{ "cells": [ { "cell_type": "markdown", "metadata": {}, "source": [ "\n", "### A.L. Rae Centre Workshop on Genomic Prediction and Genome-Wide Association Studies\n", "\n", "### November 9-13, 2015\n", "\n", "### Coachman Hotel, Palmerston North, New Zealand\n", "\n", "\n", "### Course Instructors:\n", "* Dorian Garrick\n", "* Rohan Fernando\n", "\n", "\n", "### Topics Covered:\n", "*\tStatistical, quantitative genetic, and computational aspects of genomic prediction.\n", "*\tGenome-wide association studies using genomic prediction methods\n", "*\tJulia scripts for genomic prediction and GWAS\n", "\n", "\n", "### Prerequisites: \n", "* Graduate-level course in quantitative genetics.\n", "* Graduate-level course in statistics.\n", "* Basic understanding of concepts in QTL mapping, linkage, linkage disequilibrium and computer programming." ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "### Notes:\n", "\n", "* Day 1:\n", " * [Introduction to Genomic Prediction](Slides/Introduction.pdf)\n", " * [Simple Linear Models](Slides/Simple_Linear_Models.pdf)\n", " * Simulation of data using Julia \n", " ([notebook](JupyterNoteBooks/dataSimulation.ipynb), [slides](JupyterNoteBooks/dataSimulation.slides.html))\n", "* Day 2: \n", " * [Monte-Carlo Integration](JupyterNoteBooks/MonteCarlo.ipynb)\n", " * Bayes' Theorem\n", " ([notebook](JupyterNoteBooks/BayesTheorem.ipynb),[slides](JupyterNoteBooks/BayesTheorem.slides.html))\n", " * [Introduction to MCMC Sampling](JupyterNoteBooks/MonteCarlo.ipynb#mcmc)\n", " * [Interactive Plot of Gibbs and MH Samplers](JupyterNoteBooks/interactive_MH_Gibbs.ipynb)\n", " * [Introduction to MCMC](JupyterNoteBooks/MonteCarlo.ipynb#mcmc)\n", "* Day 3:\n", " * [Linear Regression Script: Inefficient](JuliaScripts/InefficientLinearRegressionMCMCwithknownResVar.jl.txt)\n", " * [Linear Regression Script: Efficient](JuliaScripts/LinearRegressionMCMCwithknownResVar.jl)\n", " * [Linear Regression Script: Unknown Variance](JuliaScripts/LinearRegressionMCMCwithUnknownResVar.jl)\n", " * [Bayesian Inference](JupyterNoteBooks/BayesInference.ipynb)\n", " * [Bayesian Inference by Application to Simple Linear Regression](JupyterNoteBooks/BayesSimpleLinear.ipynb)\n", " * [Bayesian Simple Linear Regression: Solutions](JupyterNoteBooks/BayesSimpleLinearHW.ipynb)\n", " * [Pedigree-based Mixed Linear Models](Slides/PedigreeBLUP.pdf)\n", " * [Problem 1](HWProblems/Problem1.pdf)\n", " * [BLUP Example](JuliaScripts/BLUPexample.jl)\n", " " ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "### Julia Tutorial:\n", "\n", "* [Learn X in Y minutes](http://learnxinyminutes.com/docs/julia/)\n", "* [Introduction to Julia for Statistical Genetics](http://reworkhow.github.io/JuliaGenBook/)\n", "* [Package Management](http://nbviewer.ipython.org/github/reworkhow/GPW2015/blob/master/notes/Pkg.ipynb)" ] } ], "metadata": { "kernelspec": { "display_name": "Julia 0.4.0", "language": "julia", "name": "julia-0.4" }, "language_info": { "file_extension": ".jl", "mimetype": "application/julia", "name": "julia", "version": "0.4.0" } }, "nbformat": 4, "nbformat_minor": 0 }