Gene,Gene ID,Reproductive RNA (nTPM),Taxonomy ID,Reference,Nominated,Restriction passed,Coverage adequate,Safety veto,Normal IHC positive,Normal RNA failure,High normal RNA,Variable,Antibody concern,Cell RNA concern,Reproductive protein,Previous category,Previous selection detail,Previous selection reason,Expression reasons,Accepted normal protein,Unresolved normal evidence,Reproductive admission,Reviewed affirmative support,Review IDs,Evidence sources,Accepted evidence,Unresolved evidence,Rejected evidence,Previous member,Expression forbidden,Previous selection policy,Expression category,Expression detail,Expression reason,Expression policy,Clinical qualification,Clinical evidence sources,Clinical qualification limits,Selection basis,Change,Core RNA (nTPM),Core tissues measured,Core comparator maximum (nTPM),Core comparator tissues measured,Testis RNA (nTPM),Ovary RNA (nTPM),Placenta RNA (nTPM),Other reproductive RNA (nTPM),Other reproductive tissues measured,Nonreproductive maximum (nTPM),Nonreproductive tissues measured,Core / comparator maximum,Core comparator maximum is zero,Cancer-germline papers,Cancer-placental papers,Publication classes,Nomination DOIs,Nomination source tags,Tumor RNA positive,Tumor IHC positive,Tumor RNA cohorts measured,Tumor IHC groups measured,Positive RNA cohorts,Positive IHC groups,Tumor RNA support only TGCT,Tumor RNA threshold (pTPM),Tumor minimum samples,Tumor minimum prevalence,Tumor IHC minimum cases,Reviewed classes,Reviewed admission role,Reviewed admission rationale,Membership sources,Membership limitations,Identity scope,Member,Established route,Consensus route,Expression route,Core expression route,Other reproductive route,Evidence tier,Classes,Membership reason,Membership policy,Change from 215,Prior cell audit: cta_excluded,Prior cell audit: reference_review,Prior cell audit: no_source_records,Cell RNA audit coverage,Risk assessment,Normal expression flags,Developmental atlas coverage,Donor uncertainty,Normal breadth manageable lower,Normal breadth manageable upper,Normal breadth manageable missing_weight,Normal breadth protected lower,Normal breadth protected upper,Normal breadth protected missing_weight,Normal breadth vital lower,Normal breadth vital upper,Normal breadth vital missing_weight
YBX2,ENSG00000006047,535.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Unsafe,Normal,Accepted published protein in non-permitted normal cells,Accepted published protein in non-permitted normal cells,True,False,True,False,review-20261025-YBX2,https://pubmed.ncbi.nlm.nih.gov/16479255/,review-20261025-YBX2,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Normal,Accepted published protein in non-permitted normal cells,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,535.8,3,7.0,47,535.8,0.3,0.0,3.1,8,7.0,39,76.54285714285713,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Accepted normal protein|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09132266165847125,0.09132266165847125,0.0,0.10400954638944121,0.4117018540817489,0.3076923076923077,0.20190258757245297,0.40778494051362946,0.20588235294117652
SOX30,ENSG00000039600,78.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000039600,https://v23.proteinatlas.org/ENSG00000039600-SOX30/tissue/primary+data,,ihc-20261025-ENSG00000039600,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,78.4,3,0.9,47,78.4,0.1,0.1,0.9,8,0.7,39,87.11111111111111,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|HNSC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA,breast cancer|carcinoid|cervical cancer|ovarian cancer|prostate cancer|renal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.017005680776983688,0.017005680776983688,0.0,0.012370143517684503,0.3200624512099922,0.3076923076923077,0.023809523809523808,0.22969187675070032,0.20588235294117652
MAGEC2,ENSG00000046774,19.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,review-20261025-MAGEC2,https://pubmed.ncbi.nlm.nih.gov/12920247/,,review-20261025-MAGEC2,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,19.0,3,0.0,47,19.0,0.0,0.0,0.0,8,0.0,39,,True,5,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1186/s12967-024-04918-0|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Seager2024_CTA|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|GBM:validation|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|READ:TCGA|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,liver cancer|melanoma|skin cancer,False,1,3,0.05,2,,Context only,"User excluded non-MAGEA4 MAGE genes from positive controls and automatic reviewed admission; retain citations and concerns, and evaluate ordinary publication/expression routes.",https://pubmed.ncbi.nlm.nih.gov/10699956/,Antibody evidence is distinct from functional T-cell recognition; current normal-expression concerns remain.,Locus,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
MOV10L1,ENSG00000073146,41.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000073146,https://v23.proteinatlas.org/ENSG00000073146-MOV10L1/tissue/primary+data,,ihc-20261025-ENSG00000073146,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,41.4,3,4.2,47,41.4,2.9,0.5,4.2,8,2.2,39,9.857142857142856,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUSC:TCGA|LUSC:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,liver cancer|lung cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02487286176606565,0.02487286176606565,0.0,0.043696134879349376,0.3513884425716571,0.3076923076923077,0.19346382043076707,0.39934617337194356,0.20588235294117652
FNDC8,ENSG00000073598,86.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000073598,https://v23.proteinatlas.org/ENSG00000073598-FNDC8/tissue/primary+data,,ihc-20261025-ENSG00000073598,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,86.5,3,0.1,47,86.5,0.0,0.0,0.1,8,0.1,39,865.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|LIHC:validation|PRAD:TCGA|UCEC:TCGA,cervical cancer|prostate cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
FKBP6,ENSG00000077800,56.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000077800,https://v23.proteinatlas.org/ENSG00000077800-FKBP6/tissue/primary+data,,ihc-20261025-ENSG00000077800,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,56.9,3,0.3,47,56.9,0.3,0.0,0.3,8,0.2,39,189.66666666666666,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,CESC:TCGA|HNSC:TCGA|LUSC:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009823335274703943,0.009823335274703943,0.0,0.00500345767400236,0.31269576536631005,0.3076923076923077,0.02549656226126814,0.23137891520244466,0.20588235294117652
SMC1B,ENSG00000077935,30.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000077935,https://v23.proteinatlas.org/ENSG00000077935-SMC1B/tissue/primary+data,,ihc-20261025-ENSG00000077935,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,30.2,3,0.3,47,30.2,0.0,0.1,0.0,8,0.3,39,100.66666666666667,False,5,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Bruggeman2018_GC|Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|HNSC:TCGA|KIRC:validation|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.007672634271099744,0.21355498721227625,0.20588235294117652
ACR,ENSG00000100312,84.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000100312,https://v23.proteinatlas.org/ENSG00000100312-ACR/tissue/primary+data,,ihc-20261025-ENSG00000100312,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,84.3,3,2.9,47,84.3,0.3,0.1,1.9,8,2.9,39,29.06896551724138,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|COAD:validation|KIRC:TCGA|KIRC:validation|LIHC:validation|OV:TCGA|OV:validation|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.11109680984187348,0.11109680984187348,0.0,0.028373869720023568,0.3360661774123313,0.3076923076923077,0.16258224534086604,0.3684645982820426,0.20588235294117652
SEL1L2,ENSG00000101251,6.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000101251,https://v23.proteinatlas.org/ENSG00000101251-SEL1L2/tissue/primary+data,,ihc-20261025-ENSG00000101251,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.9,3,0.1,47,6.9,0.1,0.0,0.1,8,0.1,39,69.0,False,1,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.005602240896358543,0.21148459383753507,0.20588235294117652
PRSS54,ENSG00000103023,40.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000103023,https://v23.proteinatlas.org/ENSG00000103023-PRSS54/tissue/primary+data,,ihc-20261025-ENSG00000103023,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,40.2,3,0.1,47,40.2,0.0,0.0,0.0,8,0.1,39,402.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,GBM:TCGA|GBM:validation|LIHC:validation|PRAD:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0017507002801120447,0.20763305322128855,0.20588235294117652
ADAM2,ENSG00000104755,37.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000104755,https://v23.proteinatlas.org/ENSG00000104755-ADAM2/tissue/primary+data,,ihc-20261025-ENSG00000104755,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,37.0,3,0.0,47,37.0,0.0,0.0,0.0,8,0.0,39,,True,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CGB3,ENSG00000104827,9.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000104827,https://v23.proteinatlas.org/ENSG00000104827-CGB3/tissue/primary+data,,ihc-20261025-ENSG00000104827,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.5,3,2.2,47,0.3,0.0,9.5,0.1,8,2.2,39,4.3181818181818175,False,0,1,Cancer-placental|Cancer-reproductive,10.1038/s41467-020-19141-w|10.1038/s41467-021-22695-y,Bradley2020_CPA|Gong2021_placenta_PC|Gong2021_reproductive_PC,True,False,29,20,BLCA:TCGA|CESC:TCGA|COAD:validation|HNSC:TCGA|LUAD:TCGA|PAAD:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0037424236260830655,0.3114347313183908,0.3076923076923077,0.06557168321874204,0.2714540361599186,0.20588235294117652
DKKL1,ENSG00000104901,335.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000104901,https://v23.proteinatlas.org/ENSG00000104901-DKKL1/tissue/primary+data,,ihc-20261025-ENSG00000104901,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,335.2,3,1.2,47,335.2,1.1,0.3,1.2,8,0.9,39,279.3333333333333,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.028619557096742364,0.028619557096742364,0.0,0.039004921650382725,0.3466972293426904,0.3076923076923077,0.1031118343689999,0.3089941873101764,0.20588235294117652
RSPH6A,ENSG00000104941,28.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000104941,https://v23.proteinatlas.org/ENSG00000104941-RSPH6A/tissue/primary+data,,ihc-20261025-ENSG00000104941,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,28.9,3,2.7,47,28.9,0.0,0.0,0.5,8,2.7,39,10.703703703703702,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,OV:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04251968503937009,0.04251968503937009,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
LGALS13,ENSG00000105198,10.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,review-20261025-LGALS13,https://pubmed.ncbi.nlm.nih.gov/10527825/ | https://pubmed.ncbi.nlm.nih.gov/19497882/,,review-20261025-LGALS13,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.9,3,0.2,47,0.3,0.0,10.9,0.0,8,0.2,39,54.5,False,1,0,Cancer-germline|Cancer-placental|Cancer-reproductive,10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_placenta_PC|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_testis_biased,True,False,31,0,TGCT:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.0037242169595110767,0.2096065699006876,0.20588235294117652
SPAM1,ENSG00000106304,16.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000106304,https://v23.proteinatlas.org/ENSG00000106304-SPAM1/tissue/primary+data,,ihc-20261025-ENSG00000106304,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.9,3,0.4,47,16.9,0.0,0.1,0.0,8,0.4,39,42.24999999999999,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.015345268542199487,0.221227621483376,0.20588235294117652
FBXO24,ENSG00000106336,79.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000106336,https://v23.proteinatlas.org/ENSG00000106336-FBXO24/tissue/primary+data,,ihc-20261025-ENSG00000106336,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,79.0,3,1.4,47,79.0,0.9,0.6,1.4,8,1.3,39,56.42857142857143,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.057094285242044046,0.057094285242044046,0.0,0.058009086433242346,0.36570139412555003,0.3076923076923077,0.17973981947767115,0.38562217241884766,0.20588235294117652
HDGFL1,ENSG00000112273,88.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000112273,https://v23.proteinatlas.org/ENSG00000112273-HDGFL1/tissue/primary+data,,ihc-20261025-ENSG00000112273,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,88.5,3,0.4,47,88.5,0.1,0.0,0.1,8,0.4,39,221.25,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.009803921568627453,0.21568627450980396,0.20588235294117652
MORC1,ENSG00000114487,15.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000114487,https://v23.proteinatlas.org/ENSG00000114487-MORC1/tissue/primary+data,,ihc-20261025-ENSG00000114487,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.5,3,0.3,47,15.5,0.1,0.1,0.3,8,0.3,39,51.66666666666667,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,GBM:validation|LUSC:TCGA|SKCM:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.014643604477364066,0.22052595741854059,0.20588235294117652
SPACA1,ENSG00000118434,40.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000118434,https://v23.proteinatlas.org/ENSG00000118434-SPACA1/tissue/primary+data,,ihc-20261025-ENSG00000118434,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,40.7,3,0.1,47,40.7,0.0,0.0,0.0,8,0.1,39,407.0,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,LIHC:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
EQTN,ENSG00000120160,36.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000120160,https://v23.proteinatlas.org/ENSG00000120160-EQTN/tissue/primary+data,,ihc-20261025-ENSG00000120160,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,36.7,3,0.6,47,36.7,0.5,0.0,0.5,8,0.6,39,61.16666666666667,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,20,COAD:validation|GBM:validation|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.015686274509803925,0.015686274509803925,0.0,0.014810854578173457,0.32250316227048115,0.3076923076923077,0.05471348770581507,0.2605958406469916,0.20588235294117652
TEX14,ENSG00000121101,26.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000121101,https://v23.proteinatlas.org/ENSG00000121101-TEX14/tissue/primary+data,,ihc-20261025-ENSG00000121101,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,26.2,3,1.7,47,26.2,0.3,0.1,0.2,8,1.7,39,15.411764705882353,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:TCGA|BRCA:validation|GBM:validation|LIHC:validation|SKCM:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.00788196466705494,0.00788196466705494,0.0,0.005044136191677176,0.31273644388398486,0.3076923076923077,0.08978790212805557,0.29567025506923206,0.20588235294117652
ABCC11,ENSG00000121270,45.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Unsafe,Normal,Accepted published protein in non-permitted normal cells,Accepted published protein in non-permitted normal cells,True,False,True,False,review-20261025-ABCC11,https://pubmed.ncbi.nlm.nih.gov/16359813/,review-20261025-ABCC11,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Normal,Accepted published protein in non-permitted normal cells,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.3,3,45.3,47,2.3,0.0,0.0,45.3,8,1.6,39,0.05077262693156733,False,1,0,Cancer-germline,10.1038/s41388-018-0357-2,Bruggeman2018_GC,True,False,31,0,BRCA:TCGA|BRCA:validation|GBM:validation|LIHC:TCGA|LIHC:validation|PAAD:validation|PRAD:TCGA|SKCM:TCGA|TGCT:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,False,True,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Accepted normal protein|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013630683456695184,0.013630683456695184,0.0,0.0,0.3076923076923077,0.3076923076923077,0.038411148385572934,0.24429350132674946,0.20588235294117652
ACTRT1,ENSG00000123165,4.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Unsafe,Normal,Accepted published protein in non-permitted normal cells,Accepted published protein in non-permitted normal cells,True,False,True,False,review-20261025-ACTRT1,https://pubmed.ncbi.nlm.nih.gov/33972689/ | https://pubmed.ncbi.nlm.nih.gov/28869610/,review-20261025-ACTRT1,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Normal,Accepted published protein in non-permitted normal cells,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.0,3,0.0,47,4.0,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Accepted normal protein|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CTCFL,ENSG00000124092,10.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000124092,https://v23.proteinatlas.org/ENSG00000124092-CTCFL/tissue/primary+data,,ihc-20261025-ENSG00000124092,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.8,3,0.9,47,10.8,0.1,0.3,0.4,8,0.9,39,12.0,False,6,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Jamin2021_core|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|HNSC:TCGA|KIRC:TCGA|KIRP:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02513469100030669,0.02513469100030669,0.0,0.017336675751535614,0.32502898344384334,0.3076923076923077,0.09030173606855854,0.29618408900973503,0.20588235294117652
MAGEA10,ENSG00000124260,9.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000124260,https://v23.proteinatlas.org/ENSG00000124260-MAGEA10/tissue/primary+data,,ihc-20261025-ENSG00000124260,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,https://pubmed.ncbi.nlm.nih.gov/35086946/ | https://pubmed.ncbi.nlm.nih.gov/35372008/,A single response with a complicated regimen is not comparable evidence to repeated responses; normal-antibody conflicts remain unresolved.,Not selected,Unchanged,9.1,3,0.4,47,2.5,0.0,9.1,0.0,8,0.4,39,22.749999999999996,False,5,0,Cancer-germline|Cancer-placental|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1186/s12967-024-04918-0|10.1371/journal.pgen.1011734,Carter2023_CT|Chang2019_TGCT|Gong2021_placenta_PC|Gong2021_reproductive_PC|Jamin2021_CT|Jamin2021_core|Loriot2025_S1|Seager2024_CTA|Wang2016_CT,True,True,31,20,BLCA:TCGA|CESC:TCGA|COAD:validation|HNSC:TCGA|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|glioma|liver cancer|lung cancer|melanoma|pancreatic cancer|skin cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,Context only,"User excluded non-MAGEA4 MAGE genes from positive controls and automatic reviewed admission; retain citations and concerns, and evaluate ordinary publication/expression routes.",https://pubmed.ncbi.nlm.nih.gov/10699956/,Clinical efficacy is not a membership condition; current normal-antibody findings remain unresolved.,Locus,True,False,True,True,True,False,Publication consensus,Cancer-germline|Cancer-placental,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013632901751713633,0.013632901751713633,0.0,0.0037424236260830655,0.3114347313183908,0.3076923076923077,0.01502557544757033,0.22090792838874684,0.20588235294117652
IRGC,ENSG00000124449,145.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000124449,https://v23.proteinatlas.org/ENSG00000124449-IRGC/tissue/primary+data,,ihc-20261025-ENSG00000124449,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,145.5,3,0.1,47,145.5,0.0,0.0,0.1,8,0.1,39,1455.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.003851540616246498,0.209733893557423,0.20588235294117652
PSG8,ENSG00000124467,6.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000124467,https://v23.proteinatlas.org/ENSG00000124467-PSG8/tissue/primary+data,,ihc-20261025-ENSG00000124467,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.3,3,0.2,47,0.0,0.0,6.3,0.0,8,0.2,39,31.499999999999996,False,1,0,Cancer-germline|Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_placenta_PC|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TCP11,ENSG00000124678,331.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000124678,https://v23.proteinatlas.org/ENSG00000124678-TCP11/tissue/primary+data,,ihc-20261025-ENSG00000124678,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,331.3,3,0.9,47,331.3,0.7,0.0,0.9,8,0.5,39,368.11111111111114,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|HNSC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.017515642967011635,0.017515642967011635,0.0,0.015996221740536918,0.32368852943284465,0.3076923076923077,0.06088119042083236,0.26676354336200886,0.20588235294117652
PRDM7,ENSG00000126856,1.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000126856,https://v23.proteinatlas.org/ENSG00000126856-PRDM7/tissue/primary+data,,ihc-20261025-ENSG00000126856,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.0,3,0.0,47,1.0,0.0,0.0,0.0,8,0.0,39,,True,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,SKCM:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
VCY1B,ENSG00000129862,55.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000129862,https://v23.proteinatlas.org/ENSG00000129862-VCY1B/tissue/primary+data,,ihc-20261025-ENSG00000129862,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,55.6,3,0.0,47,55.6,0.0,0.4,0.0,8,0.0,39,,True,1,0,Cancer-germline,10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Loriot2025_S1|daSilva2017_testis_biased,True,False,30,20,LIHC:TCGA|SKCM:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
VCY,ENSG00000129864,58.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000129864,https://v23.proteinatlas.org/ENSG00000129864-VCY/tissue/primary+data,,ihc-20261025-ENSG00000129864,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,58.3,3,0.0,47,58.3,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline,10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Loriot2025_S1|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|LIHC:TCGA|SKCM:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
ACSBG2,ENSG00000130377,125.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000130377,https://v23.proteinatlas.org/ENSG00000130377-ACSBG2/tissue/primary+data,,ihc-20261025-ENSG00000130377,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,125.5,3,0.5,47,125.5,0.0,0.0,0.3,8,0.5,39,251.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|GBM:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005901766647252961,0.005901766647252961,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.013343519225872168,0.2192258721670487,0.20588235294117652
PKDREJ,ENSG00000130943,3.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000130943,https://v23.proteinatlas.org/ENSG00000130943-PKDREJ/tissue/primary+data,,ihc-20261025-ENSG00000130943,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.3,3,0.5,47,3.3,0.1,0.0,0.1,8,0.5,39,6.6,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1136/jitc-2023-007935,Carter2023_CT|Chang2019_TGCT|Wang2016_CT,True,False,31,20,BRCA:validation|COAD:validation|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013484205563413485,0.013484205563413485,0.0,0.007566204287515765,0.31525851197982346,0.3076923076923077,0.03889876108546185,0.24478111402663838,0.20588235294117652
RHOXF2,ENSG00000131721,10.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000131721,https://v23.proteinatlas.org/ENSG00000131721-RHOXF2/tissue/primary+data,,ihc-20261025-ENSG00000131721,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.7,3,0.2,47,10.7,0.0,0.0,0.0,8,0.2,39,53.49999999999999,False,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,30,20,COAD:validation|READ:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.0,0.3076923076923077,0.3076923076923077,0.007098293862999745,0.21298064680417625,0.20588235294117652
TEX15,ENSG00000133863,11.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000133863,https://v23.proteinatlas.org/ENSG00000133863-TEX15/tissue/primary+data,,ihc-20261025-ENSG00000133863,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11.8,3,6.5,47,11.8,0.4,0.0,6.5,8,5.1,39,1.8153846153846156,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|CESC:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|LUSC:validation|PAAD:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.006068726355611602,0.31376103404791933,0.3076923076923077,0.06504126194519191,0.2709236148863684,0.20588235294117652
USP26,ENSG00000134588,0.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000134588,https://v23.proteinatlas.org/ENSG00000134588-USP26/tissue/primary+data,,ihc-20261025-ENSG00000134588,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.4,3,0.1,47,0.4,0.0,0.0,0.0,8,0.1,39,4.0,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
DMRT1,ENSG00000137090,26.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000137090,https://v23.proteinatlas.org/ENSG00000137090-DMRT1/tissue/primary+data,,ihc-20261025-ENSG00000137090,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,26.1,3,0.3,47,26.1,0.0,0.0,0.0,8,0.3,39,87.00000000000001,False,5,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Jamin2021_core|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,CESC:TCGA|HNSC:TCGA|KICH:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.0,0.3076923076923077,0.3076923076923077,0.000959079283887468,0.206841432225064,0.20588235294117652
PLCZ1,ENSG00000139151,41.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,review-20261025-PLCZ1 | review-20261025-PLCZ1-RNA,https://www.cuhk.edu.hk/ecbrc/cliparts/Publication%20list/Lancet2003.pdf,,review-20261025-PLCZ1-RNA,review-20261025-PLCZ1,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,41.1,3,1.7,47,41.1,0.0,0.0,0.1,8,1.7,39,24.176470588235297,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,GBM:validation|LUAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.029059829059829064,0.029059829059829064,0.0,0.009731730018615265,0.317424037710923,0.3076923076923077,0.017952635599694424,0.22383498854087094,0.20588235294117652
GOLGA6D,ENSG00000140478,11.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000140478,https://v23.proteinatlas.org/ENSG00000140478-GOLGA6D/tissue/primary+data,,ihc-20261025-ENSG00000140478,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11.7,3,0.7,47,11.7,0.0,0.0,0.0,8,0.7,39,16.714285714285715,False,2,0,Cancer-germline|Cancer-reproductive,10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,BRCA:validation|LIHC:TCGA|LIHC:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.020948278301219477,0.226830631242396,0.20588235294117652
CHCT1,ENSG00000141371,131.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000141371,https://v23.proteinatlas.org/ENSG00000141371-CHCT1/tissue/primary+data,,ihc-20261025-ENSG00000141371,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,131.5,3,0.6,47,131.5,0.1,0.0,0.3,8,0.6,39,219.16666666666669,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|KIRC:TCGA|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,prostate cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.019309448281860087,0.019309448281860087,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.043688089404201935,0.24957044234537845,0.20588235294117652
DMRTB1,ENSG00000143006,60.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000143006,https://v23.proteinatlas.org/ENSG00000143006-DMRTB1/tissue/primary+data,,ihc-20261025-ENSG00000143006,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,60.9,3,0.8,47,60.9,0.0,0.0,0.8,8,0.1,39,76.125,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,TGCT:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
HHIPL2,ENSG00000143512,4.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000143512,https://v23.proteinatlas.org/ENSG00000143512-HHIPL2/tissue/primary+data,,ihc-20261025-ENSG00000143512,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.7,3,1.9,47,4.7,0.1,0.0,0.8,8,1.9,39,2.473684210526316,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|GBM:validation|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:validation|PRAD:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.035854341736694675,0.035854341736694675,0.0,0.012250045036930285,0.319942352729238,0.3076923076923077,0.014675435391547923,0.22055778833272444,0.20588235294117652
NUP210L,ENSG00000143552,25.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000143552,https://v23.proteinatlas.org/ENSG00000143552-NUP210L/tissue/primary+data,,ihc-20261025-ENSG00000143552,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,25.8,3,0.6,47,25.8,0.1,0.0,0.3,8,0.6,39,43.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,COAD:validation|GBM:validation|LUAD:TCGA|LUAD:validation|READ:validation,breast cancer|melanoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005901766647252961,0.005901766647252961,0.0,0.003663003663003663,0.31135531135531136,0.3076923076923077,0.03788996595901967,0.24377231890019618,0.20588235294117652
SPATA16,ENSG00000144962,57.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000144962,https://v23.proteinatlas.org/ENSG00000144962-SPATA16/tissue/primary+data,,ihc-20261025-ENSG00000144962,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,57.8,3,0.0,47,57.8,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CABS1,ENSG00000145309,103.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000145309,https://v23.proteinatlas.org/ENSG00000145309-CABS1/tissue/primary+data,,ihc-20261025-ENSG00000145309,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,103.4,3,3.9,47,103.4,0.0,0.0,0.1,8,3.9,39,26.512820512820515,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,30,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.030303030303030304,0.337995337995338,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
AKAP4,ENSG00000147081,190.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000147081,https://v23.proteinatlas.org/ENSG00000147081-AKAP4/tissue/primary+data,,ihc-20261025-ENSG00000147081,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,190.2,3,0.1,47,190.2,0.0,0.0,0.1,8,0.0,39,1901.9999999999998,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,READ:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
ACTL7B,ENSG00000148156,115.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000148156,https://v23.proteinatlas.org/ENSG00000148156-ACTL7B/tissue/primary+data,,ihc-20261025-ENSG00000148156,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,115.5,3,0.1,47,115.5,0.0,0.0,0.1,8,0.0,39,1155.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
C20orf144,ENSG00000149609,172.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000149609,https://v23.proteinatlas.org/ENSG00000149609-C20orf144/tissue/primary+data,,ihc-20261025-ENSG00000149609,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,172.7,3,0.1,47,172.7,0.0,0.0,0.1,8,0.0,39,1726.9999999999998,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|LIHC:validation,testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
BOLL,ENSG00000152430,47.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000152430,https://v23.proteinatlas.org/ENSG00000152430-BOLL/tissue/primary+data,,ihc-20261025-ENSG00000152430,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,47.5,3,3.6,47,47.5,0.0,0.0,0.0,8,3.6,39,13.194444444444445,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|CESC:TCGA|KICH:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.013698630136986304,0.321390937829294,0.3076923076923077,0.03781512605042017,0.2436974789915967,0.20588235294117652
DDX4,ENSG00000152670,145.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000152670,https://v23.proteinatlas.org/ENSG00000152670-DDX4/tissue/primary+data,,ihc-20261025-ENSG00000152670,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,145.2,3,0.4,47,145.2,1.2,0.0,0.1,8,0.4,39,362.99999999999994,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,TGCT:TCGA,testis cancer,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.0037424236260830655,0.3114347313183908,0.3076923076923077,0.03219489376778379,0.2380772467089603,0.20588235294117652
TGIF2LX,ENSG00000153779,8.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000153779,https://v23.proteinatlas.org/ENSG00000153779-TGIF2LX/tissue/primary+data,,ihc-20261025-ENSG00000153779,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.5,3,0.0,47,8.5,0.0,0.0,0.0,8,0.0,39,,True,5,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,LIHC:TCGA|LIHC:validation|LUSC:TCGA|LUSC:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
ASZ1,ENSG00000154438,10.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000154438,https://v23.proteinatlas.org/ENSG00000154438-ASZ1/tissue/primary+data,,ihc-20261025-ENSG00000154438,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.4,3,0.0,47,10.4,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,LUAD:TCGA|LUAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
ODF1,ENSG00000155087,386.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000155087,https://v23.proteinatlas.org/ENSG00000155087-ODF1/tissue/primary+data,,ihc-20261025-ENSG00000155087,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,386.0,3,0.7,47,386.0,0.0,0.0,0.3,8,0.7,39,551.4285714285714,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,False,True,31,20,,carcinoid,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.019465219113556708,0.22534757205473321,0.20588235294117652
MAGEC1,ENSG00000155495,7.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000155495,https://v23.proteinatlas.org/ENSG00000155495-MAGEC1/tissue/primary+data,,ihc-20261025-ENSG00000155495,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.1,3,0.1,47,7.1,0.0,0.0,0.0,8,0.1,39,70.99999999999999,False,5,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,BLCA:TCGA|BRCA:validation|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,Context only,"User excluded non-MAGEA4 MAGE genes from positive controls and automatic reviewed admission; retain citations and concerns, and evaluate ordinary publication/expression routes.",https://pubmed.ncbi.nlm.nih.gov/9618514/|https://pubmed.ncbi.nlm.nih.gov/10699956/,Serological discovery does not by itself demonstrate locus-specific HLA presentation or safety.,Locus,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
MAGEA8,ENSG00000156009,12.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000156009,https://v23.proteinatlas.org/ENSG00000156009-MAGEA8/tissue/primary+data,,ihc-20261025-ENSG00000156009,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,12.8,3,0.2,47,1.6,0.1,12.8,0.1,8,0.2,39,64.0,False,4,0,Cancer-germline|Cancer-placental|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_placenta_PC|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:validation|LIHC:TCGA|LIHC:validation|LUAD:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,glioma|head and neck cancer|lung cancer|lymphoma|melanoma|renal cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline|Cancer-placental,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0020690094219505983,0.2079513623631271,0.20588235294117652
NAA11,ENSG00000156269,6.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000156269,https://v23.proteinatlas.org/ENSG00000156269-NAA11/tissue/primary+data,,ihc-20261025-ENSG00000156269,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.0,3,0.4,47,6.0,0.0,4.0,0.1,8,0.4,39,15.0,False,5,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BLCA:TCGA|COAD:validation|LIHC:TCGA|LIHC:validation|LUSC:TCGA|OV:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA,cervical cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline|Cancer-placental,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.008403361344537816,0.21428571428571433,0.20588235294117652
LYZL4,ENSG00000157093,50.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000157093,https://v23.proteinatlas.org/ENSG00000157093-LYZL4/tissue/primary+data,,ihc-20261025-ENSG00000157093,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,50.7,3,1.0,47,50.7,0.0,0.0,0.0,8,1.0,39,50.7,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation,liver cancer|ovarian cancer|pancreatic cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.013518589253883372,0.2194009421950599,0.20588235294117652
GOLGA6A,ENSG00000159289,14.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000159289,https://v23.proteinatlas.org/ENSG00000159289-GOLGA6A/tissue/primary+data,,ihc-20261025-ENSG00000159289,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,14.7,3,2.2,47,14.7,0.1,0.0,0.1,8,2.2,39,6.681818181818181,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,BRCA:validation|LIHC:TCGA|PAAD:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.0,0.3076923076923077,0.3076923076923077,0.04373567608861727,0.2496180290297938,0.20588235294117652
PDHA2,ENSG00000163114,58.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000163114,https://v23.proteinatlas.org/ENSG00000163114-PDHA2/tissue/primary+data,,ihc-20261025-ENSG00000163114,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,58.4,3,0.0,47,58.4,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
PDCL2,ENSG00000163440,63.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000163440,https://v23.proteinatlas.org/ENSG00000163440-PDCL2/tissue/primary+data,,ihc-20261025-ENSG00000163440,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,63.3,3,0.3,47,63.3,0.0,0.0,0.0,8,0.3,39,211.0,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,GBM:validation|OV:TCGA|OV:validation|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.003663003663003663,0.31135531135531136,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
CCDC158,ENSG00000163749,33.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Unsafe,Normal,Accepted published protein in non-permitted normal cells,Accepted published protein in non-permitted normal cells,True,False,True,False,review-20261025-CCDC158,https://pubmed.ncbi.nlm.nih.gov/39319391/,review-20261025-CCDC158,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Normal,Accepted published protein in non-permitted normal cells,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,33.3,3,1.6,47,33.3,0.0,0.0,1.1,8,1.6,39,20.812499999999996,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:TCGA|BRCA:validation|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:validation|PAAD:validation|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Accepted normal protein|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03253265908133165,0.03253265908133165,0.0,0.009700261907071493,0.3173925695993792,0.3076923076923077,0.09676025878071914,0.30264261172189566,0.20588235294117652
DNAJC5G,ENSG00000163793,45.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000163793,https://v23.proteinatlas.org/ENSG00000163793-DNAJC5G/tissue/primary+data,,ihc-20261025-ENSG00000163793,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,22.1,3,45.7,47,22.1,0.2,0.0,45.7,8,2.2,39,0.48358862144420134,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1371/journal.pgen.1011734,Chang2019_TGCT|Loriot2025_S2|Wang2016_CT,True,False,31,20,BLCA:TCGA|CESC:TCGA|COAD:validation|GBM:validation|KICH:TCGA|KIRP:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.05188439011968424,0.2577667430608608,0.20588235294117652
FAM170A,ENSG00000164334,13.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000164334,https://v23.proteinatlas.org/ENSG00000164334-FAM170A/tissue/primary+data,,ihc-20261025-ENSG00000164334,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.9,3,0.2,47,13.9,0.0,0.0,0.0,8,0.2,39,69.5,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation,colorectal cancer|melanoma|skin cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.003469569646040234,0.20935192258721674,0.20588235294117652
GDF9,ENSG00000164404,8.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000164404,https://v23.proteinatlas.org/ENSG00000164404-GDF9/tissue/primary+data,,ihc-20261025-ENSG00000164404,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.7,3,3.5,47,8.7,1.1,0.2,3.5,8,1.6,39,2.4857142857142853,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PRAD:TCGA|SKCM:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0612972422099951,0.0612972422099951,0.0,0.055738661790697995,0.3634309694830057,0.3076923076923077,0.19705907143532841,0.40294142437650493,0.20588235294117652
PRKACG,ENSG00000165059,23.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000165059,https://v23.proteinatlas.org/ENSG00000165059-PRKACG/tissue/primary+data,,ihc-20261025-ENSG00000165059,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,23.9,3,0.0,47,23.9,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
PRSS37,ENSG00000165076,40.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000165076,https://v23.proteinatlas.org/ENSG00000165076-PRSS37/tissue/primary+data,,ihc-20261025-ENSG00000165076,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,40.1,3,0.4,47,40.1,0.0,0.0,0.0,8,0.4,39,100.25,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009672505712109673,0.009672505712109673,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0017507002801120447,0.20763305322128855,0.20588235294117652
PASD1,ENSG00000166049,15.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000166049,https://v23.proteinatlas.org/ENSG00000166049-PASD1/tissue/primary+data,,ihc-20261025-ENSG00000166049,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.6,3,0.0,47,15.6,0.0,0.0,0.0,8,0.0,39,,True,5,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,SKCM:TCGA|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TMCO5A,ENSG00000166069,106.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000166069,https://v23.proteinatlas.org/ENSG00000166069-TMCO5A/tissue/primary+data,,ihc-20261025-ENSG00000166069,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,106.5,3,0.6,47,106.5,0.0,0.0,0.3,8,0.6,39,177.5,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,False,True,31,20,,glioma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.010656010656010656,0.31834831834831834,0.3076923076923077,0.0003501400560224089,0.20623249299719892,0.20588235294117652
SPATA19,ENSG00000166118,130.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000166118,https://v23.proteinatlas.org/ENSG00000166118-SPATA19/tissue/primary+data,,ihc-20261025-ENSG00000166118,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,130.9,3,0.2,47,130.9,0.0,0.0,0.1,8,0.2,39,654.5,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,31,20,,prostate cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.0070664629488158895,0.2129488158899924,0.20588235294117652
SUN5,ENSG00000167098,43.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000167098,https://v23.proteinatlas.org/ENSG00000167098-SUN5/tissue/primary+data,,ihc-20261025-ENSG00000167098,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,43.6,3,0.0,47,43.6,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TBC1D21,ENSG00000167139,48.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000167139,https://v23.proteinatlas.org/ENSG00000167139-TBC1D21/tissue/primary+data,,ihc-20261025-ENSG00000167139,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,48.3,3,0.0,47,48.3,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
GOLGA6C,ENSG00000167195,9.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000167195,https://v23.proteinatlas.org/ENSG00000167195-GOLGA6C/tissue/primary+data,,ihc-20261025-ENSG00000167195,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.7,3,3.7,47,9.7,0.1,0.0,0.1,8,3.7,39,2.6216216216216215,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,LIHC:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.00788196466705494,0.00788196466705494,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.07655719642386975,0.2824395493650463,0.20588235294117652
TSPY2,ENSG00000168757,7.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000168757,https://v23.proteinatlas.org/ENSG00000168757-TSPY2/tissue/primary+data,,ihc-20261025-ENSG00000168757,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.4,3,0.0,47,7.4,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_testis_biased,True,True,31,20,LIHC:TCGA|LIHC:validation|TGCT:TCGA,testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
VCX3A,ENSG00000169059,53.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000169059,https://v23.proteinatlas.org/ENSG00000169059-VCX3A/tissue/primary+data,,ihc-20261025-ENSG00000169059,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,53.3,3,0.4,47,53.3,0.1,0.0,0.3,8,0.4,39,133.24999999999997,False,5,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:validation|HNSC:TCGA|KICH:TCGA|LIHC:TCGA|LUAD:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.00788196466705494,0.00788196466705494,0.0,0.0037831021437578823,0.3114754098360656,0.3076923076923077,0.036762629953167036,0.24264498289434355,0.20588235294117652
RBMY1F,ENSG00000169800,3.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000169800,https://v23.proteinatlas.org/ENSG00000169800-RBMY1F/tissue/primary+data,,ihc-20261025-ENSG00000169800,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.1,3,0.0,47,3.1,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
GARIN3,ENSG00000170613,30.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000170613,https://v23.proteinatlas.org/ENSG00000170613-GARIN3/tissue/primary+data,,ihc-20261025-ENSG00000170613,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,30.7,3,0.0,47,30.7,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
RBMXL2,ENSG00000170748,34.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000170748,https://v23.proteinatlas.org/ENSG00000170748-RBMXL2/tissue/primary+data,,ihc-20261025-ENSG00000170748,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,34.9,3,0.1,47,34.9,0.0,0.0,0.0,8,0.1,39,348.99999999999994,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,TGCT:TCGA,testis cancer,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.009803921568627449,0.21568627450980396,0.20588235294117652
PSG6,ENSG00000170848,48.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000170848,https://v23.proteinatlas.org/ENSG00000170848-PSG6/tissue/primary+data,,ihc-20261025-ENSG00000170848,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,48.0,3,1.4,47,0.0,0.0,48.0,0.0,8,1.4,39,34.285714285714285,False,0,0,Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_placenta_PC|Gong2021_reproductive_PC,True,False,31,20,COAD:validation|LUAD:validation|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.0,0.3076923076923077,0.3076923076923077,0.030969607094174567,0.23685196003535108,0.20588235294117652
PGK2,ENSG00000170950,194.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000170950,https://v23.proteinatlas.org/ENSG00000170950-PGK2/tissue/primary+data,,ihc-20261025-ENSG00000170950,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,194.1,3,0.3,47,194.1,0.0,0.0,0.3,8,0.0,39,647.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BRCA:validation,breast cancer|renal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
PLAC1,ENSG00000170965,27.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000170965,https://v23.proteinatlas.org/ENSG00000170965-PLAC1/tissue/primary+data,,ihc-20261025-ENSG00000170965,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,27.0,3,0.2,47,0.9,0.3,27.0,0.2,8,0.2,39,135.0,False,1,1,Cancer-germline|Cancer-placental|Cancer-reproductive,10.1038/ncomms10499|10.1038/s41467-020-19141-w|10.1038/s41467-021-22695-y,Bradley2020_CPA|Gong2021_placenta_PC|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|HNSC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,Cancer-placental,Membership support,Reviewed reproductive/developmental and tumor association supports biological membership; not a safety or approval claim.,https://pubmed.ncbi.nlm.nih.gov/17909063/,Tumor biology alone does not establish HLA presentation or product safety; adult normal conflicts persist.,Locus,True,True,False,True,True,False,Established,Cancer-placental,Reviewed reproductive/developmental and tumor association,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.005602240896358543,0.21148459383753507,0.20588235294117652
DDI1,ENSG00000170967,24.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000170967,https://v23.proteinatlas.org/ENSG00000170967-DDI1/tissue/primary+data,,ihc-20261025-ENSG00000170967,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,24.7,3,0.0,47,24.7,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
SPACA5,ENSG00000171489,13.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000171489,https://v23.proteinatlas.org/ENSG00000171489-SPACA5/tissue/primary+data,,ihc-20261025-ENSG00000171489,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.7,3,0.5,47,13.7,0.1,0.0,0.2,8,0.5,39,27.4,False,1,0,Cancer-germline,10.1038/ncomms10499,Wang2016_CT,True,False,31,20,BRCA:validation|COAD:validation|GBM:TCGA|READ:validation|STAD:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.017405774190864465,0.017405774190864465,0.0,0.007525525769840948,0.31521783346214866,0.3076923076923077,0.0380068035119186,0.2438891564530951,0.20588235294117652
MROH2B,ENSG00000171495,29.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000171495,https://v23.proteinatlas.org/ENSG00000171495-MROH2B/tissue/primary+data,,ihc-20261025-ENSG00000171495,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,29.3,3,0.1,47,29.3,0.0,0.0,0.0,8,0.1,39,293.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,29,20,,breast cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
KLF17,ENSG00000171872,8.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000171872,https://v23.proteinatlas.org/ENSG00000171872-KLF17/tissue/primary+data,,ihc-20261025-ENSG00000171872,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.1,3,1.1,47,8.1,0.0,0.0,0.7,8,1.1,39,7.363636363636362,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BRCA:validation|GBM:TCGA|GBM:validation|SKCM:TCGA|TGCT:TCGA,lymphoma|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.02309124251116685,0.33078355020347455,0.3076923076923077,0.04944429384657089,0.2553266467877474,0.20588235294117652
LDHAL6B,ENSG00000171989,39.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000171989,https://v23.proteinatlas.org/ENSG00000171989-LDHAL6B/tissue/primary+data,,ihc-20261025-ENSG00000171989,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,39.5,3,0.3,47,39.5,0.0,0.0,0.2,8,0.3,39,131.66666666666669,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|COAD:validation|READ:validation|STAD:TCGA,thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013630683456695184,0.013630683456695184,0.0,0.008786559817760243,0.31647886751006793,0.3076923076923077,0.03469846436598355,0.24058081730716008,0.20588235294117652
SPMIP9,ENSG00000172073,82.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000172073,https://v23.proteinatlas.org/ENSG00000172073-SPMIP9/tissue/primary+data,,ihc-20261025-ENSG00000172073,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,82.6,3,0.0,47,82.6,0.0,0.1,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_testis_biased,True,True,29,20,LIHC:TCGA|TGCT:TCGA,cervical cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
GLIPR1L1,ENSG00000173401,31.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000173401,https://v23.proteinatlas.org/ENSG00000173401-GLIPR1L1/tissue/primary+data,,ihc-20261025-ENSG00000173401,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,31.6,3,0.5,47,31.6,0.2,0.0,0.3,8,0.5,39,63.2,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:TCGA|BRCA:validation|COAD:validation|GBM:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:validation|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.023192189497158087,0.023192189497158087,0.0,0.012368206445414273,0.32006051413772196,0.3076923076923077,0.06115202998195325,0.26703438292312975,0.20588235294117652
IHO1,ENSG00000173421,25.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000173421,https://v23.proteinatlas.org/ENSG00000173421-IHO1/tissue/primary+data,,ihc-20261025-ENSG00000173421,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,25.7,3,3.1,47,25.7,3.6,0.9,1.7,8,3.1,39,8.29032258064516,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:validation|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|OV:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.08650332288571816,0.08650332288571816,0.0,0.046009675979309314,0.35370198367161704,0.3076923076923077,0.14058356570517166,0.3464659186463482,0.20588235294117652
SPATA3,ENSG00000173699,171.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000173699,https://v23.proteinatlas.org/ENSG00000173699-SPATA3/tissue/primary+data,,ihc-20261025-ENSG00000173699,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,171.8,3,0.3,47,171.8,0.0,0.1,0.2,8,0.3,39,572.6666666666667,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,GBM:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005940594059405941,0.005940594059405941,0.0,0.00500345767400236,0.31269576536631005,0.3076923076923077,0.022936249598653688,0.22881860253983022,0.20588235294117652
CBY2,ENSG00000174015,96.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000174015,https://v23.proteinatlas.org/ENSG00000174015-CBY2/tissue/primary+data,,ihc-20261025-ENSG00000174015,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,96.3,3,0.2,47,96.3,0.0,0.0,0.1,8,0.2,39,481.49999999999994,False,5,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|HNSC:TCGA|LUAD:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
UBQLN3,ENSG00000175520,154.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000175520,https://v23.proteinatlas.org/ENSG00000175520-UBQLN3/tissue/primary+data,,ihc-20261025-ENSG00000175520,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,154.3,3,0.2,47,154.3,0.0,0.0,0.2,8,0.0,39,771.5,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,GBM:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
HORMAD2,ENSG00000176635,22.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000176635,https://v23.proteinatlas.org/ENSG00000176635-HORMAD2/tissue/primary+data,,ihc-20261025-ENSG00000176635,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,22.2,3,2.8,47,22.2,0.0,0.0,0.0,8,2.8,39,7.928571428571429,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,GBM:validation|LIHC:TCGA|LIHC:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.03985230455818691,0.24573465749936343,0.20588235294117652
FMR1NB,ENSG00000176988,56.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000176988,https://v23.proteinatlas.org/ENSG00000176988-FMR1NB/tissue/primary+data,,ihc-20261025-ENSG00000176988,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,56.5,3,0.1,47,56.5,0.0,0.0,0.1,8,0.1,39,565.0,False,5,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0042016806722689065,0.2100840336134454,0.20588235294117652
CETN1,ENSG00000177143,130.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000177143,https://v23.proteinatlas.org/ENSG00000177143-CETN1/tissue/primary+data,,ihc-20261025-ENSG00000177143,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,130.6,3,0.1,47,130.6,0.0,0.0,0.1,8,0.0,39,1305.9999999999998,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_testis_biased,True,False,31,20,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
SPACA4,ENSG00000177202,114.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000177202,https://v23.proteinatlas.org/ENSG00000177202-SPACA4/tissue/primary+data,,ihc-20261025-ENSG00000177202,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,114.5,3,3.5,47,114.5,0.0,0.0,0.8,8,3.5,39,32.714285714285715,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|HNSC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.023008849557522124,0.023008849557522124,0.0,0.10040036693921896,0.40809267463152665,0.3076923076923077,0.06997583141202508,0.2758581843532016,0.20588235294117652
FAM187B,ENSG00000177558,66.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000177558,https://v23.proteinatlas.org/ENSG00000177558-FAM187B/tissue/primary+data,,ihc-20261025-ENSG00000177558,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,66.8,3,0.2,47,66.8,0.0,0.0,0.1,8,0.2,39,333.99999999999994,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0035014005602240893,0.2093837535014006,0.20588235294117652
TEX44,ENSG00000177673,148.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000177673,https://v23.proteinatlas.org/ENSG00000177673-TEX44/tissue/primary+data,,ihc-20261025-ENSG00000177673,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,148.2,3,0.1,47,148.2,0.0,0.0,0.1,8,0.0,39,1481.9999999999998,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,False,False,29,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CAPZA3,ENSG00000177938,177.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000177938,https://v23.proteinatlas.org/ENSG00000177938-CAPZA3/tissue/primary+data,,ihc-20261025-ENSG00000177938,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,177.5,3,2.1,47,177.5,0.0,0.0,0.8,8,2.1,39,84.52380952380952,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|LIHC:validation|PAAD:TCGA|PAAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03471074380165289,0.03471074380165289,0.0,0.015342580916351408,0.32303488860865914,0.3076923076923077,0.041666666666666664,0.24754901960784317,0.20588235294117652
CIMAP1A,ENSG00000177947,9.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000177947,https://v23.proteinatlas.org/ENSG00000177947-CIMAP1A/tissue/primary+data,,ihc-20261025-ENSG00000177947,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.1,3,0.4,47,9.1,0.0,0.0,0.0,8,0.4,39,22.749999999999996,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,31,20,,urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.004901960784313726,0.21078431372549025,0.20588235294117652
TSPYL6,ENSG00000178021,20.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000178021,https://v23.proteinatlas.org/ENSG00000178021-TSPYL6/tissue/primary+data,,ihc-20261025-ENSG00000178021,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,20.8,3,0.1,47,20.8,0.0,0.0,0.0,8,0.1,39,208.0,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,TGCT:TCGA,testis cancer,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.008753501400560222,0.21463585434173674,0.20588235294117652
C10orf53,ENSG00000178645,38.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000178645,https://v23.proteinatlas.org/ENSG00000178645-C10orf53/tissue/primary+data,,ihc-20261025-ENSG00000178645,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,38.5,3,0.3,47,38.5,0.0,0.0,0.3,8,0.3,39,128.33333333333334,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:validation|HNSC:TCGA|LUSC:TCGA|PRAD:TCGA|READ:validation|SKCM:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005825242718446602,0.005825242718446602,0.0,0.0,0.3076923076923077,0.3076923076923077,0.015157050962677561,0.22103940390385407,0.20588235294117652
MEIOC,ENSG00000180336,46.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000180336,https://v23.proteinatlas.org/ENSG00000180336-MEIOC/tissue/primary+data,,ihc-20261025-ENSG00000180336,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,46.2,3,3.3,47,46.2,0.3,0.1,0.3,8,3.3,39,14.000000000000002,False,4,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|KICH:TCGA|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.028483194788163378,0.028483194788163378,0.0,0.0244224861160345,0.3321147938083422,0.3076923076923077,0.1623974133289763,0.3682797662701528,0.20588235294117652
C11orf42,ENSG00000180878,24.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000180878,https://v23.proteinatlas.org/ENSG00000180878-C11orf42/tissue/primary+data,,ihc-20261025-ENSG00000180878,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,24.7,3,1.5,47,24.7,0.1,0.1,0.3,8,1.5,39,16.466666666666665,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,True,31,20,BRCA:validation|COAD:validation|KIRC:validation|READ:validation|STAD:TCGA,thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03393009377664109,0.03393009377664109,0.0,0.013549820530254164,0.3212421282225619,0.3076923076923077,0.05739977573589314,0.2632821286770697,0.20588235294117652
SAGE1,ENSG00000181433,4.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000181433,https://v23.proteinatlas.org/ENSG00000181433-SAGE1/tissue/primary+data,,ihc-20261025-ENSG00000181433,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.7,3,0.2,47,4.7,0.0,0.0,0.0,8,0.2,39,23.5,False,5,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|GBM:validation|HNSC:TCGA|LIHC:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|SKCM:TCGA|STAD:TCGA|UCEC:TCGA,breast cancer|lung cancer|skin cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.01021772345301757,0.2161000763941941,0.20588235294117652
EDDM3B,ENSG00000181552,2502.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000181552,https://v23.proteinatlas.org/ENSG00000181552-EDDM3B/tissue/primary+data,,ihc-20261025-ENSG00000181552,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.0,3,2502.0,47,0.0,0.0,0.0,2502.0,8,0.0,39,0.0,False,1,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:TCGA|BRCA:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,False,True,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
FTMT,ENSG00000181867,52.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Unsafe,Normal,Accepted published protein in non-permitted normal cells,Accepted published protein in non-permitted normal cells,True,False,True,False,review-20261025-FTMT,https://pubmed.ncbi.nlm.nih.gov/28386150/ | https://pubmed.ncbi.nlm.nih.gov/38988693/,review-20261025-FTMT,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Normal,Accepted published protein in non-permitted normal cells,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,52.6,3,0.0,47,52.6,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Accepted normal protein|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TEX19,ENSG00000182459,30.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000182459,https://v23.proteinatlas.org/ENSG00000182459-TEX19/tissue/primary+data,,ihc-20261025-ENSG00000182459,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,30.0,3,0.1,47,30.0,0.0,0.0,0.0,8,0.1,39,300.0,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:TCGA|BRCA:validation|LUAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
VCX,ENSG00000182583,32.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000182583,https://v23.proteinatlas.org/ENSG00000182583-VCX/tissue/primary+data,,ihc-20261025-ENSG00000182583,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,32.5,3,0.4,47,32.5,0.0,0.0,0.2,8,0.4,39,81.25,False,5,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|GBM:validation|HNSC:TCGA|KICH:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.0037831021437578823,0.3114754098360656,0.3076923076923077,0.019966978886416225,0.22584933182759273,0.20588235294117652
CYLC1,ENSG00000183035,30.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000183035,https://v23.proteinatlas.org/ENSG00000183035-CYLC1/tissue/primary+data,,ihc-20261025-ENSG00000183035,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,30.3,3,0.0,47,30.3,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,31,20,GBM:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
RIMBP3C,ENSG00000183246,5.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000183246,https://v23.proteinatlas.org/ENSG00000183246-RIMBP3C/tissue/primary+data,,ihc-20261025-ENSG00000183246,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.0,3,0.2,47,5.0,0.0,0.0,0.0,8,0.2,39,25.0,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005901766647252961,0.005901766647252961,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
SPDYE4,ENSG00000183318,7.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000183318,https://v23.proteinatlas.org/ENSG00000183318-SPDYE4/tissue/primary+data,,ihc-20261025-ENSG00000183318,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.6,3,0.8,47,7.6,0.0,0.1,0.1,8,0.8,39,9.499999999999998,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,COAD:validation|KIRC:TCGA|LUAD:TCGA|LUSC:TCGA|LUSC:validation|READ:validation|STAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005901766647252961,0.005901766647252961,0.0,0.012447626408493674,0.3201399341008014,0.3076923076923077,0.03237203972498091,0.23825439266615742,0.20588235294117652
PSG9,ENSG00000183668,103.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000183668,https://v23.proteinatlas.org/ENSG00000183668-PSG9/tissue/primary+data,,ihc-20261025-ENSG00000183668,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,103.4,3,0.7,47,0.0,0.0,103.4,0.2,8,0.7,39,147.71428571428572,False,0,0,Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_placenta_PC|Gong2021_reproductive_PC,True,False,31,20,BRCA:validation|COAD:validation|KICH:TCGA|KIRP:TCGA|LUSC:validation|READ:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005825242718446602,0.005825242718446602,0.0,0.014731434615094054,0.3224237423074018,0.3076923076923077,0.02620037914155561,0.2320827320827321,0.20588235294117652
NUTM1,ENSG00000184507,19.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000184507,https://v23.proteinatlas.org/ENSG00000184507-NUTM1/tissue/primary+data,,ihc-20261025-ENSG00000184507,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,19.2,3,0.2,47,19.2,0.0,0.0,0.0,8,0.2,39,95.99999999999999,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,20,COAD:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
ODF4,ENSG00000184650,12.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000184650,https://v23.proteinatlas.org/ENSG00000184650-ODF4/tissue/primary+data,,ihc-20261025-ENSG00000184650,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,12.7,3,0.0,47,12.7,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CIMIP4,ENSG00000185264,88.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000185264,https://v23.proteinatlas.org/ENSG00000185264-CIMIP4/tissue/primary+data,,ihc-20261025-ENSG00000185264,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,88.9,3,0.1,47,88.9,0.0,0.0,0.0,8,0.1,39,889.0,False,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,True,29,20,,carcinoid|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
TMEM210,ENSG00000185863,14.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000185863,https://v23.proteinatlas.org/ENSG00000185863-TMEM210/tissue/primary+data,,ihc-20261025-ENSG00000185863,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,14.4,3,1.4,47,14.4,0.0,0.0,0.5,8,1.4,39,10.285714285714286,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|daSilva2017_testis_biased,True,True,29,20,BRCA:TCGA|PRAD:TCGA,prostate cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.015814048600933845,0.32350635629324154,0.3076923076923077,0.0053475935828877,0.2112299465240642,0.20588235294117652
SPATA12,ENSG00000186451,19.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000186451,https://v23.proteinatlas.org/ENSG00000186451-SPATA12/tissue/primary+data,,ihc-20261025-ENSG00000186451,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,19.9,3,0.3,47,19.9,0.0,0.0,0.2,8,0.3,39,66.33333333333333,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|OV:TCGA|OV:validation|PAAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.011147850915169795,0.3188401586074775,0.3076923076923077,0.018146388990378758,0.22402874193155528,0.20588235294117652
SPATA31D3,ENSG00000186788,7.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,CTA,Pass,Affirmative reproductive admission and all applicable normal gates pass,All applicable gates pass,False,False,True,False,,,,,,True,False,oncoref.cta-research-selection.2026-10-26.1,CTA,Pass,Affirmative reproductive admission and all applicable normal gates pass,oncoref.target-sets.2026-10-25.2,False,,,Expression evidence,Unchanged,7.8,3,0.0,47,7.8,0.0,0.0,0.0,8,0.0,39,,True,0,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_testis_biased,False,False,29,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,False,False,False,False,False,False,Insufficient evidence,,"No qualifying reviewed, publication-consensus or expression route",oncoref.cta-membership.2026-10-26.2,Removed,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
DAZ3,ENSG00000187191,1.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000187191,https://v23.proteinatlas.org/ENSG00000187191-DAZ3/tissue/primary+data,,ihc-20261025-ENSG00000187191,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.4,3,0.6,47,1.4,0.0,0.0,0.0,8,0.6,39,2.3333333333333335,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.18632/oncotarget.21715,Jamin2021_CT|Jamin2021_core|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,PAAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005825242718446602,0.005825242718446602,0.0,0.006993006993006994,0.3146853146853147,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
H2AP,ENSG00000187516,42.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000187516,https://v23.proteinatlas.org/ENSG00000187516-H2AP/tissue/primary+data,,ihc-20261025-ENSG00000187516,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,42.9,3,0.2,47,42.9,0.0,0.0,0.0,8,0.2,39,214.49999999999997,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,20,GBM:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.0,0.3076923076923077,0.3076923076923077,0.006302521008403361,0.21218487394957988,0.20588235294117652
EZHIP,ENSG00000187690,5.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000187690,https://v23.proteinatlas.org/ENSG00000187690-EZHIP/tissue/primary+data,,ihc-20261025-ENSG00000187690,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.7,3,1.6,47,5.7,0.4,0.9,0.3,8,1.6,39,3.5625,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Jamin2021_core|Wang2016_CT,True,False,29,20,BLCA:TCGA|GBM:validation|HNSC:TCGA|LUSC:TCGA|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.011504007543611505,0.011504007543611505,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.062289546912309056,0.26817189985348555,0.20588235294117652
ZCCHC13,ENSG00000187969,22.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000187969,https://v23.proteinatlas.org/ENSG00000187969-ZCCHC13/tissue/primary+data,,ihc-20261025-ENSG00000187969,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,22.3,3,0.0,47,22.3,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,True,31,20,,lymphoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CIMIP2A,ENSG00000188163,59.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000188163,https://v23.proteinatlas.org/ENSG00000188163-CIMIP2A/tissue/primary+data,,ihc-20261025-ENSG00000188163,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,59.1,3,1.8,47,59.1,0.1,0.0,0.7,8,1.8,39,32.833333333333336,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|LIHC:validation|LUAD:validation|PRAD:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03059137558668824,0.03059137558668824,0.0,0.017137157307701992,0.3248294650000097,0.3076923076923077,0.13813516120145314,0.34401751414262965,0.20588235294117652
NANOS2,ENSG00000188425,3.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000188425,https://v23.proteinatlas.org/ENSG00000188425-NANOS2/tissue/primary+data,,ihc-20261025-ENSG00000188425,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.5,3,0.1,47,3.5,0.0,0.0,0.0,8,0.1,39,35.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,31,20,,cervical cancer|endometrial cancer|lymphoma|ovarian cancer|renal cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0017507002801120447,0.20763305322128855,0.20588235294117652
CATSPER4,ENSG00000188782,10.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000188782,https://v23.proteinatlas.org/ENSG00000188782-CATSPER4/tissue/primary+data,,ihc-20261025-ENSG00000188782,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.9,3,0.2,47,10.9,0.0,0.0,0.0,8,0.2,39,54.5,False,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0053475935828877,0.2112299465240642,0.20588235294117652
FSCB,ENSG00000189139,31.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000189139,https://v23.proteinatlas.org/ENSG00000189139-FSCB/tissue/primary+data,,ihc-20261025-ENSG00000189139,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,31.6,3,0.0,47,31.6,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,31,20,,glioma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
MAGEA1,ENSG00000198681,4.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000198681,https://v23.proteinatlas.org/ENSG00000198681-MAGEA1/tissue/primary+data,,ihc-20261025-ENSG00000198681,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,https://pubmed.ncbi.nlm.nih.gov/39038917/,Biological activity and manageable product safety do not establish repeated clinical responses; raw normal staining remains unresolved.,Not selected,Unchanged,4.4,3,0.0,47,4.4,0.0,0.0,0.0,8,0.0,39,,True,6,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1186/s12967-024-04918-0|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Jamin2021_core|Loriot2025_S1|Seager2024_CTA|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,head and neck cancer|lung cancer|skin cancer|testis cancer,False,1,3,0.05,2,,Context only,"User excluded non-MAGEA4 MAGE genes from positive controls and automatic reviewed admission; retain citations and concerns, and evaluate ordinary publication/expression routes.",https://pubmed.ncbi.nlm.nih.gov/1840703/,Original normal panel is incomplete; current reproductive RNA is below the former 5 nTPM admission floor.,Locus,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
SYCP1,ENSG00000198765,39.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000198765,https://v23.proteinatlas.org/ENSG00000198765-SYCP1/tissue/primary+data,,ihc-20261025-ENSG00000198765,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,39.0,3,0.5,47,39.0,0.0,0.0,0.5,8,0.1,39,78.0,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|PAAD:validation,,False,1,3,0.05,2,Cancer-germline,Membership support,Reviewed reproductive/developmental and tumor association supports biological membership; not a safety or approval claim.,https://pubmed.ncbi.nlm.nih.gov/9560255/,The study does not validate HLA presentation or a clinical targeting product.,Locus,True,True,True,True,True,False,Established,Cancer-germline,Reviewed reproductive/developmental and tumor association,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
MAGEB3,ENSG00000198798,17.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000198798,https://v23.proteinatlas.org/ENSG00000198798-MAGEB3/tissue/primary+data,,ihc-20261025-ENSG00000198798,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.9,3,17.3,47,4.9,0.0,0.0,17.3,8,0.0,39,0.2832369942196532,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,TGCT:TCGA,melanoma|testis cancer,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
FAM24A,ENSG00000203795,17.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000203795,https://v23.proteinatlas.org/ENSG00000203795-FAM24A/tissue/primary+data,,ihc-20261025-ENSG00000203795,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,17.1,3,0.0,47,17.1,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
OOEP,ENSG00000203907,13.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000203907,https://v23.proteinatlas.org/ENSG00000203907-OOEP/tissue/primary+data,,ihc-20261025-ENSG00000203907,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.8,3,1.7,47,13.8,0.5,1.4,0.3,8,1.7,39,8.11764705882353,False,4,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1371/journal.pgen.1011734,Bruggeman2018_GC|Chang2019_TGCT|Loriot2025_S2|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03204920641509956,0.03204920641509956,0.0,0.03164605804641602,0.3393383657387237,0.3076923076923077,0.059452531182842494,0.265334884124019,0.20588235294117652
C10orf62,ENSG00000203942,270.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000203942,https://v23.proteinatlas.org/ENSG00000203942-C10orf62/tissue/primary+data,,ihc-20261025-ENSG00000203942,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,270.2,3,0.8,47,270.2,0.0,0.0,0.3,8,0.8,39,337.74999999999994,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,GBM:validation|KIRP:TCGA|LIHC:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.0037424236260830655,0.3114347313183908,0.3076923076923077,0.08711674325485066,0.29299909619602715,0.20588235294117652
TSBP1,ENSG00000204296,33.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000204296,https://v23.proteinatlas.org/ENSG00000204296-TSBP1/tissue/primary+data,,ihc-20261025-ENSG00000204296,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,33.6,3,0.2,47,33.6,0.0,0.0,0.0,8,0.2,39,168.0,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,29,20,,prostate cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
SPATA31A1,ENSG00000204849,8.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,CTA,Pass,Affirmative reproductive admission and all applicable normal gates pass,All applicable gates pass,False,False,True,False,,,,,,True,False,oncoref.cta-research-selection.2026-10-26.1,CTA,Pass,Affirmative reproductive admission and all applicable normal gates pass,oncoref.target-sets.2026-10-25.2,False,,,Expression evidence,Unchanged,8.7,3,0.0,47,8.7,0.0,0.0,0.0,8,0.0,39,,True,0,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_testis_biased,False,False,29,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,False,False,False,False,False,False,Insufficient evidence,,"No qualifying reviewed, publication-consensus or expression route",oncoref.cta-membership.2026-10-26.2,Removed,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
MGAT4D,ENSG00000205301,22.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000205301,https://v23.proteinatlas.org/ENSG00000205301-MGAT4D/tissue/primary+data,,ihc-20261025-ENSG00000205301,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,22.0,3,0.5,47,22.0,0.0,0.0,0.5,8,0.1,39,44.0,False,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,False,29,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
SLCO6A1,ENSG00000205359,29.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000205359,https://v23.proteinatlas.org/ENSG00000205359-SLCO6A1/tissue/primary+data,,ihc-20261025-ENSG00000205359,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,29.4,3,0.0,47,29.4,0.0,0.2,0.0,8,0.0,39,,True,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,GBM:validation|LIHC:TCGA|LIHC:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
VCX3B,ENSG00000205642,14.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000205642,https://v23.proteinatlas.org/ENSG00000205642-VCX3B/tissue/primary+data,,ihc-20261025-ENSG00000205642,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,14.1,3,0.4,47,14.1,0.0,0.0,0.2,8,0.4,39,35.25,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:validation|KICH:TCGA|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUSC:TCGA|OV:validation|SKCM:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.0,0.3076923076923077,0.3076923076923077,0.018557422969187675,0.22443977591036418,0.20588235294117652
TTC23L,ENSG00000205838,21.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000205838,https://v23.proteinatlas.org/ENSG00000205838-TTC23L/tissue/primary+data,,ihc-20261025-ENSG00000205838,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,21.2,3,3.3,47,21.2,0.2,0.2,3.3,8,1.4,39,6.424242424242425,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.035784382337597016,0.035784382337597016,0.0,0.029737342400654686,0.3374296500929624,0.3076923076923077,0.1267580275760658,0.3326403805172423,0.20588235294117652
SMIM21,ENSG00000206026,2.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000206026,https://v23.proteinatlas.org/ENSG00000206026-SMIM21/tissue/primary+data,,ihc-20261025-ENSG00000206026,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.7,3,0.0,47,2.7,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,29,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TSSK1B,ENSG00000212122,52.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000212122,https://v23.proteinatlas.org/ENSG00000212122-TSSK1B/tissue/primary+data,,ihc-20261025-ENSG00000212122,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,52.1,3,0.2,47,52.1,0.0,0.0,0.1,8,0.2,39,260.5,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0014005602240896356,0.20728291316526615,0.20588235294117652
TTLL13,ENSG00000213471,7.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000213471,https://v23.proteinatlas.org/ENSG00000213471-TTLL13/tissue/primary+data,,ihc-20261025-ENSG00000213471,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.9,3,0.1,47,7.9,0.0,0.0,0.1,8,0.1,39,79.0,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,29,20,GBM:validation,colorectal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.0014005602240896356,0.20728291316526615,0.20588235294117652
MAGEB1,ENSG00000214107,15.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000214107,https://v23.proteinatlas.org/ENSG00000214107-MAGEB1/tissue/primary+data,,ihc-20261025-ENSG00000214107,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.0,3,0.5,47,15.0,0.0,0.0,0.5,8,0.0,39,30.0,False,6,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUSC:TCGA|SKCM:TCGA|TGCT:TCGA,testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
PSG3,ENSG00000221826,137.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000221826,https://v23.proteinatlas.org/ENSG00000221826-PSG3/tissue/primary+data,,ihc-20261025-ENSG00000221826,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,137.4,3,0.6,47,0.6,0.0,137.4,0.1,8,0.6,39,229.00000000000003,False,1,0,Cancer-germline|Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_placenta_PC|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005825242718446602,0.005825242718446602,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.016375781081663432,0.22225813402283995,0.20588235294117652
POM121L12,ENSG00000221900,12.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000221900,https://v23.proteinatlas.org/ENSG00000221900-POM121L12/tissue/primary+data,,ihc-20261025-ENSG00000221900,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,12.9,3,0.0,47,12.9,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,False,30,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CT47A12,ENSG00000226685,1.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000226685,https://v23.proteinatlas.org/ENSG00000226685-CT47A12/tissue/primary+data,,ihc-20261025-ENSG00000226685,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.1,3,0.0,47,1.1,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline,10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Loriot2025_S1|daSilva2017_testis_biased,True,False,29,20,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
RBMY1J,ENSG00000226941,1.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000226941,https://v23.proteinatlas.org/ENSG00000226941-RBMY1J/tissue/primary+data,,ihc-20261025-ENSG00000226941,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.4,3,0.0,47,1.4,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TSPY3,ENSG00000228927,2.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000228927,https://v23.proteinatlas.org/ENSG00000228927-TSPY3/tissue/primary+data,,ihc-20261025-ENSG00000228927,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.9,3,0.5,47,2.9,0.0,0.0,0.5,8,0.2,39,5.8,False,2,0,Cancer-germline,10.1038/ncomms10499|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Loriot2025_S1|Wang2016_CT|daSilva2017_testis_biased,True,True,31,20,LIHC:validation|TGCT:TCGA,testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TSPY8,ENSG00000229549,1.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000229549,https://v23.proteinatlas.org/ENSG00000229549-TSPY8/tissue/primary+data,,ihc-20261025-ENSG00000229549,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.2,3,0.0,47,1.2,0.0,0.0,0.0,8,0.0,39,,True,0,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_testis_biased,True,True,29,20,TGCT:TCGA,testis cancer,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CFAP97D1,ENSG00000231256,12.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000231256,https://v23.proteinatlas.org/ENSG00000231256-CFAP97D1/tissue/primary+data,,ihc-20261025-ENSG00000231256,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,12.9,3,0.5,47,12.9,0.0,0.1,0.1,8,0.5,39,25.8,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,True,29,20,BLCA:TCGA|CESC:TCGA|COAD:validation|KICH:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|TGCT:TCGA|UCEC:TCGA,colorectal cancer|lymphoma|stomach cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.011727009365699564,0.011727009365699564,0.0,0.00630517023959647,0.3139974779319042,0.3076923076923077,0.036929119473876504,0.24281147241505302,0.20588235294117652
PSG1,ENSG00000231924,252.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000231924,https://v23.proteinatlas.org/ENSG00000231924-PSG1/tissue/primary+data,,ihc-20261025-ENSG00000231924,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,252.6,3,0.6,47,0.0,0.0,252.6,0.1,8,0.6,39,421.0,False,0,0,Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_placenta_PC|Gong2021_reproductive_PC,True,False,31,20,COAD:validation|READ:validation|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.015281150756585093,0.015281150756585093,0.0,0.00728908188585608,0.3149813895781638,0.3076923076923077,0.023989160881744,0.2298715138229205,0.20588235294117652
TSPY4,ENSG00000233803,31.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000233803,https://v23.proteinatlas.org/ENSG00000233803-TSPY4/tissue/primary+data,,ihc-20261025-ENSG00000233803,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,31.8,3,0.2,47,31.8,0.0,0.0,0.0,8,0.2,39,159.0,False,2,0,Cancer-germline,10.1038/ncomms10499|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Loriot2025_S1|Wang2016_CT|daSilva2017_testis_biased,True,True,31,20,LIHC:TCGA|LIHC:validation|LUSC:TCGA|LUSC:validation|SKCM:TCGA|TGCT:TCGA,testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.007843137254901962,0.007843137254901962,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
RBMY1A1,ENSG00000234414,8.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000234414,https://v23.proteinatlas.org/ENSG00000234414-RBMY1A1/tissue/primary+data,,ihc-20261025-ENSG00000234414,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.3,3,0.0,47,8.3,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline,10.1038/ncomms10499|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Loriot2025_S1|Wang2016_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,LIHC:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CT47A1,ENSG00000236371,0.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000236371,https://v23.proteinatlas.org/ENSG00000236371-CT47A1/tissue/primary+data,,ihc-20261025-ENSG00000236371,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.5,3,0.0,47,0.5,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline,10.1038/ncomms10499|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Loriot2025_S1|Wang2016_CT|daSilva2017_testis_biased,True,False,31,20,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TSPY10,ENSG00000236424,1.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000236424,https://v23.proteinatlas.org/ENSG00000236424-TSPY10/tissue/primary+data,,ihc-20261025-ENSG00000236424,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.9,3,0.1,47,1.9,0.0,0.0,0.0,8,0.1,39,18.999999999999996,False,0,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_testis_biased,True,True,29,20,TGCT:TCGA,testis cancer,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CT47B1,ENSG00000236446,6.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000236446,https://v23.proteinatlas.org/ENSG00000236446-CT47B1/tissue/primary+data,,ihc-20261025-ENSG00000236446,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.7,3,0.0,47,6.7,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
STPG4,ENSG00000239605,14.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000239605,https://v23.proteinatlas.org/ENSG00000239605-STPG4/tissue/primary+data,,ihc-20261025-ENSG00000239605,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,14.3,3,0.2,47,14.3,0.1,0.0,0.1,8,0.2,39,71.5,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,29,20,COAD:validation|GBM:validation|READ:validation|STAD:TCGA,glioma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005940594059405941,0.005940594059405941,0.0,0.0037424236260830655,0.3114347313183908,0.3076923076923077,0.01295518207282913,0.21883753501400566,0.20588235294117652
LRRD1,ENSG00000240720,14.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000240720,https://v23.proteinatlas.org/ENSG00000240720-LRRD1/tissue/primary+data,,ihc-20261025-ENSG00000240720,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,14.3,3,0.4,47,14.3,0.1,0.0,0.3,8,0.4,39,35.75,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,False,30,20,CESC:TCGA|COAD:validation|GBM:validation|KICH:TCGA|KIRP:TCGA|OV:validation|PAAD:validation|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009785638758050563,0.009785638758050563,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.02798075752039946,0.23386311046157598,0.20588235294117652
RBMY1E,ENSG00000242389,2.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000242389,https://v23.proteinatlas.org/ENSG00000242389-RBMY1E/tissue/primary+data,,ihc-20261025-ENSG00000242389,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.5,3,0.0,47,2.5,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline,10.1038/ncomms10499|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Loriot2025_S1|Wang2016_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,LIHC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
RBMY1B,ENSG00000242875,0.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000242875,https://v23.proteinatlas.org/ENSG00000242875-RBMY1B/tissue/primary+data,,ihc-20261025-ENSG00000242875,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.2,3,0.0,47,0.2,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline,10.1038/ncomms10499|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Loriot2025_S1|Wang2016_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
PSG11,ENSG00000243130,51.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000243130,https://v23.proteinatlas.org/ENSG00000243130-PSG11/tissue/primary+data,,ihc-20261025-ENSG00000243130,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,51.3,3,0.5,47,0.0,0.0,51.3,0.0,8,0.5,39,102.6,False,1,0,Cancer-germline|Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_placenta_PC|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.011764705882352941,0.21764705882352947,0.20588235294117652
RBMY1D,ENSG00000244395,1.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000244395,https://v23.proteinatlas.org/ENSG00000244395-RBMY1D/tissue/primary+data,,ihc-20261025-ENSG00000244395,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.3,3,0.0,47,1.3,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_testis_biased|daSilva2017_tumor_proteomics,False,False,30,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
RAD21L1,ENSG00000244588,10.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000244588,https://v23.proteinatlas.org/ENSG00000244588-RAD21L1/tissue/primary+data,,ihc-20261025-ENSG00000244588,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.4,3,0.8,47,10.4,0.0,0.0,0.2,8,0.8,39,13.0,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|GBM:validation|TGCT:TCGA,colorectal cancer|melanoma|ovarian cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.008403361344537816,0.21428571428571433,0.20588235294117652
SPATS1,ENSG00000249481,21.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000249481,https://v23.proteinatlas.org/ENSG00000249481-SPATS1/tissue/primary+data,,ihc-20261025-ENSG00000249481,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,21.4,3,7.4,47,21.4,0.0,0.0,7.4,8,1.0,39,2.8918918918918917,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|CESC:TCGA|KICH:TCGA|LUAD:TCGA|OV:TCGA|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,ovarian cancer|pancreatic cancer|prostate cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.0037831021437578823,0.3114754098360656,0.3076923076923077,0.04379566511919453,0.24967801806037104,0.20588235294117652
KIAA1210,ENSG00000250423,40.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000250423,https://v23.proteinatlas.org/ENSG00000250423-KIAA1210/tissue/primary+data,,ihc-20261025-ENSG00000250423,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,31.8,3,40.8,47,31.8,0.2,0.0,40.8,8,1.3,39,0.7794117647058825,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:validation|KICH:TCGA|OV:TCGA|PRAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.04179537427619269,0.2476777272173692,0.20588235294117652
RNASE12,ENSG00000258436,679.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000258436,https://v23.proteinatlas.org/ENSG00000258436-RNASE12/tissue/primary+data,,ihc-20261025-ENSG00000258436,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.3,3,679.2,47,1.3,0.0,0.1,679.2,8,0.2,39,0.0019140164899882214,False,1,0,Cancer-germline|Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_placenta_PC|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,False,True,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0053475935828877,0.2112299465240642,0.20588235294117652
TSPY1,ENSG00000258992,7.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000258992,https://v23.proteinatlas.org/ENSG00000258992-TSPY1/tissue/primary+data,,ihc-20261025-ENSG00000258992,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.1,3,0.0,47,7.1,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_testis_biased,True,True,31,20,LIHC:TCGA|LIHC:validation|LUSC:TCGA|TGCT:TCGA,testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
HSFX2,ENSG00000268738,12.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000268738,https://v23.proteinatlas.org/ENSG00000268738-HSFX2/tissue/primary+data,,ihc-20261025-ENSG00000268738,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,12.0,3,2.0,47,12.0,1.0,0.4,1.3,8,2.0,39,6.0,False,1,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_CT|daSilva2017_testis_biased,True,False,28,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0645125014057053,0.0645125014057053,0.0,0.06842484849434244,0.37611715618665015,0.3076923076923077,0.16936160509530074,0.37524395803647725,0.20588235294117652
CALR3,ENSG00000269058,63.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000269058,https://v23.proteinatlas.org/ENSG00000269058-CALR3/tissue/primary+data,,ihc-20261025-ENSG00000269058,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,63.0,3,0.8,47,63.0,0.0,0.0,0.8,8,0.1,39,78.75,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.0,0.3076923076923077,0.3076923076923077,0.005602240896358543,0.21148459383753507,0.20588235294117652
CT45A10,ENSG00000269586,9.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000269586,https://v23.proteinatlas.org/ENSG00000269586-CT45A10/tissue/primary+data,,ihc-20261025-ENSG00000269586,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.0,3,1.4,47,9.0,0.0,0.0,0.0,8,1.4,39,6.428571428571429,False,1,0,Cancer-germline,10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Loriot2025_S1|daSilva2017_testis_biased,True,True,26,20,BLCA:TCGA|GBM:TCGA|HNSC:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,ovarian cancer|stomach cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.03657973185787395,0.24246208479905046,0.20588235294117652
CT45A2,ENSG00000271449,0.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000271449,https://v23.proteinatlas.org/ENSG00000271449-CT45A2/tissue/primary+data,,ihc-20261025-ENSG00000271449,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.2,3,0.0,47,0.2,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline,10.1002/1878-0261.12900|10.18632/oncotarget.21715,Jamin2021_CT|Jamin2021_core|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,False,True,28,20,,ovarian cancer|stomach cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
LYZL6,ENSG00000275722,46.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000275722,https://v23.proteinatlas.org/ENSG00000275722-LYZL6/tissue/primary+data,,ihc-20261025-ENSG00000275722,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,46.6,3,1.1,47,46.6,0.0,0.0,0.0,8,1.1,39,42.36363636363636,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,True,28,20,LUAD:validation,ovarian cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.025721586467072788,0.025721586467072788,0.0,0.0037424236260830655,0.3114347313183908,0.3076923076923077,0.009438558031908415,0.21532091097308492,0.20588235294117652
RIMBP3,ENSG00000275793,27.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,True,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,Material normal-expression or identity evidence remains unresolved,False,True,True,False,ihc-20261025-ENSG00000275793,https://v23.proteinatlas.org/ENSG00000275793-RIMBP3/tissue/primary+data,,ihc-20261025-ENSG00000275793,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Conflict,Material normal-expression or identity evidence remains unresolved,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,27.6,3,1.0,47,27.6,0.1,0.1,0.2,8,1.0,39,27.6,False,3,0,Cancer-germline|Cancer-reproductive,10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Bruggeman2018_GC|Carter2023_CT|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,False,28,20,BRCA:TCGA|BRCA:validation|COAD:validation|GBM:TCGA|HNSC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|OV:TCGA|PRAD:TCGA|READ:validation|STAD:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Unresolved normal evidence,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04115527663071097,0.04115527663071097,0.0,0.019184590295192757,0.32687689798750047,0.3076923076923077,0.02808317002690404,0.23396552296808054,0.20588235294117652
DAZL,ENSG00000092345,77.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,77.3,3,0.9,47,77.3,0.3,0.0,0.1,8,0.9,39,85.88888888888889,False,5,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Jamin2021_core|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,COAD:validation|READ:validation|STAD:TCGA|TGCT:TCGA,testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.012329465000009686,0.3200217726923174,0.3076923076923077,0.0053475935828877,0.2112299465240642,0.20588235294117652
TDRD1,ENSG00000095627,15.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.2,3,1.6,47,15.2,1.2,0.1,0.5,8,1.6,39,9.499999999999998,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935,Bruggeman2018_GC|Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,20,BRCA:TCGA|BRCA:validation|COAD:validation|GBM:validation|HNSC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.023268713425964448,0.023268713425964448,0.0,0.0172959972338608,0.3249883049261685,0.3076923076923077,0.0838928193148142,0.2897751722559907,0.20588235294117652
LRRC74A,ENSG00000100565,6.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.4,3,0.3,47,6.4,0.1,0.0,0.0,8,0.3,39,21.333333333333336,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,29,20,COAD:validation|READ:validation,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|liver cancer|lung cancer|lymphoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005825242718446602,0.005825242718446602,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
SALL4,ENSG00000101115,3.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,False,True,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.8,3,5.6,47,3.8,0.2,0.2,2.4,8,5.6,39,0.6785714285714286,False,0,0,,,,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,testis cancer,False,1,3,0.05,2,Oncofetal,Membership support,Reviewed reproductive/developmental and tumor association supports biological membership; not a safety or approval claim.,https://pubmed.ncbi.nlm.nih.gov/23758232/,Adult liver negativity is not whole-body absence; a tumor regulator is not automatically a validated HLA antigen.,Locus,True,True,False,False,False,False,Established,Oncofetal,Reviewed reproductive/developmental and tumor association,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0891618185735833,0.0891618185735833,0.0,0.04216317216430431,0.34985547985661203,0.3076923076923077,0.14876138769844716,0.3546437406396237,0.20588235294117652
OVOL3,ENSG00000105261,3.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.7,3,0.8,47,3.7,0.0,0.0,0.1,8,0.8,39,4.625,False,1,0,Cancer-germline,10.1002/cam4.2223,Chang2019_TGCT,True,False,29,0,BLCA:TCGA|COAD:validation|HNSC:TCGA|LUAD:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.016795012834616797,0.016795012834616797,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.018845285149632976,0.22472763809080948,0.20588235294117652
NOBOX,ENSG00000106410,0.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.5,3,0.0,47,0.3,0.5,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,HNSC:TCGA|LUSC:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
SLC26A8,ENSG00000112053,42.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,42.8,3,4.9,47,42.8,0.0,0.1,0.1,8,4.9,39,8.734693877551019,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|GBM:validation|PAAD:validation|READ:validation|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.024083584829071147,0.024083584829071147,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.088729606460198,0.2946119594013745,0.20588235294117652
PRDM13,ENSG00000112238,0.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,True,True,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.0,3,0.5,47,0.0,0.0,0.0,0.0,8,0.5,39,0.0,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|HNSC:TCGA|LUSC:TCGA|SKCM:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern|Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0058823529411764705,0.211764705882353,0.20588235294117652
PCDHB6,ENSG00000113211,1.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.8,3,1.9,47,1.8,1.2,0.4,1.9,8,1.8,39,0.9473684210526316,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT|Jamin2021_core,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|colorectal cancer|endometrial cancer|ovarian cancer|pancreatic cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04149300130390818,0.04149300130390818,0.0,0.05314743004300343,0.36083973773531114,0.3076923076923077,0.17356213614558166,0.3794444890867582,0.20588235294117652
PRAMEF1,ENSG00000116721,0.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.0,3,0.0,47,0.0,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
PRAMEF12,ENSG00000116726,0.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,False,False,False,False,False,False,Neither,Unassessed,The declared measurement panel or reference coverage is incomplete,The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Unassessed,The declared measurement panel or reference coverage is incomplete,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.0,3,0.1,47,0.0,0.0,0.0,0.0,8,0.1,39,0.0,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,TGCT:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0003501400560224089,0.20623249299719892,0.20588235294117652
SLC25A2,ENSG00000120329,6.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.4,3,0.2,47,6.4,0.1,0.0,0.2,8,0.2,39,32.0,False,4,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|COAD:validation|GBM:validation|PAAD:validation|READ:validation,endometrial cancer|liver cancer|pancreatic cancer|prostate cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.00788196466705494,0.00788196466705494,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.021899668958492484,0.227782021899669,0.20588235294117652
TTLL2,ENSG00000120440,17.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,17.9,3,1.6,47,17.9,0.1,0.0,0.3,8,1.6,39,11.187499999999998,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:validation|COAD:TCGA|COAD:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:validation|READ:TCGA|READ:validation|STAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005825242718446602,0.005825242718446602,0.0,0.007329760403530896,0.3150220680958386,0.3076923076923077,0.05211920077648978,0.2580015537176663,0.20588235294117652
RGSL1,ENSG00000121446,4.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.8,3,1.1,47,4.8,0.0,0.0,1.1,8,0.2,39,4.363636363636363,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,LIHC:TCGA|LIHC:validation|PAAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
H2BW1,ENSG00000123569,0.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.5,3,0.0,47,0.5,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,29,20,BLCA:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|lymphoma|melanoma|prostate cancer|renal cancer|skin cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
MAGEA9,ENSG00000123584,3.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.6,3,0.0,47,3.6,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Gong2021_reproductive_PC|Jamin2021_CT|Loriot2025_S1|Wang2016_CT|daSilva2017_testis_biased,True,False,30,0,BLCA:TCGA|HNSC:TCGA|LUSC:TCGA|LUSC:validation|STAD:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
ATXN3L,ENSG00000123594,3.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.9,3,0.0,47,3.9,0.0,0.1,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,True,31,20,,breast cancer|carcinoid|cervical cancer|colorectal cancer|glioma|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
GTSF1L,ENSG00000124196,217.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,217.5,3,1.4,47,217.5,0.0,0.0,0.2,8,1.4,39,155.35714285714286,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|KIRC:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.022756617861642382,0.022756617861642382,0.0,0.014553014553014552,0.32224532224532226,0.3076923076923077,0.007672634271099744,0.21355498721227625,0.20588235294117652
ANKRD60,ENSG00000124227,3.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.5,3,0.2,47,3.5,0.0,0.0,0.0,8,0.2,39,17.5,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,False,True,29,20,,liver cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.0,0.3076923076923077,0.3076923076923077,0.009549274255156608,0.21543162719633313,0.20588235294117652
DNAH8,ENSG00000124721,7.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,True,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.6,3,2.5,47,7.6,0.0,0.3,2.5,8,1.6,39,3.04,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,PRAD:TCGA|TGCT:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern|Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04240102171136654,0.04240102171136654,0.0,0.007178193811232904,0.3148705015035406,0.3076923076923077,0.005602240896358543,0.21148459383753507,0.20588235294117652
BHLHE23,ENSG00000125533,0.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.2,3,0.2,47,0.2,0.0,0.0,0.0,8,0.2,39,1.0,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,TGCT:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0014005602240896356,0.20728291316526615,0.20588235294117652
CSTL1,ENSG00000125823,1.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.7,3,0.1,47,1.7,0.0,0.0,0.0,8,0.1,39,17.0,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|PAAD:validation|READ:validation|STAD:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TSKS,ENSG00000126467,116.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,116.7,3,1.7,47,116.7,0.3,0.8,0.9,8,1.7,39,68.64705882352942,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|HNSC:TCGA|LUAD:TCGA|LUSC:TCGA|LUSC:validation|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.07548131143993589,0.07548131143993589,0.0,0.02712992360608069,0.3348222312983884,0.3076923076923077,0.08382940714067538,0.2897117600818519,0.20588235294117652
CTAG2,ENSG00000126890,10.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,True,False,True,False,False,True,Neither,Variable,Reviewed vital-tissue donor variability with negative local IHC requires reconsideration,Reviewed vital-tissue donor variability with negative local IHC requires reconsideration; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Variable,Reviewed vital-tissue donor variability with negative local IHC requires reconsideration,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.1,3,5.1,47,10.1,0.4,2.5,1.5,8,5.1,39,1.9803921568627452,False,2,0,Cancer-germline,10.1186/s12967-024-04918-0|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Loriot2025_S1|Seager2024_CTA|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|COAD:validation|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,colorectal cancer|lung cancer|melanoma|ovarian cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,Cancer-germline,Membership support,Reviewed reproductive/developmental and tumor association supports biological membership; not a safety or approval claim.,https://pubmed.ncbi.nlm.nih.gov/9626360/,RNA discovery does not establish protein selectivity; existing donor variability is retained.,Locus,True,True,True,False,False,False,Established,Cancer-germline,Reviewed reproductive/developmental and tumor association,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Variable,Not imported; oncofetal admission uses cited gene-specific evidence,Limited imported donors; see separate donor summaries and intervals,0.06815129643294149,0.06815129643294149,0.0,0.019890971229892678,0.3275832789222004,0.3076923076923077,0.20977244213409738,0.4156547950752739,0.20588235294117652
CCDC62,ENSG00000130783,68.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,68.0,3,1.4,47,68.0,0.1,0.0,0.3,8,1.4,39,48.57142857142858,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:validation|KIRP:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02517238751696007,0.02517238751696007,0.0,0.017332922674012045,0.32502523036631975,0.3076923076923077,0.09143194653387221,0.2973142994750487,0.20588235294117652
C3orf20,ENSG00000131379,6.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.4,3,0.4,47,6.4,0.0,0.1,0.1,8,0.4,39,16.0,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,GBM:validation,colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0037424236260830655,0.3114347313183908,0.3076923076923077,0.021328096455973694,0.2272104493971502,0.20588235294117652
USP29,ENSG00000131864,4.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.8,3,1.6,47,4.8,0.1,0.2,0.2,8,1.6,39,2.9999999999999996,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|KICH:TCGA|KIRC:TCGA|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02602495543672015,0.02602495543672015,0.0,0.01847385824117712,0.32616616593348485,0.3076923076923077,0.0767936950801401,0.28267604802131663,0.20588235294117652
FTHL17,ENSG00000132446,3.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.8,3,0.1,47,3.8,0.0,0.0,0.0,8,0.1,39,37.99999999999999,False,5,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|LUSC:TCGA|LUSC:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
VRTN,ENSG00000133980,1.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.6,3,1.4,47,1.6,0.4,0.0,1.4,8,0.4,39,1.142857142857143,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,30,20,COAD:validation|READ:validation|STAD:TCGA|TGCT:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.00859079445145019,0.3162831021437579,0.3076923076923077,0.008148714031066972,0.2140310669722435,0.20588235294117652
ADAM30,ENSG00000134249,25.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,25.2,3,0.0,47,25.2,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,31,20,,colorectal cancer|ovarian cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
FAM186B,ENSG00000135436,44.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,44.7,3,1.5,47,44.7,0.6,0.1,0.4,8,1.5,39,29.8,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,True,31,20,BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer|endometrial cancer|liver cancer|prostate cancer|renal cancer|stomach cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04972864736733757,0.04972864736733757,0.0,0.039046968310010643,0.34673927600231835,0.3076923076923077,0.1325977328534873,0.3384800857946638,0.20588235294117652
SPDYE1,ENSG00000136206,6.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.7,3,1.5,47,6.7,0.2,0.2,0.3,8,1.5,39,4.466666666666667,False,1,0,Cancer-germline,10.1038/s41388-018-0357-2,Bruggeman2018_GC,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|COAD:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04069919229827854,0.04069919229827854,0.0,0.024089485783034173,0.33178179347534187,0.3076923076923077,0.11439189540212558,0.3202742483433021,0.20588235294117652
CAPN11,ENSG00000137225,29.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,29.5,3,2.2,47,29.5,0.0,0.5,2.2,8,2.1,39,13.409090909090908,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|COAD:validation|KIRC:TCGA|KIRC:validation|LIHC:validation|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA,ovarian cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.08168725321117332,0.08168725321117332,0.0,0.024389313753406826,0.3320816214457145,0.3076923076923077,0.06315530164635025,0.26903765458752676,0.20588235294117652
MMP20,ENSG00000137674,0.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.6,3,0.1,47,0.6,0.0,0.0,0.1,8,0.1,39,5.999999999999999,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
BRDT,ENSG00000137948,127.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,127.6,3,2.6,47,127.6,0.4,0.9,0.3,8,2.6,39,49.07692307692307,False,5,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.019457013574660637,0.019457013574660637,0.0,0.011072184029613961,0.3187644917219217,0.3076923076923077,0.051853943158290984,0.2577362960994675,0.20588235294117652
SULT6B1,ENSG00000138068,1.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.8,3,0.3,47,1.8,0.0,0.0,0.1,8,0.3,39,6.0,False,0,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,31,0,KIRC:TCGA|STAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.007672634271099744,0.21355498721227625,0.20588235294117652
C4orf17,ENSG00000138813,19.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,19.5,3,0.0,47,19.5,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TTLL8,ENSG00000138892,4.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.0,3,0.0,47,4.0,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,False,True,30,20,,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
SYCP3,ENSG00000139351,80.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,80.5,3,0.7,47,80.5,0.5,0.0,0.1,8,0.7,39,115.00000000000001,False,5,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|COAD:validation|GBM:validation|LIHC:validation|PAAD:validation|READ:validation|TGCT:TCGA,renal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005901766647252961,0.005901766647252961,0.0,0.009700261907071493,0.3173925695993792,0.3076923076923077,0.02714823303058597,0.2330305859717625,0.20588235294117652
FOXN4,ENSG00000139445,11.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,True,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11.1,3,1.8,47,11.1,0.0,0.0,1.8,8,0.8,39,6.166666666666666,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|LIHC:TCGA|LIHC:validation|LUAD:TCGA|OV:TCGA|OV:validation|PRAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|liver cancer|ovarian cancer|pancreatic cancer|renal cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern|Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.007805440738248582,0.007805440738248582,0.0,0.003663003663003663,0.31135531135531136,0.3076923076923077,0.04689330277565572,0.25277565571683225,0.20588235294117652
ADAM21,ENSG00000139985,8.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.4,3,1.3,47,8.4,0.2,0.0,0.2,8,1.3,39,6.461538461538462,False,0,0,,,,True,True,31,20,BRCA:validation|GBM:validation|OV:TCGA|PRAD:TCGA|UCEC:TCGA,renal cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005940594059405941,0.005940594059405941,0.0,0.008827238335435058,0.3165195460277428,0.3076923076923077,0.056360785420887724,0.26224313836206425,0.20588235294117652
ABCC12,ENSG00000140798,2.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.8,3,1.4,47,2.8,0.1,0.0,0.4,8,1.4,39,2.0,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BRCA:validation|TGCT:TCGA,breast cancer|cervical cancer|colorectal cancer|glioma|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.03036856453811471,0.23625091747929122,0.20588235294117652
DPEP3,ENSG00000141096,45.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,45.7,3,2.0,47,45.7,0.1,0.1,0.2,8,2.0,39,22.85,False,5,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,BRCA:validation|GBM:TCGA|KIRC:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|SKCM:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04300583904544301,0.04300583904544301,0.0,0.021687516167949804,0.3293798238602575,0.3076923076923077,0.07136887443792815,0.2772512273791047,0.20588235294117652
SLC25A52,ENSG00000141437,10.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.1,3,0.6,47,10.1,0.0,0.0,0.1,8,0.6,39,16.833333333333332,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,29,20,GBM:validation|TGCT:TCGA,breast cancer|endometrial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009823335274703943,0.009823335274703943,0.0,0.0,0.3076923076923077,0.3076923076923077,0.03768976121917298,0.2435721141603495,0.20588235294117652
ZIM3,ENSG00000141946,0.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.3,3,0.2,47,0.3,0.0,0.0,0.0,8,0.2,39,1.4999999999999998,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|CESC:TCGA|KICH:TCGA|KIRP:TCGA|PAAD:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|colorectal cancer|endometrial cancer|liver cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|stomach cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.0,0.3076923076923077,0.3076923076923077,0.006748153806977336,0.21263050674815384,0.20588235294117652
CIB3,ENSG00000141977,0.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,True,True,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.7,3,1.2,47,0.7,0.0,0.0,0.1,8,1.2,39,0.5833333333333334,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:TCGA|BRCA:validation,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern|Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.022058823529411763,0.22794117647058829,0.20588235294117652
DMRTC2,ENSG00000142025,39.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,39.7,3,0.3,47,39.7,0.0,0.0,0.1,8,0.3,39,132.33333333333334,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:TCGA|BRCA:validation|LUAD:TCGA,colorectal cancer|endometrial cancer|liver cancer|melanoma|prostate cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.007525525769840948,0.31521783346214866,0.3076923076923077,0.014660211910851297,0.2205425648520278,0.20588235294117652
ACP4,ENSG00000142513,3.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.6,3,1.2,47,3.6,0.0,0.0,0.0,8,1.2,39,3.0,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,0,COAD:validation|LIHC:TCGA|PRAD:TCGA|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.021428571428571432,0.021428571428571432,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.021540948395168343,0.22742330133634486,0.20588235294117652
HORMAD1,ENSG00000143452,114.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,114.3,3,6.6,47,114.3,0.0,0.5,0.2,8,6.6,39,17.31818181818182,False,6,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Jamin2021_core|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|HNSC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,colorectal cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09995340238449751,0.09995340238449751,0.0,0.046505581520819905,0.3541978892131276,0.3076923076923077,0.02946269416857652,0.23534504710975304,0.20588235294117652
TRIM43,ENSG00000144015,0.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.3,3,0.3,47,0.3,0.0,0.0,0.0,8,0.3,39,1.0,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,LUSC:validation|OV:TCGA|OV:validation|TGCT:TCGA|UCEC:TCGA,breast cancer|cervical cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005825242718446602,0.005825242718446602,0.0,0.0037424236260830655,0.3114347313183908,0.3076923076923077,0.0007002801120448178,0.20658263305322133,0.20588235294117652
ANKRD31,ENSG00000145700,4.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.8,3,0.6,47,4.8,0.1,0.0,0.3,8,0.6,39,8.0,False,0,0,,,,True,True,31,20,BRCA:validation|GBM:validation|PAAD:validation,liver cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.00788196466705494,0.00788196466705494,0.0,0.011955786149334537,0.3196480938416422,0.3076923076923077,0.015040798928266957,0.22092315186944347,0.20588235294117652
FAM217A,ENSG00000145975,14.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,True,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,14.5,3,1.5,47,14.5,0.0,0.0,0.5,8,1.5,39,9.666666666666666,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,29,20,,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|liver cancer|melanoma|ovarian cancer|pancreatic cancer|skin cancer|stomach cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern|Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.03568383875289245,0.24156619169406895,0.20588235294117652
H2BC1,ENSG00000146047,6.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,True,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.2,3,0.1,47,6.2,0.0,0.0,0.0,8,0.1,39,62.0,False,2,0,Cancer-germline,10.1002/cam4.2223|10.18632/oncotarget.21715,Chang2019_TGCT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,29,20,GBM:validation|TGCT:TCGA,liver cancer|lung cancer|melanoma|ovarian cancer|stomach cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.005602240896358543,0.21148459383753507,0.20588235294117652
PRDM14,ENSG00000147596,0.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.7,3,0.2,47,0.7,0.0,0.0,0.1,8,0.2,39,3.4999999999999996,False,2,0,Cancer-germline|Cancer-reproductive,10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,COAD:validation|READ:validation|TGCT:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|liver cancer|lung cancer|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.0,0.3076923076923077,0.3076923076923077,0.017093200916730326,0.22297555385790685,0.20588235294117652
TKTL2,ENSG00000151005,56.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,56.1,3,0.1,47,56.1,0.0,0.0,0.0,8,0.1,39,561.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,GBM:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0042016806722689065,0.2100840336134454,0.20588235294117652
POU4F2,ENSG00000151615,1.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.0,3,1.0,47,1.0,0.0,0.0,0.0,8,1.0,39,1.0,False,2,0,Cancer-germline|Cancer-reproductive,10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,GBM:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.010472370766488413,0.21635472370766493,0.20588235294117652
PANX3,ENSG00000154143,0.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.2,3,0.2,47,0.2,0.0,0.0,0.0,8,0.2,39,1.0,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.0010185892538833714,0.2069009421950599,0.20588235294117652
PSMA8,ENSG00000154611,16.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.4,3,1.7,47,16.4,0.1,0.2,0.1,8,1.7,39,9.647058823529411,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:validation|SKCM:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013445378151260505,0.013445378151260505,0.0,0.014959664184905599,0.3226519718772133,0.3076923076923077,0.005602240896358543,0.21148459383753507,0.20588235294117652
FBXO43,ENSG00000156509,3.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.5,3,0.3,47,3.5,0.1,0.0,0.1,8,0.3,39,11.666666666666668,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,31,20,BRCA:validation|GBM:validation|LIHC:validation|OV:validation|PAAD:validation,ovarian cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009785638758050563,0.009785638758050563,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
C9orf43,ENSG00000157653,44.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,44.3,3,1.9,47,44.3,0.8,0.2,1.2,8,1.9,39,23.31578947368421,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04381777977640422,0.04381777977640422,0.0,0.04356521232758103,0.35125752001988875,0.3076923076923077,0.19829993471861984,0.40418228765979636,0.20588235294117652
CIB4,ENSG00000157884,16.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.8,3,2.4,47,16.8,0.0,0.7,0.3,8,2.4,39,7.000000000000001,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|KIRC:TCGA|KIRC:validation|LUAD:validation|PRAD:TCGA|READ:validation|THCA:TCGA,breast cancer|colorectal cancer|endometrial cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03870967741935484,0.03870967741935484,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.03583526757968948,0.24171762052086598,0.20588235294117652
POM121L2,ENSG00000158553,7.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.3,3,0.0,47,7.3,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,31,20,,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
PAGE5,ENSG00000158639,25.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,25.8,3,1.0,47,25.8,0.0,0.0,0.3,8,1.0,39,25.8,False,5,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:validation|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005940594059405941,0.005940594059405941,0.0,0.00870713985468084,0.31639944754698857,0.3076923076923077,0.03183229813664596,0.23771465107782247,0.20588235294117652
TGM7,ENSG00000159495,0.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.8,3,1.6,47,0.8,0.0,0.0,0.3,8,1.6,39,0.5,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.004807692307692308,0.3125,0.3076923076923077,0.007672634271099744,0.21355498721227625,0.20588235294117652
IZUMO2,ENSG00000161652,62.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,62.8,3,0.1,47,62.8,0.0,0.0,0.1,8,0.1,39,627.9999999999999,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,30,20,COAD:TCGA|COAD:validation|LUAD:TCGA|LUAD:validation|PAAD:validation|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|liver cancer|lung cancer|lymphoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0003501400560224089,0.20623249299719892,0.20588235294117652
SYCE2,ENSG00000161860,25.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,25.9,3,3.2,47,25.9,1.2,0.4,1.0,8,3.2,39,8.093749999999998,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.08602032821896595,0.08602032821896595,0.0,0.055782384308415985,0.3634746920007237,0.3076923076923077,0.2128219811159483,0.4187043340571248,0.20588235294117652
AKNAD1,ENSG00000162641,4.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.7,3,0.3,47,4.7,0.0,0.0,0.0,8,0.3,39,15.666666666666668,False,2,0,Cancer-germline,10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Loriot2025_S2|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|GBM:TCGA|GBM:validation,breast cancer|colorectal cancer|endometrial cancer|liver cancer|ovarian cancer|renal cancer|testis cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005825242718446602,0.005825242718446602,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
DPPA2,ENSG00000163530,3.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.2,3,0.1,47,3.2,0.0,0.3,0.0,8,0.1,39,32.0,False,6,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BLCA:TCGA|HNSC:TCGA|KIRP:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
C4orf36,ENSG00000163633,10.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,True,True,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.4,3,1.4,47,10.4,0.5,0.0,1.0,8,1.4,39,7.42857142857143,False,0,0,,,,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:validation|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|READ:validation,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Antibody concern|Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0419262169131893,0.0419262169131893,0.0,0.019246805107460848,0.32693911279976856,0.3076923076923077,0.051757066462948816,0.2576394194041253,0.20588235294117652
ERICH6,ENSG00000163645,28.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,28.9,3,1.7,47,28.9,0.2,0.1,1.7,8,1.3,39,17.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PRAD:TCGA|READ:validation|SKCM:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03663953301421731,0.03663953301421731,0.0,0.02172444160810105,0.32941674930040876,0.3076923076923077,0.06447824341046847,0.270360596351645,0.20588235294117652
FANCD2OS,ENSG00000163705,59.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,59.9,3,1.0,47,59.9,0.0,0.0,0.0,8,1.0,39,59.9,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,0,COAD:validation|PAAD:validation|READ:validation|STAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009672505712109673,0.009672505712109673,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.0196078431372549,0.2254901960784314,0.20588235294117652
PLSCR2,ENSG00000163746,13.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.2,3,1.4,47,13.2,0.1,0.2,1.4,8,1.1,39,9.428571428571429,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,0,BRCA:validation|COAD:validation|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|READ:validation|STAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.015574272359362634,0.015574272359362634,0.0,0.017332922674012045,0.32502523036631975,0.3076923076923077,0.07192965162604631,0.2778120045672228,0.20588235294117652
PRDM9,ENSG00000164256,3.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.9,3,1.6,47,3.9,0.0,0.0,1.6,8,0.2,39,2.4375,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,COAD:validation|LUSC:validation|READ:validation|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
CDC20B,ENSG00000164287,2.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.5,3,2.0,47,2.5,0.0,0.0,2.0,8,1.1,39,1.25,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.18632/oncotarget.21715,Jamin2021_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:TCGA|BRCA:validation|KICH:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|OV:TCGA|OV:validation|PRAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.03163586612765724,0.23751821906883375,0.20588235294117652
CAGE1,ENSG00000164304,4.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.9,3,0.2,47,4.9,0.0,0.0,0.0,8,0.2,39,24.5,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|CESC:TCGA|LIHC:validation|TGCT:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0053475935828877,0.2112299465240642,0.20588235294117652
TBXT,ENSG00000164458,0.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; No source-backed cancer/reproductive candidate nomination,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.2,3,2.5,47,0.2,0.0,0.0,0.0,8,2.5,39,0.08,False,0,0,,,,True,False,29,20,LUAD:TCGA|LUAD:validation|TGCT:TCGA,,False,1,3,0.05,2,Oncofetal,Membership support,Reviewed reproductive/developmental and tumor association supports biological membership; not a safety or approval claim.,https://pubmed.ncbi.nlm.nih.gov/17438107/,Adult nucleus pulposus expression (PMID 28473691) contradicts an everywhere-else-absent premise; developmental atlas quantification remains unimported.,Locus,True,True,False,False,False,False,Established,Oncofetal,Reviewed reproductive/developmental and tumor association,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009785638758050563,0.009785638758050563,0.0,0.025105823967304045,0.33279813165961175,0.3076923076923077,0.023172905525846704,0.2290552584670232,0.20588235294117652
SPMIP7,ENSG00000164500,4.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.2,3,0.3,47,4.2,0.0,0.0,0.0,8,0.3,39,14.000000000000002,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,29,20,,colorectal cancer|liver cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.004110339788089148,0.20999269272926566,0.20588235294117652
SLC35G3,ENSG00000164729,2.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.3,3,0.1,47,2.3,0.0,0.0,0.0,8,0.1,39,22.999999999999996,False,0,0,Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_reproductive_PC,True,False,29,0,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
CXorf58,ENSG00000165182,3.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.8,3,0.4,47,3.8,0.0,0.0,0.4,8,0.4,39,9.499999999999998,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,GBM:validation,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.011765836777852543,0.011765836777852543,0.0,0.005003457674002359,0.31269576536631005,0.3076923076923077,0.04217734524639895,0.24805969818757545,0.20588235294117652
ERICH6B,ENSG00000165837,1.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.9,3,0.2,47,1.9,0.0,0.0,0.0,8,0.2,39,9.499999999999998,False,1,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_CT|daSilva2017_testis_biased,False,True,29,20,,breast cancer|carcinoid|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0006684491978609625,0.20655080213903748,0.20588235294117652
CCDC182,ENSG00000166329,27.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,27.7,3,0.1,47,27.7,0.0,0.0,0.0,8,0.1,39,277.0,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,True,True,29,20,GBM:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
POTED,ENSG00000166351,4.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.2,3,0.2,47,4.2,0.0,0.1,0.1,8,0.2,39,21.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005901766647252961,0.005901766647252961,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.013878278584160936,0.21976063152533745,0.20588235294117652
WDR88,ENSG00000166359,8.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,True,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.6,3,1.5,47,8.6,0.3,0.1,0.3,8,1.5,39,5.733333333333333,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1136/jitc-2023-007935,Carter2023_CT|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern|Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04304325176868312,0.04304325176868312,0.0,0.03525568648262951,0.3429479941749372,0.3076923076923077,0.12465784020815328,0.3305401931493298,0.20588235294117652
MS4A5,ENSG00000166930,43.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,43.3,3,0.2,47,43.3,0.0,0.0,0.0,8,0.2,39,216.49999999999997,False,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,True,31,20,,colorectal cancer|liver cancer|prostate cancer|stomach cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
MAJIN,ENSG00000168070,21.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,21.8,3,2.8,47,21.8,0.0,0.0,2.0,8,2.8,39,7.7857142857142865,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT,True,False,29,0,BRCA:TCGA|CESC:TCGA|COAD:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.051243285633244456,0.051243285633244456,0.0,0.02455992990101927,0.332252237593327,0.3076923076923077,0.07926806129821558,0.2851504142393921,0.20588235294117652
TRIM49,ENSG00000168930,0.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.3,3,0.0,47,0.3,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
GOT1L1,ENSG00000169154,13.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.7,3,0.4,47,13.7,0.3,0.1,0.4,8,0.2,39,34.24999999999999,False,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,True,31,20,,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
OR6F1,ENSG00000169214,1.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.3,3,0.0,47,1.3,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
HTRA4,ENSG00000169495,64.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,64.5,3,6.8,47,0.8,0.6,64.5,1.1,8,6.8,39,9.48529411764706,False,0,0,Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_placenta_PC|Gong2021_reproductive_PC,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,prostate cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.054206491099694984,0.054206491099694984,0.0,0.04935845363417715,0.35705076132648483,0.3076923076923077,0.17321880862966357,0.37910116157084006,0.20588235294117652
TAS2R1,ENSG00000169777,7.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.3,3,0.2,47,7.3,0.0,0.0,0.1,8,0.2,39,36.5,False,1,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_CT|daSilva2017_testis_biased,False,True,31,20,,glioma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.0036923860453272213,0.20957473898650375,0.20588235294117652
USP50,ENSG00000170236,1.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.5,3,0.6,47,1.5,0.1,0.0,0.3,8,0.6,39,2.5,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,GBM:validation|LIHC:validation|PAAD:validation|PRAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|colorectal cancer|endometrial cancer|liver cancer|melanoma|pancreatic cancer|renal cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013707207385501543,0.013707207385501543,0.0,0.005044136191677176,0.31273644388398486,0.3076923076923077,0.05667510239121492,0.26255745533239144,0.20588235294117652
C7orf33,ENSG00000170279,0.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.2,3,1.3,47,0.2,0.0,0.0,0.0,8,1.3,39,0.15384615384615385,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.011586452762923352,0.21746880570409988,0.20588235294117652
DYDC1,ENSG00000170788,123.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,123.0,3,5.4,47,123.0,0.0,0.0,5.4,8,1.5,39,22.777777777777775,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|KICH:TCGA|KIRC:TCGA|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|PRAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|renal cancer|skin cancer|stomach cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.025258379213754466,0.23114073215493097,0.20588235294117652
C8orf74,ENSG00000171060,16.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.6,3,0.0,47,16.6,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
XAGE5,ENSG00000171405,1.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.1,3,0.0,47,1.1,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_testis_biased,True,False,31,20,LIHC:TCGA|LIHC:validation|LUSC:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
SLFNL1,ENSG00000171790,73.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,73.9,3,4.0,47,73.9,1.3,0.1,1.4,8,4.0,39,18.475,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.034407103298535587,0.034407103298535587,0.0,0.0635708495804013,0.371263157272709,0.3076923076923077,0.18531335981835115,0.3911957127595277,0.20588235294117652
CDY1,ENSG00000172288,1.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,True,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.3,3,0.0,47,1.3,0.0,0.0,0.0,8,0.0,39,,True,0,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_testis_biased,False,True,30,20,,liver cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CDY1B,ENSG00000172352,1.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,True,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.8,3,0.0,47,1.8,0.0,0.0,0.0,8,0.0,39,,True,0,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_testis_biased,False,True,30,20,,liver cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
DNAJB7,ENSG00000172404,10.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,False,True,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.1,3,0.7,47,10.1,0.3,0.0,0.2,8,0.7,39,14.428571428571429,False,0,0,,,,True,True,31,20,BRCA:validation|COAD:validation|LIHC:validation|PRAD:TCGA|READ:validation|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|colorectal cancer|glioma|liver cancer|lung cancer|melanoma|pancreatic cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.011765836777852543,0.011765836777852543,0.0,0.010047593865679535,0.31773990155798726,0.3076923076923077,0.06530710219968532,0.27118945514086185,0.20588235294117652
EFCAB3,ENSG00000172421,5.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.8,3,0.4,47,5.8,0.0,0.0,0.0,8,0.4,39,14.499999999999998,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|CESC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|TGCT:TCGA|UCEC:TCGA,glioma|head and neck cancer|ovarian cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.007692307692307693,0.007692307692307693,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.00267379679144385,0.20855614973262038,0.20588235294117652
HSFY1,ENSG00000172468,10.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.3,3,0.7,47,10.3,0.0,0.0,0.3,8,0.7,39,14.714285714285717,False,0,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_testis_biased,True,False,30,0,BLCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.027478997747539945,0.23336135068871647,0.20588235294117652
FAM170B,ENSG00000172538,6.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.3,3,0.0,47,6.3,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,31,20,,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
XKR3,ENSG00000172967,7.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.9,3,0.1,47,7.9,0.0,0.0,0.0,8,0.1,39,79.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,GBM:validation|KIRP:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0003501400560224089,0.20623249299719892,0.20588235294117652
CST9,ENSG00000173335,1.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.0,3,1.9,47,0.0,0.0,0.0,1.9,8,0.1,39,0.0,False,1,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:TCGA|BRCA:validation|OV:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,False,True,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
RNASE11,ENSG00000173464,643.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,46.2,3,643.4,47,46.2,0.0,0.1,643.4,8,0.1,39,0.07180603046316444,False,2,0,Cancer-germline|Cancer-reproductive,10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,THCA:TCGA,breast cancer|carcinoid|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
SPMIP3,ENSG00000173728,34.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,34.0,3,0.5,47,34.0,0.0,0.0,0.0,8,0.5,39,68.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|daSilva2017_testis_biased,True,False,31,0,LIHC:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.00591715976331361,0.3136094674556213,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TOPAZ1,ENSG00000173769,3.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.4,3,0.0,47,3.4,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,False,True,29,20,,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TDRD12,ENSG00000173809,13.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.9,3,3.2,47,13.9,0.9,0.0,3.2,8,0.8,39,4.34375,False,5,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|GBM:validation|LUAD:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03046339280796536,0.03046339280796536,0.0,0.011267949395924013,0.3189602570882317,0.3076923076923077,0.04842951166480578,0.2543118646059823,0.20588235294117652
TENT5D,ENSG00000174016,3.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.3,3,0.0,47,3.3,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,29,20,,breast cancer|lung cancer|ovarian cancer|pancreatic cancer|stomach cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
ARL13A,ENSG00000174225,5.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,True,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.0,3,0.7,47,5.0,0.0,0.0,0.0,8,0.7,39,7.142857142857143,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,True,31,20,COAD:validation|READ:validation,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern|Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02088955288778129,0.02088955288778129,0.0,0.00870713985468084,0.31639944754698857,0.3076923076923077,0.02038839251115466,0.22627074545233117,0.20588235294117652
MYO1H,ENSG00000174527,0.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.9,3,0.3,47,0.9,0.1,0.0,0.0,8,0.3,39,3.0,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BRCA:validation|KICH:TCGA,carcinoid|glioma|liver cancer|lung cancer|lymphoma|melanoma|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.0,0.3076923076923077,0.3076923076923077,0.003632876075331318,0.20951522901650785,0.20588235294117652
HIGD2B,ENSG00000175202,3.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.5,3,0.3,47,3.5,0.0,0.0,0.3,8,0.2,39,11.666666666666668,False,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC,False,True,31,20,,liver cancer|renal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
UBQLNL,ENSG00000175518,30.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,30.9,3,1.5,47,30.9,2.3,0.2,1.5,8,1.4,39,20.599999999999998,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|OV:TCGA|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06941302864982737,0.06941302864982737,0.0,0.037791094897586405,0.34548340258989413,0.3076923076923077,0.1548054755767076,0.3606878285178841,0.20588235294117652
CCDC168,ENSG00000175820,8.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.6,3,0.1,47,8.6,0.0,0.0,0.1,8,0.1,39,85.99999999999999,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,False,False,29,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
TMPRSS7,ENSG00000176040,1.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.3,3,0.3,47,1.3,0.0,0.0,0.3,8,0.2,39,4.333333333333334,False,1,0,Cancer-germline,10.1038/ncomms10499,Wang2016_CT,True,True,31,20,BRCA:validation|GBM:TCGA|GBM:validation|KICH:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|skin cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.00788196466705494,0.00788196466705494,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.016965877259994905,0.22284823020117142,0.20588235294117652
HSF5,ENSG00000176160,47.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,47.3,3,1.1,47,47.3,0.0,0.0,0.0,8,1.1,39,42.99999999999999,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|GBM:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.020640057533261418,0.020640057533261418,0.0,0.01191765980498375,0.3196099674972915,0.3076923076923077,0.014355742296918769,0.2202380952380953,0.20588235294117652
ENTHD1,ENSG00000176177,10.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,True,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.7,3,1.3,47,10.7,0.0,0.0,0.0,8,1.3,39,8.23076923076923,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|GBM:validation|LUAD:validation|LUSC:TCGA|LUSC:validation|PAAD:TCGA|PAAD:validation|SKCM:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern|Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.026969245597126084,0.026969245597126084,0.0,0.008254041040926289,0.315946348733234,0.3076923076923077,0.002281947261663286,0.2081643002028398,0.20588235294117652
OR4N2,ENSG00000176294,3.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.7,3,0.5,47,3.7,0.0,0.0,0.0,8,0.5,39,7.4,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,30,0,GBM:TCGA|GBM:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.00591715976331361,0.3136094674556213,0.3076923076923077,0.004271708683473389,0.21015406162464992,0.20588235294117652
FOXR1,ENSG00000176302,4.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.1,3,0.1,47,4.1,1.0,0.0,0.0,8,0.1,39,40.99999999999999,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0014005602240896356,0.20728291316526615,0.20588235294117652
DCAF4L2,ENSG00000176566,20.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,20.7,3,0.0,47,20.7,0.0,0.0,0.0,8,0.0,39,,True,7,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Jamin2021_core|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BLCA:TCGA|GBM:validation|LIHC:TCGA|LIHC:validation|LUSC:TCGA|LUSC:validation|TGCT:TCGA,breast cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|testis cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TGIF2LY,ENSG00000176679,3.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.9,3,0.0,47,3.9,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_testis_biased,True,False,31,0,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
MAGEB6,ENSG00000176746,3.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,False,False,False,False,False,False,Neither,Unassessed,The declared measurement panel or reference coverage is incomplete,The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Unassessed,The declared measurement panel or reference coverage is incomplete,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.1,3,0.0,47,3.1,0.0,0.0,0.0,8,0.0,39,,True,5,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,LUSC:validation|SKCM:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TRIM60,ENSG00000176979,1.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.5,3,0.1,47,1.5,0.0,1.4,0.0,8,0.1,39,15.0,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_testis_biased,True,True,31,20,TGCT:TCGA,liver cancer|renal cancer,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline|Cancer-placental,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
RBM44,ENSG00000177483,15.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.3,3,0.5,47,15.3,0.0,0.1,0.3,8,0.5,39,30.6,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BRCA:validation|GBM:validation|LIHC:validation|PAAD:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.015610881476497165,0.015610881476497165,0.0,0.014930953058927676,0.3226232607512354,0.3076923076923077,0.05410258965246177,0.2599849425936383,0.20588235294117652
MAGEB10,ENSG00000177689,2.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.4,3,0.3,47,2.4,0.0,0.0,0.0,8,0.3,39,8.0,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,True,31,20,BLCA:TCGA|CESC:TCGA|COAD:validation|KICH:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,melanoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005901766647252961,0.005901766647252961,0.0,0.0037831021437578823,0.3114754098360656,0.3076923076923077,0.009423334551211788,0.2153056874923883,0.20588235294117652
SPATA31C2,ENSG00000177910,22.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,False,False,False,False,False,False,Neither,Unassessed,The declared measurement panel or reference coverage is incomplete,The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Unassessed,The declared measurement panel or reference coverage is incomplete,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.6,3,22.5,38,7.6,0.0,0.0,22.5,7,0.0,31,0.3377777777777778,False,2,0,Cancer-germline,10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Carter2023_CT|Loriot2025_S1|daSilva2017_testis_biased,False,False,0,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.36764705882352944,0.36764705882352944
TSSK6,ENSG00000178093,162.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,162.9,3,1.5,47,162.9,0.5,0.0,0.9,8,1.5,39,108.60000000000001,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUSC:TCGA|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.07402254389315689,0.07402254389315689,0.0,0.043755941225117084,0.35144824891742477,0.3076923076923077,0.16581683795393115,0.37169919089510767,0.20588235294117652
CEP295NL,ENSG00000178404,27.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,True,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,27.6,3,2.0,47,27.6,0.1,0.1,0.1,8,2.0,39,13.8,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|daSilva2017_testis_biased,True,True,29,20,COAD:validation|GBM:validation|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA,breast cancer|colorectal cancer|endometrial cancer|liver cancer|lung cancer|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern|Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.015497748430556275,0.015497748430556275,0.0,0.02265182859188637,0.33034413628419407,0.3076923076923077,0.03396358543417367,0.23984593837535018,0.20588235294117652
DEFB125,ENSG00000178591,1.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.1,3,1.5,47,0.1,0.0,0.0,1.5,8,0.0,39,0.06666666666666667,False,1,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_testis_biased,False,False,31,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,False,True,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
GDPD4,ENSG00000178795,3.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.6,3,1.4,47,3.6,0.0,0.2,0.0,8,1.4,39,2.5714285714285716,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT,True,False,31,0,LIHC:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.03383410130814975,0.23971645424932625,0.20588235294117652
TRIML2,ENSG00000179046,3.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.9,3,0.4,47,2.5,0.0,3.9,0.0,8,0.4,39,9.75,False,5,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|GBM:validation|HNSC:TCGA|PAAD:validation|SKCM:TCGA|TGCT:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline|Cancer-placental,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.005045199898141074,0.21092755283931758,0.20588235294117652
ZFP42,ENSG00000179059,2.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.0,3,0.7,47,2.0,0.0,0.7,0.3,8,0.7,39,2.857142857142857,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,True,31,20,BLCA:TCGA|CESC:TCGA|COAD:validation|HNSC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|lung cancer|lymphoma|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.021176513255721178,0.021176513255721178,0.0,0.012373896595208073,0.32006620428751575,0.3076923076923077,0.044522253345782754,0.25040460628695926,0.20588235294117652
PXT1,ENSG00000179165,2.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.2,3,0.3,47,2.2,0.0,0.0,0.2,8,0.3,39,7.333333333333334,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:validation|LUAD:validation|LUSC:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.01786129471551466,0.2237436476566912,0.20588235294117652
WDR97,ENSG00000179698,1.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,True,True,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; No source-backed cancer/reproductive candidate nomination,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.5,3,0.2,47,1.5,0.0,0.0,0.0,8,0.2,39,7.5,False,0,0,,,,True,False,29,20,BLCA:TCGA|CESC:TCGA|GBM:validation|OV:validation|PAAD:validation|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Antibody concern|Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.00897631779984721,0.21485867074102372,0.20588235294117652
NLRP8,ENSG00000179709,0.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.1,3,0.2,47,0.1,0.0,0.0,0.2,8,0.1,39,0.5,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|PRAD:TCGA,colorectal cancer|ovarian cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
NLRP11,ENSG00000179873,1.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.7,3,1.1,47,0.7,0.5,0.0,1.1,8,1.0,39,0.6363636363636362,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1136/jitc-2023-007935,Carter2023_CT|Chang2019_TGCT|Wang2016_CT,True,True,31,20,CESC:TCGA|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|SKCM:TCGA|TGCT:TCGA,cervical cancer|glioma|head and neck cancer|skin cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.009966236830329904,0.3176585445226376,0.3076923076923077,0.02775655716832187,0.2336389101094984,0.20588235294117652
GOLGA8J,ENSG00000179938,4.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; No source-backed cancer/reproductive candidate nomination,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.6,3,0.3,47,4.6,0.1,0.0,0.3,8,0.3,39,15.333333333333332,False,0,0,,,,True,False,29,0,PAAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.011765836777852543,0.011765836777852543,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.029701010839118254,0.23558336378029476,0.20588235294117652
CSNK1A1L,ENSG00000180138,3.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.4,3,0.5,47,3.4,0.0,0.0,0.0,8,0.5,39,6.8,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,False,False,31,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.014565826330532213,0.22044817927170873,0.20588235294117652
OR52D1,ENSG00000181609,1.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.1,3,0.0,47,1.1,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
ACTL9,ENSG00000181786,108.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,108.6,3,0.0,47,108.6,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_testis_biased,False,True,31,20,,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
ADIG,ENSG00000182035,52.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,52.0,3,2.4,47,52.0,0.0,0.0,2.4,8,1.0,39,21.666666666666668,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,GBM:TCGA|GBM:validation|KIRP:TCGA|THCA:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.018181818181818184,0.018181818181818184,0.0,0.0,0.3076923076923077,0.3076923076923077,0.012386377475891542,0.21826873041706807,0.20588235294117652
ZNF716,ENSG00000182111,0.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.4,3,0.1,47,0.4,0.0,0.0,0.1,8,0.1,39,4.0,False,2,0,Cancer-germline,10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Wang2016_CT,True,False,31,0,BLCA:TCGA|CESC:TCGA|GBM:validation|KIRP:TCGA|LIHC:validation|OV:TCGA|PAAD:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
SPACA6,ENSG00000182310,7.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,False,False,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.2,3,1.3,47,7.2,0.4,0.5,0.8,8,1.3,39,5.538461538461538,False,0,0,,,,True,False,29,0,BLCA:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:validation|OV:TCGA|OV:validation|PAAD:validation|READ:validation|STAD:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013594074339560655,0.013594074339560655,0.0,0.01917465847824226,0.32686696617054994,0.3076923076923077,0.06362556880459694,0.2695079217457734,0.20588235294117652
POTEC,ENSG00000183206,2.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.4,3,0.0,47,2.4,0.0,0.0,0.0,8,0.0,39,,True,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:validation|PAAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
FAM9A,ENSG00000183304,4.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.2,3,0.8,47,4.2,0.0,0.0,0.0,8,0.8,39,5.25,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,LIHC:validation|STAD:TCGA,colorectal cancer|prostate cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.03612947155146643,0.24201182449264294,0.20588235294117652
MAGEA2B,ENSG00000183305,1.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.9,3,0.0,47,1.9,0.0,0.1,0.0,8,0.0,39,,True,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/ncomms10499|10.18632/oncotarget.21715,Jamin2021_CT|Jamin2021_core|Wang2016_CT|daSilva2017_testis_biased,True,False,30,0,BLCA:TCGA|BRCA:TCGA|COAD:TCGA|COAD:validation|HNSC:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TMEM89,ENSG00000183396,24.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,24.1,3,1.7,47,24.1,0.0,0.0,0.1,8,1.7,39,14.176470588235295,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|COAD:TCGA|COAD:validation|READ:TCGA|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.011765836777852543,0.011765836777852543,0.0,0.016573170419324268,0.324265478111632,0.3076923076923077,0.06285149667502608,0.2687338496162026,0.20588235294117652
TFDP3,ENSG00000183434,4.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.1,3,0.1,47,4.1,0.0,0.0,0.1,8,0.0,39,40.99999999999999,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:TCGA|BRCA:validation|LIHC:TCGA|LIHC:validation|SKCM:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
MEX3B,ENSG00000183496,45.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,45.5,3,13.6,47,45.5,7.0,2.2,13.6,8,6.3,39,3.3455882352941178,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.16618264008387715,0.16618264008387715,0.0,0.13879258073246026,0.44648488842476797,0.3076923076923077,0.2782889286910011,0.4841712816321776,0.20588235294117652
OR4N4,ENSG00000183706,7.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.8,3,0.0,47,7.8,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
BPY2,ENSG00000183753,1.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.1,3,0.2,47,1.1,0.0,0.0,0.0,8,0.2,39,5.5,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0053475935828877,0.2112299465240642,0.20588235294117652
CNGA2,ENSG00000183862,0.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.2,3,0.0,47,0.2,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation,endometrial cancer|liver cancer|pancreatic cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
SPATA32,ENSG00000184361,42.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,42.4,3,0.5,47,42.4,0.0,0.0,0.1,8,0.5,39,84.8,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,29,20,BLCA:TCGA|CESC:TCGA|GBM:validation|LUAD:TCGA|LUAD:validation|PRAD:TCGA,breast cancer|colorectal cancer|lymphoma|pancreatic cancer|skin cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0074054272890867285,0.31509773498139443,0.3076923076923077,0.020753756047873696,0.2266361089890502,0.20588235294117652
OR56A3,ENSG00000184478,0.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.1,3,0.0,47,0.1,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:validation|LIHC:validation|OV:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
SPEM2,ENSG00000184560,124.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,124.5,3,0.2,47,124.5,0.0,0.0,0.1,8,0.2,39,622.5,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,29,20,,cervical cancer|colorectal cancer|endometrial cancer|ovarian cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.00582505729564553,0.21170741023682205,0.20588235294117652
PIWIL3,ENSG00000184571,0.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.8,3,0.2,47,0.8,0.4,0.0,0.0,8,0.2,39,4.0,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|LUAD:TCGA|PAAD:validation|TGCT:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
PRR23B,ENSG00000184814,1.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.2,3,0.0,47,1.2,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
NT5C1B,ENSG00000185013,34.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,True,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,34.5,3,1.0,47,34.5,0.0,0.2,0.2,8,1.0,39,34.5,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PRAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA,breast cancer|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|lung cancer|ovarian cancer|pancreatic cancer|prostate cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern|Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03716769697860386,0.03716769697860386,0.0,0.030151649523800013,0.3378439572161077,0.3076923076923077,0.07353275454298472,0.2794151074841612,0.20588235294117652
ZNF479,ENSG00000185177,2.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.7,3,0.1,47,2.7,0.0,0.0,0.0,8,0.1,39,27.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0042016806722689065,0.2100840336134454,0.20588235294117652
FAM47A,ENSG00000185448,2.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.8,3,0.0,47,2.8,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,False,True,31,20,,breast cancer|colorectal cancer|endometrial cancer|glioma|lung cancer|ovarian cancer|prostate cancer|skin cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
SPATA31A6,ENSG00000185775,1.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.9,3,0.0,47,1.9,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,29,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
NPAP1,ENSG00000185823,2.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.8,3,0.8,47,2.8,0.5,0.0,0.1,8,0.8,39,3.4999999999999996,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,29,20,BLCA:TCGA|COAD:validation|PAAD:validation|READ:validation|TGCT:TCGA|UCEC:TCGA,colorectal cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.015425576171062487,0.015425576171062487,0.0,0.0037831021437578823,0.3114754098360656,0.3076923076923077,0.06153649206718261,0.2674188450083591,0.20588235294117652
ZNF829,ENSG00000185869,10.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.1,3,2.0,47,10.1,2.2,1.4,2.0,8,1.9,39,5.05,False,0,0,,,,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1299240348613967,0.1299240348613967,0.0,0.10322961305239056,0.41092192074469824,0.3076923076923077,0.2364220005512974,0.4423043534924739,0.20588235294117652
PRSS38,ENSG00000185888,4.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.1,3,0.1,47,4.1,0.0,0.0,0.0,8,0.1,39,40.99999999999999,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_testis_biased,False,False,31,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0003501400560224089,0.20623249299719892,0.20588235294117652
FAM186A,ENSG00000185958,13.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.8,3,1.1,47,13.8,0.2,0.0,0.3,8,1.1,39,12.545454545454545,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|KICH:TCGA|KIRC:TCGA|KIRP:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.015610881476497165,0.015610881476497165,0.0,0.011227270878249197,0.3189195785705569,0.3076923076923077,0.12871903299100754,0.334601385932184,0.20588235294117652
CCIN,ENSG00000185972,72.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,72.6,3,1.8,47,72.6,0.1,0.5,1.1,8,1.8,39,40.33333333333333,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:TCGA|BRCA:validation|GBM:TCGA|GBM:validation|OV:TCGA|OV:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.007692307692307693,0.007692307692307693,0.0,0.011072184029613963,0.3187644917219217,0.3076923076923077,0.08150025144237016,0.2873826043835467,0.20588235294117652
ZPBP2,ENSG00000186075,92.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,92.5,3,0.9,47,92.5,0.0,0.0,0.1,8,0.9,39,102.77777777777777,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,CESC:TCGA|COAD:validation|HNSC:TCGA|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.00788196466705494,0.00788196466705494,0.0,0.013080875571700139,0.32077318326400783,0.3076923076923077,0.024854961747544865,0.23073731468872138,0.20588235294117652
ARGFX,ENSG00000186103,0.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.3,3,1.0,47,0.3,0.1,0.2,0.2,8,1.0,39,0.3,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|CESC:TCGA|COAD:validation|KICH:TCGA|KIRC:TCGA|KIRP:TCGA|LUAD:TCGA|LUSC:TCGA|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.024811121515232272,0.024811121515232272,0.0,0.019659225403540582,0.3273515330958483,0.3076923076923077,0.06578951738798286,0.2716718703291594,0.20588235294117652
CCDC73,ENSG00000186714,3.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.7,3,0.4,47,3.7,0.5,0.0,0.2,8,0.4,39,9.25,False,1,0,Cancer-germline,10.1038/s41388-018-0357-2,Bruggeman2018_GC,True,True,31,20,BLCA:TCGA|BRCA:validation|KIRC:validation|LIHC:validation|PRAD:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005825242718446602,0.005825242718446602,0.0,0.0,0.3076923076923077,0.3076923076923077,0.031453095072020903,0.23733544801319742,0.20588235294117652
SELENOV,ENSG00000186838,9.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.6,3,2.3,47,9.6,0.1,0.0,0.0,8,2.3,39,4.173913043478261,False,0,0,,,,True,True,29,20,GBM:TCGA|GBM:validation|OV:TCGA|OV:validation|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer|prostate cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02456140350877193,0.02456140350877193,0.0,0.022577067412145428,0.33026937510445314,0.3076923076923077,0.00897631779984721,0.21485867074102372,0.20588235294117652
TMEM262,ENSG00000187066,20.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,20.5,3,0.1,47,20.5,0.0,0.0,0.1,8,0.1,39,205.0,False,0,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,29,0,COAD:validation|OV:validation|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
H1-6,ENSG00000187475,1.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,True,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.0,3,0.1,47,1.0,0.0,0.0,0.1,8,0.1,39,10.0,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,29,20,BRCA:TCGA|COAD:validation|GBM:validation|KIRC:validation|PAAD:validation,testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.005952380952380952,0.21183473389355748,0.20588235294117652
DPPA3,ENSG00000187569,3.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.1,3,1.1,47,1.0,3.1,0.0,1.1,8,0.5,39,2.818181818181818,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.015966386554621848,0.22184873949579836,0.20588235294117652
SPATA31F3,ENSG00000187791,28.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,28.1,3,0.7,47,28.1,0.0,0.0,0.1,8,0.7,39,40.142857142857146,False,0,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,29,0,KIRC:TCGA|KIRC:validation|LUSC:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.007805440738248582,0.007805440738248582,0.0,0.007178193811232904,0.3148705015035406,0.3076923076923077,0.04067068197502979,0.2465530349162063,0.20588235294117652
DAZ1,ENSG00000188120,2.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.0,3,0.2,47,2.0,0.0,0.0,0.0,8,0.2,39,10.0,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.18632/oncotarget.21715,Jamin2021_CT|Jamin2021_core|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,PAAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
NUTM2G,ENSG00000188152,2.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; No source-backed cancer/reproductive candidate nomination,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.8,3,0.7,47,2.8,0.4,0.1,0.3,8,0.7,39,4.0,False,0,0,,,,True,False,29,0,COAD:validation|KIRC:validation|OV:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.026714795606227894,0.026714795606227894,0.0,0.018433179723502304,0.32612548741581,0.3076923076923077,0.08501532804601858,0.2908976809871951,0.20588235294117652
POTEE,ENSG00000188219,1.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; No source-backed cancer/reproductive candidate nomination,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.3,3,0.3,47,1.3,0.0,0.1,0.3,8,0.1,39,4.333333333333334,False,0,0,,,,True,True,31,20,BRCA:validation|PAAD:validation|PRAD:TCGA|READ:validation|STAD:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
LRRIQ4,ENSG00000188306,2.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.8,3,0.4,47,2.8,0.1,0.0,0.2,8,0.4,39,6.999999999999999,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|LUAD:TCGA|LUAD:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|STAD:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|liver cancer|lung cancer|ovarian cancer|pancreatic cancer|stomach cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.009927495384925317,0.31761980307723303,0.3076923076923077,0.01282785841609371,0.21871021135727023,0.20588235294117652
PPP3R2,ENSG00000188386,78.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,78.6,3,0.1,47,78.6,0.0,0.0,0.1,8,0.1,39,785.9999999999999,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,31,20,,breast cancer|colorectal cancer|endometrial cancer|liver cancer|melanoma|ovarian cancer|renal cancer|skin cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
MAGEB16,ENSG00000189023,3.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.1,3,0.0,47,3.1,0.0,0.0,0.0,8,0.0,39,,True,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,SKCM:TCGA|TGCT:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|ovarian cancer|pancreatic cancer|skin cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
FAM47B,ENSG00000189132,9.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.0,3,0.0,47,9.0,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,True,31,20,,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
ZAR1L,ENSG00000189167,0.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.7,3,0.1,47,0.7,0.1,0.0,0.0,8,0.1,39,6.999999999999999,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,TGCT:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
FOXR2,ENSG00000189299,1.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,True,legacy-03 | legacy-04,https://pmc.ncbi.nlm.nih.gov/articles/PMC9437574/,legacy-03 | legacy-04,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.2,3,0.1,47,1.2,0.0,0.0,0.1,8,0.0,39,11.999999999999998,False,2,0,Cancer-germline|Cancer-reproductive,10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,TGCT:TCGA,endometrial cancer|glioma|melanoma|renal cancer|thyroid cancer,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
SPANXN4,ENSG00000189326,25.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,25.2,3,0.0,47,25.2,0.0,0.0,0.0,8,0.0,39,,True,0,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_testis_biased,False,True,31,20,,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
OR8A1,ENSG00000196119,0.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.2,3,0.9,47,0.2,0.1,0.1,0.3,8,0.9,39,0.22222222222222224,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|CESC:TCGA|COAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.019202719384036074,0.019202719384036074,0.0,0.011227270878249197,0.3189195785705569,0.3076923076923077,0.060393342289894014,0.26627569523107053,0.20588235294117652
OR10J1,ENSG00000196184,6.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.8,3,0.0,47,6.8,0.0,0.0,0.0,8,0.0,39,,True,0,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,31,0,CESC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
OR2C3,ENSG00000196242,0.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.7,3,0.4,47,0.7,0.0,0.1,0.1,8,0.4,39,1.7499999999999998,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,0,SKCM:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.01610644257703081,0.22198879551820733,0.20588235294117652
ZNF729,ENSG00000196350,1.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.9,3,0.1,47,1.9,0.0,0.0,0.1,8,0.0,39,18.999999999999996,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Gong2021_reproductive_PC|Loriot2025_S1|daSilva2017_testis_biased,True,False,30,0,GBM:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
NBPF4,ENSG00000196427,4.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.3,3,1.1,47,4.3,0.0,0.5,0.6,8,1.1,39,3.9090909090909087,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Jamin2021_core|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|COAD:TCGA|COAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA,breast cancer|colorectal cancer|endometrial cancer|melanoma|pancreatic cancer|prostate cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.006144393241167435,0.31383670093347515,0.3076923076923077,0.03540660519251394,0.24128895813369045,0.20588235294117652
GK2,ENSG00000196475,86.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,86.9,3,0.0,47,86.9,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,31,20,,endometrial cancer|liver cancer|prostate cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
POTEF,ENSG00000196604,1.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.7,3,0.2,47,1.7,0.0,0.1,0.1,8,0.2,39,8.5,False,2,0,Cancer-germline,10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Loriot2025_S1|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|COAD:validation|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0053475935828877,0.2112299465240642,0.20588235294117652
POTEI,ENSG00000196834,3.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.2,3,2.4,47,3.2,0.0,0.1,2.4,8,0.4,39,1.3333333333333335,False,1,0,Cancer-germline,10.1002/cam4.2223,Chang2019_TGCT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|COAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,False,True,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.016806722689075633,0.22268907563025214,0.20588235294117652
RGPD4,ENSG00000196862,3.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.6,3,1.0,47,3.6,0.1,0.0,0.8,8,1.0,39,3.6,False,3,0,Cancer-germline|Cancer-reproductive,10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Bruggeman2018_GC|Carter2023_CT|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BRCA:validation|GBM:validation|KIRC:validation|LIHC:validation|PAAD:TCGA|PRAD:TCGA|READ:validation,colorectal cancer|glioma|liver cancer|melanoma|ovarian cancer|renal cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.015687405405303525,0.015687405405303525,0.0,0.012449563480763905,0.32014187117307163,0.3076923076923077,0.03838808250572956,0.24427043544690608,0.20588235294117652
ZNF679,ENSG00000197123,1.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.0,3,0.0,47,1.0,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,GBM:TCGA|GBM:validation|LUAD:validation|LUSC:validation|OV:TCGA|OV:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
DMBX1,ENSG00000197587,0.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.9,3,0.7,47,0.9,0.0,0.0,0.1,8,0.7,39,1.2857142857142858,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005901766647252961,0.005901766647252961,0.0,0.0037424236260830655,0.3114347313183908,0.3076923076923077,0.026535762948806427,0.23241811588998296,0.20588235294117652
ZNF560,ENSG00000198028,6.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.0,3,2.0,47,6.0,0.0,0.7,0.0,8,2.0,39,3.0,False,6,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,0,BLCA:TCGA|GBM:TCGA|GBM:validation|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PRAD:TCGA|SKCM:TCGA|TGCT:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.014705882352941176,0.2205882352941177,0.20588235294117652
TUBA3C,ENSG00000198033,393.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,393.6,3,0.5,47,393.6,0.0,0.0,0.2,8,0.5,39,787.2,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BLCA:TCGA|BRCA:validation|LIHC:TCGA|LIHC:validation|LUAD:TCGA|SKCM:TCGA|STAD:TCGA|TGCT:TCGA,breast cancer|carcinoid|colorectal cancer|endometrial cancer|glioma|head and neck cancer|melanoma|prostate cancer|skin cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005940594059405941,0.005940594059405941,0.0,0.00591715976331361,0.3136094674556213,0.3076923076923077,0.013496307613954671,0.2193786605551312,0.20588235294117652
POTEH,ENSG00000198062,1.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.7,3,1.6,47,0.7,0.0,0.0,1.6,8,0.0,39,0.43749999999999994,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,PRAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
FAM47C,ENSG00000198173,2.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.8,3,0.1,47,2.8,0.0,0.0,0.0,8,0.1,39,27.999999999999996,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
,ENSG00000198211,6.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.4,3,0.5,47,6.4,0.0,0.0,0.3,8,0.5,39,12.8,False,0,0,,,,True,True,29,20,CESC:TCGA|COAD:validation|GBM:TCGA|KIRP:TCGA|OV:TCGA|OV:validation|READ:validation|SKCM:TCGA|UCEC:TCGA,breast cancer|colorectal cancer|glioma|lung cancer|melanoma|pancreatic cancer|skin cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013484205563413485,0.013484205563413485,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.024192878732520677,0.2300752316736972,0.20588235294117652
TMEM239,ENSG00000198326,103.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,103.4,3,0.8,47,103.4,0.0,0.1,0.2,8,0.8,39,129.25,False,0,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,29,0,BLCA:TCGA|CESC:TCGA|KICH:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.008403361344537816,0.21428571428571433,0.20588235294117652
GPX6,ENSG00000198704,3.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.1,3,3.2,47,0.1,0.0,0.0,3.2,8,0.0,39,0.03125,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
SAXO5,ENSG00000198723,20.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,20.0,3,1.6,47,20.0,0.1,0.2,0.3,8,1.6,39,12.5,False,4,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|LUAD:TCGA|LUAD:validation|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.030890814224577064,0.030890814224577064,0.0,0.01489027454125286,0.32258258223356057,0.3076923076923077,0.12202909929892027,0.32791145224009677,0.20588235294117652
STKLD1,ENSG00000198870,9.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.7,3,0.6,47,9.7,0.3,0.0,0.3,8,0.6,39,16.166666666666668,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,29,20,COAD:validation|GBM:validation|OV:validation|PAAD:validation|READ:validation|SKCM:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.011803533294505923,0.011803533294505923,0.0,0.01000691534800472,0.31769922304031245,0.3076923076923077,0.06522217126437074,0.27110452420554726,0.20588235294117652
DPPA5,ENSG00000203909,2.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.0,3,0.5,47,2.0,0.6,0.0,0.0,8,0.5,39,4.0,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_testis_biased,True,True,31,20,OV:validation|TGCT:TCGA,colorectal cancer|glioma|head and neck cancer|melanoma|ovarian cancer|skin cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.0,0.3076923076923077,0.3076923076923077,0.011764705882352941,0.21764705882352947,0.20588235294117652
C1orf146,ENSG00000203910,7.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.3,3,2.0,47,7.3,0.1,0.0,0.0,8,2.0,39,3.65,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,COAD:validation|READ:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013300952736783113,0.013300952736783113,0.0,0.006264491721921653,0.3139567994142294,0.3076923076923077,0.028999346774282835,0.23488169971545936,0.20588235294117652
SPANXN1,ENSG00000203923,1.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.4,3,0.0,47,1.4,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,False,31,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
GLT6D1,ENSG00000204007,4.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.6,3,0.1,47,4.6,0.0,0.0,0.1,8,0.0,39,45.99999999999999,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,False,True,31,20,,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
LIPJ,ENSG00000204022,6.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.8,3,0.9,47,6.8,0.0,0.0,0.9,8,0.5,39,7.555555555555555,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,GBM:validation,breast cancer|colorectal cancer|pancreatic cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.025098081883172158,0.025098081883172158,0.0,0.016031210108417935,0.32372351780072567,0.3076923076923077,0.05292982805770529,0.2588121809988818,0.20588235294117652
OR13C3,ENSG00000204246,0.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,False,False,False,False,False,False,Neither,Unassessed,The declared measurement panel or reference coverage is incomplete,The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Unassessed,The declared measurement panel or reference coverage is incomplete,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.1,3,0.0,38,0.1,0.0,0.0,0.0,7,0.0,31,,True,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.36764705882352944,0.36764705882352944
PAGE3,ENSG00000204279,7.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.4,3,0.0,47,7.4,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,True,31,20,,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
SPATA31J1,ENSG00000204661,,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,False,False,False,False,False,False,Neither,Unassessed,The declared measurement panel or reference coverage is incomplete,The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Unassessed,The declared measurement panel or reference coverage is incomplete,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,,0,,0,,,,,0,,0,,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,0,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,1.0,1.0,0.0,1.0,1.0,0.0,1.0,1.0
IL31,ENSG00000204671,0.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,True,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.1,3,0.0,47,0.1,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,31,20,,breast cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern|Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
OR11A1,ENSG00000204694,0.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.0,3,0.0,47,0.0,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
FBXO47,ENSG00000204952,3.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.8,3,0.0,47,3.8,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
PCDHA9,ENSG00000204961,1.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.1,3,0.8,47,1.1,0.0,0.0,0.1,8,0.8,39,1.375,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,0,BLCA:TCGA|BRCA:validation|GBM:TCGA|GBM:validation|LIHC:validation|PAAD:validation|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.0,0.3076923076923077,0.3076923076923077,0.04237117552334944,0.24825352846452595,0.20588235294117652
MS4A13,ENSG00000204979,3.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.4,3,0.0,47,3.4,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,True,31,20,,breast cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CDKL4,ENSG00000205111,2.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,True,True,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.0,3,0.7,47,2.0,0.0,0.2,0.2,8,0.7,39,2.857142857142857,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BRCA:validation|COAD:validation|GBM:validation|PAAD:validation|READ:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern|Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.04222750584643167,0.2481098587876082,0.20588235294117652
LRRC72,ENSG00000205858,2.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.5,3,0.0,47,2.5,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,True,29,20,,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
DAZ2,ENSG00000205944,2.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,True,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.9,3,5.2,47,2.9,0.0,0.0,0.0,8,5.2,39,0.5576923076923077,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.18632/oncotarget.21715,Jamin2021_CT|Jamin2021_core|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,GBM:TCGA|KIRC:validation|PAAD:TCGA|PAAD:validation|SKCM:TCGA|STAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.03571428571428572,0.3434065934065934,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
KRTAP20-4,ENSG00000206105,2.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; No source-backed cancer/reproductive candidate nomination,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.0,3,0.0,47,2.0,0.0,0.0,0.0,8,0.0,39,,True,0,0,,,,True,False,29,0,LIHC:TCGA|LUSC:validation|PRAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TSSK2,ENSG00000206203,132.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,132.1,3,0.5,47,132.1,0.0,0.0,0.1,8,0.5,39,264.2,False,0,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_testis_biased,True,False,31,0,CESC:TCGA|LIHC:validation|PRAD:TCGA|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.020263559969442322,0.22614591291061883,0.20588235294117652
PRR23A,ENSG00000206260,1.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.5,3,0.1,47,1.5,0.1,0.0,0.0,8,0.1,39,15.0,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,CESC:TCGA|KICH:TCGA|PAAD:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
TRIM71,ENSG00000206557,4.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.7,3,0.8,47,4.7,0.1,0.2,0.1,8,0.8,39,5.875,False,4,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,COAD:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|OV:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.05204077678502231,0.2579231297261988,0.20588235294117652
CTAGE1,ENSG00000212710,10.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.0,3,0.0,47,10.0,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,False,True,31,20,,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CCDC183,ENSG00000213213,21.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,21.4,3,1.8,47,21.4,1.1,0.7,1.8,8,1.6,39,11.888888888888888,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.18632/oncotarget.21715,Jamin2021_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,29,20,BRCA:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|LIHC:TCGA|LUAD:TCGA|LUAD:validation|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA,breast cancer|colorectal cancer|glioma|ovarian cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.05332127726395834,0.05332127726395834,0.0,0.05763381355105225,0.36532612124335995,0.3076923076923077,0.13313582789286113,0.3390181808340377,0.20588235294117652
TSGA13,ENSG00000213265,13.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.6,3,0.1,47,13.6,0.0,0.0,0.1,8,0.0,39,136.0,False,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC,True,True,31,20,KICH:TCGA|PAAD:validation|UCEC:TCGA,melanoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
ZNF99,ENSG00000213973,1.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; No source-backed cancer/reproductive candidate nomination,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.6,3,0.2,47,1.6,0.1,0.0,0.2,8,0.2,39,8.0,False,0,0,,,,True,False,31,0,BLCA:TCGA|BRCA:validation|CESC:TCGA|GBM:validation|KICH:TCGA|LIHC:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005940594059405941,0.005940594059405941,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.010472370766488413,0.21635472370766493,0.20588235294117652
SPDYE3,ENSG00000214300,2.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.4,3,0.1,47,2.4,0.0,0.0,0.0,8,0.1,39,23.999999999999996,False,1,0,Cancer-germline,10.1038/s41388-018-0357-2,Bruggeman2018_GC,True,False,31,20,BRCA:validation|COAD:validation|LIHC:validation|OV:validation|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.011554621848739495,0.217436974789916,0.20588235294117652
SPATA31D1,ENSG00000214929,10.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.8,3,0.0,47,10.8,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,False,True,29,20,,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|liver cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CXorf49B,ENSG00000215113,4.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.6,3,0.0,47,4.6,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline,10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Loriot2025_S1|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:validation|OV:validation|PAAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CXorf49,ENSG00000215115,3.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.3,3,0.0,47,3.3,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline,10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Loriot2025_S1|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,30,0,OV:validation|PAAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
GOLGA6B,ENSG00000215186,7.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,True,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.0,3,4.2,47,7.0,0.0,0.0,0.2,8,4.2,39,1.6666666666666665,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,BRCA:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.0,0.3076923076923077,0.3076923076923077,0.05277293245488939,0.2586552853960659,0.20588235294117652
ZNF705D,ENSG00000215343,3.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.3,3,3.2,47,0.3,0.0,0.0,3.2,8,0.0,39,0.09374999999999999,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
EFCAB8,ENSG00000215529,3.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,True,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.3,3,0.3,47,3.3,0.0,0.0,0.1,8,0.3,39,11.0,False,1,0,Cancer-germline,10.1371/journal.pgen.1011734,Loriot2025_S2,True,True,29,20,COAD:validation|GBM:validation|OV:validation|PAAD:validation|READ:validation,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern|Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013707207385501543,0.013707207385501543,0.0,0.005044136191677176,0.31273644388398486,0.3076923076923077,0.026899890390938982,0.2327822433321155,0.20588235294117652
GAB4,ENSG00000215568,2.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.0,3,0.1,47,2.0,0.0,0.0,0.0,8,0.1,39,20.0,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,OV:validation,breast cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
ZC3H11B,ENSG00000215817,4.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.8,3,0.3,47,4.8,0.1,0.0,0.1,8,0.3,39,16.0,False,1,0,Cancer-germline,10.1371/journal.pgen.1011734,Loriot2025_S1,True,True,29,20,GBM:TCGA|GBM:validation|SKCM:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.015686274509803925,0.015686274509803925,0.0,0.007525525769840948,0.31521783346214866,0.3076923076923077,0.05325588733517122,0.25913824027634774,0.20588235294117652
TDRD15,ENSG00000218819,5.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.3,3,0.9,47,5.3,0.0,0.0,0.0,8,0.9,39,5.888888888888888,False,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,29,20,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.018255578093306288,0.22413793103448282,0.20588235294117652
SPATA31H1,ENSG00000221843,5.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.5,3,1.5,47,5.5,0.2,0.0,0.2,8,1.5,39,3.6666666666666665,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1136/jitc-2023-007935,Carter2023_CT|Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|COAD:validation|GBM:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.00788196466705494,0.00788196466705494,0.0,0.008786559817760243,0.31647886751006793,0.3076923076923077,0.05026654930747002,0.25614890224864656,0.20588235294117652
OR3A2,ENSG00000221882,2.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,False,False,False,False,False,False,Neither,Unassessed,The declared measurement panel or reference coverage is incomplete,The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Unassessed,The declared measurement panel or reference coverage is incomplete,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.8,3,0.9,38,2.8,0.2,0.1,0.3,7,0.9,31,3.1111111111111107,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1136/jitc-2023-007935,Carter2023_CT|Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|CESC:TCGA|GBM:validation|KICH:TCGA|KIRP:TCGA|OV:TCGA|OV:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.011727009365699564,0.011727009365699564,0.0,0.003663003663003663,0.31135531135531136,0.3076923076923077,0.021177174018033,0.3888242328415624,0.36764705882352944
OR1C1,ENSG00000221888,2.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.5,3,0.2,47,2.5,0.0,0.0,0.0,8,0.2,39,12.5,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.005474917239623121,0.21135727018079964,0.20588235294117652
CDRT15,ENSG00000223510,20.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,True,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,20.3,3,3.2,47,20.3,0.1,0.1,0.2,8,3.2,39,6.34375,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|KIRC:TCGA|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern|Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0765026174963499,0.0765026174963499,0.0,0.043505672930290375,0.3511979806225981,0.3076923076923077,0.08659754567682956,0.29247989861800605,0.20588235294117652
EBLN1,ENSG00000223601,2.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.7,3,0.1,47,2.7,0.0,0.0,0.0,8,0.1,39,27.0,False,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,False,30,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.007352941176470587,0.2132352941176471,0.20588235294117652
PPP4R3C,ENSG00000224960,1.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.8,3,0.0,47,1.8,0.0,0.2,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734,Carter2023_CT|Gong2021_reproductive_PC|Loriot2025_S1,True,False,29,0,BLCA:TCGA|LIHC:TCGA|LUSC:TCGA|SKCM:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TEX22,ENSG00000226174,4.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,False,True,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.8,3,1.0,47,4.8,0.6,0.1,0.4,8,1.0,39,4.8,False,0,0,,,,True,False,30,20,BLCA:TCGA|BRCA:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|OV:TCGA|OV:validation|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04317095287214788,0.04317095287214788,0.0,0.016034963185941505,0.3237272708782492,0.3076923076923077,0.07357648745116775,0.27945884039234425,0.20588235294117652
KIF4B,ENSG00000226650,3.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.4,3,0.0,47,3.4,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,GBM:validation|TGCT:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
ANHX,ENSG00000227059,4.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.8,3,0.0,47,4.8,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,29,0,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
GK3,ENSG00000229894,12.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,12.7,3,0.4,47,12.7,0.0,0.0,0.0,8,0.4,39,31.749999999999996,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935,Bruggeman2018_GC|Carter2023_CT|Gong2021_reproductive_PC|Jamin2021_CT,True,True,31,20,BRCA:validation|COAD:validation|READ:validation,endometrial cancer|liver cancer|prostate cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.015406162464985995,0.2212885154061625,0.20588235294117652
TEX53,ENSG00000230054,66.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,66.3,3,0.4,47,66.3,0.0,0.0,0.1,8,0.4,39,165.74999999999997,False,0,0,Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_reproductive_PC,True,False,29,0,COAD:validation|PRAD:TCGA|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013594074339560655,0.013594074339560655,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.01502557544757033,0.22090792838874684,0.20588235294117652
TEX48,ENSG00000230601,25.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,25.7,3,0.2,47,25.7,0.0,0.0,0.0,8,0.2,39,128.5,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Gong2021_reproductive_PC|Loriot2025_S1|daSilva2017_testis_biased,True,False,29,0,LUAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0006684491978609625,0.20655080213903748,0.20588235294117652
SCAND3,ENSG00000232040,8.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.5,3,3.0,47,8.5,1.1,0.6,3.0,8,1.9,39,2.8333333333333335,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04118028123611238,0.04118028123611238,0.0,0.038681853134332894,0.34637416082664063,0.3076923076923077,0.13855143090767214,0.34443378384884865,0.20588235294117652
PRAMEF6,ENSG00000232423,0.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.0,3,0.0,47,0.0,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
BTBD18,ENSG00000233436,2.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.1,3,0.2,47,2.1,0.0,0.0,0.0,8,0.2,39,10.5,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BRCA:validation|COAD:validation|OV:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA,glioma|liver cancer|melanoma|testis cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.0,0.3076923076923077,0.3076923076923077,0.01117265087853323,0.21705500381970974,0.20588235294117652
IQCM,ENSG00000234828,4.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.4,3,0.3,47,4.4,0.0,0.0,0.0,8,0.3,39,14.666666666666668,False,0,0,Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_reproductive_PC,True,False,29,0,COAD:validation|GBM:validation|PAAD:validation|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.007326007326007326,0.315018315018315,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CTAGE9,ENSG00000236761,8.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.1,3,0.2,47,8.1,0.0,0.0,0.2,8,0.2,39,40.49999999999999,False,2,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|COAD:validation|KIRC:TCGA|KIRC:validation|READ:validation|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
MEIOSIN,ENSG00000237452,7.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.1,3,0.3,47,7.1,0.0,0.0,0.0,8,0.3,39,23.666666666666668,False,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,29,20,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.007672634271099744,0.21355498721227625,0.20588235294117652
OR7E24,ENSG00000237521,1.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.8,3,0.0,47,1.8,0.1,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
MPC1L,ENSG00000238205,17.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,17.9,3,0.0,47,17.9,0.0,0.0,0.0,8,0.0,39,,True,0,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,29,0,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
ETDA,ENSG00000238210,17.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,False,False,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,17.0,3,0.7,47,17.0,0.0,0.0,0.1,8,0.7,39,24.28571428571429,False,0,0,,,,True,False,29,0,COAD:validation|READ:validation|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.01506431016933469,0.01506431016933469,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.02737597015090621,0.23325832309208272,0.20588235294117652
TEX35,ENSG00000240021,114.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,114.7,3,1.8,47,114.7,0.2,0.2,0.7,8,1.8,39,63.72222222222222,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,29,20,COAD:validation|KIRC:validation|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA,liver cancer|melanoma|pancreatic cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.052979765303064454,0.052979765303064454,0.0,0.039093662077533044,0.3467859697698408,0.3076923076923077,0.09031160206957757,0.2961939550107541,0.20588235294117652
ZNF722,ENSG00000241149,1.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.7,3,0.1,47,1.7,0.0,0.0,0.0,8,0.1,39,17.0,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734,Gong2021_reproductive_PC|Loriot2025_S1,True,False,29,0,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
RTL9,ENSG00000243978,7.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.6,3,1.2,47,7.6,1.1,0.4,0.1,8,1.2,39,6.333333333333333,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,20,GBM:validation|KICH:TCGA|SKCM:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.0,0.3076923076923077,0.3076923076923077,0.04483104359584229,0.2507133965370188,0.20588235294117652
SPMAP2L,ENSG00000249693,3.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.4,3,0.5,47,3.4,0.0,0.0,0.2,8,0.5,39,6.8,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1136/jitc-2023-007935,Carter2023_CT|Chang2019_TGCT,True,True,29,20,GBM:validation|SKCM:TCGA,breast cancer|cervical cancer|endometrial cancer|glioma|liver cancer|lung cancer|pancreatic cancer|prostate cancer|renal cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005825242718446602,0.005825242718446602,0.0,0.004962779156327543,0.31265508684863524,0.3076923076923077,0.019437340153452685,0.2253196930946292,0.20588235294117652
FER1L5,ENSG00000249715,4.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; No source-backed cancer/reproductive candidate nomination,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.0,3,1.0,47,4.0,0.1,0.0,0.4,8,1.0,39,4.0,False,0,0,,,,True,False,31,0,BRCA:validation|GBM:validation|LUAD:validation|OV:validation|PAAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.016074611662846953,0.22195696460402348,0.20588235294117652
GOLGA8K,ENSG00000249931,6.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,False,False,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.4,3,1.4,47,6.4,0.4,0.0,0.5,8,1.4,39,4.571428571428572,False,0,0,,,,True,False,29,0,PAAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04972364516375002,0.04972364516375002,0.0,0.03163942137267199,0.3393317290649797,0.3076923076923077,0.12223248098018186,0.3281148339213584,0.20588235294117652
TERB1,ENSG00000249961,12.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,12.2,3,1.4,47,12.2,0.1,0.1,0.2,8,1.4,39,8.714285714285714,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.023047764082680697,0.023047764082680697,0.0,0.011147850915169795,0.3188401586074775,0.3076923076923077,0.051506082553923686,0.2573884354951002,0.20588235294117652
CCDC169-SOHLH2,ENSG00000250709,9.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.9,3,0.4,47,9.9,0.0,0.0,0.4,8,0.4,39,24.75,False,0,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_testis_biased,True,False,29,0,GBM:TCGA|PRAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.007446105806761545,0.31513841349906924,0.3076923076923077,0.018652915711739243,0.22453526865291576,0.20588235294117652
NT5C1B-RDH14,ENSG00000250741,16.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.1,3,0.1,47,16.1,0.0,0.0,0.0,8,0.1,39,161.0,False,1,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_testis_biased|daSilva2017_tumor_proteomics,False,True,29,20,,breast cancer|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|lung cancer|ovarian cancer|pancreatic cancer|prostate cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
ZNF475,ENSG00000250803,98.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,98.3,3,2.0,47,98.3,0.0,0.0,2.0,8,0.2,39,49.15,False,0,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,29,0,GBM:validation|LUSC:validation|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0053475935828877,0.2112299465240642,0.20588235294117652
RFPL4B,ENSG00000251258,1.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.6,3,0.3,47,1.6,0.0,0.3,0.0,8,0.3,39,5.333333333333334,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|GBM:validation|KIRC:validation|LIHC:TCGA|LIHC:validation|TGCT:TCGA,breast cancer|colorectal cancer|pancreatic cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.007672634271099744,0.21355498721227625,0.20588235294117652
CCDC166,ENSG00000255181,4.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.0,3,0.1,47,4.0,0.0,0.0,0.0,8,0.1,39,40.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,30,20,,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0003501400560224089,0.20623249299719892,0.20588235294117652
NPIPB8,ENSG00000255524,17.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,True,True,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,17.6,3,2.0,47,17.6,1.6,0.0,1.6,8,2.0,39,8.8,False,0,0,,,,True,True,29,20,COAD:validation|GBM:TCGA|GBM:validation|OV:validation|PAAD:validation|READ:validation,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Antibody concern|Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.08390383435400378,0.08390383435400378,0.0,0.07563286195487756,0.38332516964718527,0.3076923076923077,0.23252684011998626,0.43840919306116277,0.20588235294117652
,ENSG00000257390,8.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.7,3,0.9,47,8.7,0.0,0.0,0.3,8,0.9,39,9.666666666666666,False,0,0,,,,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009785638758050563,0.009785638758050563,0.0,0.022099936464029538,0.32979224415633723,0.3076923076923077,0.06959379363030478,0.2754761465714813,0.20588235294117652
,ENSG00000259060,3.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.5,3,3.7,47,0.5,0.0,0.0,3.7,8,0.0,39,0.13513513513513511,False,1,0,Cancer-germline,10.1038/ncomms10499,Wang2016_CT,False,False,29,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,False,True,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
ARMH2,ENSG00000260286,13.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.0,3,1.0,47,13.0,0.0,0.0,0.6,8,1.0,39,13.0,False,1,0,Cancer-germline,10.1002/cam4.2223,Chang2019_TGCT,False,False,29,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013300952736783113,0.013300952736783113,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.024859943977591035,0.23074229691876755,0.20588235294117652
SMIM47,ENSG00000261341,210.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,210.2,3,8.7,47,210.2,0.2,0.2,2.5,8,8.7,39,24.160919540229887,False,0,0,Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_reproductive_PC,True,False,29,0,BRCA:TCGA|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:validation|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.11045390253311045,0.11045390253311045,0.0,0.01847385824117712,0.32616616593348485,0.3076923076923077,0.05263257628986529,0.2585149292310418,0.20588235294117652
TP53TG3B,ENSG00000261509,4.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.8,3,4.3,47,0.8,0.0,0.0,4.3,8,0.1,39,0.186046511627907,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|SKCM:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0003501400560224089,0.20623249299719892,0.20588235294117652
TMEM249,ENSG00000261587,26.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,False,True,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,26.9,3,1.5,47,26.9,0.0,0.0,0.1,8,1.5,39,17.933333333333334,False,0,0,,,,True,False,26,20,COAD:TCGA|OV:TCGA|READ:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.007525525769840948,0.31521783346214866,0.3076923076923077,0.05585394997159703,0.26173630291277356,0.20588235294117652
IGBP1C,ENSG00000266826,8.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.5,3,0.1,47,8.5,0.0,0.2,0.1,8,0.0,39,85.0,False,0,0,Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_reproductive_PC,True,True,29,20,TGCT:TCGA,breast cancer|cervical cancer|colorectal cancer|ovarian cancer|pancreatic cancer|urothelial cancer,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
MAGEA2,ENSG00000268606,4.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.1,3,0.0,47,4.1,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Jamin2021_CT|Jamin2021_core|Loriot2025_S1|daSilva2017_CT|daSilva2017_testis_biased,True,False,28,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|COAD:TCGA|COAD:validation|HNSC:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
FAM236B,ENSG00000268994,95.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,95.5,3,1.2,47,95.5,0.4,0.0,0.3,8,1.2,39,79.58333333333334,False,0,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_testis_biased,True,False,26,0,COAD:validation|GBM:TCGA|READ:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.025350140056022413,0.025350140056022413,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.01342652445593622,0.21930887739711274,0.20588235294117652
ZNF728,ENSG00000269067,10.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,False,False,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.1,3,2.0,47,10.1,1.6,0.2,1.3,8,2.0,39,5.05,False,0,0,,,,True,False,29,0,COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|LIHC:TCGA|LUAD:validation|OV:TCGA|OV:validation|PAAD:validation|READ:validation|TGCT:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06301915905876303,0.06301915905876303,0.0,0.04976531099512428,0.357457618687432,0.3076923076923077,0.10239350483394732,0.30827585777512384,0.20588235294117652
CTAGE15,ENSG00000271079,7.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.8,3,1.7,47,7.8,0.3,0.0,0.6,8,1.7,39,4.588235294117647,False,0,0,,,,False,True,27,20,,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.05991181587225315,0.05991181587225315,0.0,0.037126925851493645,0.34481923354380134,0.3076923076923077,0.09024344037131761,0.2961257933124941,0.20588235294117652
CTAGE6,ENSG00000271321,14.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,14.0,3,0.2,47,14.0,0.1,0.0,0.1,8,0.2,39,70.0,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,True,28,20,BRCA:validation|GBM:validation,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.005602240896358543,0.21148459383753507,0.20588235294117652
,ENSG00000272297,29.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,False,False,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,29.3,3,2.0,47,29.3,0.1,0.0,2.0,8,0.6,39,14.65,False,0,0,,,,True,False,27,0,COAD:validation|GBM:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PRAD:TCGA|READ:validation|STAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.025974185660886426,0.23185653860206296,0.20588235294117652
RBAK-RBAKDN,ENSG00000272968,56.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,56.5,3,1.0,47,56.5,0.7,0.1,0.5,8,1.0,39,56.5,False,0,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_testis_biased,True,False,27,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.052737232092082954,0.052737232092082954,0.0,0.03824473099031558,0.34593703868262327,0.3076923076923077,0.11290316673948388,0.3187855196806604,0.20588235294117652
,ENSG00000273291,1.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; No source-backed cancer/reproductive candidate nomination,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.0,3,0.1,47,1.0,0.0,0.0,0.0,8,0.1,39,10.0,False,0,0,,,,True,False,27,0,GBM:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
GOLGA6L1,ENSG00000273976,27.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,27.6,3,0.5,47,27.6,0.0,0.0,0.0,8,0.5,39,55.2,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,True,28,20,READ:validation,melanoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0018207282913165266,0.20770308123249304,0.20588235294117652
ANTXRL,ENSG00000274209,12.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,12.4,3,1.0,47,12.4,0.0,0.0,0.5,8,1.0,39,12.4,False,0,0,Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_reproductive_PC,True,False,28,0,OV:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.028011204481792718,0.23389355742296924,0.20588235294117652
C8orf89,ENSG00000274443,7.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.6,3,1.0,47,7.6,0.6,0.3,0.9,8,1.0,39,7.6,False,0,0,,,,True,False,26,0,BRCA:TCGA|COAD:validation|LUAD:validation|OV:TCGA|READ:validation|SKCM:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03268144238263739,0.03268144238263739,0.0,0.021036604854690527,0.3287289125469982,0.3076923076923077,0.05597897413754191,0.26186132707871845,0.20588235294117652
RIMBP3B,ENSG00000274600,13.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,True,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.2,3,0.5,47,13.2,0.0,0.3,0.1,8,0.5,39,26.4,False,0,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,27,20,COAD:validation|OV:TCGA|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.01740577419086447,0.01740577419086447,0.0,0.0074054272890867285,0.31509773498139443,0.3076923076923077,0.019003055767761647,0.22488540870893817,0.20588235294117652
TBC1D3I,ENSG00000274933,6.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,True,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.8,3,0.9,47,6.8,0.2,0.1,0.3,8,0.9,39,7.555555555555555,False,0,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,26,20,COAD:validation|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.023086591494833678,0.023086591494833678,0.0,0.023360970511948832,0.33105327820425656,0.3076923076923077,0.09202703842883753,0.29790939137001404,0.20588235294117652
SPMAP1,ENSG00000275489,18.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,18.9,3,0.2,47,18.9,0.0,0.0,0.1,8,0.2,39,94.49999999999999,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,True,28,20,BRCA:validation|TGCT:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005901766647252961,0.005901766647252961,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0031512605042016803,0.20903361344537819,0.20588235294117652
FAM236A,ENSG00000275520,150.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,150.9,3,1.9,47,150.9,0.1,0.0,0.6,8,1.9,39,79.42105263157896,False,0,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,26,0,COAD:validation|LUAD:validation|LUSC:validation|PRAD:TCGA|READ:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.022507122507122508,0.022507122507122508,0.0,0.025905914144003964,0.33359822183631166,0.3076923076923077,0.06878992703800887,0.2746722799791854,0.20588235294117652
TBC1D3F,ENSG00000275954,6.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.6,3,0.6,47,6.6,0.2,0.0,0.5,8,0.6,39,11.0,False,0,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_testis_biased,True,False,27,0,LIHC:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.015610881476497165,0.015610881476497165,0.0,0.009966236830329904,0.3176585445226376,0.3076923076923077,0.04893390922802687,0.2548162621692034,0.20588235294117652
SPATA31A3,ENSG00000275969,4.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.6,3,0.0,47,4.6,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,False,False,26,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
SPATA31A5,ENSG00000276581,1.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.0,3,0.0,47,1.0,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_CT|daSilva2017_testis_biased,False,False,26,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
GOLGA6L6,ENSG00000277322,5.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.0,3,0.0,47,5.0,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,False,True,28,20,,melanoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
H2AB3,ENSG00000277745,30.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,30.5,3,1.4,47,30.5,0.6,0.0,0.9,8,1.4,39,21.78571428571429,False,0,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_testis_biased,True,False,26,0,CESC:TCGA|KIRP:TCGA|OV:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.036288412874471494,0.036288412874471494,0.0,0.02042648212003051,0.3281187898123382,0.3076923076923077,0.09035470071275697,0.2962370536539335,0.20588235294117652
H2AB2,ENSG00000277858,4.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; No source-backed cancer/reproductive candidate nomination,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.7,3,0.5,47,4.7,0.2,0.0,0.5,8,0.5,39,9.4,False,0,0,,,,True,False,26,0,CESC:TCGA|KIRP:TCGA|OV:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.019347144798513467,0.019347144798513467,0.0,0.012368206445414273,0.32006051413772196,0.3076923076923077,0.06418842240453493,0.27007077534571144,0.20588235294117652
GOLGA6L22,ENSG00000277865,8.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.2,3,0.1,47,8.2,0.0,0.0,0.0,8,0.1,39,81.99999999999999,False,0,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_testis_biased,False,True,26,20,,melanoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0003501400560224089,0.20623249299719892,0.20588235294117652
RDM1,ENSG00000278023,11.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,True,True,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11.5,3,2.3,47,11.5,0.1,0.4,0.5,8,2.3,39,5.0,False,0,0,,,,True,False,28,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|KICH:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06411316958996773,0.06411316958996773,0.0,0.03454298588190733,0.34223529357421506,0.3076923076923077,0.06372750298471261,0.26960985592588915,0.20588235294117652
CT45A8,ENSG00000278085,1.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,False,False,False,False,False,False,Neither,Unassessed,The declared measurement panel or reference coverage is incomplete,The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Unassessed,The declared measurement panel or reference coverage is incomplete,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.0,3,0.1,47,1.0,0.0,0.0,0.0,8,0.1,39,10.0,False,1,0,Cancer-germline,10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Loriot2025_S1|daSilva2017_testis_biased,True,True,26,20,LUSC:TCGA|LUSC:validation|OV:TCGA,ovarian cancer|stomach cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0007002801120448178,0.20658263305322133,0.20588235294117652
P3R3URF-PIK3R3,ENSG00000278139,20.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,20.9,3,0.8,47,20.9,0.0,0.0,0.0,8,0.8,39,26.124999999999996,False,0,0,,,,True,True,26,20,LUSC:validation,carcinoid|endometrial cancer|head and neck cancer|lung cancer|lymphoma|melanoma|ovarian cancer|prostate cancer|renal cancer|skin cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.007692307692307693,0.007692307692307693,0.0,0.006068726355611602,0.31376103404791933,0.3076923076923077,0.009423334551211788,0.2153056874923883,0.20588235294117652
POTEB3,ENSG00000278522,4.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.9,3,0.2,47,4.9,0.0,0.1,0.1,8,0.2,39,24.5,False,0,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_testis_biased,True,False,26,0,COAD:validation|LUSC:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009823335274703943,0.009823335274703943,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0042016806722689065,0.2100840336134454,0.20588235294117652
,ENSG00000278646,2.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,False,False,True,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Uncurated,No source-backed cancer/reproductive candidate nomination,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.2,3,0.3,47,2.2,0.0,0.0,0.0,8,0.3,39,7.333333333333334,False,0,0,,,,True,False,26,20,LIHC:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.007672634271099744,0.21355498721227625,0.20588235294117652
,ENSG00000281613,4.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,False,False,True,False,False,Neither,Antibody,Uncertain normal antibody evidence requires review,Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; No source-backed cancer/reproductive candidate nomination,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Antibody,Uncertain normal antibody evidence requires review,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.5,3,0.0,47,4.5,0.0,0.3,0.0,8,0.0,39,,True,0,0,,,,True,True,26,20,KIRC:validation,glioma|ovarian cancer|prostate cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Antibody concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TEX13D,ENSG00000282419,1.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.7,3,0.0,47,1.7,0.0,0.0,0.0,8,0.0,39,,True,0,0,Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_reproductive_PC,True,False,26,0,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TEX13C,ENSG00000282815,1.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Low,Insufficient reproductive RNA/protein or reviewed affirmative support for admission,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.6,3,0.0,47,1.6,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734,Carter2023_CT|Gong2021_reproductive_PC|Loriot2025_S1,True,False,26,0,BLCA:TCGA|LIHC:TCGA|SKCM:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
LITAFD,ENSG00000283516,6.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.9,3,0.3,47,6.9,0.0,0.0,0.1,8,0.3,39,23.000000000000004,False,0,0,Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_reproductive_PC,True,False,26,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|KICH:TCGA|KIRC:TCGA|KIRP:TCGA|LUAD:TCGA|LUSC:TCGA|PAAD:TCGA|PRAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.013020227853987444,0.21890258079516395,0.20588235294117652
,ENSG00000283599,8.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,True,False,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Cellular,Normal-cell RNA crosses a source-specific review trigger,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.0,3,0.2,47,8.0,0.0,0.0,0.0,8,0.2,39,40.0,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935,Carter2023_CT|Gong2021_reproductive_PC,True,False,26,0,BLCA:TCGA|HNSC:TCGA|LIHC:TCGA|LUSC:TCGA|READ:TCGA|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Cell RNA concern,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0013687293099057802,0.2072510822510823,0.20588235294117652
HSFX3,ENSG00000283697,14.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,False,False,False,False,False,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,False,oncoref.cta-research-selection.2026-10-26.1,Neither,Selectivity,The pinned restriction/selectivity screen does not pass,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,14.0,3,1.2,47,14.0,0.0,0.0,0.1,8,1.2,39,11.666666666666668,False,0,0,Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_reproductive_PC,True,False,26,0,PRAD:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005825242718446602,0.005825242718446602,0.0,0.0,0.3076923076923077,0.3076923076923077,0.04348241272793702,0.24936476566911353,0.20588235294117652
FIRRM,ENSG00000000460,10.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.0,3,13.0,47,10.0,2.1,3.2,2.8,8,13.0,39,0.7692307692307693,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.24542733031652436,0.24542733031652436,0.0,0.2371020008672094,0.544794308559517,0.3076923076923077,0.3511801424706568,0.5570624954118333,0.20588235294117652
SLC22A16,ENSG00000004809,20.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,20.8,3,20.2,47,20.8,0.1,0.5,0.8,8,20.2,39,1.0297029702970297,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,True,31,20,BRCA:validation|KIRC:validation|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PRAD:TCGA|UCEC:TCGA,carcinoid|colorectal cancer|endometrial cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03875782169062954,0.03875782169062954,0.0,0.03312489437214805,0.34081720206445576,0.3076923076923077,0.09522657476621671,0.3011089277073932,0.20588235294117652
ZMYND10,ENSG00000004838,251.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,251.3,3,116.2,47,251.3,0.5,0.1,116.2,8,82.5,39,2.162650602409639,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06670209105931797,0.06670209105931797,0.0,0.04739943205041037,0.35509173974271807,0.3076923076923077,0.3090889225294212,0.5149712754705977,0.20588235294117652
REXO5,ENSG00000005189,333.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,333.9,3,38.6,47,333.9,1.8,1.4,5.1,8,38.6,39,8.650259067357512,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer|liver cancer|pancreatic cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1888487107701748,0.1888487107701748,0.0,0.23768706198233133,0.5453793696746391,0.3076923076923077,0.3674664713129119,0.5733488242540884,0.20588235294117652
KRT33A,ENSG00000006059,2.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.4,3,46.0,47,2.4,0.0,0.0,0.2,8,46.0,39,0.05217391304347826,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|LUSC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1775866670224974,0.1775866670224974,0.0,0.015950604579367124,0.32364291227167485,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
DBF4,ENSG00000006634,14.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,14.7,3,0.6,47,14.7,0.2,0.1,0.3,8,0.6,39,24.5,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.028873006801127296,0.028873006801127296,0.0,0.0184054646894821,0.32609777238178983,0.3076923076923077,0.05604678782428142,0.2619291407654579,0.20588235294117652
PRSS21,ENSG00000007038,82.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,82.3,3,19.9,47,82.3,0.1,0.0,3.7,8,19.9,39,4.135678391959799,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|HNSC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06737360836734078,0.06737360836734078,0.0,0.1258156113895025,0.4335079190818102,0.3076923076923077,0.1416825664294486,0.3475649193706251,0.20588235294117652
ST7L,ENSG00000007341,35.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,35.0,3,7.4,47,35.0,5.0,3.7,5.0,8,7.4,39,4.72972972972973,False,0,0,,,,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.3050838302653185,0.3050838302653185,0.0,0.2498717394719025,0.5575640471642103,0.3076923076923077,0.5040548769367584,0.709937229877935,0.20588235294117652
TKTL1,ENSG00000007350,123.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,123.4,3,3.7,47,123.4,1.9,0.3,0.3,8,3.7,39,33.351351351351354,False,6,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BLCA:TCGA|CESC:TCGA|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:validation|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,lung cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.032503429207539965,0.032503429207539965,0.0,0.011985886118925211,0.3196781938112329,0.3076923076923077,0.1499234439843795,0.35580579692555603,0.20588235294117652
PHF7,ENSG00000010318,1181.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1181.3,3,5.5,47,1181.3,1.4,1.9,4.8,8,5.5,39,214.78181818181818,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer|endometrial cancer|pancreatic cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.25666298259833087,0.25666298259833087,0.0,0.224726079581544,0.5324183872738517,0.3076923076923077,0.4135613934911925,0.619443746432369,0.20588235294117652
ZBTB32,ENSG00000011590,47.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,47.7,3,3.3,47,47.7,0.0,0.0,0.2,8,3.3,39,14.454545454545457,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|HNSC:TCGA|KIRC:validation|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|PAAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA,lymphoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.053035678047693824,0.053035678047693824,0.0,0.050198035838519096,0.3578903435308268,0.3076923076923077,0.05846824389023877,0.26435059683141526,0.20588235294117652
TACC3,ENSG00000013810,49.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,49.1,3,55.5,47,49.1,3.4,7.7,5.2,8,55.5,39,0.8846846846846848,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.4719247003705314,0.4719247003705314,0.0,0.358470007476643,0.6661623151689506,0.3076923076923077,0.49323832650286303,0.6991206794440395,0.20588235294117652
HGF,ENSG00000019991,301.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,301.5,3,29.4,47,2.3,1.8,301.5,7.9,8,29.4,39,10.255102040816327,False,0,0,,,,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2778747231395596,0.2778747231395596,0.0,0.25231505951432576,0.5600073672066335,0.3076923076923077,0.5314021681694265,0.737284521110603,0.20588235294117652
DEPDC1,ENSG00000024526,7.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,True,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.8,3,7.9,47,7.8,1.0,3.1,2.0,8,7.9,39,0.9873417721518987,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.13362573381602727,0.13362573381602727,0.0,0.13888318015012296,0.4465754878424307,0.3076923076923077,0.11888063785448862,0.3247629907956651,0.20588235294117652
DEPDC1B,ENSG00000035499,12.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,12.3,3,20.3,47,12.3,0.7,7.3,1.1,8,20.3,39,0.6059113300492611,False,2,1,Cancer-germline|Cancer-placental,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2|10.1038/s41467-020-19141-w,Bradley2020_CPA|Bruggeman2018_GC|Jamin2021_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,endometrial cancer|liver cancer|lung cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2204489384391766,0.2204489384391766,0.0,0.16506114587197168,0.4727534535642794,0.3076923076923077,0.20766399906347507,0.4135463520046516,0.20588235294117652
SPATA7,ENSG00000042317,55.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,55.3,3,12.3,47,55.3,12.9,2.7,8.1,8,12.3,39,4.495934959349593,False,0,0,,,,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.34783258662623,0.34783258662623,0.0,0.2800575034764077,0.5877498111687154,0.3076923076923077,0.5734584177859592,0.7793407707271357,0.20588235294117652
ZPBP,ENSG00000042813,138.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,138.9,3,4.5,47,138.9,0.2,0.0,0.7,8,4.5,39,30.866666666666667,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,31,20,,glioma|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005825242718446602,0.005825242718446602,0.0,0.0,0.3076923076923077,0.3076923076923077,0.025709584533113946,0.23159193747429047,0.20588235294117652
DCUN1D1,ENSG00000043093,239.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,239.3,3,36.7,47,239.3,12.0,12.2,13.4,8,36.7,39,6.520435967302452,False,0,0,,,,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|colorectal cancer|liver cancer|melanoma|pancreatic cancer|prostate cancer|renal cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.5841579793749815,0.5841579793749815,0.0,0.48805523477887847,0.7957475424711862,0.3076923076923077,0.6923830939679303,0.8982654469091068,0.20588235294117652
GUCA1A,ENSG00000048545,8.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.4,3,734.2,47,8.4,0.1,0.0,0.0,8,734.2,39,0.011441024244075183,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:validation|COAD:validation|GBM:TCGA|GBM:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|PAAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.048318919023142455,0.25420127196431896,0.20588235294117652
ERCC8,ENSG00000049167,4.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.0,3,4.0,47,4.0,3.8,3.1,4.0,8,4.0,39,1.0,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.23967091613066663,0.23967091613066663,0.0,0.2310603801796672,0.538752687871975,0.3076923076923077,0.4714065429309844,0.6772888958721609,0.20588235294117652
RAD51,ENSG00000051180,23.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,23.5,3,15.2,47,23.5,2.0,6.6,1.9,8,15.2,39,1.5460526315789473,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.23202165695737767,0.23202165695737767,0.0,0.22730719054993584,0.5349994982422436,0.3076923076923077,0.264144748561177,0.4700271015023535,0.20588235294117652
MSH4,ENSG00000057468,4.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.1,3,1.8,47,4.1,0.4,0.1,1.8,8,1.0,39,2.2777777777777777,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:validation|COAD:validation|GBM:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.019347144798513467,0.019347144798513467,0.0,0.013631177565603796,0.3213234852579115,0.3076923076923077,0.0674301425580198,0.27331249549919634,0.20588235294117652
SLC6A16,ENSG00000063127,91.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,91.4,3,15.5,47,91.4,6.8,3.0,5.6,8,15.5,39,5.896774193548388,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2426129505857899,0.2426129505857899,0.0,0.18278987061236524,0.49048217830467294,0.3076923076923077,0.4552102697706188,0.6610926227117953,0.20588235294117652
AHRR,ENSG00000063438,45.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,45.1,3,5.8,47,45.1,2.6,1.9,3.7,8,5.8,39,7.775862068965518,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.19670441500760416,0.19670441500760416,0.0,0.10324744099090644,0.41093974868321415,0.3076923076923077,0.2190358166056566,0.42491816954683315,0.20588235294117652
SPA17,ENSG00000064199,224.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,True,True,True,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal RNA exceeds its applicable local category/IHC ceiling; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,224.8,3,23.7,47,224.8,1.6,0.8,23.7,8,16.1,39,9.48523206751055,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.24886119161420814,0.24886119161420814,0.0,0.22726721827321034,0.534959525965518,0.3076923076923077,0.5051196648614356,0.7110020178026121,0.20588235294117652
DDX20,ENSG00000064703,51.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,51.3,3,8.5,47,51.3,4.2,2.3,4.7,8,8.5,39,6.035294117647059,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer|skin cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2771779619396529,0.2771779619396529,0.0,0.22503447763079942,0.5327267853231071,0.3076923076923077,0.4593151216336066,0.6651974745747831,0.20588235294117652
ROPN1,ENSG00000065371,154.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,154.4,3,20.2,47,154.4,0.0,0.0,20.2,8,6.0,39,7.643564356435644,False,6,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:TCGA|BRCA:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|LUSC:TCGA|SKCM:TCGA,colorectal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.026086956521739132,0.026086956521739132,0.0,0.05029585798816569,0.3579881656804734,0.3076923076923077,0.037018820906288934,0.24290117384746546,0.20588235294117652
ZMYND12,ENSG00000066185,27.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,27.9,3,16.5,47,27.9,2.3,0.4,16.5,8,9.9,39,1.690909090909091,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1239653113810868,0.1239653113810868,0.0,0.1121387240342348,0.4198310317265425,0.3076923076923077,0.4059738527015203,0.6118562056426968,0.20588235294117652
STAG3,ENSG00000066923,51.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,51.7,3,1.1,47,51.7,0.3,0.3,0.3,8,1.1,39,47.0,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03088449718946578,0.03088449718946578,0.0,0.021907924175243055,0.3296002318675508,0.3076923076923077,0.11088016777362569,0.3167625207148022,0.20588235294117652
SDK2,ENSG00000069188,9.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.4,3,5.3,47,9.4,0.7,0.3,5.3,8,2.6,39,1.7735849056603774,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.08886681052050761,0.08886681052050761,0.0,0.06098098499707149,0.3686732926893792,0.3076923076923077,0.18699628860626866,0.3928786415474452,0.20588235294117652
FRMPD1,ENSG00000070601,9.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.1,3,66.8,47,9.1,0.2,0.4,0.9,8,66.8,39,0.13622754491017963,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1132643997094125,0.1132643997094125,0.0,0.10300931406289315,0.41070162175520086,0.3076923076923077,0.26388271282378345,0.46976506576495997,0.20588235294117652
EPHA8,ENSG00000070886,2.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.1,3,32.4,47,2.1,0.0,0.0,0.0,8,32.4,39,0.06481481481481483,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BRCA:TCGA|BRCA:validation|CESC:TCGA|HNSC:TCGA|LUSC:TCGA|PAAD:TCGA|PAAD:validation|PRAD:TCGA|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|liver cancer|melanoma|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06404916353704337,0.06404916353704337,0.0,0.0,0.3076923076923077,0.3076923076923077,0.15863437039433667,0.3645167233355132,0.20588235294117652
TRIP13,ENSG00000071539,29.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,29.0,3,9.0,47,29.0,3.2,3.2,6.5,8,9.0,39,3.2222222222222223,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,prostate cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.19660064827957835,0.19660064827957835,0.0,0.19238614170061752,0.5000784493929252,0.3076923076923077,0.29760450644932374,0.5034868593905002,0.20588235294117652
HMMR,ENSG00000072571,26.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,26.7,3,26.5,47,26.7,1.6,6.0,2.0,8,26.5,39,1.0075471698113208,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.27501043478519666,0.27501043478519666,0.0,0.24441838529256735,0.552110692984875,0.3076923076923077,0.2917672881183032,0.49764964105947973,0.20588235294117652
FCGR2B,ENSG00000072694,389.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,389.2,3,41.3,47,2.5,4.1,389.2,15.1,8,41.3,39,9.423728813559322,False,0,0,,,,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.499312768205324,0.499312768205324,0.0,0.41421717917773565,0.7219094868700433,0.3076923076923077,0.5504083128513981,0.7562906657925746,0.20588235294117652
TIPIN,ENSG00000075131,19.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,19.9,3,12.5,47,19.9,6.3,3.6,5.7,8,12.5,39,1.5919999999999999,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.31165999388505783,0.31165999388505783,0.0,0.30173911986393465,0.6094314275562424,0.3076923076923077,0.5354802068451695,0.741362559786346,0.20588235294117652
WDR62,ENSG00000075702,61.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,61.9,3,106.5,47,61.9,0.3,0.5,1.3,8,106.5,39,0.5812206572769953,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1534520946285652,0.1534520946285652,0.0,0.16800469102569163,0.4756969987179993,0.3076923076923077,0.29715511695795643,0.5030374698991329,0.20588235294117652
TUBA3D,ENSG00000075886,214.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,214.1,3,83.4,47,214.1,0.5,0.0,9.8,8,83.4,39,2.5671462829736207,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,True,31,20,BRCA:TCGA|BRCA:validation|COAD:validation|KIRC:TCGA|KIRC:validation|LIHC:TCGA|OV:TCGA|OV:validation|PRAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|colorectal cancer|endometrial cancer|glioma|head and neck cancer|melanoma|prostate cancer|skin cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.023047764082680697,0.023047764082680697,0.0,0.015955543222862103,0.3236478509151698,0.3076923076923077,0.12300972735146726,0.3288920802926438,0.20588235294117652
CAPN6,ENSG00000077274,207.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,80.4,3,207.7,47,1.9,6.2,80.4,207.7,8,13.7,39,0.38709677419354843,False,0,1,Cancer-placental|Cancer-reproductive,10.1038/s41467-020-19141-w|10.1038/s41467-021-22695-y,Bradley2020_CPA|Gong2021_placenta_PC|Gong2021_reproductive_PC,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,False,True,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.13550235495906263,0.13550235495906263,0.0,0.30771591972745427,0.615408227419762,0.3076923076923077,0.23718518778803763,0.44306754072921417,0.20588235294117652
SPAG6,ENSG00000077327,93.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,93.5,3,96.8,47,93.5,0.1,0.0,47.4,8,96.8,39,0.9659090909090909,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|GBM:validation|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.015497748430556275,0.015497748430556275,0.0,0.01824405103093628,0.325936358723244,0.3076923076923077,0.21741191727460063,0.42329427021577715,0.20588235294117652
PIAS2,ENSG00000078043,65.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,65.3,3,15.6,47,65.3,4.8,3.8,7.3,8,15.6,39,4.185897435897436,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|colorectal cancer|glioma|head and neck cancer|liver cancer|lung cancer|melanoma|renal cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.373378625420778,0.373378625420778,0.0,0.3394639528113964,0.6471562605037041,0.3076923076923077,0.5891747601180735,0.79505711305925,0.20588235294117652
NEBL,ENSG00000078114,12.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.6,3,301.0,47,2.7,1.1,3.6,12.5,8,301.0,39,0.011960132890365448,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.18632/oncotarget.21715,Jamin2021_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|liver cancer|lung cancer|melanoma|pancreatic cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.305738419278353,0.305738419278353,0.0,0.202115701501362,0.5098080091936696,0.3076923076923077,0.4843449541258897,0.6902273070670661,0.20588235294117652
ZCWPW1,ENSG00000078487,41.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,41.3,3,5.7,47,41.3,5.3,1.8,4.6,8,5.7,39,7.245614035087718,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.27622772884642616,0.27622772884642616,0.0,0.22985028801041127,0.537542595702719,0.3076923076923077,0.4786774975361886,0.6845598504773651,0.20588235294117652
PKD2L2,ENSG00000078795,7.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.9,3,2.2,47,7.9,0.2,0.2,0.7,8,2.2,39,3.590909090909091,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.043601182102433036,0.043601182102433036,0.0,0.03529269220251388,0.34298499989482156,0.3076923076923077,0.1585485891105963,0.36443094205177284,0.20588235294117652
DDX43,ENSG00000080007,19.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,19.0,3,1.8,47,19.0,1.1,4.7,1.7,8,1.8,39,10.555555555555555,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,liver cancer|renal cancer|testis cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.08124011984749907,0.08124011984749907,0.0,0.08340729970041606,0.39109960739272376,0.3076923076923077,0.18031746836094664,0.38619982130212316,0.20588235294117652
EPHA6,ENSG00000080224,8.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.0,3,3.1,47,8.0,3.9,0.0,1.8,8,3.1,39,2.5806451612903225,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|ovarian cancer|prostate cancer|stomach cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04175610838394764,0.04175610838394764,0.0,0.06672208468851741,0.37441439238082513,0.3076923076923077,0.0988495621653884,0.30473191510656494,0.20588235294117652
DNAAF6,ENSG00000080572,11.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11.6,3,10.5,47,11.6,0.0,0.0,10.5,8,3.9,39,1.1047619047619048,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,29,20,CESC:TCGA|GBM:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:validation|SKCM:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.0,0.3076923076923077,0.3076923076923077,0.04373452638055381,0.24961687932173032,0.20588235294117652
AFP,ENSG00000081051,0.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; No source-backed cancer/reproductive candidate nomination,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.1,3,3.6,47,0.0,0.1,0.0,0.3,8,3.6,39,0.02777777777777778,False,0,0,,,,True,True,31,20,BRCA:TCGA|BRCA:validation|GBM:validation|LIHC:TCGA|LIHC:validation|STAD:TCGA|TGCT:TCGA,cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,Oncofetal,Membership support,Reviewed reproductive/developmental and tumor association supports biological membership; not a safety or approval claim.,https://pubmed.ncbi.nlm.nih.gov/6182184/|https://pubmed.ncbi.nlm.nih.gov/10397256/,AFP is secreted; antigen expression does not imply an accessible cell-surface target or tumor-restricted peptide presentation.,Locus,True,True,False,False,False,False,Established,Oncofetal,Reviewed reproductive/developmental and tumor association,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.04061624649859944,0.24649859943977595,0.20588235294117652
EPYC,ENSG00000083782,6.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.2,3,0.8,47,0.1,0.4,6.2,0.8,8,0.3,39,7.75,False,0,0,,,,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|HNSC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.003663003663003663,0.31135531135531136,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
AGBL5,ENSG00000084693,187.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,187.3,3,48.3,47,187.3,14.2,10.8,25.4,8,48.3,39,3.8778467908902696,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.5829809695201471,0.5829809695201471,0.0,0.48380888885255063,0.7915011965448584,0.3076923076923077,0.6693678427740011,0.8752501957151776,0.20588235294117652
NME8,ENSG00000086288,10.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.1,3,12.2,47,10.1,0.0,0.2,0.1,8,12.2,39,0.8278688524590164,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,False,29,20,GBM:validation|KIRC:validation|LUAD:validation|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03367956661237446,0.03367956661237446,0.0,0.017144430641562805,0.3248367383338705,0.3076923076923077,0.08692541203978112,0.2928077649809576,0.20588235294117652
PPEF1,ENSG00000086717,13.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.6,3,10.3,47,13.6,0.2,0.7,4.1,8,10.3,39,1.320388349514563,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1371/journal.pgen.1011734,Chang2019_TGCT|Jamin2021_CT|Loriot2025_S2|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|TGCT:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02132734281831545,0.02132734281831545,0.0,0.009966236830329904,0.3176585445226376,0.3076923076923077,0.15009603197800805,0.35597838491918454,0.20588235294117652
AURKA,ENSG00000087586,29.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,29.9,3,21.4,47,29.9,8.2,7.8,2.5,8,21.4,39,1.397196261682243,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer|lymphoma|ovarian cancer|stomach cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.29562386057202483,0.29562386057202483,0.0,0.3404728751561119,0.6481651828484196,0.3076923076923077,0.46738757262008424,0.6732699255612608,0.20588235294117652
TPX2,ENSG00000088325,29.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,29.8,3,68.5,47,29.8,2.8,8.0,4.0,8,68.5,39,0.43503649635036495,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.3884776801184058,0.3884776801184058,0.0,0.31753061121209286,0.6252229189044005,0.3076923076923077,0.345322389978917,0.5512047429200935,0.20588235294117652
ARHGAP28,ENSG00000088756,75.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,75.1,3,12.3,47,75.1,7.9,25.0,8.5,8,12.3,39,6.105691056910568,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.3044255318489078,0.3044255318489078,0.0,0.1780679096889693,0.485760217381277,0.3076923076923077,0.3631109063378819,0.5689932592790584,0.20588235294117652
CMTM1,ENSG00000089505,30.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,30.4,3,3.1,47,30.4,1.9,1.2,1.5,8,3.1,39,9.806451612903224,False,5,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Jamin2021_core|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,ovarian cancer|prostate cancer|renal cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.13980742666224844,0.13980742666224844,0.0,0.09464653214152974,0.40233883983383745,0.3076923076923077,0.21841092396858902,0.42429327690976554,0.20588235294117652
ORC6,ENSG00000091651,9.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.3,3,10.1,47,9.3,1.0,3.2,1.2,8,10.1,39,0.9207920792079209,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,30,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.14573574421431396,0.14573574421431396,0.0,0.14572918543366833,0.453421493125976,0.3076923076923077,0.24126603785836429,0.44714839079954083,0.20588235294117652
RPGRIP1,ENSG00000092200,57.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,57.6,3,179.2,47,57.6,0.0,1.1,0.6,8,179.2,39,0.32142857142857145,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|COAD:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.036364936803277854,0.036364936803277854,0.0,0.026835482142503257,0.33452778983481096,0.3076923076923077,0.11417891529043102,0.3200612682316075,0.20588235294117652
CLSPN,ENSG00000092853,5.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.6,3,11.1,47,5.6,0.3,1.4,0.7,8,11.1,39,0.5045045045045045,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1416994191171659,0.1416994191171659,0.0,0.09815643827683389,0.4058487459691416,0.3076923076923077,0.1617423006069813,0.3676246535481578,0.20588235294117652
CDC45,ENSG00000093009,22.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,22.7,3,25.1,47,22.7,1.2,3.1,1.6,8,25.1,39,0.9043824701195219,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|lung cancer|melanoma|prostate cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2404698067673731,0.2404698067673731,0.0,0.20969199554421675,0.5173843032365244,0.3076923076923077,0.2012533067676016,0.4071356597087781,0.20588235294117652
MYO3A,ENSG00000095777,5.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.0,3,15.0,47,5.0,0.0,0.0,0.3,8,15.0,39,0.3333333333333333,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA,colorectal cancer|lung cancer|lymphoma|melanoma|renal cancer|skin cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02290744742423665,0.02290744742423665,0.0,0.011068430952090392,0.3187607386443981,0.3076923076923077,0.07588711992776351,0.28176947286894005,0.20588235294117652
CATSPERG,ENSG00000099338,30.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,30.5,3,2.4,47,30.5,0.3,0.1,0.7,8,2.4,39,12.708333333333334,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|COAD:validation|GBM:TCGA|GBM:validation|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|OV:TCGA|OV:validation|PAAD:validation|PRAD:TCGA|READ:validation|TGCT:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.037802276874052375,0.037802276874052375,0.0,0.019812375179905587,0.3275046828722133,0.3076923076923077,0.08704525440458943,0.29292760734576595,0.20588235294117652
MAGEB2,ENSG00000099399,28.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,28.2,3,0.1,47,28.2,0.4,0.4,0.0,8,0.1,39,282.0,False,7,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Jamin2021_core|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|PAAD:validation|READ:TCGA|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
IZUMO4,ENSG00000099840,430.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,430.8,3,17.8,47,430.8,6.3,0.3,7.3,8,17.8,39,24.202247191011235,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,30,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,carcinoid|colorectal cancer|glioma|head and neck cancer|melanoma|skin cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.19871757411203417,0.19871757411203417,0.0,0.16871370540546346,0.4764060130977712,0.3076923076923077,0.4806167630907413,0.6864991160319178,0.20588235294117652
MMP11,ENSG00000099953,138.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,38.3,3,138.5,47,6.5,15.8,38.3,138.5,8,9.1,39,0.27653429602888085,False,0,1,Cancer-placental|Cancer-reproductive,10.1038/s41467-020-19141-w|10.1038/s41467-021-22695-y,Bradley2020_CPA|Gong2021_placenta_PC|Gong2021_reproductive_PC,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,carcinoid|colorectal cancer|liver cancer|melanoma|prostate cancer|renal cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,False,True,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1958453904148479,0.1958453904148479,0.0,0.21623565205604867,0.5239279597483564,0.3076923076923077,0.3154070017930199,0.5212893547341964,0.20588235294117652
YPEL1,ENSG00000100027,75.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,75.4,3,25.3,47,75.4,7.0,1.2,3.9,8,25.3,39,2.9802371541501977,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.32480615866195806,0.32480615866195806,0.0,0.23534447872076303,0.5430367864130707,0.3076923076923077,0.5202781667373305,0.726160519678507,0.20588235294117652
GGTLC2,ENSG00000100121,24.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,24.1,3,4.8,47,24.1,0.0,0.4,0.6,8,4.8,39,5.020833333333334,False,2,0,Cancer-germline|Cancer-reproductive,10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734,Bruggeman2018_GC|Gong2021_reproductive_PC|Loriot2025_S2,True,True,31,20,BRCA:validation|COAD:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|READ:validation|THCA:TCGA|UCEC:TCGA,liver cancer|prostate cancer|renal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.12242525505022485,0.12242525505022485,0.0,0.04672455708740947,0.3544168647797172,0.3076923076923077,0.12311432696188136,0.32899667990305786,0.20588235294117652
DMC1,ENSG00000100206,11.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11.5,3,3.2,47,11.5,0.8,0.6,2.3,8,3.2,39,3.59375,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0977442404629118,0.0977442404629118,0.0,0.07748467192381998,0.3851769796161277,0.3076923076923077,0.18942231160901238,0.39530466455018887,0.20588235294117652
CDKN3,ENSG00000100526,199.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,199.9,3,42.3,47,199.9,5.1,6.4,4.0,8,42.3,39,4.725768321513002,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.36640897526212823,0.36640897526212823,0.0,0.3553876137515479,0.6630799214438556,0.3076923076923077,0.4724620740698283,0.6783444270110048,0.20588235294117652
SAMD15,ENSG00000100583,15.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.6,3,14.5,47,15.6,0.4,0.3,5.2,8,14.5,39,1.0758620689655172,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,30,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.08173560686410487,0.08173560686410487,0.0,0.06201530046292397,0.3697076081552317,0.3076923076923077,0.2153859435430724,0.4212682964842489,0.20588235294117652
ISM2,ENSG00000100593,206.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,206.2,3,3.6,47,1.5,0.1,206.2,3.6,8,2.1,39,57.27777777777777,False,0,0,Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_placenta_PC|Gong2021_reproductive_PC,True,True,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,colorectal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013300952736783113,0.013300952736783113,0.0,0.014694509174942808,0.3223868168672505,0.3076923076923077,0.06098508912587884,0.26686744206705537,0.20588235294117652
CEP128,ENSG00000100629,5.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.0,3,24.2,47,5.0,1.4,1.0,3.7,8,24.2,39,0.2066115702479339,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,True,30,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.277236756033622,0.277236756033622,0.0,0.16431388790288526,0.47200619559519297,0.3076923076923077,0.29824548836955767,0.5041278413107342,0.20588235294117652
GINS1,ENSG00000101003,8.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.8,3,7.1,47,8.8,1.3,3.0,1.5,8,7.1,39,1.23943661971831,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,cervical cancer|colorectal cancer|glioma|head and neck cancer|lymphoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1844841773697989,0.1844841773697989,0.0,0.1664882261958442,0.4741805338881519,0.3076923076923077,0.24289683472743048,0.448779187668607,0.20588235294117652
MYBL2,ENSG00000101057,15.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.1,3,90.6,47,15.1,2.5,5.6,2.4,8,90.6,39,0.16666666666666669,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.39433279260818577,0.39433279260818577,0.0,0.2848044550475793,0.5924967627398869,0.3076923076923077,0.28366185569994923,0.48954420864112574,0.20588235294117652
SLC52A3,ENSG00000101276,39.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,39.3,3,18.6,47,39.3,1.5,4.1,7.7,8,18.6,39,2.1129032258064515,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|prostate cancer|skin cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.08655366845721763,0.08655366845721763,0.0,0.250745536318118,0.5584378440104257,0.3076923076923077,0.34532808715343793,0.5512104400946145,0.20588235294117652
MROH8,ENSG00000101353,18.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,18.1,3,5.6,47,18.1,1.5,0.9,3.4,8,5.6,39,3.2321428571428577,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,renal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.11249965917217075,0.11249965917217075,0.0,0.12120397092465962,0.42889627861696733,0.3076923076923077,0.33016272186605106,0.5360450748072276,0.20588235294117652
EPPIN,ENSG00000101448,319.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,81.9,3,319.7,47,81.9,0.1,0.1,319.7,8,2.3,39,0.25617766656240226,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:validation|KICH:TCGA|KIRC:TCGA|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.030451058928244196,0.030451058928244196,0.0,0.020722557012879596,0.3284148647051873,0.3076923076923077,0.1041604108204358,0.3100427637616123,0.20588235294117652
RHOXF1,ENSG00000101883,14.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,14.6,3,12.6,47,14.6,3.4,0.0,2.3,8,12.6,39,1.1587301587301588,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|OV:TCGA|OV:validation|PAAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09576501632991609,0.09576501632991609,0.0,0.0538429718192945,0.3615352795116022,0.3076923076923077,0.22678062037453636,0.4326629733157129,0.20588235294117652
ASB9,ENSG00000102048,25.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,25.1,3,16.9,47,25.1,1.1,3.0,2.2,8,16.9,39,1.4852071005917162,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.26394195613685134,0.26394195613685134,0.0,0.15610247659946408,0.4637947842917718,0.3076923076923077,0.35625019487630927,0.5621325478174858,0.20588235294117652
PPP1R2C,ENSG00000102055,69.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,69.0,3,0.3,47,69.0,0.0,0.0,0.0,8,0.3,39,230.0,False,0,0,Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_reproductive_PC,True,False,29,0,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.003836317135549872,0.2097186700767264,0.20588235294117652
VGLL1,ENSG00000102243,196.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,196.9,3,21.9,47,0.1,0.0,196.9,6.4,8,21.9,39,8.990867579908677,False,0,1,Cancer-placental|Cancer-reproductive,10.1038/s41467-020-19141-w|10.1038/s41467-021-22695-y,Bradley2020_CPA|Gong2021_placenta_PC|Gong2021_reproductive_PC,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|HNSC:TCGA|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,Cancer-placental,Membership support,Reviewed reproductive/developmental and tumor association supports biological membership; not a safety or approval claim.,https://pubmed.ncbi.nlm.nih.gov/33087697/,Normal somatic RNA remains a risk flag; findings for VGLL1 do not validate all genes in the source panel.,Locus,True,True,False,True,True,False,Established,Cancer-placental,Reviewed reproductive/developmental and tumor association,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.021144089991685076,0.021144089991685076,0.0,0.11977990384062491,0.42747221153293263,0.3076923076923077,0.1317933199104606,0.33767567285163713,0.20588235294117652
TAF7L,ENSG00000102387,30.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,30.7,3,3.9,47,30.7,0.1,0.3,2.4,8,3.9,39,7.871794871794871,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:validation|HNSC:TCGA|KICH:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|OV:TCGA|OV:validation|READ:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,colorectal cancer|melanoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02047415750749387,0.02047415750749387,0.0,0.042049645544511335,0.34974195323681906,0.3076923076923077,0.08205694872439673,0.28793930166557324,0.20588235294117652
FLT1,ENSG00000102755,405.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,405.3,3,48.3,47,5.9,5.1,405.3,29.4,8,48.3,39,8.391304347826088,False,0,0,,,,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,head and neck cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.5789050862810818,0.5789050862810818,0.0,0.4257056023384333,0.7333979100307411,0.3076923076923077,0.6689574290020635,0.87483978194324,0.20588235294117652
CBLN1,ENSG00000102924,31.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,31.0,3,439.8,47,31.0,1.7,0.0,5.6,8,439.8,39,0.07048658481127786,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|LIHC:TCGA|LIHC:validation|LUAD:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.16332421130732597,0.16332421130732597,0.0,0.08515943099193829,0.392851738684246,0.3076923076923077,0.33598976519593193,0.5418721181371084,0.20588235294117652
SLC6A2,ENSG00000103546,6.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.6,3,10.1,47,4.3,0.1,6.6,2.3,8,10.1,39,0.6534653465346535,False,3,0,Cancer-germline|Cancer-placental|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_placenta_PC|Gong2021_reproductive_PC|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|HNSC:TCGA|KICH:TCGA|LIHC:TCGA|LIHC:validation|LUSC:TCGA|LUSC:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,colorectal cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.07515307766677409,0.07515307766677409,0.0,0.021845155189909066,0.32953746288221675,0.3076923076923077,0.07061971392940934,0.27650206687058587,0.20588235294117652
OIP5,ENSG00000104147,20.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,20.3,3,10.2,47,20.3,2.2,2.2,1.3,8,10.2,39,1.9901960784313728,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.19017476123056215,0.19017476123056215,0.0,0.16884251900204778,0.4765348266943555,0.3076923076923077,0.28492452131135937,0.4908068742525359,0.20588235294117652
IL7,ENSG00000104432,4.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.7,3,8.5,47,1.7,0.9,0.3,4.6,8,8.5,39,0.19999999999999998,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.21494712056248638,0.21494712056248638,0.0,0.2060028602625636,0.5136951679548714,0.3076923076923077,0.2854026237317203,0.49128497667289683,0.20588235294117652
TULP2,ENSG00000104804,30.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,30.4,3,0.9,47,30.4,0.7,0.1,0.4,8,0.9,39,33.77777777777778,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,0,COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PRAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.01849395948769189,0.01849395948769189,0.0,0.012408884963089088,0.32010119265539677,0.3076923076923077,0.04469829214074738,0.2505806450819239,0.20588235294117652
IL4I1,ENSG00000104951,26.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,26.0,3,17.6,47,26.0,0.3,1.8,3.7,8,17.6,39,1.477272727272727,False,2,0,Cancer-germline,10.1038/s41388-018-0357-2|10.18632/oncotarget.21715,Bruggeman2018_GC|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,endometrial cancer|glioma|lung cancer|lymphoma|ovarian cancer|prostate cancer|skin cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.15980779204113582,0.15980779204113582,0.0,0.15039098254588476,0.4580832902381925,0.3076923076923077,0.29229956925268735,0.49818192219386387,0.20588235294117652
ASF1B,ENSG00000105011,31.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,31.1,3,22.6,47,31.1,1.3,3.5,3.1,8,22.6,39,1.3761061946902655,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.29163219284422803,0.29163219284422803,0.0,0.25449259303933114,0.5621849007316388,0.3076923076923077,0.28552116877489225,0.49140352171606877,0.20588235294117652
SLC1A6,ENSG00000105143,27.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,27.2,3,117.1,47,27.2,0.1,0.7,1.7,8,117.1,39,0.23228010247651582,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Jamin2021_core|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRP:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,melanoma|ovarian cancer|pancreatic cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.10822602548067284,0.10822602548067284,0.0,0.03091302574983857,0.3386053334421463,0.3076923076923077,0.17859489838496626,0.38447725132614274,0.20588235294117652
AURKC,ENSG00000105146,45.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,45.2,3,4.9,47,45.2,0.7,1.9,2.0,8,4.9,39,9.224489795918368,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer|liver cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|stomach cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1466305929393178,0.1466305929393178,0.0,0.10623963656023483,0.41393194425254254,0.3076923076923077,0.3257324618905293,0.5316148148317058,0.20588235294117652
EBI3,ENSG00000105246,142.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,142.7,3,33.1,47,0.9,0.9,142.7,2.3,8,33.1,39,4.311178247734138,False,0,0,Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_placenta_PC|Gong2021_reproductive_PC,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.338480890658186,0.338480890658186,0.0,0.19908324961062246,0.5067755573029302,0.3076923076923077,0.3985983257690022,0.6044806787101787,0.20588235294117652
SYNGR4,ENSG00000105467,52.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,52.9,3,6.1,47,52.9,0.0,0.0,0.2,8,6.1,39,8.672131147540984,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|OV:TCGA|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.03845309836093246,0.3461454060532402,0.3076923076923077,0.06196493174776479,0.2678472846889413,0.20588235294117652
SIGLEC6,ENSG00000105492,103.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,103.1,3,4.3,47,0.3,0.0,103.1,1.6,8,4.3,39,23.97674418604651,False,0,0,Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_placenta_PC|Gong2021_reproductive_PC,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06298850545015243,0.06298850545015243,0.0,0.15279226542855626,0.460484573120864,0.3076923076923077,0.15631108732131752,0.362193440262494,0.20588235294117652
ETV2,ENSG00000105672,18.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,18.5,3,2.3,47,18.5,0.9,0.3,1.1,8,2.3,39,8.043478260869566,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.07263113129632698,0.07263113129632698,0.0,0.08277156972967904,0.39046387742198674,0.3076923076923077,0.19096532638581695,0.3968476793269935,0.20588235294117652
GAPDHS,ENSG00000105679,262.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,262.3,3,13.5,47,262.3,1.4,1.1,2.6,8,13.5,39,19.42962962962963,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,melanoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.3090851274662003,0.3090851274662003,0.0,0.14378512690378956,0.45147743459609724,0.3076923076923077,0.2862622632546071,0.4921446161957836,0.20588235294117652
TFPI2,ENSG00000105825,925.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,925.7,3,74.1,47,0.7,30.9,925.7,31.1,8,74.1,39,12.492577597840757,False,0,0,Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_placenta_PC|Gong2021_reproductive_PC,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,endometrial cancer|lung cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.3368219641177082,0.3368219641177082,0.0,0.23292563759476215,0.5406179452870699,0.3076923076923077,0.5418805844944468,0.7477629374356233,0.20588235294117652
RNF32,ENSG00000105982,59.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,59.0,3,10.8,47,59.0,1.5,1.4,10.8,8,3.4,39,5.462962962962963,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.14818186370759337,0.14818186370759337,0.0,0.1145984256676085,0.4222907333599162,0.3076923076923077,0.3266442996218956,0.5325266525630721,0.20588235294117652
WNT2,ENSG00000105989,38.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,38.6,3,8.3,47,0.5,0.2,38.6,8.3,8,6.7,39,4.650602409638554,False,0,0,,,,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.051397891457044424,0.051397891457044424,0.0,0.014081546868432115,0.3217738545607398,0.3076923076923077,0.10414508663052797,0.3100274395717045,0.20588235294117652
ANKRD7,ENSG00000106013,834.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,834.8,3,1.9,47,834.8,0.2,0.0,1.9,8,0.8,39,439.36842105263156,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|SKCM:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.024676977501671735,0.024676977501671735,0.0,0.013790017491762601,0.32148232518407033,0.3076923076923077,0.10846171802054154,0.31434407096171807,0.20588235294117652
MEST,ENSG00000106484,745.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,745.6,3,113.7,47,25.5,31.6,745.6,61.0,8,113.7,39,6.557607739665787,False,0,0,,,,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.6329251756436192,0.6329251756436192,0.0,0.430514063142237,0.7382063708345448,0.3076923076923077,0.7020237200119178,0.9079060729530943,0.20588235294117652
TBL2,ENSG00000106638,18.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,18.8,3,15.5,47,18.8,4.0,1.7,4.0,8,15.5,39,1.2129032258064516,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2440313628563024,0.2440313628563024,0.0,0.22349940999701334,0.531191717689321,0.3076923076923077,0.4567442513895985,0.662626604330775,0.20588235294117652
GALNTL5,ENSG00000106648,10.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.5,3,1.4,47,10.5,0.0,0.0,0.0,8,1.4,39,7.500000000000001,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Jamin2021_core|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,GBM:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.008686535240645728,0.21456888818182224,0.20588235294117652
UBE2S,ENSG00000108106,153.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,153.9,3,114.3,47,153.9,14.3,13.1,17.3,8,114.3,39,1.3464566929133859,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,melanoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.6372081086657031,0.6372081086657031,0.0,0.475192400968839,0.7828847086611468,0.3076923076923077,0.7095655619335426,0.9154479148747191,0.20588235294117652
HSD17B1,ENSG00000108786,79.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,79.7,3,6.1,47,3.7,6.6,79.7,3.1,8,6.1,39,13.065573770491804,False,0,0,Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_placenta_PC|Gong2021_reproductive_PC,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.21806102349630957,0.21806102349630957,0.0,0.14300278874557523,0.45069509643788297,0.3076923076923077,0.3803061868019708,0.5861885397431473,0.20588235294117652
CRACD,ENSG00000109265,28.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,28.4,3,18.8,47,28.4,2.3,0.6,6.0,8,18.8,39,1.5106382978723403,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Jamin2021_core|Wang2016_CT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06611849874346855,0.06611849874346855,0.0,0.2016896434997375,0.5093819511920452,0.3076923076923077,0.34900767871071436,0.5548900316518909,0.20588235294117652
CPZ,ENSG00000109625,147.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,147.1,3,32.2,47,3.0,147.1,40.7,32.2,8,29.7,39,4.568322981366459,False,0,0,,,,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.35463790527815064,0.35463790527815064,0.0,0.23531086494850176,0.5430031726408094,0.3076923076923077,0.3576441523008593,0.5635265052420357,0.20588235294117652
DDX25,ENSG00000109832,88.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,88.8,3,22.0,47,88.8,1.0,0.2,0.6,8,22.0,39,4.036363636363636,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|SKCM:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.10580475860383115,0.10580475860383115,0.0,0.030929519676423295,0.33862182736873103,0.3076923076923077,0.28480173836124567,0.4906840913024222,0.20588235294117652
CCDC34,ENSG00000109881,47.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,47.4,3,21.7,47,47.4,10.3,4.9,12.1,8,21.7,39,2.184331797235023,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.38185985426409846,0.38185985426409846,0.0,0.3424988620966699,0.6501911697889776,0.3076923076923077,0.5542330044268923,0.7601153573680688,0.20588235294117652
AKAP3,ENSG00000111254,97.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,97.2,3,4.1,47,97.2,0.5,0.7,2.6,8,4.1,39,23.707317073170735,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.07449819627018808,0.07449819627018808,0.0,0.06692743249861505,0.37461974019092276,0.3076923076923077,0.2691847621318961,0.47506711507307264,0.20588235294117652
GSG1,ENSG00000111305,418.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,418.0,3,29.5,47,418.0,0.7,0.2,0.4,8,29.5,39,14.169491525423728,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:validation|GBM:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUSC:TCGA|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013783731314307903,0.013783731314307903,0.0,0.01118852943284461,0.3188808371251523,0.3076923076923077,0.15122908391942128,0.35711143686059776,0.20588235294117652
ACRBP,ENSG00000111644,275.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,275.6,3,13.9,47,275.6,0.9,2.2,13.9,8,13.4,39,19.827338129496404,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.31716060556185954,0.31716060556185954,0.0,0.15030104343586473,0.4579933511281724,0.3076923076923077,0.35946627975403694,0.5653486326952135,0.20588235294117652
MAK,ENSG00000111837,5.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.5,3,115.3,47,4.5,0.1,0.1,5.2,8,115.3,39,0.03902862098872507,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.026752492122881274,0.026752492122881274,0.0,0.04289452835195829,0.350586836044266,0.3076923076923077,0.11082913361057341,0.3167114865517499,0.20588235294117652
BMP5,ENSG00000112175,68.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,68.9,3,13.6,47,0.0,0.0,68.9,13.6,8,12.5,39,5.0661764705882355,False,0,0,,,,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.048502484636882004,0.048502484636882004,0.0,0.24199021915946256,0.5496825268517702,0.3076923076923077,0.35297391897248404,0.5588562719136605,0.20588235294117652
TTK,ENSG00000112742,33.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,True,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,33.3,3,45.4,47,33.3,1.4,3.8,2.1,8,45.4,39,0.7334801762114537,False,4,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2588620054049082,0.2588620054049082,0.0,0.20090171287119396,0.5085940205635017,0.3076923076923077,0.19685318837795618,0.4027355413191327,0.20588235294117652
ENPP5,ENSG00000112796,237.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,34.4,3,237.9,47,34.4,9.3,1.6,237.9,8,49.5,39,0.144598570828079,False,1,0,Cancer-germline,10.1002/1878-0261.12900,Jamin2021_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,False,True,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.38221788407992396,0.38221788407992396,0.0,0.3241569384858359,0.6318492461781435,0.3076923076923077,0.520277771808495,0.7261601247496715,0.20588235294117652
PCDHB2,ENSG00000112852,5.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.4,3,4.4,47,5.4,1.7,0.7,2.6,8,4.4,39,1.2272727272727273,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT|Jamin2021_core,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,glioma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1114537872810392,0.1114537872810392,0.0,0.09434867226495929,0.402040979957267,0.3076923076923077,0.2640971274447485,0.469979480385925,0.20588235294117652
IL5,ENSG00000113525,4.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,False,False,False,False,False,Unsafe,Normal,Accepted published protein in non-permitted normal cells,Accepted published protein in non-permitted normal cells; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,True,False,False,False,legacy-06,https://pmc.ncbi.nlm.nih.gov/articles/PMC3445433/,legacy-06,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Normal,Accepted published protein in non-permitted normal cells,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.9,3,0.8,47,4.9,0.0,0.0,0.3,8,0.8,39,6.125,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1136/jitc-2023-007935,Carter2023_CT|Chang2019_TGCT|Wang2016_CT,True,False,31,20,COAD:validation|GBM:TCGA|LUSC:validation|PRAD:TCGA|READ:validation|STAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Accepted normal protein|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009672505712109673,0.009672505712109673,0.0,0.00500345767400236,0.31269576536631005,0.3076923076923077,0.03463618649040644,0.24051853943158297,0.20588235294117652
NUP155,ENSG00000113569,68.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,68.8,3,15.0,47,68.8,5.3,7.8,7.1,8,15.0,39,4.586666666666667,False,0,0,,,,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.38930782386422,0.38930782386422,0.0,0.3448932558298096,0.6525855635221174,0.3076923076923077,0.5260755031462618,0.7319578560874384,0.20588235294117652
ROPN1B,ENSG00000114547,208.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,True,True,False,False,True,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal RNA exceeds its applicable local category/IHC ceiling; Normal-cell RNA crosses a source-specific review trigger; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,208.3,3,36.8,47,208.3,0.2,0.2,36.8,8,14.1,39,5.660326086956522,False,6,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.10007857640761066,0.10007857640761066,0.0,0.0785945396088389,0.3862868473011466,0.3076923076923077,0.18601173015632974,0.3918940830975063,0.20588235294117652
CFAP92,ENSG00000114656,21.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,21.4,3,4.5,47,21.4,2.0,1.1,3.2,8,4.5,39,4.7555555555555555,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1371/journal.pgen.1011734,Chang2019_TGCT|Loriot2025_S2|Wang2016_CT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,glioma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.15698672740926264,0.15698672740926264,0.0,0.0827366629461816,0.3904289706384893,0.3076923076923077,0.21658061008704044,0.42246296302821695,0.20588235294117652
SLC30A3,ENSG00000115194,66.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,34.2,3,66.8,47,34.2,0.2,0.0,66.8,8,28.8,39,0.5119760479041917,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009862162686856923,0.009862162686856923,0.0,0.0145079542147638,0.3222002619070715,0.3076923076923077,0.15036044533354162,0.35624279827471816,0.20588235294117652
PCSK4,ENSG00000115257,64.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,64.1,3,6.9,47,64.1,1.0,0.2,3.1,8,6.9,39,9.289855072463768,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09477269209146072,0.09477269209146072,0.0,0.07803345781595582,0.38572576550826354,0.3076923076923077,0.3169515447967925,0.522833897737969,0.20588235294117652
PAPPA2,ENSG00000116183,54.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,54.9,3,6.4,47,0.4,0.0,54.9,6.4,8,6.1,39,8.578125,False,1,0,Cancer-germline|Cancer-placental|Cancer-reproductive,10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y,Bruggeman2018_GC|Gong2021_placenta_PC|Gong2021_reproductive_PC,True,False,31,20,BLCA:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|PAAD:TCGA|PAAD:validation|READ:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.022824762260592636,0.022824762260592636,0.0,0.03210935239623765,0.33980166008854534,0.3076923076923077,0.1715756159992059,0.3774579689403824,0.20588235294117652
SWT1,ENSG00000116668,37.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,37.2,3,8.9,47,37.2,5.8,5.4,4.5,8,8.9,39,4.179775280898877,False,0,0,,,,True,True,30,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2711314664803037,0.2711314664803037,0.0,0.26491147576996377,0.5726037834622715,0.3076923076923077,0.5087006797525637,0.7145830326937402,0.20588235294117652
SSX2IP,ENSG00000117155,102.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,102.6,3,115.1,47,102.6,1.9,6.1,22.1,8,115.1,39,0.891398783666377,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.37437742950913255,0.37437742950913255,0.0,0.3519768480530552,0.6596691557453629,0.3076923076923077,0.6254097293535605,0.8312920822947371,0.20588235294117652
KIF17,ENSG00000117245,22.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,22.6,3,4.5,47,22.6,0.1,0.0,1.7,8,4.5,39,5.022222222222222,False,0,0,,,,True,False,31,20,BRCA:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUSC:TCGA|OV:TCGA|OV:validation|PAAD:validation|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.007692307692307693,0.007692307692307693,0.0,0.0037424236260830655,0.3114347313183908,0.3076923076923077,0.0823750761949824,0.2882574291361589,0.20588235294117652
NSUN4,ENSG00000117481,86.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,86.6,3,7.8,47,86.6,4.4,5.3,5.2,8,7.8,39,11.102564102564102,False,0,0,,,,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|ovarian cancer|pancreatic cancer|prostate cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.32453434811263754,0.32453434811263754,0.0,0.3154970429731959,0.6231893506655036,0.3076923076923077,0.5287373106937096,0.7346196636348861,0.20588235294117652
NEK2,ENSG00000117650,65.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,65.2,3,18.7,47,65.2,0.9,3.1,2.4,8,18.7,39,3.486631016042781,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,cervical cancer|lymphoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.23783114516603113,0.23783114516603113,0.0,0.20721339142680917,0.5149056991191169,0.3076923076923077,0.21345981169605258,0.41934216463722906,0.20588235294117652
CHRNB4,ENSG00000117971,5.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.6,3,2.9,47,5.6,0.3,0.0,0.3,8,2.9,39,1.9310344827586206,False,2,0,Cancer-germline,10.1038/s41388-018-0357-2|10.1371/journal.pgen.1011734,Bruggeman2018_GC|Loriot2025_S2,True,False,31,0,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRP:TCGA|LUAD:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.062328187088789004,0.062328187088789004,0.0,0.03619171730519003,0.34388402499749776,0.3076923076923077,0.11065726097015208,0.31653961391132857,0.20588235294117652
ZNF541,ENSG00000118156,20.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,20.8,3,3.0,47,20.8,2.3,0.3,0.5,8,3.0,39,6.933333333333334,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|GBM:TCGA|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUSC:TCGA|OV:TCGA|OV:validation|READ:TCGA|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.046901942941546905,0.046901942941546905,0.0,0.019304688775946977,0.3269969964682547,0.3076923076923077,0.133007510628994,0.3388898635701705,0.20588235294117652
TNP1,ENSG00000118245,5787.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5787.7,3,4.9,47,5787.7,0.8,0.0,4.9,8,2.3,39,1181.1632653061224,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_testis_biased,True,False,31,20,LIHC:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0897942936773828,0.0897942936773828,0.0,0.04636300998166986,0.3540553176739776,0.3076923076923077,0.2053596419718161,0.4112419949129926,0.20588235294117652
DNAI7,ENSG00000118307,22.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,22.3,3,13.9,47,22.3,1.1,0.1,13.6,8,13.9,39,1.60431654676259,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.08922867267509124,0.08922867267509124,0.0,0.05754537707239138,0.3652376847646991,0.3076923076923077,0.22852714903117652,0.43440950197235306,0.20588235294117652
ADGB,ENSG00000118492,25.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,25.4,3,7.3,47,25.4,0.0,0.0,7.3,8,4.8,39,3.4794520547945202,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,29,20,COAD:TCGA|COAD:validation|GBM:validation|LUAD:TCGA|OV:validation|READ:TCGA|READ:validation|UCEC:TCGA,renal cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.004924037710922957,0.3126163454032307,0.3076923076923077,0.054747623364104485,0.260629976305281,0.20588235294117652
ZC2HC1C,ENSG00000119703,53.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,53.7,3,23.3,47,53.7,0.6,0.8,23.3,8,8.5,39,2.3047210300429186,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.17610154424124488,0.17610154424124488,0.0,0.1710864347921126,0.4787787424844203,0.3076923076923077,0.46832775216873346,0.67421010510991,0.20588235294117652
CFAP58,ENSG00000120051,13.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.0,3,8.2,47,13.0,0.4,0.4,8.2,8,3.2,39,1.5853658536585367,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,29,20,CESC:TCGA|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:validation|PAAD:validation|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,prostate cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.034407103298535587,0.034407103298535587,0.0,0.0368986962816821,0.3445910039739898,0.3076923076923077,0.2009466681358136,0.40682902107699015,0.20588235294117652
INSL6,ENSG00000120210,14.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,14.4,3,6.4,47,14.4,0.2,0.8,0.4,8,6.4,39,2.25,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,COAD:validation|KIRC:validation|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:validation|OV:TCGA|READ:validation|STAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04390340464889097,0.04390340464889097,0.0,0.024352276559086145,0.3320445842513938,0.3076923076923077,0.08359067528429646,0.289473028225473,0.20588235294117652
MAGEB4,ENSG00000120289,26.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.6,3,26.6,47,8.6,0.0,0.0,26.6,8,0.0,39,0.3233082706766917,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,False,True,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TEX11,ENSG00000120498,11.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11.3,3,57.0,47,11.3,0.0,0.2,0.1,8,57.0,39,0.19824561403508772,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|PAAD:TCGA|PAAD:validation|STAD:TCGA|TGCT:TCGA,endometrial cancer|melanoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.01849395948769189,0.01849395948769189,0.0,0.04192351605655515,0.34961582374886285,0.3076923076923077,0.07699072280328512,0.28287307574446163,0.20588235294117652
COIL,ENSG00000121058,95.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,95.7,3,19.7,47,95.7,11.1,12.5,11.8,8,19.7,39,4.8578680203045685,False,0,0,,,,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.5031056842749506,0.5031056842749506,0.0,0.4298170100277778,0.7375093177200855,0.3076923076923077,0.6423973545276804,0.848279707468857,0.20588235294117652
NCAPH,ENSG00000121152,34.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,34.3,3,36.4,47,34.3,1.9,5.1,1.9,8,36.4,39,0.9423076923076923,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|renal cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.3003635543369907,0.3003635543369907,0.0,0.25952459261900096,0.5672169003113087,0.3076923076923077,0.272761492324343,0.4786438452655195,0.20588235294117652
MND1,ENSG00000121211,15.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.4,3,26.0,47,15.4,2.0,2.3,2.4,8,26.0,39,0.5923076923076923,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|lymphoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.22543113452204364,0.22543113452204364,0.0,0.18834710586119247,0.4960394135535002,0.3076923076923077,0.25646594383510923,0.46234829677628575,0.20588235294117652
BCL2L14,ENSG00000121380,30.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,30.5,3,15.0,47,30.5,0.0,0.0,1.1,8,15.0,39,2.033333333333333,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,glioma|renal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.034512683578104136,0.034512683578104136,0.0,0.19084963772819089,0.49854194542049857,0.3076923076923077,0.12771740880260152,0.33359976174377803,0.20588235294117652
DPPA4,ENSG00000121570,4.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.1,3,12.1,47,4.1,0.0,2.1,0.1,8,12.1,39,0.33884297520661155,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,GBM:validation|PAAD:validation|TGCT:TCGA,colorectal cancer|lung cancer|renal cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1134238310708899,0.1134238310708899,0.0,0.007178193811232904,0.3148705015035406,0.3076923076923077,0.0770453017227457,0.2829276546639222,0.20588235294117652
KIF18A,ENSG00000121621,13.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.3,3,9.3,47,13.3,0.5,1.5,0.7,8,9.3,39,1.4301075268817205,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.15462712902019363,0.15462712902019363,0.0,0.1024958658512761,0.41018817354358383,0.3076923076923077,0.1463422537179849,0.35222460665916144,0.20588235294117652
GJA8,ENSG00000121634,5.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.7,3,0.1,47,5.7,0.0,0.0,0.0,8,0.1,39,57.0,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,OV:TCGA|OV:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
TMIGD3,ENSG00000121933,53.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,53.5,3,3.2,47,53.5,0.3,4.4,1.3,8,3.2,39,16.71875,False,0,0,,,,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.054868037022538736,0.054868037022538736,0.0,0.05697151664944513,0.3646638243417528,0.3076923076923077,0.2363342397796855,0.442216592720862,0.20588235294117652
PRM2,ENSG00000122304,11371.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11371.6,3,10.4,47,11371.6,1.4,0.0,10.4,8,4.5,39,1093.423076923077,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_testis_biased,True,False,31,20,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.150314190421591,0.150314190421591,0.0,0.08821824008169747,0.3959105477740052,0.3076923076923077,0.30081356460885095,0.5066959175500274,0.20588235294117652
HJURP,ENSG00000123485,10.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.8,3,46.8,47,10.8,1.4,2.9,2.0,8,46.8,39,0.2307692307692308,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|colorectal cancer|liver cancer|lung cancer|ovarian cancer|pancreatic cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2756356559250862,0.2756356559250862,0.0,0.2004735205941039,0.5081658282864117,0.3076923076923077,0.21165720804053853,0.4175395609817151,0.20588235294117652
IL13RA2,ENSG00000123496,29.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,29.1,3,11.7,47,29.1,0.1,0.4,4.3,8,11.7,39,2.4871794871794877,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.077066564634659,0.077066564634659,0.0,0.07042362890633873,0.37811593659864645,0.3076923076923077,0.27785644505530915,0.48373879799648567,0.20588235294117652
CKS2,ENSG00000123975,180.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,180.6,3,174.7,47,180.6,19.1,42.7,19.4,8,174.7,39,1.0337721808815112,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.692751661275709,0.692751661275709,0.0,0.5379526630417372,0.8456449707340449,0.3076923076923077,0.6901265739140925,0.896008926855269,0.20588235294117652
DAW1,ENSG00000123977,50.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,50.1,3,57.1,47,50.1,0.1,1.2,31.7,8,57.1,39,0.8774080560420315,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,29,20,BLCA:TCGA|CESC:TCGA|GBM:TCGA|GBM:validation|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|liver cancer|lung cancer|ovarian cancer|pancreatic cancer|prostate cancer|stomach cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04392148731771374,0.04392148731771374,0.0,0.03679895798747062,0.34449126567977834,0.3076923076923077,0.2097527580069008,0.4156351109480773,0.20588235294117652
FAM209A,ENSG00000124103,101.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,101.3,3,16.5,47,101.3,0.2,0.0,0.5,8,16.5,39,6.13939393939394,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,0,COAD:validation|GBM:validation|LUAD:TCGA|LUAD:validation|LUSC:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.07856171126194196,0.07856171126194196,0.0,0.044125105663567206,0.3518174133558749,0.3076923076923077,0.17116159730939864,0.37704395025057513,0.20588235294117652
WFDC3,ENSG00000124116,19.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,19.4,3,16.2,47,19.4,0.0,0.0,1.2,8,16.2,39,1.1975308641975309,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:validation|COAD:validation|GBM:validation|KIRC:validation|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:validation|OV:validation|PAAD:validation|READ:validation|STAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1294893648558512,0.1294893648558512,0.0,0.006223813204246837,0.3139161208965546,0.3076923076923077,0.044627155667342405,0.25050950860851895,0.20588235294117652
TP53TG5,ENSG00000124251,17.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,17.3,3,2.9,47,17.3,0.1,0.1,0.4,8,2.9,39,5.9655172413793105,False,0,0,,,,True,False,31,20,COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRP:TCGA|LIHC:validation|READ:validation|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013744903902154923,0.013744903902154923,0.0,0.01717589875310658,0.3248682064454143,0.3076923076923077,0.11245575662206579,0.3183381095632423,0.20588235294117652
CRISP2,ENSG00000124490,490.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,490.9,3,17.1,47,490.9,0.1,0.0,17.1,8,16.5,39,28.707602339181282,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02494938569487201,0.02494938569487201,0.0,0.08465033120623616,0.39234263889854387,0.3076923076923077,0.1605756387485124,0.36645799168968896,0.20588235294117652
OPN5,ENSG00000124818,2.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.5,3,0.4,47,2.5,0.0,0.0,0.0,8,0.4,39,6.25,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,31,20,,lung cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.012605042016806723,0.21848739495798325,0.20588235294117652
PIWIL1,ENSG00000125207,41.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,41.5,3,1.1,47,41.5,0.0,0.0,0.3,8,1.1,39,37.72727272727273,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Jamin2021_core|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,COAD:TCGA|COAD:validation|OV:validation|PAAD:validation|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009672505712109673,0.009672505712109673,0.0,0.0,0.3076923076923077,0.3076923076923077,0.03335961157098027,0.2392419645121568,0.20588235294117652
HROB,ENSG00000125319,11.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11.1,3,9.2,47,11.1,0.8,0.9,1.4,8,9.2,39,1.2065217391304348,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.11694062048611084,0.11694062048611084,0.0,0.09040130208585605,0.39809360977816377,0.3076923076923077,0.19479708381397243,0.40067943675514894,0.20588235294117652
GRK4,ENSG00000125388,41.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,41.1,3,12.1,47,41.1,3.3,1.5,3.0,8,12.1,39,3.396694214876033,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer|liver cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.17899796396203227,0.17899796396203227,0.0,0.2009015012550372,0.508593808947345,0.3076923076923077,0.4823016581774828,0.6881840111186592,0.20588235294117652
TEKT3,ENSG00000125409,30.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,30.2,3,4.7,47,30.2,0.9,0.2,4.7,8,2.5,39,6.425531914893616,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BRCA:TCGA|BRCA:validation|COAD:validation|GBM:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|READ:validation|TGCT:TCGA|UCEC:TCGA,colorectal cancer|renal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03613187623221341,0.03613187623221341,0.0,0.020918322379189645,0.3286106300714974,0.3076923076923077,0.1332159083741442,0.3390982613153207,0.20588235294117652
FNDC11,ENSG00000125531,105.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,105.0,3,2.3,47,105.0,0.3,0.1,2.3,8,1.2,39,45.652173913043484,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04891548580868969,0.04891548580868969,0.0,0.02853206291504873,0.33622437060735644,0.3076923076923077,0.110918568893258,0.31680092183443453,0.20588235294117652
BANF2,ENSG00000125888,107.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,107.2,3,19.8,47,107.2,0.0,0.0,0.3,8,19.8,39,5.414141414141414,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,LIHC:TCGA|LIHC:validation|LUAD:validation|OV:TCGA|PAAD:TCGA|READ:validation|STAD:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.024989047577324106,0.024989047577324106,0.0,0.00500345767400236,0.31269576536631005,0.3076923076923077,0.06611218661595254,0.27199453955712904,0.20588235294117652
SIRPD,ENSG00000125900,56.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,56.2,3,2.7,47,56.2,0.1,0.2,0.2,8,2.7,39,20.814814814814813,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|COAD:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|LUAD:TCGA|LUAD:validation|LUSC:validation|READ:validation|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.030008525149190113,0.030008525149190113,0.0,0.026536502094370727,0.33422880978667846,0.3076923076923077,0.09962974891282014,0.3055121018539967,0.20588235294117652
DLGAP5,ENSG00000126787,16.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.9,3,40.9,47,16.9,2.6,3.9,1.4,8,40.9,39,0.41320293398533003,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2718124772069792,0.2718124772069792,0.0,0.22219485845030593,0.5298871661426137,0.3076923076923077,0.18613410325647728,0.3920164561976538,0.20588235294117652
PLAAT1,ENSG00000127252,71.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,71.6,3,86.9,47,71.6,0.6,0.1,5.7,8,86.9,39,0.8239355581127732,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.18423918664998704,0.18423918664998704,0.0,0.16599251958690275,0.47368482727921046,0.3076923076923077,0.3429866623374595,0.548869015278636,0.20588235294117652
AUNIP,ENSG00000127423,15.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.5,3,6.1,47,15.5,0.5,1.7,0.5,8,6.1,39,2.540983606557377,False,5,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,melanoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.053459908485766316,0.053459908485766316,0.0,0.05770320759852738,0.3653955152908351,0.3076923076923077,0.1844479694090082,0.3903303223501847,0.20588235294117652
PKMYT1,ENSG00000127564,55.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,55.3,3,27.3,47,55.3,0.3,3.0,3.2,8,27.3,39,2.0256410256410255,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2559864166081783,0.2559864166081783,0.0,0.1907696477956308,0.4984619554879385,0.3076923076923077,0.3756349724022231,0.5815173253433996,0.20588235294117652
SPINK2,ENSG00000128040,5123.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,333.6,3,5123.9,47,333.6,0.4,0.0,5123.9,8,13.1,39,0.0651066570385839,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.11119554259776601,0.11119554259776601,0.0,0.14671643334948692,0.45440874104179463,0.3076923076923077,0.24740461436571667,0.4532869673068932,0.20588235294117652
RFPL3,ENSG00000128276,24.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,24.2,3,2.3,47,24.2,0.2,0.1,0.3,8,2.3,39,10.521739130434783,False,0,0,,,,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|GBM:TCGA|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PRAD:TCGA|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.040414450225357106,0.040414450225357106,0.0,0.016693268900078485,0.3243855765923862,0.3076923076923077,0.09257474929915023,0.29845710224032673,0.20588235294117652
IGLL1,ENSG00000128322,24.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,24.5,3,69.3,47,24.5,0.1,0.0,0.2,8,69.3,39,0.35353535353535354,False,3,0,Cancer-germline|Cancer-reproductive,10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Gong2021_reproductive_PC|Loriot2025_S2|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,BRCA:validation|CESC:TCGA|KIRP:TCGA|LUAD:TCGA|LUSC:TCGA|OV:validation|PAAD:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.10916999314929562,0.10916999314929562,0.0,0.021197789657808032,0.32889009735011576,0.3076923076923077,0.07827739664015548,0.284159749581332,0.20588235294117652
C22orf23,ENSG00000128346,92.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,92.8,3,25.2,47,92.8,1.3,5.2,12.0,8,25.2,39,3.6825396825396823,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.3158078494686498,0.3158078494686498,0.0,0.2541328622614083,0.561825169953716,0.3076923076923077,0.4507899254173549,0.6566722783585315,0.20588235294117652
RIBC2,ENSG00000128408,29.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,29.8,3,13.0,47,29.8,0.2,0.3,9.4,8,13.0,39,2.292307692307692,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|endometrial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03754157853531094,0.03754157853531094,0.0,0.04267934485208618,0.3503716525443939,0.3076923076923077,0.12124094409226678,0.3271232970334433,0.20588235294117652
CCDC136,ENSG00000128596,180.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,180.5,3,85.4,47,180.5,2.7,1.3,13.1,8,85.4,39,2.113583138173302,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.15911323433923452,0.15911323433923452,0.0,0.2721282742368288,0.5798205819291364,0.3076923076923077,0.4681640552044339,0.6740464081456103,0.20588235294117652
FEZF1,ENSG00000128610,4.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.4,3,13.4,47,4.4,0.0,0.0,0.0,8,13.4,39,0.3283582089552239,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.07764924151478772,0.2835315944559642,0.20588235294117652
QRICH2,ENSG00000129646,17.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,17.7,3,7.3,47,17.7,1.2,1.0,2.0,8,7.3,39,2.4246575342465753,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1280211699465062,0.1280211699465062,0.0,0.11113351466854118,0.41882582236084887,0.3076923076923077,0.3466439201317084,0.5525262730728849,0.20588235294117652
AANAT,ENSG00000129673,4.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.5,3,10.6,47,4.5,0.1,0.0,0.2,8,10.6,39,0.42452830188679247,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04919511673752171,0.04919511673752171,0.0,0.02653246629978518,0.3342247739920929,0.3076923076923077,0.12040048021505821,0.32628283315623474,0.20588235294117652
SGO1,ENSG00000129810,6.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.5,3,12.6,47,6.5,0.7,1.7,0.6,8,12.6,39,0.5158730158730159,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,cervical cancer|colorectal cancer|melanoma|ovarian cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1640799055020006,0.1640799055020006,0.0,0.1322588788014695,0.4399511864937772,0.3076923076923077,0.14306043070663257,0.34894278364780906,0.20588235294117652
TSPAN16,ENSG00000130167,130.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,130.9,3,5.1,47,130.9,0.0,0.0,0.2,8,5.1,39,25.666666666666668,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,COAD:validation|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005901766647252961,0.005901766647252961,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.04742628953482308,0.2533086424759996,0.20588235294117652
ATP8B3,ENSG00000130270,21.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,21.3,3,5.8,47,21.3,0.5,0.3,1.2,8,5.8,39,3.6724137931034484,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:validation|PAAD:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.11308729418843866,0.11308729418843866,0.0,0.03368333410382551,0.3413756417961332,0.3076923076923077,0.1606881100806932,0.3665704630218697,0.20588235294117652
IQCN,ENSG00000130518,27.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,27.4,3,3.4,47,27.4,3.3,0.3,3.1,8,3.4,39,8.058823529411764,False,1,0,Cancer-germline,10.1002/1878-0261.12900,Jamin2021_CT,True,False,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1446503571955517,0.1446503571955517,0.0,0.07601468809638545,0.38370699578869316,0.3076923076923077,0.26291722965687475,0.46879958259805127,0.20588235294117652
SAG,ENSG00000130561,3.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.0,3,1421.5,47,3.0,0.0,0.0,0.9,8,1421.5,39,0.002110446711220542,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BRCA:validation|PAAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.03519382352242101,0.24107617646359752,0.20588235294117652
HBZ,ENSG00000130656,7.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.1,3,3.9,47,7.1,0.1,0.6,0.5,8,3.9,39,1.8205128205128205,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BRCA:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.026818503147537406,0.026818503147537406,0.0,0.007525525769840948,0.31521783346214866,0.3076923076923077,0.08971793499189572,0.29560028793307225,0.20588235294117652
HSD17B3,ENSG00000130948,35.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,35.7,3,14.8,47,35.7,1.4,0.1,3.4,8,14.8,39,2.4121621621621623,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUSC:TCGA|LUSC:validation|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,endometrial cancer|liver cancer|lung cancer|ovarian cancer|pancreatic cancer|renal cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.15909088719273762,0.15909088719273762,0.0,0.07450724656816517,0.38219955426047286,0.3076923076923077,0.362814506752851,0.5686968596940275,0.20588235294117652
NUTM2F,ENSG00000130950,1.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.8,3,0.1,47,1.8,0.0,0.0,0.0,8,0.1,39,18.0,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,29,0,COAD:validation|READ:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0031512605042016803,0.20903361344537819,0.20588235294117652
TTLL9,ENSG00000131044,6.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.9,3,15.0,47,4.9,0.1,0.0,6.0,8,15.0,39,0.3266666666666667,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BRCA:TCGA|BRCA:validation|GBM:TCGA|GBM:validation|KIRP:TCGA|OV:TCGA|OV:validation|UCEC:TCGA,cervical cancer|endometrial cancer|glioma|head and neck cancer|melanoma|ovarian cancer|pancreatic cancer|skin cancer|stomach cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.017222521364234092,0.017222521364234092,0.0,0.008254041040926289,0.315946348733234,0.3076923076923077,0.13242255118903945,0.33830490413021597,0.20588235294117652
TEX101,ENSG00000131126,114.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,114.4,3,1.5,47,114.4,0.3,0.2,0.9,8,1.5,39,76.26666666666667,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,CESC:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|LIHC:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|STAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.05020936876296325,0.05020936876296325,0.0,0.04312869058831716,0.35082099828062485,0.3076923076923077,0.10063996106195594,0.30652231400313246,0.20588235294117652
KRT33B,ENSG00000131738,0.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.1,3,80.2,47,0.1,0.0,0.0,0.2,8,80.2,39,0.0012468827930174563,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.21392001270483757,0.21392001270483757,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.001893939393939394,0.2077762923351159,0.20588235294117652
TOP2A,ENSG00000131747,63.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,63.8,3,124.5,47,63.8,4.1,15.4,9.3,8,124.5,39,0.5124497991967871,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.46798722843499485,0.46798722843499485,0.0,0.3666882028062145,0.6743805104985222,0.3076923076923077,0.3627162104715602,0.5685985634127367,0.20588235294117652
ZSCAN5A,ENSG00000131848,24.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,24.4,3,5.6,47,24.4,3.4,1.8,5.5,8,5.6,39,4.357142857142857,False,1,0,Cancer-germline,10.1038/s41388-018-0357-2,Bruggeman2018_GC,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.25048480068674767,0.25048480068674767,0.0,0.2250581134461296,0.5327504211384373,0.3076923076923077,0.4676276102307583,0.6735099631719348,0.20588235294117652
LIN28A,ENSG00000131914,5.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.0,3,0.3,47,5.0,0.0,0.0,0.1,8,0.3,39,16.666666666666668,False,5,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734,Bruggeman2018_GC|Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|KICH:TCGA|KIRP:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,cervical cancer|skin cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.020133745197683815,0.22601609813886034,0.20588235294117652
BRME1,ENSG00000132016,14.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,14.3,3,5.3,47,14.3,1.7,0.2,3.7,8,5.3,39,2.69811320754717,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,cervical cancer|colorectal cancer|lung cancer|melanoma|ovarian cancer|skin cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.12536930721663955,0.12536930721663955,0.0,0.12335962260875796,0.4310519303010657,0.3076923076923077,0.31796261670159764,0.5238449696427742,0.20588235294117652
CCT6B,ENSG00000132141,122.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,122.5,3,5.4,47,122.5,2.3,0.6,5.4,8,4.9,39,22.685185185185183,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.18219359808284835,0.18219359808284835,0.0,0.17335591609648798,0.4810482237887957,0.3076923076923077,0.44388961812601957,0.6497719710671961,0.20588235294117652
RGS22,ENSG00000132554,59.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,59.6,3,10.3,47,59.6,5.4,0.5,10.3,8,6.4,39,5.786407766990291,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:TCGA|BRCA:validation|COAD:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.05849236263407537,0.05849236263407537,0.0,0.019696150843691827,0.3273884585359995,0.3076923076923077,0.1571835286382069,0.3630658815793834,0.20588235294117652
ATP1A4,ENSG00000132681,15.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.8,3,4.9,47,15.8,0.0,6.1,1.5,8,4.9,39,3.2244897959183674,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|GBM:validation|LUAD:validation|PAAD:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.029795694501576857,0.029795694501576857,0.0,0.07492645069102064,0.3826187583833284,0.3076923076923077,0.07648197618968536,0.28236432913086185,0.20588235294117652
TESMIN,ENSG00000132749,51.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,51.0,3,7.4,47,51.0,0.8,0.3,4.2,8,7.4,39,6.891891891891891,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09330800014610302,0.09330800014610302,0.0,0.12822683894923326,0.43591914664154097,0.3076923076923077,0.231919556425161,0.4378019093663375,0.20588235294117652
RNF17,ENSG00000132972,23.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,23.6,3,0.3,47,23.6,0.4,1.5,0.3,8,0.3,39,78.66666666666667,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|LIHC:TCGA|LIHC:validation|TGCT:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline|Cancer-placental,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.01502557544757033,0.22090792838874684,0.20588235294117652
CCNA1,ENSG00000133101,79.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,79.0,3,21.5,47,79.0,0.4,0.0,17.5,8,21.5,39,3.6744186046511627,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|SKCM:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04205442234385265,0.04205442234385265,0.0,0.09817661846350371,0.40586892615581144,0.3076923076923077,0.2952769479175125,0.501159300858689,0.20588235294117652
FAM83F,ENSG00000133477,39.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,39.7,3,19.7,47,39.7,0.3,0.1,8.7,8,19.7,39,2.0152284263959395,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer|ovarian cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2363241137871847,0.2363241137871847,0.0,0.26595242623264326,0.573644733924951,0.3076923076923077,0.26076429168811,0.4666466446292865,0.20588235294117652
LRRIQ1,ENSG00000133640,15.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.0,3,13.6,47,15.0,0.2,0.0,13.3,8,13.6,39,1.1029411764705883,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04333896804314578,0.04333896804314578,0.0,0.03487597279932647,0.3425682804916342,0.3076923076923077,0.1853911543561059,0.3912735072972824,0.20588235294117652
ADAM20,ENSG00000134007,5.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.1,3,0.4,47,5.1,0.1,0.0,0.2,8,0.4,39,12.749999999999998,False,4,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|COAD:validation|GBM:validation|PAAD:validation|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.007920792079207921,0.007920792079207921,0.0,0.0037831021437578823,0.3114754098360656,0.3076923076923077,0.02153361344537815,0.22741596638655467,0.20588235294117652
TRPM1,ENSG00000134160,2.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.1,3,17.0,47,2.1,0.0,0.0,0.1,8,17.0,39,0.12352941176470589,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,False,31,20,SKCM:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06394557823129253,0.06394557823129253,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.050826208485381996,0.2567085614265585,0.20588235294117652
CDCA8,ENSG00000134690,21.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,21.9,3,37.8,47,21.9,1.8,4.2,2.8,8,37.8,39,0.5793650793650794,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.329069643456107,0.329069643456107,0.0,0.28246103623089286,0.5901533439232005,0.3076923076923077,0.3154111787938896,0.5212935317350661,0.20588235294117652
ACRV1,ENSG00000134940,113.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,113.4,3,3.4,47,113.4,0.0,0.1,3.4,8,2.4,39,33.352941176470594,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.007329760403530896,0.3150220680958386,0.3076923076923077,0.05014341595223948,0.256025768893416,0.20588235294117652
CSN2,ENSG00000135222,560.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.1,3,560.3,47,0.1,0.0,0.0,560.3,8,5.4,39,0.00017847581652686063,False,1,0,Cancer-germline,10.1038/ncomms10499,Wang2016_CT,True,True,31,20,BRCA:validation|LIHC:validation,colorectal cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,False,True,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.07012987012987014,0.07012987012987014,0.0,0.02620456466610313,0.3338968723584108,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
TROAP,ENSG00000135451,28.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,28.3,3,50.5,47,28.3,2.5,5.0,5.2,8,50.5,39,0.5603960396039604,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,cervical cancer|colorectal cancer|endometrial cancer|liver cancer|lung cancer|ovarian cancer|pancreatic cancer|prostate cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.36004149194194446,0.36004149194194446,0.0,0.2757492423153538,0.5834415500076615,0.3076923076923077,0.3076737769118971,0.5135561298530736,0.20588235294117652
EGR4,ENSG00000135625,3.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.8,3,18.6,47,3.8,0.1,0.0,0.0,8,18.6,39,0.2043010752688172,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|LUAD:TCGA|LUSC:TCGA|PAAD:TCGA|PAAD:validation|PRAD:TCGA|SKCM:TCGA|STAD:TCGA,melanoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.09775026026710257,0.30363261320827906,0.20588235294117652
GPR55,ENSG00000135898,4.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.5,3,4.3,47,4.5,0.0,0.0,0.5,8,4.3,39,1.0465116279069768,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|READ:TCGA|READ:validation|SKCM:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.10072833398401249,0.10072833398401249,0.0,0.07656775587484037,0.3842600635671481,0.3076923076923077,0.08031851107142729,0.2862008640126038,0.20588235294117652
SERPINE2,ENSG00000135919,1054.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1054.7,3,159.8,47,55.9,284.1,1054.7,27.1,8,159.8,39,6.600125156445557,False,0,0,,,,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.6682479324117,0.6682479324117,0.0,0.49648364690419067,0.8041759545964984,0.3076923076923077,0.6990815589318163,0.9049639118729929,0.20588235294117652
TSGA10,ENSG00000135951,50.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,50.1,3,12.2,47,50.1,0.4,0.4,12.2,8,3.1,39,4.106557377049181,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1325410737175443,0.1325410737175443,0.0,0.09010614364227798,0.3977984513345857,0.3076923076923077,0.25962104152966514,0.46550339447084166,0.20588235294117652
USP44,ENSG00000136014,23.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,23.5,3,3.9,47,23.5,0.9,0.1,1.6,8,3.9,39,6.0256410256410255,False,1,0,Cancer-germline,10.1002/1878-0261.12900,Jamin2021_CT|Jamin2021_core,True,False,31,0,BLCA:TCGA|BRCA:validation|CESC:TCGA|GBM:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:validation|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.11936605928887811,0.11936605928887811,0.0,0.07513388015683165,0.38282618784913935,0.3076923076923077,0.2200020342003425,0.425884387141519,0.20588235294117652
IGF2BP3,ENSG00000136231,27.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,True,False,True,False,False,True,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,27.9,3,7.1,47,5.0,0.5,27.9,0.8,8,7.1,39,3.9295774647887325,False,4,1,Cancer-germline|Cancer-placental,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-020-19141-w,Bradley2020_CPA|Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,cervical cancer|colorectal cancer|endometrial cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04870721207480253,0.04870721207480253,0.0,0.06286585373688955,0.3705581614291973,0.3076923076923077,0.05793264469735058,0.2638149976385271,0.20588235294117652
NKX2-8,ENSG00000136327,7.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.7,3,7.6,47,7.7,0.0,0.0,0.1,8,7.6,39,1.0131578947368423,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,29,20,BLCA:TCGA|CESC:TCGA|HNSC:TCGA|KIRP:TCGA|LUAD:TCGA|LUSC:TCGA|OV:TCGA|PAAD:TCGA|PAAD:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.026541601528573912,0.026541601528573912,0.0,0.02636685801522334,0.334059165707531,0.3076923076923077,0.083497298912815,0.2893796518539915,0.20588235294117652
MYCBPAP,ENSG00000136449,63.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,63.2,3,5.0,47,63.2,2.4,0.3,4.6,8,5.0,39,12.64,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06519460672167426,0.06519460672167426,0.0,0.04919270875865881,0.35688501645096654,0.3076923076923077,0.1969431523379273,0.4028255052791038,0.20588235294117652
CSH1,ENSG00000136488,9508.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9508.4,3,38.3,47,0.1,0.3,9508.4,6.4,8,38.3,39,248.26109660574414,False,0,0,Cancer-germline|Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_placenta_PC|Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.16223920830102287,0.16223920830102287,0.0,0.07565844210302115,0.38335074979532885,0.3076923076923077,0.1701839568096193,0.3760663097507958,0.20588235294117652
BRIP1,ENSG00000136492,4.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.7,3,3.6,47,4.7,0.6,0.2,0.5,8,3.6,39,1.3055555555555556,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0796193629596816,0.0796193629596816,0.0,0.05285789407959161,0.36055020177189934,0.3076923076923077,0.0957478086498057,0.3016301615909822,0.20588235294117652
ODF2,ENSG00000136811,308.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,308.7,3,36.6,47,308.7,13.8,11.3,19.9,8,36.6,39,8.434426229508196,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer|liver cancer|ovarian cancer|prostate cancer|renal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.6053548606111112,0.6053548606111112,0.0,0.44781460343343693,0.7555069111257446,0.3076923076923077,0.6854845497769992,0.8913669027181758,0.20588235294117652
HEMGN,ENSG00000136929,49.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,49.1,3,243.6,47,49.1,0.0,5.8,0.3,8,243.6,39,0.201559934318555,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,20,COAD:validation|GBM:validation|KICH:TCGA|READ:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.16826269066062421,0.16826269066062421,0.0,0.02042875157629256,0.32812105926860025,0.3076923076923077,0.11275462027868684,0.31863697321986334,0.20588235294117652
GCM1,ENSG00000137270,19.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,19.5,3,3.4,47,0.6,0.0,19.5,0.1,8,3.4,39,5.735294117647059,False,0,0,Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_placenta_PC|Gong2021_reproductive_PC,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,lymphoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013632901751713633,0.013632901751713633,0.0,0.008745881300085426,0.3164381889923931,0.3076923076923077,0.08852561665860897,0.2944079695997855,0.20588235294117652
C6orf52,ENSG00000137434,13.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.3,3,4.3,47,13.3,1.8,0.2,3.4,8,4.3,39,3.0930232558139537,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.08031235088057245,0.08031235088057245,0.0,0.056551280528170274,0.364243588220478,0.3076923076923077,0.2992216180191171,0.5051039709602936,0.20588235294117652
TTC29,ENSG00000137473,69.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,69.8,3,19.4,47,69.8,0.0,0.0,19.4,8,5.9,39,3.597938144329897,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PRAD:TCGA|READ:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.006993006993006994,0.3146853146853147,0.3076923076923077,0.06476841153117235,0.27065076447234887,0.20588235294117652
CFAP300,ENSG00000137691,29.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,29.3,3,28.2,47,29.3,4.0,3.2,28.2,8,23.6,39,1.0390070921985817,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.12785121728704768,0.12785121728704768,0.0,0.12286068675716373,0.4305529944494714,0.3076923076923077,0.3001269751743816,0.5060093281155581,0.20588235294117652
BTG4,ENSG00000137707,22.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,22.0,3,4.3,47,22.0,0.0,0.0,1.4,8,4.3,39,5.116279069767442,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,GBM:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.022175536881419235,0.22805788982259576,0.20588235294117652
KNL1,ENSG00000137812,16.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.4,3,7.2,47,16.4,0.3,1.3,0.3,8,7.2,39,2.2777777777777777,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,cervical cancer|colorectal cancer|head and neck cancer|lymphoma|pancreatic cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.11787260844496958,0.11787260844496958,0.0,0.08604467402302453,0.3937369817153322,0.3076923076923077,0.12549155215890923,0.33137390510008574,0.20588235294117652
CYP19A1,ENSG00000137869,120.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,120.5,3,8.2,47,6.1,3.1,120.5,2.3,8,8.2,39,14.695121951219514,False,0,0,Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_placenta_PC|Gong2021_reproductive_PC,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.17155241903577542,0.17155241903577542,0.0,0.04997429960879116,0.3576666073010989,0.3076923076923077,0.18098900346221475,0.38687135640339126,0.20588235294117652
MNS1,ENSG00000138587,46.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,46.8,3,22.0,47,46.8,4.1,1.6,20.6,8,22.0,39,2.127272727272727,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.19195859777243537,0.19195859777243537,0.0,0.14498949634409897,0.4526818040364067,0.3076923076923077,0.4484602752441344,0.6543426281853109,0.20588235294117652
APH1B,ENSG00000138613,119.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,119.4,3,18.9,47,119.4,11.2,7.8,15.7,8,18.9,39,6.317460317460318,False,0,0,,,,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.5097671124355193,0.5097671124355193,0.0,0.34628493237885355,0.6539772400711612,0.3076923076923077,0.6101165050983621,0.8159988580395386,0.20588235294117652
HERC5,ENSG00000138646,56.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,56.2,3,18.6,47,56.2,16.7,9.9,14.9,8,18.6,39,3.021505376344086,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.39998121238102774,0.39998121238102774,0.0,0.307041640572912,0.6147339482652197,0.3076923076923077,0.5650852874589576,0.7709676404001341,0.20588235294117652
IL21,ENSG00000138684,0.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.7,3,5.8,47,0.7,0.0,0.0,0.0,8,5.8,39,0.12068965517241378,False,2,0,Cancer-germline|Cancer-reproductive,10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:validation|LUAD:validation|LUSC:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.041552071605222576,0.34924437929753027,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
FBN2,ENSG00000138829,65.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,True,False,False,True,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,65.0,3,4.4,47,4.1,1.5,65.0,1.8,8,4.4,39,14.772727272727272,False,0,0,,,,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.021399515077809236,0.021399515077809236,0.0,0.04279079949406519,0.3504831071863729,0.3076923076923077,0.17799778833437935,0.38388014127555586,0.20588235294117652
CCDC65,ENSG00000139537,36.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,36.2,3,25.8,47,36.2,0.6,0.1,25.8,8,18.9,39,1.4031007751937985,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09599509964835043,0.09599509964835043,0.0,0.042864552243935136,0.35055685993624286,0.3076923076923077,0.2513545801255181,0.4572369330666946,0.20588235294117652
DHH,ENSG00000139549,16.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.2,3,1.0,47,16.2,0.3,0.6,0.7,8,1.0,39,16.2,False,1,0,Cancer-germline,10.1002/1878-0261.12900,Jamin2021_CT,True,False,31,0,BLCA:TCGA|BRCA:validation|GBM:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.030386868879159,0.030386868879159,0.0,0.027713748000633247,0.33540605569294096,0.3076923076923077,0.10886123680241326,0.3147435897435898,0.20588235294117652
MORN3,ENSG00000139714,4.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.4,3,6.0,47,4.4,0.4,0.8,3.8,8,6.0,39,0.7333333333333334,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.07534867153812591,0.07534867153812591,0.0,0.05274395806005743,0.36043626575236515,0.3076923076923077,0.15512805597422094,0.3610104089153975,0.20588235294117652
DIAPH3,ENSG00000139734,18.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,18.3,3,7.0,47,18.3,0.6,3.4,0.8,8,7.0,39,2.6142857142857143,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Jamin2021_core|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.10990593241612462,0.10990593241612462,0.0,0.10779711801681142,0.4154894257091191,0.3076923076923077,0.17623574682398213,0.38211809976515865,0.20588235294117652
ZIC5,ENSG00000139800,3.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.6,3,27.0,47,3.6,0.0,0.0,0.0,8,27.0,39,0.13333333333333333,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:validation|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0731955569814615,0.27907790992263803,0.20588235294117652
TSSK4,ENSG00000139908,37.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,37.0,3,4.0,47,37.0,1.1,0.4,1.3,8,4.0,39,9.25,False,0,0,,,,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA,endometrial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.12727785117934803,0.12727785117934803,0.0,0.08904140839044304,0.39673371608275076,0.3076923076923077,0.26603231807106087,0.4719146710122374,0.20588235294117652
AK7,ENSG00000140057,23.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.4,3,23.5,47,7.4,0.4,0.4,23.5,8,17.7,39,0.3148936170212766,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|liver cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.18122264028806087,0.18122264028806087,0.0,0.13570504407448528,0.44339735176679296,0.3076923076923077,0.3711867879584079,0.5770691408995845,0.20588235294117652
FAM181A,ENSG00000140067,31.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,31.6,3,13.5,47,31.6,0.0,0.0,1.9,8,13.5,39,2.340740740740741,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|OV:TCGA|OV:validation|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.019819819819819826,0.019819819819819826,0.0,0.0,0.3076923076923077,0.3076923076923077,0.16674760150018786,0.3726299544413644,0.20588235294117652
WDR93,ENSG00000140527,11.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11.2,3,8.6,47,11.2,0.3,0.1,8.6,8,6.8,39,1.3023255813953487,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer|endometrial cancer|head and neck cancer|liver cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0446341014191917,0.0446341014191917,0.0,0.015844655148238927,0.3235369628405466,0.3076923076923077,0.1483609054490498,0.3542432583902263,0.20588235294117652
SEPTIN12,ENSG00000140623,96.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,96.1,3,3.1,47,96.1,0.0,0.0,0.1,8,3.1,39,30.999999999999996,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,0,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.044138442532454865,0.2500207954736314,0.20588235294117652
CMTM2,ENSG00000140932,630.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,630.9,3,1.4,47,630.9,0.2,0.2,0.7,8,1.4,39,450.64285714285717,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:validation|COAD:validation|GBM:TCGA|GBM:validation|LIHC:validation|PAAD:TCGA|PAAD:validation|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.05991666827580141,0.05991666827580141,0.0,0.009966236830329904,0.3176585445226376,0.3076923076923077,0.10822293867750207,0.3141052916186786,0.20588235294117652
ADAD2,ENSG00000140955,62.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,62.9,3,3.6,47,62.9,0.2,0.0,0.5,8,3.6,39,17.47222222222222,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|GBM:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.07752929616373246,0.07752929616373246,0.0,0.016741942162433573,0.3244342498547413,0.3076923076923077,0.0582614684024345,0.26414382134361103,0.20588235294117652
TIGD7,ENSG00000140993,9.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.8,3,9.5,47,8.9,9.8,3.2,5.5,8,9.5,39,1.0315789473684212,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2829896958783514,0.2829896958783514,0.0,0.25452596087440543,0.5622182685667132,0.3076923076923077,0.5104531268876186,0.7163354798287951,0.20588235294117652
KIF2B,ENSG00000141200,73.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,73.2,3,0.0,47,73.2,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,False,True,31,20,,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
MTNAP1,ENSG00000141219,38.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,38.5,3,22.9,47,38.5,15.1,11.8,13.9,8,22.9,39,1.6812227074235808,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT|Jamin2021_core,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.5296396690458107,0.5296396690458107,0.0,0.45259368513402365,0.7602859928263314,0.3076923076923077,0.6556738815288864,0.8615562344700629,0.20588235294117652
SPATA22,ENSG00000141255,223.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,223.4,3,2.7,47,223.4,0.2,3.4,1.0,8,2.7,39,82.74074074074073,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,0,GBM:TCGA|GBM:validation|LUSC:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03932590817350326,0.03932590817350326,0.0,0.04474850690135433,0.35244081459366206,0.3076923076923077,0.11375088624490488,0.3196332391860814,0.20588235294117652
SPACA3,ENSG00000141316,121.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,121.8,3,20.3,47,121.8,0.1,0.1,0.2,8,20.3,39,6.0,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,COAD:TCGA|COAD:validation|LUAD:TCGA|LUAD:validation|PAAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.011727009365699564,0.011727009365699564,0.0,0.011267949395924013,0.3189602570882317,0.3076923076923077,0.08100229497197023,0.2868846479131467,0.20588235294117652
ZMYND15,ENSG00000141497,27.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,27.5,3,5.3,47,27.5,0.7,1.1,1.6,8,5.3,39,5.188679245283019,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1543463573656182,0.1543463573656182,0.0,0.14102981117994612,0.44872211887225383,0.3076923076923077,0.3269208280990625,0.5328031810402389,0.20588235294117652
FBXO15,ENSG00000141665,6.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.9,3,3.9,47,6.9,0.3,0.0,3.9,8,3.3,39,1.7692307692307694,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:TCGA|BRCA:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|SKCM:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.026969332710131678,0.026969332710131678,0.0,0.018181536425851606,0.32587384411815934,0.3076923076923077,0.15643477975902167,0.36231713270019816,0.20588235294117652
ZNF473,ENSG00000142528,41.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,41.1,3,7.1,47,41.1,4.5,2.9,7.1,8,6.5,39,5.788732394366198,False,0,0,,,,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|colorectal cancer|glioma|lung cancer|melanoma|prostate cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.30292419998302356,0.30292419998302356,0.0,0.24476622091635342,0.5524585286086612,0.3076923076923077,0.4983928128407433,0.7042751657819198,0.20588235294117652
GARIN5A,ENSG00000142530,74.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,74.5,3,9.0,47,74.5,2.5,0.4,1.9,8,9.0,39,8.277777777777779,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.08486163877010552,0.08486163877010552,0.0,0.10145523465822462,0.4091475423505323,0.3076923076923077,0.35313275428948937,0.5590151072306659,0.20588235294117652
FHAD1,ENSG00000142621,15.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.1,3,15.0,47,13.1,0.3,0.4,15.0,8,10.2,39,0.8733333333333333,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.037002843787934066,0.037002843787934066,0.0,0.0555972405181715,0.3632895482104792,0.3076923076923077,0.15774365495460096,0.3636260078957775,0.20588235294117652
PLK4,ENSG00000142731,22.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,22.0,3,22.3,47,22.0,1.5,3.4,1.9,8,22.3,39,0.9865470852017937,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|glioma|lung cancer|pancreatic cancer|prostate cancer|skin cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.21297982382966296,0.21297982382966296,0.0,0.18424480572678872,0.4919371134190964,0.3076923076923077,0.25643121754588727,0.4623135704870638,0.20588235294117652
AZIN2,ENSG00000142920,31.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,31.2,3,21.6,47,31.2,6.0,0.5,4.2,8,21.6,39,1.4444444444444444,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1287624466571835,0.1287624466571835,0.0,0.15054917520906091,0.4582414829013686,0.3076923076923077,0.3973780255423181,0.6032603784834947,0.20588235294117652
KIF2C,ENSG00000142945,74.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,74.3,3,36.4,47,74.3,2.5,5.2,2.6,8,36.4,39,2.041208791208791,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.31615938168306607,0.31615938168306607,0.0,0.2611595730220316,0.5688518807143392,0.3076923076923077,0.29064412158955444,0.49652647453073095,0.20588235294117652
BARHL2,ENSG00000143032,2.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.2,3,43.9,47,2.2,0.0,0.0,0.0,8,43.9,39,0.05011389521640092,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.04411613314840773,0.24999848608958425,0.20588235294117652
PROK1,ENSG00000143125,190.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,190.9,3,24.4,47,57.3,190.9,48.5,24.4,8,9.5,39,7.8237704918032795,False,0,0,,,,True,False,31,0,BLCA:TCGA|BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|LIHC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PRAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.12397665205343378,0.12397665205343378,0.0,0.05884989423721818,0.3665422019295259,0.3076923076923077,0.1746584617428607,0.3805408146840372,0.20588235294117652
MAEL,ENSG00000143194,154.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,154.6,3,5.4,47,154.6,0.8,6.3,1.4,8,5.4,39,28.629629629629626,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|OV:TCGA|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005940594059405941,0.005940594059405941,0.0,0.029957670128214813,0.33764997782052253,0.3076923076923077,0.18604020121356646,0.391922554154743,0.20588235294117652
ADCY10,ENSG00000143199,17.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,17.1,3,5.9,47,17.1,0.1,0.1,0.9,8,5.9,39,2.898305084745763,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|COAD:validation|GBM:validation|LIHC:TCGA|LIHC:validation|LUSC:TCGA|LUSC:validation|READ:validation|TGCT:TCGA,endometrial cancer|glioma|pancreatic cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009900990099009901,0.009900990099009901,0.0,0.01000691534800472,0.31769922304031245,0.3076923076923077,0.10902225627330034,0.3149046092144768,0.20588235294117652
NUF2,ENSG00000143228,52.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,True,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal RNA exceeds its applicable local category/IHC ceiling; Normal-cell RNA crosses a source-specific review trigger; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,52.0,3,28.0,47,52.0,1.6,4.5,1.7,8,28.0,39,1.8571428571428572,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2766761095372994,0.2766761095372994,0.0,0.21882277029655106,0.5265150779888588,0.3076923076923077,0.24195452435503984,0.44783687729621635,0.20588235294117652
ISG20L2,ENSG00000143319,93.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,93.0,3,18.0,47,93.0,13.3,11.5,12.5,8,18.0,39,5.166666666666667,False,0,0,,,,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.5428551136506801,0.5428551136506801,0.0,0.4559141508750468,0.7636064585673545,0.3076923076923077,0.6645587818139006,0.8704411347550771,0.20588235294117652
LHX9,ENSG00000143355,18.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,18.3,3,3.6,47,2.2,18.3,0.0,0.1,8,3.6,39,5.083333333333333,False,1,0,Cancer-germline,10.1038/s41388-018-0357-2,Bruggeman2018_GC,True,True,31,20,BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:validation|TGCT:TCGA|UCEC:TCGA,cervical cancer|colorectal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.07110271064639577,0.2769850635875723,0.20588235294117652
C1orf56,ENSG00000143443,74.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,74.4,3,9.9,47,74.4,5.7,1.1,6.2,8,9.9,39,7.515151515151516,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.274382533174259,0.274382533174259,0.0,0.248790147919917,0.5564824556122248,0.3076923076923077,0.5231993624190194,0.729081715360196,0.20588235294117652
OAZ3,ENSG00000143450,189.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,189.5,3,8.4,47,189.5,0.2,0.5,8.4,8,7.5,39,22.55952380952381,False,4,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.11006078793683449,0.11006078793683449,0.0,0.16324539523902457,0.4709377029313323,0.3076923076923077,0.2988653833471369,0.5047477362883135,0.20588235294117652
DTL,ENSG00000143476,13.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.3,3,14.4,47,13.3,0.9,3.8,1.8,8,14.4,39,0.9236111111111112,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2115216945970654,0.2115216945970654,0.0,0.15141644130126097,0.4591087489935687,0.3076923076923077,0.18373306689517982,0.38961541983635634,0.20588235294117652
DYRK3,ENSG00000143479,46.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,46.5,3,13.0,47,46.5,5.3,1.1,5.5,8,13.0,39,3.576923076923077,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.29640935361300286,0.29640935361300286,0.0,0.21757762819581067,0.5252699358881183,0.3076923076923077,0.48905723359026665,0.6949395865314432,0.20588235294117652
ABHD1,ENSG00000143994,21.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,21.0,3,3.2,47,21.0,0.3,0.0,0.6,8,3.2,39,6.5625,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:TCGA|BRCA:validation|COAD:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PRAD:TCGA|READ:validation,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0294923255319295,0.0294923255319295,0.0,0.04177885204875937,0.3494711597410671,0.3076923076923077,0.13866912689769062,0.34455147983886714,0.20588235294117652
CCDC150,ENSG00000144395,4.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.8,3,2.5,47,4.8,0.0,0.1,0.1,8,2.5,39,1.92,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Jamin2021_core|Wang2016_CT,True,True,31,20,BRCA:validation|CESC:TCGA|COAD:validation|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUSC:validation|OV:validation|PAAD:validation|READ:validation|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|liver cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.024122412241224127,0.024122412241224127,0.0,0.008745881300085426,0.3164381889923931,0.3076923076923077,0.08133206662618427,0.28721441956736077,0.20588235294117652
LYAR,ENSG00000145220,99.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,99.1,3,23.8,47,99.1,12.0,10.7,10.9,8,23.8,39,4.163865546218487,False,0,0,,,,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.5316599271634092,0.5316599271634092,0.0,0.4415135061307432,0.7492058138230508,0.3076923076923077,0.6630243227684056,0.8689066757095821,0.20588235294117652
ROPN1L,ENSG00000145491,314.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,314.0,3,26.5,47,314.0,0.2,0.2,26.5,8,11.0,39,11.849056603773585,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Wang2016_CT,True,True,31,20,BRCA:TCGA|BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PRAD:TCGA|SKCM:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09605489578482314,0.09605489578482314,0.0,0.019618546885865763,0.3273108545781735,0.3076923076923077,0.2395734007915346,0.4454557537327111,0.20588235294117652
HAPLN1,ENSG00000145681,72.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,72.4,3,10.7,47,0.0,2.4,72.4,0.9,8,10.7,39,6.766355140186917,False,0,0,,,,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,melanoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013668379973348565,0.013668379973348565,0.0,0.17576599710904137,0.4834583048013491,0.3076923076923077,0.15398046904639195,0.35986282198756847,0.20588235294117652
SPATA9,ENSG00000145757,26.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,26.0,3,1.0,47,26.0,0.4,0.2,0.2,8,1.0,39,26.0,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BRCA:validation|GBM:validation|LIHC:validation|PAAD:validation|SKCM:TCGA|THCA:TCGA,breast cancer|colorectal cancer|glioma|pancreatic cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03177589252137884,0.03177589252137884,0.0,0.008745881300085426,0.3164381889923931,0.3076923076923077,0.03746775389997896,0.2433501068411555,0.20588235294117652
TIMD4,ENSG00000145850,140.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,140.0,3,53.9,47,140.0,0.1,4.8,1.2,8,53.9,39,2.5974025974025974,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|lung cancer|prostate cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.3680879034664912,0.3680879034664912,0.0,0.1293098450466209,0.4370021527389286,0.3076923076923077,0.26098255000834114,0.46686490294951766,0.20588235294117652
TCTE1,ENSG00000146221,29.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,29.2,3,14.0,47,29.2,0.4,1.8,14.0,8,7.6,39,2.085714285714286,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|KICH:TCGA|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|OV:TCGA|OV:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.019385972210666447,0.019385972210666447,0.0,0.012488304926168491,0.3201806126184762,0.3076923076923077,0.14750913042182803,0.3533914833630045,0.20588235294117652
IRAK1BP1,ENSG00000146243,4.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.8,3,5.4,47,3.8,2.9,1.1,4.3,8,5.4,39,0.7037037037037036,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|renal cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.18753139219640064,0.18753139219640064,0.0,0.16489816005822094,0.47259046775052865,0.3076923076923077,0.39269852109938813,0.5985808740405647,0.20588235294117652
MTFR2,ENSG00000146410,6.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.8,3,16.1,47,6.8,0.7,1.7,0.9,8,16.1,39,0.42236024844720493,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|colorectal cancer|endometrial cancer|liver cancer|ovarian cancer|pancreatic cancer|prostate cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.16190770174771482,0.16190770174771482,0.0,0.14631640956053196,0.45400871725283964,0.3076923076923077,0.2291427996349447,0.4350251525761212,0.20588235294117652
PNLDC1,ENSG00000146453,7.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.9,3,3.6,47,7.9,1.2,0.0,1.8,8,3.6,39,2.1944444444444446,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1371/journal.pgen.1011734,Chang2019_TGCT|Loriot2025_S2|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|GBM:validation|HNSC:TCGA|LIHC:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,pancreatic cancer|renal cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03763883175647882,0.03763883175647882,0.0,0.01717589875310658,0.3248682064454143,0.3076923076923077,0.10341120531253793,0.30929355825371446,0.20588235294117652
CDCA5,ENSG00000146670,36.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,36.8,3,52.7,47,36.8,1.8,6.3,2.7,8,52.7,39,0.698292220113852,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.3177391409953958,0.3177391409953958,0.0,0.25594756921894324,0.563639876911251,0.3076923076923077,0.3253933243664506,0.531275677307627,0.20588235294117652
RAB41,ENSG00000147127,3.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.9,3,56.0,47,3.9,0.2,0.0,0.2,8,56.0,39,0.06964285714285715,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.015648577993150545,0.015648577993150545,0.0,0.011147850915169795,0.3188401586074775,0.3076923076923077,0.11427865002332356,0.32016100296450006,0.20588235294117652
GPC3,ENSG00000147257,689.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,689.9,3,119.1,47,3.4,59.9,689.9,70.3,8,119.1,39,5.7926112510495384,False,0,0,,,,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,Oncofetal,Membership support,Reviewed reproductive/developmental and tumor association supports biological membership; not a safety or approval claim.,https://pubmed.ncbi.nlm.nih.gov/15920546/,Normal adult liver results cannot be generalized to all tissues; the source reports a positive regenerative focus.,Locus,True,True,False,True,True,False,Established,Cancer-placental|Oncofetal,Reviewed reproductive/developmental and tumor association,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.6053580172923847,0.6053580172923847,0.0,0.40987464691440045,0.7175669546067082,0.3076923076923077,0.5857071396292965,0.7915894925704731,0.20588235294117652
FATE1,ENSG00000147378,232.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,232.3,3,2.2,47,232.3,0.3,0.0,0.3,8,2.2,39,105.5909090909091,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|CESC:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|SKCM:TCGA|TGCT:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0590390322193846,0.0590390322193846,0.0,0.0137105975286832,0.3214029052209909,0.3076923076923077,0.08334619932203494,0.2892285522632114,0.20588235294117652
DNAJC5B,ENSG00000147570,63.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,63.6,3,7.5,47,63.6,0.1,0.1,0.6,8,7.5,39,8.48,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.05218666406684034,0.05218666406684034,0.0,0.12158227848387472,0.4292745861761824,0.3076923076923077,0.15608546593805958,0.3619678188792361,0.20588235294117652
NR6A1,ENSG00000148200,22.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,22.2,3,5.2,47,22.2,0.3,2.2,1.3,8,5.2,39,4.269230769230769,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.12575205198629524,0.12575205198629524,0.0,0.10120148904377936,0.40889379673608706,0.3076923076923077,0.33932142905582763,0.5452037819970041,0.20588235294117652
HTR7,ENSG00000148680,8.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.5,3,12.7,47,8.5,0.1,0.3,0.6,8,12.7,39,0.6692913385826772,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|PAAD:TCGA|PAAD:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,carcinoid|endometrial cancer|liver cancer|prostate cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04476920551469184,0.04476920551469184,0.0,0.12137126136155753,0.4290635690538652,0.3076923076923077,0.10790984714805676,0.31379220008923325,0.20588235294117652
LRRC27,ENSG00000148814,73.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,73.5,3,15.3,47,73.5,6.0,2.6,12.6,8,15.3,39,4.803921568627451,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2777908505904339,0.2777908505904339,0.0,0.24376133977197845,0.5514536474642862,0.3076923076923077,0.5328355726456581,0.7387179255868346,0.20588235294117652
PAOX,ENSG00000148832,26.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,26.6,3,7.5,47,26.6,2.3,0.1,3.2,8,7.5,39,3.546666666666667,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.16654014276328752,0.16654014276328752,0.0,0.14307857232579568,0.4507708800181034,0.3076923076923077,0.371312409432763,0.5771947623739395,0.20588235294117652
ADAM12,ENSG00000148848,130.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,130.4,3,12.7,47,0.7,6.6,130.4,12.7,8,9.0,39,10.267716535433072,False,0,1,Cancer-placental|Cancer-reproductive,10.1038/s41467-020-19141-w|10.1038/s41467-021-22695-y,Bradley2020_CPA|Gong2021_placenta_PC|Gong2021_reproductive_PC,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1487282529152506,0.1487282529152506,0.0,0.0985288708361105,0.4062211785284182,0.3076923076923077,0.17499679290336728,0.3808791458445438,0.20588235294117652
KLHL35,ENSG00000149243,9.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.0,3,10.4,47,9.0,0.4,0.0,0.9,8,10.4,39,0.8653846153846153,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.05745939689522728,0.05745939689522728,0.0,0.033387874312030226,0.34108018200433793,0.3076923076923077,0.20026155874388885,0.40614391168506536,0.20588235294117652
OOSP2,ENSG00000149507,17.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,17.4,3,0.0,47,17.4,1.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_testis_biased,False,False,29,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CCDC15,ENSG00000149548,10.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.2,3,3.8,47,10.2,0.7,0.7,2.7,8,3.8,39,2.6842105263157894,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Jamin2021_core|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.11645011052235164,0.11645011052235164,0.0,0.09116867858094062,0.39886098627324834,0.3076923076923077,0.1866871720116995,0.392569524952876,0.20588235294117652
CHEK1,ENSG00000149554,29.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.0,3,29.4,47,9.0,2.1,4.7,29.4,8,26.0,39,0.30612244897959184,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2663467124970132,0.2663467124970132,0.0,0.3079167353148661,0.6156090430071738,0.3076923076923077,0.3837687231617953,0.5896510761029718,0.20588235294117652
DUSP15,ENSG00000149599,204.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,204.7,3,48.7,47,204.7,5.0,0.7,8.9,8,48.7,39,4.2032854209445585,False,0,0,,,,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.19559982805161963,0.19559982805161963,0.0,0.15670904279691664,0.4644013504892244,0.3076923076923077,0.42728757533213585,0.6331699282733123,0.20588235294117652
CNBD2,ENSG00000149646,25.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,25.2,3,22.9,47,25.2,3.9,1.6,12.2,8,22.9,39,1.1004366812227075,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.3035233161038046,0.3035233161038046,0.0,0.28832111834075075,0.5960134260330585,0.3076923076923077,0.5609324521880981,0.7668148051292746,0.20588235294117652
CABLES2,ENSG00000149679,30.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,30.2,3,13.8,47,30.2,4.1,2.7,4.6,8,13.8,39,2.1884057971014492,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.28979705122824456,0.28979705122824456,0.0,0.26373758103926986,0.5714298887315776,0.3076923076923077,0.5359161438073347,0.7417984967485112,0.20588235294117652
TLCD3B,ENSG00000149926,101.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,101.9,3,85.2,47,101.9,0.0,0.0,0.2,8,85.2,39,1.1960093896713615,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02770178448687477,0.02770178448687477,0.0,0.044818821434882604,0.3525111291271903,0.3076923076923077,0.3036255550007736,0.5095079079419501,0.20588235294117652
SPATA4,ENSG00000150628,135.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,135.4,3,8.4,47,135.4,0.2,0.0,8.4,8,2.2,39,16.11904761904762,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:TCGA|BRCA:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|OV:TCGA|OV:validation|PRAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.029566404916353706,0.029566404916353706,0.0,0.020724494085149824,0.3284168017774575,0.3076923076923077,0.16968437932253938,0.3755667322637159,0.20588235294117652
FSIP1,ENSG00000150667,7.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.0,3,10.6,47,7.0,0.1,0.3,1.2,8,10.6,39,0.6603773584905661,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUSC:TCGA|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.05335910931954659,0.05335910931954659,0.0,0.11448476181148882,0.4221770695037965,0.3076923076923077,0.11970533690936465,0.32558768985054115,0.20588235294117652
PIH1D2,ENSG00000150773,64.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,64.5,3,14.4,47,64.5,1.1,0.7,14.4,8,12.0,39,4.479166666666667,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.11847098203635922,0.11847098203635922,0.0,0.10126315640226491,0.4089554640945726,0.3076923076923077,0.30968619840068234,0.5155685513418589,0.20588235294117652
TEX12,ENSG00000150783,20.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,20.1,3,8.4,47,20.1,0.1,0.0,0.4,8,8.4,39,2.392857142857143,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BRCA:validation|GBM:validation|PAAD:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.026791319535034254,0.026791319535034254,0.0,0.02536772498176478,0.33306003267407247,0.3076923076923077,0.0887708471379871,0.2946532000791636,0.20588235294117652
RAD9B,ENSG00000151164,11.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11.0,3,0.8,47,11.0,0.7,0.1,0.5,8,0.8,39,13.75,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRP:TCGA|LIHC:validation|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|colorectal cancer|endometrial cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.027185930384102858,0.027185930384102858,0.0,0.029087822237559863,0.33678012992986756,0.3076923076923077,0.11189564319359716,0.31777799613477364,0.20588235294117652
TEX30,ENSG00000151287,119.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,119.2,3,69.5,47,119.2,7.8,14.4,69.5,8,38.8,39,1.7151079136690648,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.4432636012691199,0.4432636012691199,0.0,0.35412420665516037,0.6618165143474681,0.3076923076923077,0.6381780662349137,0.8440604191760902,0.20588235294117652
MIPOL1,ENSG00000151338,8.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.2,3,7.5,47,8.2,5.0,1.7,7.5,8,6.7,39,1.0933333333333333,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.17916592108744023,0.17916592108744023,0.0,0.21805856487260888,0.5257508725649166,0.3076923076923077,0.4169034806737011,0.6227858336148776,0.20588235294117652
SLC25A31,ENSG00000151475,45.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,45.9,3,0.1,47,45.9,0.0,0.0,0.0,8,0.1,39,458.99999999999994,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,TGCT:TCGA,glioma,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0017507002801120447,0.20763305322128855,0.20588235294117652
ANKAR,ENSG00000151687,5.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,True,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.6,3,0.6,47,5.6,0.2,0.3,0.6,8,0.6,39,9.333333333333334,False,1,0,Cancer-germline,10.1038/s41388-018-0357-2,Bruggeman2018_GC,True,True,31,20,BRCA:validation|COAD:validation|GBM:validation|KIRC:validation|LIHC:validation|OV:validation|PAAD:validation|READ:validation,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Antibody concern|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.028943126581816782,0.028943126581816782,0.0,0.03577599179488697,0.3434682994871947,0.3076923076923077,0.07648845187208358,0.2823708048132601,0.20588235294117652
CENPU,ENSG00000151725,28.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,28.6,3,61.8,47,28.6,1.3,4.7,5.5,8,61.8,39,0.46278317152103565,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.31575845302058275,0.31575845302058275,0.0,0.27736776883198544,0.5850600765242931,0.3076923076923077,0.3337786127244095,0.539660965665586,0.20588235294117652
PABPC3,ENSG00000151846,35.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,35.7,3,0.8,47,35.7,0.5,0.0,0.5,8,0.8,39,44.625,False,6,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|GBM:validation|KIRP:TCGA|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|ovarian cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.025059254471019178,0.025059254471019178,0.0,0.02703179173767409,0.3347240994299818,0.3076923076923077,0.05905741743337651,0.264939770374553,0.20588235294117652
TUBA3E,ENSG00000152086,170.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,170.4,3,51.5,47,170.4,0.2,0.5,3.8,8,51.5,39,3.30873786407767,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|KIRC:TCGA|KIRC:validation|LUSC:TCGA|PRAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|colorectal cancer|endometrial cancer|glioma|head and neck cancer|melanoma|prostate cancer|skin cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.06975477106730542,0.27563712400848195,0.20588235294117652
POU4F1,ENSG00000152192,0.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.9,3,2.5,47,0.9,0.0,0.2,0.0,8,2.5,39,0.36,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|READ:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,carcinoid,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.01308411214953271,0.01308411214953271,0.0,0.007178193811232904,0.3148705015035406,0.3076923076923077,0.04831858962293745,0.25420094256411396,0.20588235294117652
GRID2,ENSG00000152208,33.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,33.0,3,11.2,47,33.0,1.6,0.0,0.3,8,11.2,39,2.9464285714285716,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,GBM:TCGA|GBM:validation|KICH:TCGA|OV:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0037831021437578823,0.3114754098360656,0.3076923076923077,0.1174129921697432,0.32329534511091973,0.20588235294117652
ATG10,ENSG00000152348,10.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.0,3,11.2,47,10.0,4.1,4.5,7.6,8,11.2,39,0.8928571428571429,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|lung cancer|lymphoma|ovarian cancer|pancreatic cancer|renal cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.353941766149124,0.353941766149124,0.0,0.303599545749813,0.6112918534421208,0.3076923076923077,0.5499553706150626,0.7558377235562391,0.20588235294117652
SUV39H2,ENSG00000152455,38.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,38.1,3,5.9,47,38.1,3.3,3.7,3.8,8,5.9,39,6.4576271186440675,False,1,0,Cancer-germline,10.1038/s41388-018-0357-2,Bruggeman2018_GC,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1915057134193951,0.1915057134193951,0.0,0.1928856288220902,0.5005779365143979,0.3076923076923077,0.3846781483441283,0.5905605012853048,0.20588235294117652
OLAH,ENSG00000152463,26.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,26.1,3,8.7,47,26.1,0.2,3.1,5.3,8,8.7,39,3.0000000000000004,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:validation|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,liver cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.14012834529307594,0.14012834529307594,0.0,0.06675381649462249,0.3744461241869302,0.3076923076923077,0.16517699741902395,0.37105935036020044,0.20588235294117652
TRIM36,ENSG00000152503,169.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,169.2,3,42.9,47,169.2,3.1,1.1,9.7,8,42.9,39,3.9440559440559437,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.047374054541583874,0.047374054541583874,0.0,0.14091861025222654,0.4486109179445342,0.3076923076923077,0.3580206842311164,0.5639030371722928,0.20588235294117652
CATSPER3,ENSG00000152705,28.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,28.8,3,2.9,47,28.8,0.8,0.2,0.9,8,2.9,39,9.931034482758621,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.054739652870493996,0.054739652870493996,0.0,0.07146105875169831,0.379153366444006,0.3076923076923077,0.2493419923361465,0.45522434527732303,0.20588235294117652
CENPH,ENSG00000153044,28.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,28.8,3,33.2,47,28.8,5.2,5.0,7.5,8,33.2,39,0.8674698795180722,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.38527052398020145,0.38527052398020145,0.0,0.3154961633286,0.6231884710209077,0.3076923076923077,0.4664250698228479,0.6723074227640244,0.20588235294117652
FAM81B,ENSG00000153347,81.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,81.1,3,60.6,47,81.1,0.1,0.0,46.7,8,60.6,39,1.3382838283828382,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734,Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Loriot2025_S2|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.033411449614998326,0.033411449614998326,0.0,0.02445941155618575,0.33215171924849346,0.3076923076923077,0.2369690480328346,0.4428514009740111,0.20588235294117652
TEX29,ENSG00000153495,50.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,50.4,3,12.0,47,50.4,0.4,0.1,0.9,8,12.0,39,4.2,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,0,CESC:TCGA|GBM:TCGA|GBM:validation|OV:validation|PAAD:validation|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04180423690926143,0.04180423690926143,0.0,0.027634775900854086,0.33532708359316177,0.3076923076923077,0.17408148010959024,0.37996383305076675,0.20588235294117652
SPMIP4,ENSG00000153790,63.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,63.6,3,7.6,47,63.6,4.7,1.3,3.7,8,7.6,39,8.368421052631579,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.255965114771577,0.255965114771577,0.0,0.2520970318585218,0.5597893395508295,0.3076923076923077,0.4253045057884351,0.6311868587296117,0.20588235294117652
CABYR,ENSG00000154040,295.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,295.1,3,12.7,47,295.1,2.0,0.9,6.5,8,12.7,39,23.236220472440948,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.12198333136548241,0.12198333136548241,0.0,0.11480739291711882,0.42249970060942654,0.3076923076923077,0.3735661190818694,0.579448472023046,0.20588235294117652
DNAAF1,ENSG00000154099,43.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,43.9,3,23.7,47,43.9,0.4,0.2,22.0,8,23.7,39,1.8523206751054853,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,30,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|SKCM:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,ovarian cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.046976509409520424,0.046976509409520424,0.0,0.01953912692278636,0.3272314346150941,0.3076923076923077,0.22952611465573436,0.4354084675969109,0.20588235294117652
WNT3A,ENSG00000154342,15.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.1,3,3.6,47,0.0,0.0,15.1,1.3,8,3.6,39,4.194444444444445,False,0,0,,,,True,False,31,0,BLCA:TCGA|BRCA:validation|CESC:TCGA|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|PRAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.030508474576271184,0.030508474576271184,0.0,0.022283489852983798,0.3299757975452915,0.3076923076923077,0.04061624649859944,0.24649859943977595,0.20588235294117652
CFAP210,ENSG00000154479,77.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,77.8,3,45.9,47,77.8,0.6,0.1,14.4,8,45.9,39,1.6949891067538125,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,29,20,BRCA:TCGA|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|liver cancer|lung cancer|melanoma|pancreatic cancer|prostate cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06527263814352649,0.06527263814352649,0.0,0.03740694789081886,0.3450992555831266,0.3076923076923077,0.2761038169463815,0.481986169887558,0.20588235294117652
SRSF12,ENSG00000154548,11.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11.1,3,4.2,47,11.1,1.5,0.3,1.0,8,4.2,39,2.642857142857143,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,30,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.046559998159084404,0.046559998159084404,0.0,0.04518829089566755,0.35288059858797527,0.3076923076923077,0.21764783563748732,0.42353018857866387,0.20588235294117652
CHODL,ENSG00000154645,30.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,30.1,3,13.7,47,30.1,1.0,1.9,5.4,8,13.7,39,2.1970802919708032,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.22416929750159664,0.22416929750159664,0.0,0.10724034228351692,0.41493264997582463,0.3076923076923077,0.24642257033839646,0.45230492327957295,0.20588235294117652
EME1,ENSG00000154920,6.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.6,3,6.2,47,5.6,0.6,1.4,6.2,8,4.3,39,0.9032258064516128,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0966258062858171,0.0966258062858171,0.0,0.07016497828325272,0.37785728597556045,0.3076923076923077,0.13764495190326392,0.34352730484444044,0.20588235294117652
AK9,ENSG00000155085,16.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.1,3,15.5,47,16.1,3.4,2.9,7.6,8,15.5,39,1.038709677419355,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.32584497621147307,0.32584497621147307,0.0,0.2945800025055883,0.602272310197896,0.3076923076923077,0.5470822145540751,0.7529645674952516,0.20588235294117652
PPM1J,ENSG00000155367,62.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,62.0,3,73.1,47,62.0,2.2,0.5,20.2,8,73.1,39,0.8481532147742818,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|colorectal cancer|glioma|melanoma|ovarian cancer|prostate cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.26403341161105137,0.26403341161105137,0.0,0.22952362715019603,0.5372159348425037,0.3076923076923077,0.4445103925807179,0.6503927455218944,0.20588235294117652
LRGUK,ENSG00000155530,5.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.0,3,3.9,47,5.0,0.1,0.1,3.9,8,3.2,39,1.2820512820512822,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|liver cancer|lymphoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.036414565826330535,0.036414565826330535,0.0,0.01962582021972658,0.3273181279120343,0.3076923076923077,0.12687037907626142,0.33275273201743794,0.20588235294117652
XAGE2,ENSG00000155622,192.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,192.5,3,5.5,47,0.5,0.0,192.5,0.1,8,5.5,39,35.0,False,0,0,Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_placenta_PC|Gong2021_reproductive_PC,True,True,31,20,BLCA:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|READ:TCGA|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005901766647252961,0.005901766647252961,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.06669213139801375,0.2725744843391903,0.20588235294117652
OTOA,ENSG00000155719,3.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.9,3,2.0,47,3.9,0.0,0.0,0.2,8,2.0,39,1.95,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BRCA:validation|GBM:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|PAAD:TCGA|PAAD:validation|SKCM:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04113877407158192,0.04113877407158192,0.0,0.007525525769840948,0.31521783346214866,0.3076923076923077,0.04552651099965678,0.2514088639408333,0.20588235294117652
FLACC1,ENSG00000155749,16.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.6,3,8.7,47,16.6,0.3,0.8,8.0,8,8.7,39,1.9080459770114946,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09181871514860898,0.09181871514860898,0.0,0.08322615117872754,0.39091845887103527,0.3076923076923077,0.3304554293603184,0.536337782301495,0.20588235294117652
C2CD6,ENSG00000155754,38.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,38.7,3,1.2,47,38.7,0.8,0.1,0.3,8,1.2,39,32.25000000000001,False,4,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,0,BLCA:TCGA|CESC:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|SKCM:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.017261348776387075,0.017261348776387075,0.0,0.006264491721921653,0.3139567994142294,0.3076923076923077,0.11188635381459214,0.3177687067557686,0.20588235294117652
SAXO1,ENSG00000155875,37.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,37.4,3,0.4,47,37.4,0.1,0.0,0.4,8,0.2,39,93.49999999999999,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,29,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005901766647252961,0.005901766647252961,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.011172650878533232,0.21705500381970974,0.20588235294117652
PHKG2,ENSG00000156873,126.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,126.5,3,29.6,47,126.5,8.1,7.5,14.3,8,29.6,39,4.273648648648648,False,0,0,,,,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.5418043148550858,0.5418043148550858,0.0,0.45572874917838135,0.7634210568706891,0.3076923076923077,0.6864685938852481,0.8923509468264246,0.20588235294117652
BUB1B,ENSG00000156970,21.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,21.6,3,34.8,47,21.6,1.0,3.3,1.7,8,34.8,39,0.6206896551724139,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.26947337488382267,0.26947337488382267,0.0,0.20540533991854834,0.5130976476108561,0.3076923076923077,0.19869236594397094,0.40457471888514746,0.20588235294117652
SHCBP1L,ENSG00000157060,111.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,111.3,3,0.0,47,111.3,0.0,0.0,0.0,8,0.0,39,,True,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,30,20,CESC:TCGA|PAAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CFAP107,ENSG00000157330,47.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,47.5,3,45.3,47,47.5,0.0,0.1,25.8,8,45.3,39,1.0485651214128036,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.020993260429090804,0.020993260429090804,0.0,0.0037831021437578823,0.3114754098360656,0.3076923076923077,0.10470767429430636,0.3105900272354829,0.20588235294117652
ARMC12,ENSG00000157343,62.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,62.4,3,10.9,47,62.4,2.9,0.2,5.7,8,10.9,39,5.724770642201834,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PRAD:TCGA|READ:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1735156410101889,0.1735156410101889,0.0,0.08251760078264105,0.39020990847494874,0.3076923076923077,0.35833616612621216,0.5642185190673887,0.20588235294117652
CCNB2,ENSG00000157456,67.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,67.4,3,73.6,47,67.4,4.6,11.0,5.4,8,73.6,39,0.9157608695652175,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|lymphoma|ovarian cancer|pancreatic cancer|skin cancer|stomach cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.38922323255877633,0.38922323255877633,0.0,0.32512868040039156,0.6328209880926993,0.3076923076923077,0.3223663096073278,0.5282486625485043,0.20588235294117652
LCA5L,ENSG00000157578,107.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,107.2,3,10.5,47,107.2,0.8,0.3,7.5,8,10.5,39,10.20952380952381,False,5,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,glioma|head and neck cancer|liver cancer|melanoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0968785491484167,0.0968785491484167,0.0,0.08240375513333437,0.3900960628256421,0.3076923076923077,0.27807936313782705,0.48396171607900357,0.20588235294117652
CDC25C,ENSG00000158402,17.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,17.5,3,8.6,47,17.5,0.6,1.2,0.7,8,8.6,39,2.0348837209302326,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Jamin2021_core|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.13789749595223488,0.13789749595223488,0.0,0.12111475216116979,0.4288070598534775,0.3076923076923077,0.13959901923000204,0.3454813721711786,0.20588235294117652
RIBC1,ENSG00000158423,38.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,38.2,3,27.4,47,38.2,2.6,0.3,26.6,8,27.4,39,1.394160583941606,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.13083254276253953,0.13083254276253953,0.0,0.09993716482743586,0.4076294725197436,0.3076923076923077,0.36757272166476934,0.5734550746059459,0.20588235294117652
CPA5,ENSG00000158525,32.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,32.7,3,2.2,47,32.7,0.0,0.6,0.1,8,2.2,39,14.863636363636363,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09115035826704103,0.09115035826704103,0.0,0.02726655437878641,0.3349588620710941,0.3076923076923077,0.07465524671407024,0.28053759965524677,0.20588235294117652
IGF2BP1,ENSG00000159217,5.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.3,3,1.2,47,4.6,0.0,5.3,0.0,8,1.2,39,4.416666666666667,False,4,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,colorectal cancer|lung cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline|Cancer-placental,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.003663003663003663,0.31135531135531136,0.3076923076923077,0.027661064425770307,0.23354341736694684,0.20588235294117652
GIP,ENSG00000159224,0.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.5,3,251.8,47,0.5,0.0,0.1,0.1,8,251.8,39,0.0019857029388403494,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,LUAD:TCGA|PAAD:TCGA|PAAD:validation|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.01774455053143578,0.32543685822374346,0.3076923076923077,0.060362342361837434,0.266244695303014,0.20588235294117652
M1AP,ENSG00000159374,6.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.3,3,2.4,47,6.3,0.2,0.1,1.6,8,2.4,39,2.625,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03505925488526662,0.03505925488526662,0.0,0.02901071395663494,0.33670302164894267,0.3076923076923077,0.11288013385200085,0.31876248679317737,0.20588235294117652
DRC7,ENSG00000159625,44.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,44.7,3,20.4,47,44.7,0.2,0.1,20.4,8,12.0,39,2.1911764705882355,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,29,0,BRCA:TCGA|CESC:TCGA|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.011803533294505923,0.011803533294505923,0.0,0.011779163006106028,0.31947147069841375,0.3076923076923077,0.15687754028624915,0.36275989322742563,0.20588235294117652
SPMIP8,ENSG00000159648,13.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.8,3,2.1,47,13.8,0.5,0.0,0.5,8,2.1,39,6.571428571428571,False,0,0,,,,True,False,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|HNSC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|OV:TCGA|OV:validation|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04457290648850982,0.04457290648850982,0.0,0.018781503774271374,0.32647381146657906,0.3076923076923077,0.049598100109609064,0.2554804530507856,0.20588235294117652
LRRC36,ENSG00000159708,34.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,34.3,3,4.8,47,34.3,0.1,5.9,2.9,8,4.8,39,7.145833333333333,False,1,0,Cancer-germline,10.1371/journal.pgen.1011734,Loriot2025_S2,True,False,31,20,BRCA:validation|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:validation|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005940594059405941,0.005940594059405941,0.0,0.020539522309037828,0.32823183000134554,0.3076923076923077,0.06796567731952116,0.2738480302606977,0.20588235294117652
C16orf86,ENSG00000159761,38.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,38.7,3,10.0,47,38.7,2.0,1.1,3.4,8,10.0,39,3.87,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.18771294627655652,0.18771294627655652,0.0,0.17226895524670616,0.47996126293901387,0.3076923076923077,0.40238390369345084,0.6082662566346273,0.20588235294117652
HSF2BP,ENSG00000160207,23.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,23.4,3,2.4,47,23.4,1.0,0.9,0.6,8,2.4,39,9.75,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.028943126581816782,0.028943126581816782,0.0,0.03372025954397676,0.3414125672362845,0.3076923076923077,0.12746813013894545,0.33335048308012194,0.20588235294117652
CLDND2,ENSG00000160318,43.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,43.7,3,9.5,47,43.7,4.5,0.8,4.2,8,9.5,39,4.6000000000000005,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|endometrial cancer|lung cancer|ovarian cancer|pancreatic cancer|stomach cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.24377450530044803,0.24377450530044803,0.0,0.20923724667121377,0.5169295543635215,0.3076923076923077,0.5026340049724184,0.7085163579135949,0.20588235294117652
HIPK4,ENSG00000160396,17.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,17.6,3,8.8,47,17.6,0.2,0.0,0.4,8,8.8,39,2.0,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:validation|KICH:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009823335274703943,0.009823335274703943,0.0,0.013363265570075156,0.3210555732623829,0.3076923076923077,0.07262527696271588,0.2785076299038924,0.20588235294117652
COX6B2,ENSG00000160471,88.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,88.0,3,6.5,47,88.0,0.5,0.2,1.2,8,6.5,39,13.538461538461538,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.10808407879198462,0.10808407879198462,0.0,0.11204210755844532,0.41973441525075306,0.3076923076923077,0.11246963755363255,0.31835199049480906,0.20588235294117652
LRRC71,ENSG00000160838,24.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,24.7,3,12.0,47,24.7,0.1,0.1,12.0,8,11.1,39,2.058333333333333,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1371/journal.pgen.1011734,Chang2019_TGCT|Loriot2025_S2|Wang2016_CT,True,False,30,0,GBM:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|OV:TCGA|OV:validation|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.00788196466705494,0.00788196466705494,0.0,0.0,0.3076923076923077,0.3076923076923077,0.08261579473526326,0.2884981476764398,0.20588235294117652
LY6K,ENSG00000160886,35.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,True,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal RNA exceeds its applicable local category/IHC ceiling; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,35.0,3,12.1,47,35.0,0.7,2.3,4.9,8,12.1,39,2.8925619834710745,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.17969520973305758,0.17969520973305758,0.0,0.11219022613237076,0.41988253382467844,0.3076923076923077,0.2296907116152642,0.43557306455644074,0.20588235294117652
TEKTL1,ENSG00000160994,15.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.0,3,0.2,47,15.0,0.0,0.0,0.0,8,0.2,39,75.0,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,False,True,31,20,,testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0053475935828877,0.2112299465240642,0.20588235294117652
LRWD1,ENSG00000161036,267.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,267.6,3,26.8,47,267.6,9.1,3.0,13.4,8,26.8,39,9.985074626865671,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.4973388051557818,0.4973388051557818,0.0,0.3656751893801548,0.6733674970724626,0.3076923076923077,0.6641269129243843,0.8700092658655608,0.20588235294117652
FBXL13,ENSG00000161040,3.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.8,3,4.9,47,3.8,1.1,0.2,2.3,8,4.9,39,0.7755102040816325,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,liver cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0546724414648943,0.0546724414648943,0.0,0.06568913050229312,0.37338143819460085,0.3076923076923077,0.12387700733759106,0.32975936027876757,0.20588235294117652
KASH5,ENSG00000161609,53.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,53.0,3,11.5,47,53.0,0.0,0.0,0.0,8,11.5,39,4.608695652173913,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,29,20,CESC:TCGA|HNSC:TCGA|OV:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,colorectal cancer|liver cancer|lung cancer|ovarian cancer|pancreatic cancer|renal cancer|skin cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.06501196539559712,0.27089431833677363,0.20588235294117652
AQP5,ENSG00000161798,215.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,215.9,3,604.8,47,215.9,0.2,0.0,16.6,8,604.8,39,0.35697751322751325,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,endometrial cancer|ovarian cancer|pancreatic cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2622217918997838,0.2622217918997838,0.0,0.2344729331473118,0.5421652408396195,0.3076923076923077,0.26817254792311024,0.47405490086428675,0.20588235294117652
CLPB,ENSG00000162129,107.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,107.2,3,10.0,47,107.2,2.4,5.1,3.2,8,10.0,39,10.72,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2727879321526111,0.2727879321526111,0.0,0.2789302935856557,0.5866226012779634,0.3076923076923077,0.561163025282353,0.7670453782235295,0.20588235294117652
SAXO4,ENSG00000162148,91.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,91.2,3,52.0,47,91.2,6.4,4.0,39.2,8,52.0,39,1.7538461538461538,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.3939243428857031,0.3939243428857031,0.0,0.2579699313444137,0.5656622390367214,0.3076923076923077,0.5804090438998354,0.7862913968410119,0.20588235294117652
TTLL10,ENSG00000162571,40.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,40.8,3,10.4,47,40.8,0.0,1.4,10.4,8,2.9,39,3.9230769230769225,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|LUAD:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03125190670327538,0.03125190670327538,0.0,0.019546400256647174,0.3272387079489549,0.3076923076923077,0.10566510011623857,0.3115474530574151,0.20588235294117652
LRRIQ3,ENSG00000162620,19.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,19.8,3,2.1,47,19.8,0.3,0.2,2.1,8,1.9,39,9.428571428571429,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1371/journal.pgen.1011734,Chang2019_TGCT|Loriot2025_S2|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.07646681261146215,0.07646681261146215,0.0,0.04502615794664935,0.35271846563895703,0.3076923076923077,0.13511964195225504,0.3410019948934315,0.20588235294117652
HENMT1,ENSG00000162639,69.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,69.9,3,18.2,47,69.9,8.5,5.4,8.2,8,18.2,39,3.8406593406593412,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,30,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|renal cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.39007056300392884,0.39007056300392884,0.0,0.3070527537156491,0.6147450614079568,0.3076923076923077,0.5199568919582769,0.7258392448994534,0.20588235294117652
SLC9C2,ENSG00000162753,5.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.8,3,0.8,47,5.8,0.2,0.0,0.5,8,0.8,39,7.249999999999999,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,20,GBM:validation|OV:TCGA|OV:validation|PAAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.009438558031908415,0.21532091097308492,0.20588235294117652
KLHDC9,ENSG00000162755,28.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,28.2,3,7.0,47,28.2,0.9,0.0,2.1,8,7.0,39,4.0285714285714285,False,0,0,,,,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.05674116711294073,0.05674116711294073,0.0,0.07092879254592978,0.3786211002382375,0.3076923076923077,0.3073265604744758,0.5132089134156523,0.20588235294117652
LRRC52,ENSG00000162763,16.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.2,3,3.9,47,16.2,0.0,0.0,0.1,8,3.9,39,4.153846153846154,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:validation|KICH:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|OV:TCGA|SKCM:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.034045453929113366,0.34173776162142105,0.3076923076923077,0.05534122740005093,0.26122358034122745,0.20588235294117652
GARIN4,ENSG00000162771,76.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,76.5,3,0.7,47,76.5,0.0,0.0,0.4,8,0.7,39,109.28571428571429,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02088955288778129,0.02088955288778129,0.0,0.0061850717588422515,0.31387737945114996,0.3076923076923077,0.022824149422614896,0.22870650236379142,0.20588235294117652
AXDND1,ENSG00000162779,15.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.3,3,0.4,47,15.3,0.0,0.0,0.4,8,0.3,39,38.25,False,4,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,30,20,COAD:validation|GBM:validation|LIHC:validation|PAAD:validation|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.007484847252166131,0.31517715494447385,0.3076923076923077,0.022509992139148147,0.22839234508032466,0.20588235294117652
TDRD5,ENSG00000162782,21.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,21.2,3,6.4,47,21.2,0.5,0.2,6.4,8,2.3,39,3.3124999999999996,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,liver cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02654182418051438,0.02654182418051438,0.0,0.040985690881010665,0.3486779985733184,0.3076923076923077,0.11216850352226596,0.31805085646344244,0.20588235294117652
SPATA17,ENSG00000162814,9.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.9,3,3.9,47,9.9,0.2,0.2,3.9,8,2.7,39,2.5384615384615388,False,5,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Jamin2021_CT|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.028548515732748175,0.028548515732748175,0.0,0.03751470893039313,0.3452070166227008,0.3076923076923077,0.14564148926191153,0.3515238422030881,0.20588235294117652
WDR64,ENSG00000162843,2.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,True,False,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.3,3,0.1,47,2.3,0.1,0.2,0.0,8,0.1,39,22.999999999999996,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,31,20,,breast cancer|colorectal cancer|endometrial cancer|head and neck cancer|melanoma|ovarian cancer|pancreatic cancer|skin cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Antibody concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.005602240896358543,0.21148459383753507,0.20588235294117652
KLHDC8A,ENSG00000162873,275.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,275.0,3,29.1,47,6.2,275.0,0.0,13.4,8,29.1,39,9.450171821305842,False,0,0,,,,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.07087487903988503,0.07087487903988503,0.0,0.13053913540052572,0.43823144309283346,0.3076923076923077,0.38414129709377043,0.590023650034947,0.20588235294117652
TRIM17,ENSG00000162931,40.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,40.8,3,46.1,47,40.8,3.1,0.2,3.9,8,46.1,39,0.8850325379609544,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1926729349067279,0.1926729349067279,0.0,0.10706592599243876,0.41475823368474646,0.3076923076923077,0.26215336885127843,0.46803572179245495,0.20588235294117652
CCDC138,ENSG00000163006,10.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.6,3,6.2,47,10.6,1.9,1.3,4.2,8,6.2,39,1.7096774193548385,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT|Jamin2021_core,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1666987315715592,0.1666987315715592,0.0,0.15159813594237248,0.4592904436346802,0.3076923076923077,0.34201783157727367,0.5479001845184501,0.20588235294117652
ANKRD30BL,ENSG00000163046,4.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; No source-backed cancer/reproductive candidate nomination,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.1,3,0.0,47,4.1,0.0,0.0,0.0,8,0.0,39,,True,0,0,,,,True,False,30,0,GBM:validation|LIHC:validation|PAAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
TEKT4,ENSG00000163060,13.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.1,3,2.4,47,13.1,0.0,0.0,2.4,8,0.6,39,5.458333333333333,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BRCA:validation|CESC:TCGA|GBM:validation|KICH:TCGA|LUAD:TCGA|LUSC:TCGA|OV:TCGA|OV:validation|PAAD:validation|PRAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|colorectal cancer|endometrial cancer|pancreatic cancer|prostate cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.027957581634052223,0.23383993457522873,0.20588235294117652
SMCP,ENSG00000163206,727.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,727.3,3,1.2,47,727.3,0.3,0.0,0.7,8,1.2,39,606.0833333333334,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,GBM:validation|HNSC:TCGA|LUSC:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009823335274703943,0.009823335274703943,0.0,0.00630517023959647,0.3139974779319042,0.3076923076923077,0.03648220651897122,0.24236455946014773,0.20588235294117652
TDRD10,ENSG00000163239,54.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,54.1,3,10.7,47,54.1,9.8,1.7,6.6,8,10.7,39,5.056074766355141,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:TCGA|BRCA:validation|CESC:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.3454007966607019,0.3454007966607019,0.0,0.15803031509309712,0.4657226227854048,0.3076923076923077,0.39885501712399263,0.6047373700651691,0.20588235294117652
CRYGC,ENSG00000163254,1.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.6,3,0.1,47,1.6,0.0,0.0,0.1,8,0.1,39,16.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,OV:TCGA|OV:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0003501400560224089,0.20623249299719892,0.20588235294117652
CFAP141,ENSG00000163263,29.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,19.1,3,29.5,47,19.1,0.1,0.0,29.5,8,1.7,39,0.6474576271186441,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,0,BRCA:TCGA|BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PRAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.00859079445145019,0.3162831021437579,0.3076923076923077,0.08806104972874529,0.2939434026699218,0.20588235294117652
ABRAXAS1,ENSG00000163322,10.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.5,3,7.8,47,10.5,10.5,2.8,6.2,8,7.8,39,1.3461538461538463,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,False,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.33409416531404273,0.33409416531404273,0.0,0.2519412049035849,0.5596335125958927,0.3076923076923077,0.467205289902285,0.6730876428434616,0.20588235294117652
DCST1,ENSG00000163357,6.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.5,3,3.0,47,6.5,0.1,0.0,0.3,8,3.0,39,2.1666666666666665,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|LIHC:validation|LUAD:TCGA|LUAD:validation|PAAD:validation|READ:validation|SKCM:TCGA,breast cancer|carcinoid|colorectal cancer|glioma|lymphoma|ovarian cancer|pancreatic cancer|prostate cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.052094440213252095,0.052094440213252095,0.0,0.011147850915169795,0.3188401586074775,0.3076923076923077,0.03594771241830066,0.24183006535947718,0.20588235294117652
TEX55,ENSG00000163424,52.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,52.2,3,0.1,47,52.2,0.0,0.0,0.1,8,0.1,39,522.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,20,LUAD:validation|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
TSACC,ENSG00000163467,899.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,899.2,3,2.3,47,899.2,0.2,0.5,2.3,8,2.2,39,390.9565217391305,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.045180309886192246,0.045180309886192246,0.0,0.053750736443044136,0.36144304413535183,0.3076923076923077,0.21451464707373516,0.42039700001491165,0.20588235294117652
NEK10,ENSG00000163491,34.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,34.3,3,14.1,47,34.3,0.5,0.1,10.1,8,14.1,39,2.4326241134751774,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03465523625432249,0.03465523625432249,0.0,0.12711761159163712,0.43480991928394486,0.3076923076923077,0.3147519250827299,0.5206342780239064,0.20588235294117652
SGO2,ENSG00000163535,31.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,31.6,3,14.5,47,31.6,2.7,2.5,1.8,8,14.5,39,2.179310344827586,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,cervical cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.25607092234726897,0.25607092234726897,0.0,0.17487907585687282,0.4825713835491805,0.3076923076923077,0.2581195636823532,0.46400191662352974,0.20588235294117652
SPDYA,ENSG00000163806,32.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,32.0,3,2.3,47,32.0,1.4,0.2,1.7,8,2.3,39,13.913043478260871,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09433806771620916,0.09433806771620916,0.0,0.05012363085072526,0.35781593854303295,0.3076923076923077,0.23066915848952124,0.43655151143069776,0.20588235294117652
KIF15,ENSG00000163808,7.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.1,3,9.0,47,7.1,0.3,0.7,0.4,8,9.0,39,0.7888888888888889,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|glioma|lymphoma|melanoma|ovarian cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.12116553323983664,0.12116553323983664,0.0,0.07646699989587194,0.3841593075881796,0.3076923076923077,0.08818780974571895,0.29407016268689545,0.20588235294117652
DNALI1,ENSG00000163879,52.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,28.6,3,77.1,47,28.6,12.9,1.5,52.7,8,77.1,39,0.3709468223086901,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.18709771626304017,0.18709771626304017,0.0,0.2487014240260042,0.5563937317183119,0.3076923076923077,0.5436608124868919,0.7495431654280684,0.20588235294117652
CFAP100,ENSG00000163885,31.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,31.5,3,26.2,47,31.5,0.1,0.0,26.2,8,13.0,39,1.202290076335878,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,20,CESC:TCGA|GBM:TCGA|GBM:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.09492605006558669,0.3008084030067632,0.20588235294117652
RPL39L,ENSG00000163923,204.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,204.7,3,19.8,47,204.7,6.4,6.1,12.4,8,19.8,39,10.338383838383837,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,liver cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.4535608294973217,0.4535608294973217,0.0,0.36977051056936544,0.6774628182616731,0.3076923076923077,0.6004794860171335,0.80636183895831,0.20588235294117652
ZDHHC19,ENSG00000163958,48.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,48.7,3,1.5,47,48.7,0.3,0.0,0.0,8,1.5,39,32.46666666666667,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,LIHC:TCGA|LIHC:validation|OV:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.028067154541541114,0.028067154541541114,0.0,0.0,0.3076923076923077,0.3076923076923077,0.046903011736771326,0.2527853646779478,0.20588235294117652
SLC9B1,ENSG00000164037,39.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,39.2,3,2.1,47,39.2,1.1,0.8,2.1,8,1.8,39,18.666666666666668,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,0,BRCA:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|LUAD:validation|LUSC:TCGA|LUSC:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09989963387568737,0.09989963387568737,0.0,0.050916475188307594,0.3586087828806153,0.3076923076923077,0.1817855311141756,0.38766788405535213,0.20588235294117652
CDC25A,ENSG00000164045,12.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,12.9,3,15.1,47,12.9,1.8,2.5,1.0,8,15.1,39,0.8543046357615894,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1761072298826049,0.1761072298826049,0.0,0.1508834791005928,0.4585757867929005,0.3076923076923077,0.23745196777024516,0.44333432071142165,0.20588235294117652
HSPA4L,ENSG00000164070,105.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,105.6,3,26.1,47,105.6,3.7,2.8,7.4,8,26.1,39,4.045977011494252,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.23923979468813644,0.23923979468813644,0.0,0.2642863816146187,0.5719786893069264,0.3076923076923077,0.5274454561121592,0.7333278090533357,0.20588235294117652
CALHM4,ENSG00000164451,22.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,22.5,3,3.9,47,0.3,0.0,22.5,0.1,8,3.9,39,5.769230769230769,False,1,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_CT|daSilva2017_testis_biased,False,False,29,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06003667654112004,0.06003667654112004,0.0,0.003663003663003663,0.31135531135531136,0.3076923076923077,0.025918029114960058,0.23180038205613657,0.20588235294117652
H2AC1,ENSG00000164508,5.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.5,3,0.3,47,5.5,0.0,0.0,0.0,8,0.3,39,18.333333333333336,False,1,0,Cancer-germline,10.1002/cam4.2223|10.18632/oncotarget.21715,Chang2019_TGCT|daSilva2017_testis_biased,False,True,29,20,,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.015821348302166714,0.22170370124334324,0.20588235294117652
ANKRD55,ENSG00000164512,9.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.6,3,3.8,47,9.6,0.1,0.6,0.2,8,3.8,39,2.526315789473684,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BRCA:validation|COAD:validation|GBM:TCGA|GBM:validation|KIRC:validation|LIHC:validation|PAAD:TCGA|TGCT:TCGA,breast cancer|colorectal cancer|lung cancer|ovarian cancer|prostate cancer|skin cancer|stomach cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09422063518342726,0.09422063518342726,0.0,0.05169729840608518,0.3593896060983929,0.3076923076923077,0.14843970829286995,0.35432206123404647,0.20588235294117652
PTTG1,ENSG00000164611,170.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,True,True,True,False,False,True,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal RNA exceeds its applicable local category/IHC ceiling; Normal-cell RNA crosses a source-specific review trigger; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,170.3,3,157.9,47,170.3,11.8,20.5,19.3,8,157.9,39,1.0785307156428119,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer|endometrial cancer|liver cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.699589726606481,0.699589726606481,0.0,0.45804654082565044,0.7657388485179581,0.3076923076923077,0.5519386754629299,0.7578210284041064,0.20588235294117652
IQUB,ENSG00000164675,32.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,32.5,3,4.9,47,32.5,0.3,0.1,4.9,8,2.9,39,6.632653061224489,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Jamin2021_core|Wang2016_CT,True,False,31,0,BRCA:TCGA|BRCA:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|PRAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04892163634968148,0.04892163634968148,0.0,0.023719857753646618,0.3314121654459543,0.3076923076923077,0.1252934488116023,0.33117580175277883,0.20588235294117652
SUN3,ENSG00000164744,40.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,40.4,3,0.1,47,40.4,0.0,0.0,0.1,8,0.1,39,403.99999999999994,False,5,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,CESC:TCGA|HNSC:TCGA|KICH:TCGA|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:validation|PAAD:validation|SKCM:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0007002801120448178,0.20658263305322133,0.20588235294117652
GBX1,ENSG00000164900,5.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.0,3,10.9,47,5.0,0.0,0.0,0.0,8,10.9,39,0.4587155963302752,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT,True,False,31,20,CESC:TCGA|HNSC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.01098901098901099,0.3186813186813187,0.3076923076923077,0.06265878444401016,0.2685411373851867,0.20588235294117652
GKAP1,ENSG00000165113,194.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,194.6,3,48.5,47,194.6,12.5,2.4,8.8,8,48.5,39,4.0123711340206185,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.3696209180470682,0.3696209180470682,0.0,0.37090031347051494,0.6785926211628226,0.3076923076923077,0.638952183268839,0.8448345362100155,0.20588235294117652
SHOC1,ENSG00000165181,21.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,21.3,3,3.7,47,21.3,0.3,0.1,0.3,8,3.7,39,5.756756756756757,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,False,29,0,BLCA:TCGA|CESC:TCGA|COAD:validation|HNSC:TCGA|KICH:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|PAAD:validation|READ:validation|STAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.017589948600799547,0.017589948600799547,0.0,0.01940250705714988,0.32709481474945756,0.3076923076923077,0.09563212844946592,0.3015144813906424,0.20588235294117652
ARMC3,ENSG00000165309,43.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,32.7,3,50.1,47,32.7,0.0,0.0,43.1,8,50.1,39,0.6526946107784432,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,False,31,20,BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.007805440738248582,0.007805440738248582,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.13370618121113628,0.3395885341523128,0.20588235294117652
DEUP1,ENSG00000165325,15.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.9,3,4.6,47,15.9,0.2,0.0,4.6,8,1.4,39,3.456521739130435,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT,True,False,29,0,BRCA:TCGA|CESC:TCGA|COAD:validation|KIRC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02043533009534089,0.02043533009534089,0.0,0.008666461337006022,0.31635876902931376,0.3076923076923077,0.09679012502466693,0.30267247796584346,0.20588235294117652
LRRC18,ENSG00000165383,13.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.2,3,23.9,47,13.2,0.2,0.0,6.4,8,23.9,39,0.5523012552301255,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT,True,False,31,20,BRCA:validation|COAD:validation|GBM:TCGA|GBM:validation|LUAD:TCGA|LUAD:validation|LUSC:validation|OV:TCGA|READ:validation|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.01506431016933469,0.01506431016933469,0.0,0.019401891956096082,0.3270941996484038,0.3076923076923077,0.06560701515944482,0.27148936810062135,0.20588235294117652
SKA3,ENSG00000165480,6.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.1,3,11.8,47,6.1,0.7,1.6,0.7,8,11.8,39,0.5169491525423728,False,2,0,Cancer-germline,10.1038/s41388-018-0357-2|10.18632/oncotarget.21715,Bruggeman2018_GC|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,testis cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.15630258859055968,0.15630258859055968,0.0,0.11101265415817237,0.41870496185048006,0.3076923076923077,0.10991533436589938,0.3157976873070759,0.20588235294117652
DDIAS,ENSG00000165490,10.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.6,3,7.7,47,10.6,0.8,1.8,2.0,8,7.7,39,1.3766233766233766,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.17244269556226838,0.17244269556226838,0.0,0.15195652405437993,0.45964883174668764,0.3076923076923077,0.24503712089778468,0.4509194738389612,0.20588235294117652
RPL10L,ENSG00000165496,89.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,True,False,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,89.4,3,2.6,47,89.4,0.0,0.0,0.0,8,2.6,39,34.38461538461539,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,COAD:TCGA|COAD:validation|LIHC:TCGA|LIHC:validation|LUSC:validation|PAAD:validation|READ:TCGA|READ:validation|TGCT:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Antibody concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.045233835931510355,0.3529261436238181,0.3076923076923077,0.008148714031066972,0.2140310669722435,0.20588235294117652
NOXRED1,ENSG00000165555,6.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.7,3,4.2,47,6.7,0.2,0.2,0.5,8,4.2,39,1.5952380952380951,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,29,20,BRCA:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:validation|KIRP:TCGA|LUAD:validation|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:validation|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,liver cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03813925786451854,0.03813925786451854,0.0,0.025611373534735207,0.3333036812270429,0.3076923076923077,0.1175714558139688,0.3234538087551453,0.20588235294117652
AKR1E2,ENSG00000165568,18.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,18.4,3,3.3,47,18.4,0.9,1.7,2.9,8,3.3,39,5.575757575757575,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|endometrial cancer|renal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1361506852161058,0.1361506852161058,0.0,0.10480361306578306,0.4124959207580908,0.3076923076923077,0.290619089228116,0.49650144216929254,0.20588235294117652
SOHLH1,ENSG00000165643,16.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.4,3,41.6,47,16.4,0.3,0.0,0.1,8,41.6,39,0.39423076923076916,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|HNSC:TCGA|LUSC:TCGA|LUSC:validation|STAD:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013484205563413485,0.013484205563413485,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.09998944620350594,0.30587179914468243,0.20588235294117652
AK8,ENSG00000165695,25.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.5,3,25.0,47,15.5,1.6,0.4,25.0,8,9.9,39,0.62,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,30,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.13175117221776253,0.13175117221776253,0.0,0.0866789809565539,0.3943712886488616,0.3076923076923077,0.21219659511191902,0.41807894805309553,0.20588235294117652
SPACA9,ENSG00000165698,127.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,127.6,3,72.2,47,127.6,10.6,3.1,72.2,8,18.9,39,1.7673130193905815,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.4324233558739344,0.4324233558739344,0.0,0.30627911033695115,0.6139714180292588,0.3076923076923077,0.5736054795237778,0.7794878324649543,0.20588235294117652
PPP1R36,ENSG00000165807,36.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,36.0,3,12.1,47,36.0,0.1,0.8,12.1,8,10.4,39,2.9752066115702482,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|THCA:TCGA|UCEC:TCGA,testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.059937926565765826,0.059937926565765826,0.0,0.17575562852916343,0.48344793622147114,0.3076923076923077,0.26876504895851805,0.47464740189969457,0.20588235294117652
SPMIP5,ENSG00000165863,82.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,82.2,3,1.7,47,82.2,3.6,0.0,0.8,8,1.7,39,48.352941176470594,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Jamin2021_core|Wang2016_CT,True,False,31,0,BRCA:TCGA|BRCA:validation|COAD:TCGA|COAD:validation|LUSC:TCGA|OV:TCGA|OV:validation|PAAD:validation|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0378139658874387,0.0378139658874387,0.0,0.028390957653999984,0.33608326534630767,0.3076923076923077,0.12590386234268752,0.33178621528386404,0.20588235294117652
CCDC38,ENSG00000165972,16.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.3,3,2.7,47,16.3,0.0,0.1,0.2,8,2.7,39,6.037037037037037,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,0,BLCA:TCGA|CESC:TCGA|COAD:validation|KICH:TCGA|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUSC:validation|PAAD:validation|READ:validation|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02290744742423665,0.02290744742423665,0.0,0.007525525769840948,0.31521783346214866,0.3076923076923077,0.10329590846133263,0.30917826140250915,0.20588235294117652
BAG5,ENSG00000166170,124.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,124.1,3,27.4,47,124.1,10.3,13.9,18.1,8,27.4,39,4.529197080291971,False,0,0,,,,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.6567852481308216,0.6567852481308216,0.0,0.49560408621668467,0.8032963939089923,0.3076923076923077,0.6897032880901974,0.895585641031374,0.20588235294117652
TBATA,ENSG00000166220,20.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,20.3,3,125.3,47,20.3,0.0,0.0,0.0,8,125.3,39,0.16201117318435754,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,0,KICH:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1967220415421333,0.1967220415421333,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
DNAAF8,ENSG00000166246,71.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,71.9,3,21.8,47,71.9,1.0,0.2,21.8,8,11.2,39,3.298165137614679,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.07355375719187476,0.07355375719187476,0.0,0.07435476364775334,0.38204707134006105,0.3076923076923077,0.3010224914464871,0.5069048443876636,0.20588235294117652
C11orf65,ENSG00000166323,49.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,49.2,3,2.7,47,49.2,0.5,0.4,2.4,8,2.7,39,18.22222222222222,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:TCGA|BRCA:validation|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.07600637507179564,0.07600637507179564,0.0,0.048217817786638105,0.3559101254789458,0.3076923076923077,0.2061643397716131,0.4120466927127896,0.20588235294117652
BEAN1,ENSG00000166546,1.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.4,3,2.2,47,0.8,0.4,1.4,0.5,8,2.2,39,0.6363636363636362,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,30,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.026818503147537406,0.026818503147537406,0.0,0.023133737034095006,0.3308260447264027,0.3076923076923077,0.08369050294433804,0.28957285588551457,0.20588235294117652
IQCD,ENSG00000166578,43.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,43.0,3,21.4,47,43.0,1.5,0.6,21.3,8,21.4,39,2.0093457943925235,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.07396443680116027,0.07396443680116027,0.0,0.11435718575650727,0.422049493448815,0.3076923076923077,0.3014945226888131,0.5073768756299897,0.20588235294117652
ACSM1,ENSG00000166743,209.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.2,3,209.4,47,4.2,3.2,0.0,209.4,8,9.8,39,0.02005730659025788,False,1,0,Cancer-germline,10.1038/s41388-018-0357-2,Bruggeman2018_GC,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|glioma|liver cancer|prostate cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,False,True,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06776556776556777,0.06776556776556777,0.0,0.086593803945241,0.3942861116375487,0.3076923076923077,0.21854931759294757,0.4244316705341241,0.20588235294117652
C18orf54,ENSG00000166845,16.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.8,3,3.4,47,16.8,1.6,3.0,2.2,8,3.4,39,4.9411764705882355,False,1,0,Cancer-germline,10.1038/s41388-018-0357-2,Bruggeman2018_GC,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.14636138853630956,0.14636138853630956,0.0,0.10710705617403633,0.41479936386634403,0.3076923076923077,0.22271087006798224,0.42859322300915875,0.20588235294117652
PLK1,ENSG00000166851,32.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,32.1,3,42.7,47,32.1,2.2,6.2,3.8,8,42.7,39,0.7517564402810304,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|endometrial cancer|liver cancer|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.36754671286355567,0.36754671286355567,0.0,0.3016840329531205,0.6093763406454282,0.3076923076923077,0.3861513049268127,0.5920336578679892,0.20588235294117652
TAC3,ENSG00000166863,416.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,416.2,3,28.9,47,1.8,2.3,416.2,0.3,8,28.9,39,14.401384083044983,False,0,0,,,,True,False,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUSC:TCGA|OV:TCGA|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02498821310702499,0.02498821310702499,0.0,0.12585609426916547,0.43354840196147315,0.3076923076923077,0.27274704885507023,0.47862940179624675,0.20588235294117652
MS4A14,ENSG00000166928,71.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,71.0,3,11.6,47,71.0,0.7,2.3,3.5,8,11.6,39,6.120689655172414,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,ovarian cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.21196337213247127,0.21196337213247127,0.0,0.11442591768641666,0.42211822537872434,0.3076923076923077,0.3806153927538388,0.5864977456950153,0.20588235294117652
TTC16,ENSG00000167094,15.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.5,3,6.7,47,15.5,0.0,0.0,6.7,8,1.1,39,2.3134328358208953,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1371/journal.pgen.1011734,Chang2019_TGCT|Loriot2025_S2|Wang2016_CT,True,False,31,0,BRCA:TCGA|BRCA:validation|LIHC:validation|LUAD:TCGA|OV:TCGA|OV:validation|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.004807692307692308,0.3125,0.3076923076923077,0.025817381367665995,0.2316997343088425,0.20588235294117652
C16orf92,ENSG00000167194,14.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,14.9,3,34.7,47,14.9,0.0,0.0,0.0,8,34.7,39,0.42939481268011526,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,0,BRCA:TCGA|GBM:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.07948815272878976,0.28537050566996625,0.20588235294117652
LOXHD1,ENSG00000167210,22.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,22.3,3,7.1,47,22.3,0.2,0.7,7.1,8,6.7,39,3.1408450704225355,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|LUAD:validation|PAAD:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06070372386001057,0.06070372386001057,0.0,0.009966236830329904,0.3176585445226376,0.3076923076923077,0.17279304458828088,0.3786753975294574,0.20588235294117652
IGF2,ENSG00000167244,2670.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2670.3,3,382.5,47,23.1,62.1,2670.3,124.2,8,382.5,39,6.9811764705882355,False,0,0,,,,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer|ovarian cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.5461050556158863,0.5461050556158863,0.0,0.4489193573790477,0.7566116650713555,0.3076923076923077,0.6646566698289941,0.8705390227701706,0.20588235294117652
SPATA33,ENSG00000167523,110.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,110.8,3,13.3,47,110.8,3.1,1.7,11.9,8,13.3,39,8.330827067669173,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.3228683762764547,0.3228683762764547,0.0,0.2544998640263703,0.562192171718678,0.3076923076923077,0.5632893518488149,0.7691717047899914,0.20588235294117652
PROCA1,ENSG00000167525,172.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,172.5,3,9.6,47,172.5,5.9,0.6,4.1,8,9.6,39,17.96875,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.21354019373458213,0.21354019373458213,0.0,0.12493094072908595,0.43262324842139366,0.3076923076923077,0.401880503217803,0.6077628561589795,0.20588235294117652
LALBA,ENSG00000167531,2109.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.2,3,2109.2,47,2.2,0.0,0.0,2109.2,8,0.1,39,0.0010430494974397878,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,BRCA:TCGA|BRCA:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
ZNF610,ENSG00000167554,11.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11.7,3,6.5,47,11.7,8.1,2.6,6.5,8,6.0,39,1.7999999999999998,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT|Jamin2021_core,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|glioma|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1801338692329315,0.1801338692329315,0.0,0.14802255958668117,0.4557148672789889,0.3076923076923077,0.37898943246890243,0.5848717854100789,0.20588235294117652
NLRP7,ENSG00000167634,3.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,True,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.8,3,0.6,47,3.8,0.5,0.0,0.0,8,0.6,39,6.333333333333333,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Jamin2021_core|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:validation|OV:TCGA|OV:validation|TGCT:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Antibody concern|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.011320754716981133,0.011320754716981133,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
TTC21A,ENSG00000168026,44.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,44.7,3,7.2,47,44.7,0.7,0.3,7.2,8,1.6,39,6.208333333333334,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|OV:TCGA|OV:validation|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0326092701231436,0.0326092701231436,0.0,0.04470052284210084,0.35239283053440856,0.3076923076923077,0.10750160780807222,0.31338396074924874,0.20588235294117652
PBK,ENSG00000168078,68.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,68.2,3,22.2,47,68.2,2.7,4.9,2.2,8,22.2,39,3.0720720720720722,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.25410080820345615,0.25410080820345615,0.0,0.2430102020423032,0.5507025097346109,0.3076923076923077,0.21207356095154134,0.41795591389271786,0.20588235294117652
H3-4,ENSG00000168148,3.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.0,3,0.2,47,3.0,0.1,0.0,0.2,8,0.2,39,15.0,False,2,0,Cancer-germline,10.1038/ncomms10499|10.1136/jitc-2023-007935,Carter2023_CT|Wang2016_CT,True,True,29,20,COAD:validation|READ:validation,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0037831021437578823,0.3114754098360656,0.3076923076923077,0.003469569646040234,0.20935192258721674,0.20588235294117652
KCNV2,ENSG00000168263,4.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.7,3,280.3,47,4.7,0.2,0.0,0.1,8,280.3,39,0.016767748840528007,False,5,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Jamin2021_CT|Jamin2021_core|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|COAD:validation|READ:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.0342485922008645,0.24013094514204103,0.20588235294117652
TXNDC2,ENSG00000168454,99.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,99.4,3,0.3,47,99.4,0.1,0.0,0.1,8,0.3,39,331.33333333333337,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|GBM:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.025975409926816573,0.2318577628679931,0.20588235294117652
CCDC110,ENSG00000168491,97.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,97.1,3,29.7,47,97.1,3.7,0.8,4.9,8,29.7,39,3.2693602693602695,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.13243297582920224,0.13243297582920224,0.0,0.16532362424807864,0.4730159319403864,0.3076923076923077,0.3167642042209413,0.5226465571621178,0.20588235294117652
DYNLRB2,ENSG00000168589,220.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,220.8,3,58.8,47,220.8,1.3,0.8,58.8,8,56.3,39,3.7551020408163267,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1178460887153461,0.1178460887153461,0.0,0.09078686121253977,0.39847916890484747,0.3076923076923077,0.3456884463401811,0.5515707992813577,0.20588235294117652
KCTD19,ENSG00000168676,32.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,32.0,3,3.3,47,32.0,0.0,0.3,0.8,8,3.3,39,9.696969696969697,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|renal cancer|skin cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.054474829824778616,0.054474829824778616,0.0,0.02779692104123622,0.3354892287335439,0.3076923076923077,0.09845067743608761,0.3043330303772641,0.20588235294117652
ODAD2,ENSG00000169126,39.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,39.5,3,22.4,47,39.5,1.1,0.0,22.4,8,7.8,39,1.7633928571428572,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|PRAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.028794430393516632,0.028794430393516632,0.0,0.03752114490480435,0.34521345259711206,0.3076923076923077,0.17539345697540262,0.38127580991657917,0.20588235294117652
IL13,ENSG00000169194,23.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,Normal,Accepted published protein in non-permitted normal cells,Accepted published protein in non-permitted normal cells; Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,True,False,True,False,legacy-07,https://pubmed.ncbi.nlm.nih.gov/8605923/,legacy-07,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Normal,Accepted published protein in non-permitted normal cells,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,23.6,3,0.5,47,23.6,0.0,0.0,0.1,8,0.5,39,47.2,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:validation|LUAD:validation|LUSC:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Accepted normal protein|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.011613876319758673,0.011613876319758673,0.0,0.004962779156327543,0.31265508684863524,0.3076923076923077,0.012000254647313469,0.21788260758848998,0.20588235294117652
ELSPBP1,ENSG00000169393,2760.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.9,3,2760.0,47,0.9,0.0,0.0,2760.0,8,72.3,39,0.00032608695652173916,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,GBM:TCGA|GBM:validation|KICH:TCGA|KIRP:TCGA|SKCM:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.03743722498175827,0.2433195779229348,0.20588235294117652
RSPH10B2,ENSG00000169402,18.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,18.9,3,9.8,47,18.9,0.1,0.0,9.8,8,3.6,39,1.9285714285714284,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|GBM:validation|LUAD:TCGA|LUAD:validation|OV:TCGA|PAAD:validation|TGCT:TCGA|UCEC:TCGA,liver cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.007805440738248582,0.007805440738248582,0.0,0.015342580916351408,0.32303488860865914,0.3076923076923077,0.07776911993553673,0.2836514728767132,0.20588235294117652
BUB1,ENSG00000169679,29.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,29.4,3,26.8,47,29.4,1.7,3.1,3.4,8,26.8,39,1.0970149253731343,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.27510587433448586,0.27510587433448586,0.0,0.21801617693342726,0.5257084846257349,0.3076923076923077,0.2035831202672068,0.40946547320838333,0.20588235294117652
ACTRT2,ENSG00000169717,151.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,151.0,3,0.1,47,151.0,0.0,0.0,0.1,8,0.0,39,1510.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Wang2016_CT|daSilva2017_testis_biased,False,False,30,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
FAM153A,ENSG00000170074,27.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,27.6,3,4.4,47,27.6,5.3,0.1,4.4,8,4.3,39,6.2727272727272725,False,0,0,,,,True,True,31,20,BRCA:validation|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|THCA:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.13477394600827583,0.13477394600827583,0.0,0.05919710400362629,0.366889411695934,0.3076923076923077,0.21756409480965383,0.42344644775083035,0.20588235294117652
DNAJC18,ENSG00000170464,75.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,75.7,3,15.6,47,75.7,7.2,2.0,6.6,8,15.6,39,4.852564102564103,False,0,0,,,,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.24210334693574379,0.24210334693574379,0.0,0.23723275685392828,0.544925064546236,0.3076923076923077,0.5212813339670663,0.7271636869082428,0.20588235294117652
SPATA24,ENSG00000170469,142.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,142.9,3,22.2,47,142.9,4.2,3.0,20.5,8,22.2,39,6.436936936936937,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2721218952439858,0.2721218952439858,0.0,0.3361658122556999,0.6438581199480076,0.3076923076923077,0.5867373837741705,0.792619736715347,0.20588235294117652
KRT72,ENSG00000170486,23.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,23.0,3,10.2,47,23.0,0.0,0.0,0.1,8,10.2,39,2.2549019607843137,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BRCA:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1505398783438063,0.1505398783438063,0.0,0.026956914053688243,0.33464922174599593,0.3076923076923077,0.09211298731603142,0.2979953402572079,0.20588235294117652
KISS1,ENSG00000170498,226.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,226.4,3,4.4,47,2.5,0.0,226.4,0.3,8,4.4,39,51.45454545454545,False,0,0,Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_placenta_PC|Gong2021_reproductive_PC,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.026541601528573912,0.026541601528573912,0.0,0.0261280917018622,0.3338203993941699,0.3076923076923077,0.13884762502406806,0.34472997796524457,0.20588235294117652
GTSF1,ENSG00000170627,180.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,180.5,3,10.5,47,180.5,1.9,13.6,0.5,8,10.5,39,17.19047619047619,False,5,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,head and neck cancer|lung cancer|lymphoma|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1491070482644031,0.1491070482644031,0.0,0.09098803758846023,0.39868034528076796,0.3076923076923077,0.213408307012254,0.4192906599534305,0.20588235294117652
TTLL6,ENSG00000170703,18.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,18.3,3,4.7,47,18.3,0.0,0.0,3.3,8,4.7,39,3.893617021276596,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BRCA:validation|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005940594059405941,0.005940594059405941,0.0,0.05520022246941046,0.3628925301617182,0.3076923076923077,0.11335393663522839,0.31923628957640493,0.20588235294117652
FSHR,ENSG00000170820,2.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.7,3,0.3,47,2.2,2.7,0.0,0.1,8,0.3,39,9.000000000000002,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,KIRP:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.007672634271099744,0.21355498721227625,0.20588235294117652
MBD3L1,ENSG00000170948,26.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,26.3,3,3.8,47,26.3,0.0,0.0,3.8,8,0.7,39,6.921052631578948,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.015250544662309367,0.2211328976034859,0.20588235294117652
CSN3,ENSG00000171209,350.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.2,3,350.7,47,0.2,0.0,0.0,350.7,8,65.7,39,0.0005702879954376961,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,BRCA:TCGA|BRCA:validation|LUSC:TCGA|LUSC:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.07296738893445602,0.38065969662676374,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
XAGE3,ENSG00000171402,368.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,368.3,3,3.0,47,1.3,0.0,368.3,0.6,8,3.0,39,122.76666666666667,False,1,0,Cancer-germline|Cancer-placental|Cancer-reproductive,10.1038/ncomms10499|10.1038/s41467-021-22695-y,Gong2021_placenta_PC|Gong2021_reproductive_PC|Wang2016_CT,True,True,31,20,LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|OV:TCGA|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.046153846153846156,0.046153846153846156,0.0,0.003663003663003663,0.31135531135531136,0.3076923076923077,0.057277760602568784,0.2631601135437453,0.20588235294117652
NLRP5,ENSG00000171487,6.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.4,3,21.7,47,0.2,6.4,0.0,0.1,8,21.7,39,0.29493087557603687,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:TCGA|BRCA:validation,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|liver cancer|lung cancer|melanoma|pancreatic cancer|prostate cancer|stomach cancer|testis cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.06026103860038878,0.3679533462926965,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
OTP,ENSG00000171540,0.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.2,3,12.9,47,0.2,0.0,0.0,0.0,8,12.9,39,0.015503875968992248,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,GBM:TCGA|GBM:validation,renal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.013305108498555004,0.21918746143973153,0.20588235294117652
LKAAEAR1,ENSG00000171695,31.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,31.4,3,5.8,47,31.4,0.0,0.0,2.5,8,5.8,39,5.413793103448276,False,0,0,,,,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|GBM:TCGA|GBM:validation|LUSC:TCGA|OV:TCGA|OV:validation|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009862162686856923,0.009862162686856923,0.0,0.0,0.3076923076923077,0.3076923076923077,0.10524433293528675,0.31112668587646325,0.20588235294117652
SPATA46,ENSG00000171722,30.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,30.1,3,3.1,47,30.1,0.0,0.0,0.1,8,3.1,39,9.709677419354838,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,0,BRCA:TCGA|COAD:validation|LUAD:validation|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.008666461337006022,0.31635876902931376,0.3076923076923077,0.09286770093293231,0.2987500538741088,0.20588235294117652
SYCE1,ENSG00000171772,68.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,68.9,3,17.5,47,68.9,1.9,9.0,1.6,8,17.5,39,3.9371428571428573,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.08347646375294372,0.08347646375294372,0.0,0.054852015884203895,0.3625443235765116,0.3076923076923077,0.30944766533502377,0.5153300182762003,0.20588235294117652
UTF1,ENSG00000171794,5.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.8,3,0.2,47,5.8,0.5,0.0,0.2,8,0.1,39,28.999999999999996,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|TGCT:TCGA,testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0035014005602240893,0.2093837535014006,0.20588235294117652
PRND,ENSG00000171864,68.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,68.8,3,39.4,47,68.8,0.5,0.1,4.0,8,39.4,39,1.7461928934010151,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:validation|OV:TCGA|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009862162686856923,0.009862162686856923,0.0,0.03323567454753486,0.34092798223984255,0.3076923076923077,0.044208065307809546,0.25009041824898604,0.20588235294117652
SLC9C1,ENSG00000172139,7.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.8,3,2.1,47,7.8,0.0,0.0,0.0,8,2.1,39,3.714285714285714,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,0,COAD:validation|GBM:validation|PAAD:validation|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03863231242910387,0.03863231242910387,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.010473754719279015,0.21635610766045554,0.20588235294117652
C5orf34,ENSG00000172244,4.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.0,3,3.5,47,4.0,1.0,1.0,2.3,8,3.5,39,1.1428571428571428,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|liver cancer|lung cancer|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1277080441649736,0.1277080441649736,0.0,0.10186536338106077,0.4095576710733685,0.3076923076923077,0.17278247695189367,0.37866482989307015,0.20588235294117652
CFAP53,ENSG00000172361,77.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,77.4,3,27.6,47,77.4,0.8,0.3,27.6,8,19.9,39,2.8043478260869565,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.095237776656528,0.095237776656528,0.0,0.06248228611752186,0.3701745938098296,0.3076923076923077,0.3207490046632818,0.5266313576044583,0.20588235294117652
ZFAND4,ENSG00000172671,36.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,36.3,3,6.6,47,36.3,2.4,1.2,2.9,8,6.6,39,5.5,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,False,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.21899129250164717,0.21899129250164717,0.0,0.17782618320289895,0.48551849089520666,0.3076923076923077,0.4391010294541976,0.6449833823953741,0.20588235294117652
TMEM217,ENSG00000172738,8.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.7,3,2.9,47,8.7,0.4,0.3,1.5,8,2.9,39,3.0,False,5,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Jamin2021_core|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.05792430911138744,0.05792430911138744,0.0,0.07235459443546677,0.3800469021277745,0.3076923076923077,0.19756627103672336,0.4034486239778999,0.20588235294117652
CFAP184,ENSG00000173013,63.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,63.6,3,12.5,47,63.6,0.7,0.5,10.3,8,12.5,39,5.088,False,0,0,,,,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,renal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09633497434776334,0.09633497434776334,0.0,0.08380632905714466,0.3914986367494524,0.3076923076923077,0.31227170838260304,0.5181540613237796,0.20588235294117652
CCDC63,ENSG00000173093,16.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.8,3,2.6,47,16.8,0.0,0.0,0.0,8,2.6,39,6.461538461538462,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,0,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.05845816587504567,0.26434051881622217,0.20588235294117652
ADAMTS20,ENSG00000173157,0.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,True,False,True,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.5,3,0.6,47,0.3,0.0,0.5,0.0,8,0.6,39,0.8333333333333334,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:validation|GBM:validation|HNSC:TCGA|LUAD:TCGA|LUSC:TCGA|LUSC:validation|SKCM:TCGA|TGCT:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Antibody concern|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.007137470372764489,0.213019823313941,0.20588235294117652
TUBB8B,ENSG00000173213,1.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.5,3,0.0,38,0.6,1.5,0.0,0.0,7,0.0,31,,True,2,0,Cancer-germline,10.1002/cam4.2223|10.1371/journal.pgen.1011734,Chang2019_TGCT|Loriot2025_S2,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|HNSC:TCGA|KICH:TCGA|KIRP:TCGA|LUAD:TCGA|LUSC:TCGA|OV:TCGA|OV:validation|PAAD:validation|PRAD:TCGA|SKCM:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,glioma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.36764705882352944,0.36764705882352944
PLAC8L1,ENSG00000173261,17.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,17.9,3,2.4,47,17.9,0.4,0.0,0.7,8,2.4,39,7.458333333333333,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:validation|COAD:validation|GBM:TCGA|GBM:validation|LIHC:validation|OV:validation|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03983637276918062,0.03983637276918062,0.0,0.020879580933785058,0.32857188862609277,0.3076923076923077,0.16050363142233479,0.36638598436351133,0.20588235294117652
SLC2A14,ENSG00000173262,79.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,79.4,3,6.4,47,79.4,2.7,1.1,1.2,8,6.4,39,12.40625,False,2,0,Cancer-germline|Cancer-reproductive,10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734,Bruggeman2018_GC|Gong2021_reproductive_PC|Loriot2025_S2,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,ovarian cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.05899166936443456,0.05899166936443456,0.0,0.051983814342390175,0.3596761220346979,0.3076923076923077,0.2753932462638586,0.4812755992050351,0.20588235294117652
CIMIP2C,ENSG00000173557,25.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,25.8,3,8.5,47,25.8,0.0,0.0,7.3,8,8.5,39,3.0352941176470587,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,melanoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02378021585942379,0.02378021585942379,0.0,0.06620496687845077,0.3738972745707585,0.3076923076923077,0.11207380941366547,0.317956162354842,0.20588235294117652
APOBEC4,ENSG00000173627,11.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.7,3,11.2,47,9.7,0.0,0.0,11.2,8,1.1,39,0.8660714285714286,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:validation|COAD:validation|LUAD:TCGA|LUAD:validation|LUSC:validation|OV:TCGA|OV:validation|READ:validation|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,False,True,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.025955932984984876,0.2318382859261614,0.20588235294117652
TAS1R1,ENSG00000173662,4.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.2,3,0.7,47,4.2,0.4,0.1,0.2,8,0.7,39,6.000000000000001,False,0,0,,,,True,True,31,20,BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|HNSC:TCGA|LUAD:TCGA|LUAD:validation|OV:TCGA|OV:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.022824762260592636,0.022824762260592636,0.0,0.021590312987800696,0.3292826206801084,0.3076923076923077,0.05460609296926432,0.26048844591044085,0.20588235294117652
MARCHF10,ENSG00000173838,133.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,133.7,3,17.8,47,133.7,0.1,0.0,12.4,8,17.8,39,7.511235955056179,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|SKCM:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,glioma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.011803533294505923,0.011803533294505923,0.0,0.02446316463370932,0.33215547232601705,0.3076923076923077,0.17628688828542755,0.38216924122660406,0.20588235294117652
PHOSPHO1,ENSG00000173868,100.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,100.1,3,18.7,47,100.1,0.2,6.2,1.3,8,18.7,39,5.352941176470588,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.19659426839947813,0.19659426839947813,0.0,0.0950281562775786,0.4027204639698863,0.3076923076923077,0.3500148527874391,0.5558972057286156,0.20588235294117652
CBX2,ENSG00000173894,12.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,12.5,3,7.2,47,12.5,2.3,2.1,1.7,8,7.2,39,1.7361111111111112,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,cervical cancer|endometrial cancer|glioma|melanoma|pancreatic cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.17872568349502466,0.17872568349502466,0.0,0.0961585769248155,0.4038508846171232,0.3076923076923077,0.22201301114344593,0.4278953640846225,0.20588235294117652
KRT28,ENSG00000173908,0.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.2,3,11.3,47,0.2,0.0,0.0,0.7,8,11.3,39,0.017699115044247787,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.11192852910342313,0.11192852910342313,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
SPATA31G1,ENSG00000174038,34.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,34.8,3,2.6,47,34.8,0.1,0.5,2.6,8,2.6,39,13.384615384615383,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.05023318223141064,0.05023318223141064,0.0,0.04113395225908533,0.34882625995139305,0.3076923076923077,0.136879606527568,0.34276195946874455,0.20588235294117652
PCP2,ENSG00000174788,109.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,109.3,3,116.2,47,109.3,0.1,0.3,5.7,8,116.2,39,0.9406196213425129,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2488604520702351,0.2488604520702351,0.0,0.15736667201218144,0.4650589797044892,0.3076923076923077,0.3982258037783044,0.6041081567194809,0.20588235294117652
ODAPH,ENSG00000174792,5.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.7,3,1.0,47,0.4,0.1,5.7,0.1,8,1.0,39,5.7,False,0,0,,,,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|PAAD:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.00788196466705494,0.00788196466705494,0.0,0.007525525769840948,0.31521783346214866,0.3076923076923077,0.08250832713748316,0.28839068007865964,0.20588235294117652
CATSPERD,ENSG00000174898,8.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.4,3,0.0,47,8.4,0.0,0.0,0.0,8,0.0,39,,True,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,20,GBM:validation|OV:validation|PAAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CATSPER1,ENSG00000175294,16.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.8,3,0.5,47,16.8,0.0,0.0,0.0,8,0.5,39,33.6,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:validation|GBM:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|OV:validation|PAAD:TCGA|PAAD:validation|SKCM:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.007805440738248582,0.007805440738248582,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.027521008403361344,0.23340336134453787,0.20588235294117652
RFESD,ENSG00000175449,11.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11.9,3,17.6,47,11.9,2.2,0.9,3.9,8,17.6,39,0.6761363636363636,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2046622558511326,0.2046622558511326,0.0,0.17760927648778904,0.4853015841800967,0.3076923076923077,0.4305116576623975,0.636394010603574,0.20588235294117652
PRM1,ENSG00000175646,13722.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13722.9,3,12.4,47,13722.9,1.6,0.0,12.4,8,5.6,39,1106.6854838709676,False,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,True,True,31,20,TGCT:TCGA,colorectal cancer|skin cancer,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.17117052937606697,0.17117052937606697,0.0,0.09763876554138869,0.4053310732336964,0.3076923076923077,0.32788090699931527,0.5337632599404918,0.20588235294117652
TEX26,ENSG00000175664,20.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,20.9,3,11.6,47,20.9,0.0,0.0,0.8,8,11.6,39,1.8017241379310345,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,0,GBM:TCGA|GBM:validation|LUAD:TCGA|LUAD:validation|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.07821273406280392,0.28409508700398045,0.20588235294117652
ZNF683,ENSG00000176083,79.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,79.6,3,9.8,47,79.6,0.5,0.4,1.6,8,9.8,39,8.122448979591836,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.10825643830322974,0.10825643830322974,0.0,0.12048831412421254,0.4281806218165203,0.3076923076923077,0.18817562327792506,0.39405797621910155,0.20588235294117652
HMGB4,ENSG00000176256,361.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,361.1,3,0.1,47,361.1,0.0,0.0,0.0,8,0.1,39,3611.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
CNTD1,ENSG00000176563,41.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,41.1,3,3.2,47,41.1,0.3,0.1,1.8,8,3.2,39,12.84375,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.015610881476497165,0.015610881476497165,0.0,0.06687969294080665,0.37457200063311435,0.3076923076923077,0.10607609324402492,0.3119584461852014,0.20588235294117652
CNBD1,ENSG00000176571,4.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,True,False,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Uncertain normal antibody evidence requires review; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.9,3,0.3,47,4.9,0.0,0.0,0.0,8,0.3,39,16.333333333333336,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_testis_biased,True,True,31,20,GBM:validation,prostate cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Antibody concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005825242718446602,0.005825242718446602,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.0014005602240896356,0.20728291316526615,0.20588235294117652
PFN4,ENSG00000176732,78.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,78.8,3,2.9,47,78.8,1.3,0.5,1.9,8,2.9,39,27.17241379310345,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.07884476248288005,0.07884476248288005,0.0,0.06018123892271256,0.36787354661502025,0.3076923076923077,0.1950682099037577,0.40095056284493424,0.20588235294117652
EFCAB5,ENSG00000176927,8.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.3,3,1.2,47,8.3,0.0,0.1,0.1,8,1.2,39,6.916666666666668,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:validation|COAD:TCGA|COAD:validation|GBM:validation|LIHC:validation|LUAD:validation|PAAD:validation|READ:validation|SKCM:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.011803533294505923,0.011803533294505923,0.0,0.029517549494415235,0.3372098571867229,0.3076923076923077,0.0669314168355089,0.2728137697766854,0.20588235294117652
FAM9B,ENSG00000177138,5.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.7,3,3.0,47,5.7,0.2,0.0,1.5,8,3.0,39,1.9000000000000001,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,CESC:TCGA|COAD:validation|KIRC:validation|LIHC:TCGA|LIHC:validation|PAAD:validation|PRAD:TCGA|TGCT:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.011652703731911653,0.011652703731911653,0.0,0.0037424236260830655,0.3114347313183908,0.3076923076923077,0.0829477640858715,0.28883011702704803,0.20588235294117652
BEND2,ENSG00000177324,5.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.2,3,0.2,47,5.2,0.0,0.0,0.0,8,0.2,39,26.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|CESC:TCGA|KICH:TCGA|KIRP:TCGA|PAAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0053475935828877,0.2112299465240642,0.20588235294117652
VCX2,ENSG00000177504,27.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,27.2,3,0.0,47,27.2,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S1|Wang2016_CT|daSilva2017_testis_biased,True,False,31,20,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
C12orf54,ENSG00000177627,38.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,38.8,3,0.6,47,38.8,0.4,0.1,0.3,8,0.6,39,64.66666666666667,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:validation|CESC:TCGA|GBM:validation|HNSC:TCGA|LUSC:TCGA|LUSC:validation|PAAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0039603960396039604,0.0039603960396039604,0.0,0.011072184029613963,0.3187644917219217,0.3076923076923077,0.02355764440163417,0.22943999734281068,0.20588235294117652
CIMIP6,ENSG00000177994,49.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,49.2,3,7.3,47,49.2,0.3,0.0,7.3,8,3.8,39,6.739726027397261,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BRCA:TCGA|BRCA:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:validation|OV:TCGA|OV:validation|THCA:TCGA|UCEC:TCGA,breast cancer|lymphoma|melanoma|ovarian cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02378021585942379,0.02378021585942379,0.0,0.011571841851494697,0.3192641495438024,0.3076923076923077,0.1299786018942805,0.335860954835457,0.20588235294117652
MLF1,ENSG00000178053,382.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,382.7,3,175.9,47,382.7,12.4,2.6,65.7,8,175.9,39,2.175667993177942,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,endometrial cancer|lung cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.38866059010762327,0.38866059010762327,0.0,0.410910021588449,0.7186023292807567,0.3076923076923077,0.6652693555693673,0.8711517085105438,0.20588235294117652
PPP1R42,ENSG00000178125,8.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,True,False,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.9,3,5.3,47,8.9,0.0,0.0,5.3,8,1.1,39,1.679245283018868,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,29,20,GBM:TCGA|GBM:validation|OV:TCGA|OV:validation|UCEC:TCGA,liver cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Antibody concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005825242718446602,0.005825242718446602,0.0,0.003663003663003663,0.31135531135531136,0.3076923076923077,0.040328475322493965,0.24621082826367047,0.20588235294117652
LCORL,ENSG00000178177,5.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.7,3,6.8,47,5.7,3.9,3.8,2.9,8,6.8,39,0.8382352941176471,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,liver cancer|pancreatic cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2615832786203727,0.2615832786203727,0.0,0.23893760819119114,0.5466299158834989,0.3076923076923077,0.47529132220749193,0.6811736751486684,0.20588235294117652
PRM3,ENSG00000178257,86.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,86.4,3,2.6,47,86.4,0.0,0.0,0.1,8,2.6,39,33.23076923076923,False,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,31,0,COAD:validation|LUAD:validation|LUSC:validation|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.015242323344432113,0.015242323344432113,0.0,0.0074054272890867285,0.31509773498139443,0.3076923076923077,0.05333338869144496,0.25921574163262145,0.20588235294117652
NEUROG2,ENSG00000178403,1.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.6,3,2.1,47,1.6,0.0,0.0,0.1,8,2.1,39,0.7619047619047619,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|READ:TCGA|READ:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.024680275487305614,0.23056262842848213,0.20588235294117652
MCMDC2,ENSG00000178460,11.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11.6,3,5.8,47,11.6,1.3,0.5,1.2,8,5.8,39,2.0,False,4,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.10280410554826541,0.10280410554826541,0.0,0.11523436289603377,0.4229266705883415,0.3076923076923077,0.3196908811489917,0.5255732340901682,0.20588235294117652
KLHL11,ENSG00000178502,9.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.4,3,8.9,47,9.4,3.1,2.0,3.9,8,8.9,39,1.0561797752808988,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT|Jamin2021_core,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,cervical cancer|colorectal cancer|liver cancer|melanoma|ovarian cancer|renal cancer|testis cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.22584080782674282,0.22584080782674282,0.0,0.1838983160426151,0.4915906237349228,0.3076923076923077,0.40747172001413806,0.6133540729553146,0.20588235294117652
H1-8,ENSG00000178804,7.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.1,3,0.0,47,7.1,0.2,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,29,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
C9orf50,ENSG00000179058,8.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.3,3,1.7,47,8.3,0.1,0.0,0.4,8,1.7,39,4.882352941176471,False,0,0,,,,True,True,31,20,BRCA:validation|COAD:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|OV:TCGA|OV:validation|READ:validation|SKCM:TCGA|THCA:TCGA|UCEC:TCGA,glioma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.007920792079207921,0.007920792079207921,0.0,0.009848075421845914,0.3175403831141536,0.3076923076923077,0.08839091410751622,0.2942732670486927,0.20588235294117652
CCDC89,ENSG00000179071,42.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,42.4,3,7.6,47,42.4,4.2,0.6,7.6,8,1.6,39,5.578947368421053,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03831924642135519,0.03831924642135519,0.0,0.0624197475904129,0.3701120552827206,0.3076923076923077,0.19969196385013618,0.40557431679131273,0.20588235294117652
FAM133A,ENSG00000179083,7.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.5,3,4.7,47,7.5,0.6,0.0,0.5,8,4.7,39,1.5957446808510638,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005901766647252961,0.005901766647252961,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.15138237758784667,0.3572647305290232,0.20588235294117652
C12orf42,ENSG00000179088,16.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.7,3,1.3,47,16.7,0.0,0.0,0.0,8,1.3,39,12.846153846153845,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT,True,False,31,0,BRCA:validation|GBM:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04119066773934031,0.04119066773934031,0.0,0.00904977375565611,0.31674208144796384,0.3076923076923077,0.012955182072829132,0.21883753501400566,0.20588235294117652
C10orf67,ENSG00000179133,12.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,12.0,3,5.5,47,12.0,0.3,0.1,4.7,8,5.5,39,2.1818181818181817,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.034873949579831934,0.034873949579831934,0.0,0.014775866210292442,0.32246817390260013,0.3076923076923077,0.18354849422624359,0.3894308471674201,0.20588235294117652
GGN,ENSG00000179168,93.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,93.6,3,2.8,47,93.6,0.3,0.0,0.8,8,2.8,39,33.42857142857143,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUSC:TCGA|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.042440075372883225,0.042440075372883225,0.0,0.027496446339729922,0.33518875403203763,0.3076923076923077,0.16697601595802497,0.3728583688992015,0.20588235294117652
TMEM31,ENSG00000179363,107.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,107.0,3,2.2,47,107.0,1.7,0.8,1.3,8,2.2,39,48.63636363636363,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Jamin2021_core|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|OV:TCGA|OV:validation|PRAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03472740851381628,0.03472740851381628,0.0,0.02972984024540424,0.33742214793771197,0.3076923076923077,0.14828676865535273,0.35416912159652925,0.20588235294117652
CATSPERE,ENSG00000179397,20.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,20.9,3,2.6,47,20.9,0.7,0.5,2.6,8,1.0,39,8.038461538461538,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,0,BRCA:TCGA|GBM:validation|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:validation|OV:validation|PAAD:validation|SKCM:TCGA|TGCT:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04721186595240216,0.04721186595240216,0.0,0.038170880110013086,0.3458631878023208,0.3076923076923077,0.16421530653385313,0.37009765947502965,0.20588235294117652
TPPP2,ENSG00000179636,247.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,247.7,3,12.8,47,247.7,0.5,0.0,3.4,8,12.8,39,19.351562499999996,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|GBM:validation|KICH:TCGA|LIHC:TCGA|LIHC:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.007920792079207921,0.007920792079207921,0.0,0.05744754290497284,0.36513985059728055,0.3076923076923077,0.15727555125225623,0.36315790419343275,0.20588235294117652
WFDC11,ENSG00000180083,91.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.9,3,91.7,47,4.9,0.1,0.2,91.7,8,2.9,39,0.05343511450381679,False,2,0,Cancer-germline|Cancer-reproductive,10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,0,BRCA:TCGA|COAD:validation|KIRC:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03393009377664109,0.03393009377664109,0.0,0.020581568968665743,0.32827387666097346,0.3076923076923077,0.09354685930316183,0.2994292122443383,0.20588235294117652
TDRD6,ENSG00000180113,29.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,29.5,3,10.6,47,29.5,1.1,1.5,3.3,8,10.6,39,2.7830188679245285,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Jamin2021_core|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.17350780016108783,0.17350780016108783,0.0,0.09268284200128972,0.40037514969359744,0.3076923076923077,0.32750507027708375,0.5333874232182603,0.20588235294117652
C11orf71,ENSG00000180425,135.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,135.1,3,22.1,47,135.1,7.1,3.5,22.1,8,21.6,39,6.113122171945701,False,2,0,Cancer-germline,10.1038/s41388-018-0357-2|10.18632/oncotarget.21715,Bruggeman2018_GC|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.4649211788109232,0.4649211788109232,0.0,0.3719282771289497,0.6796205848212574,0.3076923076923077,0.6404134485517587,0.8462958014929353,0.20588235294117652
GLIPR1L2,ENSG00000180481,45.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,45.3,3,6.4,47,45.3,5.4,0.8,3.5,8,6.4,39,7.078124999999999,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1305941484274427,0.1305941484274427,0.0,0.10555790737490933,0.41325021506721704,0.3076923076923077,0.3723665618296399,0.5782489147708164,0.20588235294117652
DEFB119,ENSG00000180483,1870.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,322.3,3,1870.7,47,322.3,0.0,0.0,1870.7,8,150.8,39,0.17228844817448014,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,GBM:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005940594059405941,0.005940594059405941,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.044474581470269794,0.2503569344114463,0.20588235294117652
ANKRD30B,ENSG00000180777,8.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,True,False,True,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.6,3,1.4,47,8.6,0.0,0.0,1.4,8,0.6,39,6.142857142857143,False,0,0,,,,True,True,31,20,BRCA:TCGA|BRCA:validation|COAD:validation|GBM:validation|PAAD:validation|READ:validation|SKCM:TCGA|TGCT:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,High normal RNA|Antibody concern|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.007805440738248582,0.007805440738248582,0.0,0.0037424236260830655,0.3114347313183908,0.3076923076923077,0.02558299543593661,0.23146534837711313,0.20588235294117652
PENK,ENSG00000181195,125.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,125.4,3,738.6,47,125.4,28.8,2.8,22.6,8,738.6,39,0.16978066612510154,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1279407254436189,0.1279407254436189,0.0,0.20877669416960612,0.5164690018619138,0.3076923076923077,0.4574910147310608,0.6633733676722373,0.20588235294117652
EDDM3A,ENSG00000181562,620.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.1,3,620.9,47,1.1,0.0,0.0,620.9,8,0.7,39,0.0017716218392655825,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BRCA:validation|KICH:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.01591899386017033,0.22180134680134683,0.20588235294117652
MEX3D,ENSG00000181588,76.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,76.1,3,12.2,47,76.1,11.9,6.5,12.2,8,11.5,39,6.237704918032787,False,0,0,,,,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.3317995750078744,0.3317995750078744,0.0,0.2895979366984861,0.5972902443907938,0.3076923076923077,0.5134290618830386,0.7193114148242151,0.20588235294117652
CIMAP1D,ENSG00000181781,22.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,22.8,3,8.0,47,22.8,0.0,0.2,0.3,8,8.0,39,2.85,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,True,31,20,BRCA:validation|PRAD:TCGA|READ:TCGA|SKCM:TCGA|UCEC:TCGA,colorectal cancer|head and neck cancer|lung cancer|lymphoma|melanoma|skin cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.026714795606227894,0.026714795606227894,0.0,0.006264491721921653,0.3139567994142294,0.3076923076923077,0.11858794681684706,0.32447029975802355,0.20588235294117652
KPNA2,ENSG00000182481,203.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,203.2,3,102.0,47,203.2,11.2,42.4,25.1,8,102.0,39,1.9921568627450978,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.7074541622318735,0.7074541622318735,0.0,0.5513089198799708,0.8590012275722785,0.3076923076923077,0.7158975964933023,0.9217799494344788,0.20588235294117652
PAPPA,ENSG00000182752,70.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,Normal,Accepted published protein in non-permitted normal cells,Accepted published protein in non-permitted normal cells; Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,True,False,True,False,legacy-08,https://pubmed.ncbi.nlm.nih.gov/17936662/,legacy-08,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Normal,Accepted published protein in non-permitted normal cells,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,70.0,3,8.8,47,0.8,1.4,70.0,4.0,8,8.8,39,7.954545454545454,False,1,0,Cancer-germline|Cancer-placental|Cancer-reproductive,10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y,Bruggeman2018_GC|Gong2021_placenta_PC|Gong2021_reproductive_PC,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Accepted normal protein|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.11145074509663858,0.11145074509663858,0.0,0.1764871907084713,0.484179498400779,0.3076923076923077,0.24031671263820875,0.44619906557938527,0.20588235294117652
TMEM95,ENSG00000182896,10.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.8,3,0.0,47,10.8,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_testis_biased,False,False,31,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CIMAP1C,ENSG00000182950,21.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,21.9,3,2.9,47,21.9,0.2,0.2,1.2,8,2.9,39,7.551724137931034,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09532863351280066,0.09532863351280066,0.0,0.060078857547802095,0.3677711652401098,0.3076923076923077,0.16177821292144723,0.36766056586262374,0.20588235294117652
C12orf60,ENSG00000182993,14.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,14.3,3,6.2,47,14.3,0.5,0.6,1.3,8,6.2,39,2.306451612903226,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.10708493269902583,0.10708493269902583,0.0,0.07715869704828344,0.38485100474059114,0.3076923076923077,0.3236977571496524,0.5295801100908288,0.20588235294117652
WBP2NL,ENSG00000183066,17.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,17.3,3,1.2,47,17.3,0.6,0.1,1.2,8,0.7,39,14.416666666666668,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BRCA:validation|GBM:validation|KICH:TCGA|KIRC:validation|OV:TCGA|OV:validation|PAAD:validation|SKCM:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02883639768399277,0.02883639768399277,0.0,0.0243947710820143,0.33208707877432203,0.3076923076923077,0.08538243749241191,0.29126479043358844,0.20588235294117652
ABHD16B,ENSG00000183260,15.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.5,3,3.5,47,15.5,0.4,0.5,1.2,8,3.5,39,4.428571428571429,False,0,0,,,,True,True,30,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,carcinoid|lung cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1126973126973127,0.1126973126973127,0.0,0.06812403116557926,0.37581633885788696,0.3076923076923077,0.20437870147427356,0.4102610544154501,0.20588235294117652
REC114,ENSG00000183324,38.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,38.1,3,4.5,47,38.1,2.5,0.0,0.0,8,4.5,39,8.466666666666667,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,0,COAD:validation|READ:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.04339777869189634,0.24928013163307286,0.20588235294117652
SH2D7,ENSG00000183476,3.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.0,3,2.3,47,3.0,0.0,0.1,0.1,8,2.3,39,1.3043478260869565,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,COAD:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|STAD:TCGA|UCEC:TCGA,pancreatic cancer|skin cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.02320683018726382,0.33089913787957154,0.3076923076923077,0.04879329514206348,0.25467564808324,0.20588235294117652
MARCHF11,ENSG00000183654,80.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,80.1,3,9.7,47,80.1,0.3,0.0,0.3,8,9.7,39,8.257731958762887,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,0,BRCA:TCGA|GBM:TCGA|GBM:validation|KICH:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PRAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.012250045036930285,0.319942352729238,0.3076923076923077,0.21017657310188204,0.41605892604305855,0.20588235294117652
ANKRD45,ENSG00000183831,12.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.7,3,12.3,47,10.7,1.2,0.0,12.3,8,9.0,39,0.8699186991869917,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.025059254471019178,0.025059254471019178,0.0,0.05115730382784851,0.3588496115201562,0.3076923076923077,0.19562671321819208,0.4015090661593686,0.20588235294117652
MROH7,ENSG00000184313,53.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,53.9,3,9.8,47,53.9,2.8,0.0,2.2,8,9.8,39,5.499999999999999,False,0,0,,,,True,False,29,20,GBM:validation|KICH:TCGA|KIRC:TCGA|KIRP:TCGA|LIHC:TCGA|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09190656759696406,0.09190656759696406,0.0,0.0942684627268486,0.40196077041915634,0.3076923076923077,0.2619605198773495,0.467842872818526,0.20588235294117652
ACTRT3,ENSG00000184378,46.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,46.1,3,2.7,47,46.1,1.7,1.0,2.0,8,2.7,39,17.074074074074073,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,liver cancer|lung cancer|skin cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.08084779022994126,0.08084779022994126,0.0,0.09407121992307577,0.4017635276153835,0.3076923076923077,0.2752059587795206,0.4810883117206971,0.20588235294117652
CDCA2,ENSG00000184661,18.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,18.9,3,11.1,47,18.9,0.4,1.2,0.6,8,11.1,39,1.7027027027027026,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,cervical cancer|colorectal cancer|head and neck cancer|lung cancer|melanoma|stomach cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1457496714240677,0.1457496714240677,0.0,0.10507955074381899,0.4127718584361267,0.3076923076923077,0.10486414245331999,0.3107464953944965,0.20588235294117652
CLDN6,ENSG00000184697,0.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,True,False,False,False,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.9,3,1.0,47,0.9,0.0,0.7,0.1,8,1.0,39,0.9,False,0,0,,,,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|HNSC:TCGA|KICH:TCGA|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,Oncofetal,Membership support,Reviewed reproductive/developmental and tumor association supports biological membership; not a safety or approval claim.,https://pubmed.ncbi.nlm.nih.gov/41073135/,Rare normal pediatric positive cells are reported; adult and pediatric populations require separate interpretation.,Locus,True,True,False,False,False,False,Established,Oncofetal,Reviewed reproductive/developmental and tumor association,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.07186022153170932,0.27774257447288586,0.20588235294117652
DYNLT2,ENSG00000184786,17.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,17.7,3,0.1,47,17.7,0.0,0.0,0.0,8,0.1,39,176.99999999999997,False,4,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,0,GBM:validation|PAAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0028011204481792713,0.20868347338935578,0.20588235294117652
MFSD6L,ENSG00000185156,24.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,24.8,3,9.1,47,24.8,0.0,0.4,2.0,8,9.1,39,2.7252747252747254,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,carcinoid|cervical cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|skin cancer|stomach cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06329244012372451,0.06329244012372451,0.0,0.16424815494582937,0.47194046263813705,0.3076923076923077,0.15421320497760546,0.360095557918782,0.20588235294117652
NOTUM,ENSG00000185269,131.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,131.0,3,9.7,47,2.7,0.0,131.0,2.0,8,9.7,39,13.50515463917526,False,1,0,Cancer-germline,10.1038/s41388-018-0357-2,Bruggeman2018_GC,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03863231242910387,0.03863231242910387,0.0,0.05940672795876416,0.3670990356510719,0.3076923076923077,0.205059751868667,0.4109421048098435,0.20588235294117652
NUPR2,ENSG00000185290,345.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,345.0,3,17.7,47,345.0,1.4,0.6,6.3,8,17.7,39,19.491525423728813,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.21536510901747966,0.21536510901747966,0.0,0.1584425534347346,0.4661348611270423,0.3076923076923077,0.3965810079988091,0.6024633609399856,0.20588235294117652
SPATA45,ENSG00000185523,11.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11.5,3,2.9,47,11.5,0.1,0.3,0.7,8,2.9,39,3.9655172413793105,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,29,20,GBM:TCGA|GBM:validation|KIRC:validation|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:validation|PRAD:TCGA|STAD:TCGA,breast cancer|carcinoid|cervical cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.019309448281860087,0.019309448281860087,0.0,0.02737581848205881,0.33506812617436654,0.3076923076923077,0.11832468165131664,0.32420703459249317,0.20588235294117652
WDR53,ENSG00000185798,72.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,72.1,3,14.5,47,72.1,7.5,6.1,10.7,8,14.5,39,4.972413793103448,False,1,0,Cancer-germline,10.1002/1878-0261.12900,Jamin2021_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,head and neck cancer|pancreatic cancer|renal cancer|stomach cancer|testis cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.48594799994858917,0.48594799994858917,0.0,0.40122351284767427,0.7089158205399819,0.3076923076923077,0.6327038328660293,0.8385861858072058,0.20588235294117652
DNAH14,ENSG00000185842,21.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,21.5,3,6.4,47,21.5,3.6,1.4,3.4,8,6.4,39,3.359375,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.11573021270142049,0.11573021270142049,0.0,0.13102553475447273,0.43871784244678047,0.3076923076923077,0.40553529806022925,0.6114176510014058,0.20588235294117652
TRIM69,ENSG00000185880,34.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,34.0,3,7.0,47,34.0,0.8,0.2,0.8,8,7.0,39,4.857142857142857,False,0,0,,,,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,renal cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0877745693140636,0.0877745693140636,0.0,0.10222214685290822,0.4099144545452159,0.3076923076923077,0.32763633130757414,0.5335186842487507,0.20588235294117652
SPACDR,ENSG00000185955,66.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,66.5,3,9.1,47,66.5,2.9,0.5,1.9,8,9.1,39,7.307692307692308,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.10924001924001925,0.10924001924001925,0.0,0.06907032747806924,0.37676263517037695,0.3076923076923077,0.30128345487038183,0.5071658078115584,0.20588235294117652
LEMD1,ENSG00000186007,53.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,53.6,3,14.5,47,53.6,0.6,0.1,14.5,8,3.6,39,3.6965517241379313,False,6,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Jamin2021_core|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.017216117216117217,0.017216117216117217,0.0,0.03809573190956975,0.34578803960187743,0.3076923076923077,0.08052369388686524,0.28640604682804177,0.20588235294117652
NBPF6,ENSG00000186086,2.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.6,3,2.7,47,2.6,0.0,0.5,0.8,8,2.7,39,0.9629629629629629,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|COAD:TCGA|COAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA,breast cancer|colorectal cancer|endometrial cancer|melanoma|pancreatic cancer|prostate cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.003663003663003663,0.31135531135531136,0.3076923076923077,0.06332274815569151,0.269205101096868,0.20588235294117652
UBL4B,ENSG00000186150,102.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,102.0,3,3.2,47,102.0,0.5,0.0,0.6,8,3.2,39,31.875,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|GBM:TCGA|GBM:validation|TGCT:TCGA,endometrial cancer|lung cancer|melanoma|ovarian cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009746811345897582,0.009746811345897582,0.0,0.015366499783553858,0.3230588074758616,0.3076923076923077,0.03763743063305806,0.24351978357423457,0.20588235294117652
KDM4D,ENSG00000186280,32.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,32.3,3,2.0,47,32.3,0.9,0.4,0.9,8,2.0,39,16.15,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,cervical cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.058333543256837206,0.058333543256837206,0.0,0.049189602412268885,0.3568819101045766,0.3076923076923077,0.14733569358426046,0.353218046525437,0.20588235294117652
AKAP14,ENSG00000186471,81.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,81.5,3,75.1,47,81.5,0.1,0.0,42.5,8,75.1,39,1.0852197070572571,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT,True,True,31,20,BRCA:TCGA|BRCA:validation|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PRAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,prostate cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.1248969452473252,0.3307792981885017,0.20588235294117652
SPATC1,ENSG00000186583,36.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,36.5,3,8.4,47,36.5,0.0,0.2,0.1,8,8.4,39,4.345238095238095,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT,True,False,31,0,BRCA:validation|COAD:validation|KICH:TCGA|KIRP:TCGA|LIHC:validation|READ:validation|STAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.039235099980586295,0.039235099980586295,0.0,0.014518532762847942,0.32221084045515563,0.3076923076923077,0.11927003327259081,0.3251523862137673,0.20588235294117652
KIF24,ENSG00000186638,10.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.9,3,4.2,47,10.9,0.6,0.6,3.2,8,4.2,39,2.5952380952380953,False,4,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer|glioma|melanoma|testis cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.10713899630206775,0.10713899630206775,0.0,0.08227744698332934,0.38996975467563705,0.3076923076923077,0.19841567950344668,0.4042980324446232,0.20588235294117652
PRG2,ENSG00000186652,2526.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2526.3,3,212.7,47,0.0,0.1,2526.3,0.4,8,212.7,39,11.877291960507758,False,0,0,,,,True,False,31,20,BRCA:validation|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|SKCM:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.18719214631228645,0.18719214631228645,0.0,0.04164419671369066,0.3493365044059984,0.3076923076923077,0.19312047464054943,0.39900282758172595,0.20588235294117652
TMEM232,ENSG00000186952,16.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.4,3,13.9,47,16.4,0.5,0.4,13.9,8,3.6,39,1.1798561151079134,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BRCA:TCGA|BRCA:validation|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|colorectal cancer|liver cancer|lung cancer|melanoma|ovarian cancer|prostate cancer|renal cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.08177117000646414,0.08177117000646414,0.0,0.06277877640753896,0.37047108409984664,0.3076923076923077,0.23025839284071914,0.43614074578189566,0.20588235294117652
EFCAB6,ENSG00000186976,23.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,23.6,3,7.4,47,23.6,1.2,0.2,7.4,8,3.1,39,3.189189189189189,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0674402281857145,0.0674402281857145,0.0,0.06137925961309475,0.36907156730540247,0.3076923076923077,0.1946595427307682,0.4005418956719447,0.20588235294117652
HEATR4,ENSG00000187105,11.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11.1,3,3.4,47,11.1,0.6,0.3,0.9,8,3.4,39,3.264705882352941,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09329760111630576,0.09329760111630576,0.0,0.050601407880387105,0.3582937155726948,0.3076923076923077,0.19405640798829654,0.39993876092947306,0.20588235294117652
H1-7,ENSG00000187166,211.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,211.0,3,0.7,47,211.0,0.8,0.0,0.3,8,0.7,39,301.42857142857144,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,True,29,20,,breast cancer|colorectal cancer|liver cancer|melanoma|pancreatic cancer|prostate cancer|renal cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.017589948600799547,0.017589948600799547,0.0,0.012253798114453852,0.3199461058067616,0.3076923076923077,0.0724375345219335,0.27831988746311,0.20588235294117652
FAM9C,ENSG00000187268,4.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.2,3,37.2,47,4.2,1.2,0.6,0.4,8,37.2,39,0.11290322580645161,False,4,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:validation|PAAD:validation|READ:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1596073166638698,0.1596073166638698,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.03987153672972528,0.24575388967090178,0.20588235294117652
POTEG,ENSG00000187537,1.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.8,3,1.1,47,0.8,0.0,0.0,1.1,8,0.0,39,0.7272727272727273,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,False,False,31,0,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
COX8C,ENSG00000187581,74.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,74.1,3,0.4,47,74.1,0.1,0.0,0.2,8,0.4,39,185.24999999999997,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BRCA:validation|GBM:validation|OV:TCGA|OV:validation|TGCT:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|melanoma|ovarian cancer|pancreatic cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.04020244461420932,0.24608479755538584,0.20588235294117652
LIAT1,ENSG00000187624,57.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,57.2,3,9.8,47,57.2,3.7,0.3,8.6,8,9.8,39,5.836734693877551,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2244868723283353,0.2244868723283353,0.0,0.181744656241716,0.4894369639340237,0.3076923076923077,0.471270231185297,0.6771525841264735,0.20588235294117652
FANCA,ENSG00000187741,21.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,21.0,3,11.3,47,21.0,1.3,1.8,2.7,8,11.3,39,1.8584070796460175,False,2,0,Cancer-germline,10.1038/s41388-018-0357-2|10.18632/oncotarget.21715,Bruggeman2018_GC|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.240332698985253,0.240332698985253,0.0,0.20450462832070382,0.5121969360130115,0.3076923076923077,0.4128653309667794,0.618747683907956,0.20588235294117652
C9orf153,ENSG00000187753,20.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,20.0,3,2.4,47,20.0,0.1,0.8,0.2,8,2.4,39,8.333333333333334,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:validation|COAD:validation|GBM:validation|KIRC:TCGA|KIRC:validation|LUAD:validation|LUSC:validation|READ:validation|STAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.017628776012952527,0.017628776012952527,0.0,0.015885333665913742,0.3235776413582214,0.3076923076923077,0.07468682212927737,0.28056917507045387,0.20588235294117652
LIN28B,ENSG00000187772,63.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,63.2,3,1.5,47,4.1,0.0,63.2,0.0,8,1.5,39,42.13333333333333,False,6,0,Cancer-germline|Cancer-placental|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.18632/oncotarget.21715,Bruggeman2018_GC|Carter2023_CT|Chang2019_TGCT|Gong2021_placenta_PC|Gong2021_reproductive_PC|Jamin2021_CT|Jamin2021_core|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,BLCA:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline|Cancer-placental,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009862162686856923,0.009862162686856923,0.0,0.0037831021437578823,0.3114754098360656,0.3076923076923077,0.037997531028221565,0.24387988396939808,0.20588235294117652
FANCM,ENSG00000187790,6.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.5,3,3.3,47,6.5,2.0,1.1,1.8,8,3.3,39,1.9696969696969697,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1421327210800895,0.1421327210800895,0.0,0.12180256410506192,0.4294948717973696,0.3076923076923077,0.30720862031978213,0.5130909732609586,0.20588235294117652
CCDC157,ENSG00000187860,26.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,26.8,3,7.5,47,26.8,1.2,0.5,7.5,8,6.2,39,3.5733333333333333,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|lung cancer|ovarian cancer|pancreatic cancer|prostate cancer|skin cancer|stomach cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.12700219970877097,0.12700219970877097,0.0,0.102638487373287,0.4103307950655947,0.3076923076923077,0.34583420755360755,0.551716560494784,0.20588235294117652
PRR19,ENSG00000188368,21.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,21.0,3,4.1,47,21.0,0.8,0.3,0.7,8,4.1,39,5.121951219512195,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04751634658176714,0.04751634658176714,0.0,0.047700063160483974,0.3553923708527917,0.3076923076923077,0.18956984088277304,0.3954521938239496,0.20588235294117652
H3-5,ENSG00000188375,21.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,21.2,3,3.1,47,21.2,0.9,0.3,0.6,8,3.1,39,6.838709677419354,False,0,0,,,,True,True,29,20,CESC:TCGA|GBM:validation|KIRP:TCGA|OV:validation|PAAD:validation|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.056424217218917966,0.056424217218917966,0.0,0.03329790743094652,0.3409902151232542,0.3076923076923077,0.14164005180123418,0.3475224047424107,0.20588235294117652
FSIP2,ENSG00000188738,5.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,True,False,False,False,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.2,3,2.5,47,5.2,0.2,0.1,0.1,8,2.5,39,2.08,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1371/journal.pgen.1011734,Chang2019_TGCT|Loriot2025_S2,True,False,30,0,COAD:validation|GBM:validation|KIRC:TCGA|KIRC:validation|OV:validation|PAAD:validation|READ:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.011803533294505923,0.011803533294505923,0.0,0.05343470696245518,0.3611270146547629,0.3076923076923077,0.027956272201796497,0.23383862514297302,0.20588235294117652
RBM34,ENSG00000188739,20.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,20.7,3,35.0,47,20.7,12.2,12.8,16.5,8,35.0,39,0.5914285714285714,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.5904435638199086,0.5904435638199086,0.0,0.48280011477675455,0.7904924224690623,0.3076923076923077,0.6879958778720004,0.893878230813177,0.20588235294117652
BEND4,ENSG00000188848,9.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,True,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.1,3,3.0,47,9.1,0.1,0.2,3.0,8,1.7,39,3.033333333333333,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,31,20,BRCA:validation|COAD:validation|GBM:validation|LUSC:TCGA|LUSC:validation|PRAD:TCGA|TGCT:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Antibody concern|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03463463463463464,0.03463463463463464,0.0,0.025688219765427595,0.3333805274577353,0.3076923076923077,0.07631837884086048,0.282200731782037,0.20588235294117652
NKAPL,ENSG00000189134,31.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,31.4,3,12.2,47,31.4,1.6,0.8,2.4,8,12.2,39,2.5737704918032787,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09087564984247387,0.09087564984247387,0.0,0.12177900565041166,0.4294713133427194,0.3076923076923077,0.3626782085442499,0.5685605614854264,0.20588235294117652
TRIM64B,ENSG00000189253,3.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,True,False,False,True,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.5,3,0.0,47,0.0,0.0,3.5,0.0,8,0.0,39,,True,0,0,,,,True,False,30,20,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
DRICH1,ENSG00000189269,45.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,45.1,3,16.5,47,45.1,1.9,0.8,16.5,8,8.9,39,2.7333333333333334,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1473011150262582,0.1473011150262582,0.0,0.13005122623797866,0.43774353393028637,0.3076923076923077,0.2823700828596079,0.4882524358007844,0.20588235294117652
SYCP2,ENSG00000196074,41.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,41.8,3,13.5,47,41.8,0.7,3.8,13.5,8,6.4,39,3.096296296296296,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Jamin2021_core|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.19640899900928738,0.19640899900928738,0.0,0.16453478630560486,0.4722270939979126,0.3076923076923077,0.3770085586475847,0.5828909115887613,0.20588235294117652
PLEKHG4,ENSG00000196155,41.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,41.1,3,9.2,47,41.1,16.8,4.9,9.2,8,8.7,39,4.467391304347826,False,0,0,,,,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.3874746261159093,0.3874746261159093,0.0,0.24561018135630483,0.5533024890486126,0.3076923076923077,0.4319074495729938,0.6377898025141704,0.20588235294117652
GREB1,ENSG00000196208,269.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,269.4,3,61.5,47,14.5,269.4,2.9,61.5,8,12.3,39,4.380487804878048,False,0,0,,,,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,carcinoid|colorectal cancer|endometrial cancer|liver cancer|melanoma|pancreatic cancer|renal cancer|stomach cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.08910756610817057,0.08910756610817057,0.0,0.12072078654913054,0.42841309424143825,0.3076923076923077,0.47242603570069314,0.6783083886418697,0.20588235294117652
STK31,ENSG00000196335,62.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,62.2,3,1.3,47,62.2,0.6,0.0,0.2,8,1.3,39,47.84615384615385,False,6,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Jamin2021_core|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|HNSC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.015725101921956905,0.015725101921956905,0.0,0.014694509174942808,0.3223868168672505,0.3076923076923077,0.07136914181712466,0.2772514947583012,0.20588235294117652
INCA1,ENSG00000196388,46.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,46.4,3,10.4,47,46.4,4.8,2.9,5.0,8,10.4,39,4.461538461538462,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.3059854644721117,0.3059854644721117,0.0,0.26268171562434983,0.5703740233166575,0.3076923076923077,0.5164219246522784,0.722304277593455,0.20588235294117652
CRYBA4,ENSG00000196431,1.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.1,3,1.4,47,1.1,0.0,0.0,1.4,8,0.2,39,0.7857142857142858,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BRCA:validation|GBM:validation|PRAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005901766647252961,0.005901766647252961,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.0049019607843137246,0.21078431372549025,0.20588235294117652
CCDC196,ENSG00000196553,5.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.3,3,0.1,47,5.3,0.0,0.0,0.0,8,0.1,39,52.99999999999999,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734,Gong2021_reproductive_PC|Loriot2025_S2,True,False,29,0,BRCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0003501400560224089,0.20623249299719892,0.20588235294117652
HBG2,ENSG00000196565,9951.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9951.4,3,77.0,47,0.8,2.4,9951.4,4.0,8,77.0,39,129.23896103896104,False,0,0,Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_placenta_PC|Gong2021_reproductive_PC,True,True,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PAAD:validation|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,liver cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.3477946831262209,0.3477946831262209,0.0,0.1238997568846466,0.4315920645769543,0.3076923076923077,0.5372074353070638,0.7430897882482403,0.20588235294117652
CLPSL2,ENSG00000196748,518.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.3,3,518.4,47,0.3,0.0,0.0,518.4,8,5.0,39,0.0005787037037037037,False,1,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_CT|daSilva2017_testis_biased,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|OV:TCGA|PAAD:TCGA|READ:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|colorectal cancer|lung cancer|prostate cancer|renal cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,False,True,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005901766647252961,0.005901766647252961,0.0,0.01619433198380567,0.32388663967611336,0.3076923076923077,0.05439291101055807,0.2602752639517346,0.20588235294117652
TOMM20L,ENSG00000196860,10.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.6,3,1.0,47,10.6,0.3,0.2,1.0,8,0.5,39,10.6,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BRCA:TCGA|BRCA:validation|COAD:validation|GBM:validation|LIHC:validation|PRAD:TCGA|READ:TCGA|READ:validation|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.023192189497158087,0.023192189497158087,0.0,0.020572927492851834,0.32826523518515954,0.3076923076923077,0.05179858504666689,0.2576809379878434,0.20588235294117652
NPIPB9,ENSG00000196993,13.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.1,3,2.6,47,13.1,2.2,0.0,1.5,8,2.6,39,5.038461538461538,False,0,0,,,,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.08898858805400862,0.08898858805400862,0.0,0.04683837740790638,0.35453068510021407,0.3076923076923077,0.22745100152079775,0.4333333544619743,0.20588235294117652
ZNF257,ENSG00000197134,2.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.6,3,4.1,47,2.6,2.3,2.0,1.5,8,4.1,39,0.6341463414634148,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT|Jamin2021_core,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1172755585552947,0.1172755585552947,0.0,0.0804353773895207,0.3881276850818284,0.3076923076923077,0.20212648178458018,0.40800883472575666,0.20588235294117652
ADAM32,ENSG00000197140,26.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,26.6,3,1.7,47,26.6,0.6,0.1,0.9,8,1.7,39,15.647058823529413,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|KICH:TCGA|KIRP:TCGA|LIHC:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04318356842712717,0.04318356842712717,0.0,0.03122563293463916,0.33891794062694686,0.3076923076923077,0.13778004102657954,0.34366239396775605,0.20588235294117652
PIWIL2,ENSG00000197181,27.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,27.9,3,5.8,47,27.9,1.4,0.1,1.2,8,5.8,39,4.810344827586206,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRP:TCGA|LIHC:validation|LUSC:TCGA|LUSC:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04840168039990881,0.04840168039990881,0.0,0.06782678717534593,0.37551909486765367,0.3076923076923077,0.21998199133565632,0.42586434427683284,0.20588235294117652
ZSCAN5B,ENSG00000197213,1.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.7,3,0.3,47,1.7,0.0,0.0,0.1,8,0.3,39,5.666666666666667,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,TGCT:TCGA,breast cancer|colorectal cancer|liver cancer|melanoma|ovarian cancer|prostate cancer|stomach cancer|urothelial cancer,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0019776685377708393,0.20786002147894736,0.20588235294117652
ZNF165,ENSG00000197279,19.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,19.2,3,6.6,47,19.2,0.8,3.9,6.6,8,6.2,39,2.909090909090909,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.12316045057310485,0.12316045057310485,0.0,0.2087118439831112,0.516404151675419,0.3076923076923077,0.3503945498364153,0.5562769027775918,0.20588235294117652
FABP12,ENSG00000197416,7.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.2,3,54.5,47,7.2,0.0,0.0,1.9,8,54.5,39,0.13211009174311927,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,31,20,BRCA:validation|CESC:TCGA|GBM:validation|HNSC:TCGA,lung cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.026785714285714288,0.334478021978022,0.3076923076923077,0.04619733618726444,0.252079689128441,0.20588235294117652
IFT70A,ENSG00000197557,9.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.6,3,8.0,47,9.6,2.2,0.9,7.7,8,8.0,39,1.2,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT|Jamin2021_core,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,liver cancer|lung cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1852021466803237,0.1852021466803237,0.0,0.18531515158337494,0.4930074592756827,0.3076923076923077,0.4033482503060431,0.6092306032472197,0.20588235294117652
KCNMB2,ENSG00000197584,34.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.7,3,34.5,47,0.2,10.7,0.1,34.5,8,5.6,39,0.31014492753623185,False,1,0,Cancer-germline,10.1038/s41388-018-0357-2,Bruggeman2018_GC,True,True,31,20,BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|TGCT:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|pancreatic cancer|prostate cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,False,True,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03509695140192,0.03509695140192,0.0,0.05293802584547766,0.3606303335377854,0.3076923076923077,0.316012450387176,0.5218948033283526,0.20588235294117652
CFAP43,ENSG00000197748,55.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,55.6,3,96.9,47,55.6,1.8,0.3,47.4,8,96.9,39,0.5737874097007224,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.10237393313767414,0.10237393313767414,0.0,0.060642781715712996,0.36833508940802073,0.3076923076923077,0.3231953300741898,0.5290776830153663,0.20588235294117652
STPG3,ENSG00000197768,41.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,41.3,3,3.8,47,41.3,0.0,0.2,0.4,8,3.8,39,10.868421052631579,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,29,0,BRCA:TCGA|COAD:validation|GBM:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|OV:TCGA|OV:validation|PRAD:TCGA|READ:validation|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.058535673434700855,0.058535673434700855,0.0,0.025800861659142166,0.3334931693514499,0.3076923076923077,0.15434896102745288,0.3602313139686294,0.20588235294117652
CFAP299,ENSG00000197826,26.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,26.6,3,19.2,47,26.6,0.5,0.0,19.2,8,5.1,39,1.3854166666666667,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,29,20,GBM:validation|KIRC:TCGA|KIRC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|PRAD:TCGA|UCEC:TCGA,breast cancer|cervical cancer|liver cancer|melanoma|pancreatic cancer|stomach cancer|testis cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013484205563413485,0.013484205563413485,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.08003245618104887,0.2859148091222254,0.20588235294117652
MEIG1,ENSG00000197889,9.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.9,3,3.5,47,9.9,0.0,0.1,3.5,8,1.1,39,2.8285714285714287,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|GBM:TCGA|GBM:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|OV:TCGA|OV:validation|PAAD:validation|PRAD:TCGA|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013744903902154923,0.013744903902154923,0.0,0.012528983443843308,0.320221291136151,0.3076923076923077,0.09530945063374532,0.3011918035749218,0.20588235294117652
NPIPB6,ENSG00000198156,38.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,38.6,3,3.7,47,38.6,3.1,0.1,2.8,8,3.7,39,10.432432432432432,False,0,0,,,,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.12849399604036238,0.12849399604036238,0.0,0.07630355918365073,0.38399586687595844,0.3076923076923077,0.2918584471602002,0.4977408001013767,0.20588235294117652
OXCT2,ENSG00000198754,71.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,71.0,3,6.3,47,71.0,2.2,0.2,1.2,8,6.3,39,11.26984126984127,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.15710559964102058,0.15710559964102058,0.0,0.04555188812138207,0.35324419581368977,0.3076923076923077,0.2317730475090342,0.43765540045021073,0.20588235294117652
EGFL6,ENSG00000198759,623.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,623.7,3,24.8,47,0.3,0.4,623.7,3.1,8,24.8,39,25.1491935483871,False,0,0,,10.1158/0008-5472.CAN-16-0225,Bai2016_EGFL6,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,prostate cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1572992534186622,0.1572992534186622,0.0,0.13063841170967763,0.4383307194019853,0.3076923076923077,0.1847775766087023,0.3906599295498788,0.20588235294117652
PNMA5,ENSG00000198883,8.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,8.5,3,21.7,47,8.5,0.0,0.1,0.0,8,21.7,39,0.391705069124424,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|CESC:TCGA|GBM:validation|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUSC:TCGA|LUSC:validation|STAD:TCGA|TGCT:TCGA,testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013445378151260505,0.013445378151260505,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.0715197125859097,0.27740206552708624,0.20588235294117652
ITPRIPL1,ENSG00000198885,27.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,27.0,3,7.3,47,27.0,0.4,1.2,3.6,8,7.3,39,3.6986301369863015,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.18069559368355645,0.18069559368355645,0.0,0.15740440743193446,0.46509671512424217,0.3076923076923077,0.24202242768949622,0.44790478063067274,0.20588235294117652
DCAF12L1,ENSG00000198889,6.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.0,3,4.8,47,6.0,0.6,0.0,4.8,8,1.5,39,1.25,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,True,31,20,BRCA:validation|CESC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|OV:TCGA|OV:validation|SKCM:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.024083584829071147,0.024083584829071147,0.0,0.011531163333819882,0.3192234710261276,0.3076923076923077,0.033708938120702824,0.23959129106187935,0.20588235294117652
FAM229B,ENSG00000203778,435.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,435.6,3,101.6,47,435.6,28.9,10.2,51.6,8,101.6,39,4.28740157480315,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.5179233341475287,0.5179233341475287,0.0,0.4476380015706375,0.7553303092629452,0.3076923076923077,0.7069072779695104,0.9127896309106869,0.20588235294117652
FANK1,ENSG00000203780,54.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,54.9,3,66.4,47,54.9,5.2,1.2,33.9,8,66.4,39,0.8268072289156626,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.20910972139183634,0.20910972139183634,0.0,0.20856419442194754,0.5162565021142552,0.3076923076923077,0.4111158305257864,0.6169981834669629,0.20588235294117652
LELP1,ENSG00000203784,1086.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1086.6,3,0.9,47,1086.6,0.1,0.0,0.9,8,0.4,39,1207.3333333333333,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.017591079496299143,0.017591079496299143,0.0,0.00630517023959647,0.3139974779319042,0.3076923076923077,0.04507395843712979,0.2509563113783063,0.20588235294117652
HSD3B1,ENSG00000203857,75.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,75.2,3,8.4,47,0.0,0.0,75.2,1.4,8,8.4,39,8.952380952380953,False,0,0,Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_placenta_PC|Gong2021_reproductive_PC,True,False,31,20,BLCA:TCGA|BRCA:validation|COAD:TCGA|COAD:validation|LIHC:TCGA|LIHC:validation|READ:TCGA|READ:validation|SKCM:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06802182480691508,0.06802182480691508,0.0,0.009731730018615265,0.317424037710923,0.3076923076923077,0.1270676508816926,0.3329500038228691,0.20588235294117652
C1orf141,ENSG00000203963,14.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,14.9,3,8.9,47,14.9,0.5,0.0,8.9,8,3.1,39,1.6741573033707864,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,False,31,0,LUAD:TCGA|LUAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.057142409841791766,0.26302476278296827,0.20588235294117652
LRRC73,ENSG00000204052,43.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,43.0,3,12.5,47,43.0,0.9,0.2,6.1,8,12.5,39,3.44,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,cervical cancer|prostate cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.037452439051525295,0.037452439051525295,0.0,0.05853521855045694,0.36622752624276467,0.3076923076923077,0.2784909470842409,0.4843733000254174,0.20588235294117652
RPA4,ENSG00000204086,1.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.6,3,0.4,47,1.6,0.2,0.2,0.4,8,0.4,39,4.0,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BRCA:validation|COAD:validation|GBM:validation|PAAD:validation|READ:validation|TGCT:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013632901751713633,0.013632901751713633,0.0,0.00878655981776024,0.31647886751006793,0.3076923076923077,0.05051842871535966,0.2564007816565362,0.20588235294117652
CXorf65,ENSG00000204165,21.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,True,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,21.8,3,2.2,47,21.8,0.0,0.0,0.1,8,2.2,39,9.909090909090908,False,1,0,Cancer-germline,10.1002/1878-0261.12900,Jamin2021_CT,True,True,31,20,BRCA:validation|GBM:validation|LIHC:validation|PAAD:validation|SKCM:TCGA,testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Antibody concern|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04394753843754676,0.04394753843754676,0.0,0.010006915348004719,0.31769922304031245,0.3076923076923077,0.058002402404679444,0.263884755345856,0.20588235294117652
PJVK,ENSG00000204311,26.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,26.6,3,7.1,47,26.6,5.7,1.2,7.1,8,6.2,39,3.746478873239437,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.20799549115430271,0.20799549115430271,0.0,0.15673904694098925,0.464431354633297,0.3076923076923077,0.45075561433115874,0.6566379672723353,0.20588235294117652
HSPA1L,ENSG00000204390,61.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,61.4,3,3.8,47,61.4,2.1,0.0,2.3,8,3.8,39,16.157894736842106,False,1,0,Cancer-germline,10.1038/s41388-018-0357-2,Bruggeman2018_GC,True,False,31,20,BRCA:validation|COAD:validation|GBM:validation|LIHC:validation|OV:TCGA|OV:validation|PAAD:validation|READ:validation|STAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.10113021522880371,0.10113021522880371,0.0,0.06524091381727275,0.37293322150958047,0.3076923076923077,0.2953660761384005,0.501248429079577,0.20588235294117652
CSHL1,ENSG00000204414,145.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,145.3,3,0.8,47,0.1,0.0,145.3,0.1,8,0.8,39,181.625,False,1,0,Cancer-germline|Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_placenta_PC|Gong2021_reproductive_PC|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.005901766647252961,0.005901766647252961,0.0,0.004924037710922957,0.3126163454032307,0.3076923076923077,0.037084398976982104,0.2429667519181586,0.20588235294117652
CCHCR1,ENSG00000204536,135.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,135.1,3,19.3,47,135.1,18.4,0.9,19.3,8,19.1,39,6.999999999999999,False,1,0,Cancer-germline,10.1002/1878-0261.12900,Jamin2021_CT|Jamin2021_core,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.4957772921211513,0.4957772921211513,0.0,0.3577281606804555,0.6654204683727631,0.3076923076923077,0.6018146833492027,0.8076970362903793,0.20588235294117652
PSORS1C1,ENSG00000204540,106.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,106.8,3,3.2,47,106.8,0.7,0.0,2.3,8,3.2,39,33.375,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.08367234744365036,0.08367234744365036,0.0,0.057640860664482076,0.3653331683567898,0.3076923076923077,0.12071662205538532,0.3265989749965618,0.20588235294117652
CBY3,ENSG00000204659,15.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.0,3,3.0,47,15.0,0.7,0.0,0.7,8,3.0,39,5.0,False,1,0,Cancer-germline,10.1002/cam4.2223,Chang2019_TGCT,True,True,30,20,KIRC:validation|OV:validation,breast cancer|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.028759873755186408,0.028759873755186408,0.0,0.02748833052803276,0.3351806382203405,0.3076923076923077,0.1586664174759181,0.3645487704170946,0.20588235294117652
KRT25,ENSG00000204897,2.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.8,3,108.8,47,0.8,0.0,0.0,2.6,8,108.8,39,0.007352941176470589,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,False,False,31,20,,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2244348244348245,0.2244348244348245,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.005952380952380952,0.21183473389355748,0.20588235294117652
FAM221B,ENSG00000204930,9.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.5,3,2.8,47,9.5,0.0,0.0,0.6,8,2.8,39,3.3928571428571432,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|KICH:TCGA|KIRC:TCGA|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,prostate cancer|renal cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.017628776012952527,0.017628776012952527,0.0,0.030080944289950517,0.3377732519822582,0.3076923076923077,0.07734552318951296,0.28322787613068945,0.20588235294117652
PSG5,ENSG00000204941,108.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,108.6,3,0.8,47,0.0,0.0,108.6,0.1,8,0.8,39,135.74999999999997,False,0,0,Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_placenta_PC|Gong2021_reproductive_PC,True,False,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|HNSC:TCGA|KICH:TCGA|LUSC:TCGA|LUSC:validation|PAAD:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013445378151260505,0.013445378151260505,0.0,0.0074054272890867285,0.31509773498139443,0.3076923076923077,0.035559006211180126,0.24144135915235665,0.20588235294117652
PCDHA4,ENSG00000204967,0.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.3,3,2.0,47,0.3,0.1,0.1,0.5,8,2.0,39,0.15,False,2,0,Cancer-germline,10.1038/s41388-018-0357-2|10.18632/oncotarget.21715,Bruggeman2018_GC|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.021437211594462616,0.021437211594462616,0.0,0.019853053697580402,0.3275453613898881,0.3076923076923077,0.130895459219165,0.3367778121603415,0.20588235294117652
PCDHA1,ENSG00000204970,1.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.0,3,2.8,47,1.0,0.0,0.0,0.1,8,2.8,39,0.35714285714285715,False,2,0,Cancer-germline,10.1038/s41388-018-0357-2|10.18632/oncotarget.21715,Bruggeman2018_GC|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PRAD:TCGA|SKCM:TCGA|UCEC:TCGA,endometrial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.09620437688305422,0.30208672982423074,0.20588235294117652
SYCE1L,ENSG00000205078,22.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,22.8,3,6.8,47,22.8,5.1,0.5,6.8,8,4.9,39,3.3529411764705883,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.17566954244585825,0.17566954244585825,0.0,0.12416876829651463,0.43186107598882234,0.3076923076923077,0.3483815331816689,0.5542638861228455,0.20588235294117652
GARIN1A,ENSG00000205085,35.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,35.4,3,4.3,47,35.4,1.8,0.2,2.1,8,4.3,39,8.232558139534884,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.12973652577612976,0.12973652577612976,0.0,0.08804583288091089,0.3957381405732186,0.3076923076923077,0.3646602918888884,0.5705426448300649,0.20588235294117652
CFAP96,ENSG00000205129,11.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11.6,3,30.8,47,11.6,0.8,0.2,11.4,8,30.8,39,0.3766233766233766,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09203673661539571,0.09203673661539571,0.0,0.02912656368296445,0.33681887137527217,0.3076923076923077,0.2507127564008354,0.4565951093420119,0.20588235294117652
ARRDC5,ENSG00000205784,16.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.5,3,2.1,47,16.5,0.0,0.0,0.2,8,2.1,39,7.857142857142857,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:validation|COAD:validation|GBM:validation|KIRC:TCGA|KIRC:validation|PAAD:TCGA|READ:validation|STAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06823754475761055,0.06823754475761055,0.0,0.02821028786126618,0.3359025955535739,0.3076923076923077,0.08033148882650602,0.28621384176768255,0.20588235294117652
C22orf42,ENSG00000205856,10.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.3,3,9.3,47,10.3,0.0,0.0,0.7,8,9.3,39,1.10752688172043,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Jamin2021_CT|Jamin2021_core|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,PAAD:TCGA|PRAD:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.003663003663003663,0.31135531135531136,0.3076923076923077,0.04005674613430991,0.24593909907548642,0.20588235294117652
TMEM191C,ENSG00000206140,49.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,49.3,3,2.5,47,49.3,0.2,0.0,0.6,8,2.5,39,19.72,False,0,0,,,,True,False,30,0,BLCA:TCGA|KICH:TCGA|KIRP:TCGA|LIHC:validation|OV:TCGA|OV:validation|PAAD:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04314125030877964,0.04314125030877964,0.0,0.02591174973376534,0.3336040574260731,0.3076923076923077,0.11927768131020572,0.32516003425138224,0.20588235294117652
ELOA2,ENSG00000206181,3.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3.9,3,0.0,47,3.9,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,False,True,29,20,,colorectal cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|skin cancer|stomach cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
CD200R1L,ENSG00000206531,2.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.7,3,0.0,47,2.7,0.0,0.0,0.0,8,0.0,39,,True,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,COAD:validation|LUSC:validation|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
PRR22,ENSG00000212123,48.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,48.7,3,11.6,47,48.7,3.2,0.9,6.8,8,11.6,39,4.198275862068966,False,1,0,Cancer-germline,10.1038/ncomms10499,Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2702554608849933,0.2702554608849933,0.0,0.17475433980839705,0.48244664750070476,0.3076923076923077,0.454003724752884,0.6598860776940605,0.20588235294117652
CGB8,ENSG00000213030,18.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,18.1,3,2.3,47,0.0,0.0,18.1,0.0,8,2.3,39,7.8695652173913055,False,1,0,Cancer-germline|Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_placenta_PC|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|HNSC:TCGA|LUAD:TCGA|LUSC:TCGA|PAAD:TCGA|PAAD:validation|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.03146374829001368,0.2373461012311902,0.20588235294117652
CSH2,ENSG00000213218,3198.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,3198.1,3,14.6,47,0.2,0.0,3198.1,2.0,8,14.6,39,219.04794520547946,False,2,0,Cancer-germline|Cancer-placental|Cancer-reproductive,10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_placenta_PC|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,TGCT:TCGA,,True,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline|Cancer-placental,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.10948616600790516,0.10948616600790516,0.0,0.03870745859111804,0.3463997662834257,0.3076923076923077,0.14110499684674943,0.34698734978792595,0.20588235294117652
TCL1B,ENSG00000213231,2.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,True,False,True,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.5,3,2.4,47,2.5,0.2,0.8,0.6,8,2.4,39,1.0416666666666667,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BRCA:TCGA|BRCA:validation|TGCT:TCGA|UCEC:TCGA,breast cancer|endometrial cancer|glioma|liver cancer|melanoma|prostate cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Antibody concern|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.01506431016933469,0.01506431016933469,0.0,0.019943019943019946,0.32763532763532766,0.3076923076923077,0.035438691605674526,0.24132104454685105,0.20588235294117652
MAGEA12,ENSG00000213401,2.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,True,False,False,False,False,False,False,False,Unsafe,Safety,An applicable reviewed safety veto excludes unrestricted targeting,An applicable reviewed safety veto excludes unrestricted targeting; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Safety,An applicable reviewed safety veto excludes unrestricted targeting,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,2.7,3,0.5,47,2.7,0.0,0.0,0.0,8,0.5,39,5.4,False,6,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1136/jitc-2023-007935|10.1186/s12967-024-04918-0|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Carter2023_CT|Chang2019_TGCT|Jamin2021_CT|Jamin2021_core|Loriot2025_S1|Seager2024_CTA|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Safety veto|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.009126615072906633,0.21500896801408315,0.20588235294117652
FAM209B,ENSG00000213714,111.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,111.2,3,11.6,47,111.2,0.2,0.1,0.7,8,11.6,39,9.586206896551724,False,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC,True,False,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:validation|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|PAAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09525644865267509,0.09525644865267509,0.0,0.05638820896180086,0.36408051665410857,0.3076923076923077,0.21163996871128166,0.4175223216524582,0.20588235294117652
HBG1,ENSG00000213934,357.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,357.1,3,5.4,47,0.2,0.4,357.1,1.0,8,5.4,39,66.12962962962963,False,0,0,,,,True,True,31,20,BRCA:validation|GBM:TCGA|GBM:validation|KIRC:TCGA,liver cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.13503870236668888,0.13503870236668888,0.0,0.03991286669146048,0.3476051743837682,0.3076923076923077,0.2126724547476016,0.4185548076887781,0.20588235294117652
CDRT15L2,ENSG00000214819,15.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.1,3,2.2,47,15.1,0.0,0.0,0.9,8,2.2,39,6.863636363636363,False,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,30,0,CESC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.004201680672268908,0.21008403361344544,0.20588235294117652
TBC1D26,ENSG00000214946,15.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.4,3,4.2,47,15.4,0.3,0.0,0.4,8,4.2,39,3.6666666666666665,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.18632/oncotarget.21715,Chang2019_TGCT|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.002522068095838588,0.3102143757881463,0.3076923076923077,0.03960553006449591,0.24548788300567242,0.20588235294117652
GAGE12G,ENSG00000215269,60.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,60.1,3,5.9,47,60.1,0.1,0.0,0.0,8,5.9,39,10.186440677966102,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.18632/oncotarget.21715,Jamin2021_CT|Jamin2021_core|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,30,20,LUSC:TCGA|OV:TCGA|OV:validation|SKCM:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.03813833225597932,0.345830639948287,0.3076923076923077,0.00980392156862745,0.21568627450980396,0.20588235294117652
C1orf167,ENSG00000215910,27.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,27.4,3,0.5,47,27.4,0.2,0.0,0.2,8,0.5,39,54.8,False,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,29,20,BRCA:TCGA|OV:validation|PAAD:validation|PRAD:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.013707207385501543,0.013707207385501543,0.0,0.00630517023959647,0.3139974779319042,0.3076923076923077,0.05243188184364655,0.25831423478482307,0.20588235294117652
CCDC7,ENSG00000216937,76.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,76.9,3,2.6,47,76.9,0.9,0.6,1.1,8,2.6,39,29.576923076923077,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0797593474200471,0.0797593474200471,0.0,0.08413969161173775,0.39183199930404544,0.3076923076923077,0.24927367655728264,0.4551560294984591,0.20588235294117652
SYCE3,ENSG00000217442,138.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,138.1,3,2.7,47,138.1,0.0,0.3,1.5,8,2.7,39,51.148148148148145,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06501232971821208,0.06501232971821208,0.0,0.04372337939488003,0.35141568708718773,0.3076923076923077,0.20950255872423917,0.4153849116654157,0.20588235294117652
PAPOLB,ENSG00000218823,29.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,29.0,3,0.2,47,29.0,0.0,0.0,0.0,8,0.2,39,145.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,GBM:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.00267379679144385,0.20855614973262038,0.20588235294117652
CATSPERZ,ENSG00000219435,570.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,570.0,3,3.3,47,570.0,0.1,0.8,0.9,8,3.3,39,172.72727272727275,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,False,29,0,BLCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUSC:TCGA|LUSC:validation|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04928289532249929,0.04928289532249929,0.0,0.026756062179423855,0.33444836987173154,0.3076923076923077,0.10725324981370005,0.31313560275487656,0.20588235294117652
MAGEA3,ENSG00000221867,7.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,False,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.8,3,0.2,47,7.8,0.0,0.3,0.0,8,0.2,39,39.0,False,7,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.1136/jitc-2023-007935|10.1186/s12967-024-04918-0|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Bruggeman2018_GC|Carter2023_CT|Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Jamin2021_core|Loriot2025_S1|Seager2024_CTA|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,Context only,"User excluded non-MAGEA4 MAGE genes from positive controls and automatic reviewed admission; retain citations and concerns, and evaluate ordinary publication/expression routes.",https://pubmed.ncbi.nlm.nih.gov/23377668/,"Severe neurological toxicity is retained; the receptor also recognizes MAGE-A9/A12, so causal normal-tissue antigen attribution is family-confounded.",Locus,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.003921568627450981,0.003921568627450981,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
XKR9,ENSG00000221947,7.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.1,3,5.2,47,7.1,0.2,0.4,1.2,8,5.2,39,1.3653846153846152,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|colorectal cancer|endometrial cancer|melanoma|prostate cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.039741514107407255,0.039741514107407255,0.0,0.06387022731969269,0.37156253501200043,0.3076923076923077,0.1911936818555497,0.3970760347967262,0.20588235294117652
GAGE12J,ENSG00000224659,22.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,22.5,3,2.2,47,22.5,0.1,0.0,0.7,8,2.2,39,10.227272727272727,False,5,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1186/s12967-024-04918-0|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Jamin2021_CT|Jamin2021_core|Loriot2025_S2|Seager2024_CTA|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.015406162464985995,0.2212885154061625,0.20588235294117652
FAM229A,ENSG00000225828,116.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,116.4,3,9.7,47,116.4,9.1,0.1,6.7,8,9.7,39,12.000000000000002,False,1,0,Cancer-germline,10.1002/cam4.2223,Chang2019_TGCT,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUSC:TCGA|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2923056010121122,0.2923056010121122,0.0,0.14851479936069634,0.45620710705300405,0.3076923076923077,0.47561385192326505,0.6814962048644415,0.20588235294117652
DCAF8L1,ENSG00000226372,0.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.9,3,0.0,47,0.9,0.0,0.0,0.0,8,0.0,39,,True,2,0,Cancer-germline|Cancer-reproductive,10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,LIHC:TCGA|LIHC:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.0,0.20588235294117652,0.20588235294117652
SRRM5,ENSG00000226763,46.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,46.5,3,2.6,47,46.5,0.8,0.2,1.9,8,2.6,39,17.884615384615383,False,0,0,,,,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|cervical cancer|colorectal cancer|glioma|liver cancer|ovarian cancer|pancreatic cancer|prostate cancer|stomach cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06092170098085395,0.06092170098085395,0.0,0.058820376173211474,0.36651268386551916,0.3076923076923077,0.22406679549199426,0.4299491484331708,0.20588235294117652
BOD1L2,ENSG00000228075,268.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,True,False,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Uncertain normal antibody evidence requires review,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,268.7,3,0.2,47,268.7,0.0,0.0,0.2,8,0.1,39,1343.4999999999998,False,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,False,True,29,20,,breast cancer|carcinoid|colorectal cancer|endometrial cancer|liver cancer|lung cancer|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Antibody concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.005602240896358543,0.21148459383753507,0.20588235294117652
CT45A5,ENSG00000228836,5.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,5.0,3,4.8,47,5.0,0.0,0.0,0.2,8,4.8,39,1.0416666666666667,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Jamin2021_CT|Jamin2021_core|Loriot2025_S1|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|GBM:TCGA|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,ovarian cancer|stomach cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.007920792079207921,0.007920792079207921,0.0,0.0037831021437578823,0.3114754098360656,0.3076923076923077,0.10045437765461837,0.3063367305957949,0.20588235294117652
CCDC192,ENSG00000230561,13.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.3,3,3.2,47,13.3,1.0,0.2,0.9,8,3.2,39,4.15625,False,0,0,,,,True,False,29,0,BLCA:TCGA|COAD:validation|GBM:validation|LUSC:validation|PAAD:validation|READ:TCGA|READ:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.028240770833589474,0.028240770833589474,0.0,0.021458658718745197,0.3291509664110529,0.3076923076923077,0.07129283759718542,0.2771751905383619,0.20588235294117652
CCDC188,ENSG00000234409,39.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,39.1,3,9.3,47,39.1,0.3,0.6,1.3,8,9.3,39,4.204301075268817,False,1,0,Cancer-germline,10.1002/cam4.2223,Chang2019_TGCT,True,False,29,0,BLCA:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:TCGA|READ:validation|SKCM:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.08167648594227758,0.08167648594227758,0.0,0.03533476187035314,0.3430270695626608,0.3076923076923077,0.20971837734562976,0.4156007302868063,0.20588235294117652
C5orf58,ENSG00000234511,208.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,208.8,3,7.5,47,208.8,0.6,1.1,2.4,8,7.5,39,27.84,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|COAD:validation|KIRC:TCGA|KIRC:validation|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.13103322094147782,0.13103322094147782,0.0,0.06727659041299838,0.3749688981053061,0.3076923076923077,0.2640035864646367,0.4698859394058132,0.20588235294117652
C19orf81,ENSG00000235034,6.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.7,3,0.5,47,6.7,0.0,0.0,0.3,8,0.5,39,13.4,False,0,0,,,,True,True,29,20,GBM:TCGA|GBM:validation|KIRC:validation|LIHC:TCGA|OV:TCGA|OV:validation|PRAD:TCGA|STAD:TCGA|TGCT:TCGA,lymphoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0019801980198019802,0.0019801980198019802,0.0,0.003663003663003663,0.31135531135531136,0.3076923076923077,0.021823274764451235,0.22770562770562774,0.20588235294117652
GAGE12F,ENSG00000236362,103.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,103.3,3,8.3,47,103.3,0.5,0.0,0.0,8,8.3,39,12.445783132530119,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Jamin2021_CT|Jamin2021_core|Loriot2025_S2|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|HNSC:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.04464766003227542,0.35233996772458315,0.3076923076923077,0.013513513513513513,0.21939586645469003,0.20588235294117652
CCDC200,ENSG00000236383,43.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,43.9,3,4.4,47,43.9,1.1,0.7,1.1,8,4.4,39,9.977272727272727,False,0,0,,,,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.12583436058364197,0.12583436058364197,0.0,0.06258942841303465,0.3702817361053424,0.3076923076923077,0.2520667270827117,0.45794908002388823,0.20588235294117652
UBE2L5,ENSG00000236444,44.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,44.7,3,0.8,47,44.7,0.2,0.1,0.8,8,0.6,39,55.875,False,0,0,,,,True,True,29,20,BLCA:TCGA|CESC:TCGA|GBM:validation|SKCM:TCGA|TGCT:TCGA,colorectal cancer|prostate cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0326092701231436,0.0326092701231436,0.0,0.0196942137714216,0.3273865214637293,0.3076923076923077,0.0761333189402243,0.2820156718814008,0.20588235294117652
GAGE12B,ENSG00000236737,137.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,137.7,3,3.1,47,137.7,0.9,0.0,3.1,8,3.0,39,44.41935483870967,False,1,0,Cancer-germline,10.1002/1878-0261.12900,Jamin2021_CT|Jamin2021_core,True,False,30,0,BRCA:TCGA|CESC:TCGA|GBM:TCGA|HNSC:TCGA|KIRC:TCGA|KIRP:TCGA|LUAD:TCGA|OV:TCGA|PAAD:TCGA|PRAD:TCGA|READ:TCGA|STAD:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04446993136313525,0.04446993136313525,0.0,0.040710514975220866,0.3484028226675286,0.3076923076923077,0.1253769969626358,0.33125934990381234,0.20588235294117652
LRRC37A2,ENSG00000238083,6.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.7,3,0.7,47,6.7,0.2,0.1,0.4,8,0.7,39,9.571428571428573,False,1,0,Cancer-germline,10.1038/s41388-018-0357-2,Bruggeman2018_GC,True,True,31,20,BRCA:validation|COAD:validation|GBM:validation|LIHC:validation|LUAD:validation|OV:validation|PAAD:validation|READ:validation|STAD:TCGA,liver cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03990261529707012,0.03990261529707012,0.0,0.03256745508759096,0.34025976277989867,0.3076923076923077,0.10733022542485457,0.3132125783660311,0.20588235294117652
PAGE2B,ENSG00000238269,55.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,55.0,3,4.0,47,55.0,0.3,0.3,0.3,8,4.0,39,13.75,False,4,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Loriot2025_S2|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|GBM:validation|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.03405018896612036,0.03405018896612036,0.0,0.016999922341011713,0.32469223003331943,0.3076923076923077,0.09406035141329258,0.2999427043544691,0.20588235294117652
MEIKIN,ENSG00000239642,7.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,7.3,3,0.6,47,7.3,0.0,0.3,0.0,8,0.6,39,12.166666666666666,False,0,0,,,,True,False,29,0,BRCA:TCGA|GBM:TCGA|GBM:validation|KIRC:validation|LUAD:TCGA|LUAD:validation|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.00788196466705494,0.00788196466705494,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.03205592361602592,0.23793827655720243,0.20588235294117652
SMKR1,ENSG00000240204,120.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,120.1,3,10.0,47,120.1,0.5,0.2,6.4,8,10.0,39,12.01,False,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04195071480254313,0.04195071480254313,0.0,0.06622573216910238,0.3739180398614101,0.3076923076923077,0.2036245969286263,0.40950694986980285,0.20588235294117652
L1TD1,ENSG00000240563,11.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11.2,3,5.2,47,5.6,0.1,11.2,0.3,8,5.2,39,2.1538461538461537,False,4,0,Cancer-germline,10.1002/1878-0261.12900|10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Jamin2021_CT|Wang2016_CT,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:validation|LUAD:validation|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|READ:TCGA|READ:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.034029404434901545,0.034029404434901545,0.0,0.057084914468573916,0.3647772221608816,0.3076923076923077,0.0584133909318203,0.2642957438729968,0.20588235294117652
KRBOX1,ENSG00000240747,192.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,192.1,3,8.2,47,192.1,10.0,0.1,8.2,8,5.3,39,23.426829268292686,False,1,0,Cancer-germline,10.1002/cam4.2223,Chang2019_TGCT,True,False,30,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.2336132584329992,0.2336132584329992,0.0,0.18643653438715352,0.49412884207946123,0.3076923076923077,0.4414767526984698,0.6473591056396464,0.20588235294117652
TCP10L,ENSG00000242220,198.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,198.0,3,18.4,47,198.0,1.4,0.5,2.0,8,18.4,39,10.760869565217392,False,2,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,liver cancer|thyroid cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.07028681430636331,0.07028681430636331,0.0,0.05394711691040799,0.3616394246027157,0.3076923076923077,0.30542498832280474,0.5113073412639813,0.20588235294117652
GTF2A1L,ENSG00000242441,58.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,58.2,3,8.4,47,58.2,2.0,0.2,4.1,8,8.4,39,6.928571428571429,False,1,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BLCA:TCGA|BRCA:validation|CESC:TCGA|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|SKCM:TCGA|STAD:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.07212671816632213,0.07212671816632213,0.0,0.11424401543615548,0.4219363231284632,0.3076923076923077,0.16933652891314183,0.37521888185431834,0.20588235294117652
CCDC169,ENSG00000242715,57.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,57.5,3,2.8,47,57.5,0.3,0.5,2.4,8,2.8,39,20.53571428571429,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1371/journal.pgen.1011734,Chang2019_TGCT|Loriot2025_S2|Wang2016_CT,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.038283683278995936,0.038283683278995936,0.0,0.06957285230670007,0.3772651599990078,0.3076923076923077,0.1729240353281274,0.3788063882693039,0.20588235294117652
ZNF709,ENSG00000242852,14.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,14.9,3,3.0,47,14.9,2.5,1.0,2.0,8,3.0,39,4.966666666666667,False,1,0,Cancer-germline,10.1038/s41388-018-0357-2,Bruggeman2018_GC,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1311552455615752,0.1311552455615752,0.0,0.09162749093586223,0.3993197986281699,0.3076923076923077,0.2676374136813643,0.4735197666225408,0.20588235294117652
ERVW-1,ENSG00000242950,52.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,52.8,3,6.7,47,5.8,0.3,52.8,3.4,8,6.7,39,7.880597014925373,False,2,0,Cancer-germline|Cancer-placental|Cancer-reproductive,10.1002/1878-0261.12900|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734,Gong2021_placenta_PC|Gong2021_reproductive_PC|Jamin2021_CT|Loriot2025_S2,True,False,29,0,BRCA:TCGA|CESC:TCGA|COAD:validation|GBM:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline|Cancer-placental,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06316430718385618,0.06316430718385618,0.0,0.04902097637668194,0.35671328406898967,0.3076923076923077,0.14809401409851183,0.3539763670396884,0.20588235294117652
CFAP57,ENSG00000243710,22.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,15.3,3,22.7,47,15.3,0.2,0.2,22.7,8,13.6,39,0.6740088105726872,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,True,29,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|GBM:TCGA|GBM:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:validation|PRAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,colorectal cancer|endometrial cancer|melanoma,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.04111644921855799,0.04111644921855799,0.0,0.007525525769840948,0.31521783346214866,0.3076923076923077,0.1797468238861314,0.3856291768273079,0.20588235294117652
TMEM225B,ENSG00000244219,133.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,133.2,3,3.8,47,133.2,1.5,1.3,3.4,8,3.8,39,35.05263157894737,False,0,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_testis_biased,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.19373449573393772,0.19373449573393772,0.0,0.10316948501811661,0.41086179271042433,0.3076923076923077,0.308024696474492,0.5139070494156686,0.20588235294117652
ERVFRD-1,ENSG00000244476,35.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,35.8,3,7.2,47,0.1,0.0,35.8,1.0,8,7.2,39,4.972222222222221,False,0,0,Cancer-placental|Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_placenta_PC|Gong2021_reproductive_PC,True,False,29,0,BLCA:TCGA|COAD:validation|KICH:TCGA|KIRP:TCGA|LUAD:validation|LUSC:validation|READ:validation|TGCT:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.02304135993456382,0.02304135993456382,0.0,0.06638052807407648,0.37407283576638417,0.3076923076923077,0.06842569195510372,0.27430804489628025,0.20588235294117652
PGAM5,ENSG00000247077,16.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,16.1,3,32.0,47,16.1,7.0,10.3,11.9,8,32.0,39,0.503125,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.5646652789086278,0.5646652789086278,0.0,0.4963768962573066,0.8040692039496142,0.3076923076923077,0.6907910946221989,0.8966734475633754,0.20588235294117652
MISFA,ENSG00000247595,473.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,473.9,3,13.8,47,473.9,1.6,1.2,3.6,8,13.8,39,34.34057971014492,False,0,0,,,,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.18732016906608154,0.18732016906608154,0.0,0.11013793953298945,0.41783024722529716,0.3076923076923077,0.28622317222307886,0.4921055251642554,0.20588235294117652
USP51,ENSG00000247746,48.3,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,4.9,3,48.3,47,2.2,4.9,2.2,48.3,8,5.4,39,0.10144927536231885,False,1,0,Cancer-germline,10.1038/s41388-018-0357-2,Bruggeman2018_GC,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,False,True,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.17951104256038833,0.17951104256038833,0.0,0.11260016260062526,0.420292470292933,0.3076923076923077,0.3234324269063194,0.529314779847496,0.20588235294117652
INSL3,ENSG00000248099,397.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,True,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,397.1,3,5.1,47,397.1,124.5,0.3,0.8,8,5.1,39,77.86274509803923,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|HNSC:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0964162715271826,0.0964162715271826,0.0,0.06304385659589279,0.3707361642882005,0.3076923076923077,0.16148939003015061,0.36737174297132713,0.20588235294117652
PCDHAC1,ENSG00000248383,0.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; Insufficient reproductive RNA/protein or reviewed affirmative support for admission; The pinned restriction/selectivity screen does not pass,False,False,False,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.7,3,28.8,47,0.7,0.0,0.0,0.4,8,28.8,39,0.024305555555555552,False,2,0,Cancer-germline,10.1038/s41388-018-0357-2|10.18632/oncotarget.21715,Bruggeman2018_GC|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:validation|CESC:TCGA|COAD:validation|GBM:TCGA|GBM:validation|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|READ:validation|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.028127637787648582,0.028127637787648582,0.0,0.08381075067762463,0.3915030583699323,0.3076923076923077,0.09402878366763359,0.2999111366088101,0.20588235294117652
POU5F2,ENSG00000248483,1.9,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,1.9,3,1.0,47,1.9,0.0,0.1,0.2,8,1.0,39,1.9,False,2,0,Cancer-germline,10.1038/ncomms10499|10.18632/oncotarget.21715,Wang2016_CT|daSilva2017_CT|daSilva2017_testis_biased,True,True,31,20,BLCA:TCGA|BRCA:validation|COAD:validation|GBM:validation|PAAD:validation|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.015574272359362634,0.015574272359362634,0.0,0.010006915348004719,0.31769922304031245,0.3076923076923077,0.03122612681436211,0.23710847975553861,0.20588235294117652
ATP6V1E2,ENSG00000250565,27.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,27.6,3,6.3,47,27.6,1.6,1.0,6.3,8,4.2,39,4.380952380952381,False,1,0,Cancer-germline,10.1038/s41388-018-0357-2,Bruggeman2018_GC,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.15218122262285824,0.15218122262285824,0.0,0.13656749663299295,0.44425980432530066,0.3076923076923077,0.38641686915647866,0.5922992220976552,0.20588235294117652
CENPS-CORT,ENSG00000251503,35.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,35.2,3,8.3,47,35.2,0.5,0.3,0.9,8,8.3,39,4.240963855421687,False,0,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_testis_biased,True,False,29,0,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0878534542468613,0.0878534542468613,0.0,0.08788490283021176,0.3955772105225195,0.3076923076923077,0.294710849632446,0.5005932025736225,0.20588235294117652
NACA2,ENSG00000253506,62.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,62.4,3,1.3,47,62.4,1.9,0.1,1.1,8,1.3,39,48.0,False,2,0,Cancer-germline|Cancer-reproductive,10.1038/s41388-018-0357-2|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Bruggeman2018_GC|Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,True,False,31,0,BRCA:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.06732623727113626,0.06732623727113626,0.0,0.051998394847662256,0.35969070253997,0.3076923076923077,0.19567710093130494,0.4015594538724815,0.20588235294117652
EIF5AL1,ENSG00000253626,10.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.2,3,1.5,47,10.2,0.3,0.0,0.6,8,1.5,39,6.8,False,0,0,,,,True,False,31,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRP:TCGA|LIHC:TCGA|LUAD:TCGA|LUSC:TCGA|OV:TCGA|PAAD:TCGA|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.050313549378969945,0.050313549378969945,0.0,0.047068899239265334,0.35476120693157304,0.3076923076923077,0.1751779005846825,0.38106025352585904,0.20588235294117652
EID3,ENSG00000255150,59.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,59.4,3,6.4,47,59.4,3.9,1.6,5.3,8,6.4,39,9.28125,False,2,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499,Chang2019_TGCT|Wang2016_CT,True,False,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.20625334659864905,0.20625334659864905,0.0,0.1688821983829325,0.4765745060752402,0.3076923076923077,0.41941756111976874,0.6252999140609452,0.20588235294117652
CLEC12B,ENSG00000256660,13.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.0,3,5.4,47,13.0,0.0,0.0,0.2,8,5.4,39,2.4074074074074074,False,3,0,Cancer-germline,10.1002/cam4.2223|10.1038/ncomms10499|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Chang2019_TGCT|Wang2016_CT,True,False,31,0,BRCA:validation|GBM:validation|LUAD:validation|SKCM:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.09589932237370895,0.09589932237370895,0.0,0.007566204287515765,0.31525851197982346,0.3076923076923077,0.0772170757464875,0.283099428687664,0.20588235294117652
SPESP1,ENSG00000258484,70.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,70.8,3,6.1,47,70.8,4.1,12.4,6.1,8,4.5,39,11.60655737704918,False,0,0,,,,True,True,31,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,liver cancer|skin cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.12269819942504252,0.12269819942504252,0.0,0.1623370223601891,0.4700293300524968,0.3076923076923077,0.34503047200657855,0.5509128249477551,0.20588235294117652
TBC1D3G,ENSG00000260287,25.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,25.4,3,2.7,47,25.4,0.9,0.0,1.5,8,2.7,39,9.407407407407407,False,0,0,Cancer-germline,10.18632/oncotarget.21715,daSilva2017_testis_biased,True,False,28,20,BRCA:validation|LIHC:validation,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.056459780361277224,0.056459780361277224,0.0,0.04228303747534517,0.3499753451676529,0.3076923076923077,0.1871930758674311,0.39307542880860763,0.20588235294117652
C16orf95,ENSG00000260456,98.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,98.6,3,6.8,47,98.6,1.4,0.4,2.1,8,6.8,39,14.5,False,1,0,Cancer-germline,10.1002/cam4.2223,Chang2019_TGCT,True,False,30,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|GBM:validation|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|PAAD:TCGA|PAAD:validation|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.1367136058580659,0.1367136058580659,0.0,0.14170302171249133,0.44939532940479904,0.3076923076923077,0.42639843814566497,0.6322807910868415,0.20588235294117652
C19orf84,ENSG00000262874,21.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,False,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,21.4,3,0.6,47,21.4,0.0,0.1,0.1,8,0.6,39,35.666666666666664,False,1,0,Cancer-germline|Cancer-reproductive,10.1002/cam4.2223|10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Chang2019_TGCT|Gong2021_reproductive_PC|daSilva2017_testis_biased,True,False,29,20,BLCA:TCGA|CESC:TCGA|GBM:TCGA|HNSC:TCGA|LUAD:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|OV:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.009672505712109673,0.009672505712109673,0.0,0.0024813895781637717,0.3101736972704715,0.3076923076923077,0.024810973340385102,0.2306933262815616,0.20588235294117652
CT45A1,ENSG00000268940,11.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,False,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,11.6,3,0.8,47,11.6,0.0,0.0,0.0,8,0.8,39,14.499999999999998,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Gong2021_reproductive_PC|Jamin2021_CT|Jamin2021_core|Loriot2025_S1|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,28,20,BLCA:TCGA|HNSC:TCGA|LIHC:TCGA|LUAD:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,ovarian cancer|stomach cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.04649051928463693,0.25237287222581345,0.20588235294117652
CT45A3,ENSG00000269096,9.2,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,True,True,False,False,False,False,True,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,Accepted normal IHC is positive in a non-permitted compartment; Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,Protein,Accepted normal IHC is positive in a non-permitted compartment,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.2,3,2.3,47,9.2,0.0,0.0,0.0,8,2.3,39,4.0,False,3,0,Cancer-germline|Cancer-reproductive,10.1002/1878-0261.12900|10.1038/s41467-021-22695-y|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Gong2021_reproductive_PC|Jamin2021_CT|Jamin2021_core|Loriot2025_S1|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,True,28,20,BLCA:TCGA|BRCA:validation|GBM:TCGA|HNSC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,ovarian cancer|stomach cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal IHC positive|Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.06531982083479156,0.27120217377596806,0.20588235294117652
NXF2,ENSG00000269405,14.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,10.0,3,14.8,47,10.0,0.0,0.0,14.8,8,3.2,39,0.6756756756756757,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1371/journal.pgen.1011734,Jamin2021_CT|Jamin2021_core|Loriot2025_S1,True,True,28,20,COAD:TCGA|COAD:validation|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,False,True,Publication consensus,Cancer-germline|Cancer-reproductive,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.05946137196137196,0.2653437249025485,0.20588235294117652
NXF2B,ENSG00000269437,14.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,6.9,3,14.8,47,6.9,0.0,0.0,14.8,8,2.4,39,0.46621621621621623,False,1,0,Cancer-germline,10.1002/1878-0261.12900,Jamin2021_CT|Jamin2021_core,True,True,28,20,COAD:TCGA|COAD:validation|HNSC:TCGA|LIHC:TCGA|LIHC:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|READ:TCGA|READ:validation|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|stomach cancer|testis cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,False,True,Expression-supported,Cancer-reproductive,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.001261034047919294,0.308953341740227,0.3076923076923077,0.0503317015465353,0.25621405448771184,0.20588235294117652
HEATR9,ENSG00000270379,9.8,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,True,True,False,False,False,True,False,True,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Uncertain normal antibody evidence requires review; Normal-cell RNA crosses a source-specific review trigger,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,9.8,3,0.4,47,9.8,0.0,0.0,0.1,8,0.4,39,24.5,False,1,0,Cancer-germline|Cancer-reproductive,10.1038/s41467-021-22695-y|10.18632/oncotarget.21715,Gong2021_reproductive_PC|daSilva2017_CT|daSilva2017_testis_biased,False,True,26,20,,breast cancer|carcinoid|cervical cancer|colorectal cancer|endometrial cancer|glioma|head and neck cancer|liver cancer|lung cancer|lymphoma|melanoma|ovarian cancer|pancreatic cancer|prostate cancer|renal cancer|skin cancer|stomach cancer|thyroid cancer|urothelial cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Antibody concern|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.007692307692307693,0.007692307692307693,0.0,0.0037831021437578823,0.3114754098360656,0.3076923076923077,0.008148714031066972,0.2140310669722435,0.20588235294117652
ZNF595,ENSG00000272602,58.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,58.5,3,10.5,47,8.5,13.4,58.5,10.4,8,10.5,39,5.571428571428571,False,0,0,,,,True,False,28,0,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:TCGA|LIHC:validation|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-placental,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.468672545516409,0.468672545516409,0.0,0.34923705729737037,0.6569293649896781,0.3076923076923077,0.5998673612800371,0.8057497142212137,0.20588235294117652
ZNF280B,ENSG00000275004,13.0,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,13.0,3,3.2,47,13.0,1.6,0.2,1.0,8,3.2,39,4.0625,False,2,0,Cancer-germline,10.1002/1878-0261.12900|10.1038/s41388-018-0357-2,Bruggeman2018_GC|Jamin2021_CT,True,True,28,20,BLCA:TCGA|BRCA:TCGA|BRCA:validation|CESC:TCGA|COAD:TCGA|COAD:validation|GBM:TCGA|HNSC:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PAAD:TCGA|PRAD:TCGA|READ:TCGA|READ:validation|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA|UCEC:TCGA,liver cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,True,True,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.071066790130197,0.071066790130197,0.0,0.046110617385038105,0.3538029250773458,0.3076923076923077,0.19490755994263712,0.4007899128838136,0.20588235294117652
GAGE2E,ENSG00000275113,25.4,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,25.4,3,14.9,47,25.4,0.3,0.0,0.1,8,14.9,39,1.704697986577181,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Jamin2021_CT|Jamin2021_core|Loriot2025_S2|daSilva2017_CT|daSilva2017_testis_biased|daSilva2017_tumor_proteomics,True,False,28,20,BLCA:TCGA|BRCA:TCGA|CESC:TCGA|GBM:TCGA|HNSC:TCGA|LIHC:TCGA|LUAD:TCGA|LUSC:TCGA|LUSC:validation|OV:TCGA|READ:TCGA|SKCM:TCGA|STAD:TCGA|TGCT:TCGA|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.00788196466705494,0.00788196466705494,0.0,0.05976393465608307,0.3674562423483908,0.3076923076923077,0.024446142093200913,0.23032849503437744,0.20588235294117652
CT45A6,ENSG00000278289,0.1,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,True,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,0.1,3,3.9,47,0.1,0.0,0.0,0.0,8,3.9,39,0.025641025641025644,False,3,0,Cancer-germline,10.1002/1878-0261.12900|10.1371/journal.pgen.1011734|10.18632/oncotarget.21715,Jamin2021_CT|Jamin2021_core|Loriot2025_S1|daSilva2017_CT|daSilva2017_testis_biased,True,True,28,20,LUSC:TCGA|LUSC:validation|OV:TCGA|STAD:TCGA|TGCT:TCGA,ovarian cancer|stomach cancer|testis cancer,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,True,False,False,False,Publication consensus,Cancer-germline,At least two distinct class-specific cancer/reproductive publications,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.0,0.0,0.0,0.0,0.3076923076923077,0.3076923076923077,0.046413534745414105,0.2522958876865906,0.20588235294117652
TMEM191B,ENSG00000278558,90.5,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,False,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; No source-backed cancer/reproductive candidate nomination,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,90.5,3,2.9,47,90.5,0.2,0.0,0.7,8,2.9,39,31.20689655172414,False,0,0,,,,True,False,27,0,BLCA:TCGA|GBM:TCGA|KICH:TCGA|KIRC:TCGA|KIRC:validation|KIRP:TCGA|LIHC:validation|LUAD:TCGA|OV:TCGA|PAAD:TCGA|STAD:TCGA|TGCT:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,,,,Not assessed in prior cell-RNA audit,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.055242936155689044,0.055242936155689044,0.0,0.027054256720524857,0.33474656441283257,0.3076923076923077,0.1504946177721204,0.3563769707132969,0.20588235294117652
TEX54,ENSG00000283268,74.7,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,True,False,False,False,True,False,False,True,False,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM; Normal-cell RNA crosses a source-specific review trigger; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,High RNA,Observed non-permitted or unsited normal RNA exceeds 30 TPM or nTPM,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,74.7,3,1.8,47,74.7,0.3,0.1,0.5,8,1.8,39,41.5,False,0,0,Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_reproductive_PC,True,False,26,0,BRCA:TCGA|COAD:validation|GBM:TCGA|KIRC:TCGA|LUAD:TCGA|LUAD:validation|LUSC:TCGA|LUSC:validation|OV:TCGA|PRAD:TCGA|READ:validation|STAD:TCGA|THCA:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,True,True,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,High normal RNA|Cell RNA concern|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.035784382337597016,0.035784382337597016,0.0,0.03233510039026046,0.34002740808256815,0.3076923076923077,0.10464823312979406,0.31053058607097056,0.20588235294117652
HSFX4,ENSG00000283463,14.6,9606,openvax:reference:v1:sha256:0fefb51755788901693be9987fadc31e61f945cd53c08a170e0e1d4ad4a09b61,True,False,False,False,False,True,False,False,False,False,False,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,Normal RNA exceeds its applicable local category/IHC ceiling; The declared measurement panel or reference coverage is incomplete; The pinned restriction/selectivity screen does not pass,False,False,True,False,,,,,,False,True,oncoref.cta-research-selection.2026-10-26.1,Unsafe,RNA,Normal RNA exceeds its applicable local category/IHC ceiling,oncoref.target-sets.2026-10-25.2,False,,,Not selected,Unchanged,14.6,3,2.7,47,14.6,0.4,0.1,0.2,8,2.7,39,5.4074074074074066,False,0,0,Cancer-reproductive,10.1038/s41467-021-22695-y,Gong2021_reproductive_PC,True,False,26,0,COAD:validation|PRAD:TCGA|READ:validation|UCEC:TCGA,,False,1,3,0.05,2,,No gene-specific review,,,,RNA/protein mapping; paralog specificity unverified,True,False,False,True,True,False,Expression-supported,Cancer-germline,Measured reproductive enrichment plus published or measured tumor support,oncoref.cta-membership.2026-10-26.2,Added,False,False,False,Prior tissue/IHC audit; see linked rows,Retained expression findings; not clinical safety clearance,Normal RNA failure|Expression forbidden,Not imported; oncofetal admission uses cited gene-specific evidence,Individual donors unassessed; consensus RNA is not a donor uncertainty estimate,0.011842360706658901,0.011842360706658901,0.0,0.005044136191677176,0.31273644388398486,0.3076923076923077,0.06380879237575107,0.2696911453169276,0.20588235294117652