diff -u -r -N a/src/Illuminate/Database/Query/Builder.php b/src/Illuminate/Database/Query/Builder.php
--- a/src/Illuminate/Database/Query/Builder.php	2021-01-20 14:42:53.721641186 -0800
+++ b/src/Illuminate/Database/Query/Builder.php	2021-02-04 15:20:57.506670288 -0800
@@ -398,7 +398,7 @@
 
 		if ( ! $value instanceof Expression)
 		{
-			$this->bindings[] = is_array($value) ? head($value) : $value;
+			$this->bindings[] = $this->scalarValue($value);
 		}
 
 		return $this;
@@ -477,7 +477,7 @@
 
 		$this->wheres[] = compact('column', 'type', 'boolean', 'not');
 
-		$this->bindings = array_merge($this->bindings, array_slice($values, 0, 2));
+		$this->bindings = array_merge($this->bindings, array_slice(self::flatten($values), 0, 2));
 
 		return $this;
 	}
@@ -846,7 +846,7 @@
 	{
 		$this->wheres[] = compact('column', 'type', 'boolean', 'operator', 'value');
 
-		$value = is_array($value) ? head($value) : $value;
+		$value = $this->scalarValue($value);
 		$this->bindings[] = $value;
 
 		return $this;
@@ -942,7 +942,7 @@
 
 		$this->havings[] = compact('type', 'column', 'operator', 'value');
 
-		$this->bindings[] = is_array($value) ? head($value) : $value;
+		$this->bindings[] = $this->scalarValue($value);
 
 		return $this;
 	}
@@ -1994,4 +1994,40 @@
 		throw new \BadMethodCallException("Call to undefined method {$className}::{$method}()");
 	}
 
+	/**
+	 * Returns scalar type value from an unknown type of input.
+	 *
+	 * @param  mixed  $value
+	 * @return mixed
+	 */
+	protected function scalarValue($value)
+	{
+		return is_array($value) ? head(self::flatten($value)) : $value;
+	}
+
+	/**
+	 * Flatten a multi-dimensional array into a single level. (Ported from Arr::flatten)
+	 *
+	 * @param  array  $array
+	 * @param  int  $depth
+	 * @return array
+	 */
+	public static function flatten($array, $depth = INF)
+	{
+		$result = [];
+
+		foreach ($array as $item) {
+			$item = $item instanceof Collection ? $item->all() : $item;
+
+			if (! is_array($item)) {
+				$result[] = $item;
+			} elseif ($depth === 1) {
+				$result = array_merge($result, array_values($item));
+			} else {
+				$result = array_merge($result, static::flatten($item, $depth - 1));
+			}
+		}
+
+		return $result;
+	}
 }