC:tfm", "ISBN:068340007X" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "hilar cell of ovary" } ], "xrefs" : [ { "val" : "FMA:18710" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-08-23T11:18:18Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002132", "lbl" : "stromal cell of ovary", "type" : "CLASS", "meta" : { "definition" : { "val" : "A stomal cell of the ovary", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "ovarian stromal cell", "xrefs" : [ "GOC:cjm" ] } ], "xrefs" : [ { "val" : "FMA:72299" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-08-23T12:10:31Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002139", "lbl" : "endothelial cell of vascular tree", "type" : "CLASS", "meta" : { "definition" : { "val" : "An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels.", "xrefs" : [ "GOC:dsd", "GOC:tfm", "PMID:12768659" ] }, "comments" : [ "These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "vascular endothelial cell" }, { "pred" : "hasNarrowSynonym", "val" : "cubodial endothelial cell of vascular tree" } ], "xrefs" : [ { "val" : "BTO:0001854" }, { "val" : "CALOHA:TS-1106" }, { "val" : "FMA:67755" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-08-24T02:06:40Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002144", "lbl" : "capillary endothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An endothelial cell found in capillaries.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0004956" }, { "val" : "CALOHA:TS-0112" }, { "val" : "FMA:67756" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-08-24T10:15:00Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002159", "lbl" : "general ecto-epithelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Epithelial cells derived from general body ectoderm and ectoderm placodes.", "xrefs" : [ "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:70556" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-08-26T08:31:08Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002178", "lbl" : "epithelial cell of stomach", "type" : "CLASS", "meta" : { "definition" : { "val" : "An epithelial cell found in the lining of the stomach.", "xrefs" : [ "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:62948" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-08-25T03:22:08Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002183", "lbl" : "stem cell of gastric gland", "type" : "CLASS", "meta" : { "definition" : { "val" : "A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit.", "xrefs" : [ "GOC:tfm", "ISBN:0517223651" ] }, "xrefs" : [ { "val" : "FMA:62953" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-08-25T03:57:08Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002222", "lbl" : "vertebrate lens cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim" ], "xrefs" : [ { "val" : "FMA:70950" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-07T10:38:03Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002224", "lbl" : "lens epithelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544", "http://en.wikipedia.org/wiki/Lens_%28anatomy%29#Lens_epithelium" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "FMA:67559" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-07T10:45:47Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002240", "lbl" : "marrow fibroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "A fibroblast in the bone marrow.", "xrefs" : [ "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:84377" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-07T02:25:18Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002242", "lbl" : "nucleate cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell containing at least one nucleus.", "xrefs" : [ "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:67513" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-07T03:32:33Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002246", "lbl" : "peripheral blood stem cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells).", "xrefs" : [ "GOC:tfm" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "PBSC" } ], "xrefs" : [ { "val" : "BTO:0002669" }, { "val" : "FMA:86711" }, { "val" : "MESH:D000072916" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-07T03:57:09Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002251", "lbl" : "epithelial cell of alimentary canal", "type" : "CLASS", "meta" : { "definition" : { "val" : "An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-08T09:26:53Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002252", "lbl" : "epithelial cell of esophagus", "type" : "CLASS", "meta" : { "definition" : { "val" : "An epithelial cell of the esophagus.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "FMA:63071" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-08T09:28:20Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002262", "lbl" : "endothelial cell of sinusoid", "type" : "CLASS", "meta" : { "definition" : { "val" : "An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "FMA:63134" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-14T10:57:26Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002264", "lbl" : "type A cell of stomach", "type" : "CLASS", "meta" : { "definition" : { "val" : "A type of enteroendocrine cell found in the stomach that secretes glucagon.", "xrefs" : [ "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:83411" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-10T10:54:42Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002308", "lbl" : "epithelial cell of skin gland", "type" : "CLASS", "meta" : { "definition" : { "val" : "An epithelial cell of a skin gland.", "xrefs" : [ "GOC:tfm" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epithelial cell of gland of skin" } ], "xrefs" : [ { "val" : "FMA:70657" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-14T12:00:07Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002319", "lbl" : "neural cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell that is part of the nervous system.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-2040" }, { "val" : "FMA:70333" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-15T01:34:57Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002320", "lbl" : "connective tissue cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-2096" }, { "val" : "FMA:63875" }, { "val" : "MESH:D003239" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-15T03:01:54Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002321", "lbl" : "embryonic cell (metazoa)", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell of the embryo.", "xrefs" : [ "FMA:0618947256" ] }, "xrefs" : [ { "val" : "CALOHA:TS-0263" }, { "val" : "FMA:82840" }, { "val" : "WBbt:0007028" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-15T03:39:21Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002333", "lbl" : "neural crest derived adipocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "An adipocyte derived from a neural crest cell.", "xrefs" : [ "GOC:tfm", "PMID:17507398" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-20T02:25:25Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002350", "lbl" : "endocardial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin.", "xrefs" : [ "GOC:tfm", "ISSN:0452-3458" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "endocardial endothelial cell" }, { "pred" : "hasExactSynonym", "val" : "endothelial cell of endocardium", "xrefs" : [ "FMA:75621" ] } ], "xrefs" : [ { "val" : "FMA:75621" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-21T04:33:05Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002352", "lbl" : "gestational hematopoietic stem cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A hematopoietic stem cell that exists during embryogenesis.", "xrefs" : [ "GOC:tfm", "ISBN:978-60327-246-6" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-22T09:05:13Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002363", "lbl" : "keratocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate.", "xrefs" : [ "GOC:tfm", "ISBN:9780702029585" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "corneal fibroblast" }, { "pred" : "hasExactSynonym", "val" : "corneal keratocyte" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-22T01:57:40Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002368", "lbl" : "respiratory epithelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An endo-epithelial cell of the respiratory tract.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "airway epithelial cell" } ], "xrefs" : [ { "val" : "BTO:0004533" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-23T04:38:49Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002372", "lbl" : "myotube", "type" : "CLASS", "meta" : { "definition" : { "val" : "A transversely striated, multinucleated syncytial muscle cell, formed by the fusion of myoblasts during muscle development.", "xrefs" : [ "GOC:dos", "GOC:tfm", "ISBN:0323052908", "PMID:22274696" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "myofiber", "xrefs" : [ "FBbt:00005812" ] }, { "pred" : "hasExactSynonym", "val" : "myofibril", "xrefs" : [ "FBbt:00005812" ] } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-24T01:13:01Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002375", "lbl" : "Schwann cell precursor", "type" : "CLASS", "meta" : { "definition" : { "val" : "A multipotent progenitor cell that develops from a migratory neural crest cell. The schwann cell precursor is embedded among axons, with minimal extracellular space separating them from nerve cell membranes. This cell lacks a basal lamina, which distinguishes it from more mature Schwann cells. In rodents, cadherin-19 (Cdh19) serves as a specific marker for this developmental stage.", "xrefs" : [ "GOC:tfm", "PMID:15580626", "PMID:30971890", "PMID:35815410" ] }, "comments" : [ "Schwann cell precursor are capable of differentiating into Schwann cells and other cell types such as melanocytes, neurons, and mesenchymal cells." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Schwann cell precursor cell" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-24T02:06:10Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002377", "lbl" : "immature Schwann cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A glial cell that develops from a Schwann cell precursor. The immature Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. Immature Schwann cell can be found communally ensheathing large groups of axons.", "xrefs" : [ "GOC:cvs", "GOC:tfm", "ISBN:0721662544" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "Schwann cell" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-09-24T02:10:31Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002421", "lbl" : "nucleated reticulocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles.", "xrefs" : [ "GOC:tfm", "PMID:18182572", "PMID:9011180", "PMID:9046052" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-10-15T09:24:05Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002422", "lbl" : "enucleated reticulocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "A reticulocyte lacking a nucleus and showing a basophilic reticulum under vital staining due to the presence of ribosomes.", "xrefs" : [ "GOC:tfm", "ISBN:0-12203-052-4", "ISBN:0721601464" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-0864" }, { "val" : "FMA:66785" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-10-15T09:24:08Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002453", "lbl" : "oligodendrocyte precursor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A progenitor cell of the central nervous system that can differentiate into oligodendrocytes or type-2 astrocytes. This cell originates from multiple structures within the developing brain including the medial ganglion eminence and the lateral ganglionic eminence. These cells migrate throughout the central nervous system and persist into adulthood where they play an important role in remyelination of injured neurons.", "xrefs" : [ "GOC:tfm", "PMID:10704434", "PMID:11756508", "PMID:20142420", "PMID:2182078", "PMID:24133281", "PMID:9826671" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "oligodendrocyte-type 2 astrocyte (O-2A) progenitor cell", "xrefs" : [ "PMID:2253328" ] }, { "pred" : "hasBroadSynonym", "val" : "oligodendrocyte/type-2 astrocyte progenitor cell", "xrefs" : [ "PMID:24133281" ] } ], "xrefs" : [ { "val" : "MESH:D000073637" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-11-10T02:51:34Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002494", "lbl" : "cardiocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell located in the heart, including both muscle and non muscle cells.", "xrefs" : [ "GOC:tfm" ] }, "comments" : [ "From Onard of the FMA: Cardiac muscle cell or cardiac myocyte is a striated muscle cell. Cardiocyte on the other hand is any cell in the heart which includes cells other than muscle cells (e.g. endothelial cell of endocardium). Unless there is a consensus among anatomists that cardiocytes refer only to muscle cells, we will treat them as a general class of cells in the heart." ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "heart cell" } ], "xrefs" : [ { "val" : "BTO:0001539" }, { "val" : "CALOHA:TS-0115" }, { "val" : "FMA:83808" }, { "val" : "FMA:84791" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-12-07T09:37:22Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002503", "lbl" : "adventitial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0002441" }, { "val" : "FMA:84639" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-12-07T04:03:56Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002521", "lbl" : "subcutaneous adipocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "An adipocyte that is part of subcutaneous adipose tissue.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "subcutaneous fat cell" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-02-21T02:51:22Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002539", "lbl" : "aortic smooth muscle cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A smooth muscle cell of the aorta.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0004577" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-02-28T01:42:12Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002540", "lbl" : "mesenchymal stem cell of the bone marrow", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mesenchymal stem cell that is part of the bone marrow.", "xrefs" : [ "GOC:tfm" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-02-28T01:47:47Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002543", "lbl" : "vein endothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An endothelial cell that is part of the vein.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "endothelial cell of vein" }, { "pred" : "hasExactSynonym", "val" : "venous endothelial cell" } ], "xrefs" : [ { "val" : "FMA:62104" }, { "val" : "KUPO:0001099" }, { "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002543" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-02-28T03:48:11Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002547", "lbl" : "fibroblast of the aortic adventitia", "type" : "CLASS", "meta" : { "definition" : { "val" : "A fibroblast of the aortic adventitia.", "xrefs" : [ "GOC:tfm" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-02-28T04:43:41Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002548", "lbl" : "fibroblast of cardiac tissue", "type" : "CLASS", "meta" : { "definition" : { "val" : "A fibroblast that is part of the heart.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cardiac fibroblast" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-02-28T04:57:44Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002551", "lbl" : "fibroblast of dermis", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any skin fibroblast that is part of some dermis.", "xrefs" : [ "FBC:Autogenerated" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-02-28T05:05:33Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002553", "lbl" : "fibroblast of lung", "type" : "CLASS", "meta" : { "definition" : { "val" : "A fibroblast that is part of lung.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0000764" }, { "val" : "CALOHA:TS-0575" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-02-28T05:11:03Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002557", "lbl" : "fibroblast of pulmonary artery", "type" : "CLASS", "meta" : { "definition" : { "val" : "A fibroblast of pulmonary artery.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-02-28T05:22:27Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002570", "lbl" : "mesenchymal stem cell of adipose tissue", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mesenchymal stem cell of adipose tissue.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesenchymal stem cell of adipose" } ], "xrefs" : [ { "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002570" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-03-01T09:57:17Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002573", "lbl" : "Schwann cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A glial cell that myelinates or ensheathes axons in the peripheral nervous system.", "xrefs" : [ "GOC:tfm", "PMID:16807057" ] }, "comments" : [ "A myelinating Schwann cell wraps around a single axon. Myelination occurs in larger diameter axons, while a process called ensheathment occurs on smaller diameter axons in which a single cell wraps around multiple small, unmyelinated axons separating them with a thin layer of cytoplasm. The structure formed is called a Remak bundle." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neurolemmocyte", "xrefs" : [ "PMID:32119275", "PMID:38638689" ] } ], "xrefs" : [ { "val" : "BTO:0001220" }, { "val" : "CALOHA:TS-0898" }, { "val" : "MESH:D012583" }, { "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002573" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-03-02T01:19:27Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002585", "lbl" : "retinal blood vessel endothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A blood vessel endothelial cell that is part of the retina.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "https://cellxgene.cziscience.com/cellguide/CL_0002585" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-03-06T03:28:27Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002589", "lbl" : "smooth muscle cell of the brachiocephalic vasculature", "type" : "CLASS", "meta" : { "definition" : { "val" : "A smooth muscle cell of the bachiocephalic vasculature.", "xrefs" : [ "GOC:tfm" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-03-06T05:00:58Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002590", "lbl" : "smooth muscle cell of the brain vasculature", "type" : "CLASS", "meta" : { "definition" : { "val" : "A vascular associated smooth muscle cell of the brain vasculature.", "xrefs" : [ "GOC:tfm" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-03-06T05:01:20Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002591", "lbl" : "smooth muscle cell of the pulmonary artery", "type" : "CLASS", "meta" : { "definition" : { "val" : "A smooth muscle of the pulmonary artery.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0003336" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-03-06T05:01:28Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002595", "lbl" : "smooth muscle cell of the subclavian artery", "type" : "CLASS", "meta" : { "definition" : { "val" : "A smooth muscle cell of the subclavian artery.", "xrefs" : [ "GOC:tfm" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-03-06T05:01:52Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002596", "lbl" : "smooth muscle cell of the carotid artery", "type" : "CLASS", "meta" : { "definition" : { "val" : "Smooth muscle cell of the carotid artery.", "xrefs" : [ "GOC:tfm" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-03-06T05:01:56Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002599", "lbl" : "smooth muscle cell of the esophagus", "type" : "CLASS", "meta" : { "definition" : { "val" : "A smooth muscle cell of the esophagus.", "xrefs" : [ "GOC:tfm" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-03-06T05:48:17Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002610", "lbl" : "raphe nuclei neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuron of the raphe nuclei.", "xrefs" : [ "GOC:tfm" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-03-06T07:42:06Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002612", "lbl" : "neuron of the ventral spinal cord", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuron of the ventral spinal cord.", "xrefs" : [ "GOC:tfm" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-03-06T07:46:03Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002620", "lbl" : "skin fibroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "A fibroblast of skin.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0001255" }, { "val" : "CALOHA:TS-0935" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-03-14T12:31:49Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002632", "lbl" : "epithelial cell of lower respiratory tract", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any epithelial cell that is part of some lower respiratory tract epithelium.", "xrefs" : [ "FBC:Autogenerated" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-06-21T12:29:31Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002653", "lbl" : "squamous endothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A squamous shaped endothelial cell.", "xrefs" : [ "GOC:dos" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-07-08T03:31:25Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002657", "lbl" : "glandular cell of esophagus", "type" : "CLASS", "meta" : { "definition" : { "val" : "A glandular epithelial cell of the esophagus.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "FMA:86548" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-07-08T03:55:57Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002659", "lbl" : "glandular epithelial cell of stomach", "type" : "CLASS", "meta" : { "definition" : { "val" : "A glandular epithelial cell that is part of the stomach.", "xrefs" : [ "GOC:tfm" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "glandular cell of stomach" } ], "xrefs" : [ { "val" : "CALOHA:TS-1284" }, { "val" : "FMA:86554" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-07-11T01:20:35Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002663", "lbl" : "myocardial endocrine cell of atrium", "type" : "CLASS", "meta" : { "definition" : { "val" : "A myocardial endocrine cell that is part of the atrium.", "xrefs" : [ "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:83389" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-07-11T02:45:39Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002664", "lbl" : "cardioblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart.", "xrefs" : [ "GOC:tfm", "PMID:19745164" ] }, "comments" : [ "Discrepancy in develops from origins prevents me from making the assertion that cardioblasts give rise to all instances of cardiocytes as we state cardiac muscle cells develop from cardiac myoblast, which in turn develop from muscle stem cell." ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cardiovascular progenitor cell", "xrefs" : [ "PMID:17519333", "PMID:19745164" ] } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-07-11T03:15:38Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002672", "lbl" : "retinal progenitor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells.", "xrefs" : [ "GOC:tfm", "PMID:20959166", "PMID:21148186" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-08-16T02:38:01Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002673", "lbl" : "tongue muscle cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A skeletal muscle cell that is part of the tongue.", "xrefs" : [ "GOC:tfm", "PMID:18816858" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-08-16T03:10:02Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0002676", "lbl" : "neural crest derived neuroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuroblast derived from a neural crest cell.", "xrefs" : [ "GOC:tfm", "PMID:17407019" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-08-22T09:24:15Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0003001", "lbl" : "bistratified retinal ganglion cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A retinal ganglion cell that has dendrites stratified in two layers of the inner-plexiform layer." }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "retinal ganglion D cell" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-7258-9596" }, { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0002-5260-9315" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0004246", "lbl" : "monostratified cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A central nervous system neuron that stratifies at one and only one location.", "xrefs" : [ "PMID:9620701" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-7258-9596" }, { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0002-5260-9315" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0004247", "lbl" : "bistratified cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuron that stratifies dendrites at two and only two locations.", "xrefs" : [ "PMID:9620701", "https://orcid.org/0000-0002-5260-9315" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-7258-9596" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0005000", "lbl" : "spinal cord interneuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A CNS interneuron located in the spinal cord.", "xrefs" : [ "CL:CVS" ] }, "comments" : [ "Is_a interneuron, part_of UBERON:0002240." ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0005012", "lbl" : "multi-ciliated epithelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A columnar/cuboidal epithelial cell with multiple motile cilia on its apical surface. These cells facilitate the movement of liquids such as mucus or cerebrospinal fluid across the epithelial surface.", "xrefs" : [ "CL:CVS", "PMID:28400610", "PMID:30422572", "PMID:38032388" ] }, "comments" : [ "While the term 'multi-ciliated epithelial cell' refers to cells with multiple motile cilia, there are exceptions where epithelial cells may have multiple non-motile cilia. Examples include olfactory sensory neurons, which have non-motile cilia for sensory detection, and choroid plexus epithelial cells, which possess multiple non-motile cilia with transient motility during development. Multiciliated cells are essential for human health, and their dysfunction can lead to various diseases known as ciliopathies, such as primary ciliary dyskinesia. This condition affects the respiratory system, brain ventricles, and reproductive system, leading to chronic respiratory infections, hydrocephalus, and infertility" ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "multi-ciliated cell" }, { "pred" : "hasBroadSynonym", "val" : "multiciliated cell" }, { "pred" : "hasExactSynonym", "val" : "multiciliated epithelial cell" } ], "xrefs" : [ { "val" : "https://cellxgene.cziscience.com/cellguide/CL_0005012" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0005024", "lbl" : "somatomotor neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A motor neuron that innervates a skeletal muscle. These motor neurons are all excitatory and cholinergic.", "xrefs" : [ "ZFIN:CVS" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "somatic motor neuron" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0007001", "lbl" : "skeletogenic cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Cell that has the potential to form a skeletal cell type (e.g. cells in periosteum, cells in marrow) and produce extracellular matrix (often mineralized) and skeletal tissue (often mineralized).", "xrefs" : [ "GO_REF:0000034" ] }, "comments" : [ "Needs logical definition. Should be capable_of skeletal system morphogenesis? or skeletal tissue development? needs to be added to GO. NOTES:a cell type of the early embryo (see also: mesenchymal cells) that will give rise to mineralized connective tissue. Scleroblasts can differentiate into osteoblasts (bone-forming cells), chondroblasts (cartilage-forming cells), odontoblasts (dentin-forming cells), ameloblasts (enamel-forming cells). The mesenchymal cells developing into osteoblasts and chondroblasts are derived from the mesoderm. Those developing into odontoblasts are neural crest cells. Those developing into ameloblasts are derived from the ectoderm. (http://www.copewithcytokines.de/cope.cgi?key=scleroblasts)" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "scleroblast", "xrefs" : [ "GO_REF:0000034" ] } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-9114-8737" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2012-06-15T02:51:27Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0007004", "lbl" : "premigratory neural crest cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells.", "xrefs" : [ "UBERONREF:0000002" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-9114-8737" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2012-06-27T08:27:35Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0007009", "lbl" : "prechondroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "Skeletogenic cell that has the potential to develop into a chondroblast; and arises from neural crest, meseosdermal and notochordal and connective tissue cells.", "xrefs" : [ "GO_REF:0000034" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-9114-8737" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2012-06-27T10:44:01Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008000", "lbl" : "non-striated muscle cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any muscle cell in which the fibers are not organised into sarcomeres.", "xrefs" : [ "GOC:DOS" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008001", "lbl" : "hematopoietic precursor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any hematopoietic cell that is a precursor of some other hematopoietic cell type.", "xrefs" : [ "GOC:dos" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008002", "lbl" : "skeletal muscle fiber", "type" : "CLASS", "meta" : { "definition" : { "val" : "A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.", "xrefs" : [ "GOC:tfm", "ISBN:0323052908" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "MESH:D018485" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008007", "lbl" : "visceral muscle cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A muscle cell that is part of some visceral muscle.", "xrefs" : [ "GOC:dos" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008008", "lbl" : "striated visceral muscle cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A visceral muscle cell that is striated. Examples include the visceral muscle cells of arhtropods.", "xrefs" : [ "GOC:dos" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008009", "lbl" : "transversely striated visceral muscle cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A visceral muscle that is transversely striated. Examples include the visceral muscle cells of arthropods.", "xrefs" : [ "GOC:dos" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008017", "lbl" : "adult skeletal muscle myoblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "A skeletal muscle myoblast that is part of a skeletal mucle. These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers.", "xrefs" : [ "PMID:23303905" ] }, "comments" : [ "The vast majority of these cells develop from skeletal muscle satellite cells, although there are some reports of other origins." ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "myogenic precursor cell", "xrefs" : [ "PMID:23303905" ] } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008019", "lbl" : "mesenchymal cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesenchyme cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008022", "lbl" : "endocardial cushion cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mesenchymal cell of the endocardial cushion. These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves.", "xrefs" : [ "PMID:18816864" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008025", "lbl" : "noradrenergic neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter.", "xrefs" : [ "GOC:dos" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008028", "lbl" : "visual system neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any neuron that is capable of part of some visual perception.", "xrefs" : [ "FBC:Autogenerated" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0002-7073-9172" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2017-07-09T19:12:36Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008031", "lbl" : "cortical interneuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "An interneuron that has its soma located in the cerebral cortex." }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cerebral cortex interneuron" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008034", "lbl" : "mural cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation.", "xrefs" : [ "Wiki:Mural_cell&oldid=930603194" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#added_for_HCA", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0002-7073-9172" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2020-02-29T17:33:55Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008035", "lbl" : "microcirculation associated smooth muscle cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any vascular associated smooth muscle cell that is part of some microcirculatory vessel.", "xrefs" : [ "FBC:Autogenerated" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0002-7073-9172" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2020-02-29T17:37:00Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0009000", "lbl" : "sensory neuron of spinal nerve", "type" : "CLASS", "meta" : { "definition" : { "val" : "A sensory neuron of the spinal nerve that senses body position and sends information about how much the muscle is stretched to the spinal cord.", "xrefs" : [ "GOC:nv", "GOC:pr" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "spinal sensory neuron" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0009001", "lbl" : "compound eye retinal cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any cell in the compound eye, a light sensing organ composed of ommatidia." }, "xrefs" : [ { "val" : "GOC:pr" }, { "val" : "PMID:12021768" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0009004", "lbl" : "retinal cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any cell in the retina, the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.", "xrefs" : [ "GOC:pr" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], "xrefs" : [ { "val" : "PMID:10702418" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0009097", "lbl" : "embryonic skeletal muscle fiber", "type" : "CLASS", "meta" : { "definition" : { "val" : "A skeletal muscle fiber found in an embryo. In mammalian embryos, skeletal muscle expresses myosin heavy chain-embryonic (MyHC-emb, encoded by the MYH3 gene), which regulates skeletal muscle development.", "xrefs" : [ "PMID:32094117", "PMID:7196501", "http://orcid.org/0000-0003-2034-601X" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0002-2825-0621" }, { "pred" : "http://purl.org/dc/terms/date", "val" : "2022-02-21T15:39:10Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0010001", "lbl" : "stromal cell of bone marrow", "type" : "CLASS", "meta" : { "definition" : { "val" : "A stromal cell that is part_of a bone marrow." }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "bone marrow stromal cell" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0002-6601-2165" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0010004", "lbl" : "mononuclear cell of bone marrow", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mononuclear cell that is part_of a bone marrow." }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "bone marrow mononuclear cell" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0002-6601-2165" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0010006", "lbl" : "cardiac blood vessel endothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any blood vessel endothelial cell that is part of some heart.", "xrefs" : [ "FBC:Autogenerated" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0010007", "lbl" : "His-Purkinje system cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any cell that is part of some His-Purkinje system.", "xrefs" : [ "FBC:Autogenerated" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0010008", "lbl" : "cardiac endothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any endothelial cell that is part of some heart.", "xrefs" : [ "FBC:Autogenerated" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0010009", "lbl" : "camera-type eye photoreceptor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any photoreceptor cell that is part of some camera-type eye.", "xrefs" : [ "FBC:Autogenerated" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "camera type eye photoreceptor cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0010012", "lbl" : "cerebral cortex neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A CNS neuron of the cerebral cortex.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cortical neuron" }, { "pred" : "hasExactSynonym", "val" : "neuron of cerebral cortex" } ], "xrefs" : [ { "val" : "BTO:0004102" }, { "val" : "FMA:84104" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-7258-9596" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0010017", "lbl" : "zygote", "type" : "CLASS", "meta" : { "definition" : { "val" : "A zygote in a plant or an animal." }, "xrefs" : [ { "val" : "MESH:D015053" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0010020", "lbl" : "cardiac glial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any glial cell that is part of some heart.", "xrefs" : [ "FBC:Autogenerated" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0010021", "lbl" : "cardiac myoblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any myoblast that develops into some cardiac muscle cell.", "xrefs" : [ "FBC:Autogenerated" ] }, "xrefs" : [ { "val" : "MESH:D032386" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0010022", "lbl" : "cardiac neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuron that has its soma in the heart.", "xrefs" : [ "PMID:12486170", "PMID:29265764" ] }, "comments" : [ "This term is used in 3 GO terms that were created as part of the heart development focus project." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0011001", "lbl" : "spinal cord motor neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement.", "xrefs" : [ "GOC:nv" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0011007", "lbl" : "paraxial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites.", "xrefs" : [ "GOC:NV", "PMID:11687492" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "paraxial mesoderm cell" }, { "pred" : "hasExactSynonym", "val" : "somitic mesoderm cell" }, { "pred" : "hasNarrowSynonym", "val" : "presomitic mesoderm cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0011012", "lbl" : "neural crest cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells.", "xrefs" : [ "https://orcid.org/0000-0001-5208-3432", "https://orcid.org/0000-0002-9900-7880" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "https://cellxgene.cziscience.com/cellguide/CL_0011012" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0011019", "lbl" : "mesothelial cell of epicardium", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mesothelial cell that is part of the epicardium." }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-5208-3432" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0011021", "lbl" : "fibroblast of upper back skin", "type" : "CLASS", "meta" : { "definition" : { "val" : "A fibroblast that is part of upper back skin." }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-5208-3432" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0011022", "lbl" : "fibroblast of skin of back", "type" : "CLASS", "meta" : { "definition" : { "val" : "A fibroblast that is part of skin of back." }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-5208-3432" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0011026", "lbl" : "progenitor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses.", "xrefs" : [ "ISBN:978-1-62808-994-3", "https://doi.org/10.1016/B978-0-12-409503-8.00002-0" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-5208-3432" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0011027", "lbl" : "skeletal muscle fibroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any fibroblast that is part of skeletal muscle tissue.", "xrefs" : [ "PMID:28369879", "https://orcid.org/0000-0001-6164-0667" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "skeleton muscle fibroblast" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-5208-3432" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0011030", "lbl" : "dermal microvascular endothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any microvascular endothelial cell that is part of the dermis.", "xrefs" : [ "BTO:0004574", "CL:patterns/cellPartOfAnatomicalEntity" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "DMEC cell" }, { "pred" : "hasExactSynonym", "val" : "dermal microvascular endothelium cell" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-5208-3432" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0011115", "lbl" : "precursor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell that, by division or terminal differentiation, can give rise to other cell types.", "xrefs" : [ "GOC:dos" ] }, "comments" : [ "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell." ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0012001", "lbl" : "neuron of the forebrain", "type" : "CLASS", "meta" : { "definition" : { "val" : "A CNS neuron of the forebrain." }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "forebrain neuron" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0002-3837-8864" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0017500", "lbl" : "neutrophillic cytoplasm", "type" : "CLASS", "meta" : { "definition" : { "val" : "Cytoplasm that exhibits a characteristic staining and color, pale-pink, with Wright-Giemsa stain.", "xrefs" : [ "GOC:add" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-05-25T01:36:34Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0017502", "lbl" : "acidophilic cytoplasm", "type" : "CLASS", "meta" : { "definition" : { "val" : "Cytoplasm that exhibits a characteristic staining and color, red or pink, with Eosin stain.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "eosinophilic" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-22T04:23:25Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0017503", "lbl" : "basophilic cytoplasm", "type" : "CLASS", "meta" : { "definition" : { "val" : "Cytoplasm that exhibits molecular interaction for basic dyes under specific pH conditions.", "xrefs" : [ "GOC:tfm" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-22T04:24:54Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0017504", "lbl" : "polychromatophilic cytoplasm", "type" : "CLASS", "meta" : { "definition" : { "val" : "Cytoplasm that exhibits affinity for both basic and acid stains under specific pH conditions.", "xrefs" : [ "GOC:tfm" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-28T04:25:23Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0017507", "lbl" : "reniform nucleus", "type" : "CLASS", "meta" : { "definition" : { "val" : "A concave nucleus shape where the indentation is smaller than half of the distance to the farthest nuclear margin.", "xrefs" : [ "GOC:tfm" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-1980-3228" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-23T02:31:25Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0017509", "lbl" : "alobate nucleus", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any nucleus that has characteristic some alobate.", "xrefs" : [ "FBC:Autogenerated" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_0019018", "lbl" : "blood vessel smooth muscle cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A smooth muscle cell that is part of any blood vessel.", "xrefs" : [ "PMID:9108778" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "smooth muscle cell of blood vessel" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0003-2034-601X" }, { "pred" : "http://purl.org/dc/terms/date", "val" : "2020-07-21T12:42:48Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000042", "lbl" : "forebrain neuroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any neuroblast (sensu Vertebrata) that is part of some forebrain.", "xrefs" : [ "FBC:Autogenerated" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000222", "lbl" : "stomach neuroendocrine cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any neuroendocrine cell that is part of some stomach.", "xrefs" : [ "FBC:Autogenerated" ] } } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000223", "lbl" : "lung neuroendocrine cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuroendocrine cell that is part of respiratory epithelium of the lung and is involved in the sensory detection of environmental stimuli, including hypoxia, nicotine and air pressure. Ultrastructurally, this cell type is characterized by the presence of cytoplasmic dense core granules, which are considered the storage sites of amine and peptide hormones. Lung neuroendocrine cells are innervated and appear as solitary cells or as clustered masses, localized at airway bifurcation sites, called neuroepithelial bodies that can release serotonin in response to hypoxia and interact with sensory nerve terminals. Lung neuroendocrine cells also function as reserve stem cells that repair the surrounding epithelium after injury.", "xrefs" : [ "PMID:33355253", "doi:10.3109/01902148209069653", "doi:10.7554/eLife.78216" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "pulmonary neuroendocrine cell", "xrefs" : [ "PMID:33355253" ] } ], "xrefs" : [ { "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000223" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000271", "lbl" : "lung ciliated cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An epithelial cell that is part of the lung epithelium. This cell is characterised by the presence of cilia on its apical surface.", "xrefs" : [ "PMID:27864314" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000272", "lbl" : "lung secretory cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any secretory cell that is part of some lung.", "xrefs" : [ "FBC:Autogenerated" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000274", "lbl" : "trophectodermal cell", "type" : "CLASS", "meta" : { "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "trophectoderm cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000298", "lbl" : "mesothelial cell of dura mater", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mesothelial cell that is part of the dura mater.", "xrefs" : [ "GOC:tfm" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "squamous mesothelial cell of dura mater", "xrefs" : [ "FMA:256516" ] } ], "xrefs" : [ { "val" : "FMA:256516" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000303", "lbl" : "fibroblast of areolar connective tissue", "type" : "CLASS", "meta" : { "definition" : { "val" : "A fibroblast that is part of the areolar connective tissue.", "xrefs" : [ "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:261279" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000306", "lbl" : "fibroblast of tunica adventitia of artery", "type" : "CLASS", "meta" : { "definition" : { "val" : "A fibroblast that is part of the tunica adventitia of artery.", "xrefs" : [ "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:261285" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000307", "lbl" : "fibroblast of dense regular elastic tissue", "type" : "CLASS", "meta" : { "definition" : { "val" : "A fibroblast that is part of the dense regular elastic tissue.", "xrefs" : [ "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:261287" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000309", "lbl" : "epicardial adipocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "An adipocyte that is part of the epicardial fat.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "adipocyte of epicardial fat", "xrefs" : [ "FMA:261293" ] }, { "pred" : "hasExactSynonym", "val" : "epicardial fat cell", "xrefs" : [ "FMA:261293" ] } ], "xrefs" : [ { "val" : "FMA:261293" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000310", "lbl" : "adipocyte of epicardial fat of right ventricle", "type" : "CLASS", "meta" : { "definition" : { "val" : "An adipocyte that is part of the epicardial fat of right ventricle.", "xrefs" : [ "GOC:tfm" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epicardial adipocyte of right ventricle", "xrefs" : [ "FMA:261297" ] }, { "pred" : "hasExactSynonym", "val" : "epicardial fat cell of right ventricle", "xrefs" : [ "FMA:261297" ] } ], "xrefs" : [ { "val" : "FMA:261297" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000311", "lbl" : "adipocyte of epicardial fat of left ventricle", "type" : "CLASS", "meta" : { "definition" : { "val" : "An adipocyte that is part of the epicardial fat of left ventricle.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epicardial adipocyte of left ventricle", "xrefs" : [ "FMA:261300" ] }, { "pred" : "hasExactSynonym", "val" : "epicardial fat cell of left ventricle", "xrefs" : [ "FMA:261300" ] } ], "xrefs" : [ { "val" : "FMA:261300" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000361", "lbl" : "transitional myocyte of interatrial septum", "type" : "CLASS", "meta" : { "definition" : { "val" : "A transitional myocyte that is part of the interatrial septum.", "xrefs" : [ "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:263152" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000362", "lbl" : "transitional myocyte of interventricular septum", "type" : "CLASS", "meta" : { "definition" : { "val" : "A transitional myocyte that is part of the interventricular septum.", "xrefs" : [ "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:263154" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000376", "lbl" : "Purkinje myocyte of interventricular septum", "type" : "CLASS", "meta" : { "definition" : { "val" : "A Purkinje myocyte that is part of the interventricular septum.", "xrefs" : [ "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:263182" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000409", "lbl" : "myocyte of sinoatrial node", "type" : "CLASS", "meta" : { "definition" : { "val" : "A muscle cell that is part of the sinoatrial node.", "xrefs" : [ "FMA:67102", "GOC:tfm" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "SA nodal myocyte", "xrefs" : [ "FMA:67102" ] }, { "pred" : "hasExactSynonym", "val" : "SA node cardiac muscle cell", "xrefs" : [ "GOC:pr" ] }, { "pred" : "hasExactSynonym", "val" : "sinoatrial node cell", "xrefs" : [ "GOC:pr" ] }, { "pred" : "hasExactSynonym", "val" : "sinoatrial node myocyte" }, { "pred" : "hasExactSynonym", "val" : "sinuatrial node myocyte", "xrefs" : [ "FMA:67102" ] } ], "xrefs" : [ { "val" : "FMA:67102" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000410", "lbl" : "myocyte of atrioventricular node", "type" : "CLASS", "meta" : { "definition" : { "val" : "A muscle cell that is part of the atrioventricular node.", "xrefs" : [ "FMA:67106", "GOC:tfm" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "AV nodal myocyte", "xrefs" : [ "FMA:67106" ] }, { "pred" : "hasExactSynonym", "val" : "AV node cardiac muscle cell", "xrefs" : [ "GOC:pr" ] }, { "pred" : "hasExactSynonym", "val" : "AV node cell", "xrefs" : [ "GOC:pr" ] }, { "pred" : "hasExactSynonym", "val" : "atrioventricular node cell", "xrefs" : [ "GOC:pr" ] }, { "pred" : "hasExactSynonym", "val" : "atrioventricular node myocyte", "xrefs" : [ "FMA:67106" ] } ], "xrefs" : [ { "val" : "FMA:67106" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000412", "lbl" : "endothelial cell of arteriole", "type" : "CLASS", "meta" : { "definition" : { "val" : "An endothelial cell that is part of the arteriole.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "FMA:67760" }, { "val" : "KUPO:0001097" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000413", "lbl" : "endothelial cell of artery", "type" : "CLASS", "meta" : { "definition" : { "val" : "A blood vessel endothelial cell that is part of an arterial endothelium.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "arterial endothelial cell" } ], "xrefs" : [ { "val" : "BTO:0004758" }, { "val" : "FMA:67761" }, { "val" : "KUPO:0001095" }, { "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000413" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000414", "lbl" : "endothelial cell of venule", "type" : "CLASS", "meta" : { "definition" : { "val" : "An endothelial cell that is part of the venule.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "FMA:67762" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000428", "lbl" : "stem cell of epidermis", "type" : "CLASS", "meta" : { "definition" : { "val" : "A somatic stem cell that is part of the epidermis.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epidermal stem cell", "xrefs" : [ "FMA:70541" ] } ], "xrefs" : [ { "val" : "FMA:70541" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000443", "lbl" : "ciliary muscle cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A smooth muscle cell that is part of the ciliary body.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "smooth muscle cell of ciliary body", "xrefs" : [ "FMA:70610" ] } ], "xrefs" : [ { "val" : "FMA:70610" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000444", "lbl" : "mesothelial cell of anterior chamber of eye", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mesothelial cell that is part of the anterior chamber of eyeball.", "xrefs" : [ "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:70615" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000456", "lbl" : "mesothelial cell of parietal peritoneum", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mesothelial cell that is part of the parietal peritoneum.", "xrefs" : [ "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:72142" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000457", "lbl" : "mesothelial cell of visceral peritoneum", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mesothelial cell that is part of the visceral peritoneum.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "FMA:72143" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000478", "lbl" : "transitional myocyte of sinoatrial node", "type" : "CLASS", "meta" : { "definition" : { "val" : "A transitional myocyte that is part of the sinoatrial node.", "xrefs" : [ "GOC:tfm" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "transitinal myocyte of sinuatrial node" } ], "xrefs" : [ { "val" : "FMA:83384" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000479", "lbl" : "Purkinje myocyte of atrioventricular node", "type" : "CLASS", "meta" : { "definition" : { "val" : "A Purkinje myocyte that is part of the atrioventricular node.", "xrefs" : [ "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:83386" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000482", "lbl" : "myocardial endocrine cell of interventricular septum", "type" : "CLASS", "meta" : { "definition" : { "val" : "A myocardial endocrine cell that is part of the interventricular septum.", "xrefs" : [ "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:83390" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000490", "lbl" : "mesothelial cell of peritoneum", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mesothelial cell that is part of the peritoneum.", "xrefs" : [ "GOC:tfm" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "peritoneal mesothelial cell", "xrefs" : [ "FMA:86736" ] } ], "xrefs" : [ { "val" : "FMA:86736" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000491", "lbl" : "mesothelial cell of pleura", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mesothelial cell that is part of the pleura.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "pleural mesothelial cell", "xrefs" : [ "FMA:86737" ] } ], "xrefs" : [ { "val" : "FMA:86737" }, { "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000491" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000492", "lbl" : "mesothelial cell of parietal pleura", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mesothelial cell that is part of the parietal pleura.", "xrefs" : [ "GOC:tfm" ] }, "xrefs" : [ { "val" : "FMA:86738" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000493", "lbl" : "mesothelial cell of visceral pleura", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mesothelial cell that is part of the visceral pleura.", "xrefs" : [ "GOC:tfm" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "FMA:86739" }, { "val" : "https://cellxgene.cziscience.com/cellguide/CL_1000493" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1001567", "lbl" : "lung endothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any endothelial cell of vascular tree that is part of some lung.", "xrefs" : [ "FBC:Autogenerated" ] }, "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "endothelial cell of lung" }, { "pred" : "hasRelatedSynonym", "val" : "pulmonary vessel endothelial cell" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1001568", "lbl" : "pulmonary artery endothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any endothelial cell of vascular tree that is part of some pulmonary artery.", "xrefs" : [ "FBC:Autogenerated" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "PAEC cell", "xrefs" : [ "BTO:0001141" ] } ], "xrefs" : [ { "val" : "BTO:0001141" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1001576", "lbl" : "oral mucosa squamous cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Squamous cell of oral epithelium.", "xrefs" : [ "NPX:PDR" ] }, "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "oral cavity mucosa squamous cell", "xrefs" : [ "CALOHA:TS-1252" ] }, { "pred" : "hasRelatedSynonym", "val" : "oral cavity mucosa squamous epithelial cell", "xrefs" : [ "CALOHA:TS-1252" ] }, { "pred" : "hasRelatedSynonym", "val" : "oral mucosa squamous epithelial cell", "xrefs" : [ "CALOHA:TS-1252" ] }, { "pred" : "hasRelatedSynonym", "val" : "oral mucosa squamous epithelial cells", "xrefs" : [ "CALOHA:TS-1252" ] } ], "xrefs" : [ { "val" : "CALOHA:TS-1252" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1001579", "lbl" : "cerebral cortex glial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Glial cell of cerebral cortex.", "xrefs" : [ "NPX:PDR" ] }, "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "brain cortex glial cell", "xrefs" : [ "CALOHA:TS-1256" ] }, { "pred" : "hasRelatedSynonym", "val" : "cerebral cortex glial cells", "xrefs" : [ "CALOHA:TS-1256" ] }, { "pred" : "hasRelatedSynonym", "val" : "cerebrum cortex glial cell", "xrefs" : [ "CALOHA:TS-1256" ] } ], "xrefs" : [ { "val" : "CALOHA:TS-1256" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1001602", "lbl" : "cerebral cortex endothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A distinct endothelial cell forming the walls of the capillaries within the cerebral cortex.", "xrefs" : [ "NPX:PDR" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "cerebral cortex endothelial cells", "xrefs" : [ "CALOHA:TS-2372" ] }, { "pred" : "hasRelatedSynonym", "val" : "endothelial cells of cerebral cortex", "xrefs" : [ "CALOHA:TS-2372" ] } ], "xrefs" : [ { "val" : "CALOHA:TS-2372" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1001609", "lbl" : "muscle fibroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "Fibroblast from muscle organ.", "xrefs" : [ "NPX:PDR" ] }, "xrefs" : [ { "val" : "CALOHA:TS-0643" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_1001610", "lbl" : "bone marrow hematopoietic cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Hematopoietic cells resident in the bone marrow. Include: hematopoietic stem cells (lymphoid stem cells and myeloid stem cells) and the precursor cells for thrombocytes, erythrocytes, basophils, neutrophils, eosinophils, monocytes and lymphocytes.", "xrefs" : [ "NPX:PDR" ] }, "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "bone marrow hematopoietic cells", "xrefs" : [ "CALOHA:TS-2109" ] }, { "pred" : "hasRelatedSynonym", "val" : "bone marrow poietic cells", "xrefs" : [ "CALOHA:TS-2109" ] } ], "xrefs" : [ { "val" : "CALOHA:TS-2109" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000001", "lbl" : "peripheral blood mononuclear cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood.", "xrefs" : [ "GOC:TermGenie" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-02-11T17:29:04Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000005", "lbl" : "brain macroglial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any macroglial cell that is part of a brain.", "xrefs" : [ "GOC:TermGenie" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-03-28T21:35:27Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000008", "lbl" : "microvascular endothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any blood vessel endothelial cell that is part of a microvascular endothelium.", "xrefs" : [ "GOC:TermGenie" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-06-04T15:07:42Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000010", "lbl" : "dermis blood vessel endothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any blood vessel endothelial cell that is part of a dermis.", "xrefs" : [ "GOC:TermGenie" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-06-04T15:12:06Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000013", "lbl" : "fibroblast of skin of abdomen", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any skin fibroblast that is part of a skin of abdomen.", "xrefs" : [ "GOC:TermGenie" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-06-04T15:18:16Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000016", "lbl" : "lung microvascular endothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any lung endothelial cell that is part of a microvascular endothelium.", "xrefs" : [ "GOC:TermGenie" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-06-04T16:00:56Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000019", "lbl" : "compound eye photoreceptor cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any photoreceptor cell that is part of a compound eye.", "xrefs" : [ "GOC:TermGenie" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-06-24T23:16:45Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000020", "lbl" : "inner cell mass cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any native cell that is part of a inner cell mass.", "xrefs" : [ "GOC:TermGenie" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-06-24T23:16:53Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000022", "lbl" : "cardiac septum cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any native cell that is part of a cardiac septum.", "xrefs" : [ "GOC:TermGenie" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-06-24T23:17:07Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000025", "lbl" : "spinal cord oligodendrocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any oligodendrocyte that is part of a spinal cord.", "xrefs" : [ "GOC:TermGenie" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-06-25T00:23:50Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000029", "lbl" : "central nervous system neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any neuron that is part of a central nervous system.", "xrefs" : [ "GOC:TermGenie" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-06-25T01:17:43Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000032", "lbl" : "peripheral nervous system neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuron that is part of a peripheral nervous system.", "xrefs" : [ "GOC:TermGenie", "ISBN:0721662544" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "PNS neuron" }, { "pred" : "hasExactSynonym", "val" : "peripheral neuron" } ], "xrefs" : [ { "val" : "FMA:84664" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-06-25T02:28:17Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000042", "lbl" : "embryonic fibroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any fibroblast that is part of a embryo.", "xrefs" : [ "GOC:TermGenie" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-07-09T00:12:00Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000044", "lbl" : "brain microvascular endothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any microvascular endothelial cell that is part of a brain.", "xrefs" : [ "GOC:TermGenie" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-07-09T00:24:53Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000046", "lbl" : "ventricular cardiac muscle cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any cardiac muscle cell that is part of a cardiac ventricle.", "xrefs" : [ "GOC:TermGenie" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-08-12T20:50:28Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000047", "lbl" : "brainstem motor neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any motor neuron that is part of a brainstem.", "xrefs" : [ "GOC:TermGenie" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-10-02T23:52:53Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000063", "lbl" : "ovarian fibroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any fibroblast that is part of a female gonad.", "xrefs" : [ "GOC:TermGenie" ] }, "comments" : [ "http://www.sciencellonline.com/site/productInformation.php?keyword=7330" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-10-07T17:57:42Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000064", "lbl" : "ovarian surface epithelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any epithelial cell that is part of a female gonad.", "xrefs" : [ "GOC:TermGenie" ] }, "comments" : [ "http://www.sciencellonline.com/site/productInformation.php?keyword=7310" ], "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-10-07T17:59:13Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000066", "lbl" : "cardiac ventricle fibroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any fibroblast that is part of a cardiac ventricle.", "xrefs" : [ "GOC:TermGenie" ] }, "comments" : [ "http://www.sciencellonline.com/site/productInformation.php?keyword=6310" ], "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-10-07T18:35:38Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000067", "lbl" : "cardiac atrium fibroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any fibroblast that is part of a cardiac atrium.", "xrefs" : [ "GOC:TermGenie" ] }, "comments" : [ "http://www.sciencellonline.com/site/productInformation.php?keyword=6320" ], "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-10-07T18:36:54Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000068", "lbl" : "pericardium fibroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any fibroblast that is part of a pericardium.", "xrefs" : [ "GOC:TermGenie" ] }, "comments" : [ "http://www.sciencellonline.com/site/productInformation.php?keyword=6430" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-10-07T18:38:06Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000070", "lbl" : "optic choroid fibroblast", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any fibroblast that is part of a optic choroid.", "xrefs" : [ "GOC:TermGenie" ] }, "comments" : [ "http://www.sciencellonline.com/site/productInformation.php?keyword=6620" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-10-07T18:50:43Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000072", "lbl" : "adipose microvascular endothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any microvascular endothelial cell that is part of a adipose tissue.", "xrefs" : [ "GOC:TermGenie" ] }, "comments" : [ "http://www.sciencellonline.com/site/productInformation.php?keyword=7200" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-10-07T22:13:45Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000073", "lbl" : "migratory cardiac neural crest cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any migratory neural crest cell that is part of a cardiac neural crest.", "xrefs" : [ "GOC:TermGenie" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cardiac neural crest cell", "xrefs" : [ "PMID:33060096" ] } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-11-05T01:18:43Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_2000080", "lbl" : "mesenchymal stem cell of abdominal adipose tissue", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any mesenchymal stem cell of adipose tissue that is part of an abdomen.", "xrefs" : [ "GOC:TermGenie" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesenchymal stem cell of abdominal adipose" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q35563349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-12-02T19:10:34Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_3000000", "lbl" : "ciliated epithelial cell of esophagus", "type" : "CLASS", "meta" : { "definition" : { "val" : "A ciliated epithelial cell of the esophagus.", "xrefs" : [ "GOC:CellBLAST", "PMID:29802404" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q97529981" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2019-02-09T16:40:30Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_3000004", "lbl" : "peripheral sensory neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "Peripheral sensory neuron.", "xrefs" : [ "GOC:CellBLAST", "PMID:30096314" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://www.wikidata.org/entity/Q97529981" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2019-02-25T19:34:33Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4023066", "lbl" : "horizontal pyramidal neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A pyramidal neuron which has an apical tree which is oriented parallel to the pia. This is unlike typical pyramidal neurons which have its apical dendrite aligned vertically.", "xrefs" : [ "PMID:30715238" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#BDS_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-7258-9596" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4023072", "lbl" : "brain vascular cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell that is part of the brain vasculature.", "xrefs" : [ "DOI:10.1101/2022.10.12.511898" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://orcid.org/0000-0001-7258-9596" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4023077", "lbl" : "bitufted neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A type of interneuron that has two clusters of dendritic branches that originate directly from the soma and extend in opposite directions and axons that form a plexus which spreads widely. Compared to bipolar neurons, bitufted neurons have branching that occur close to the soma.", "xrefs" : [ "PMID:18568015" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#BDS_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-7258-9596" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4023079", "lbl" : "midbrain-derived inhibitory neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A GABAergic inhibitory neuron that is derived from the midbrain.", "xrefs" : [ "DOI:10.1101/2022.10.12.511898" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://orcid.org/0000-0001-7258-9596" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4023092", "lbl" : "inverted pyramidal neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A pyramidal neuron which has an apical tree which is oriented towards the white matter.", "xrefs" : [ "PMID:30715238" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#BDS_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-7258-9596" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4023093", "lbl" : "stellate pyramidal neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A pyramidal neuron which lacks a tuft formation but extends small radial distances forming a star-like shape.", "xrefs" : [ "PMID:30715238" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#BDS_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-7258-9596" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4023094", "lbl" : "tufted pyramidal neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A pyramidal neuron which has a distinctive tuft formation, distal from the soma.", "xrefs" : [ "PMID:30715238" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#BDS_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-7258-9596" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4023095", "lbl" : "untufted pyramidal neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A pyramidal neuron which lacks a clear tuft formation but extends to large radial distances.", "xrefs" : [ "PMID:30715238" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#BDS_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-7258-9596" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4023111", "lbl" : "cerebral cortex pyramidal neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A pyramidal neuron with soma located in the cerebral cortex.", "xrefs" : [ "PMID:30715238" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-7258-9596" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4023154", "lbl" : "myelinating glial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A glial cell that myelinates axonal processes.", "xrefs" : [ "DOI:10.1007/3-540-29623-9_3240" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-7258-9596" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4023159", "lbl" : "double bouquet cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "An interneuron that has double bouquet morphology.", "xrefs" : [ "PMID:15378039" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://orcid.org/0000-0001-7258-9596" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4023168", "lbl" : "somatosensory neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuron that is part of the somatic sensory system. Somatosensory neurons innervate the skin or integument to detect different types of thermal, chemical, and mechanical touch stimuli.", "xrefs" : [ "PMID:22865660" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "http://orcid.org/0000-0001-7258-9596" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4028001", "lbl" : "pulmonary capillary endothelial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any capillary endothelial cell that is part of a lung." }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "lung capillary endothelial cell" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0002-3293-5463" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2021-11-23T02:31:40Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4030029", "lbl" : "blood lymphocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "A lymphocyte located in blood.", "xrefs" : [ "https://orcid.org/0000-0001-9990-8331" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/date", "val" : "2022-11-04T14:40:00Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4030034", "lbl" : "respiratory ciliated cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A ciliated cell of the respiratory system. Ciliated cells are present in airway epithelium.", "xrefs" : [ "PMID:18757316", "PMID:21364219" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "ciliated cell of the respiratory tract" } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/date", "val" : "2023-01-25T11:06:01Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4033008", "lbl" : "vein endothelial cell of respiratory system", "type" : "CLASS", "meta" : { "definition" : { "val" : "A(n) vein endothelial cell that is part of a(n) respiratory system.", "xrefs" : [ "PMID:34030460" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-6677-8489" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4033018", "lbl" : "lung megakaryocyte", "type" : "CLASS", "meta" : { "definition" : { "val" : "A megakaryocyte that is resident in the lung connective tissue.", "xrefs" : [ "PMID:33351116" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "lung resident megakaryocyte", "xrefs" : [ "PMID:36524131" ] }, { "pred" : "hasExactSynonym", "val" : "lung-resident megakaryocyte", "xrefs" : [ "PMID:36524131" ] } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-6677-8489" }, { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0002-9185-3994" }, { "pred" : "http://purl.org/dc/terms/date", "val" : "2023-03-16T11:31:23Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4033049", "lbl" : "taste receptor cell of tongue", "type" : "CLASS", "meta" : { "definition" : { "val" : "A taste receptor cell that is part of a taste bud of a tongue.", "xrefs" : [ "DOI:10.1111/j.1096-3642.1981.tb01137.x", "PMID:10052456", "PMID:28655883", "http://www.nejohnston.org/Birds/documents/AvianTongues_Johnston.pdf" ] }, "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "gustatory cell of tongue", "xrefs" : [ "DOI:10.1016/s0022-5320(69)80043-2" ] } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-6677-8489" }, { "pred" : "http://purl.org/dc/terms/date", "val" : "2023-05-03T07:59:58Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4033050", "lbl" : "catecholaminergic neuron", "type" : "CLASS", "meta" : { "definition" : { "val" : "A neuron that releases catecholamine as a neurotransmitter.", "xrefs" : [ "ISBN:0521442516", "PMID:12094209" ] }, "comments" : [ "Frequently used when describing the developing nervous system in zebrafish. A catecholaminergic neuron expresses tyrosine hydroxylase (TH), tyrosine hydroxylase 2 (TH2), aromatic amino acid decarboxylase (AADC), dopamine b-hydroxylase (DBH), and phenylethanolamine-N-methyl transferase (PEMT), which are enzymes necessary for catecholamine synthesis." ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-6677-8489" }, { "pred" : "http://purl.org/dc/terms/date", "val" : "2023-05-18T12:07:45Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4033054", "lbl" : "perivascular cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell that is adjacent to a vessel. A perivascular cell plays a crucial role in maintaining vascular function and tissue homeostasis. This cell type regulates vessel integrity and flow dynamics.", "xrefs" : [ "PMID:24928499", "PMID:27889329" ] }, "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-6677-8489" }, { "pred" : "http://purl.org/dc/terms/date", "val" : "2023-08-22T13:40:28Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4033081", "lbl" : "cycling myeloid cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A(n) myeloid cell that is cycling.", "xrefs" : [ "PMID:38301653" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "proliferating myeloid cell", "xrefs" : [ "PMID:38301653" ] } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-6677-8489" }, { "pred" : "http://purl.org/dc/terms/date", "val" : "2024-07-02T09:14:23Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4040004", "lbl" : "mesenchymal stem cell of orbital adipose tissue", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any mesenchymal stem cell of adipose tissue that is part of an orbital region.", "xrefs" : [ "https://orcid.org/0000-0002-0819-0473" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "OAMSC", "xrefs" : [ "PMID:31377878" ] }, { "pred" : "hasExactSynonym", "val" : "Orbital ASCs", "xrefs" : [ "PMID:30210548" ] }, { "pred" : "hasExactSynonym", "val" : "orbital adipose-derived mesenchymal stem cell", "xrefs" : [ "PMID:31377878" ] } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0002-0819-0473" }, { "pred" : "http://purl.org/dc/terms/date", "val" : "2023-09-18T10:43:00Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4047001", "lbl" : "cycling stromal cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A(n) stromal cell that is cycling.", "xrefs" : [ "PMID:34497389" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "proliferating stromal cell", "xrefs" : [ "PMID:34497389" ] } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0009-0005-7919-4905" }, { "pred" : "http://purl.org/dc/terms/date", "val" : "2024-07-19T09:14:23Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4047002", "lbl" : "cycling glial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A(n) glial cell that is cycling.", "xrefs" : [ "PMID:34497389" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "proliferating glial cell", "xrefs" : [ "PMID:34497389" ] } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0009-0005-7919-4905" }, { "pred" : "http://purl.org/dc/terms/date", "val" : "2024-07-19T09:14:23Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4047005", "lbl" : "cycling neuroblast (sensu Vertebrata)", "type" : "CLASS", "meta" : { "definition" : { "val" : "A(n) neuroblast (sensu Vertebrata) that is cycling.", "xrefs" : [ "PMID:34497389" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "proliferating neuroblast (sensu Vertebrata)", "xrefs" : [ "PMID:34497389" ] } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0009-0005-7919-4905" }, { "pred" : "http://purl.org/dc/terms/date", "val" : "2024-07-19T09:14:23Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_4052002", "lbl" : "syncytial cell", "type" : "CLASS", "meta" : { "definition" : { "val" : "A multinucleate cell formed by the fusion of multiple uninuclear cells through plasma membrane fusion. This process leads to a single large cell containing multiple nuclei within a shared cytoplasm.", "xrefs" : [ "PMID:20851884", "Wikipedia:Syncytium" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "syncytium", "xrefs" : [ "WBbt:0008074" ] } ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0009-0000-8480-9277" }, { "pred" : "http://purl.org/dc/terms/date", "val" : "2024-08-15T10:38:46Z" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000011", "lbl" : "vacuole inheritance", "type" : "CLASS", "meta" : { "definition" : { "val" : "The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton.", "xrefs" : [ "GOC:mcc", "PMID:10873824", "PMID:14616069" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000070", "lbl" : "mitotic sister chromatid segregation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.", "xrefs" : [ "GOC:ai", "GOC:jl" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pombe" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mitotic chromosome segregation" }, { "pred" : "hasNarrowSynonym", "val" : "mitotic sister-chromatid adhesion release" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0016359" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000139", "lbl" : "Golgi membrane", "type" : "CLASS", "meta" : { "definition" : { "val" : "The lipid bilayer surrounding any of the compartments of the Golgi apparatus.", "xrefs" : [ "GOC:mah" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Golgi apparatus membrane" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000226", "lbl" : "microtubule cytoskeleton organization", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.", "xrefs" : [ "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pombe" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "microtubule cytoskeleton organisation", "xrefs" : [ "GOC:mah" ] }, { "pred" : "hasRelatedSynonym", "val" : "microtubule cytoskeleton organization and biogenesis", "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000228", "lbl" : "nuclear chromosome", "type" : "CLASS", "meta" : { "definition" : { "val" : "A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.", "xrefs" : [ "GOC:dph", "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "nuclear interphase chromosome" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000271", "lbl" : "polysaccharide biosynthetic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.", "xrefs" : [ "GOC:go_curators" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "glycan biosynthesis" }, { "pred" : "hasExactSynonym", "val" : "glycan biosynthetic process" }, { "pred" : "hasExactSynonym", "val" : "polysaccharide anabolism" }, { "pred" : "hasExactSynonym", "val" : "polysaccharide biosynthesis" }, { "pred" : "hasExactSynonym", "val" : "polysaccharide formation" }, { "pred" : "hasExactSynonym", "val" : "polysaccharide synthesis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000278", "lbl" : "mitotic cell cycle", "type" : "CLASS", "meta" : { "definition" : { "val" : "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.", "xrefs" : [ "GOC:mah", "ISBN:0815316194" ] }, "comments" : [ "Note that this term should not be confused with 'GO:0140014 ; mitotic nuclear division'. 'GO:0000278 ; mitotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140014 ; mitotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "mitosis" } ], "xrefs" : [ { "val" : "Wikipedia:Mitosis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0007067" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000280", "lbl" : "nuclear division", "type" : "CLASS", "meta" : { "definition" : { "val" : "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.", "xrefs" : [ "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "karyokinesis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000313", "lbl" : "organellar ribosome", "type" : "CLASS", "meta" : { "definition" : { "val" : "A ribosome contained within a subcellular membrane-bounded organelle.", "xrefs" : [ "GOC:mah", "GOC:mcc" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000740", "lbl" : "nuclear membrane fusion", "type" : "CLASS", "meta" : { "definition" : { "val" : "The joining of 2 or more lipid bilayer membranes that surround the nucleus.", "xrefs" : [ "GOC:elh" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000741", "lbl" : "karyogamy", "type" : "CLASS", "meta" : { "definition" : { "val" : "The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei.", "xrefs" : [ "GOC:elh" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "nuclear fusion" }, { "pred" : "hasExactSynonym", "val" : "nuclear fusion during karyogamy" } ], "xrefs" : [ { "val" : "Wikipedia:Karyogamy" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0007335" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000768", "lbl" : "syncytium formation by plasma membrane fusion", "type" : "CLASS", "meta" : { "definition" : { "val" : "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.", "xrefs" : [ "GOC:mtg_muscle", "GOC:tb" ] }, "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cell fusion" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000785", "lbl" : "chromatin", "type" : "CLASS", "meta" : { "definition" : { "val" : "The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.", "xrefs" : [ "GOC:elh", "PMID:20404130" ] }, "comments" : [ "Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore." ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "cytoplasmic chromatin" }, { "pred" : "hasNarrowSynonym", "val" : "nuclear chromatin" }, { "pred" : "hasRelatedSynonym", "val" : "chromosome scaffold" } ], "xrefs" : [ { "val" : "NIF_Subcellular:sao1615953555" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0000789" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0000790" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0005717" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000792", "lbl" : "heterochromatin", "type" : "CLASS", "meta" : { "definition" : { "val" : "A compact and highly condensed form of chromatin that is refractory to transcription.", "xrefs" : [ "PMID:32017156" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "transcriptionally inactive chromatin" }, { "pred" : "hasExactSynonym", "val" : "transcriptionally silent chromatin" }, { "pred" : "hasNarrowSynonym", "val" : "nuclear heterochromatin" } ], "xrefs" : [ { "val" : "NIF_Subcellular:sao581845896" }, { "val" : "Wikipedia:Heterochromatin" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0005720" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0035328" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000819", "lbl" : "sister chromatid segregation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets.", "xrefs" : [ "GOC:ai", "GOC:elh" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000902", "lbl" : "cell morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The developmental process in which the size or shape of a cell is generated and organized.", "xrefs" : [ "GOC:clt", "GOC:dph", "GOC:go_curators", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cellular morphogenesis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0007148" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0045790" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0045791" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001101", "lbl" : "response to acid chemical", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.", "xrefs" : [ "GOC:go_curators", "GOC:rn" ] }, "comments" : [ "This term should be used to describe a response to a specific acid as a chemical. E.g., if an organism were responding to glutamate, then the response would be glutamate-specific; the organism is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0010447 'response to acidic pH' instead." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "response to acid" }, { "pred" : "hasRelatedSynonym", "val" : "response to acid anion" }, { "pred" : "hasRelatedSynonym", "val" : "response to oxoanion" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001501", "lbl" : "skeletal system development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).", "xrefs" : [ "GOC:dph", "GOC:jid", "GOC:tb" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "skeletal development" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001503", "lbl" : "ossification", "type" : "CLASS", "meta" : { "definition" : { "val" : "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.", "xrefs" : [ "GOC:mtg_mpo", "PMID:17572649" ] }, "comments" : [ "Note that this term does not have a 'developmental process' parent because ossification isn't necessarily developmental, can also occur as part of bone remodeling. Instead use 'ossification involved in bone maturation ; GO:0043931'." ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "bone biosynthesis" }, { "pred" : "hasExactSynonym", "val" : "bone formation" }, { "pred" : "hasExactSynonym", "val" : "osteogenesis" } ], "xrefs" : [ { "val" : "Wikipedia:Ossification" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001508", "lbl" : "action potential", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.", "xrefs" : [ "GOC:dph", "GOC:go_curators", "GOC:tb", "ISBN:978-0-07-139011-8" ] }, "comments" : [ "Action potentials typically propagate across excitable membranes. This class covers both action potentials that propagate and those that fail to do so." ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001525", "lbl" : "angiogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.", "xrefs" : [ "ISBN:0878932453" ] }, "xrefs" : [ { "val" : "Wikipedia:Angiogenesis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001539", "lbl" : "cilium or flagellum-dependent cell motility", "type" : "CLASS", "meta" : { "definition" : { "val" : "Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella.", "xrefs" : [ "GOC:cilia", "GOC:hjd", "GOC:krc" ] }, "comments" : [ "Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent, while the bacterial- and archaeal-type flagella have a different structure. The former are microtubule-based structures that lash back and forth and are present only in eukaryotes, while the latter achieve motility by rotation. Bacterial- and archaeal-type flagella are superficially similar but have a different molecular composition and fine structure. These three structures never co-exist in the same organism. Therefore, GO:0001539 'cilium or flagellum-dependent cell motility' is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term. Direct annotations to GO:0001539 'cilium or flagellum-dependent cell motility' may be amended during annotation QC." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "ciliary/flagellar motility" }, { "pred" : "hasRelatedSynonym", "val" : "ciliary or bacterial-type flagellar motility" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001555", "lbl" : "oocyte growth", "type" : "CLASS", "meta" : { "definition" : { "val" : "The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.", "xrefs" : [ "https://www.ncbi.nlm.nih.gov/books/NBK279054/" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001556", "lbl" : "oocyte maturation", "type" : "CLASS", "meta" : { "definition" : { "val" : "A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.", "xrefs" : [ "GOC:devbiol", "https://www.ncbi.nlm.nih.gov/books/NBK279054/" ] }, "xrefs" : [ { "val" : "Wikipedia:Oocyte_maturation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001558", "lbl" : "regulation of cell growth", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate, extent or direction of cell growth.", "xrefs" : [ "GOC:go_curators" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001560", "lbl" : "regulation of cell growth by extracellular stimulus", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time.", "xrefs" : [ "GOC:dph" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "interpretation of external signals that regulate cell growth" }, { "pred" : "hasExactSynonym", "val" : "regulation of cell growth by detection of exogenous stimulus" }, { "pred" : "hasExactSynonym", "val" : "regulation of cell growth by sensing of exogenous stimulus" }, { "pred" : "hasExactSynonym", "val" : "regulation of growth by exogenous signal" }, { "pred" : "hasExactSynonym", "val" : "regulation of growth by exogenous stimuli" }, { "pred" : "hasExactSynonym", "val" : "regulation of growth by exogenous stimulus" }, { "pred" : "hasExactSynonym", "val" : "regulation of growth by external signal" }, { "pred" : "hasExactSynonym", "val" : "regulation of growth by external stimuli" }, { "pred" : "hasExactSynonym", "val" : "regulation of growth by external stimulus" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001568", "lbl" : "blood vessel development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.", "xrefs" : [ "GOC:hjd", "UBERON:0001981" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001569", "lbl" : "branching involved in blood vessel morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system.", "xrefs" : [ "GOC:dph" ] }, "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "patterning of blood vessels", "xrefs" : [ "GOC:dph" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001570", "lbl" : "vasculogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes.", "xrefs" : [ "PMID:8999798" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "vascular morphogenesis" } ], "xrefs" : [ { "val" : "Wikipedia:Vasculogenesis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001578", "lbl" : "microtubule bundle formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process that results in a parallel arrangement of microtubules.", "xrefs" : [ "GOC:dph" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "microtubule bundling" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001654", "lbl" : "eye development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.", "xrefs" : [ "GOC:jid", "GOC:jl" ] }, "xrefs" : [ { "val" : "Wikipedia:Eye_development" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0042460" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001659", "lbl" : "temperature homeostasis", "type" : "CLASS", "meta" : { "definition" : { "val" : "A homeostatic process in which an organism modulates its internal body temperature.", "xrefs" : [ "GOC:jl" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "thermoregulation", "xrefs" : [ "GOC:dph", "GOC:tb" ] } ], "xrefs" : [ { "val" : "Wikipedia:Thermoregulation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001666", "lbl" : "response to hypoxia", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.", "xrefs" : [ "GOC:hjd" ] }, "comments" : [ "Note that this term should not be confused with 'response to anoxia ; GO:0034059'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%." ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "response to hypoxic stress" }, { "pred" : "hasExactSynonym", "val" : "response to lowered oxygen tension" }, { "pred" : "hasNarrowSynonym", "val" : "response to intermittent hypoxia" }, { "pred" : "hasNarrowSynonym", "val" : "response to sustained hypoxia" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001667", "lbl" : "ameboidal-type cell migration", "type" : "CLASS", "meta" : { "definition" : { "val" : "Cell migration that is accomplished by extension and retraction of a pseudopodium.", "xrefs" : [ "GOC:dph" ] }, "comments" : [ "Note that this term refers to a mode of migration rather than to any particular cell type." ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "ameboid cell migration" }, { "pred" : "hasExactSynonym", "val" : "amoeboid cell migration" }, { "pred" : "hasExactSynonym", "val" : "amoeboidal cell migration" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001674", "lbl" : "female germ cell nucleus", "type" : "CLASS", "meta" : { "definition" : { "val" : "The nucleus of the female germ cell, a reproductive cell in females.", "xrefs" : [ "CL:0000021", "GOC:hjd" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "female germ-cell nucleus" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0043080" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001677", "lbl" : "formation of translation initiation ternary complex", "type" : "CLASS", "meta" : { "definition" : { "val" : "Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).", "xrefs" : [ "GOC:hjd" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "translation initiation ternary complex assembly" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001696", "lbl" : "gastric acid secretion", "type" : "CLASS", "meta" : { "definition" : { "val" : "The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.", "xrefs" : [ "GOC:hjd" ] }, "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "hydrochloric acid secretion" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001700", "lbl" : "embryonic development via the syncytial blastoderm", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster.", "xrefs" : [ "GOC:go_curators", "GOC:mtg_sensu" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001701", "lbl" : "in utero embryonic development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.", "xrefs" : [ "GOC:go_curators", "GOC:mtg_sensu" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001704", "lbl" : "formation of primary germ layer", "type" : "CLASS", "meta" : { "definition" : { "val" : "The formation of the ectoderm, mesoderm and endoderm during gastrulation.", "xrefs" : [ "GOC:go_curators" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001705", "lbl" : "ectoderm formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The formation of ectoderm during gastrulation.", "xrefs" : [ "GOC:go_curators" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001706", "lbl" : "endoderm formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The formation of the endoderm during gastrulation.", "xrefs" : [ "GOC:go_curators" ] }, "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "endoblast formation", "xrefs" : [ "GOC:dph", "GOC:sdb_2009", "GOC:tb" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001707", "lbl" : "mesoderm formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts.", "xrefs" : [ "GOC:go_curators" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001743", "lbl" : "lens placode formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The initial developmental process that will lead to the formation of an eye.", "xrefs" : [ "GOC:dph" ] }, "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "optic placode formation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001745", "lbl" : "compound eye morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.", "xrefs" : [ "GOC:dph", "GOC:mtg_sensu" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "insect-type retina morphogenesis", "xrefs" : [ "PMID:11735386" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001751", "lbl" : "compound eye photoreceptor cell differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell.", "xrefs" : [ "GOC:go_curators" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001754", "lbl" : "eye photoreceptor cell differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms.", "xrefs" : [ "GOC:go_curators" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001755", "lbl" : "neural crest cell migration", "type" : "CLASS", "meta" : { "definition" : { "val" : "The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo.", "xrefs" : [ "GOC:ascb_2009", "GOC:dph", "GOC:tb", "ISBN:0878932437" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001756", "lbl" : "somitogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.", "xrefs" : [ "ISBN:0721662544" ] }, "xrefs" : [ { "val" : "Wikipedia:Somitogenesis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001763", "lbl" : "morphogenesis of a branching structure", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes.", "xrefs" : [ "ISBN:0721662544" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "branching morphogenesis", "xrefs" : [ "GOC:dph" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001764", "lbl" : "neuron migration", "type" : "CLASS", "meta" : { "definition" : { "val" : "The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature.", "xrefs" : [ "CL:0000540", "GOC:go_curators" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neuron chemotaxis" }, { "pred" : "hasExactSynonym", "val" : "neuronal migration" }, { "pred" : "hasRelatedSynonym", "val" : "neuron guidance" } ], "xrefs" : [ { "val" : "Wikipedia:Neural_development#Neuron_migration" }, { "val" : "Wikipedia:Neuron_migration" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001767", "lbl" : "establishment of lymphocyte polarity", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell.", "xrefs" : [ "GOC:mgi_curators", "PMID:11244041", "PMID:12615889" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "lymphocyte polarization" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001775", "lbl" : "cell activation", "type" : "CLASS", "meta" : { "definition" : { "val" : "A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell.", "xrefs" : [ "GOC:mgi_curators" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001776", "lbl" : "leukocyte homeostasis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus.", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, "comments" : [ "Note that this term represents the return of immune system cell levels to stable numbers following an immune response as well as the proliferation and elimination of cells of the immune system required to maintain stable numbers in the absence of an outside stimulus." ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "immune cell homeostasis" }, { "pred" : "hasExactSynonym", "val" : "leucocyte homeostasis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001820", "lbl" : "serotonin secretion", "type" : "CLASS", "meta" : { "definition" : { "val" : "The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells.", "xrefs" : [ "GOC:ef", "ISBN:0198506732", "ISBN:0781735149" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "5-HT secretion" }, { "pred" : "hasExactSynonym", "val" : "5-hydroxytryptamine secretion" }, { "pred" : "hasRelatedSynonym", "val" : "serotonin release", "xrefs" : [ "GOC:tb" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001824", "lbl" : "blastocyst development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm.", "xrefs" : [ "GOC:dph", "ISBN:0124020607", "ISBN:0198542771" ] }, "comments" : [ "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS5, embryo ; EMAP:23', 'TS5, inner cell mass ; EMAP:24' and 'TS5, trophectoderm; EMAP:28'." ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001825", "lbl" : "blastocyst formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The initial formation of a blastocyst from a solid ball of cells known as a morula.", "xrefs" : [ "GOC:dph", "ISBN:0124020607", "ISBN:0198542771" ] }, "comments" : [ "See also the Anatomical Dictionary for Mouse Development ontology term 'TS3, compacted morula ; EMAP:9'." ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001826", "lbl" : "inner cell mass cell differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell.", "xrefs" : [ "GOC:dph", "ISBN:0124020607", "ISBN:0198542771" ] }, "comments" : [ "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14'." ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001829", "lbl" : "trophectodermal cell differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell.", "xrefs" : [ "GOC:dph", "ISBN:0124020607", "ISBN:0198542771" ] }, "comments" : [ "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19'." ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "trophectoderm cell differentiation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001831", "lbl" : "trophectodermal cellular morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The morphogenesis of trophectoderm cells.", "xrefs" : [ "GOC:dph", "ISBN:0124020607", "ISBN:0198542771" ] }, "comments" : [ "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'." ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "trophectoderm cellular morphogenesis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001832", "lbl" : "blastocyst growth", "type" : "CLASS", "meta" : { "definition" : { "val" : "An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation.", "xrefs" : [ "GOC:dph", "ISBN:0124020607", "ISBN:0198542771" ] }, "comments" : [ "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, blastocoelic cavity ; EMAP:17', 'TS5, blastocoelic cavity ; EMAP:27' and 'TS6, blastocoelic cavity ; EMAP:36'." ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001833", "lbl" : "inner cell mass cell proliferation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The proliferation of cells in the inner cell mass.", "xrefs" : [ "GOC:dph", "GOC:isa_complete", "ISBN:0124020607", "ISBN:0198542771" ] }, "comments" : [ "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14' and 'TS5, inner cell mass ; EMAP:24'." ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001834", "lbl" : "trophectodermal cell proliferation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The proliferation of cells in the trophectoderm.", "xrefs" : [ "GOC:dph", "ISBN:0124020607", "ISBN:0198542771" ] }, "comments" : [ "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'." ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "trophectoderm cell proliferation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001837", "lbl" : "epithelial to mesenchymal transition", "type" : "CLASS", "meta" : { "definition" : { "val" : "A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.", "xrefs" : [ "GOC:dph", "PMID:14701881" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "EMT" }, { "pred" : "hasExactSynonym", "val" : "epithelial-mesenchymal transition" }, { "pred" : "hasExactSynonym", "val" : "mesenchymal cell differentiation from epithelial cell", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:rl" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001838", "lbl" : "embryonic epithelial tube formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The morphogenesis of an embryonic epithelium into a tube-shaped structure.", "xrefs" : [ "GOC:dph", "ISBN:0824072820" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001839", "lbl" : "neural plate morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue.", "xrefs" : [ "GOC:dph", "ISBN:0878932437" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001840", "lbl" : "neural plate development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.", "xrefs" : [ "GOC:dph", "GOC:ef", "ISBN:0878932437", "ISBN:0878932585" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001841", "lbl" : "neural tube formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system.", "xrefs" : [ "GOC:dph", "ISBN:0878932437" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neural tube morphogenesis", "xrefs" : [ "GOC:dph" ] }, { "pred" : "hasExactSynonym", "val" : "neurulation" } ], "xrefs" : [ { "val" : "Wikipedia:Neurulation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0001679" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001842", "lbl" : "neural fold formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove.", "xrefs" : [ "GOC:dph", "ISBN:0878932437" ] }, "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "neural groove formation", "xrefs" : [ "GOC:dph" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001878", "lbl" : "response to yeast", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species.", "xrefs" : [ "PMID:14707091" ] }, "comments" : [ "defined as response to Saccharomycotina (true yeasts). This excludes fission yeast." ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001885", "lbl" : "endothelial cell development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The progression of an endothelial cell over time, from its formation to the mature structure.", "xrefs" : [ "GOC:dph" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001886", "lbl" : "endothelial cell morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell.", "xrefs" : [ "GOC:ascb_2009", "GOC:dph", "GOC:tb" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001935", "lbl" : "endothelial cell proliferation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001936", "lbl" : "regulation of endothelial cell proliferation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate, or extent of endothelial cell proliferation.", "xrefs" : [ "GOC:add" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001937", "lbl" : "negative regulation of endothelial cell proliferation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of endothelial cell proliferation" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of endothelial cell proliferation" }, { "pred" : "hasExactSynonym", "val" : "downregulation of endothelial cell proliferation" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of endothelial cell proliferation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001938", "lbl" : "positive regulation of endothelial cell proliferation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the rate or extent of endothelial cell proliferation.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "up regulation of endothelial cell proliferation" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of endothelial cell proliferation" }, { "pred" : "hasExactSynonym", "val" : "upregulation of endothelial cell proliferation" }, { "pred" : "hasNarrowSynonym", "val" : "activation of endothelial cell proliferation" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of endothelial cell proliferation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001944", "lbl" : "vasculature development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.", "xrefs" : [ "GOC:dph", "UBERON:0002409" ] }, "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "vascular system development" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001955", "lbl" : "blood vessel maturation", "type" : "CLASS", "meta" : { "definition" : { "val" : "A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state.", "xrefs" : [ "GOC:dph" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001956", "lbl" : "positive regulation of neurotransmitter secretion", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter.", "xrefs" : [ "GOC:hjd" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "up regulation of neurotransmitter secretion" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of neurotransmitter secretion" }, { "pred" : "hasExactSynonym", "val" : "upregulation of neurotransmitter secretion" }, { "pred" : "hasNarrowSynonym", "val" : "activation of neurotransmitter secretion" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of neurotransmitter secretion" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001957", "lbl" : "intramembranous ossification", "type" : "CLASS", "meta" : { "definition" : { "val" : "Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells.", "xrefs" : [ "ISBN:0878932437" ] }, "comments" : [ "An instance of intramembranous ossification may also be classified as metaplastic; the former classifies based on tissue type location, and the latter based on mechanism/cell division." ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "dermal ossification", "xrefs" : [ "GO_REF:0000034" ] }, { "pred" : "hasRelatedSynonym", "val" : "intramembranous bone ossification", "xrefs" : [ "GOC:cjm" ] } ], "xrefs" : [ { "val" : "Wikipedia:Intramembranous_ossification" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002009", "lbl" : "morphogenesis of an epithelium", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.", "xrefs" : [ "GOC:dph", "GOC:jl", "GOC:tb", "ISBN:0198506732" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epithelium morphogenesis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002011", "lbl" : "morphogenesis of an epithelial sheet", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells.", "xrefs" : [ "GOC:jl" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002027", "lbl" : "regulation of heart rate", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency or rate of heart contraction.", "xrefs" : [ "GOC:dph", "GOC:tb", "PMID:10358008" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cardiac chronotropy", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, { "pred" : "hasExactSynonym", "val" : "regulation of heart contraction rate" }, { "pred" : "hasExactSynonym", "val" : "regulation of rate of heart contraction" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002052", "lbl" : "positive regulation of neuroblast proliferation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the rate of neuroblast proliferation.", "xrefs" : [ "GOC:dph" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "up regulation of neuroblast proliferation" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of neuroblast proliferation" }, { "pred" : "hasExactSynonym", "val" : "upregulation of neuroblast proliferation" }, { "pred" : "hasNarrowSynonym", "val" : "activation of neuroblast proliferation" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of neuroblast proliferation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002053", "lbl" : "positive regulation of mesenchymal cell proliferation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells.", "xrefs" : [ "GOC:dph" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "up regulation of mesenchymal cell proliferation" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of mesenchymal cell proliferation" }, { "pred" : "hasExactSynonym", "val" : "upregulation of mesenchymal cell proliferation" }, { "pred" : "hasNarrowSynonym", "val" : "activation of mesenchymal cell proliferation" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of mesenchymal cell proliferation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002062", "lbl" : "chondrocyte differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.", "xrefs" : [ "GOC:dph" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002063", "lbl" : "chondrocyte development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.", "xrefs" : [ "GOC:dph" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002064", "lbl" : "epithelial cell development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.", "xrefs" : [ "GOC:dph" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002065", "lbl" : "columnar/cuboidal epithelial cell differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.", "xrefs" : [ "GOC:dph" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002066", "lbl" : "columnar/cuboidal epithelial cell development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.", "xrefs" : [ "GOC:dph" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002067", "lbl" : "glandular epithelial cell differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.", "xrefs" : [ "GOC:dph" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002068", "lbl" : "glandular epithelial cell development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.", "xrefs" : [ "GOC:dph" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002069", "lbl" : "columnar/cuboidal epithelial cell maturation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.", "xrefs" : [ "GOC:dph" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002070", "lbl" : "epithelial cell maturation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.", "xrefs" : [ "GOC:dph" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002071", "lbl" : "glandular epithelial cell maturation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.", "xrefs" : [ "GOC:dph" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002072", "lbl" : "optic cup morphogenesis involved in camera-type eye development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus.", "xrefs" : [ "GOC:dph", "GOC:mtg_sensu", "GOC:sdb_2009", "GOC:tb", "ISBN:0878932437" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "optic cup morphogenesis involved in camera-style eye development" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002085", "lbl" : "inhibition of neuroepithelial cell differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells.", "xrefs" : [ "GOC:dph", "PMID:16678814" ] }, "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "negative regulation of neural plate formation", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, { "pred" : "hasNarrowSynonym", "val" : "repression of premature neural plate formation", "xrefs" : [ "GOC:dph", "GOC:tb" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002087", "lbl" : "regulation of respiratory gaseous exchange by nervous system process", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates.", "xrefs" : [ "GOC:dph", "GOC:tb", "PMID:12458206" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neurological control of breathing", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, { "pred" : "hasExactSynonym", "val" : "regulation of respiratory gaseous exchange by neurological system process" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002088", "lbl" : "lens development in camera-type eye", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.", "xrefs" : [ "GOC:dph", "ISBN:0582064333" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "lens development" }, { "pred" : "hasExactSynonym", "val" : "lens development in camera-style eye" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002089", "lbl" : "lens morphogenesis in camera-type eye", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.", "xrefs" : [ "GOC:dph", "GOC:mtg_sensu" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "lens morphogenesis" }, { "pred" : "hasExactSynonym", "val" : "lens morphogenesis in camera-style eye" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002181", "lbl" : "cytoplasmic translation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.", "xrefs" : [ "GOC:hjd" ] }, "comments" : [ "Note that this term applies to translation performed by cytoplasmic ribosomes, which is distinct from translation performed by organellar ribosomes. For mitochondrial translation, consider GO:0032543 'mitochondrial translation' or its child terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "hjd" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-06-09T03:11:53Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002182", "lbl" : "cytoplasmic translational elongation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm.", "xrefs" : [ "GOC:hjd" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "hjd" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-06-09T03:14:42Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002183", "lbl" : "cytoplasmic translational initiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.", "xrefs" : [ "GOC:hjd" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "hjd" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-06-09T03:15:48Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002184", "lbl" : "cytoplasmic translational termination", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon.", "xrefs" : [ "GOC:hjd" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "hjd" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-06-09T03:17:13Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002213", "lbl" : "defense response to insect", "type" : "CLASS", "meta" : { "definition" : { "val" : "A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "physiological defense response to insect" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0002214" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002244", "lbl" : "hematopoietic progenitor cell differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.", "xrefs" : [ "GOC:add", "GOC:rl", "ISBN:0781735149", "PMID:16551251" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "haematopoietic progenitor cell differentiation" }, { "pred" : "hasExactSynonym", "val" : "haemopoietic progenitor cell differentiation" }, { "pred" : "hasExactSynonym", "val" : "hemopoietic progenitor cell differentiation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002252", "lbl" : "immune effector process", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation.", "xrefs" : [ "GOC:add", "GO_REF:0000022", "ISBN:0781735149" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002260", "lbl" : "lymphocyte homeostasis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.", "xrefs" : [ "GOC:add", "PMID:15826826", "PMID:16319493", "PMID:16551252", "PMID:16551262" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002262", "lbl" : "myeloid cell homeostasis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.", "xrefs" : [ "CL:0000763", "GOC:add" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002269", "lbl" : "leukocyte activation involved in inflammatory response", "type" : "CLASS", "meta" : { "definition" : { "val" : "A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response.", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "immune cell activation during inflammatory response" }, { "pred" : "hasRelatedSynonym", "val" : "leukocyte activation during inflammatory response", "xrefs" : [ "GOC:tb" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002274", "lbl" : "myeloid leukocyte activation", "type" : "CLASS", "meta" : { "definition" : { "val" : "A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand.", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "myeloid leucocyte activation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002318", "lbl" : "myeloid progenitor cell differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages.", "xrefs" : [ "GOC:add", "PMID:16551264" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002320", "lbl" : "lymphoid progenitor cell differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages.", "xrefs" : [ "GOC:add", "PMID:16551251", "PMID:16551264" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002351", "lbl" : "serotonin production involved in inflammatory response", "type" : "CLASS", "meta" : { "definition" : { "val" : "The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.", "xrefs" : [ "GOC:add", "ISBN:0781735149", "PMID:16730260" ] }, "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "serotonin production involved in acute inflammatory response" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002376", "lbl" : "immune system process", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.", "xrefs" : [ "GOC:add", "GO_REF:0000022" ] }, "comments" : [ "Note that this term is a direct child of 'biological_process ; GO:0008150' because some immune system processes are types of cellular process (GO:0009987), whereas others are types of multicellular organism process (GO:0032501)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "xrefs" : [ { "val" : "Wikipedia:Immune_system" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002442", "lbl" : "serotonin secretion involved in inflammatory response", "type" : "CLASS", "meta" : { "definition" : { "val" : "The regulated release of serotonin by a cell as part of an inflammatory response.", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "serotonin secretion involved in acute inflammatory response" }, { "pred" : "hasRelatedSynonym", "val" : "serotonin release involved in inflammatory response", "xrefs" : [ "GOC:tb" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002443", "lbl" : "leukocyte mediated immunity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process involved in the carrying out of an immune response by a leukocyte.", "xrefs" : [ "GOC:add", "GO_REF:0000022", "ISBN:0781735149" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "immune cell effector process" }, { "pred" : "hasExactSynonym", "val" : "immune cell mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "leucocyte immune effector process" }, { "pred" : "hasExactSynonym", "val" : "leucocyte mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "leukocyte immune effector process" }, { "pred" : "hasRelatedSynonym", "val" : "cell-mediated immune response" }, { "pred" : "hasRelatedSynonym", "val" : "cellular immune response" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0019723" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0042087" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002444", "lbl" : "myeloid leukocyte mediated immunity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process involved in the carrying out of an immune response by a myeloid leukocyte.", "xrefs" : [ "GOC:add", "GO_REF:0000022", "ISBN:0781735149" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "myeloid leucocyte immune effector process" }, { "pred" : "hasExactSynonym", "val" : "myeloid leucocyte mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "myeloid leukocyte immune effector process" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002449", "lbl" : "lymphocyte mediated immunity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process involved in the carrying out of an immune response by a lymphocyte.", "xrefs" : [ "GOC:add", "GO_REF:0000022", "ISBN:0781735149" ] }, "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cell-mediated immunity" }, { "pred" : "hasBroadSynonym", "val" : "cellular immune response" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002520", "lbl" : "immune system development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.", "xrefs" : [ "GOC:add", "GOC:dph" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002521", "lbl" : "leukocyte differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.", "xrefs" : [ "CL:0000738", "GOC:add", "PMID:16551264" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "immune cell differentiation" }, { "pred" : "hasExactSynonym", "val" : "leucocyte differentiation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002523", "lbl" : "leukocyte migration involved in inflammatory response", "type" : "CLASS", "meta" : { "definition" : { "val" : "The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response.", "xrefs" : [ "GOC:add", "ISBN:0781735149", "PMID:14680625", "PMID:14708592", "PMID:7507411", "PMID:8600538" ] }, "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "immune cell migration during inflammatory response" }, { "pred" : "hasRelatedSynonym", "val" : "immune cell trafficking during inflammatory response" }, { "pred" : "hasRelatedSynonym", "val" : "leucocyte migration during inflammatory response" }, { "pred" : "hasRelatedSynonym", "val" : "leucocyte trafficking during inflammatory response" }, { "pred" : "hasRelatedSynonym", "val" : "leukocyte migration during inflammatory response", "xrefs" : [ "GOC:dph" ] }, { "pred" : "hasRelatedSynonym", "val" : "leukocyte trafficking during inflammatory response" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002532", "lbl" : "production of molecular mediator involved in inflammatory response", "type" : "CLASS", "meta" : { "definition" : { "val" : "The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels.", "xrefs" : [ "GOC:add", "GOC:dph", "GOC:tb", "ISBN:0781735149" ] }, "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "production of molecular mediator involved in acute inflammatory response" }, { "pred" : "hasRelatedSynonym", "val" : "production of cellular mediator of acute inflammation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002573", "lbl" : "myeloid leukocyte differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage.", "xrefs" : [ "GOC:add", "PMID:16551251" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "myeloid leucocyte differentiation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002682", "lbl" : "regulation of immune system process", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate, or extent of an immune system process.", "xrefs" : [ "GOC:add" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002683", "lbl" : "negative regulation of immune system process", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of immune system process" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of immune system process" }, { "pred" : "hasExactSynonym", "val" : "downregulation of immune system process" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of immune system process" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002684", "lbl" : "positive regulation of immune system process", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate, or extent of an immune system process.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "up regulation of immune system process" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of immune system process" }, { "pred" : "hasExactSynonym", "val" : "upregulation of immune system process" }, { "pred" : "hasNarrowSynonym", "val" : "activation of immune system process" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of immune system process" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002685", "lbl" : "regulation of leukocyte migration", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate, or extent of leukocyte migration.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "regulation of immune cell migration" }, { "pred" : "hasExactSynonym", "val" : "regulation of leucocyte migration" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002686", "lbl" : "negative regulation of leukocyte migration", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of leukocyte migration" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of leukocyte migration" }, { "pred" : "hasExactSynonym", "val" : "downregulation of leukocyte migration" }, { "pred" : "hasExactSynonym", "val" : "negative regulation of immune cell migration" }, { "pred" : "hasExactSynonym", "val" : "negative regulation of leucocyte migration" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of leukocyte migration" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002687", "lbl" : "positive regulation of leukocyte migration", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate, or extent of leukocyte migration.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "positive regulation of immune cell migration" }, { "pred" : "hasExactSynonym", "val" : "positive regulation of leucocyte migration" }, { "pred" : "hasExactSynonym", "val" : "up regulation of leukocyte migration" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of leukocyte migration" }, { "pred" : "hasExactSynonym", "val" : "upregulation of leukocyte migration" }, { "pred" : "hasNarrowSynonym", "val" : "activation of leukocyte migration" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of leukocyte migration" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002694", "lbl" : "regulation of leukocyte activation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate, or extent of leukocyte activation.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "regulation of immune cell activation" }, { "pred" : "hasExactSynonym", "val" : "regulation of leucocyte activation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002695", "lbl" : "negative regulation of leukocyte activation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of leukocyte activation" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of leukocyte activation" }, { "pred" : "hasExactSynonym", "val" : "downregulation of leukocyte activation" }, { "pred" : "hasExactSynonym", "val" : "negative regulation of immune cell activation" }, { "pred" : "hasExactSynonym", "val" : "negative regulation of leucocyte activation" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of leukocyte activation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002696", "lbl" : "positive regulation of leukocyte activation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate, or extent of leukocyte activation.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "positive regulation of immune cell activation" }, { "pred" : "hasExactSynonym", "val" : "positive regulation of leucocyte activation" }, { "pred" : "hasExactSynonym", "val" : "up regulation of leukocyte activation" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of leukocyte activation" }, { "pred" : "hasExactSynonym", "val" : "upregulation of leukocyte activation" }, { "pred" : "hasNarrowSynonym", "val" : "activation of leukocyte activation" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of leukocyte activation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002697", "lbl" : "regulation of immune effector process", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate, or extent of an immune effector process.", "xrefs" : [ "GOC:add" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002698", "lbl" : "negative regulation of immune effector process", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of immune effector process" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of immune effector process" }, { "pred" : "hasExactSynonym", "val" : "downregulation of immune effector process" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of immune effector process" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002699", "lbl" : "positive regulation of immune effector process", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate, or extent of an immune effector process.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "up regulation of immune effector process" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of immune effector process" }, { "pred" : "hasExactSynonym", "val" : "upregulation of immune effector process" }, { "pred" : "hasNarrowSynonym", "val" : "activation of immune effector process" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of immune effector process" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002703", "lbl" : "regulation of leukocyte mediated immunity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "regulation of immune cell mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "regulation of leucocyte mediated immunity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002704", "lbl" : "negative regulation of leukocyte mediated immunity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of leukocyte mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of leukocyte mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "downregulation of leukocyte mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "negative regulation of immune cell mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "negative regulation of leucocyte mediated immunity" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of leukocyte mediated immunity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002705", "lbl" : "positive regulation of leukocyte mediated immunity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "positive regulation of immune cell mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "positive regulation of leucocyte mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "up regulation of leukocyte mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of leukocyte mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "upregulation of leukocyte mediated immunity" }, { "pred" : "hasNarrowSynonym", "val" : "activation of leukocyte mediated immunity" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of leukocyte mediated immunity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002706", "lbl" : "regulation of lymphocyte mediated immunity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity.", "xrefs" : [ "GOC:add" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002707", "lbl" : "negative regulation of lymphocyte mediated immunity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of lymphocyte mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of lymphocyte mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "downregulation of lymphocyte mediated immunity" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of lymphocyte mediated immunity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002708", "lbl" : "positive regulation of lymphocyte mediated immunity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "up regulation of lymphocyte mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of lymphocyte mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "upregulation of lymphocyte mediated immunity" }, { "pred" : "hasNarrowSynonym", "val" : "activation of lymphocyte mediated immunity" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of lymphocyte mediated immunity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002761", "lbl" : "regulation of myeloid leukocyte differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation.", "xrefs" : [ "GOC:add" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002762", "lbl" : "negative regulation of myeloid leukocyte differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of myeloid leukocyte differentiation" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of myeloid leukocyte differentiation" }, { "pred" : "hasExactSynonym", "val" : "downregulation of myeloid leukocyte differentiation" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of myeloid leukocyte differentiation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002763", "lbl" : "positive regulation of myeloid leukocyte differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "up regulation of myeloid leukocyte differentiation" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of myeloid leukocyte differentiation" }, { "pred" : "hasExactSynonym", "val" : "upregulation of myeloid leukocyte differentiation" }, { "pred" : "hasNarrowSynonym", "val" : "activation of myeloid leukocyte differentiation" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of myeloid leukocyte differentiation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002790", "lbl" : "peptide secretion", "type" : "CLASS", "meta" : { "definition" : { "val" : "The controlled release of a peptide from a cell or a tissue.", "xrefs" : [ "GOC:add" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002791", "lbl" : "regulation of peptide secretion", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate, or extent of peptide secretion.", "xrefs" : [ "GOC:add" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002792", "lbl" : "negative regulation of peptide secretion", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of peptide secretion" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of peptide secretion" }, { "pred" : "hasExactSynonym", "val" : "downregulation of peptide secretion" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of peptide secretion" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002793", "lbl" : "positive regulation of peptide secretion", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate, or extent of peptide secretion.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "up regulation of peptide secretion" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of peptide secretion" }, { "pred" : "hasExactSynonym", "val" : "upregulation of peptide secretion" }, { "pred" : "hasNarrowSynonym", "val" : "activation of peptide secretion" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of peptide secretion" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002831", "lbl" : "regulation of response to biotic stimulus", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.", "xrefs" : [ "GOC:add" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002832", "lbl" : "negative regulation of response to biotic stimulus", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus.", "xrefs" : [ "GOC:add" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of response to biotic stimulus" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of response to biotic stimulus" }, { "pred" : "hasExactSynonym", "val" : "downregulation of response to biotic stimulus" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of response to biotic stimulus" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002833", "lbl" : "positive regulation of response to biotic stimulus", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus.", "xrefs" : [ "GOC:add" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "up regulation of response to biotic stimulus" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of response to biotic stimulus" }, { "pred" : "hasExactSynonym", "val" : "upregulation of response to biotic stimulus" }, { "pred" : "hasNarrowSynonym", "val" : "activation of response to biotic stimulus" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of response to biotic stimulus" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002886", "lbl" : "regulation of myeloid leukocyte mediated immunity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity.", "xrefs" : [ "GOC:add" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002887", "lbl" : "negative regulation of myeloid leukocyte mediated immunity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of myeloid leukocyte mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of myeloid leukocyte mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "downregulation of myeloid leukocyte mediated immunity" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of myeloid leukocyte mediated immunity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002888", "lbl" : "positive regulation of myeloid leukocyte mediated immunity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity.", "xrefs" : [ "GOC:add" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "up regulation of myeloid leukocyte mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of myeloid leukocyte mediated immunity" }, { "pred" : "hasExactSynonym", "val" : "upregulation of myeloid leukocyte mediated immunity" }, { "pred" : "hasNarrowSynonym", "val" : "activation of myeloid leukocyte mediated immunity" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of myeloid leukocyte mediated immunity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002932", "lbl" : "tendon sheath development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move.", "xrefs" : [ "PMID:20696843" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "hjd" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2012-04-23T02:11:22Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003002", "lbl" : "regionalization", "type" : "CLASS", "meta" : { "definition" : { "val" : "The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.", "xrefs" : [ "GOC:dph", "GOC:isa_complete" ] }, "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "pattern formation", "xrefs" : [ "GOC:dph" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003006", "lbl" : "developmental process involved in reproduction", "type" : "CLASS", "meta" : { "definition" : { "val" : "A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring.", "xrefs" : [ "GOC:dph", "GOC:isa_complete" ] }, "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "puberty", "xrefs" : [ "GOC:dph" ] }, { "pred" : "hasRelatedSynonym", "val" : "reproductive developmental process", "xrefs" : [ "GOC:dph", "GOC:tb" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003007", "lbl" : "heart morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.", "xrefs" : [ "GOC:dph", "GOC:isa_complete" ] }, "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "cardiac morphogenesis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003008", "lbl" : "system process", "type" : "CLASS", "meta" : { "definition" : { "val" : "A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.", "xrefs" : [ "GOC:mtg_cardio" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "organ system process" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003009", "lbl" : "skeletal muscle contraction", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control.", "xrefs" : [ "GOC:mtg_cardio", "GOC:mtg_muscle" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003012", "lbl" : "muscle system process", "type" : "CLASS", "meta" : { "definition" : { "val" : "A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers.", "xrefs" : [ "GOC:mtg_cardio" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "muscle physiological process" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003013", "lbl" : "circulatory system process", "type" : "CLASS", "meta" : { "definition" : { "val" : "A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism.", "xrefs" : [ "GOC:mtg_cardio" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic" ], "xrefs" : [ { "val" : "Wikipedia:Circulatory_system" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003015", "lbl" : "heart process", "type" : "CLASS", "meta" : { "definition" : { "val" : "A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.", "xrefs" : [ "GOC:mtg_cardio" ] }, "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "cardiac process" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003016", "lbl" : "respiratory system process", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange.", "xrefs" : [ "GOC:dph", "GOC:mtg_cardio", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_generic" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "respiratory gaseous exchange" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0010802" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003032", "lbl" : "detection of oxygen", "type" : "CLASS", "meta" : { "definition" : { "val" : "The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal.", "xrefs" : [ "GOC:mtg_cardio" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003131", "lbl" : "mesodermal-endodermal cell signaling", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that mediates the transfer of information from mesodermal cells to endodermal cells.", "xrefs" : [ "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesodermal-endodermal cell signalling", "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-09-22T03:07:34Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003133", "lbl" : "endodermal-mesodermal cell signaling", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that mediates the transfer of information from endodermal cells to mesodermal cells.", "xrefs" : [ "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "endodermal-mesodermal cell signalling", "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-09-22T03:10:29Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003142", "lbl" : "cardiogenic plate morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field.", "xrefs" : [ "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cardiac crescent morphogenesis", "xrefs" : [ "GOC:mtg_heart" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-09-22T04:12:18Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003143", "lbl" : "embryonic heart tube morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-09-22T04:21:17Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003144", "lbl" : "embryonic heart tube formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-09-22T04:22:34Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003145", "lbl" : "embryonic heart tube formation via epithelial folding", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-09-22T04:26:03Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003147", "lbl" : "neural crest cell migration involved in heart formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-09-22T04:29:55Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003148", "lbl" : "outflow tract septum morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-09-22T07:51:01Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003149", "lbl" : "membranous septum morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-09-22T07:51:41Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003150", "lbl" : "muscular septum morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-09-22T07:53:28Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003151", "lbl" : "outflow tract morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.", "xrefs" : [ "GOC:mtg_heart", "UBERON:0004145" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-09-22T07:59:24Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003152", "lbl" : "morphogenesis of an epithelial fold involved in embryonic heart tube formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-09-23T10:10:24Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003156", "lbl" : "regulation of animal organ formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment.", "xrefs" : [ "GOC:dph", "GOC:mtg_heart", "GOC:tb" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-09-30T11:21:09Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003157", "lbl" : "endocardium development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-01T12:42:27Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003158", "lbl" : "endothelium development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-01T12:50:57Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003159", "lbl" : "morphogenesis of an endothelium", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-01T01:34:06Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003160", "lbl" : "endocardium morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-01T01:37:26Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003161", "lbl" : "cardiac conduction system development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat.", "xrefs" : [ "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cardiac impulse conducting system development", "xrefs" : [ "GOC:mtg_heart" ] }, { "pred" : "hasExactSynonym", "val" : "heart conduction system development", "xrefs" : [ "GOC:mtg_heart" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-01T01:57:16Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003162", "lbl" : "atrioventricular node development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system.", "xrefs" : [ "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "AV node development", "xrefs" : [ "GOC:mtg_heart" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-01T02:05:13Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003163", "lbl" : "sinoatrial node development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node.", "xrefs" : [ "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "SA node development", "xrefs" : [ "GOC:mtg_heart" ] }, { "pred" : "hasExactSynonym", "val" : "SAN development", "xrefs" : [ "GOC:BHF", "GOC:mtg_cardiac_conduct_nov11" ] }, { "pred" : "hasNarrowSynonym", "val" : "sinus node development", "xrefs" : [ "GOC:BHF", "GOC:mtg_cardiac_conduct_nov11" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-01T02:06:09Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003164", "lbl" : "His-Purkinje system development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-01T02:07:12Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003165", "lbl" : "Purkinje myocyte development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle.", "xrefs" : [ "GOC:mtg_cardiac_conduct_nov11", "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cardiac Purkinje fiber development" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-01T02:07:50Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003168", "lbl" : "Purkinje myocyte differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle.", "xrefs" : [ "GOC:mtg_cardiac_conduct_nov11", "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cardiac Purkinje fiber cell differentiation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-01T02:49:54Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003169", "lbl" : "coronary vein morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the anatomical structures of veins of the heart are generated and organized.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-08T10:45:41Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003197", "lbl" : "endocardial cushion development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-08T01:17:43Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003203", "lbl" : "endocardial cushion morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-08T01:43:22Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003204", "lbl" : "cardiac skeleton development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart.", "xrefs" : [ "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "heart fibrous skeleton development", "xrefs" : [ "GOC:mtg_heart" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T09:05:04Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003205", "lbl" : "cardiac chamber development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T09:11:18Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003206", "lbl" : "cardiac chamber morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart.", "xrefs" : [ "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "heart chamber morphogenesis", "xrefs" : [ "GOC:mtg_heart" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T09:14:51Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003207", "lbl" : "cardiac chamber formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart.", "xrefs" : [ "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "heart chamber formation", "xrefs" : [ "GOC:mtg_heart" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T09:29:13Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003208", "lbl" : "cardiac ventricle morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T09:38:44Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003209", "lbl" : "cardiac atrium morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T09:39:44Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003210", "lbl" : "cardiac atrium formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T09:44:25Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003211", "lbl" : "cardiac ventricle formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T09:46:27Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003212", "lbl" : "cardiac left atrium morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the left cardiac atrium is generated and organized.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T09:48:16Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003213", "lbl" : "cardiac right atrium morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the right cardiac atrium is generated and organized.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T09:49:03Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003214", "lbl" : "cardiac left ventricle morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the left cardiac ventricle is generated and organized.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T09:50:08Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003215", "lbl" : "cardiac right ventricle morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the right cardiac ventricle is generated and organized.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T09:50:57Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003216", "lbl" : "cardiac left atrium formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T09:52:31Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003217", "lbl" : "cardiac right atrium formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T09:53:12Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003218", "lbl" : "cardiac left ventricle formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T09:54:33Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003219", "lbl" : "cardiac right ventricle formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T09:55:38Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003220", "lbl" : "left ventricular cardiac muscle tissue morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized.", "xrefs" : [ "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "left ventricular myocardium morphogenesis", "xrefs" : [ "GOC:mtg_heart" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T10:18:05Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003221", "lbl" : "right ventricular cardiac muscle tissue morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized.", "xrefs" : [ "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "right ventricle myocardium morphogenesis", "xrefs" : [ "GOC:mtg_heart" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T10:26:33Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003228", "lbl" : "atrial cardiac muscle tissue development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure.", "xrefs" : [ "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "atrial myocardium development", "xrefs" : [ "GOC:mtg_heart" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T10:53:18Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003229", "lbl" : "ventricular cardiac muscle tissue development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure.", "xrefs" : [ "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "ventricular myocardium development", "xrefs" : [ "GOC:mtg_heart" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T10:56:01Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003230", "lbl" : "cardiac atrium development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T11:02:07Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003231", "lbl" : "cardiac ventricle development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T11:03:16Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003235", "lbl" : "sinus venosus development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T11:12:34Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003236", "lbl" : "sinus venosus morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T11:16:52Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003237", "lbl" : "sinus venosus formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T11:18:34Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003241", "lbl" : "growth involved in heart morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "Developmental growth that contributes to the shaping of the heart.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T11:28:46Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003245", "lbl" : "cardiac muscle tissue growth involved in heart morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T11:44:21Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003248", "lbl" : "heart capillary growth", "type" : "CLASS", "meta" : { "definition" : { "val" : "The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T11:53:12Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003253", "lbl" : "cardiac neural crest cell migration involved in outflow tract morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-13T02:14:16Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003260", "lbl" : "cardioblast migration", "type" : "CLASS", "meta" : { "definition" : { "val" : "The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-15T01:52:25Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003272", "lbl" : "endocardial cushion formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.", "xrefs" : [ "GOC:mtg_heart", "PMID:15797462" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-20T08:53:19Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003273", "lbl" : "cell migration involved in endocardial cushion formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-20T09:08:44Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003275", "lbl" : "apoptotic process involved in outflow tract morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries.", "xrefs" : [ "GOC:mtg_apoptosis", "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "apoptosis involved in outflow tract morphogenesis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-20T09:30:01Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003277", "lbl" : "apoptotic process involved in endocardial cushion morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.", "xrefs" : [ "GOC:mtg_apoptosis", "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "apoptosis involved in endocardial cushion morphogenesis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-20T09:37:03Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003278", "lbl" : "apoptotic process involved in heart morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any apoptotic process that contributes to the shaping of the heart.", "xrefs" : [ "GOC:mtg_apoptosis", "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "apoptosis involved in heart morphogenesis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-20T09:40:22Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003279", "lbl" : "cardiac septum development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The progression of a cardiac septum over time, from its initial formation to the mature structure.", "xrefs" : [ "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "heart septum development", "xrefs" : [ "GOC:mtg_heart" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-20T09:45:13Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003281", "lbl" : "ventricular septum development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The progression of the ventricular septum over time from its formation to the mature structure.", "xrefs" : [ "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "interventricular septum development", "xrefs" : [ "GOC:mtg_heart" ] }, { "pred" : "hasNarrowSynonym", "val" : "septum inferius development", "xrefs" : [ "GOC:mtg_heart" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-20T10:04:51Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003283", "lbl" : "atrial septum development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The progression of the atrial septum over time, from its initial formation to the mature structure.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-20T10:10:38Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003292", "lbl" : "cardiac septum cell differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which an endocardial cushion cell becomes a cell of a cardiac septum.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-20T11:03:46Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003298", "lbl" : "physiological muscle hypertrophy", "type" : "CLASS", "meta" : { "definition" : { "val" : "The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-22T09:24:51Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003300", "lbl" : "cardiac muscle hypertrophy", "type" : "CLASS", "meta" : { "definition" : { "val" : "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division.", "xrefs" : [ "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-22T10:33:56Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003301", "lbl" : "physiological cardiac muscle hypertrophy", "type" : "CLASS", "meta" : { "definition" : { "val" : "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart.", "xrefs" : [ "GOC:BHF", "GOC:mtg_cardiac_conduct_nov11", "GOC:mtg_heart" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-22T10:38:10Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003313", "lbl" : "heart rudiment development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube.", "xrefs" : [ "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "heart cone development", "xrefs" : [ "GOC:mtg_heart" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-27T08:32:40Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003314", "lbl" : "heart rudiment morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the anatomical structures of the heart rudiment are generated and organized.", "xrefs" : [ "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "heart cone morphogenesis", "xrefs" : [ "GOC:mtg_heart" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-27T08:38:04Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003315", "lbl" : "heart rudiment formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The developmental process pertaining to the initial formation of the heart rudiment.", "xrefs" : [ "GOC:mtg_heart" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "heart cone formation", "xrefs" : [ "GOC:mtg_heart" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-10-27T08:43:37Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003333", "lbl" : "amino acid transmembrane transport", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which an amino acid is transported across a membrane.", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, "comments" : [ "Note that this term is not intended for use in annotating lateral movement within membranes." ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "amino acid membrane transport" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-11-02T02:36:11Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003341", "lbl" : "cilium movement", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed, self-propelled movement of a cilium.", "xrefs" : [ "GOC:dph", "GOC:jl" ] }, "comments" : [ "Note that we deem cilium and microtubule-based flagellum to be equivalent." ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "microtubule-based flagellum movement" }, { "pred" : "hasNarrowSynonym", "val" : "flagellar movement", "xrefs" : [ "GOC:bf" ] }, { "pred" : "hasNarrowSynonym", "val" : "flagellum movement" }, { "pred" : "hasRelatedSynonym", "val" : "ciliary motility" }, { "pred" : "hasRelatedSynonym", "val" : "cilium beating", "xrefs" : [ "GOC:ascb_2009", "GOC:dph", "GOC:tb" ] }, { "pred" : "hasRelatedSynonym", "val" : "flagellar motility" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-11-24T09:56:26Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0036142" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003342", "lbl" : "proepicardium development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum.", "xrefs" : [ "GOC:dph", "PMID:18722343" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-01T10:30:17Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003343", "lbl" : "septum transversum development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme.", "xrefs" : [ "GOC:dph", "PMID:18722343" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-01T10:40:17Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003344", "lbl" : "pericardium morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the anatomical structure of the pericardium is generated and organized.", "xrefs" : [ "GOC:dph", "PMID:18722343" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-01T10:46:34Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003348", "lbl" : "cardiac endothelial cell differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell.", "xrefs" : [ "GOC:dph", "PMID:18722343" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-01T11:12:05Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003352", "lbl" : "regulation of cilium movement", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.", "xrefs" : [ "GOC:dph" ] }, "comments" : [ "Note that we deem cilium and microtubule-based flagellum to be equivalent." ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "regulation of microtubule-based flagellum movement" }, { "pred" : "hasRelatedSynonym", "val" : "regulation of flagellar movement", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "regulation of flagellum movement" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-03T10:12:00Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:1900172" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003353", "lbl" : "positive regulation of cilium movement", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.", "xrefs" : [ "GOC:dph" ] }, "comments" : [ "Note that we deem cilium and microtubule-based flagellum to be equivalent." ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "positive regulation of microtubule-based flagellum movement" }, { "pred" : "hasRelatedSynonym", "val" : "positive regulation of flagellar movement", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "positive regulation of flagellum movement" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-03T10:16:10Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:1900174" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003354", "lbl" : "negative regulation of cilium movement", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.", "xrefs" : [ "GOC:dph" ] }, "comments" : [ "Note that we deem cilium and microtubule-based flagellum to be equivalent." ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "negative regulation of microtubule-based flagellum movement" }, { "pred" : "hasRelatedSynonym", "val" : "negative regulation of flagellum movement" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-03T10:17:47Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:1900173" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003357", "lbl" : "noradrenergic neuron differentiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline.", "xrefs" : [ "GOC:dph" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "norepinephrine secreting neuron differentiation", "xrefs" : [ "GOC:dph" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-03T10:34:30Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003358", "lbl" : "noradrenergic neuron development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.", "xrefs" : [ "GOC:dph" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "norepinephrine secreting neuron development", "xrefs" : [ "GOC:dph" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-03T10:38:37Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003360", "lbl" : "brainstem development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord.", "xrefs" : [ "GOC:dph" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-03T10:47:20Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003361", "lbl" : "noradrenergic neuron differentiation involved in brainstem development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem.", "xrefs" : [ "GOC:dph" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-03T10:53:30Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003365", "lbl" : "establishment of cell polarity involved in ameboidal cell migration", "type" : "CLASS", "meta" : { "definition" : { "val" : "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell.", "xrefs" : [ "GOC:ascb_2009", "GOC:dph", "GOC:tb" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-08T04:50:41Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003371", "lbl" : "establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell.", "xrefs" : [ "GOC:ascb_2009", "GOC:dph", "GOC:tb" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-08T05:42:46Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003379", "lbl" : "establishment of cell polarity involved in gastrulation cell migration", "type" : "CLASS", "meta" : { "definition" : { "val" : "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation.", "xrefs" : [ "GOC:ascb_2009", "GOC:dph", "GOC:tb" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-09T06:54:44Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003380", "lbl" : "establishment or maintenance of cytoskeleton polarity involved in gastrulation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation.", "xrefs" : [ "GOC:ascb_2009", "GOC:dph", "GOC:tb" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-09T07:10:57Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003381", "lbl" : "epithelial cell morphogenesis involved in gastrulation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation.", "xrefs" : [ "GOC:ascb_2009", "GOC:dph", "GOC:tb" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-09T07:18:53Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003382", "lbl" : "epithelial cell morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state.", "xrefs" : [ "GOC:ascb_2009", "GOC:dph", "GOC:tb" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-09T07:21:06Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003403", "lbl" : "optic vesicle formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.", "xrefs" : [ "GOC:ascb_2009", "GOC:dph", "GOC:tb" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-21T01:42:37Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003404", "lbl" : "optic vesicle morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.", "xrefs" : [ "GOC:ascb_2009", "GOC:dph", "GOC:tb" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-21T01:54:34Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003407", "lbl" : "neural retina development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.", "xrefs" : [ "GOC:ascb_2009", "GOC:dph", "GOC:tb" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-21T02:15:14Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003411", "lbl" : "cell motility involved in camera-type eye morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye.", "xrefs" : [ "GOC:ascb_2009", "GOC:dph", "GOC:tb" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-21T03:04:27Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003413", "lbl" : "chondrocyte differentiation involved in endochondral bone morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage.", "xrefs" : [ "GOC:ascb_2009", "GOC:dph", "GOC:tb" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-22T08:39:58Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003414", "lbl" : "chondrocyte morphogenesis involved in endochondral bone morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized.", "xrefs" : [ "GOC:ascb_2009", "GOC:dph", "GOC:tb" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-22T08:42:55Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003416", "lbl" : "endochondral bone growth", "type" : "CLASS", "meta" : { "definition" : { "val" : "The increase in size or mass of an endochondral bone that contributes to the shaping of the bone.", "xrefs" : [ "GOC:ascb_2009", "GOC:dph", "GOC:tb" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-22T08:52:55Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003433", "lbl" : "chondrocyte development involved in endochondral bone morphogenesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone.", "xrefs" : [ "GOC:ascb_2009", "GOC:dph", "GOC:tb" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-12-22T12:42:44Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005575", "lbl" : "cellular_component", "type" : "CLASS", "meta" : { "definition" : { "val" : "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).", "xrefs" : [ "GOC:pdt" ] }, "comments" : [ "Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell or subcellular entity" }, { "pred" : "hasExactSynonym", "val" : "cellular component" }, { "pred" : "hasRelatedSynonym", "val" : "subcellular entity", "xrefs" : [ "NIF_Subcellular:nlx_subcell_100315" ] } ], "xrefs" : [ { "val" : "NIF_Subcellular:sao1337158144" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0008372" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005576", "lbl" : "extracellular region", "type" : "CLASS", "meta" : { "definition" : { "val" : "The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.", "xrefs" : [ "GOC:go_curators" ] }, "comments" : [ "Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_plant_ribbon", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "extracellular" } ], "xrefs" : [ { "val" : "Wikipedia:Extracellular" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005577", "lbl" : "fibrinogen complex", "type" : "CLASS", "meta" : { "definition" : { "val" : "A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.", "xrefs" : [ "ISBN:0198547684" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "fibrinogen" }, { "pred" : "hasNarrowSynonym", "val" : "fibrinogen alpha chain" }, { "pred" : "hasNarrowSynonym", "val" : "fibrinogen beta chain" }, { "pred" : "hasNarrowSynonym", "val" : "fibrinogen gamma chain" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005581", "lbl" : "collagen trimer", "type" : "CLASS", "meta" : { "definition" : { "val" : "A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures.", "xrefs" : [ "GOC:dos", "GOC:mah", "ISBN:0721639976", "PMID:19693541", "PMID:21421911" ] }, "xrefs" : [ { "val" : "Wikipedia:Collagen" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005583", "lbl" : "fibrillar collagen trimer", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any triple helical collagen trimer that forms fibrils.", "xrefs" : [ "GOC:mah", "ISBN:0721639976", "PMID:21421911" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005587", "lbl" : "collagen type IV trimer", "type" : "CLASS", "meta" : { "definition" : { "val" : "A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes.", "xrefs" : [ "ISBN:0721639976", "PMID:19693541", "PMID:21421911" ] }, "xrefs" : [ { "val" : "Wikipedia:Collagen_type_IV" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005604", "lbl" : "basement membrane", "type" : "CLASS", "meta" : { "definition" : { "val" : "A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.", "xrefs" : [ "ISBN:0198547684", "PMID:22505934" ] }, "comments" : [ "Note that this term has no relationship to 'membrane ; GO:0016020' because the basement membrane is not a lipid bilayer." ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "basal lamina" }, { "pred" : "hasRelatedSynonym", "val" : "basement lamina" }, { "pred" : "hasRelatedSynonym", "val" : "lamina densa" } ], "xrefs" : [ { "val" : "Wikipedia:Basement_membrane" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0005605" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0008003" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005615", "lbl" : "extracellular space", "type" : "CLASS", "meta" : { "definition" : { "val" : "That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.", "xrefs" : [ "ISBN:0198547684" ] }, "comments" : [ "Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "intercellular space" } ], "xrefs" : [ { "val" : "NIF_Subcellular:sao1425028079" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005622", "lbl" : "intracellular anatomical structure", "type" : "CLASS", "meta" : { "definition" : { "val" : "A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm.", "xrefs" : [ "ISBN:0198506732" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "internal to cell" }, { "pred" : "hasExactSynonym", "val" : "intracellular" }, { "pred" : "hasExactSynonym", "val" : "protoplasm" }, { "pred" : "hasRelatedSynonym", "val" : "nucleocytoplasm", "xrefs" : [ "GOC:mah" ] }, { "pred" : "hasRelatedSynonym", "val" : "protoplast", "xrefs" : [ "GOC:mah" ] } ], "xrefs" : [ { "val" : "Wikipedia:Intracellular" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005634", "lbl" : "nucleus", "type" : "CLASS", "meta" : { "definition" : { "val" : "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.", "xrefs" : [ "GOC:go_curators" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_plant_ribbon", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell nucleus" }, { "pred" : "hasNarrowSynonym", "val" : "horsetail nucleus", "xrefs" : [ "GOC:al", "GOC:mah", "GOC:vw", "PMID:15030757" ] } ], "xrefs" : [ { "val" : "NIF_Subcellular:sao1702920020" }, { "val" : "Wikipedia:Cell_nucleus" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005635", "lbl" : "nuclear envelope", "type" : "CLASS", "meta" : { "definition" : { "val" : "The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).", "xrefs" : [ "ISBN:0198547684" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "xrefs" : [ { "val" : "Wikipedia:Nuclear_envelope" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0005636" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005640", "lbl" : "nuclear outer membrane", "type" : "CLASS", "meta" : { "definition" : { "val" : "The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes.", "xrefs" : [ "ISBN:0198547684" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "nucleus outer envelope" }, { "pred" : "hasExactSynonym", "val" : "perinuclear membrane" } ], "xrefs" : [ { "val" : "NIF_Subcellular:sao1617136075" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005694", "lbl" : "chromosome", "type" : "CLASS", "meta" : { "definition" : { "val" : "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.", "xrefs" : [ "ISBN:0198547684" ] }, "comments" : [ "Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "interphase chromosome" }, { "pred" : "hasNarrowSynonym", "val" : "prophase chromosome" }, { "pred" : "hasRelatedSynonym", "val" : "chromatid" } ], "xrefs" : [ { "val" : "Wikipedia:Chromosome" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005730", "lbl" : "nucleolus", "type" : "CLASS", "meta" : { "definition" : { "val" : "A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.", "xrefs" : [ "ISBN:0198506732" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "xrefs" : [ { "val" : "NIF_Subcellular:sao1820400233" }, { "val" : "Wikipedia:Nucleolus" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005737", "lbl" : "cytoplasm", "type" : "CLASS", "meta" : { "definition" : { "val" : "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.", "xrefs" : [ "ISBN:0198547684" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_plant_ribbon", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "xrefs" : [ { "val" : "Wikipedia:Cytoplasm" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005773", "lbl" : "vacuole", "type" : "CLASS", "meta" : { "definition" : { "val" : "A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.", "xrefs" : [ "GOC:mtg_sensu", "ISBN:0198506732" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_plant_ribbon", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "vacuolar carboxypeptidase Y" } ], "xrefs" : [ { "val" : "Wikipedia:Vacuole" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005774", "lbl" : "vacuolar membrane", "type" : "CLASS", "meta" : { "definition" : { "val" : "The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.", "xrefs" : [ "GOC:ai" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005775", "lbl" : "vacuolar lumen", "type" : "CLASS", "meta" : { "definition" : { "val" : "The volume enclosed within the vacuolar membrane.", "xrefs" : [ "ISBN:0198506732" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005794", "lbl" : "Golgi apparatus", "type" : "CLASS", "meta" : { "definition" : { "val" : "A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.", "xrefs" : [ "ISBN:0198506732" ] }, "comments" : [ "Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_plant_ribbon", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "Golgi" }, { "pred" : "hasExactSynonym", "val" : "Golgi complex" }, { "pred" : "hasNarrowSynonym", "val" : "Golgi ribbon" } ], "xrefs" : [ { "val" : "NIF_Subcellular:sao451912436" }, { "val" : "Wikipedia:Golgi_apparatus" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005798", "lbl" : "Golgi-associated vesicle", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell.", "xrefs" : [ "GOC:mah" ] }, "comments" : [ "Note that this definition includes vesicles that are transiently associated with the Golgi." ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "Golgi vesicle" }, { "pred" : "hasRelatedSynonym", "val" : "vesicular component", "xrefs" : [ "NIF_Subcellular:sao138219748" ] } ], "xrefs" : [ { "val" : "NIF_Subcellular:sao819927218" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005829", "lbl" : "cytosol", "type" : "CLASS", "meta" : { "definition" : { "val" : "The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.", "xrefs" : [ "GOC:hjd", "GOC:jl" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "xrefs" : [ { "val" : "NIF_Subcellular:sao101633890" }, { "val" : "Wikipedia:Cytosol" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005840", "lbl" : "ribosome", "type" : "CLASS", "meta" : { "definition" : { "val" : "An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.", "xrefs" : [ "ISBN:0198506732" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_plant_ribbon", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "free ribosome", "xrefs" : [ "NIF_Subcellular:sao1139385046" ] }, { "pred" : "hasNarrowSynonym", "val" : "membrane bound ribosome", "xrefs" : [ "NIF_Subcellular:sao1291545653" ] }, { "pred" : "hasRelatedSynonym", "val" : "ribosomal RNA" } ], "xrefs" : [ { "val" : "NIF_Subcellular:sao1429207766" }, { "val" : "Wikipedia:Ribosome" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0033279" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005856", "lbl" : "cytoskeleton", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.", "xrefs" : [ "GOC:mah", "PMID:16959967", "PMID:27419875" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_plant_ribbon", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "xrefs" : [ { "val" : "Wikipedia:Cytoskeleton" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005874", "lbl" : "microtubule", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.", "xrefs" : [ "ISBN:0879693568" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_metagenomics" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "microtubuli" }, { "pred" : "hasExactSynonym", "val" : "microtubulus" }, { "pred" : "hasNarrowSynonym", "val" : "neurotubule", "xrefs" : [ "NIF_Subcellular:sao248349196" ] } ], "xrefs" : [ { "val" : "NIF_Subcellular:sao1846835077" }, { "val" : "Wikipedia:Microtubule" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005879", "lbl" : "axonemal microtubule", "type" : "CLASS", "meta" : { "definition" : { "val" : "A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules.", "xrefs" : [ "GOC:cilia", "ISBN:0815316194" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005880", "lbl" : "nuclear microtubule", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any microtubule in the nucleus of a cell.", "xrefs" : [ "GOC:mah" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005881", "lbl" : "cytoplasmic microtubule", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any microtubule in the cytoplasm of a cell.", "xrefs" : [ "GOC:mah" ] }, "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "non-spindle-associated astral microtubule" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005884", "lbl" : "actin filament", "type" : "CLASS", "meta" : { "definition" : { "val" : "A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.", "xrefs" : [ "GOC:mah", "ISBN:0198506732", "PMID:10666339" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "microfilament" } ], "xrefs" : [ { "val" : "FMA:63850" }, { "val" : "NIF_Subcellular:sao1588493326" }, { "val" : "Wikipedia:Actin" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005886", "lbl" : "plasma membrane", "type" : "CLASS", "meta" : { "definition" : { "val" : "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.", "xrefs" : [ "ISBN:0716731363" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_plant_ribbon", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "juxtamembrane" }, { "pred" : "hasExactSynonym", "val" : "cell membrane" }, { "pred" : "hasExactSynonym", "val" : "cellular membrane", "xrefs" : [ "NIF_Subcellular:sao6433132645" ] }, { "pred" : "hasExactSynonym", "val" : "cytoplasmic membrane" }, { "pred" : "hasExactSynonym", "val" : "plasmalemma" }, { "pred" : "hasNarrowSynonym", "val" : "bacterial inner membrane" }, { "pred" : "hasNarrowSynonym", "val" : "inner endospore membrane" }, { "pred" : "hasNarrowSynonym", "val" : "integral component of plasma membrane" }, { "pred" : "hasNarrowSynonym", "val" : "integral to plasma membrane" }, { "pred" : "hasNarrowSynonym", "val" : "plasma membrane lipid bilayer", "xrefs" : [ "GOC:mah" ] } ], "xrefs" : [ { "val" : "NIF_Subcellular:sao1663586795" }, { "val" : "Wikipedia:Cell_membrane" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0005887" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0005904" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005911", "lbl" : "cell-cell junction", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects.", "xrefs" : [ "GOC:aruk", "GOC:bc", "GOC:dgh", "GOC:hb", "GOC:mah", "PMID:21422226", "PMID:28096264" ] }, "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cell-cell contact region" }, { "pred" : "hasBroadSynonym", "val" : "cell-cell contact zone" }, { "pred" : "hasExactSynonym", "val" : "intercellular junction", "xrefs" : [ "NIF_Subcellular:sao1395777368" ] } ], "xrefs" : [ { "val" : "NIF_Subcellular:sao1922892319" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005929", "lbl" : "cilium", "type" : "CLASS", "meta" : { "definition" : { "val" : "A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.", "xrefs" : [ "GOC:cilia", "GOC:curators", "GOC:kmv", "GOC:vw", "ISBN:0198547684", "PMID:16824949", "PMID:17009929", "PMID:20144998" ] }, "comments" : [ "Note that we deem cilium and microtubule-based flagellum to be equivalent. In most eukaryotic species, intracellular sub-components of the cilium, such as the ciliary base and rootlet, are located near the plasma membrane. In Diplomonads such as Giardia, instead, the same ciliary parts are located further intracellularly. Also, 'cilium' may be used when axonemal structure and/or motility are unknown, or when axonemal structure is unusual. For all other cases, please refer to children of 'cilium'. Finally, note that any role of ciliary proteins in sensory events should be captured by annotating to relevant biological process terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "eukaryotic flagellum" }, { "pred" : "hasExactSynonym", "val" : "microtubule-based flagellum" }, { "pred" : "hasNarrowSynonym", "val" : "primary cilium" }, { "pred" : "hasRelatedSynonym", "val" : "flagellum" } ], "xrefs" : [ { "val" : "FMA:67181" }, { "val" : "NIF_Subcellular:sao787716553" }, { "val" : "Wikipedia:Cilium" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0072372" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005930", "lbl" : "axoneme", "type" : "CLASS", "meta" : { "definition" : { "val" : "The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.", "xrefs" : [ "GOC:bf", "GOC:cilia", "ISBN:0198547684" ] }, "comments" : [ "Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "ciliary axoneme" }, { "pred" : "hasExactSynonym", "val" : "cilium axoneme" }, { "pred" : "hasExactSynonym", "val" : "flagellar axoneme" }, { "pred" : "hasExactSynonym", "val" : "flagellum axoneme" } ], "xrefs" : [ { "val" : "Wikipedia:Axoneme" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0035085" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0035086" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005938", "lbl" : "cell cortex", "type" : "CLASS", "meta" : { "definition" : { "val" : "The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.", "xrefs" : [ "GOC:mah", "ISBN:0815316194" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "ectoplasm" }, { "pred" : "hasRelatedSynonym", "val" : "cell periphery" }, { "pred" : "hasRelatedSynonym", "val" : "peripheral cytoplasm" } ], "xrefs" : [ { "val" : "Wikipedia:Cell_cortex" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005975", "lbl" : "carbohydrate metabolic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.", "xrefs" : [ "GOC:mah", "ISBN:0198506732" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_plant_ribbon", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "carbohydrate metabolism" } ], "xrefs" : [ { "val" : "Wikipedia:Carbohydrate_metabolism" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "jl" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2012-10-23T15:40:34Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0044261" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0044723" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005976", "lbl" : "polysaccharide metabolic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.", "xrefs" : [ "ISBN:0198547684" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "polysaccharide metabolism" }, { "pred" : "hasNarrowSynonym", "val" : "glycan metabolic process" }, { "pred" : "hasNarrowSynonym", "val" : "glycan metabolism" }, { "pred" : "hasNarrowSynonym", "val" : "multicellular organismal polysaccharide metabolic process" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0044263" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006022", "lbl" : "aminoglycan metabolic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.", "xrefs" : [ "GOC:ai", "ISBN:0198506732" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "aminoglycan metabolism" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006023", "lbl" : "aminoglycan biosynthetic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.", "xrefs" : [ "GOC:ai", "ISBN:0198506732" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "aminoglycan anabolism" }, { "pred" : "hasExactSynonym", "val" : "aminoglycan biosynthesis" }, { "pred" : "hasExactSynonym", "val" : "aminoglycan formation" }, { "pred" : "hasExactSynonym", "val" : "aminoglycan synthesis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006024", "lbl" : "glycosaminoglycan biosynthetic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars.", "xrefs" : [ "ISBN:0192800981" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "glycosaminoglycan anabolism" }, { "pred" : "hasExactSynonym", "val" : "glycosaminoglycan biosynthesis" }, { "pred" : "hasExactSynonym", "val" : "glycosaminoglycan formation" }, { "pred" : "hasExactSynonym", "val" : "glycosaminoglycan synthesis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006082", "lbl" : "organic acid metabolic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.", "xrefs" : [ "ISBN:0198506732" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "organic acid metabolism" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006083", "lbl" : "acetate metabolic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "The chemical reactions and pathways involving acetate, the anion of acetic acid.", "xrefs" : [ "GOC:go_curators" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "acetate metabolism" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006109", "lbl" : "regulation of carbohydrate metabolic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.", "xrefs" : [ "GOC:go_curators" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "regulation of carbohydrate metabolism" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006139", "lbl" : "nucleobase-containing compound metabolic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" }, { "pred" : "hasExactSynonym", "val" : "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolism" }, { "pred" : "hasExactSynonym", "val" : "nucleobase, nucleoside, nucleotide and nucleic acid metabolism" }, { "pred" : "hasRelatedSynonym", "val" : "nucleobase, nucleoside and nucleotide metabolic process" }, { "pred" : "hasRelatedSynonym", "val" : "nucleobase, nucleoside, nucleotide and nucleic acid metabolic process", "xrefs" : [ "GOC:dph", "GOC:tb" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0055134" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006325", "lbl" : "chromatin organization", "type" : "CLASS", "meta" : { "definition" : { "val" : "The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA.", "xrefs" : [ "PMID:20404130" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "chromatin maintenance" }, { "pred" : "hasExactSynonym", "val" : "chromatin organisation", "xrefs" : [ "GOC:mah" ] }, { "pred" : "hasExactSynonym", "val" : "establishment of chromatin architecture", "xrefs" : [ "GOC:mah" ] }, { "pred" : "hasExactSynonym", "val" : "establishment or maintenance of chromatin architecture", "xrefs" : [ "GOC:mah" ] }, { "pred" : "hasNarrowSynonym", "val" : "DNA replication-independent chromatin assembly" }, { "pred" : "hasNarrowSynonym", "val" : "DNA replication-independent chromatin organization" }, { "pred" : "hasNarrowSynonym", "val" : "DNA replication-independent nucleosome organisation" }, { "pred" : "hasNarrowSynonym", "val" : "DNA replication-independent nuclesome assembly" }, { "pred" : "hasNarrowSynonym", "val" : "chromatin assembly" }, { "pred" : "hasNarrowSynonym", "val" : "transcription-coupled nucleosome assembly" }, { "pred" : "hasRelatedSynonym", "val" : "chromatin assembly or disassembly" }, { "pred" : "hasRelatedSynonym", "val" : "chromatin assembly/disassembly" }, { "pred" : "hasRelatedSynonym", "val" : "chromatin modification" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0006333" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0006336" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0016568" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0031497" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0034724" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006403", "lbl" : "RNA localization", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process in which RNA is transported to, or maintained in, a specific location.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "RNA localisation", "xrefs" : [ "GOC:mah" ] }, { "pred" : "hasExactSynonym", "val" : "establishment and maintenance of RNA localization" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006404", "lbl" : "RNA import into nucleus", "type" : "CLASS", "meta" : { "definition" : { "val" : "The import of RNA from the cytoplasm to the nucleus.", "xrefs" : [ "GOC:ma" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "RNA import into cell nucleus" }, { "pred" : "hasExactSynonym", "val" : "RNA transport from cytoplasm to nucleus" }, { "pred" : "hasExactSynonym", "val" : "RNA-nucleus import" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006405", "lbl" : "RNA export from nucleus", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed movement of RNA from the nucleus to the cytoplasm.", "xrefs" : [ "GOC:ma" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "RNA export from cell nucleus" }, { "pred" : "hasExactSynonym", "val" : "RNA export out of nucleus" }, { "pred" : "hasExactSynonym", "val" : "RNA transport from nucleus to cytoplasm" }, { "pred" : "hasExactSynonym", "val" : "RNA-nucleus export" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006412", "lbl" : "translation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.", "xrefs" : [ "GOC:go_curators" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein anabolism" }, { "pred" : "hasExactSynonym", "val" : "protein biosynthesis" }, { "pred" : "hasExactSynonym", "val" : "protein biosynthetic process" }, { "pred" : "hasExactSynonym", "val" : "protein formation" }, { "pred" : "hasExactSynonym", "val" : "protein synthesis" }, { "pred" : "hasExactSynonym", "val" : "protein translation" } ], "xrefs" : [ { "val" : "Wikipedia:Translation_(genetics)" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0006416" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0006453" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0043037" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006413", "lbl" : "translational initiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.", "xrefs" : [ "ISBN:019879276X" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "biopolymerisation" }, { "pred" : "hasBroadSynonym", "val" : "biopolymerization" }, { "pred" : "hasBroadSynonym", "val" : "protein synthesis initiation" }, { "pred" : "hasExactSynonym", "val" : "translation initiation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0006440" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0006454" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006414", "lbl" : "translational elongation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.", "xrefs" : [ "GOC:ems" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "protein synthesis elongation" }, { "pred" : "hasExactSynonym", "val" : "translation elongation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0006442" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0006455" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006415", "lbl" : "translational termination", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).", "xrefs" : [ "GOC:hjd", "ISBN:019879276X" ] }, "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "protein synthesis termination" }, { "pred" : "hasExactSynonym", "val" : "translation termination" }, { "pred" : "hasExactSynonym", "val" : "translational complex disassembly" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0006443" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0006456" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006417", "lbl" : "regulation of translation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.", "xrefs" : [ "GOC:isa_complete" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "regulation of protein anabolism" }, { "pred" : "hasExactSynonym", "val" : "regulation of protein biosynthesis" }, { "pred" : "hasExactSynonym", "val" : "regulation of protein formation" }, { "pred" : "hasExactSynonym", "val" : "regulation of protein synthesis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0006445" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006446", "lbl" : "regulation of translational initiation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of translational initiation.", "xrefs" : [ "GOC:go_curators" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006448", "lbl" : "regulation of translational elongation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate, extent or accuracy of translational elongation.", "xrefs" : [ "GOC:go_curators" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006449", "lbl" : "regulation of translational termination", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of translational termination.", "xrefs" : [ "GOC:go_curators" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006518", "lbl" : "peptide metabolic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.", "xrefs" : [ "GOC:go_curators" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "peptide metabolism" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006520", "lbl" : "amino acid metabolic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups.", "xrefs" : [ "ISBN:0198506732" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cellular amino acid metabolic process" }, { "pred" : "hasExactSynonym", "val" : "cellular amino acid metabolism" }, { "pred" : "hasRelatedSynonym", "val" : "amino acid and derivative metabolism" }, { "pred" : "hasRelatedSynonym", "val" : "cellular amino acid and derivative metabolic process" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0006519" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006521", "lbl" : "regulation of cellular amino acid metabolic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids.", "xrefs" : [ "GOC:go_curators" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "regulation of amino acid metabolism" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006576", "lbl" : "biogenic amine metabolic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.", "xrefs" : [ "GOC:jl", "ISBN:0395825172" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "biogenic amine metabolism" }, { "pred" : "hasExactSynonym", "val" : "cellular biogenic amine metabolic process" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006584", "lbl" : "catecholamine metabolic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.", "xrefs" : [ "GOC:jl", "ISBN:0198506732" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "catecholamine metabolism" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006586", "lbl" : "indolalkylamine metabolic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.", "xrefs" : [ "GOC:curators" ] }, "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "indolamine metabolic process" }, { "pred" : "hasBroadSynonym", "val" : "indolamine metabolism" }, { "pred" : "hasExactSynonym", "val" : "indolalkylamine metabolism" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006606", "lbl" : "protein import into nucleus", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed movement of a protein from the cytoplasm to the nucleus.", "xrefs" : [ "GOC:jl" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "establishment of protein localization to nucleus", "xrefs" : [ "GOC:mah" ] }, { "pred" : "hasExactSynonym", "val" : "protein import into cell nucleus" }, { "pred" : "hasExactSynonym", "val" : "protein nucleus import" }, { "pred" : "hasExactSynonym", "val" : "protein transport from cytoplasm to nucleus" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006611", "lbl" : "protein export from nucleus", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed movement of a protein from the nucleus into the cytoplasm.", "xrefs" : [ "GOC:jl" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein export from cell nucleus" }, { "pred" : "hasExactSynonym", "val" : "protein export out of nucleus" }, { "pred" : "hasExactSynonym", "val" : "protein transport from nucleus to cytoplasm" }, { "pred" : "hasExactSynonym", "val" : "protein-nucleus export" }, { "pred" : "hasRelatedSynonym", "val" : "copper-induced protein export from nucleus", "xrefs" : [ "GOC:al" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0097349" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006629", "lbl" : "lipid metabolic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.", "xrefs" : [ "GOC:ma" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_euk_cellular_processes_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_plant_ribbon", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "lipid metabolism" } ], "xrefs" : [ { "val" : "Wikipedia:Lipid_metabolism" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006694", "lbl" : "steroid biosynthetic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.", "xrefs" : [ "GOC:go_curators" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "steroid anabolism" }, { "pred" : "hasExactSynonym", "val" : "steroid biosynthesis" }, { "pred" : "hasExactSynonym", "val" : "steroid formation" }, { "pred" : "hasExactSynonym", "val" : "steroid synthesis" }, { "pred" : "hasExactSynonym", "val" : "steroidogenesis" } ], "xrefs" : [ { "val" : "Wikipedia:Steroid_metabolisms#Steroid_biosynthesis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006790", "lbl" : "sulfur compound metabolic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "sulfur metabolism" }, { "pred" : "hasExactSynonym", "val" : "sulphur metabolic process" }, { "pred" : "hasExactSynonym", "val" : "sulphur metabolism" } ], "xrefs" : [ { "val" : "Wikipedia:Sulfur_metabolism" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006810", "lbl" : "transport", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein.", "xrefs" : [ "GOC:dos", "GOC:dph", "GOC:jl", "GOC:mah" ] }, "comments" : [ "Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_plant_ribbon", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_prokaryote_ribbon" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "single-organism transport" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "jl" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2012-12-13T16:25:32Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0015457" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0015460" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0044765" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006811", "lbl" : "monoatomic ion transport", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "ion transport" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006836", "lbl" : "neurotransmitter transport", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "sodium:neurotransmitter transport" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006837", "lbl" : "serotonin transport", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.", "xrefs" : [ "GOC:ai" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006846", "lbl" : "acetate transport", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.", "xrefs" : [ "GOC:krc" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006847", "lbl" : "plasma membrane acetate transport", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed movement of acetate across a plasma membrane.", "xrefs" : [ "GOC:ai" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006858", "lbl" : "extracellular transport", "type" : "CLASS", "meta" : { "definition" : { "val" : "The transport of substances that occurs outside cells.", "xrefs" : [ "GOC:go_curators" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006860", "lbl" : "extracellular amino acid transport", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed extracellular movement of amino acids.", "xrefs" : [ "GOC:ai" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006865", "lbl" : "amino acid transport", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0006866" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006869", "lbl" : "lipid transport", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.", "xrefs" : [ "ISBN:0198506732" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006886", "lbl" : "intracellular protein transport", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.", "xrefs" : [ "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "copper-induced intracellular protein transport", "xrefs" : [ "GOC:al" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0032779" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006887", "lbl" : "exocytosis", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for example of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.", "xrefs" : [ "GOC:mah", "ISBN:0716731363", "PMID:22323285" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "vesicle exocytosis" }, { "pred" : "hasRelatedSynonym", "val" : "nonselective vesicle exocytosis" } ], "xrefs" : [ { "val" : "Wikipedia:Exocytosis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0016194" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0016195" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006892", "lbl" : "post-Golgi vesicle-mediated transport", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles.", "xrefs" : [ "GOC:ai", "GOC:mah" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "post-Golgi transport" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006893", "lbl" : "Golgi to plasma membrane transport", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis.", "xrefs" : [ "ISBN:0716731363" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Golgi to plasma membrane vesicle-mediated transport" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006896", "lbl" : "Golgi to vacuole transport", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed movement of substances from the Golgi to the vacuole.", "xrefs" : [ "GOC:ai" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Golgi to vacuole vesicle-mediated transport" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006903", "lbl" : "vesicle targeting", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo.", "xrefs" : [ "GOC:mah", "PMID:17335816" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006906", "lbl" : "vesicle fusion", "type" : "CLASS", "meta" : { "definition" : { "val" : "Fusion of the membrane of a transport vesicle with its target membrane.", "xrefs" : [ "GOC:jid" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006913", "lbl" : "nucleocytoplasmic transport", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed movement of molecules between the nucleus and the cytoplasm.", "xrefs" : [ "GOC:go_curators" ] }, "comments" : [ "Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane, and is not traversed." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pombe" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "nucleocytoplasmic shuttling" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0000063" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006915", "lbl" : "apoptotic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.", "xrefs" : [ "GOC:cjm", "GOC:dhl", "GOC:ecd", "GOC:go_curators", "GOC:mtg_apoptosis", "GOC:tb", "ISBN:0198506732", "PMID:18846107", "PMID:21494263" ] }, "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cell suicide" }, { "pred" : "hasBroadSynonym", "val" : "cellular suicide" }, { "pred" : "hasExactSynonym", "val" : "apoptotic cell death", "xrefs" : [ "GOC:sl" ] }, { "pred" : "hasExactSynonym", "val" : "apoptotic programmed cell death" }, { "pred" : "hasExactSynonym", "val" : "programmed cell death by apoptosis" }, { "pred" : "hasNarrowSynonym", "val" : "activation of apoptosis" }, { "pred" : "hasNarrowSynonym", "val" : "apoptosis" }, { "pred" : "hasNarrowSynonym", "val" : "apoptosis signaling" }, { "pred" : "hasNarrowSynonym", "val" : "apoptotic program", "xrefs" : [ "GOC:add" ] }, { "pred" : "hasNarrowSynonym", "val" : "type I programmed cell death" }, { "pred" : "hasRelatedSynonym", "val" : "apoptosis activator activity" }, { "pred" : "hasRelatedSynonym", "val" : "caspase-dependent programmed cell death" }, { "pred" : "hasRelatedSynonym", "val" : "commitment to apoptosis" }, { "pred" : "hasRelatedSynonym", "val" : "induction of apoptosis" }, { "pred" : "hasRelatedSynonym", "val" : "induction of apoptosis by p53" }, { "pred" : "hasRelatedSynonym", "val" : "signaling (initiator) caspase activity" } ], "xrefs" : [ { "val" : "Wikipedia:Apoptosis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0006917" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0008632" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006921", "lbl" : "cellular component disassembly involved in execution phase of apoptosis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis.", "xrefs" : [ "GOC:dph", "GOC:mah", "GOC:mtg_apoptosis", "GOC:tb" ] }, "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cellular component disassembly involved in apoptotic process" }, { "pred" : "hasBroadSynonym", "val" : "disassembly of cell structures" }, { "pred" : "hasNarrowSynonym", "val" : "cellular component disassembly involved in apoptosis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006936", "lbl" : "muscle contraction", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.", "xrefs" : [ "GOC:ef", "GOC:mtg_muscle", "ISBN:0198506732" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], "xrefs" : [ { "val" : "Wikipedia:Muscle_contraction" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006937", "lbl" : "regulation of muscle contraction", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of muscle contraction.", "xrefs" : [ "GOC:go_curators" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006939", "lbl" : "smooth muscle contraction", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.", "xrefs" : [ "GOC:ef", "GOC:jl", "GOC:mtg_muscle", "ISBN:0198506732" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "visceral muscle contraction" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006940", "lbl" : "regulation of smooth muscle contraction", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of smooth muscle contraction.", "xrefs" : [ "GOC:go_curators" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006941", "lbl" : "striated muscle contraction", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope.", "xrefs" : [ "GOC:jl", "GOC:mtg_muscle", "ISBN:0198506732" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "sarcomeric muscle contraction" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006942", "lbl" : "regulation of striated muscle contraction", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of striated muscle contraction.", "xrefs" : [ "GOC:go_curators" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006949", "lbl" : "syncytium formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division.", "xrefs" : [ "ISBN:0198506732" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006950", "lbl" : "response to stress", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).", "xrefs" : [ "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_plant_ribbon" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "response to abiotic stress" }, { "pred" : "hasRelatedSynonym", "val" : "response to biotic stress" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006952", "lbl" : "defense response", "type" : "CLASS", "meta" : { "definition" : { "val" : "Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.", "xrefs" : [ "GOC:go_curators" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "defence response" }, { "pred" : "hasExactSynonym", "val" : "physiological defense response" }, { "pred" : "hasRelatedSynonym", "val" : "antimicrobial peptide activity" }, { "pred" : "hasRelatedSynonym", "val" : "defense/immunity protein activity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0002217" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0042829" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006954", "lbl" : "inflammatory response", "type" : "CLASS", "meta" : { "definition" : { "val" : "The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.", "xrefs" : [ "GO_REF:0000022", "ISBN:0198506732" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_generic" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "inflammation" } ], "xrefs" : [ { "val" : "Wikipedia:Inflammation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006996", "lbl" : "organelle organization", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.", "xrefs" : [ "GOC:mah" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "organelle organisation" }, { "pred" : "hasExactSynonym", "val" : "single organism organelle organization", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "organelle organization and biogenesis", "xrefs" : [ "GOC:dph", "GOC:jl", "GOC:mah" ] }, { "pred" : "hasRelatedSynonym", "val" : "single-organism organelle organization" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "jl" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2013-12-19T15:25:51Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:1902589" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006997", "lbl" : "nucleus organization", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.", "xrefs" : [ "GOC:dph", "GOC:ems", "GOC:jl", "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "nuclear organisation" }, { "pred" : "hasExactSynonym", "val" : "nuclear organization" }, { "pred" : "hasRelatedSynonym", "val" : "nuclear morphology" }, { "pred" : "hasRelatedSynonym", "val" : "nuclear organization and biogenesis", "xrefs" : [ "GOC:mah" ] }, { "pred" : "hasRelatedSynonym", "val" : "nucleus organization and biogenesis", "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0048287" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006998", "lbl" : "nuclear envelope organization", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope.", "xrefs" : [ "GOC:dph", "GOC:ems", "GOC:jl", "GOC:mah" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "nuclear envelope organisation", "xrefs" : [ "GOC:mah" ] }, { "pred" : "hasRelatedSynonym", "val" : "nuclear envelope organization and biogenesis", "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007000", "lbl" : "nucleolus organization", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus.", "xrefs" : [ "GOC:dph", "GOC:jid", "GOC:jl", "GOC:mah" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "nucleolus organisation" }, { "pred" : "hasRelatedSynonym", "val" : "nucleolus organization and biogenesis", "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007009", "lbl" : "plasma membrane organization", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane.", "xrefs" : [ "GOC:dph", "GOC:jl", "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "plasma membrane organisation" }, { "pred" : "hasRelatedSynonym", "val" : "plasma membrane organization and biogenesis", "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007010", "lbl" : "cytoskeleton organization", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.", "xrefs" : [ "GOC:dph", "GOC:jl", "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cytoskeleton organisation" }, { "pred" : "hasRelatedSynonym", "val" : "cytoskeletal organization and biogenesis", "xrefs" : [ "GOC:mah" ] }, { "pred" : "hasRelatedSynonym", "val" : "cytoskeletal regulator activity" }, { "pred" : "hasRelatedSynonym", "val" : "cytoskeleton organization and biogenesis", "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007015", "lbl" : "actin filament organization", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.", "xrefs" : [ "GOC:mah" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "actin filament organisation" }, { "pred" : "hasNarrowSynonym", "val" : "regulation of actin filament localization" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007017", "lbl" : "microtubule-based process", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.", "xrefs" : [ "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007018", "lbl" : "microtubule-based movement", "type" : "CLASS", "meta" : { "definition" : { "val" : "A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.", "xrefs" : [ "GOC:cjm", "ISBN:0815316194" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007019", "lbl" : "microtubule depolymerization", "type" : "CLASS", "meta" : { "definition" : { "val" : "The removal of tubulin heterodimers from one or both ends of a microtubule.", "xrefs" : [ "ISBN:0815316194" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "microtubule disassembly" }, { "pred" : "hasExactSynonym", "val" : "microtubule shortening" }, { "pred" : "hasNarrowSynonym", "val" : "microtubule catastrophe", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, { "pred" : "hasNarrowSynonym", "val" : "microtubule depolymerization during nuclear congression" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007020", "lbl" : "microtubule nucleation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).", "xrefs" : [ "GOC:go_curators", "ISBN:0815316194", "PMID:12517712" ] }, "xrefs" : [ { "val" : "Wikipedia:Microtubule_nucleation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007026", "lbl" : "negative regulation of microtubule depolymerization", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.", "xrefs" : [ "GOC:mah", "ISBN:0815316194" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of microtubule depolymerization" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of microtubule depolymerization" }, { "pred" : "hasExactSynonym", "val" : "downregulation of microtubule depolymerization" }, { "pred" : "hasExactSynonym", "val" : "microtubule stabilization" }, { "pred" : "hasExactSynonym", "val" : "negative regulation of microtubule disassembly" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of microtubule depolymerization" }, { "pred" : "hasNarrowSynonym", "val" : "microtubule rescue", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of microtubule catastrophe", "xrefs" : [ "GOC:dph", "GOC:tb" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007027", "lbl" : "negative regulation of axonemal microtubule depolymerization", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme.", "xrefs" : [ "GOC:dph", "GOC:mah" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "axonemal microtubule stabilization" }, { "pred" : "hasRelatedSynonym", "val" : "negative regulation of microtubule depolymerization in axoneme", "xrefs" : [ "GOC:dph" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007028", "lbl" : "cytoplasm organization", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.", "xrefs" : [ "GOC:curators", "GOC:dph", "GOC:jl", "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cytoplasm organisation" }, { "pred" : "hasRelatedSynonym", "val" : "cytoplasm organization and biogenesis", "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007030", "lbl" : "Golgi organization", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.", "xrefs" : [ "GOC:dph", "GOC:jl", "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Golgi apparatus organization" }, { "pred" : "hasExactSynonym", "val" : "Golgi organisation" }, { "pred" : "hasRelatedSynonym", "val" : "Golgi organization and biogenesis", "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007033", "lbl" : "vacuole organization", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.", "xrefs" : [ "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "vacuole organisation" }, { "pred" : "hasNarrowSynonym", "val" : "vacuolar assembly", "xrefs" : [ "GOC:mah" ] }, { "pred" : "hasRelatedSynonym", "val" : "vacuole biogenesis", "xrefs" : [ "GOC:mah" ] }, { "pred" : "hasRelatedSynonym", "val" : "vacuole organization and biogenesis", "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0044086" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007034", "lbl" : "vacuolar transport", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed movement of substances into, out of or within a vacuole.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007043", "lbl" : "cell-cell junction assembly", "type" : "CLASS", "meta" : { "definition" : { "val" : "The aggregation, arrangement and bonding together of a set of components to form a junction between cells.", "xrefs" : [ "GOC:ai" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "intercellular junction assembly" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007049", "lbl" : "cell cycle", "type" : "CLASS", "meta" : { "definition" : { "val" : "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.", "xrefs" : [ "GOC:go_curators", "GOC:mtg_cell_cycle" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_plant_ribbon" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell-division cycle" } ], "xrefs" : [ { "val" : "Wikipedia:Cell_cycle" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007059", "lbl" : "chromosome segregation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.", "xrefs" : [ "GOC:jl", "GOC:mah", "GOC:mtg_cell_cycle", "GOC:vw" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "chromosome division" }, { "pred" : "hasRelatedSynonym", "val" : "chromosome transmission" } ], "xrefs" : [ { "val" : "Wikipedia:Chromosome_segregation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007076", "lbl" : "mitotic chromosome condensation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells.", "xrefs" : [ "GOC:mah", "ISBN:0815316194" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007077", "lbl" : "mitotic nuclear membrane disassembly", "type" : "CLASS", "meta" : { "definition" : { "val" : "The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis.", "xrefs" : [ "GOC:bf", "PMID:32848252" ] }, "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "NEB" }, { "pred" : "hasBroadSynonym", "val" : "local NEB" }, { "pred" : "hasBroadSynonym", "val" : "nuclear envelope breakdown" }, { "pred" : "hasExactSynonym", "val" : "mitotic nuclear envelope breakdown" }, { "pred" : "hasRelatedSynonym", "val" : "mitotic nuclear envelope catabolism" }, { "pred" : "hasRelatedSynonym", "val" : "mitotic nuclear envelope degradation" }, { "pred" : "hasRelatedSynonym", "val" : "mitotic nuclear envelope disassembly" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007088", "lbl" : "regulation of mitotic nuclear division", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of mitosis.", "xrefs" : [ "GOC:go_curators" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "regulation of mitosis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007097", "lbl" : "nuclear migration", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed movement of the nucleus to a specific location within a cell.", "xrefs" : [ "GOC:ai" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "establishment of position of nucleus" }, { "pred" : "hasExactSynonym", "val" : "nuclear movement" }, { "pred" : "hasExactSynonym", "val" : "nuclear positioning" }, { "pred" : "hasExactSynonym", "val" : "nucleus migration" }, { "pred" : "hasExactSynonym", "val" : "nucleus positioning" }, { "pred" : "hasExactSynonym", "val" : "positioning of nucleus" }, { "pred" : "hasRelatedSynonym", "val" : "establishment of cell nucleus localization" }, { "pred" : "hasRelatedSynonym", "val" : "establishment of localization of nucleus" }, { "pred" : "hasRelatedSynonym", "val" : "establishment of nucleus localisation", "xrefs" : [ "GOC:mah" ] }, { "pred" : "hasRelatedSynonym", "val" : "establishment of nucleus localization" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0040023" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007113", "lbl" : "endomitotic cell cycle", "type" : "CLASS", "meta" : { "definition" : { "val" : "A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.", "xrefs" : [ "GOC:curators", "GOC:dos", "GOC:expert_vm" ] }, "comments" : [ "Note that this term should not be confused with 'abortive mitotic cell cycle ; GO:0033277'. Although abortive mitosis is sometimes called endomitosis, GO:0033277 refers to a process in which a mitotic spindle forms and chromosome separation begins." ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "endomitosis" } ], "xrefs" : [ { "val" : "Wikipedia:Mitosis#Endomitosis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007143", "lbl" : "female meiotic nuclear division", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.", "xrefs" : [ "GOC:dph", "GOC:ems", "GOC:mah", "GOC:vw" ] }, "comments" : [ "Note that female germ lines can be found in female or hermaphroditic organisms, so this term can be used to annotate gene products from hermaphrodites such as those of C. elegans. See also the biological process term 'meiotic nuclear division; GO:0140013'." ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "female meiosis" }, { "pred" : "hasBroadSynonym", "val" : "female meiotic division" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007154", "lbl" : "cell communication", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.", "xrefs" : [ "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "xrefs" : [ { "val" : "Wikipedia:Cell_signaling" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007163", "lbl" : "establishment or maintenance of cell polarity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.", "xrefs" : [ "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "cell polarity", "xrefs" : [ "GOC:mah", "GOC:vw" ] }, { "pred" : "hasRelatedSynonym", "val" : "establishment and/or maintenance of cell polarity" }, { "pred" : "hasRelatedSynonym", "val" : "establishment and/or maintenance of cell polarization" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0030012" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0030467" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007165", "lbl" : "signal transduction", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.", "xrefs" : [ "GOC:go_curators", "GOC:mtg_signaling_feb11" ] }, "comments" : [ "Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_plant_ribbon" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "signaling cascade" }, { "pred" : "hasNarrowSynonym", "val" : "signalling cascade" }, { "pred" : "hasRelatedSynonym", "val" : "signaling pathway" }, { "pred" : "hasRelatedSynonym", "val" : "signalling pathway" } ], "xrefs" : [ { "val" : "Wikipedia:Signal_transduction" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0023014" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0023015" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0023016" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0023033" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0023045" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007267", "lbl" : "cell-cell signaling", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.", "xrefs" : [ "GOC:dos", "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell-cell signalling" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007268", "lbl" : "chemical synaptic transmission", "type" : "CLASS", "meta" : { "definition" : { "val" : "The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.", "xrefs" : [ "GOC:jl", "MeSH:D009435" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_synapse" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "signal transmission across a synapse" }, { "pred" : "hasBroadSynonym", "val" : "synaptic transmission" }, { "pred" : "hasRelatedSynonym", "val" : "neurotransmission", "xrefs" : [ "GOC:dph" ] } ], "xrefs" : [ { "val" : "Wikipedia:Neurotransmission" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007269", "lbl" : "neurotransmitter secretion", "type" : "CLASS", "meta" : { "definition" : { "val" : "The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission.", "xrefs" : [ "GOC:dph" ] }, "comments" : [ "A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_synapse" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neurotransmitter release" }, { "pred" : "hasExactSynonym", "val" : "neurotransmitter secretory pathway" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0010554" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007271", "lbl" : "synaptic transmission, cholinergic", "type" : "CLASS", "meta" : { "definition" : { "val" : "The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.", "xrefs" : [ "GOC:dos", "Wikipedia:Cholinergic" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cholinergic synaptic transmission" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007272", "lbl" : "ensheathment of neurons", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment.", "xrefs" : [ "GOC:dgh", "GOC:dph", "GOC:tb" ] }, "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "ionic insulation of neurons by glial cells" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007275", "lbl" : "multicellular organism development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).", "xrefs" : [ "GOC:dph", "GOC:ems", "GOC:isa_complete", "GOC:tb" ] }, "comments" : [ "Note that this term was 'developmental process'." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007276", "lbl" : "gamete generation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell.", "xrefs" : [ "GOC:ems", "GOC:mtg_sensu" ] }, "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "gametogenesis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0009552" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007281", "lbl" : "germ cell development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.", "xrefs" : [ "GOC:go_curators" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "germ-cell development" }, { "pred" : "hasNarrowSynonym", "val" : "gametogenesis" }, { "pred" : "hasNarrowSynonym", "val" : "primordial germ cell development" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007292", "lbl" : "female gamete generation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction.", "xrefs" : [ "GOC:dph", "ISBN:0198506732" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007293", "lbl" : "germarium-derived egg chamber formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster.", "xrefs" : [ "GOC:mtg_sensu", "ISBN:0879694238" ] }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007308", "lbl" : "oocyte construction", "type" : "CLASS", "meta" : { "definition" : { "val" : "The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster.", "xrefs" : [ "GOC:dph", "GOC:ems", "GOC:mtg_sensu", "GOC:tb", "ISBN:0198506732" ] }, "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "oocyte arrangement", "xrefs" : [ "GOC:dph", "GOC:tb" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0048110" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007338", "lbl" : "single fertilization", "type" : "CLASS", "meta" : { "definition" : { "val" : "The union of male and female gametes to form a zygote.", "xrefs" : [ "GOC:ems", "GOC:mtg_sensu" ] }, "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "zygote biosynthesis" }, { "pred" : "hasRelatedSynonym", "val" : "zygote formation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007343", "lbl" : "egg activation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm.", "xrefs" : [ "GOC:bf", "PMID:9630751" ] }, "xrefs" : [ { "val" : "Wikipedia:Egg_activation" } ], "basicPropertyValues" : [ {