{
  "benchmark": "mfass-v2",
  "method": "baseline-kmer-position",
  "family": "trivial baseline",
  "description": "exon-boundary distances, allele identity, phyloP and phastCons conservation, and 3-mer composition of a 21bp assay-oriented window, HistGradientBoosting",
  "split": "benchmarks/mfass/splits/split-v2.tsv",
  "metrics": {
    "n": 8324,
    "positives": 315,
    "prevalence": 0.037842383469485825,
    "capacity": 100,
    "precision_at_capacity": 0.61,
    "recall_at_capacity": 0.19365079365079366,
    "average_precision_sklearn": 0.2864167459589237,
    "auroc": 0.7779498064677238
  },
  "coverage": {
    "scored": 8324,
    "unscored": 0,
    "denominator": 8324
  },
  "timing_seconds": {
    "load_and_validate_cohort_and_split": 0.273,
    "featurise_train_and_test": 0.469,
    "fit": 0.638,
    "predict_test": 0.012,
    "end_to_end": 1.399,
    "per_variant_total": 5e-05
  },
  "independent_groups": 463,
  "config": {
    "trained_on_variants": 19409,
    "trained_on_positives": 735,
    "seed": 20260914,
    "kmer_k": 3,
    "window": 21,
    "features": "exon-boundary distances, allele identity, phyloP, phastCons, 3-mers",
    "sequence_orientation": "validated assay-oriented original_seq at rel_position - 1",
    "cohort_sha256": "389702ff4c647d7ce10a90092a6fa811ae777d15997baf39ce9aae0346247bd0",
    "split_sha256": "999ebcb7e63a5c5eaa8780fa468e59ac1f934260ad50102814174c396317f052"
  },
  "contamination": null,
  "pretrained": false,
  "notes": "Corrected from mfass-v1: the old baseline centred windows using raw sequence, which was reverse-complemented for 7,770 variants; v1 artifacts are preserved.",
  "environment": {
    "python": "3.11.13",
    "platform": "macOS-26.6.2-arm64-arm-64bit",
    "machine": "arm64",
    "processor": "arm"
  },
  "created_utc": "2026-09-15T23:39:17.174385+00:00",
  "git_revision": "edf5b5c"
}