install.packages("BiocManager")
BiocManager::install(c("limma", 
                       "org.Hs.eg.db", 
                       "RColorBrewer", 
                       "TxDb.Hsapiens.UCSC.hg38.knownGene",
                       "goseq",
                       "fgsea",
                       "DESeq2",
                       "pheatmap",
                       "rmarkdown",
                       "tximport",
                       "clusterProfiler",
                       "DOSE",
                       "pathview",
                       "biomaRt",
                       "dplyr",
                       "ggplot2"),suppressUpdates=TRUE)