# 🧬 ARIA Clinical Research MCP Server A standalone MCP server that gives any Claude agent real-time access to biomedical literature and clinical trials — no API keys required. [](https://glama.ai/mcp/servers/pkotecha-eng/aria-mcp-server) ## Tools | Tool | Description | |------|-------------| | `search_pubmed` | Search 35M+ peer-reviewed papers via NCBI E-utilities | | `search_clinical_trials` | Search 400K+ trials via ClinicalTrials.gov v2 API | | `search_isrctn` | Search UK/European trials via ISRCTN registry | ## Prompts | Prompt | Description | |--------|-------------| | `clinical-research-brief` | Comprehensive evidence + trial brief for a condition | | `adverse-event-analysis` | Structured AE and safety profile for a drug | | `trial-eligibility-checker` | Patient eligibility assessment across recruiting trials | ## Resources | Resource | Description | |----------|-------------| | `info://aria` | Overview of ARIA capabilities and data sources | | `reference://trial-phases` | Phase I–IV definitions and FDA special designations | | `reference://high-impact-journals` | Curated high-impact journals by specialty | | `reference://fda-databases` | FDA databases for drug, safety, and regulatory research | ## Example queries Once connected, ask Claude: - "Search PubMed for ketogenic diet pediatric epilepsy outcomes" - "Find recruiting trials for lung cancer immunotherapy" - "What does the literature say about veliparib in ovarian cancer, and are there active trials?" - "Find UK and European trials for pediatric epilepsy via ISRCTN" ## Quickstart ```bash pip install aria-mcp-server aria-mcp-server ``` ## Connect to Claude Desktop Add to `~/Library/Application Support/Claude/claude_desktop_config.json`: ```json { "mcpServers": { "aria-clinical-research": { "command": "aria-mcp-server" } } } ``` Restart Claude Desktop. The server will appear under Settings → Developer → Local MCP Servers. ## Data sources - **PubMed** — NCBI E-utilities (public API, no key required) - **ClinicalTrials.gov** — v2 REST API (public API, no key required) - **ISRCTN** — UK/European clinical trials registry (public API, no key required) ## Tech stack - [FastMCP](https://gofastmcp.com) — MCP server framework - Python 3.12+ ## Use cases - Life sciences researchers needing real-time literature access - Clinical trial coordinators checking eligibility and recruiting status - Drug discovery teams cross-referencing published evidence with active trials - Any Claude agent needing grounded biomedical knowledge ## Project Structure ``` aria-mcp-server/ ← root, where mcp-publisher runs ├── aria_mcp_server/ ← Python package │ ├── __init__.py │ ├── server.py │ └── tools.py ├── server.json ← MCP registry metadata ├── pyproject.toml ├── README.md ├── LICENSE └── glama.json ``` ## Built by Pooja Kotecha · [dinq.me/pkotecha-eng](https://dinq.me/pkotecha-eng)