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e=new DataView(t),n=U.Utils.getIntAt(e,0,this.littleEndian),r,a,s,l;if(n!==b.MAGIC_COOKIE&&(this.littleEndian=!0,n=U.Utils.getIntAt(e,0,this.littleEndian)),n!==b.MAGIC_COOKIE)throw new Error("This does not appear to be a NIFTI 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o=this.quatern_a,f=this.quatern_b,u=this.quatern_c,h=this.quatern_d;for(this.qfac=this.pixDims[0]===0?1:this.pixDims[0],this.quatern_R=[[o*o+f*f-u*u-h*h,2*f*u-2*o*h,2*f*h+2*o*u],[2*f*u+2*o*h,o*o+u*u-f*f-h*h,2*u*h-2*o*f],[2*f*h-2*o*u,2*u*h+2*o*f,o*o+h*h-u*u-f*f]],a=0;a<3;a+=1)for(s=0;s<3;s+=1)this.affine[a][s]=this.quatern_R[a][s]*this.pixDims[s+1],s===2&&(this.affine[a][s]*=this.qfac);this.affine[0][3]=this.qoffset_x,this.affine[1][3]=this.qoffset_y,this.affine[2][3]=this.qoffset_z}else if(this.sform_code>0)for(a=0;a<3;a+=1)for(s=0;s<4;s+=1)l=280+(a*4+s)*4,this.affine[a][s]=U.Utils.getFloatAt(e,l,this.littleEndian);if(this.affine[3][0]=0,this.affine[3][1]=0,this.affine[3][2]=0,this.affine[3][3]=1,this.intent_name=U.Utils.getStringAt(e,328,344),this.magic=U.Utils.getStringAt(e,344,348),this.isHDR=this.magic===String.fromCharCode.apply(null,b.MAGIC_NUMBER2),e.byteLength>b.MAGIC_COOKIE){this.extensionFlag[0]=U.Utils.getByteAt(e,348),this.extensionFlag[1]=U.Utils.getByteAt(e,348+1),this.extensionFlag[2]=U.Utils.getByteAt(e,348+2),this.extensionFlag[3]=U.Utils.getByteAt(e,348+3);let o=!0;!this.isHDR&&this.vox_offset<=352&&(o=!1),e.byteLength<=352+16&&(o=!1),o&&this.extensionFlag[0]&&(this.extensions=U.Utils.getExtensionsAt(e,this.getExtensionLocation(),this.littleEndian,this.vox_offset),this.extensionSize=this.extensions[0].esize,this.extensionCode=this.extensions[0].ecode)}}toFormattedString(){var t=U.Utils.formatNumber,e="";return e+="Dim Info = "+this.dim_info+`
`,e+="Image Dimensions (1-8): "+this.dims[0]+", "+this.dims[1]+", "+this.dims[2]+", "+this.dims[3]+", "+this.dims[4]+", "+this.dims[5]+", "+this.dims[6]+", "+this.dims[7]+`
`,e+="Intent Parameters (1-3): "+this.intent_p1+", "+this.intent_p2+", "+this.intent_p3+`
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`,e+="Slice Start = "+this.slice_start+`
`,e+="Voxel Dimensions (1-8): "+t(this.pixDims[0])+", "+t(this.pixDims[1])+", "+t(this.pixDims[2])+", "+t(this.pixDims[3])+", "+t(this.pixDims[4])+", "+t(this.pixDims[5])+", "+t(this.pixDims[6])+", "+t(this.pixDims[7])+`
`,e+="Image Offset = "+this.vox_offset+`
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`,e+="Slice End = "+this.slice_end+`
`,e+="Slice Code = "+this.slice_code+`
`,e+="Units Code = "+this.xyzt_units+" ("+this.getUnitsCodeString(b.SPATIAL_UNITS_MASK&this.xyzt_units)+", "+this.getUnitsCodeString(b.TEMPORAL_UNITS_MASK&this.xyzt_units)+`)
`,e+="Display Range:  Max = "+t(this.cal_max)+"  Min = "+t(this.cal_min)+`
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`,e+='Description: "'+this.description+`"
`,e+='Auxiliary File: "'+this.aux_file+`"
`,e+="Q-Form Code = "+this.qform_code+" ("+this.getTransformCodeString(this.qform_code)+`)
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`,e+='Intent Name: "'+this.intent_name+`"
`,this.extensionFlag[0]&&(e+="Extension: Size = "+this.extensionSize+"  Code = "+this.extensionCode+`
`),e}getDatatypeCodeString=function(t){return t===b.TYPE_UINT8?"1-Byte Unsigned Integer":t===b.TYPE_INT16?"2-Byte Signed Integer":t===b.TYPE_INT32?"4-Byte Signed Integer":t===b.TYPE_FLOAT32?"4-Byte Float":t===b.TYPE_FLOAT64?"8-Byte Float":t===b.TYPE_RGB24?"RGB":t===b.TYPE_INT8?"1-Byte Signed Integer":t===b.TYPE_UINT16?"2-Byte Unsigned Integer":t===b.TYPE_UINT32?"4-Byte Unsigned Integer":t===b.TYPE_INT64?"8-Byte Signed Integer":t===b.TYPE_UINT64?"8-Byte Unsigned Integer":"Unknown"};getTransformCodeString=function(t){return t===b.XFORM_SCANNER_ANAT?"Scanner":t===b.XFORM_ALIGNED_ANAT?"Aligned":t===b.XFORM_TALAIRACH?"Talairach":t===b.XFORM_MNI_152?"MNI":"Unknown"};getUnitsCodeString=function(t){return t===b.UNITS_METER?"Meters":t===b.UNITS_MM?"Millimeters":t===b.UNITS_MICRON?"Microns":t===b.UNITS_SEC?"Seconds":t===b.UNITS_MSEC?"Milliseconds":t===b.UNITS_USEC?"Microseconds":t===b.UNITS_HZ?"Hz":t===b.UNITS_PPM?"PPM":t===b.UNITS_RADS?"Rads":"Unknown"};getQformMat(){return this.convertNiftiQFormToNiftiSForm(this.quatern_b,this.quatern_c,this.quatern_d,this.qoffset_x,this.qoffset_y,this.qoffset_z,this.pixDims[1],this.pixDims[2],this.pixDims[3],this.pixDims[0])}convertNiftiQFormToNiftiSForm(t,e,n,r,a,s,l,o,f,u){var h=[[0,0,0,0],[0,0,0,0],[0,0,0,0],[0,0,0,0]],v,m=t,g=e,p=n,c,y,A;return h[3][0]=h[3][1]=h[3][2]=0,h[3][3]=1,v=1-(m*m+g*g+p*p),v<1e-7?(v=1/Math.sqrt(m*m+g*g+p*p),m*=v,g*=v,p*=v,v=0):v=Math.sqrt(v),c=l>0?l:1,y=o>0?o:1,A=f>0?f:1,u<0&&(A=-A),h[0][0]=(v*v+m*m-g*g-p*p)*c,h[0][1]=2*(m*g-v*p)*y,h[0][2]=2*(m*p+v*g)*A,h[1][0]=2*(m*g+v*p)*c,h[1][1]=(v*v+g*g-m*m-p*p)*y,h[1][2]=2*(g*p-v*m)*A,h[2][0]=2*(m*p-v*g)*c,h[2][1]=2*(g*p+v*m)*y,h[2][2]=(v*v+p*p-g*g-m*m)*A,h[0][3]=r,h[1][3]=a,h[2][3]=s,h}convertNiftiSFormToNEMA(t){var e,n,r,a,s,l,o,f,u,h,v,m,g,p,c,y,A,T,x,R,O,M,d,Y,N,V,z,C,F,G,B,P,k,X;if(c=0,z=[[0,0,0],[0,0,0],[0,0,0]],C=[[0,0,0],[0,0,0],[0,0,0]],e=t[0][0],n=t[0][1],r=t[0][2],a=t[1][0],s=t[1][1],l=t[1][2],o=t[2][0],f=t[2][1],u=t[2][2],h=Math.sqrt(e*e+a*a+o*o),h===0||(e/=h,a/=h,o/=h,h=Math.sqrt(n*n+s*s+f*f),h===0))return null;if(n/=h,s/=h,f/=h,h=e*n+a*s+o*f,Math.abs(h)>1e-4){if(n-=h*e,s-=h*a,f-=h*o,h=Math.sqrt(n*n+s*s+f*f),h===0)return null;n/=h,s/=h,f/=h}if(h=Math.sqrt(r*r+l*l+u*u),h===0?(r=a*f-o*s,l=o*n-f*e,u=e*s-a*n):(r/=h,l/=h,u/=h),h=e*r+a*l+o*u,Math.abs(h)>1e-4){if(r-=h*e,l-=h*a,u-=h*o,h=Math.sqrt(r*r+l*l+u*u),h===0)return null;r/=h,l/=h,u/=h}if(h=n*r+s*l+f*u,Math.abs(h)>1e-4){if(r-=h*n,l-=h*s,u-=h*f,h=Math.sqrt(r*r+l*l+u*u),h===0)return null;r/=h,l/=h,u/=h}if(z[0][0]=e,z[0][1]=n,z[0][2]=r,z[1][0]=a,z[1][1]=s,z[1][2]=l,z[2][0]=o,z[2][1]=f,z[2][2]=u,v=this.nifti_mat33_determ(z),v===0)return null;for(V=-666,x=M=d=Y=1,R=2,O=3,g=1;g<=3;g+=1)for(p=1;p<=3;p+=1)if(g!==p){for(c=1;c<=3;c+=1)if(!(g===c||p===c))for(C[0][0]=C[0][1]=C[0][2]=C[1][0]=C[1][1]=C[1][2]=C[2][0]=C[2][1]=C[2][2]=0,y=-1;y<=1;y+=2)for(A=-1;A<=1;A+=2)for(T=-1;T<=1;T+=2)C[0][g-1]=y,C[1][p-1]=A,C[2][c-1]=T,m=this.nifti_mat33_determ(C),m*v>0&&(N=this.nifti_mat33_mul(C,z),h=N[0][0]+N[1][1]+N[2][2],h>V&&(V=h,x=g,R=p,O=c,M=y,d=A,Y=T))}switch(F=G=B=P=k=X="",x*M){case 1:F="X",P="+";break;case-1:F="X",P="-";break;case 2:F="Y",P="+";break;case-2:F="Y",P="-";break;case 3:F="Z",P="+";break;case-3:F="Z",P="-";break}switch(R*d){case 1:G="X",k="+";break;case-1:G="X",k="-";break;case 2:G="Y",k="+";break;case-2:G="Y",k="-";break;case 3:G="Z",k="+";break;case-3:G="Z",k="-";break}switch(O*Y){case 1:B="X",X="+";break;case-1:B="X",X="-";break;case 2:B="Y",X="+";break;case-2:B="Y",X="-";break;case 3:B="Z",X="+";break;case-3:B="Z",X="-";break}return F+G+B+P+k+X}nifti_mat33_mul=function(t,e){var n=[[0,0,0],[0,0,0],[0,0,0]],r,a;for(r=0;r<3;r+=1)for(a=0;a<3;a+=1)n[r][a]=t[r][0]*e[0][a]+t[r][1]*e[1][a]+t[r][2]*e[2][a];return n};nifti_mat33_determ=function(t){var e,n,r,a,s,l,o,f,u;return e=t[0][0],n=t[0][1],r=t[0][2],a=t[1][0],s=t[1][1],l=t[1][2],o=t[2][0],f=t[2][1],u=t[2][2],e*s*u-e*f*l-a*n*u+a*f*r+o*n*l-o*s*r};getExtensionLocation(){return b.MAGIC_COOKIE+4}getExtensionSize(t){return U.Utils.getIntAt(t,this.getExtensionLocation(),this.littleEndian)}getExtensionCode(t){return U.Utils.getIntAt(t,this.getExtensionLocation()+4,this.littleEndian)}addExtension(t,e=-1){e==-1?this.extensions.push(t):this.extensions.splice(e,0,t),this.vox_offset+=t.esize}removeExtension(t){let e=this.extensions[t];e&&(this.vox_offset-=e.esize),this.extensions.splice(t,1)}toArrayBuffer(t=!1){let r=352;if(t)for(let o of this.extensions)r+=o.esize;let a=new Uint8Array(r),s=new DataView(a.buffer);s.setInt32(0,348,this.littleEndian),s.setUint8(39,this.dim_info);for(let o=0;o<8;o++)s.setUint16(40+2*o,this.dims[o],this.littleEndian);s.setFloat32(56,this.intent_p1,this.littleEndian),s.setFloat32(60,this.intent_p2,this.littleEndian),s.setFloat32(64,this.intent_p3,this.littleEndian),s.setInt16(68,this.intent_code,this.littleEndian),s.setInt16(70,this.datatypeCode,this.littleEndian),s.setInt16(72,this.numBitsPerVoxel,this.littleEndian),s.setInt16(74,this.slice_start,this.littleEndian);for(let o=0;o<8;o++)s.setFloat32(76+4*o,this.pixDims[o],this.littleEndian);s.setFloat32(108,this.vox_offset,this.littleEndian),s.setFloat32(112,this.scl_slope,this.littleEndian),s.setFloat32(116,this.scl_inter,this.littleEndian),s.setInt16(120,this.slice_end,this.littleEndian),s.setUint8(122,this.slice_code),s.setUint8(123,this.xyzt_units),s.setFloat32(124,this.cal_max,this.littleEndian),s.setFloat32(128,this.cal_min,this.littleEndian),s.setFloat32(132,this.slice_duration,this.littleEndian),s.setFloat32(136,this.toffset,this.littleEndian),a.set(Buffer.from(this.description),148),a.set(Buffer.from(this.aux_file),228),s.setInt16(252,this.qform_code,this.littleEndian),s.setInt16(254,this.sform_code,this.littleEndian),s.setFloat32(256,this.quatern_b,this.littleEndian),s.setFloat32(260,this.quatern_c,this.littleEndian),s.setFloat32(264,this.quatern_d,this.littleEndian),s.setFloat32(268,this.qoffset_x,this.littleEndian),s.setFloat32(272,this.qoffset_y,this.littleEndian),s.setFloat32(276,this.qoffset_z,this.littleEndian);let l=this.affine.flat();for(let o=0;o<12;o++)s.setFloat32(280+4*o,l[o],this.littleEndian);if(a.set(Buffer.from(this.intent_name),328),a.set(Buffer.from(this.magic),344),t){a.set(Uint8Array.from([1,0,0,0]),348);let o=this.getExtensionLocation();for(let f of this.extensions)s.setInt32(o,f.esize,f.littleEndian),s.setInt32(o+4,f.ecode,f.littleEndian),a.set(new Uint8Array(f.edata),o+8),o+=f.esize}else a.set(new Uint8Array(4).fill(0),348);return a.buffer}},S=b;E(S,"TYPE_NONE",0),E(S,"TYPE_BINARY",1),E(S,"TYPE_UINT8",2),E(S,"TYPE_INT16",4),E(S,"TYPE_INT32",8),E(S,"TYPE_FLOAT32",16),E(S,"TYPE_COMPLEX64",32),E(S,"TYPE_FLOAT64",64),E(S,"TYPE_RGB24",128),E(S,"TYPE_INT8",256),E(S,"TYPE_UINT16",512),E(S,"TYPE_UINT32",768),E(S,"TYPE_INT64",1024),E(S,"TYPE_UINT64",1280),E(S,"TYPE_FLOAT128",1536),E(S,"TYPE_COMPLEX128",1792),E(S,"TYPE_COMPLEX256",2048),E(S,"XFORM_UNKNOWN",0),E(S,"XFORM_SCANNER_ANAT",1),E(S,"XFORM_ALIGNED_ANAT",2),E(S,"XFORM_TALAIRACH",3),E(S,"XFORM_MNI_152",4),E(S,"SPATIAL_UNITS_MASK",7),E(S,"TEMPORAL_UNITS_MASK",56),E(S,"UNITS_UNKNOWN",0),E(S,"UNITS_METER",1),E(S,"UNITS_MM",2),E(S,"UNITS_MICRON",3),E(S,"UNITS_SEC",8),E(S,"UNITS_MSEC",16),E(S,"UNITS_USEC",24),E(S,"UNITS_HZ",32),E(S,"UNITS_PPM",40),E(S,"UNITS_RADS",48),E(S,"MAGIC_COOKIE",348),E(S,"STANDARD_HEADER_SIZE",348),E(S,"MAGIC_NUMBER_LOCATION",344),E(S,"MAGIC_NUMBER",[110,43,49]),E(S,"MAGIC_NUMBER2",[110,105,49]),E(S,"EXTENSION_HEADER_SIZE",8);he.NIFTI1=S});var Be=It(ce=>{"use strict";Object.defineProperty(ce,"__esModule",{value:!0});ce.NIFTI2=void 0;var tt=ue(),w=jt(),Pt=class{littleEndian=!1;dim_info=0;dims=[];intent_p1=0;intent_p2=0;intent_p3=0;intent_code=0;datatypeCode=0;numBitsPerVoxel=0;slice_start=0;slice_end=0;slice_code=0;pixDims=[];vox_offset=0;scl_slope=1;scl_inter=0;xyzt_units=0;cal_max=0;cal_min=0;slice_duration=0;toffset=0;description="";aux_file="";intent_name="";qform_code=0;sform_code=0;quatern_b=0;quatern_c=0;quatern_d=0;qoffset_x=0;qoffset_y=0;qoffset_z=0;affine=[[1,0,0,0],[0,1,0,0],[0,0,1,0],[0,0,0,1]];magic="0";extensionFlag=[0,0,0,0];extensions=[];extensionSize=0;extensionCode=0;readHeader(t){var e=new DataView(t),n=w.Utils.getIntAt(e,0,this.littleEndian),r,a,s,l,o;if(n!==Pt.MAGIC_COOKIE&&(this.littleEndian=!0,n=w.Utils.getIntAt(e,0,this.littleEndian)),n!==Pt.MAGIC_COOKIE)throw new Error("This does not appear to be a NIFTI file!");for(this.magic=w.Utils.getStringAt(e,4,12),this.datatypeCode=w.Utils.getShortAt(e,12,this.littleEndian),this.numBitsPerVoxel=w.Utils.getShortAt(e,14,this.littleEndian),r=0;r<8;r+=1)l=16+r*8,this.dims[r]=w.Utils.getLongAt(e,l,this.littleEndian);for(this.intent_p1=w.Utils.getDoubleAt(e,80,this.littleEndian),this.intent_p2=w.Utils.getDoubleAt(e,88,this.littleEndian),this.intent_p3=w.Utils.getDoubleAt(e,96,this.littleEndian),r=0;r<8;r+=1)l=104+r*8,this.pixDims[r]=w.Utils.getDoubleAt(e,l,this.littleEndian);for(this.vox_offset=w.Utils.getLongAt(e,168,this.littleEndian),this.scl_slope=w.Utils.getDoubleAt(e,176,this.littleEndian),this.scl_inter=w.Utils.getDoubleAt(e,184,this.littleEndian),this.cal_max=w.Utils.getDoubleAt(e,192,this.littleEndian),this.cal_min=w.Utils.getDoubleAt(e,200,this.littleEndian),this.slice_duration=w.Utils.getDoubleAt(e,208,this.littleEndian),this.toffset=w.Utils.getDoubleAt(e,216,this.littleEndian),this.slice_start=w.Utils.getLongAt(e,224,this.littleEndian),this.slice_end=w.Utils.getLongAt(e,232,this.littleEndian),this.description=w.Utils.getStringAt(e,240,240+80),this.aux_file=w.Utils.getStringAt(e,320,320+24),this.qform_code=w.Utils.getIntAt(e,344,this.littleEndian),this.sform_code=w.Utils.getIntAt(e,348,this.littleEndian),this.quatern_b=w.Utils.getDoubleAt(e,352,this.littleEndian),this.quatern_c=w.Utils.getDoubleAt(e,360,this.littleEndian),this.quatern_d=w.Utils.getDoubleAt(e,368,this.littleEndian),this.qoffset_x=w.Utils.getDoubleAt(e,376,this.littleEndian),this.qoffset_y=w.Utils.getDoubleAt(e,384,this.littleEndian),this.qoffset_z=w.Utils.getDoubleAt(e,392,this.littleEndian),a=0;a<3;a+=1)for(s=0;s<4;s+=1)l=400+(a*4+s)*8,this.affine[a][s]=w.Utils.getDoubleAt(e,l,this.littleEndian);this.affine[3][0]=0,this.affine[3][1]=0,this.affine[3][2]=0,this.affine[3][3]=1,this.slice_code=w.Utils.getIntAt(e,496,this.littleEndian),this.xyzt_units=w.Utils.getIntAt(e,500,this.littleEndian),this.intent_code=w.Utils.getIntAt(e,504,this.littleEndian),this.intent_name=w.Utils.getStringAt(e,508,508+16),this.dim_info=w.Utils.getByteAt(e,524),e.byteLength>Pt.MAGIC_COOKIE&&(this.extensionFlag[0]=w.Utils.getByteAt(e,540),this.extensionFlag[1]=w.Utils.getByteAt(e,540+1),this.extensionFlag[2]=w.Utils.getByteAt(e,540+2),this.extensionFlag[3]=w.Utils.getByteAt(e,540+3),this.extensionFlag[0]&&(this.extensions=w.Utils.getExtensionsAt(e,this.getExtensionLocation(),this.littleEndian,this.vox_offset),this.extensionSize=this.extensions[0].esize,this.extensionCode=this.extensions[0].ecode))}toFormattedString(){var t=w.Utils.formatNumber,e="";return e+="Datatype = "+ +this.datatypeCode+" ("+this.getDatatypeCodeString(this.datatypeCode)+`)
`,e+="Bits Per Voxel =  = "+this.numBitsPerVoxel+`
`,e+="Image Dimensions (1-8): "+this.dims[0]+", "+this.dims[1]+", "+this.dims[2]+", "+this.dims[3]+", "+this.dims[4]+", "+this.dims[5]+", "+this.dims[6]+", "+this.dims[7]+`
`,e+="Intent Parameters (1-3): "+this.intent_p1+", "+this.intent_p2+", "+this.intent_p3+`
`,e+="Voxel Dimensions (1-8): "+t(this.pixDims[0])+", "+t(this.pixDims[1])+", "+t(this.pixDims[2])+", "+t(this.pixDims[3])+", "+t(this.pixDims[4])+", "+t(this.pixDims[5])+", "+t(this.pixDims[6])+", "+t(this.pixDims[7])+`
`,e+="Image Offset = "+this.vox_offset+`
`,e+="Data Scale:  Slope = "+t(this.scl_slope)+"  Intercept = "+t(this.scl_inter)+`
`,e+="Display Range:  Max = "+t(this.cal_max)+"  Min = "+t(this.cal_min)+`
`,e+="Slice Duration = "+this.slice_duration+`
`,e+="Time Axis Shift = "+this.toffset+`
`,e+="Slice Start = "+this.slice_start+`
`,e+="Slice End = "+this.slice_end+`
`,e+='Description: "'+this.description+`"
`,e+='Auxiliary File: "'+this.aux_file+`"
`,e+="Q-Form Code = "+this.qform_code+" ("+this.getTransformCodeString(this.qform_code)+`)
`,e+="S-Form Code = "+this.sform_code+" ("+this.getTransformCodeString(this.sform_code)+`)
`,e+="Quaternion Parameters:  b = "+t(this.quatern_b)+"  c = "+t(this.quatern_c)+"  d = "+t(this.quatern_d)+`
`,e+="Quaternion Offsets:  x = "+this.qoffset_x+"  y = "+this.qoffset_y+"  z = "+this.qoffset_z+`
`,e+="S-Form Parameters X: "+t(this.affine[0][0])+", "+t(this.affine[0][1])+", "+t(this.affine[0][2])+", "+t(this.affine[0][3])+`
`,e+="S-Form Parameters Y: "+t(this.affine[1][0])+", "+t(this.affine[1][1])+", "+t(this.affine[1][2])+", "+t(this.affine[1][3])+`
`,e+="S-Form Parameters Z: "+t(this.affine[2][0])+", "+t(this.affine[2][1])+", "+t(this.affine[2][2])+", "+t(this.affine[2][3])+`
`,e+="Slice Code = "+this.slice_code+`
`,e+="Units Code = "+this.xyzt_units+" ("+this.getUnitsCodeString(tt.NIFTI1.SPATIAL_UNITS_MASK&this.xyzt_units)+", "+this.getUnitsCodeString(tt.NIFTI1.TEMPORAL_UNITS_MASK&this.xyzt_units)+`)
`,e+="Intent Code = "+this.intent_code+`
`,e+='Intent Name: "'+this.intent_name+`"
`,e+="Dim Info = "+this.dim_info+`
`,e}getExtensionLocation=function(){return Pt.MAGIC_COOKIE+4};getExtensionSize=tt.NIFTI1.prototype.getExtensionSize;getExtensionCode=tt.NIFTI1.prototype.getExtensionCode;addExtension=tt.NIFTI1.prototype.addExtension;removeExtension=tt.NIFTI1.prototype.removeExtension;getDatatypeCodeString=tt.NIFTI1.prototype.getDatatypeCodeString;getTransformCodeString=tt.NIFTI1.prototype.getTransformCodeString;getUnitsCodeString=tt.NIFTI1.prototype.getUnitsCodeString;getQformMat=tt.NIFTI1.prototype.getQformMat;convertNiftiQFormToNiftiSForm=tt.NIFTI1.prototype.convertNiftiQFormToNiftiSForm;convertNiftiSFormToNEMA=tt.NIFTI1.prototype.convertNiftiSFormToNEMA;nifti_mat33_mul=tt.NIFTI1.prototype.nifti_mat33_mul;nifti_mat33_determ=tt.NIFTI1.prototype.nifti_mat33_determ;toArrayBuffer(t=!1){let r=544;if(t)for(let o of this.extensions)r+=o.esize;let a=new Uint8Array(r),s=new DataView(a.buffer);s.setInt32(0,540,this.littleEndian),a.set(Buffer.from(this.magic),4),s.setInt16(12,this.datatypeCode,this.littleEndian),s.setInt16(14,this.numBitsPerVoxel,this.littleEndian);for(let o=0;o<8;o++)s.setBigInt64(16+8*o,BigInt(this.dims[o]),this.littleEndian);s.setFloat64(80,this.intent_p1,this.littleEndian),s.setFloat64(88,this.intent_p2,this.littleEndian),s.setFloat64(96,this.intent_p3,this.littleEndian);for(let o=0;o<8;o++)s.setFloat64(104+8*o,this.pixDims[o],this.littleEndian);s.setBigInt64(168,BigInt(this.vox_offset),this.littleEndian),s.setFloat64(176,this.scl_slope,this.littleEndian),s.setFloat64(184,this.scl_inter,this.littleEndian),s.setFloat64(192,this.cal_max,this.littleEndian),s.setFloat64(200,this.cal_min,this.littleEndian),s.setFloat64(208,this.slice_duration,this.littleEndian),s.setFloat64(216,this.toffset,this.littleEndian),s.setBigInt64(224,BigInt(this.slice_start),this.littleEndian),s.setBigInt64(232,BigInt(this.slice_end),this.littleEndian),a.set(Buffer.from(this.description),240),a.set(Buffer.from(this.aux_file),320),s.setInt32(344,this.qform_code,this.littleEndian),s.setInt32(348,this.sform_code,this.littleEndian),s.setFloat64(352,this.quatern_b,this.littleEndian),s.setFloat64(360,this.quatern_c,this.littleEndian),s.setFloat64(368,this.quatern_d,this.littleEndian),s.setFloat64(376,this.qoffset_x,this.littleEndian),s.setFloat64(384,this.qoffset_y,this.littleEndian),s.setFloat64(392,this.qoffset_z,this.littleEndian);let l=this.affine.flat();for(let o=0;o<12;o++)s.setFloat64(400+8*o,l[o],this.littleEndian);if(s.setInt32(496,this.slice_code,this.littleEndian),s.setInt32(500,this.xyzt_units,this.littleEndian),s.setInt32(504,this.intent_code,this.littleEndian),a.set(Buffer.from(this.intent_name),508),s.setUint8(524,this.dim_info),t){a.set(Uint8Array.from([1,0,0,0]),540);let o=this.getExtensionLocation();for(let f of this.extensions)s.setInt32(o,f.esize,f.littleEndian),s.setInt32(o+4,f.ecode,f.littleEndian),a.set(new Uint8Array(f.edata),o+8),o+=f.esize}else a.set(new Uint8Array(4).fill(0),540);return a.buffer}},At=Pt;E(At,"MAGIC_COOKIE",540),E(At,"MAGIC_NUMBER_LOCATION",4),E(At,"MAGIC_NUMBER",[110,43,50,0,13,10,26,10]),E(At,"MAGIC_NUMBER2",[110,105,50,0,13,10,26,10]);ce.NIFTI2=At});var dn=It(q=>{var en=q&&q.__createBinding||(Object.create?function(i,t,e,n){n===void 0&&(n=e);var r=Object.getOwnPropertyDescriptor(t,e);(!r||("get"in r?!t.__esModule:r.writable||r.configurable))&&(r={enumerable:!0,get:function(){return t[e]}}),Object.defineProperty(i,n,r)}:function(i,t,e,n){n===void 0&&(n=e),i[n]=t[e]}),nn=q&&q.__setModuleDefault||(Object.create?function(i,t){Object.defineProperty(i,"default",{enumerable:!0,value:t})}:function(i,t){i.default=t}),rn=q&&q.__importStar||function(i){if(i&&i.__esModule)return i;var t={};if(i!=null)for(var e in i)e!=="default"&&Object.prototype.hasOwnProperty.call(i,e)&&en(t,i,e);return nn(t,i),t};Object.defineProperty(q,"__esModule",{value:!0});q.readExtensionData=q.readExtension=q.readImage=q.hasExtension=q.readHeader=q.decompress=q.isCompressed=q.isNIFTI=q.isNIFTI2=q.isNIFTI1=q.NIFTIEXTENSION=q.Utils=q.NIFTI2=q.NIFTI1=void 0;var sn=rn(Ci()),at=ue(),ct=Be(),wi=jt(),an=ue();Object.defineProperty(q,"NIFTI1",{enumerable:!0,get:function(){return an.NIFTI1}});var on=Be();Object.defineProperty(q,"NIFTI2",{enumerable:!0,get:function(){return on.NIFTI2}});var ln=jt();Object.defineProperty(q,"Utils",{enumerable:!0,get:function(){return ln.Utils}});var fn=Oe();Object.defineProperty(q,"NIFTIEXTENSION",{enumerable:!0,get:function(){return fn.NIFTIEXTENSION}});function Pe(i,t=!1){var e,n,r,a;return i.byteLength<at.NIFTI1.STANDARD_HEADER_SIZE?!1:(e=new DataView(i),e&&(n=e.getUint8(at.NIFTI1.MAGIC_NUMBER_LOCATION)),r=e.getUint8(at.NIFTI1.MAGIC_NUMBER_LOCATION+1),a=e.getUint8(at.NIFTI1.MAGIC_NUMBER_LOCATION+2),t&&n===at.NIFTI1.MAGIC_NUMBER2[0]&&r===at.NIFTI1.MAGIC_NUMBER2[1]&&a===at.NIFTI1.MAGIC_NUMBER2[2]?!0:n===at.NIFTI1.MAGIC_NUMBER[0]&&r===at.NIFTI1.MAGIC_NUMBER[1]&&a===at.NIFTI1.MAGIC_NUMBER[2])}q.isNIFTI1=Pe;function be(i,t=!1){var e,n,r,a;return i.byteLength<at.NIFTI1.STANDARD_HEADER_SIZE?!1:(e=new DataView(i),n=e.getUint8(ct.NIFTI2.MAGIC_NUMBER_LOCATION),r=e.getUint8(ct.NIFTI2.MAGIC_NUMBER_LOCATION+1),a=e.getUint8(ct.NIFTI2.MAGIC_NUMBER_LOCATION+2),t&&n===ct.NIFTI2.MAGIC_NUMBER2[0]&&r===ct.NIFTI2.MAGIC_NUMBER2[1]&&a===ct.NIFTI2.MAGIC_NUMBER2[2]?!0:n===ct.NIFTI2.MAGIC_NUMBER[0]&&r===ct.NIFTI2.MAGIC_NUMBER[1]&&a===ct.NIFTI2.MAGIC_NUMBER[2])}q.isNIFTI2=be;function hn(i,t=!1){return Pe(i,t)||be(i,t)}q.isNIFTI=hn;function Ni(i){var t,e,n;return!!(i&&(t=new DataView(i),e=t.getUint8(0),n=t.getUint8(1),e===wi.Utils.GUNZIP_MAGIC_COOKIE1||n===wi.Utils.GUNZIP_MAGIC_COOKIE2))}q.isCompressed=Ni;function Fi(i){return sn.decompressSync(new Uint8Array(i)).buffer}q.decompress=Fi;function un(i,t=!1){var e=null;return Ni(i)&&(i=Fi(i)),Pe(i,t)?e=new at.NIFTI1:be(i,t)&&(e=new ct.NIFTI2),e?e.readHeader(i):console.error("That file does not appear to be NIFTI!"),e}q.readHeader=un;function cn(i){return i.extensionFlag[0]!=0}q.hasExtension=cn;function vn(i,t){var e=i.vox_offset,n=1,r=1;i.dims[4]&&(n=i.dims[4]),i.dims[5]&&(r=i.dims[5]);var a=i.dims[1]*i.dims[2]*i.dims[3]*n*r*(i.numBitsPerVoxel/8);return t.slice(e,e+a)}q.readImage=vn;function gn(i,t){var e=i.getExtensionLocation(),n=i.extensionSize;return t.slice(e,e+n)}q.readExtension=gn;function pn(i,t){var e=i.getExtensionLocation(),n=i.extensionSize;return t.slice(e+8,e+n)}q.readExtensionData=pn});dn();})();