]> http://purl.bioontology.org/ontology/npo 2013-05-31 (yyyy-mm-dd) The NPO was primarily developed by Dennis G. Thomas in collaboration with Nathan A. Baker and Rohit V. Pappu. This development was supported by the NIH through grants U54 CA119342 and U54 HG004028. Dennis G. Thomas NanoParticle Ontology (NPO): An ontology for representing the knowledge underlying the description and characterization of nanoparticles. Relation between a continuant and an occurrent in which the continuant participates in and causes the occurrence of that occurrent. This relation is taken from the Ontology for Biomedical Investigations (OBI: Version 2009-11-06 Philly (aka version 1.0) Release Candidate) agent in A relation that indicates the process, property, or substance analyzed in an assay. analyzes A relation between an entity and a dependent continuant. bearer of (source): OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005) A relation between a material continuant and an immaterial continuant, when the material continuant at any given time is located in but shares no parts in common with the immaterial continuant at the same time. C contained_in C1; Cs are material continuants, C1s are immaterial continuants (holes, cavities): Every C at any given time is located in but shares no parts in common with C1 at the same time. contained in (source): OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005) A reciprocal relation of contained_in, where given an immaterial continuant at some time, there is a material continuant contained in the immaterial continuant at the same time. C contains C1; Cs are immaterial continuants, C1s are material continuants: for all C, t, , if c is an instance of C at time t, then there is some c1 such that c1 is an instance of C1 and c1 contained_in c at t. contains A relation which indicates the symbol that denotes something. denoted by A relation between distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a significant portion of the matter of the earlier continuant is inherited by the later. The temporal relation of derivation is more complex. Transformation, on the instance level, is just the relation of identity: each adult is identical to some child existing at some earlier time. Derivation on the instance-level is a relation holding between non-identicals. More precisely, it holds between distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a biologically significant portion of the matter of the earlier continuant is inherited by the later. Thus we will have axioms to the effect that from c derives_from c1 we can infer that c and c1 are not identical and that there is some instant of time t such that c1 exists only prior to and c only subsequent to t. We will also be able to infer that the spatial region occupied by c as it begins to exist at t overlaps with the spatial region occupied by c1 as it ceases to exist in the same instant. [source]:OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005) derives from A relation which indicates the property determined by a characterization. determines property document attribute A relationship that indicates the bearer inhering a function. function of has DOI has PubMedID has abstract (source): OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005) A relation which is between a process, a continuant and a time whenever the continuant is a participant in the process and is at the same time directly causally responsible for its occurrence. Only material continuants can fill the agent role, that if c fills the agent role at t, then c must have existed at times earlier than t, that it must exercise its agent role for an interval of time including t, and so on. P has_agent C; Ps are processes, Cs are material continuants. Every P involves some C as agent (the C is involved in and is causally responsible for the P) has agent A relation which indicates the application or use of an entity. has application has author A relationship to indicate that one atom has a covalent bond with another atom. has bond with A relation used between material continuants where one is composed of the other. In the NPO, this relation is used mostly for representing the composition of nanoparticle formulations or nanoparticles. C has_component_part C1, means that every instance c of C is prepared from some instances c1 of C1 and a significant material portion of c1 becomes part of the constituting material of c when c begins to exist. has component part is composed of A has_component_part type of relation, which is used to infer that a particular component in a nanoparticle formulation is attached or chemically conjugated to some other chemical components of the same nanoparticle formulation by a method of attachment. has attached component part has conjugated component part A relation which indicates the value of a property that can be quantified. has datum value A relationship to indicate that one atom has a double covalent bond with another atom. has double bond with A has_component_part type of relation, which is used to infer that a particular component (molecular structure or nanostructure) becomes encapsulated - due to non-covalent interactions - in a nanoparticle by a method of encapsulation. has encapsulated component part A relation that indicates the endpoint measured with an assay. has endpoint of measurement A has_component_part type of relation, which is used to infer that a particular component (molecular structure or nanostructure) is entrapped - due to non-covalent interactions - in a nanoparticle by a method of entrapment. has entrapped component part A relationship that indicates the function inhering in an entity. has function A relation which indicates the name of the type of identification, as well as other attributes of an entity. has identification type has journal name A relationship between a continuant and an occurrent that has other participating continuants, which holds if at every time t an instance of the occurrent is created, there is at least one instance of the continuant participating in it at time t1 > t, and it is formed / derived from the instances of those continuants that participate at time t. has output participant (source): OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005) If C and C1 are continuant classes, then C has_part C1 means that every instance of C at any time has part some instances of C1 at the same time. [formal definition]: C has_part C1 holds true if and only if every continuant c that instantiates C at some time t, there is some continuant c1 that instantiates C1 at t such that c1 is part of c at t. Examples: fluorescein isothiocyanate has_part isothiocyanate group gold quantum dot has_part gold core-shell nanoparticle has_part core core-shell nanoparticle has_part shell If P and P1 are occurrent classes, then P has_part P1 means that every instance of P has part some instances of P1. [formal definition]:P has_part P1 if and only if every occurrent p that instantiates P there is some occurrent p1 that instantiates P1 such that p1 is part of p. Examples: covalent linkage has_part covalent interaction visualization of cellular uptake of nanoparticles has_part imaging of nanoparticles Transitive parthood relation in which one entity has itself, or another entity as a part, and the relation is valid for use only between continuants or between occurrents but not between a continuant and an occurrent. has part (source): OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005) A relationship between a continuant and an occurrent, which holds if at every time an instance of the occurrent is created, it has at least one instance of the continuant participating in it at the same time. Examples: nanoparticle-mediated drug delivery has_participant drug-loaded nanoparticle If P is an occurrent class and C a continuant class, then P has_participant C means that every instance of P involves some instances of C as participants. [formal definition]: P has_participant C hold true, if and only if every occurrent p that instantiates P there is some continuant c, and some time t, such that c instantiates C at t and p has participant c at t. has participant A relation between an entity and a specifically dependent continuant. has property has publication year A relation which indicates the quality inhering in an entity. It is a general relation between any class and subclasses of Quality. has quality A relationship to indicate that a class is related to another class. has relation to If C is an independent continuant and C1 a role continuant class, then C has_role R1 means that every instance of C fills some instances of role C1 everytime the role is realized in a particular context. Relation between an independent continuant and a role. [source]: OBO Relation Ontology (release version 0.99, date 07:14:2006) e.g., X (molecular entity) has_role Y (role), i.e, X fills the role of Y has role A relationship to indicate that one atom has a single covalent bond with another atom. has single bond with A relation that indicates the temperature at which a process is performed. has temperature condition A relation that indicates the duration for a process to occur. has time period has title A relationship to indicate that one atom has a triple covalent bond with another atom. has triple bond with A relation which indicates the unit of a measured quantity. has unit has unit of measure A relation between a dependent continuant D and an entity E. D inheres_in E if: given any d that instantiates D at t, there exists some e that instantiates E at t and d *inheres_in* e at t. Here *inheres_in* is the primitive instance level relation. [source: OBI] inheres in A relation that indicates the process or phenomenon signified by a measured endpoint of an assay. indicator of A parthood relation that holds when C is part of C and C1 has part C, where C and C1 are continuant classes. [source]: OBO Relation Ontology (release version 0.99); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005) e.g.,carbon atom is_integral_part_of carbon (carbon is_a element) is integral part of A relationship between a realizable entity and an occurrent. This relation is taken from the Ontology for Biomedical Investigations (OBI: Version 2009-11-06 Philly (aka version 1.0) Release Candidate) executed during has realization is realized as is realized by is realized in A relation which indicates a qualitative or quantitative measure (estimate) of an entity based on measurement, calculation, or counting. measure of A relation between two occurrents where one negatively regulates the other. blocks inhibits negatively regulates A relation which indicates the type of process that determines the value of a parameter. parameter determined from If C and C1 are continuant classes, then C part_of C1 means that every instance of C (c) at any time is part of some instances of C1 (c1) at the same time []. Note that whenever we read "some instances" it should be understood as reading "one or more instances". [formal definition]: C part_of C1 holds true if and only if every continuant c that instantiates C at some time t, there is some continuant c1 that instantiates C1 at t such that c is part of c1 at t. Examples: carboxyl group part_of carboxylic acid dendrimer generation layer part_of dendrimer hydrophobic core of lipid bilayer part_of lipid bilayer hollow core of nanocage part_of nanocage If P and P1 are occurrent classes, then P part_of P1 means that every instance of P is part of some instances of P1. [formal definition]: P part_of P1 holds true if and only if every occurrent p that instantiates P there is some process p1 that instantiates P1 such that p is part of p1. Examples: drug release from nanoparticle during systemic circulation part_of systemic circulation of drug-loaded nanoparticle Transitive parthood relation in which one entity is part of another entity, and the relation is valid for use between continuants or between occurrents but not between a continuant and an occurrent. [source]: OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005) is part of part of A relationship between a continuant and an occurrent, which holds iff at every time an instance of the continuant is created, it participates in at least one instance of the occurrent at the same time. Example: catalyst participates_in catalytic reaction fluorometer participates_in measurement of fluorescence intensity If C is a continuant class and P an occurrent class, then C participates_in P means that every instance of C participates in some instances of P. [formal definition]: C participates_in P if and only if every continuant c that instantiates C there is some occurrent p, and some time t, such that p instantiates P and c participates in p at t. [source]: OBO Relation Ontology (release version 0.99, date 07:14:2006) is_participant_of participates in A relation between two occurrents where one positively regulates the other. positively regulates A relation which indicates the type of process that determines a qualitative or quantitative measure of the property. property determined from A relation which indicates the entity which bears a property. property of A relation between a quality and its bearer. quality inheres in quality of A relation between an occurrent to a realizable entity. is realization of realizes A relationship between two occurrents where one regulates the other. regulates A relationship indicating the bearer inhering a role. role of A relationship that indicates the response caused by a stimulus. (e.g., the response caused by the action of a stimulus on a nanoparticle) stimulus causes response A relationship which indicates the principle based on which a technique is used. technique is based on A relation which indicates the process for which the technique is used. technique used for A relation that indicates the quantity associated with a unit of measure. It is an inverse relation of "has unit of measure". unit of A relation which indicates that the type of instrument used in a process. uses instrument A relation which indicates the reagent used in an assay. uses reagent A relation which indicates the technique used for accomplishing a purpose. uses technique This relation is used to indicate other datum values that have to be specified/recorded when a particular datum value is recorded. value specified at Concept_Status Used to support NCI Edit tab DesignNote Used to support Merge and Retire Editor_Note Used to support Merge and Retire FULL_SYN This property is in support of the NCI Edit Tab. Merge_Into Used to support Merge and Retire Merge_Source Used to support Merge and Retire Merge_Target Used to support Merge and Retire OLD_CHILD Used to support Merge and Retire OLD_PARENT Used to support Merge and Retire OLD_ROLE Used to support Merge and Retire OLD_SOURCE_ROLE Used to support Merge and Retire Split_From Used to support Split The number of protons in an atom. atomic number code It begins with the prefix "NPO_" followed by a number (e.g., NPO_250). The smallest code value is NPO_100 of class Cylinder. The property code is used to indicate a unique identification code for every class in the NPO. dBXrefID The property dBXrefID is used to indicate the reference ID of a class from an external CV / ontology / database. definition The property definition is used to indicate the meaning or definition of a class or a class-level association in the NPO. preferred_name The property preferred name is used to indicate the preferred name of a class or a class-level association in the NPO. symbol The property symbol is used to enter a symbol that denotes the name of an entity. synonym The property synonym is used to indicate an alternate name of a class or a class-level association in the NPO. cylindrical shape <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape formed by the surface of a 3-dimensional object, where points on the surface are at a fixed distance from a given straight line (axis of the cylinder).</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cylindrical shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C63806 NPO_100 cylindrical cylindrical shape deoxyribonucleic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nucleic acid composed of nucleotides containing deoxyribose sugar and linked by phosphodiester bonds. DNA contains the genetic information of organisms.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>deoxyribonucleic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DNA NPO_1002 deoxyribonucleic acid halogen <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A non-metal which is any of the following elements: astatine, bromine, chlorine, fluorine, iodine.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>halogen</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_101 halogen nano-object <ncicp:ComplexDefinition><ncicp:def-definition>A nanomaterial which has one, two, or three external dimensions in the nanoscale size range.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nano-object</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1018 This term had the preferred name "nanostructure" in version 2010-10-31. nano-object homoatomic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a molecular entity because it consists of one or more atoms of the same element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>homoatomic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1019 homoatomic prolate spheroidal shape <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spheroidal shape, which is generated by half-revolution of an ellipse around its major axis.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>prolate spheroidal shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_102 prolate spheroidal shape polyatomic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a molecular entity because it consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polyatomic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1020 polyatomic monoatomic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a molecular entity because it consists of only one atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>monoatomic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1021 monoatomic heteroatomic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a molecular entity because it consists of two or more chemical elements.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>heteroatomic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1022 heteroatomic aluminium atom 13 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 13.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>aluminium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_103 aluminium atom methotrexate-loaded nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is loaded with methotrexate.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>methotrexate-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_104 methotrexate-loaded nanoparticle Group 16 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 16 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Group 16 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Group 16 Element NPO_105 chalogen hydrophilic core of liposome <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The aqueous space enclosed by lipid bilayer of a liposome.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrophilic core of liposome</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_106 hydrophilic core of liposome strontium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 38.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>strontium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_107 strontium bohrium atom 107 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 107.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>bohrium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_108 bohrium atom lipid-coated nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a coating agent composed of a lipid.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lipid-coated nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_109 lipid-coated nanoparticle carboxylate <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carboxylate is an organic compound which is characterized by the presence of a carboxylate group. It has the structure R-C(=O)-[O-], where 'R' denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carboxylate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_110 carboxylate francium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 87.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>francium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_111 francium carbon molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of carbon.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carbon molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1113 carbon molecular entity multi-walled nanotube <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanotube which consists of multiple layers or sheets of hexagonal arrays of an element or molecule, rolled in on themselves to form concentric seamless cylinders with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>multi-walled nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_112 multi-walled nanotube acyl chloride group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl halide group in which the halogen atom is a chlorine atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>acyl chloride group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_113 acyl chloride group lipophilic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrophobic property by virtue of which the molecule is able to combine with or dissolve in lipids or fats.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lipophilic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_114 lipophilic lipophilicity nanodevice <ncicp:ComplexDefinition><ncicp:def-definition>An engineered nanomaterial which has an end-directed activity/function.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanodevice</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_115 nanodevice polydispersity index <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative measure of polydispersity. It is a measure of the distribution of molecular mass in a given polymer sample or the distribution of particle sizes in a particulate sample. In polymeric samples, the polydispersity index is calculated as the weight average molecular weight divided by the number average molecular weight.</ncicp:def-definition><ncicp:Definition_Review_Date>100727</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polydispersity index</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1155 PDI polydispersity index weight ratio <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dimensionless unit which denotes the ratio of weights.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>weight ratio</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1156 weight ratio magnetic flux <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quantitative measure of magnetism, which is a measure of the strength of a magnetic field over a given area.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>magnetic flux</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1158 magnetic flux magnetic flux unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of measurement for magnetic flux.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>magnetic flux unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1159 magnetic flux unit unit of magnetic flux magnetic flux density <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The amount of magnetic flux in a unit area perpendicular to the direction of magnetic flow.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>magnetic flux density</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1163 magnetic flux density magnetic flux density unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of measurement for magnetic flux density.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>magnetic flux density unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1164 magnetic flux density unit unit of magnetic flux density concentration <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a substance by virtue of the amount of it there is mixed with another substance.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>concentration</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1167 PATO:0000033 concentration sulfonyl chloride group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which is derived by the removal of one chlorine atom from chlorosulfuric acid, and has the structure -S(=O)(=O)-Cl. The group is characteristic of sulfonyl chloride derivatives.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sulfonyl chloride group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_117 sulfonyl chloride group molecular weight <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The sum of the relative atomic masses of the constituent atoms of a molecule.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molecular weight</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MW NPO_1171 molecular weight chemical interaction <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A force of interaction between atoms, ions, molecules or groups.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chemical interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_119 chemical bonding chemical interaction molarity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The number of moles of a solute dissolved in a liter of solution.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molarity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1190 molar concentration molarity molality <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The number of moles of solute dissolved in one kilogram of solvent.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1191 molal concentration molality normality <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Concentration of a solution expressed in gram equivalents of solute per liter.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>normality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1192 normal concentration normality cell concentration <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Concentration, which is the amount of cells in a medium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cell concentration</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1193 cell concentration IC50 <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of toxicity which is the concentration of a drug or inhibitor that is required to inhibit a biological process or a participant's activity in that process by half. The realization of this realizable entity is the 50% inhibition of a biological process or the activity (molecular function) of a biological occurring chemical entity (e.g., gene, gene product)</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>IC50</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> IC50 NPO_1195 half maximal inhibitory concentration LC-50 <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of toxicity which is the concentration of a chemical or biologic preparation that is likely to cause death in 50% of animals or cells being tested. The realization of this realizable entity is the death of 50% of animals or cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>LC-50</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> LC-50 LD-50 NCIT:C16788 NPO_1196 lethal concentration - 50% lethal dose - 50% basic pH <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of value between 7 and 14.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>basic pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1199 alkaline pH basic pH polar aminoacid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aminoacid which is polar in nature.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polar aminoacid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_120 polar aminoacid acidic pH <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of value between 0 and 7.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>acidic pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1200 acidic pH neutral pH <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of value equal to 7.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>neutral pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1201 neutral pH alkaline <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A qualitative measure of acidity in the basic pH range.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>alkaline</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1202 alkaline basic acidic <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A qualitative measure of acidity in the acidic pH range.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>acidic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1203 acidic isoelectric point <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The pH at which a particular molecule or surface carries no net electrical charge.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>isoelectric point</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1204 isoelectric point cells per microliter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of cell concentration which is equal to one cell in a volume of 1 microliter.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cells per microliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C67242 NPO_1206 cells per microliter cells/µL alkali earth metal <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 2 (IUPAC style) of the periodic table: beryllium (Be), magnesium (Mg), calcium (Ca), strontium (Sr), barium (Ba) and radium (Ra).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>alkali earth metal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_121 alkali earth metal alkaline earth metal amount of substance <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which denotes the amount of substance (matter).</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>amount of substance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1217 amount of substance body weight <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Weight inhering in the body of an animal species.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>body weight</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1219 body weight nanorod <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A two-dimensional nanoparticle which is shaped like a long dowel and has diameter measured in the nanoscale.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanorod</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C62373 NPO_122 [NCI_Thesaurus definition]: Nanoscale structures that are shaped like long dowels. The structures have a diameter that is measured in the nanoscale with an extended length parameter. nanorod tumor weight <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Weight inhering in a tumor.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tumor weight</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1220 tumor weight surface area <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Area of an object's surface.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>surface area</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1235 surface area anti-adhesion agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antimetastic agent, which prevents metastasis by interfering with the aggregation of tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>anti-adhesion agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C2197 NPO_124 anti-adhesion agent Actinide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inner transition element which is any element in the series of 15 radioactive metallic elements with atomic numbers 89 (actinium) to 103 (lawrencium).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Actinide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Actinide NPO_125 square nanometer <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An area unit which is equal to 10^[-18] m^[2].</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>square nanometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1252 nm^[2] square nanometer nanotube <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A two-dimensional nanoparticle which consists of one or more sheets of hexagonal arrays of an element or molecule, rolled into seamless cylinders with capped ends.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C73455 NPO_126 nanotube microgram per milliliter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in micrograms divided by the volume in milliliters.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>microgram per milliliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1267 microgram per milliliter micrograms per milliliter µg/mL microgram per microliter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in micrograms divided by the volume in microliters.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>microgram per microliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1268 microgram per microliter micrograms per microliter µg/µL nanoparticle surface modifying role <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role of a surface modifying agent that is attached to the surface of a nanoparticle in a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoparticle surface modifying role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_127 nanoparticle surface modifying role iodoacetyl group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iodoacetyl group is an organic group which has the structure -C(=O)-CH2-I. The group is characteristic of an iodoacetyl molecule in which it is attached either to a hydrogen atom or a carbon atom via single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iodoacetyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_128 iodoacetyl group time quality <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a continuant bearer by virtue of its relation to time during its existence.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>time quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1285 time quality age <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A time quality inhering in a bearer by virtue of how long it has existed.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>age</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1286 PATO:0000011 age chlorine <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 17.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chlorine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_129 chlorine electric charge <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A property of matter responsible for electrical phenomena.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>electric charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1292 charge electric charge electric charge unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a measure of the quantity of charge.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>electric charge unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1293 charge unit electric charge unit selective estrogen receptor modulator <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anticancer drug that acts like estrogen on some tissues but blocks the effect of estrogen on other tissues.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>selective estrogen receptor modulator</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C1821 NPO_130 selective estrogen receptor modulator zeta potential <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The potential difference between the bulk dispersion medium (liquid) and the stationary layer of liquid near the surface of the dispersed particulate.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>zeta potential</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C62354 NPO_1302 zeta potential statcoulomb <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric charge unit which which is approximately equal to 3.33564 × 10^[?10] C.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>statcoulomb</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Fr Franklin NPO_1303 e.s.u. electrostatic unit of charge statC statcoulomb ampere hour <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of electric charge where one ampere-hour is equal to 3600 coulombs.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ampere hour</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Ah NPO_1304 amp hour ampere hour positive charge <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric charge quality which signifies a deficiency of electrons in the bearer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>positive charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1305 positive charge positively charged negative charge <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric charge quality which signifies a surplus of electrons in the bearer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>negative charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1306 negative charge negatively charged neutral charge <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric charge quality which signifies zero net charge in the bearer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>neutral charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1307 neutral charge neutrally charged rate <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity which inheres in a continuant or a group of continuants under certain conditions, and it is realized through the occurrence of a process, activity or interaction per unit time.</ncicp:def-definition><ncicp:Definition_Review_Date>100429</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>rate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1308 PATO:0000161 rate tumor suppression rate <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The rate of suppression in tumor growth.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tumor suppression rate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1309 rate of tumor suppression tumor suppression rate Period 1 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the first row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Period 1 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_131 Period 1 Element mass rate <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The rate of change or movement in the mass (amount of matter) of a physical object.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mass rate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1310 mass rate mass rate unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A measure of the change or movement of mass per unit time.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mass rate unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1311 mass rate unit unit of mass rate kilogram per day <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of mass rate expressed as kilograms per day.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>kilogram per day</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1312 kg/day kilogram per day kilograms per day electrophoretic mobility <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Mobility of a charged particle in electrophoresis, measured as the rate of migration (usually in cm/s) per unit electric field strength (usually V/cm) of the charged particle.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>electrophoretic mobility</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1315 electrophoretic mobility unit of electrophoretic mobility <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of measure of electrophoretic mobility.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>unit of electrophoretic mobility</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1317 unit of electrophoretic mobility square centimeter per volt per second <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of electrophoretic mobility of a charged particle moving with a velocity of 1cm/s in an electric field of strength equal to 1 volt/s.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>square centimeter per volt per second</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1318 cm^[2]/(V s) square centimeter per volt per second sulfonyl chloride derivative <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A sulfonyl chloride derivative is an organic compound which is characterized by the presence of a sulfonyl chloride group. It has the structure R-S(=O)(=O)-Cl, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sulfonyl chloride derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_132 sulfonyl chloride derivative mole percentage % mol <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A percentage unit of molar concentration which is equal to 100 times the mole fraction (number of moles of solute in proportion to the total number of moles in a solution.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mole percentage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1327 mol % mole percentage percent of total moles seaborgium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 106.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>seaborgium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_133 seaborgium efficiency <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity inhering in a bearer by virtue of ratio of the bearer's output to the bearer's input.</ncicp:def-definition><ncicp:Definition_Review_Date>100429</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>efficiency</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1333 PATO:0001029 efficiency loading efficiency <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a material entity by virtue of it having the capacity to carry an amount of another material entity.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>loading efficiency</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1334 loading efficiency transfection efficiency <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The efficiency inhering in a bearer's ability to facilitate transfection.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>transfection efficiency</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1335 transfection efficiency encapsulation efficiency <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The efficiency inhering in a nanomaterial or supramolecular structure by virtue of its capacity to encapsulate an amount of molecular entity, isotope or nanomaterial.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>encapsulation efficiency</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1336 encapsulation efficiency tumor volume <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 3-D extent quality of the amount of 3-dimensional space a tumor occupies.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tumor volume</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1337 tumor volume toxicity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity inhering in a bearer which causes harm to the growth and functioning of cells, tissues, organs and the body.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>toxicity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C27990 NPO_1338 toxicity immunotoxicity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Toxicity that impairs or damages the immune system.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>immunotoxicity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C63814 NPO_1339 immunotoxicity cytotoxicity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Toxicity that impairs or damages cells, and it is a desired property for the killing of growing tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cytotoxicity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C27988 NPO_1340 cytotoxicity drug toxicity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Toxicity that inheres in a drug which causes adverse effects, when the drug is used therapeutically or diagnostically.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>drug toxicity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C27955 NPO_1341 drug toxicity cell viability <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Viability of a cell to proliferate, grow, divide, or repair damaged cell components.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cell viability</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1343 cell viability chemical composition <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in an object by virtue of the type, quantities or relative ratios of chemical components of the inhering entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100701</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO:0000025 (composition)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>chemical composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1344 chemical composition purity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A composition quality which is the degree to which an object bearer is free of contaminants or heterogeneous components.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>purity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1345 purity amplitude of sound wave <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>The maximum magnitude (value without regard to sign) of the disturbance of a sound wave.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>amplitude of sound wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1351 PATO:0001521 amplitude of sound amplitude of sound wave sound amplitude characterization <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An experiment performed to determine the distinctive characteristics (property / behavior) or essential features of a material entity.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1355 characterization physicochemical characterization <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of characterization, which is performed to determine the physicochemical (material and structural) properties of an object.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>physicochemical characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1356 physicochemical characterization in vitro characterization <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of characterization, which is performed to determine a property/quality that indicates the behavior of a material entity in vitro.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>in vitro characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1357 in vitro characterization in vivo characterization <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of characterization, which is performed to determine a property/quality that indicates the behavior of a material entity in vivo.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>in vivo characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1358 in vivo characterization molecular weight characterization <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of physical characterization, which is performed to determine the molecular weight of a molecular entity.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molecular weight characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1359 molecular weight characterization antimitotic agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic agent that kills cancer cells by interfering with mitosis.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>antimitotic agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MESH: D050256 NCIT: C273 NPO_136 antimitotic agent purity characterization <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of physical characterization, which is performed to determine the purity of a chemical substance.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>purity characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1360 purity characterization shape characterization <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of physical characterization, which is performed to determine the shape of an object.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>shape characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1361 shape characterization size characterization <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of physical characterization, which is performed to determine the size of an object.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>size characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1362 size characterization surface characterization <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of physical characterization, which is performed to determine the surface property of an object.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>surface characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1363 surface characterization surface property <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A property inhering in the surface of an object.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>surface property</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1364 surface property aspect ratio <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dimensionless unit which denotes the ratio of longest and shortest dimensions of an object.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>aspect ratio</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1365 aspect ratio average diameter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A measure of diameter obtained by dividing a sum of several diameter values by the total number of values.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>average diameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1366 average diameter mean diameter coat <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fiat material part which is a thin outer layer or film of material covering the surface of an object (e.g., a nanoparticle).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>coat</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1367 coat coating surface coating magnetic nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has magnetic property.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>magnetic nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1370 magnetic nanoparticle silica nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of silicon dioxide.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>silica nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1373 silica nanoparticle silicon dioxide nanoparticle superparamagnetic iron oxide nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iron oxide nanoparticle which has superparamagnetic property.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>superparamagnetic iron oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1374 SPIO nanoparticle superparamagnetic iron oxide nanoparticle polymeric nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of polymer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polymeric nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1375 polymer nanoparticle polymeric nanoparticle fluorescent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition inhering in a bearer which emits light of longer wavelength during absorption of radiation of shorter (invisible) wavelength.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluorescent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1376 PATO:0000018 fluorescence property fluorescent fluorescent nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has fluorescence property.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluorescent nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1377 fluorescent nanoparticle hydrogel nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which exists while dispersed in a hydrogel.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrogel nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1378 hydrogel nanoparticle surface of nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The surface of a nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>surface of nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1379 nanoparticle surface surface of nanoparticle encapsulation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A linkage in which a molecular entity or nanostructure becomes enclosed due to non-covalent interactions, in a nanoparticle's material site that is fully bounded by the particle's constituting material.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>encapsulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_138 encapsulation radioisotope <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An isotope which releases radiation as it breaks down.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>radioisotope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C799 NPO_1380 radioisotope radionuclide radioactivity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Emission of particles or electromagnetic radiation caused by the spontaneous disintegration of atoms of unstable nuclei in order to form atoms with stable nuclei.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>radioactivity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1382 radioactive decay radioactivity radioactive <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition inhering in the bearer by virtue of it exhibiting or causing radioactivity.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>radioactive</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1383 PATO:0001741 radioactive metal nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of a metal.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>metal nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1384 metal nanoparticle metallic nanoparticle immunoglobulin <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antibody which has molecular mass of 150-950 kDa, and consists of one or more basic units of four polypeptide chains comprising of two heavy chains and two light chains held together by disulphide links.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>immunoglobulin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Ig NCIT:C572 NPO_1388 immunoglobulin immunoglobulin A <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An immunoglobulin isotype which is associated with antibody-mediated mucosal immunity. It is secreted as dimers into the mucosa and is the most effective isotype at fixing complement by the alternative pathway, even though it lacks the ability to fix complement by the classical pathway. There are two subtypes in the human - IgA1 and IgA2. [Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>immunoglobulin A</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> IgA NCIT:C565 NPO_1389 immunoglobulin A immunoglobulin D <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An immunoglobulin isotype, which is expressed on naive B cells along with IgM.[Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>immunoglobulin D</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> IgD NCIT:C566 NPO_1390 immunoglobulin D immunoglobulin E <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An immunoglobulin isotype, which has the unique ability to bind with high affinity to IgE receptors (FceRI) on mast cells and basophils and induce degranulation and cytokine production by these cells when they are crosslinked by antigen. In addition to a central role in atopy and allergic responses, it has been speculated that IgE-mediated mast cell degranulation, by its release of mediators that increase vascular permeability, has an important role in the initiation of immune response in general. [Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>immunoglobulin E</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> IgE NCIT:C567 NPO_1391 immunoglobulin E immunoglobulin G <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An immunoglobulin isotype, which characterizes secondary immune responses. This isotype is further broken down into several smaller subclasses (IgG1, IgG2a, IgG2b, IgG3 in the mouse; IgG1-4 in the human), and each subclass is differentially synthesized and secreted into the serum upon differential immune stimuli.[Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>immunoglobulin G</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> IgG NCIT:C568 NPO_1392 immunoglobulin G immunoglobulin M <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A main immunoglobulin isotype which is secreted during a primary immune response. IgM binds with low affinity but high avidity (multiple binding sites) because it not only occurs as monomers but also as pentamers and hexamers.[Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>immunoglobulin M</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> IgM NCIT:C569 NPO_1393 immunoglobulin M immunoglobulin isotype <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A class of immunoglobulins, which refers to genetic variations or differences in the constant region of the heavy chain of the Ig</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>immunoglobulin isotype</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1394 immunoglobulin class immunoglobulin isotype isotype targeting function <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A function which inheres in a material entity, and is realized in a process in which the material entity is used to target another material entity.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>targeting function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1395 targeting function imaging function <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A function inhering in a material entity by virtue of its use for imaging purposes.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>imaging function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1396 imaging function therapeutic function <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A function inhering in a material entity by virtue of its use for therapeutic purposes.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>therapeutic function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1397 therapeutic function acyl halide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl halide compound is an acyl compound which is characterized by the presence of acyl halide group. It has the structure R-(C=O)-X, where 'R' denotes an organic group and X denotes a halogen atom (F, Cl, Br or I).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>acyl halide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_140 acid halide acyl halide bioluminescence <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Chemiluminescence produced by living systems.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>bioluminescence</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1403 bioluminescence nanoparticle sample <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A small representative portion of a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoparticle sample</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1404 nanoparticle sample technique <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A systematic procedure or a practical method which is used for accomplishing a task.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1405 [DGT, June 10, 2010]: Description for a specific type of technique could contain the following types of information: 1) principle used in the technique (e.g. NMR for NMR spectroscopy), 2) description of the principle if the term that describes the principle is not represented in the ontology, 3) tool used in a technique (e.g., scanning electron microscope in scanning electron microscopy), 4) applications of the technique, and 5) information on how to use the technique for each type of application. technique procedure <ncicp:ComplexDefinition><ncicp:def-definition>A temporal interval which is the time during which a process continues to occur.</ncicp:def-definition><ncicp:Definition_Review_Date>130524</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>procedure</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1406 method procedure experiment <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scientific procedure which is a process of conducting a test under controlled conditions to make a discovery, test a hypothesis, or demonstrate a known fact.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>experiment</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1407 experiment assay <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An experiment which is used to 1) analyze or measure (qualitatively/quantitatively) the composition and property of a substance; or, 2) to analyze a process or activity.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1408 assay in vitro assay <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A bioassay conducted in an artificial environment (e.g., test tube) outside the body of a living organism, under controlled conditions.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>in vitro assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C15958 NPO_1409 in vitro assay in vitro bioassay thioether group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -S-. The group is characteristic of thioether wherein the sulfur atom is attached to two carbon atoms via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thioether group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_141 thioether group in vivo assay <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A bioassay conducted inside the body of a living organism.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>in vivo assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1410 in vivo assay in vivo bioassay bioassay <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An assay which is used to test or analyse the biological activity of a substance, and which is performed by studying its effect on an organism or in a test tube under controlled conditions.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>bioassay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1411 bioassay physical assay <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An assay for evaluating the physical properties of a sample.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>physical assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1412 physical assay nanoparticle characterization <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Characterization of nanoparticles or nanoparticle formulations.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoparticle characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1413 characterization of nanoparticle nanoparticle characterization emulsifier <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule used for stabilizing an emulsion.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>emulsifier</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1414 emulsifier emulsifying agent microscopy <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A technique which uses a microscope to study a material object or a process that cannot be seen by the naked eye.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1415 microscopy microscopy technique separation technique <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A technique which is used to separate substances from mixtures.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>separation technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1416 separation method separation technique centrifugation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A separation technique which uses a centrifuge to generate a centrifugal force for separating fluids of different densities from mixtures or for separating liquids from solids.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>centrifugation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1417 centrifugation electrophoresis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A separation technique used for separating charged particles in a fluid or gel under the action of an electric field. The electric field causes the movement of charged particles.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>electrophoresis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1418 electrophoresis gel electrophoresis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Electrophoresis method used for separating molecules of proteins and nucleic acids from a sample mixture of similar molecules through a gelatinous matrix. Subject to an electric field, each molecule in the sample mixture migrates through the matrix at a different rate, depending mainly on electrical charge and size, resulting in spatial separation within the matrix of each molecular species in the sample mixture. Agarose and acrylamide in a cylindrical tube or slab gel are commonly used media for electrophoresis of proteins and nucleic acids.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gel electrophoresis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C18091 NPO_1419 gel electrophoresis agarose gel electrophoresis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Gel electrophoresis in which highly purified agar is used as the diffusion medium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>agarose gel electrophoresis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C16537 NPO_1420 agarose gel electrophoresis polyacrylamide gel electrophoresis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Gel electrophoresis technique in which a polyacrylamide gel is used as the diffusion medium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polyacrylamide gel electrophoresis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C16539 NPO_1421 polyacrylamide gel electrophoresis analysis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process of examining the component parts of a whole and their relations in making up the whole [source: WordNet]. e.g., the identification and measurement of chemical constituents of a substance or specimen.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>analysis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1422 analysis protein analysis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Analysis of protein components in a sample.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>protein analysis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1423 analysis of proteins protein analysis western blot analysis <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A technique which is used for the detection or identification of proteins or peptides that have been separated by gel electrophoresis and transferred onto nitrocellulose or other type of paper or nylon membrane. The proteins are then detected by reaction with enzymatically labeled or radiolabeled antibody probes.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>western blot analysis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C16357 NPO_1424 western blot western blot analysis western blotting western blotting technique detection <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process or action of identifying the presence of something.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>detection</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1425 detection detection of proteins <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Detection of proteins or a protein components in a sample.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>detection of proteins</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1426 detection of proteins protein detection SDS polyacrylamide gel electrophoresis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polyacrylamide gel electrophoresis technique for separating proteins in a sample which is prepared with sodium dodecyl sulfate (SDS) as a buffer that maintains the proteins in their denatured states.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>SDS polyacrylamide gel electrophoresis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1427 SDS polyacrylamide gel electrophoresis SDS-PAGE sodium dodecyl sulfate - polyacrylamide gel electrophoresis electron microscopy <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A microscopy technique based on the use of electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>electron microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1428 electron microscopy scanning electron microscopy <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electron microscopy technique based on the use of scanning electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>scanning electron microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1429 SEM technique scanning electron microscopy transmission electron microscopy <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electron microscopy technique based on the use of transmission electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>transmission electron microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> A light source at the top of the TEM emits the electrons that travel through vacuum in the column of the microscope. Instead of glass lenses focusing the light in the light microscope, the TEM uses electromagnetic lenses to focus the electrons into a very thin beam. The electron beam then travels through the specimen you want to study. Depending on the density of the material present, some of the electrons are scattered and disappear from the beam. At the bottom of the microscope the unscattered electrons hit a fluorescent screen, which gives rise to a shadow image of the specimen with its different parts displayed in varied darkness according to their density. The image can be studied directly by the operator or photographed with a camera. [source: http://Nobelprize.org] NPO_1430 TEM technique transmission electron microscopy optical microscopy <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A microscopy technique based on the use of optical microscope.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>optical microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1431 light microscopy optical microscopy fluorescence microscopy <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An optical microscopy technique based on the use of fluorescence microscope.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluorescence microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1432 fluorescence microscopy scanning probe microscopy <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A microscopy technique based on the use of scanning probe microscope.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>scanning probe microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C20346 NPO_1433 scanning probe microscopy atomic force microscopy <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scanning probe microscopy technique based on the use of atomic force microscope.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>atomic force microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1434 atomic force microscopy scanning force microscopy scanning tunneling microscopy <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scanning probe microscopy technique based on the use of scanning tunneling microscope.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>scanning tunneling microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1435 scanning tunneling microscopy instrument <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A device or tool that requires skill for proper use, and it is intended for a purpose.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>instrument</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1436 equipment instrument microscope <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An instrument which is used for magnifying and viewing images of objects that are too small to be seen by the naked or unaided eye. [source:http://encyclopedia.thefreedictionary.com/microscope]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C20677 NPO_1437 microscope electron microscope <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A microscope that is similar in purpose to a light microscope but achieves much greater resolving power by using a parallel beam of electrons to illuminate the object instead of a beam of light. [source:WordNet 3.0]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>electron microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Electron Microscopes(EMs) function exactly as their optical counterparts except that they use a focused beam of electrons instead of light to "image" the specimen and gain information as to its structure and composition. The basic steps involved in all EMs: 1. A stream of electrons is formed (by the Electron Source) and accelerated toward the specimen using a positive electrical potential 2. This stream is confined and focused using metal apertures and magnetic lenses into a thin, focused, monochromatic beam. 3. This beam is focused onto the sample using a magnetic lens 4. Interactions occur inside the irradiated sample, affecting the electron beam These interactions and effects are detected and transformed into an image The above steps are carried out in all EMs regardless of type. [source: http://unl.edu/CMRAcfem/em.htm] NCIT:C28219 NPO_1438 electron microscope optical microscope <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A microscope which uses visible light and a system of lenses to magnify images of small objects.[source: http://encyclopedia.thefreedictionary.com]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>optical microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C28265 NPO_1439 light microscope optical microscope iodine atom 53 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 53.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iodine atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_144 iodine atom scanning electron microscope <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electron microscope which scans the surface of a sample with a beam of electrons and detects the interaction of the electrons with the atoms on the surface to produce a topographical image of the sample.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>scanning electron microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C78814 NPO_1440 SEM scanning electron microscope transmission electron microscope <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electron microscope which transmits a beam of electrons through a finely sliced section of a specimen/sample and creates an image of the specimen/sample based on its effect on the phase of the electrons that pass through.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>transmission electron microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C78813 NPO_1441 TEM TEMs use electrons as light source and their much lower wavelength makes it possible to get a resolution a thousand times better than with a light microscope.[source: http://Nobelprize.org] transmission electron microscope scanning probe microscope <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A microscope which forms images of surfaces using a physical probe that scans the specimen and records the probe-surface interaction as a function of position.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>scanning probe microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C78803 NPO_1442 SPM scanning probe microscope fluorescence microscope <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An optical microscope which is used to study the properties of a specimen or sample based on the phenomena of fluorescence and phosphorescence. The microscope has a filter which allows radiation of a specific wavelength of light to pass through.The specimen or the sample contains components labeled with a fluorescent molecule which absorbs this light, and then emits light of a longer wavelength. A second filter of the microscope separates the emitted light from the brighter excitation light (shorter wavelength). As a result, the fluorescing regions of the sample shine out against a dark background with high contrast, when observed through the microscope.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluorescence microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1443 [definition: adapted from http://nobelprize.org; http://en.wikipedia.org/wiki/Fluorescence_microscope ] fluorescence microscope atomic force microscope <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scanning probe microscope which consists of a microscale cantilever with a sharp tip (probe) at its end that is used to scan the specimen surface. The probe is extremely close to - but does not touch-the surface. As the probe traverses the surface, attractive and repulsive forces arising between it and the atoms on the surface induce forces on the probe that bend the cantilever. The amount of bending is measured and recorded, providing a map of the atoms on the surface. Atomic force microscopes can achieve magnification of a factor of 5 × 10^6, with a resolution of 2 angstroms, sufficient to resolve individual carbon atoms.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>atomic force microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> AFM NCIT:C78804 NPO_1445 SFM [definition: adapted from NCIT, http://www.thefreedictionary.com, http://en.wikipedia.org] atomic force microscope scanning force microscope scanning tunneling microscope <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scanning probe microscope which consists of a probe with a small voltage applied to it ending in a tiny sharp electrically conducting tip (ideally consisting of one atom) that is moved close the material's surface. It scans the surface of a sample with a beam of electrons, causing a narrow channel of tunneling electrons to flow between the sample and the beam, and producing three-dimensional images of atomic topography and structure.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>scanning tunneling microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C17374 NPO_1446 STM [definition: adapted from http://www.thefreedictionary.com] scanning tunneling microscope magnetic force microscope <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scanning probe microscope which is derived from atomic force microscope, having a magnetized tip that map the spatial distribution of magnetism by measuring the magnetic interactions between the sample and the tip. It is used to study magnetic materials.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>magnetic force microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MFM NPO_1447 [definition: adapted from http://encyclopedia.thefreedictionary.com] magnetic force microscope doxorubicin-loaded nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is loaded with doxorubicin.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>doxorubicin-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_145 adriamycin-loaded nanoparticle doxorubicin-loaded nanoparticle high resolution transmission electron microscopy <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A transmission electron microscopy technique based on the use of high resolution transmission electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>high resolution transmission electron microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1451 high resolution transmission electron microscopy high resolution transmission electron microscope <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A transmission electron microscope which operates at an imaging mode that allows the imaging of the crystallographic structure of a sample at an atomic scale. In this mode, the transmitted and the diffracted beams of electrons are allowed to interfere to produce phase-contrast images.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>high resolution transmission electron microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> HRTEM NPO_1452 [definition source]: http://en.wikipedia.org high resolution transmission electron microscope scanning transmission electron microscope <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A transmission electron microscope with which a beam of electrons pass through the specimen, where the beam is focused into a narrow spot that is scanned over the sample specimen in a raster.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>scanning transmission electron microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1453 STEM scanning transmission electron microscope scanning transmission electron microscopy <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A transmission electron microscopy technique based on the use of scanning transmission electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>scanning transmission electron microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1454 scanning transmission electron microscopy differential interference contrast microscope <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An optical microscope which generates contrast within the specimen by exploiting phase differences between a specimen (sample) light ray and a reference ray. The sample and reference rays are created after the ray traverses, and is phase-distorted by, the sample. The phased ray then is split into two equally phased, but spatially separated ("sheared") rays by the action of a Wollaston prism. Finally, the ray-pairs pass through a polarizing filter where they are vibrationally recombined and interact at the image plane. It is the wave interference of these two rays that creates contrast.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>differential interference contrast microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DIC microscope DIC microscope is based on interferometry, which is the technique of superposing (interfering) two or more waves, to detect differences between them. In interferometry, a single ray of light is split into two rays, one traversing and the other missing the specimen but interacting with the background. The rays are then recombined at the image plane, where wave interference may occur. Image contrast can be modified by altering the phase difference between the reference and specimen rays. [source: http://encyclopedia.thefreedictionary.com] NPO_1455 differential interference contrast microscope differential interference contrast microscopy <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An optical microscopy based on the use of differential interference contrast microscope.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>differential interference contrast microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1456 differential interference contrast microscopy nanoparticle response to external stimulus <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to stimulus, which occurs in response to the external stimulus acting on the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to external stimulus</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_146 nanoparticle response to external stimulus flow cytometry <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A technique for counting, examining and sorting microscopic particles (e.g., single cells) suspended in a stream of fluid that passes through a beam of light. It allows for multiple analyses of the physical and chemical characteristics of single cells flowing through an optical and/or electrical detection apparatus.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>flow cytometry</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C16585 NPO_1465 [definition: adapted from NCIT, http://encyclopedia.thefreedictionary.com] flow cytometry phase analysis light scattering <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A light scattering technique for measuring the electrophoretic mobilities of charged particles suspended in nonpolar media (i.e. solvents with much lower relative permittivities than water).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>phase analysis light scattering</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1467 PALS [definition: adapted from http://www.unisa.edu.au/laser/Research/PALS.asp] phase analysis light scattering spectroscopy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A technique which is used for measuring the intensity of electromagnetic radiation that is absorbed, emitted (radiated), or scattered at different wavelengths or frequencies by a molecular entity or substance. This technique is used in studying the interaction of electromagnetic radiation with matter.</ncicp:def-definition><ncicp:Definition_Review_Date>100611</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C17155 NPO_1468 spectroscopic technique spectroscopy dynamic light scattering <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A spectroscopic technique which utilizes a laser beam to irradiate a sample containing particles in suspension, resulting in light scattering.When the scattered light is collected over a small solid angle, the light will exhibit intensity fluctuations. This is because the Brownian motion of the scatterers causes the phase of the light scattered from each particle to change with time, hence the total scattered intensity also fluctuates with time. The rapid fluctuations in scattering intensity, collected around a mean value at a certain angle, will depend on the particle diffusion and on the particle size. For a given temperature and viscosity, a calculated correlation function yields a diffusion coefficient, which can be used to calculate particle size.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dynamic light scattering</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DLS NCIT:C62329 NPO_1469 PCS QELS Quasi-Elastic Light Scattering [definition source: NCI] dynamic light scattering photon correlation spectroscopy compound or molecule <ncicp:ComplexDefinition><ncicp:def-definition>A pure substance which is made up of more than one type of atom, and can be decomposed into its elements by chemical methods. This class includes terms that can be used to describe molecules or compounds. A molecule is a group of atoms bonded together, representing the smallest fundamental unit of a chemical compound that can take part in a chemical reaction.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>compound or molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_147 compound or molecule nuclear magnetic resonance spectroscopy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An absorption spectroscopic technique which uses NMR (nuclear magnetic resonance) to basically measure the frequency (resonant frequency) of vibrating nuclei (having non-zero spin) of a given type in the presence of a magnetic field. When placed in a magnetic field, nuclei that have non-zero spins absorb frequency characteristic of the isotope. The frequency (resonant frequency), the energy of absorption, and the intensity of measured NMR signal are proportional to the strength of the magnetic field. Nuclei of different isotopes in a substance resonate at different frequencies depending upon the local molecular geometry (bond lengths, bond angles, bonded atoms, etc.) and the local magnetic field at each nucleus. Nuclei of the same type can have slightly different resonant frequencies depending on the chemical environment. The difference between the frequency of the measured signal (NMR signal) from nuclei (in a molecule) in one sample and that (reference resonant frequency) from the same type of nuclei in a reference substance is used to obtain structural information of the molecule in a sample, or the chemical composition of the sample. This technique has applications in the study of the physical, chemical, and biological properties of matter.</ncicp:def-definition><ncicp:Definition_Review_Date>100610</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.answers.com/topic/nmr-spectroscopy (June 10, 2010), http://www.cis.rit.edu/htbooks/nmr/inside.htm (June 10, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nuclear magnetic resonance spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Depending on the local chemical environment, different protons in a molecule resonate at slightly different frequencies. Since this frequency shift is proportional to the strength of the magnetic field, it is converted into a field-independent dimensionless value known as the chemical shift. The chemical shift is reported as a relative measure from some reference resonance frequency. (For the nuclei1H, 13C, and 29Si, TMS (tetramethylsilane) is commonly used as a reference.) This difference between the frequency of the signal and the frequency of the reference is divided by frequency of the reference signal to give the chemical shift. The frequency shifts are extremely small in comparison to the fundamental NMR frequency. A typical frequency shift might be 100 Hz, compared to a fundamental NMR frequency of 100 MHz, so the chemical shift is generally expressed in parts per million (ppm). By understanding different chemical environments, the chemical shift can be used to obtain some structural information about the molecule in a sample. The conversion of the raw data to this information is called assigning the spectrum. [source: http://encyclopedia.thefreedictionary.com] NCIT:C16810 NMR spectroscopy NPO_1470 When placed in a magnetic field, NMR active nuclei (such as 1H or 13C) absorb at a frequency characteristic of the isotope. The resonant frequency, energy of the absorption and the intensity of the signal are proportional to the strength of the magnetic field. magnetic resonance spectroscopy nuclear magnetic resonance spectroscopy fluorescence spectroscopy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which analyzes fluorescence spectra from a sample. It involves using a beam of light, usually ultraviolet light, that excites the electrons in molecules of certain compounds and causes them to emit light of a lower energy, typically, but not necessarily, visible light.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluorescence spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C17738 NPO_1476 fluorescence spectroscopy fluorometry spectrofluorometry imaging technique <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A technique to obtain the image (appearance or form) of the whole or part of a material object.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>imaging technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C17369 NPO_1477 imaging method imaging technique diagnostic imaging <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Imaging of structural or functional patterns of organs or tissues for the purpose of diagnostic evaluation.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>diagnostic imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C16502 NPO_1478 diagnostic imaging tomography <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imaging technique in which waves of energy are passed through the sections of a solid object to obtain images of the internal structures of the object.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tomography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1479 tomography non-ionizable <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A qualitative measure of "ionizability" which indicates that the bearer cannot be ionized to gain negative or positive charges.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>non-ionizable</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_148 non-ionizable computed tomography <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A medical tomographic technique which uses computer to construct a three-dimensional image of the internal structures of an object from a large series of two-dimensional cross-sectional X-ray images of the object, taken around a single axis of rotation.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>computed tomography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CT NCIT:C17204 NPO_1480 computed tomography single photon emission computed tomography <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A tomographic technique which uses radionuclides that emit single photons in the gamma energy range. The radionuclides are administered into a patient's body and the gamma rays produced by these radionuclides pass through the patient's body, which are then detected by one or more gamma cameras rotated around the patient's body. Series of two-dimensional cross-sectional images of the body, produced by this technique, can be used to create three-dimensional images by computer reconstruction.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>single photon emission computed tomography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C17203 NPO_1481 SPECT single photon emission computed tomography positron emission tomography <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A tomography technique for measuring the gamma radiation produced by collisions of electrons and positrons (anti-electrons) within living tissue. In positron emission tomography (PET), a subject is given a dose of a positron-emitting radionuclide attached to a metabolically active substance (for example, 2-fluoro-2-deoxy-D-glucose (FDG), which is similar to a naturally occurring sugar, glucose, with the addition of a radioactive fluorine atom). When living tissue containing the positron emitter is bombarded by electrons, gamma radiation produced by collisions of electrons and positrons is detected by a scanner, revealing in fine detail the tissue location of the metabolically-active substance administered.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>positron emission tomography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C17007 NPO_1482 PET [definition source: NCI] positron emission tomography magnetic resonance imaging <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A non-invasive imaging method of creating images of internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>magnetic resonance imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MRI MeSH:D008279 NCIT:C16809 NPO_1483 [definition: adapted from MeSH] magnetic resonance imaging ultrasound imaging <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imaging technique in which ultrasound (sound waves with frequency above the human hearing range) waves are bounced off tissues and the echoes produce a picture (sonogram).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ultrasound imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C17230 NPO_1484 ultrasound imaging titanium dioxide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of titanium consisting of two oxygen atoms bonded to one titanium atom via double bonds.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>titanium dioxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1485 TiO2 titanium dioxide titanium oxide titanium(IV) oxide titanium oxide nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle, which is basically composed of titanium dioxide.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>titanium oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1486 TiO2 nanoparticle titanium oxide nanoparticle sample <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance which is a small representative portion of a whole material entity.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sample</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1487 sample sample composition <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Chemical composition of a sample determined by the type and amount of the chemical components of a sample.</ncicp:def-definition><ncicp:Definition_Review_Date>100727</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sample composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1488 sample composition sample preparation <ncicp:ComplexDefinition><ncicp:def-definition>A process which is the synthesis or preparation of a sample for analysis, testing or characterization.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sample preparation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1489 sample preparation covalent interaction <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An intramolecular interaction in which two atoms share one or more electron pairs.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>covalent interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_149 covalent bonding covalent interaction nanoparticle property <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A property which inheres in or borne by a nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoparticle property</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1490 nanoparticle property property of nanoparticle molecular component in nanoparticle formulation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component which is identified by virtue of its molecular structure in a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molecular component in nanoparticle formulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1491 molecular component in nanoparticle formulation functionalizing role <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A role which inheres in a material entity by virtue of its ability to add/modify the properties or functions of another material entity by being associated to the latter.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>functionalizing role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1492 functionalizing role functionalizing agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component in a nanoparticle formulation which adds/modifies functional properties or function of a nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>functionalizing agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1493 functionalizing agent chemical component in nanoparticle formulation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component which is identified as part of a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chemical component in nanoparticle formulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1494 chemical component in nanoparticle formulation molecular component in nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component which is identified by virtue of its molecular structure that forms part of the basic chemical make up of a nanoparticle in a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molecular component in nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1495 molecular component in nanoparticle nanoparticle component <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component which is identified as a nanoparticle based on its structure, chemical composition or function.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoparticle component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1496 nanoparticle component chemical component <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fiat material part identified as being the chemical make up of a material entity.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chemical component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1497 chemical component monomer <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A small organic molecule which is bonded to other similar molecules to form a polymer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>monomer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1498 monomer repeat unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component which occurs as repeated units linked together in a polymer chain.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>repeat unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1499 repeat unit iridium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 77.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iridium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_150 iridium chemical substance by physical state <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material entity which exists in some physical state that is identifiable as a whole at continuum length scales.</ncicp:def-definition><ncicp:Definition_Review_Date>100727</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>substance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C45306 NPO_1500 chemical substance by physical state fluid state <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a fluid.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluid state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1501 fluid state gaseous state <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a gas.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gaseous state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1502 gaseous state vapor state <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a vapor.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>vapor state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1503 vapor state liquid state <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a liquid.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>liquid state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1504 liquid state state of mixture <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a mixture.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>state of mixture</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1505 state of mixture state of suspension <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a suspension.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>state of suspension</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1506 state of suspension colloidal state <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a colloid.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>colloidal state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1507 colloidal state state of emulsion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of an emulsion.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>state of emulsion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1508 state of emulsion gel state <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a gel.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gel state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1509 gel state californium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 98.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>californium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_151 californium state of sol <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a sol.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>state of sol</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1510 state of sol solid state <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a sold.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>solid state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1511 solid state crystalline state <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a crystal.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>crystalline state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1512 crystalline state glassy state <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a glass.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>glassy state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1513 glassy state granular state <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a granule.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>granular state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1514 granular state powdered state <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a powder.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>powdered state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1515 powdered state imaging <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process of capturing, storing, manipulating, and displaying of images.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1516 imaging study <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process which is a detailed examination, analysis, or critical inspection of a subject designed to discover facts about it.[source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>study</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C63536 NPO_1517 study pharmacokinetics study <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Pharmacological study of the process by which a drug (or drug-containing material) is absorbed, distributed, metabolized, and eliminated by the body.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>pharmacokinetics study</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> A study of what the body does to a drug or a drug-containing material (e.g., drug-loaded nanoparticle). NCIT:C49663 NPO_1518 PK Study pharmacokinetic study pharmacokinetics pharmacokinetics study pharmacological study <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Study of the characteristics, effects, and uses of drugs and their interactions with living organisms.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>pharmacological study</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1519 pharmacological study pharmacology d-block element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy d-orbitals.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>d-block element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_152 d-block element toxicology study <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Pharmacological study of the toxicity effects of a drug or drug-containing material.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>toxicology study</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1520 toxicology study pharmacokinetic property <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A property that is characteristic of the absorption, distribution, metabolism and elimination of a drug by the body.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>pharmacokinetic property</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1521 pharmacokinetic property elimination half life <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The time required for half of an exogenous substance to be removed from either the plasma or whole or part of the body.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>elimination half life</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C70915 NPO_1522 biological half life elimination half life area under the plasma concentration time curve <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The area under the curve in a plot of concentration of a drug in plasma against time</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>area under the plasma concentration time curve</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> AUC NPO_1523 area under curve area under the plasma concentration time curve volume of distribution <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The amount of drug in the body divided by its concentration in the blood.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>volume of distribution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1524 Vd volume of distribution drug clearance <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The volume of plasma from which the drug is completely removed per unit time</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>drug clearance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CI NPO_1525 clearance drug clearance elimination rate constant <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A first-order rate constant that determines the rate at which drugs are eliminated from the body.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>elimination rate constant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1526 elimination rate constant kel Cmax <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The maximum concentration of an experimental substance or drug in the plasma or a target organ after dose administration. [source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Cmax</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Cmax NCIT:C70918 NPO_1527 maximum concentration peak concentration Tmax <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The length of time it takes to reach the maximum concentration (Cmax) of an exogenous compound or drug in the plasma or a tissue after a dose is administered.[source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Tmax</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C70919 NPO_1528 Tmax time to maximum concentration time to peak concentration bioavailability <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Fraction of the administered dose which reaches the systemic circulation and is available at the site of action.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>bioavailability</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1529 bioavailability nanoparticle response to magnetic field <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to external stimulus, which occurs in response to ultrasound.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to magnetic field</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_153 nanoparticle response to magnetic field pharmacokinetic parameter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A parameter measured or calculated in a pharmacokinetic study.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>pharmacokinetic parameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1530 pharmacokinetic parameter tumor imaging <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Imaging the size, shape, surface and structural properties of tumors.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tumor imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1531 imaging of tumors tumor imaging detection of tumors <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Detection of the presence or growth of tumors in the body of a human or an animal model.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>detection of tumors</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1532 detection of tumors tumor detection therapeutic payload agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component in a nanoparticle formulation that is a bearer of imaging function and has payload agent role.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>therapeutic payload agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1533 therapeutic payload agent imaging payload agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component in a nanoparticle formulation that is a bearer of imaging function and payload agent role.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>imaging payload agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1534 imaging payload agent tumor angiogenesis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Angiogenesis which is the formation of new blood vessels that supply oxygen and nutrients to a tumor for its growth and maintenance.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tumor angiogenesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C19361 NPO_1535 tumor angiogenesis inorganic nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of inorganic molecular entities.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inorganic nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1536 inorganic nanoparticle superparamagnetic nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has superparamagnetic properties.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>superparamagnetic nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1537 superparamagnetic nanoparticle pH-sensitive polymeric nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polymeric nanoparticle which consists of molecular components that are pH-sensitive.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>pH-sensitive polymeric nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1538 pH-sensitive polymeric nanoparticle particle diameter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Diameter which inheres in a particle.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>particle diameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1539 particle diameter rhodium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 45.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>rhodium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_154 rhodium metal oxide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of metal.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>metal oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1540 metal oxide metal oxide nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of a metal oxide.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>metal oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1541 metal oxide nanoparticle zinc oxide nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of zinc oxide.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>zinc oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1542 ZnO nanoparticle zinc oxide nanoparticle zinc oxide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of zinc.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>zinc oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1543 ZnO zinc oxide copper oxide nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of copper oxide.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>copper oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1544 copper oxide nanoparticle copper oxide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of copper.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>copper oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1545 copper oxide copper (I) oxide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of copper having the chemical formula Cu2O.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>copper (I) oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Cu2O NPO_1546 copper (I) oxide cuprous oxide copper (II) oxide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of copper having the chemical formula CuO.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>copper (II) oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CuO NPO_1547 copper (II) oxide cupric oxide iron (II,III) oxide nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iron oxide nanoparticle which is basically composed of iron(II,III) oxide.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iron (II,III) oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Fe3O4 nanoparticle NPO_1548 iron (II,III) oxide nanoparticle dextran-coated iron oxide nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iron oxide nanoparticle coated with dextran.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dextran-coated iron oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1549 dextran-coated iron oxide nanoparticle iron oxide nanoparticle coated with dextran iron (III) oxide nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of iron (III) oxide.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iron (III) oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Fe2O3 nanoparticle NPO_1550 iron (III) oxide nanoparticle spherical nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has spherical shape.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>spherical nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1551 spherical nanoparticle lipid nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of lipid molecules.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lipid nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1552 lipid nanoparticle fluorescent silica nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A silica nanoparticle which has fluorescent property.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluorescent silica nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1553 fluorescent silica nanoparticle gelatin <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A colorless water-soluble glutinous protein obtained from animal tissues such as bone and skin. (source: Word Net)</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gelatin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1554 gelatin gelatin nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of gelatin.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gelatin nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1555 gelatin nanoparticle Poly(lactic-co-glycolic acid) <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A synthetic copolymer of lactic acid and glycolic acid.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Poly(lactic-co-glycolic acid)</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1556 PLGA PLGA polymer Poly(lactic-co-glycolic acid) drug targeted against protein of tumor cell PLGA nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of poly(lactic-co-glycolic acid) polymer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>PLGA nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1559 PLGA nanoparticle poly(lactic-co-glycolic acid) nanoparticle ellipsoidal shape <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape formed by the surface of a 3-dimensional object, having elliptical or circular plane sections.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ellipsoidal shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_156 ellipsoidal ellipsoidal shape fluorescent core-shell silica nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fluorescent silica nanoparticle which has a core-shell structure.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluorescent core-shell silica nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1562 fluorescent core-shell silica nanoparticle hydroxyapatite nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of hydroxyapatite.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydroxyapatite nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1568 hydroxyapatite nanoparticle gadolinium-loaded nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is loaded with gadolinium ions.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gadolinium-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1569 gadolinium-loaded nanoparticle single-walled nanotube <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanotube which consists of a single layer or sheet of hexagonal arrays of an element or molecule, rolled into a seamless cylinder with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>single-walled nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_157 single-walled nanotube gadolinium ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion of gadolinium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gadolinium ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1570 gadolinium ion chitosan-coated magnetic nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A magnetic nanoparticle which consists of a coating agent composed of chitosan.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chitosan-coated magnetic nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1571 chitosan-coated magnetic nanoparticle core-shell silica nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A silica nanoparticle which has a core-shell structure.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>core-shell silica nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1572 core-shell silica nanoparticle tumor <ncicp:ComplexDefinition><ncicp:def-definition>An abnormal mass of tissue that results from uncontrolled proliferation of cells. It performs no bodily function. It may be benign (non-cancerous) or malignant (cancerous).</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tumor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C3262 NPO_1573 neoplasm tumor solid tumor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A benign or malignant tumor arising from tissues that do not include fluid areas.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>solid tumor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C9292 NPO_1574 solid neoplasm solid tumor tumor pH <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The pH inhering in a tumor.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tumor pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1575 tumor pH intracellular pH <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of the intracellular fluid in a cell.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>intracellular pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1576 intracellular pH pHi intracellular fluid <ncicp:ComplexDefinition><ncicp:def-definition>The fluid inside cells.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>intracellular fluid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MeSH: D007424 NPO_1577 intracellular fluid extracellular fluid <ncicp:ComplexDefinition><ncicp:def-definition>The body fluid outside of cells.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>extracellular fluid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MeSH: D045604 NPO_1578 extracellular fluid intercellular fluid extracellular pH <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of the extracellular fluid.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>extracellular pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1579 extracellular pH pHe intracellular space <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The space within a cell, which contains the intracellular fluid.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>intracellular space</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MeSH:D042541 NPO_1581 intracellular space tumor extracellular pH <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of the extracellular fluid in a tumor.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tumor extracellular pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1582 tumor extracellular pH tumor extracellular space <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Extracellular space in a tumor, which contains the tumor extracellular fluid.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tumor extracellular space</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1583 extracellular space in tumor extracellular space of tumor tumor extracellular space tumor cell <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Cell of, or derived from, a tumor.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tumor cell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1584 tumor cell intracellular fluid in a tumor cell <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Intracellular fluid inside tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>intracellular fluid in a tumor cell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1585 intracellular fluid in a tumor cell intracellular fluid in tumor cells intracellular fluid of tumor cells tumor extracellular fluid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Extracellular fluid inside a tumor.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tumor extracellular fluid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1586 tumor extracellular fluid intracellular space of tumor cell <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Intracellular space within a tumor cell.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>intracellular space of tumor cell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1587 intracellular space of tumor cell intracellular space of tumor cells tumor intracellular pH <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of the intracellular fluid in a tumor cell.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tumor intracellular pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1588 tumor intracellular pH cirulating half life <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The time taken for the concentration of an exogenous substance in the blood plasma to reduce by 50%</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cirulating half life</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1589 circulation half life cirulating half life plasma half life thioether linkage between thiol and maleimide derivative <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thioether linkage which is formed between a thiol and a maleimide derivative, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thioether linkage between thiol and maleimide derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_159 thioether linkage between thiol and maleimide derivative long circulating half life <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A circulating half life inhering in an exogenous substance (drug, nanoparticle, imaging agent) and is exhibited when it circulates in the blood plasma for a longer time compared to a reference.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>long circulating half life</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1590 long circulating half life long circulation half-life long circulating nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a circulating half life longer than that of a reference substance.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>long circulating nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1591 long circulating nanoparticle cell surface receptor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A receptor that is localized to the plasma membrane and may have exposure to the extracellular milieu. [source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cell surface receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C17067 NPO_1592 cell surface receptor folate receptor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cell surface receptor that binds to folic acid and reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells..</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>folate receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1594 folate receptor folate-binding protein growth factor receptor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cell surface receptor which binds to extracellular polypeptide molecules triggering intracellular signaling pathways that activate various cellular responses such as cell proliferation and/or differentiation. (source:NCI)</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>growth factor receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C17664 NPO_1595 growth factor receptor fiat material part <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A material entity [npo:MaterialEntity] that is part of a material entity but is not demarcated by any physical discontinuities.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fiat material part</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1597 fiat material part fluorescence imaging <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An optical imaging technique in which images are captured based on contrast provided by the fluorescence emitted from a fluorescent molecule when excited by a light of certain wavelength.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluorescence imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1598 fluorescence imaging optical imaging <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imaging technique, which encompasses many different techniques that use light of the UV to the NIR spectral region to visualize tissue optical characteristics imparted through absorption and scattering of light, as well as emission of fluorescence. [source: abstract from book chapter " Kai Licha, Contast Agents for Optical Imaging, vol. 222/2002, Contast Agents II, 2002."]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>optical imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1599 optical imaging cadmium selenide quantum dot <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quantum dot composed of cadmium selenide.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cadmium selenide quantum dot</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CdSe quantum dot NPO_160 cadmium selenide quantum dot labeling molecule <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which is used to label a chemical entity for purposes of identification or detection.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>labeling molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1602 labeling molecule molecular label dye <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A labeling molecule or substance that is used to stain and color other material entities.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dye</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1603 dye fluorescent dye <ncicp:ComplexTerm><ncicp:term-name>fluorescent dye</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> A dye which has the property to shine or glow brightly due to fluorescence. NPO_1604 fluorescent dye dye role <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A labeling role played by a molecular entity when it is used for dyeing another material entity.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dye role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1605 dye role target <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A material entity which is targeted by another material entity during the process of targeting.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>target</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1606 target targeting <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The process of directing a material entity to another material entity at a specific location.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>targeting</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1607 targeting emulsifying role <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An agent role which inheres in a molecule or compound that causes the stabilization of or formation of an emulsion during the process of emulsification.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>emulsifying role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1608 emulsifying role emulsification <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process in which two immiscible liquids are mixed to form an emulsion.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>emulsification</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1609 emulsification drug directed against intracellular domain of membrane receptor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that crosses the tumor cell membrane and blocks the intracellular domain of a membrane receptor.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>drug directed against intracellular domain of membrane receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_161 drug directed against intracellular domain of membrane receptor phase <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance or a portion of a substance, which has uniform physical and chemical properties.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1610 phase solid phase <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phase which is in the solid state.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>solid phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1611 solid phase liquid phase <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phase which is in the liquid state.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>liquid phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1612 liquid phase gas phase <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phase which is in the gaseous state.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gas phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1613 gas phase dispersed phase <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phase which is dispersed in a colloidal system.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dispersed phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1614 dispersed phase continuous phase <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phase which is medium of dispersion for the dispersed phase in a colloid.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>continuous phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1615 continuous phase functionalization of nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process in which a nanoparticle is functionalized by linking it to a molecular entity that adds or modifies the properties or functions of the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>functionalization of nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1616 functionalization of nanoparticle core <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A fiat material part which forms the basic structure or central part of an object.</ncicp:def-definition><ncicp:Definition_Review_Date>100610</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1617 core antibiotic role <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inhibitor role borne by a molecule produced by, and obtained from, certain living cells (especially bacteria, yeasts and moulds), or an equivalent synthetic molecule, which is biostatic or biocidal at low concentrations to some other form of life, especially pathogenic or noxious organisms.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>antibiotic role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1618 antibiotic role definition based on CHEBI:22582 [antibiotic] antimetabolite role <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecule role inhering in molecule, which is structurally similar to a metabolite, which competes with it or replaces it, and so prevents or reduces its normal utilization.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>antimetabolite role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1619 antimetabolite role definition based on CHEBI:35221 [antimetabolite] Group 1 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 1 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Group 1 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Group 1 Element NPO_162 binding function <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A function inherining in a molecule that has an essential end-directed activity to bind to other molecules.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>binding function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1622 binding function DNA crosslinking <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process which involves the formation of a covalent bond between two bases on DNA. (NCI)</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>DNA crosslinking</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DNA crosslinking NCIT:C25827 NPO_1623 crosslinking of DNA alkylating function <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A function inhering in a molecule that has the end-directed activity to introduce its one or more alkyl groups to another molecule.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>alkylating function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1626 alkylating function DNA intercalator role <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular role inhering in a molecule and is realized during the reversible inclusion of the molecule (or group) between the base pairs of a DNA strand.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>DNA intercalator role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DNA intercalator role NPO_1627 DNA intercalation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>DNA binding which involves insertion by covalent linkage of a molecule into the double-stranded deoxyribonucleotide polymer between the internal purine and pyrimidine base pairs stacked one on another perpendicular to the double helix axis.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>DNA intercalation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DNA intercalation NCIT:C40492 NPO_1628 simple protein <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A protein that yields only amino acids when hydrolyzed. It does not contain a prosthetic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>simple protein</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_163 [definition source]: http://www.thefreedictionary.com, L. G. Wade Jr. Organic Chemistry 3rd Edition simple protein antagonist role <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inhibitor role inhering in a molecule that inhibits the metabolism or activity of a molecule that initiates a physiological response when combined with a receptor.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>antagonist role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1630 antagonist role inhibition of folic acid metabolism <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inhibition which involves interference with, or restraint of, the activities of enzymatic biotransforming chemical modifications of folic acid.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inhibition of folic acid metabolism</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C40643 NPO_1633 folic acid metabolism inhibition inhibition of folate metabolism inhibition of folic acid metabolism inhibition of dihydrofolate reductase activity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of dihydrofolate reductase.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inhibition of dihydrofolate reductase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1634 inhibition of dihydrofolate reductase activity germanium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 32.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>germanium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_164 germanium regulator role <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular role inhering in a molecule that causes the regulation of a process or the activity of another molecule.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>regulator role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1641 regulator role surface modification of nanoparticle <ncicp:ComplexDefinition><ncicp:def-definition>A process which is performed to modify the surface of a nanoparticle using surface modifying agents.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>surface modification of nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1642 surface modification of nanoparticle inhibition of metastasis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antitumor activity which inhibits or blocks metastasis.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inhibition of metastasis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1649 inhibition of metastasis inhibition of DNA topoisomerase type I activity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of topoisomerase type I</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inhibition of DNA topoisomerase type I activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1656 inhibition of DNA topoisomerase type I activity inhibition of DNA topoisomerase type II activity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of topoisomerase type II</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inhibition of DNA topoisomerase type II activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1657 inhibition of DNA topoisomerase type II activity inhibition of DNA topoisomerase activity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of DNA topoisomerase.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inhibition of DNA topoisomerase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1658 inhibition of DNA topoisomerase activity inhibition of thymidylate synthase activity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of thymidylate synthase.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inhibition of thymidylate synthase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1659 inhibition of thymidylate synthase activity fluorescence imaging contrast agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An optical imaging contrast agent, which is fluorescent, and provides contrast in images captured using fluorescence imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluorescence imaging contrast agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_166 contrast agent in fluorescence imaging fluorescence imaging contrast agent inhibition of protein kinase activity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of protein kinase</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inhibition of protein kinase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1660 inhibition of protein kinase activity inhibition of protein tyrosine kinase activity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of protein tyrosine kinase.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inhibition of protein tyrosine kinase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1661 inhibition of protein tyrosine kinase activity agent role <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular role inhering in a molecule that causes the occurrence of a process.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>agent role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1663 agent role mendelevium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 101.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mendelevium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_167 mendelevium parameter <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A generically dependent continuant [snap:GenericallyDependentContinuant] which is 1) a constant in the equation of a curve that can be varied to yield a family of similar curves; or 2) any factor that defines a system and determines (or limits) its performance; or 3) a quantity (such as mean or variance) that characterizes a statistical population and that can be estimated by calculations from sample data.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>WordNet</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>parameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1680 parameter wave parameter <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A parameter which characterizes a wave pattern.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>wave parameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1681 wave parameter wave amplitude <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Amplitude of a wave pattern.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>wave amplitude</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1682 wave amplitude wave frequency <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Frequency of a wave pattern</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>wave frequency</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1683 wave frequency wave speed <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Speed of a wave pattern</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>wave speed</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1684 wave speed collective quality <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a group (whole) of multiple bearers of the same or different kinds. Two or more bearers should exist together for this quality to exist. This quality derives from an individual quality common to all the bearers in the group.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>collective quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1685 collective quality individual quality <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a single bearer as a whole.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1686 individual quality general individual quality <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An individual quality which inheres in a single bearer AND NOT specific to the type of bearer AND inheres in other single bearers existing by themselves independently of each other. Therefore, this quality can inhere in more than one type of single bearers.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>general individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1687 general individual quality specific individual quality <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An individual quality which inheres in a single bearer AND specific to the type of bearer.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>specific individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1688 specific individual quality dependent general individual quality <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A general individual quality which inheres in a single bearer AND NOT specific to the type of single bearer AND the bearer needs other entities (bearers or non-bearers) to exist along with it or within it to have this quality; therefore, dependent. This quality inheres in the bearer in relation to other entities.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>dependent general individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1689 dependent general individual quality iodine <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 53.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iodine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_169 iodine independent general individual quality <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A general individual quality which inheres in a single bearer AND NOT specific to the type of single bearer AND the bearer do not need other entities (bearers or non-bearers) to exist along with it to have this quality; therefore independent.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>independent general individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1690 independent general individual quality dependent specific individual quality <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A specific individual quality which inheres in a single bearer AND specific to the type of the single bearer.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>dependent specific individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1691 dependent specific individual quality independent specific individual quality <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A specific individual quality which inheres in a single bearer AND specific to the type of the single bearer AND the bearer do not need other entities (bearers or non-bearers) to exist along with it to have this quality; therefore, independent.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>independent specific individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1692 independent specific individual quality tumor size <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Size of a tumor.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>tumor size</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1693 size of tumor tumor size particle size <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Size of a particle.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>particle size</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1694 particle size size of particle independent specific collective quality <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A specific collective quality which inheres in a group of multiple bearers AND specific only to the type of bearers in the group, AND the group does not need other entities (non-bearers) to exist along with it as a whole to bear this quality.</ncicp:def-definition><ncicp:Definition_Review_Date>101029</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>independent specific collective quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1695 independent specific collective quality dependent specific collective quality <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A specific collective quality which inheres in a group of multiple bearers, AND specific only to the type of bearers in the group, AND the group needs other bearers to exist along with it as a whole to bear this quality.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>dependent specific collective quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1696 dependent specific collective quality size distribution <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A polydispersity inhering in a collection of objects based on size.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>size distribution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1697 size distribution molecular weight distribution <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A polydispersity inhering in polymers based on molecular weight.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>molecular weight distribution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1698 molecular weight distribution particle size distribution <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A size distribution inhering in particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>particle size distribution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1699 particle size distribution coagulation assay <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An in vitro assay performed to analyze the effect of a nanoparticle formulation or other substance on plasma coagulation.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCL assay protocol - ITA-12 (v 1.0)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>coagulation assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1700 blood clotting assay blood coagulation assay coagulation assay prothrombin time assay <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A coagulation assay which is performed to measure the time it takes for the blood plasma to coagulate in a sample when the coagulation is activated by prothrombin.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>prothrombin time assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1701 PT assay prothrombin time assay thrombin time assay <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A coagulation assay which is performed to measure the time it takes for the blood plasma to coagulate when the coagulation is activated by thrombin.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>thrombin time assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1702 TCT assay TT assay thrombin assay thrombin clotting time assay thrombin time assay activated partial thromboplastin time assay <ncicp:ComplexDefinition><ncicp:def-definition>A coagulation assay which is performed to measure the time it takes for the plasma to coagulate when the coagulation is activated by partial thromboplastin.</ncicp:def-definition><ncicp:Definition_Review_Date>130524</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>activated partial thromboplastin time assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> APTT assay NPO_1703 activated partial thromboplastin time assay reptilase time assay <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A coagulation assay which is performed to measure the time taken for the plasma to coagulate in a sample when the coagulation is activated by reptilase.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>reptilase time assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1704 RT assay reptilase time assay biochemical assay <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An in vitro assay which is performed using purified or crude biochemical reagents in the absence of cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCGC assay guidelines (http://ncgc.nih.gov/guidance/glossary.html)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>biochemical assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1705 biochemical assay cell-based assay <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An in vitro assay in which the analyzed sample contains live cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCGC assay guidelines (http://www.ncgc.nih.gov/guidance/glossary.html)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cell-based assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1706 cell-based assay cytoxicity assay <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cell-based assay which is performed to test the cytotoxic effects of a nanoparticle formulation or other substance.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cytoxicity assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1707 cytoxicity assay cell viability assay <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cytotoxicity assay which is performed to study the cytoxic effects of nanoparticle formulation or other substance on cell viability.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cell viability assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1708 cell viability assay LDH release assay <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cell viability assay which is performed by assessing the activity of lactate dehydrogenase (a cytoplasmic enzyme) released into the cell culture supernatant, when the plasma membrane is damaged. LDH release is used as a marker of dead cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>LDH release assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> LDH assay LDH release assay NPO_1709 lactate dehydrogenase assay manganese atom 25 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 25.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>manganese atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_171 manganese atom absorption spectroscopy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which measures the intensity of electromagnetic radiation absorbed by a molecular entity or a substance at different wavelengths or frequencies.</ncicp:def-definition><ncicp:Definition_Review_Date>100610</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>absorption spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Absorption spectroscopy is used to determine the presence of or amount of a particular substance in a sample from its absorption spectrum. When the sample interacts with the radiating field, the sample absorbs energy, i.e. photons, and the intensity of absorption (radiation absorbed by the sample) varies as a function of frequency, and this variation is the absorption spectrum. (references: wikipedia, May 27, 2010) NPO_1710 absorption spectroscopy emission spectroscopy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which measures the intensity of electromagnetic radiation emitted by a molecular entity or a substance at different wavelengths or frequencies.</ncicp:def-definition><ncicp:Definition_Review_Date>100610</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>emission spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Emission spectroscopy is used to determine the elemental composition of a material from its emission spectrum obtained by measuring the intensity of electromagnetic radiation emitted by the atoms or molecules in the material at different wavelengths. Atoms or molecules in a material undergo transition from an excited state to a lower energy state, and during this transition, and they emit photons. Each element emits (radiates) photons at a characteristic set of discrete wavelengths according to its electronic structure. Hence, by examining these wavelengths in the emission spectrum of the material, the elemental composition of the material can be determined. They are different ways to excite the atoms. (based on source: wikipedia, May 27, 2010) NPO_1711 emission spectroscopy light scattering spectroscopy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which measures the intensity of light scattered from a substance at certain wavelengths, incident angles, and polarization angles.</ncicp:def-definition><ncicp:Definition_Review_Date>100527</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>light scattering spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1712 light scattering spectroscopy wave <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A disturbance which carries energy radiated from a source and which propagates through space (vacuum or space occupied by a medium) and time.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>wikipedia (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1713 wave electromagnetic wave <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A wave which does not require a medium to travel, and hence can travel through vacuum. The wave consists of vibrating electric and magnetic fields that move at right angles to each other and to the direction of wave motion. The electric and magnetic fields are produced by the acceleration of charged particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://library.thinkquest.org/10796/ch8/ch8.htm (June 3, 2010), http://www.physicsclassroom.com/Class/waves/u10l1c.cfm (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>electromagnetic wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> E-M wave EM wave Electromagnetic waves are characterized by any of the three physical properties: frequency, wavelength or quantum (photon) energy. Frequency of a wave is defined as the ratio of the speed of light (in vacuum) to wavelength of the wave. The quantum energy is defined as the product of the Planck's constant and the wave frequency. The range of all possible frequencies or wavelengths or energies of an electromagnetic wave is called the electromagnetic spectrum. (reference: wikipedia) NPO_1714 electromagnetic wave mechanical wave <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A wave which requires a medium (e.g., air, water, solid) to travel for transmitting energy from one location to another, with no net displacement of the particles in the medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://library.thinkquest.org/10796/ch8/ch8.htm (June 3, 2010); http://www.visionlearning.com (June 8, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mechanical wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1715 mechanical wave gamma-ray wave <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths shorter than 0.001 nm, frequencies greater than 100 EHz (1 EHz = 10^18 Hz), and energies greater than 1.24 MeV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c5 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>gamma-ray wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1716 gamma-ray wave x-ray wave <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 10 nm and 0.001 nm, frequencies between 30 PHz and 100 EHz (1 PHz - 10^15 Hz, 1 EHz = 10^18 Hz), and energies between 124 eV and 1.24 MeV. An X-ray wave has wavelength shorter than that of an ultraviolet wave and longer than that of a gamma-ray wave</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c4 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>x-ray wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1717 x-ray wave ultraviolet wave <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 400 nm and 10 nm, frequencies between 300 THz and 750 THz (1 THz = 10^12 Hz), and energies between 3.1 eV and 124 eV. An ultraviolet wave has a wavelength shorter than that of a visible light wave, but longer than that of an x-ray wave.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c4 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ultraviolet wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1718 UV wave ultraviolet wave visible light wave <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 750 nm and 400 nm, frequencies between 400 THz and 750 THz (1 THz = 10^12 Hz), and energies between 1.65 eV and 3.1 eV. A visible light wave has a wavelength longer than that of an ultraviolet wave, and shorter than that of an infrared wave.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c2 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>visible light wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1719 visible light wave infrared wave <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 1 mm and 750 nm, frequencies between 300 GHz and 40 THz (1 GHz = 10^9 Hz, 1 THz = 10^12 Hz), and energies between 0.00124 eV and 1.65 eV. An infrared wave has a wavelength longer than that of a visible light wave, and shorter than that of a microwave.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c1 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>infrared wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> IR wave NPO_1720 infrared wave far-infrared wave <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared wave which has wavelengths between 1 mm and 10 um, frequencies between 300 GHz and 30 THz (1 GHz = 10^9 Hz, 1 THz = 10^12 Hz), and energies between 0.00124 eV and 0.124 eV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>far-infrared wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> FIR wave NPO_1721 far-infrared wave mid-infrared wave <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared wave which has wavelengths between 10 um and 2.5 um, frequencies between 30 THz and 120 THz (1 THz = 10^12 Hz), and energies between 0.124 eV and 0.5 eV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mid-infrared wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MIR wave NPO_1722 mid-infrared wave near-infrared wave <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared wave which has wavelengths between 2.5 um and 750 nm, frequencies between 120 THz and 400 THz (1 THz = 10^12 Hz), and energies between 0.5 eV and 1.65 eV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>near-infrared wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NIR wave NPO_1723 near-infrared wave microwave <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 30 cm and 1 mm, frequencies between 1 GHz and 300 GHz (1 GHz = 10^9 Hz), and energies between 4.1 ueV and 1.24 meV. A microwave has a wavelength longer than that of an infrared wave, but shorter than that of a radiowave.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://physics.info/em-spectrum (June 3, 2010), wikipedia (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>microwave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1724 microwave radiowave <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths longer than 30 cm, frequencies less than 1 GHz (1 GHz = 10^9 Hz). and energies less than 4.1 ueV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>radiowave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1725 radiowave transverse wave <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A mechanical wave in which the particles of the medium move back and forth in a direction perpendicular to the direction in which the wave moves and transports energy.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>transverse wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1726 transverse wave longitudinal wave <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A mechanical wave in which particles of the medium move back and forth in a direction parallel to the direction in which the wave moves and transports energy.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>longitudinal wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1727 longitudinal wave sound wave <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A longitudinal wave which transports energy (sound energy) produced by a vibrating object through a medium in which the back and forth motions of the particles result in regions of high (compression) and low pressure (rarefactions) in the medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>sound wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1728 acoustic wave sound wave audible sound wave <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A sound wave which is transmitted through air causing a sinusoidal pressure variation in the air at a frequency within the human audible range, i.e., approximately between 20 Hz and 20 kHz.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>audible sound wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1729 audible sound wave nitrogen <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 7.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nitrogen</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_173 nitrogen ultrasound wave <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A sound wave which has frequencies above 20 kHz (upper limit of the human audible frequency range).</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ultrasound wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1730 ultrasonic wave ultrasound wave radiation <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A process in which energy emitted by a material source travels in the form of waves, rays, or sub-atomic particles, through a material medium or through vacuum, to be ultimately absorbed by another material.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1731 radiation electromagnetic radiation <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A radiation which consists of waves of energy associated with electric and magnetic fields produced by the acceleration of electric charges.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>electromagnetic radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> E-M radiation EMR NPO_1732 electromagnetic radiation gamma radiation <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies greater than 100 EHz (1 EHz = 10^18 Hz), and with wavelengths shorter than 0.001 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>gamma radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1733 gamma radiation gamma ray gamma ray radiation x-ray radiation <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies between 30 PHz and 100 EHz (1 PHz = 10^15 Hz, 1 EHz = 10^18 Hz), and with wavelengths between 10 nm and 0.001 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>x-ray radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1734 x-ray x-ray radiation ultraviolet radiation <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies between 300 THz and 750 THz (1 THz = 10^12 Hz), and with wavelengths between 400 nm and 10 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ultraviolet radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1735 UV radiation ultraviolet radiation visible light radiation <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which can be detected by the human eye, and it consists of waves with frequencies between 400 THz and 750 THz (1 THz = 10^12 Hz), and with wavelengths between 750 nm and 400 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>visible light radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1736 visible light radiation infrared radiation <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies between 300 GHz and 400 THz (1 GHz = 10^9 Hz, 1 THz = 10^12 Hz), and with wavelengths between 1 mm and 750 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>infrared radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1737 infrared radiation far-infrared radiation <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared radiation which consists of waves with frequencies between 300 GHz and 30 THz (1 GHz = 10^9 Hz, 1 THz = 10^12 Hz), and with wavelengths between 1 mm and 10 um.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>far-infrared radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> FIR radiation NPO_1738 far-infrared radiation mid-infrared radiation <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared radiation which consists of waves with frequencies between 30 THz and 120 THz (1THz = 10^12 Hz ), and with wavelengths between 10 um and 2.5 um.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mid-infrared radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MIR radiation NPO_1739 mid-infrared radiation functional group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A group which is a specific atom or group of atoms attached to the carbon backbone of an organic molecule, and it is responsible for characteristic reactions of the molecule.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>functional group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Each functional group has its characteristic reactivity, which may be modified by its position within the molecule or by the presence of other neighbouring functional groups. (source: Functional Group Chemistry by James R. Hanson and Eddie Abel, published by Wiley, John & Sons, Incorporate 2002) NPO_174 characteristic group functional group near-infrared radiation <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared radiation which consists of waves with frequencies between 120 THz and 400 THz (1 THz = 10^12 Hz), and with wavelengths between 2.5 um and 750 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>near-infrared radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NIR radiation NPO_1740 near-infrared radiation microwave radiation <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies between 1 GHz and 300 GHz (1 GHz = 10^9 Hz), and with wavelengths between 30 cm and 1 mm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>microwave radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1741 microwave radiation radiowave radiation <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies less than 1 GHz (1 GHz = 10^9 Hz), and with wavelengths longer than 30 cm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>radiowave radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1742 radiowave radiation sound radiation <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A radiation which consists of waves that transmit sound energy produced from a source, and the waves travel through a medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>sound radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1743 sound radiation ultrasound radiation <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A sound radiation which consists of waves that transmit sound energy at frequencies above 20 kHz (upper limit of the human audible frequency range)</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ultrasound radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1744 ultrasound radiation energy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity which is the capacity to do work or to exert force over a distance.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1745 energy kinetic energy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Energy associated with a moving object by virtue of its motion.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>kinetic energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1746 kinetic energy potential energy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Energy which is stored in an object, and that can be converted into some form of kinetic energy.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>potential energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1747 potential energy stored energy electrical energy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Kinetic energy which is associated with moving electrons.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>electrical energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1748 electrical energy electricity heat energy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Kinetic energy which is associated with randomly moving atoms or molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>heat energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1749 heat heat energy thermal energy arylthioether linkage between thiol and fluorobenzene derivative <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An arylthioether linkage which is formed between a thiol and a fluorobenzene derivative, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>arylthioether linkage between thiol and fluorobenzene derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_175 arylthioether linkage between thiol and fluorobenzene derivative light energy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Kinetic energy which is associated with the motion of electromagnetic waves produced by the acceleration of electric charges.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1750 electromagnetic energy light light energy infrared light energy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Light energy which is associated with the motion of infrared waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>infrared light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1751 infrared light infrared light energy far-infrared light energy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Light energy which is associated with the motion of far-infrared waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>far-infrared light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1752 far-infrared light far-infrared light energy mid-infrared light energy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Infrared light energy which is asscoated with the motion of mid-infrared waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mid-infrared light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1753 mid-infrared light mid-infrared light energy near-infrared light energy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Infrared light energy which is associated with the motion of near-infrared light waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>near-infrared light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1754 near-infrared light near-infrared light energy ultraviolet light energy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Light energy which is associated with the motion of ultraviolet waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ultraviolet light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1755 UV light ultraviolet light ultraviolet light energy visible light energy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Light energy which is associated with the motion of visible light waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>visible light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1756 visible light visible light energy sound energy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Kinetic energy which is produced by the vibrations of an object, and transported by disturbances (sound waves) traveling through a medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>sound energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1757 sound sound energy audible sound energy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Sound energy which is carried by waves (audible sound waves) traveling at frequencies (between 20 Hz and 20 kHz) that can be detected by the human ear.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>audible sound energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1758 audible sound audible sound energy ultrasound energy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Sound energy which is carried by waves (ultrasound waves) that travel at frequencies above the human audible range (above 20 kHz).</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ultrasound energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1759 ultrasonic sound ultrasound ultrasound energy stimulus of near-infrared light <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by near-infrared light.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>stimulus of near-infrared light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_176 stimulus of near-infrared light chemical energy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Potential energy which is stored in the chemical bonds of molecules, and which is released as heat energy in a chemical reaction.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>chemical energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1760 chemical energy nuclear energy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Potential energy which is stored in interactions between the particles in the atomic nucleus.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>nuclear energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1761 nuclear energy cell counting technique <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A technique which is used for counting cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cell counting technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1762 cell counting technique fluorescent cell counting technique <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cell counting technique which uses fluorescence for counting the cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>fluorescent cell counting technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1763 fluorescent cell counting technique confocal laser scanning microscopy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A fluorescence microscopic technique which uses scanning laser light to excite fluorescent dyes within a thick sample, such as a biofilm. The image is collected in two dimensions and several images can be combined in an image stack to produce a cross sectional image through a sample or to create a three-dimensional rendering of the sample. This technique is particularly useful for imaging the positioning of biological structures within a three-dimensional space.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.nature.com/nrd/journal/v2/n2/glossary/nrd1008_glossary.html</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>confocal laser scanning microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CLSM NPO_1764 confocal laser scanning microscopy hemocytometer <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which consists of a thick glass slide that has a chamber with a defined volume, etched with a precisely ruled grid and is used to quantify cells or cell-sized particles in suspension.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCI Thesaurus</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>hemocytometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C78807 NPO_1765 hemocytometer dynamic light scattering instrument <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to perform dynamic light scattering technique.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>dynamic light scattering instrument</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DLS instrument NPO_1766 dynamic light scattering instrument phase analysis light scattering instrument <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to perform phase analysis light scattering technique.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>phase analysis light scattering instrument</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1767 PALS instrument phase analysis light scattering instrument environmental transmission electron microscope <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A transmission electron microscope which is designed to allow the scientist to both introduce various gases into and change the temperature of the specimen/sample environment. Reactions of the sample with its environment can then be directly recorded.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:def-source>NCI</ncicp:def-source><ncicp:attr>NCIT</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>environmental transmission electron microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> EC-TEM ETEM NCIT: C78860 NPO_1768 environmental cell-transmission electron microscope environmental transmission electron microscope flow cytometer <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to count and sort microscopic particles suspended in a buffer. This instrument consists of a flow cell, at least one lamp or laser, a variable number of emission detectors or photomultipliers, a system that converts analog signals to digital, and a computer to run the system and collect and analyze the data output.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NCI</ncicp:def-source><ncicp:attr>NCIT</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>flow cytometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C78806 NPO_1769 flow cytometer series element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element whose physical and chemical characteristics vary progressively within a series.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>series element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_177 series element analytical balance <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to determine the mass of a sample with a high degree of precision.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NCI</ncicp:def-source><ncicp:attr>NCIT</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>analytical balance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C80370 NPO_1770 analytical balance coulter counter <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>An instrument which is used to measure changes in the electrical resistance of an electrolyte solution produced by suspended nonconductive particles. Changes in resistance determine both the concentraion and size distribution of the particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>coulter counter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C62330 NPO_1771 coulter counter particle count analyzer particle count and size analyzer particle counter particle size analyzer photometer <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to measure the intensity of visible light.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCIT</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>photometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C80371 NPO_1772 photometer spectrophotometer <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A photometer which measures the intensity of visible light as a function of wavelength.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spectrophotometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C62333 NPO_1773 spectrometer spectrophotometer X-ray photoelectron spectrometer <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectrometer which is used to determine the energy of photoelectrons emitted from the core orbitals of the elements within a few nm from the surface of a material, by irradiating the material surface with soft monochromatic X-rays.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>X-ray photoelectron spectrometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1774 X-ray photoelectron spectrometer zeta potential analyzer <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>An instrument which is used to measure zeta potential.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>zeta potential analyzer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1775 zeta potential analyzer capillary electrophoresis instrument <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to perform capillary electrophoresis.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>capillary electrophoresis instrument</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1776 capillary electrophoresis instrument energy dispersive spectrometer <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A spectrometer which focuss high energy electromagnetic radiation toward a sample and measures the X-rays emitted from the sample.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>energy dispersive spectrometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> EDS EDX NCIT: C78805 NPO_1777 energy dispersive X-ray spectrometer energy dispersive spectrometer gel filtration column <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is a column in which gel particles in bead form are packed to form a separation bed through which a solution containing molecules /particles and an eluant (a buffer solution) are passed for separating the molecules/particles according to differences in their sizes.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.scribd.com/doc/6941835/gel-filtration (June 16, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>gel filtration column</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1778 gel filtration column datum value <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A value which is given for a variable or parameter in a data record.</ncicp:def-definition><ncicp:Definition_Review_Date>100618</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>datum value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1779 datum value meitnerium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 109.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>meitnerium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_178 meitnerium number <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A generically dependent continuant which can be represented using different types of numerals, and which is used for counting, measuring or computing a quantity, or for identification.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>number</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1780 number symbol <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A generically dependent continuant which is used for or regarded as representing something else.</ncicp:def-definition><ncicp:Definition_Review_Date>100618</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://dictionary.reference.com/browse/symbol (June 18, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>symbol</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1781 symbol alphanumeral <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A symbol which represents a string of letters and numbers.</ncicp:def-definition><ncicp:Definition_Review_Date>100618</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>alphanumeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1782 alphanumeral numeral <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A symbol which denotes or represents a number in a language.</ncicp:def-definition><ncicp:Definition_Review_Date>100618</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1783 numeral arabic numeral <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A numeral which is one of the following: 1, 2, 3, 4, 5, 6, 7, 8, 9, and 0.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>arabic numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1784 arabic numeral english numeral <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A numeral which denotes numbers as words used in the english language.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>english numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1785 english numeral cardinal numeral <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which is basic in form, and which is used in counting and expressing how many objects are referred to. (Examples: one, two, three, one hundred, etc.)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.sil.org/linguistics/GlossaryOfLinguisticTerms/WhatIsACardinalNumeral.htm (June 21, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cardinal numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1786 cardinal numeral distributive numeral <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which expresses a group of the number specified. (examples: by the dozen, in pairs)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.sil.org/linguistics/GlossaryOfLinguisticTerms/WhatIsADistributiveNumeral.htm (June 21, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>distributive numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1787 distributive numeral multiplicative numeral <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which expresses how many fold or how many times. (Examples: once, twice, thrice, ...)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.sil.org/linguistics/GlossaryOfLinguisticTerms/WhatIsMultiplicativeNumeral.htm (June 21, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>multiplicative numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1788 multiplicative numeral ordinal numeral <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which is used to designate positions in a sequence. (Examples: first, second, third, etc.)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ordinal numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1789 ordinal numeral atom <ncicp:ComplexDefinition><ncicp:def-definition>An atom is the smallest particle that retains all the chemical properties of a given element.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_179 atom partitive numeral <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which is used to express a fraction. (Examples: one-half, one-third, etc.)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>partitive numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1790 partitive numeral alphanumeric number <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A number which is denoted by alphanumerals.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>alphanumeric number</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1791 alphanumeric number numeric number <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A number which is denoted by arabic numerals.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>numeric number</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1792 numeric number quantitative value <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A datum value which is expressed in numbers, and which is measured, assigned, or computed.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>quantitative value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1793 quantitative value qualitative value <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A datum value which is non-numerical measure or estimate of something.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>qualitative value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1794 qualitative value computed value <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value which is obtained by computations or calculations.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>computed value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1795 calculated value computed value counted value <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value which is obtained by counting.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>counted value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1796 counted value statistical measure <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A computed value which is a summary of the individual quantitative variable values for the statistical units in a specific group (study domains).</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://stats.oecd.org/glossary</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>statistical measure</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1797 statistical measure measure of variability <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A statistical measure which describes the spread in a data set of numerical values for a quantitative variable.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>measure of variability</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1798 measure of variability measure of central tendency <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A statistical measure which is a meaure of the middle or expected value of a data set.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>measure of central tendency</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1799 measure of central tendency fiat dendrimer part <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fiat part of a dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fiat dendrimer part</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_180 fiat dendrimer part mean <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of central tendency which is the sum of all the numerical values in a data set divided by the numer of numerical values.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mean</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1800 average average value mean mean value median <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of central tendency which is the middle value of a distribution of numerical values.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>median</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1801 median mode <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of central tendency which is the most frequently occurring value in a set of numerical values.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mode</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1802 mode variance <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of variability which is the average of the square of the difference between the numerical values and the mean in a data set.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>variance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1803 variance standard deviation <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of variability which is the square root of variance.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>standard deviation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1804 standard deviation measured value <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value which is measured using an instrument.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>measured value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1805 measured value temperature value <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of temperature which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100622</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>temperature value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1806 temperature value size value <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of size which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>size value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1807 size value core composition <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Composition which refers to the types and amounts of chemical components in the core of a material entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>core composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1808 core composition semiconductor <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A solid substance which has a conductivity between that of an insulator and that of a conductor.</ncicp:def-definition><ncicp:Definition_Review_Date>100622</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>semiconductor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1809 semiconductor carbonyl-reactive and sulfhydryl-reactive crosslinker <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A heterobifunctional crosslinker, which has a carbonyl-reactive group at one end and a sulfhydryl-reactive group at the other end.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carbonyl-reactive and sulfhydryl-reactive crosslinker</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_181 carbonyl-reactive and sulfhydryl-reactive crosslinker hollow <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which indicates the presence of a hole or empty space within a material entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>hollow</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1810 hollow surface composition <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Composition which refers to the types and amounts of chemical components on the surface of a material entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1811 surface composition surface charge <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electric charge which is the net charge present on the surface of a material entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1812 surface charge body weight value <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of body weight which is measured.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>body weight value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1813 body weight value pH value <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A quantitative value of pH which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>pH value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1814 pH value zeta potential value <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of zeta potential which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>zeta potential value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1815 zeta potential value percent cell viability <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of cell viability which is measured or calculated in percentage units.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>percent cell viability</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1816 percent cell viability time value <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of time which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>time value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1817 time value duration <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A temporal interval which is the time during which a process continues to occur.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>duration</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1818 duration time of exposure <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Duration in which a material entity is in contact with or exposed to something.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>time of exposure</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1819 time of exposure lawrencium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 103.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lawrencium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_182 lawrencium parts per billion <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A dimensionless concentration notation which denotes the amount of a given substance in a total amount of 1000, 000,000 regardless of the units of measure used as long as they are the same or 1 part in10^[9].</ncicp:def-definition><ncicp:Definition_Review_Date>100625</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>parts per billion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1820 parts per billion ppb 6-mercapto-hexanoic acid 6-MHA 6-mercapto-hexanoic acid 6-mercaptohexanoic acid <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A carboxylic acid which is composed of six carbon atoms and a sulfhydryl group at the sixth carbon atom.</ncicp:def-definition><ncicp:Definition_Review_Date>100625</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>6-mercapto-hexanoic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> ?-mercaptohexonic acid CHEBI:226739 NPO_1821 OC(=O)CCCCCS mean particle size <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A mean of all the individual particle size values in a collection of particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100702</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mean particle size</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1822 average particle size mean particle size coat composition <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Chemical composition of a coating layer on a material surface.</ncicp:def-definition><ncicp:Definition_Review_Date>100702</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>coat composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1823 coat composition coating composition shell composition <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Chemical composition of a material layer surrounding the core.</ncicp:def-definition><ncicp:Definition_Review_Date>100702</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>shell composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1824 shell composition test sample <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A sample which is tested for determining its physical, chemical, and functional properties in an experiment.</ncicp:def-definition><ncicp:Definition_Review_Date>100714</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>test sample</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1825 experimental sample test sample conjugated component <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical component in a nanoparticle formulation, which is a nanoparticle or a molecule that is conjugated to another nanoparticle or molecule in the same formulation.</ncicp:def-definition><ncicp:Definition_Review_Date>100714</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>conjugated component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1826 conjugated component encapsulated component <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical component in nanoparticle formulation which is a nanoparticle or a molecule that is fully enclosed within a nanoparticle's site that is fully bounded by the particle's constituting material.</ncicp:def-definition><ncicp:Definition_Review_Date>100714</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>encapsulated component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1827 encapsulated component entrapped component <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical component in nanoparticle formulation, which is a molecule or a nanoparticle that is trapped due to non-covalent interactions in a nanoparticle's site that is partially bounded by the particle's constituting material.</ncicp:def-definition><ncicp:Definition_Review_Date>100714</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>entrapped component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1828 entrapped component mean polydispersity index <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A mean value calculated from the polydispersity indices of particle or polymeric samples of the same type.</ncicp:def-definition><ncicp:Definition_Review_Date>100727</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mean polydispersity index</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1829 mean polydispersity index fiber-optic nanosensor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanosensor which is defined as a nanometer-scale measurement device that consists of a biologically or chemically sensitive layer, such as an immobilized receptor, antibody, or nucleic acid, that is covalently attached to an optical transducer. In the case of a receptor-based nanosensor, an interaction between the immobilized receptor and its substrate - the molecule it binds to - produces a perturbation that the optical transducer converts to an electrical signal via laser-induced fluorescence.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fiber-optic nanosensor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_183 fiber-optic nanosensor particle concentration <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Concentration of particles dispersed in a medium or in solution.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>particle concentration</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1830 particle concentration solute <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A substance which dissolves in another substance (solvent) to form a solution.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>solute</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1832 solute solute role <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A role inhering in a certain amount of a compound, which is realized when it is dissolved in a solvent.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>solute role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1833 solute role solvent role <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A role which inheres in a liquid compound, and it is realized when the liquid dissolves another substance (solute).</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>solvent role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1834 solvent role solution <ncicp:ComplexDefinition><ncicp:def-definition>A liquid mixture which is a homogenous mixture formed by dissolving a substance (solute) in a liquid (solvent).</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>solution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1835 solution buffer solution <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An aqueous solution which consists of a weak acid and its conjugate base or a weak base and its conjugate acid; and which resists any changes in its pH when a small amount of strong acid or base is added to it.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://en.wikipedia.org/wiki/Buffer_solution ( July 28, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>buffer solution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1836 buffer solution aqueous solution <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A solution which contains water as the solvent.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>aqueous solution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1837 aqueous solution aqueous <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which inheres in a substance by virtue of it containing water as a solvent or a medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>aqueous</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1838 aqueous buffer <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A substance which is added to an acidic or basic solution, and then modifies its pH value to a new one and then maintains that pH.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>buffer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1839 buffer einsteinium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 99.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>einsteinium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_184 einsteinium acid solution <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>An aqueous solution which contains more hydrogen ions than hydroxyl ions.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>acid solution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1840 acid solution acidic solution alkaline solution <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An aqueous solution which contains more hydroxyl ions than hydrogen ions.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>alkaline solution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1841 alkaline solution basic solution saline <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An aqueous solution of sodium chloride.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>saline</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1842 saline saline solution sodium chloride <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A salt whcih is composed of sodium and chloride ions.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>sodium chloride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1843 NaCl sodium chloride isotonic <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a solution by virtue of it having the same solute concentration as another solution.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>isotonic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1844 isotonic isotonic saline <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A saline solution which has the same NaCl concentration as blood.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>isotonic saline</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1845 isotonic saline isotonic saline solution phosphate buffer saline <ncicp:ComplexDefinition><ncicp:def-definition>An isotonic saline solution which contains phosphate buffer.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>phosphate buffer saline</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1846 PBS phosphate buffer saline phosphate buffer saline solution distilled water <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Water which has been purified by distillation.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://encyclopedia.thefreedictionary.com (July 28, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>distilled water</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1847 distilled water deionized water <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Water which has been purified by ion exchange process, and lacks cations from sodium, calcium, iron, copper and anions such as chloride and bromide.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://encyclopedia.thefreedictionary.com (July 28, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>deionized water</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1848 deionized water polydispersity index value <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of polydispersity index, which is calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>polydispersity index value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1849 PDI value polydispersity index value iodoacetyl compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iodoacetyl compound is an organic compound which is characterized by the presence of an iodoacetyl group. It has the structure R-C(=O)-CH2-I, where R denotes an organic group or hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iodoacetyl compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_185 iodoacetyl compound iodoacetyl derivative refractive index <ncicp:ComplexDefinition><ncicp:def-definition>A realizable entity, which is defined as the ratio of the speed of light in vacuum to that in a substance. It is a measure of the speed of light in the substance.</ncicp:def-definition><ncicp:Definition_Review_Date>130524</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>refractive index</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1850 index of refraction refractive index refractive index value <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of refractive index.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>refractive index value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1851 refractive index value viscosity <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity inhering in a fluid, which is defined as the fluid's resistance to flow.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>viscosity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1852 viscosity medium <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A fluid which can hold other substances in solution or in suspension.</ncicp:def-definition><ncicp:Definition_Review_Date>100729</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>medium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1853 medium aqueous medum <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A medium which contains water.</ncicp:def-definition><ncicp:Definition_Review_Date>100729</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>aqueous medum</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1854 aqueous medum solvent medium <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A medium which is used as a solvent to form a solution.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>solvent medium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1855 solvent medium suspending medium <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A liquid medium which is used to suspend particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>suspending medium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1856 dispersing medium suspending medium viscosity value <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of viscosity, which is measured or calculatd.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>viscosity value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1857 viscosity value viscosity unit <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A unit of measure, which is a standard measure of the resistance of a fluid to deformation.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>viscosity unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1858 viscosity unit pascal second <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A viscosity unit in standard international system, which is equal to 1 pascal second</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>pascal second</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> N s/m^[2] NPO_1859 Pa s kg / (m s) pascal second gold quantum dot <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quantum dot composed of gold element</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gold quantum dot</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Au quantum dot NPO_186 gold quantum dot organic core <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A core which is composed of organic molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>organic core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1860 organic core inorganic core <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A core which is composed of inorganic molecular entities.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>inorganic core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1861 inorganic core polymeric core <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An organic core which is composed of polymers.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>polymeric core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1862 polymer core polymeric core metallic core <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which is composed of one or more metals.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>metallic core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1863 metal core metallic core metal oxide core <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which is composed of metal oxide.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>metal oxide core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1864 metal oxide core silica core <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which is composed of silica (silicon dioxide).</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>silica core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1865 silica core semiconducting core <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which has semiconducting property.</ncicp:def-definition><ncicp:Definition_Review_Date>101007</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>semiconducting core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1866 semiconducting core semiconductivity <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>An electrical conductivity which is intermediate between that of an insulator and a conductor.</ncicp:def-definition><ncicp:Definition_Review_Date>101007</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>semiconductivity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1867 semiconductivity inorganic shell <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A shell which is made of inorganic material.</ncicp:def-definition><ncicp:Definition_Review_Date>101007</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>inorganic shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1868 inorganic shell organic shell <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which is made of organic material.</ncicp:def-definition><ncicp:Definition_Review_Date>101007</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>organic shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1869 organic shell sodium atom 11 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 11.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sodium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_187 sodium atom polymeric shell <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which is composed of a polymer.</ncicp:def-definition><ncicp:Definition_Review_Date>101010</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>polymeric shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1870 polymeric shell metallic shell <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which is composed of a metal or a metal-based compound.</ncicp:def-definition><ncicp:Definition_Review_Date>101010</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>metallic shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1871 metallic shell metal oxide shell <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which is composed of metal oxide.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>metal oxide shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1872 metal oxide shell silica shell <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shel which is composed of silica.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>silica shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1873 silica shell semiconductive shell <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which exhibits semiconductivity.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>semiconductive shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1874 semiconducting shell semiconductive shell superparamagnetic core <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which exhibits superparamagnetism.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>superparamagnetic core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1875 superparamagnetic core superparamagnetic iron oxide core <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A superparamagnetic core which is composed of iron oxide.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>superparamagnetic iron oxide core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1876 superparamagnetic iron oxide core cationic surface <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material boundary which is positively charged due to the presence of cations on the material boundary.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cationic surface</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1877 cationic surface anionic surface <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material boundary which is negatively charged due to the presence of anions on the material boundary.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>anionic surface</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1878 anionic surface hydrophilic surface <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material boundary which exhibits affinity towards water molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>hydrophilic surface</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1879 hydrophilic surface drug directed against tumor DNA <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug affecting the structure, function and synthesis of DNA in tumor cells</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>drug directed against tumor DNA</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_188 drug directed against tumor DNA hydrophobic surface <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material boundary which exhibits poor affinity to water molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>hydrophobic surface</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1880 hydrophobic surface surface-functionalized nanoparticle <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a molecule that is covalently attached to the surfce of the nanoparticle and that adds a functionality to the nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface-functionalized nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1881 surface-functionalized nanoparticle surface functionalizing role <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A functionalizing role which inheres in a material entity that is covalently attached to the surface of a nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface functionalizing role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1882 nanoparticle surface functionalizing role surface functionalizing role surface functionalization of nanoparticle <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A functionalization of nanoparticle which is performed on the surface of the nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface functionalization of nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1883 functionalization of nanoparticle surface surface functionalization of nanoparticle surface functionalizing agent <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A chemical component in nanoparticle formulation which is used to functionalize the surface of a nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101027</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface functionalizing agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1884 surface functionalizing agent surface modified nanoparticle <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A nanoparticle which has a surface that is chemically modified by the attachment of a small molecule or by the replacement of a surface functional group with a different type of functional group.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface modified nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1885 surface modified nanoparticle water-soluble nanoparticle <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A nanoparticle which dissolves in water.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>water-soluble nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1886 water soluble nanoparticle water-soluble nanoparticle hydrophilic coat <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A coat which has affinity to water molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>hydrophilic coat</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1887 hydrophilic coat water-soluble coat core component <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A molecular component in a nanoparticle, which forms part or whole of nanoparticle's core.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>core component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1888 core component shell component <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A molecular component in a nanoparticle, which forms part or whole of the nanoparticle's shell.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>shell component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1889 shell component lanthanum atom 57 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 57.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lanthanum atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_189 lanthanum atom coat component <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A molecular component in a nanoparticle, which forms part or whole of the coat on a nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>coat component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1890 coat component lipid monolayer <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A lipid membrane which is one (lipid) molecule thick.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>lipid monolayer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1891 lipid monolayer silver nanoparticle <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A nanoparticle which is basically composed of silver element.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>silver nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Ag nanoparticle NPO_1892 silver nanoparticle bimetallic nanoparticle <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A metal nanoparticle which is composed of two types of metals.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>bimetallic nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1893 bimetallic nanoparticle surface group <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A functional group which is located on the surface of an object (.e.g., nanoparticle).</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1894 surface group particle <ncicp:ComplexDefinition><ncicp:def-definition>A material entity which is a minute portion of matter.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>particle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1895 particle primary particle <ncicp:ComplexDefinition><ncicp:def-definition>A particle which is originally obtained from its source.</ncicp:def-definition><ncicp:Definition_Review_Date>101124</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PAS71 (draft 2.0) 2010-09-21</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>primary particle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1896 primary particle secondary particle <ncicp:ComplexDefinition><ncicp:def-definition>A particle which is composed of two or more primary particles held together by covalent bonds or by weak forces like Van der Waals forces or by simply physical entanglements.</ncicp:def-definition><ncicp:Definition_Review_Date>101124</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PAS 71 (draft 2.0) 2010-09-21</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>secondary particle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1897 secondary particle scale of measurement <ncicp:ComplexDefinition><ncicp:def-definition>A level of measureable information about a variable.</ncicp:def-definition><ncicp:Definition_Review_Date>101203</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>scale of measurement</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1898 measurement scale scale of measurement interval scale of measurement <ncicp:ComplexDefinition><ncicp:def-definition>An interval scale is a measurement scale in which a certain distance along the scale means the same thing no matter where on the scale you are, but where "0" on the scale does not represent the absence of the thing being measured.</ncicp:def-definition><ncicp:Definition_Review_Date>101203</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.statistics.com/resources/glossary/i/intscale.php (</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>interval scale of measurement</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1899 interval measurement scale interval scale interval scale of measurement g-block element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy g-orbitals.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>g-block element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_190 g-block element Celsius scale <ncicp:ComplexDefinition><ncicp:def-definition>An interval scale of measurement which provides numerical values for temperature in the range, 0 to 100, where a value of zero corresponds to the melting point of water, while a value of 100 corresponds to the boiling point of water.</ncicp:def-definition><ncicp:Definition_Review_Date>101203</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Celsius scale</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Celsius scale NPO_1900 Fahrenheit scale <ncicp:ComplexDefinition><ncicp:def-definition>An interval scale of measurement, which provides numerical values for temperature in the range, 32 to 212, where a value of 32 corresponds to the melting point of water, while a value of 100 corresponds to the boiling point of water.</ncicp:def-definition><ncicp:Definition_Review_Date>101203</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Fahrenheit scale</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Fahrenheit scale NPO_1901 Kelvin scale <ncicp:ComplexDefinition><ncicp:def-definition>A ratio scale of measurement, which provides numerical values for temperature starting from the lowest attainable value equal to zero (absolute zero).</ncicp:def-definition><ncicp:Definition_Review_Date>101206</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Kelvin scale</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Kelvin scale NPO_1902 ratio scale of measurement <ncicp:ComplexDefinition><ncicp:def-definition>A scale of measurement in which a certain distance along the scale means the same thing no matter where on the scale you are, and where "0" on the scale represents the absence of the thing being measured.</ncicp:def-definition><ncicp:Definition_Review_Date>101206</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.statistics.com/resources/glossary/r/ratioscale.php (Dec. 6, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ratio scale of measurement</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1903 ratio measurement scale ratio scale ratio scale of measurement nominal scale of measurement <ncicp:ComplexDefinition><ncicp:def-definition>A scale of measurement, which provides a list of categories to which objects can be classified. The data so classified are termed categorical data.</ncicp:def-definition><ncicp:Definition_Review_Date>101206</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.statistics.com/resources/glossary/n/nomscale.php (Dec. 6, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nominal scale of measurement</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1904 nominal measurement scale nominal scale nominal scale of measurement ordinal scale of measurement <ncicp:ComplexDefinition><ncicp:def-definition>A scale of measurement, which assigns values to objects based on their ranking with respect to one another.</ncicp:def-definition><ncicp:Definition_Review_Date>101206</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.statistics.com/resources/glossary/o/ordscale.php (Dec. 6, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ordinal scale of measurement</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1905 ordinal measurement scale ordinal scale ordinal scale of measurement logarithmic scale <ncicp:ComplexDefinition><ncicp:def-definition>An interval scale of measurement, which provides log transformed values of a measured variable.</ncicp:def-definition><ncicp:Definition_Review_Date>101206</ncicp:Definition_Review_Date><ncicp:def-source>NCI</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>logarithmic scale</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1906 logarithmic scale pH scale <ncicp:ComplexDefinition><ncicp:def-definition>A logarithmic scale which represents log (to the base 10) values of the concentration of hydrogen ions in aqueous solutions.</ncicp:def-definition><ncicp:Definition_Review_Date>101206</ncicp:Definition_Review_Date><ncicp:def-source>NCI</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>pH scale</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1907 pH scale nanoscale <ncicp:ComplexDefinition><ncicp:def-definition>An interval scale of measurement which provides a range of values between 1 nm and a few hundred nm.</ncicp:def-definition><ncicp:Definition_Review_Date>110104</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoscale</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1908 nanoscale engineered nanomaterial <ncicp:ComplexDefinition><ncicp:def-definition>A nanomaterial which is designed for a specific purpose or function.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>ISO/TS 80004-1</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>engineered nanomaterial</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1909 engineered nanomaterial biodegradable <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition which inheres in a material entity that can be decomposed by living organisms.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>biodegradable</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_191 biodegradable e.g., biodegradable nanoparticle nanostructured material <ncicp:ComplexDefinition><ncicp:def-definition>A nanomaterial which has an internal nanostructure or surface nanostructure.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>ISO/TS 80004-1</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanostructured material</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1910 nanostructured material MTT assay <ncicp:ComplexDefinition><ncicp:def-definition>defintion</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>MTT assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MTT assay MTT cytoxicity assay NPO_1911 size assay <ncicp:ComplexDefinition><ncicp:def-definition>A physical assay which is used to measure the size of a particle or molecule.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>size assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1912 size assay dendrimer generation <ncicp:ComplexDefinition><ncicp:def-definition>The generation number of a dendrimer.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dendrimer generation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1913 dendrimer generation generation number hydrodynamic size <ncicp:ComplexDefinition><ncicp:def-definition>The size of a particle or molecule in an aqueous solution.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrodynamic size</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1914 hydrodynamic size hydrodynamic diameter <ncicp:ComplexDefinition><ncicp:def-definition>The hydrodynamic size which is the diameter of a particle or molecule (approximated as a sphere) in an aqueous solution.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrodynamic diameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1915 hydrodynamic diameter z-average <ncicp:ComplexDefinition><ncicp:def-definition>definition to be added</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>z-average</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1916 z-average diaminobutane <ncicp:ComplexDefinition><ncicp:def-definition>definition to be added</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>diaminobutane</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1917 diaminobutane tris(hydroxymethyl)aminomethane <ncicp:ComplexDefinition><ncicp:def-definition>definition to be added.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tris(hydroxymethyl)aminomethane</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1918 tris(hydroxymethyl)aminomethane poly(amidoamine) <ncicp:ComplexDefinition><ncicp:def-definition>definition to be added.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>poly(amidoamine)</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1919 poly(amidoamine) protein role <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular role inhering in a protein molecule by virtue of the protein's function.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>protein role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_192 protein role magnevist <ncicp:ComplexDefinition><ncicp:def-definition>definition to be entered.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>magnevist</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1920 magnevist material synthesis technique <ncicp:ComplexDefinition><ncicp:def-definition>A technique which describes the way how a material is synthesized.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>material synthesis technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1921 material synthesis technique method of synthesis synthesis method synthesis technique solution-based chemistry technique <ncicp:ComplexDefinition><ncicp:def-definition>A material synthesis technique in which chemical reactions require the use of a solution.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>solution-based chemistry technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1922 solution based chemistry method solution-based chemistry solution-based chemistry technique hydrothermal method <ncicp:ComplexDefinition><ncicp:def-definition>A solution-based chemistry technique in which substances are crystallized from high temperature aqueous solutions at high vapor pressures.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://en.wikipedia.org/wiki/Hydrothermal_synthesis</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrothermal method</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1923 hydrothermal method hydrothermal technique micro-emulsion method <ncicp:ComplexDefinition><ncicp:def-definition>A solution-based chemistry technique for dispersing two or more immiscible liquids as micron-sized droplets by shaking, stirring or homogenising the mixture.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.rsc.org/publishing/journals/prospect/ontology.asp?id=CMO:0.0002150$MSID=b916837k</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>micro-emulsion method</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1924 micro-emulsion method micro-emulsion technique sol-gel chemical process <ncicp:ComplexDefinition><ncicp:def-definition>A solution-based chemical technique which ...[To be completed]</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sol-gel chemical process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1925 sol-gel chemical process solvent displacement method <ncicp:ComplexDefinition><ncicp:def-definition>definition [to do]</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>solvent displacement method</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1926 solvent displacement method sonochemical method <ncicp:ComplexDefinition><ncicp:def-definition>definition [to do]</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sonochemical method</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1927 sonochemical method template-assisted solution-based synthesis <ncicp:ComplexDefinition><ncicp:def-definition>definition [to do]</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>template-assisted solution-based synthesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1928 template-assisted solution-based synthesis thin film deposition technique <ncicp:ComplexDefinition><ncicp:def-definition>A synthesis technique which involves the layer-by-layer deposition of individual atoms from a material source (solid, liquid, vapor or gas), onto the surface of a material (substrate).</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thin film deposition technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1929 thin film deposition technique zinc sulfide quantum dot <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quantum dot composed of zinc sulfide.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>zinc sulfide quantum dot</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_193 ZnS quantum dot zinc sulfide quantum dot chemical vapor deposition <ncicp:ComplexDefinition><ncicp:def-definition>A thin film deposition technique in which one or more volatile precursors react and/or decompose on the surface of the substrate.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chemical vapor deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CVD CVD technique NPO_1930 chemical vapor deposition chemical vapor deposition technique atomic layer deposition <ncicp:ComplexDefinition><ncicp:def-definition>A chemical vapor deposition technique in which gaseous precursors chemically react with a surface in a sequential manner.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>atomic layer deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1931 atomic layer deposition atomic layer deposition technique metal-organic chemical vapor deposition <ncicp:ComplexDefinition><ncicp:def-definition>A chemical vapor deposition technique in which metal organic compounds in gas phase (at moderate pressures) react to form epitaxial layers of material on the surface of the substrate.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>metal-organic chemical vapor deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MOCVD MOVPE NPO_1932 OMVPE metal-organic chemical vapor deposition metalorganic vapor phase epitaxy organometallic vapor phase epitaxy plasma-enhanced chemical vapor deposition <ncicp:ComplexDefinition><ncicp:def-definition>A chemical vapor deposition technique in which gaseous precursors react when a plasma of the gases is created by RF (radio frequency) or DC discharge between two electrodes.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>plasma-enhanced chemical vapor deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1933 PECVD plasma-enhanced chemical vapor deposition thermal chemical vapor deposition <ncicp:ComplexDefinition><ncicp:def-definition>A chemical vapor deposition in which the substrate is heated.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thermal chemical vapor deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1934 TCVD rapid thermal CVD rapid thermal chemical vapor deposition thermal CVD thermal chemical vapor deposition physical vapor deposition <ncicp:ComplexDefinition><ncicp:def-definition>A thin film deposition technique in which atoms from the surface of a solid material are vaporized by physical methods (e.g. by bombarding the solid surface with an energetic ion beam, laser beam, or electron beam), and then transported for deposition on the surface of the substrate. The deposition process takes place in under low pressure or vacuum conditions.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>physical vapor deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1935 PVD physical vapor deposition physical vapor deposition technique pulsed laser deposition <ncicp:ComplexDefinition><ncicp:def-definition>A physical vapor deposition technique in whcih the source material is vaporized by irradiating the target surface of the source material by a pulsed laser beam.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>pulsed laser deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1936 pulsed laser deposition pulsed laser deposition technique sputter deposition <ncicp:ComplexDefinition><ncicp:def-definition>A physical vapor deposition technique in which atoms from the surface of a solid material are vaporized by bombarding the surface with energetic particles (e.g., accelerated ions).</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sputter deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1937 sputter deposition sputter deposition technique magnetron sputtering <ncicp:ComplexDefinition><ncicp:def-definition>A type of sputter deposition where a magnetron is used to direct the flow of high energy electrons for the sputtering process. A magnetron is a vacuum tube in which the electrons generated from a heated cathode flows under the control of an applied magnetic field.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>magnetron sputtering</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1938 magnetron sputtering thermal evaporation <ncicp:ComplexDefinition><ncicp:def-definition>A physical vapor deposition technique in which the source material is evaporated in vacuum, and the vaporized material condenses on the surface of the substrate.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thermal evaporation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1939 thermal evaporation thermal evaporation method thermal evaporation technique electron beam physical vapor deposition <ncicp:ComplexDefinition><ncicp:def-definition>A physical vapor deposition in which a target anode is bombarded with an electron beam given off by a charged tungsten filament under high vacuum.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://en.wikipedia.org/wiki/Electron_beam_physical_vapor_deposition</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>electron beam physical vapor deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> EBPVD NPO_1940 electron beam physical vapor deposition molecular beam epitaxy <ncicp:ComplexDefinition><ncicp:def-definition>A thermal evaporation technique in which the evaporated atoms in high or ultra-high vacuum do not interact with each other until they reach the surface of the substrate. The deposition occurs at a slow rate to allow controlled growth of a monocrystalline film on a monocrystalline substrate.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molecular beam epitaxy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1941 molecular beam epitaxy resistive heating <ncicp:ComplexDefinition><ncicp:def-definition>A thermal evaporation technique in which heat is generated using electric conductors carrying current.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>resistive heating</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1942 resistive heating RF-induction technique <ncicp:ComplexDefinition><ncicp:def-definition>A thermal evaporation technique in which the target surface of the source material is heated by an electromagnetic field induced by a RF (radio frequency) signal.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>RF-induction technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1943 RF-induction technique synthesis part <ncicp:ComplexDefinition><ncicp:def-definition>A process which is conducted or occurs during the synthesis of a material.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>synthesis part</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1944 synthesis part macroscopic synthesis part <ncicp:ComplexDefinition><ncicp:def-definition>A process which is conducted during synthesis.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>macroscopic synthesis part</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1945 macroscopic synthesis part precipitation <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>precipitation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1946 precipitation co-precipitation <ncicp:ComplexDefinition><ncicp:def-definition>A solution-based chemistry technique which enables the precipitation of soluble substances.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>co-precipitation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1947 co-precipitation purification <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>purification</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1948 purification quenching <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>quenching</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1949 quenching linkage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fiat material part formed by chemically linking or associating two or more material entities (molecular entities, groups, nanomaterials) or parts thereof by molecular forces.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_195 association chemical association linkage rinsing <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>rinsing</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1950 rinsing shaking <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>shaking</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1951 shaking vortex shaking <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>vortex shaking</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1952 vortex shaking centrifugation <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>centrifugation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1953 centrifugation cooling <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cooling</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1954 cooling dissolution <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dissolution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1955 dissolution drying <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>drying</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1956 drying freeze-drying <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>freeze-drying</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1957 freeze-drying heating <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>heating</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1958 heating homogenization <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>homogenization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1959 homogenization Group 5 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 5 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Group 5 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Group 5 Element NPO_196 vanadium group element mixing <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mixing</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1960 mixing sonication <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sonication</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1961 sonication surface coating <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>surface coating</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1962 surface coating washing <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>washing</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1963 washing microscopic synthesis part <ncicp:ComplexDefinition><ncicp:def-definition>A process which takes place during synthesis of a sample at the microscopic level.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>microscopic synthesis part</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1964 microscopic synthesis part PEGylation <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>PEGylation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1965 PEGylation agglomeration <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>agglomeration</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1966 agglomeration aggregation <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>aggregation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1967 aggregation crosslinking <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>crosslinking</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1968 crosslinking dispersion <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dispersion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1969 dispersion gold nanocage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanocage composed of gold element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gold nanocage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Gold nanocages, some 40 nanometers in diameter can be made by replacing the silver atoms of silver nanotubes. NPO_197 gold nanocage self-assembly <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>self-assembly</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1970 self-assembly biological material entity <ncicp:ComplexDefinition><ncicp:def-definition>A material entity which occurs exclusively in microorganisms, plants, animals, and human beings.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>biological material entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1971 biological material entity chemical entity <ncicp:ComplexDefinition><ncicp:def-definition>A material entity which chemical interaction</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chemical entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1972 chemical entity chemical substance <ncicp:ComplexDefinition><ncicp:def-definition>A chemical entity which can be identified based on its physical state, chemical composition or molecular structure.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chemical substance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1973 chemical substance pure substance <ncicp:ComplexDefinition><ncicp:def-definition>A chemical substance which as a constant, defined composition and cannot be separated into simpler substances by physical methods.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.teacherbridge.org/public/bhs/teachers/Dana/Matter.html</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>pure substance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1974 pure substance biological fluid <ncicp:ComplexDefinition><ncicp:def-definition>A biological material entity which is fluid-like.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>biological fluid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1975 biological fluid biological molecule <ncicp:ComplexDefinition><ncicp:def-definition>A biological material entity which is a small molecule or a macromolecule.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>biological molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1976 biological molecule compound by application <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which is identified based on its application.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>compound by application</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1977 compound by application compound by chemical composition <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which is identified based on its chemical composition.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>compound by chemical composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1978 compound by chemical composition compound for imaging <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which has specific properties that makes it useful for imaging applications.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>compound for imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1979 compound for imaging beryllium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 4.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>beryllium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_198 beryllium compound for material synthesis <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which plays a role in material synthesis.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>compound for material synthesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1980 compound for material synthesis compound for targeting <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which is used for targeting other molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>compound for targeting</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1981 compound for targeting compound for therapy <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which is used for therapeutic applications.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>compound for therapy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1982 compound for therapy journal article <ncicp:ComplexDefinition><ncicp:def-definition>To be defined</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>journal article</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1983 journal article datatype <ncicp:ComplexDefinition><ncicp:def-definition>To be defined</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>datatype</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1984 datatype string <ncicp:ComplexDefinition><ncicp:def-definition>string datatype</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>string</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1985 string integer <ncicp:ComplexDefinition><ncicp:def-definition>integer datatype</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>integer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1986 integer floating point <ncicp:ComplexDefinition><ncicp:def-definition>floating point datatype</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>floating point</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1987 floating point blood coagulation pathway <ncicp:ComplexDefinition><ncicp:def-definition>A collection of processes that leads the way for blood coagulation to take place.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>blood coagulation pathway</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1989 blood coagulation pathway nanomaterial <ncicp:ComplexDefinition><ncicp:def-definition>A chemical substance which has atleast one external dimension or internal structure or surface structure in the nanoscale size range.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>ISO/TS 80004-1</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanomaterial</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_199 [Previous definition]: A material entity which is synthesized, characterized, and which has at least one spatial size dimension distinguishable in the nanoscale (1-100 nm) range. nanomaterial intrinsic pathway of blood coagulation <ncicp:ComplexDefinition><ncicp:def-definition>To be defined.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>intrinsic pathway of blood coagulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1990 intrinsic pathway of blood coagulation extrinsic pathway of blood coagulation <ncicp:ComplexDefinition><ncicp:def-definition>To be defined.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>extrinsic pathway of blood coagulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1991 extrinsic pathway of blood coagulation final common pathway of blood coagulation <ncicp:ComplexDefinition><ncicp:def-definition>To be defined.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>final common pathway of blood coagulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1992 final common pathway of blood coagulation blood coagulation time <ncicp:ComplexDefinition><ncicp:def-definition>Time needed for blood coagulation to occur.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>blood coagulation time</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1993 blood coagulation time activated partial thromboplastin time <ncicp:ComplexDefinition><ncicp:def-definition>To be defined.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>activated partial thromboplastin time</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> APTT NPO_1994 activated partial thromboplastin time prothrombin time <ncicp:ComplexDefinition><ncicp:def-definition>To be defined.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>prothrombin time</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1995 PT prothrombin time thrombin time <ncicp:ComplexDefinition><ncicp:def-definition>To be defined.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thrombin time</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1996 TT thrombin time coagulometer <ncicp:ComplexDefinition><ncicp:def-definition>an instrument which is used to measure the time required for a sample of fluid (blood) to coagulate.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>coagulometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1997 coagulometer biological specimen <ncicp:ComplexDefinition><ncicp:def-definition>A biological material entity that is analyzed in a bioassay.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>biological specimen</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1998 biological specimen biospecimen centrifuge <ncicp:ComplexDefinition><ncicp:def-definition>An instrument which is a machine that uses centrifugal force to separate substances of different densities or to remove moisture.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.merriam-webster.com (last accessed: November 6, 2011)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>centrifuge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1999 centrifuge pH-sensitive <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition, inhering in any material entity, whose structure or function can be altered by changes in pH of the medium containing it.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>pH-sensitive</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_200 pH-sensitive sensitive to pH Change incubation <ncicp:ComplexDefinition><ncicp:def-definition>A technique used for incubating mixtures in an assay.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>incubation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_2000 incubation DNA topoisomerase type I activity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>DNA topoisomerase type I activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DNA topoisomerase type I activity NPO_203 francium atom 87 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 87.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>francium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_205 francium atom component role in nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular role which inheres specifically in a a chemical component of a nanoparticle formulation with respect to its use in the formulation of nanoparticles.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>component role in nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_206 component role in nanoparticle hydrophobic core of lipid bilayer <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The hydrophobic space within the lipid bilayer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrophobic core of lipid bilayer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_207 hydrophobic core of lipid bilayer fluorobenzene group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aryl halide group containing an aromatic benzene ring attached to one or more fluorine atoms.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluorobenzene group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_208 fluorobenzene group caesium atom 55 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 55.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>caesium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_209 caesium atom metal <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A series element which is an alkali earth metal or alkali metal or inner transition element or transition element or other metal.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>metal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_210 metal attachment <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A linkage in which two molecular entities or parts thereof are joined to form a chemically conjugated molecular entity.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>attachment</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_211 attachment chemical conjugation sulfonamide linkage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a sulfonamide group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sulfonamide linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_212 sulfonamide linkage nickel atom 28 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 28.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nickel atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_213 nickel atom material boundary <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An independent continuant which describes a 2-dimensional, inner/outer surface of a material entity. The material boundary separates a material entity in its identity from other surrounding material entities.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>material boundary</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_214 material boundary material surface surface mercury <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 80.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mercury</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_216 mercury polymer-coated nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a coating agent composed of polymer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polymer-coated nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_218 polymer-coated nanoparticle stimulus of electric field <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by electric field.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>stimulus of electric field</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_219 stimulus of electric field other non-metal <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A non-metal which is any of the following elements: carbon, nitrogen, oxygen, phosphorus, selenium, sulfur.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>other non-metal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_220 other non-metal thiocyanate group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure N#C-S-. The group is characteristic of a thiocyanate organic molecule wherein it is attached to an organic group via a single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thiocyanate group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_221 thiocyanate group fluorine atom 9 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 9.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluorine atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_222 fluorine atom hydrogen bonding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A permanent dipole-dipole interaction between a hydrogen atom of -OH or -NH part of a molecule and a small, highly electronegative atom of the other polar molecule.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrogen bonding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_223 hydrogen bonding dendrimer generation layer <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular structure which describes an interior layer, formed around the dendrimer core by the addition of dendrimer branches.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dendrimer generation layer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_224 dendrimer generation layer niobium atom 41 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 41.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>niobium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_225 niobium atom two-dimensional nano-object 2-D nano-object <ncicp:ComplexDefinition><ncicp:def-definition>A nano-object which has two external dimensions in the nanoscale (between 1 and 1000 nm) range.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>two-dimensional nano-object</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_226 two-dimensional nano-object targeting ligand <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A targeting agent, which is a ligand or small molecule that binds to larger molecules.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>targeting ligand</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_227 targeting ligand cadmium selenide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inorganic compound or molecule which is composed of cadmium and selenium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cadmium selenide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CdSe NPO_228 cadmium selenide amide group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -E(=O)-NH2 or -E(=O)-NH- or -E(=O)-N(-)-, where E could denote one of the following atoms: carbon (C), sulfur (S) or phosphorus (P). The group is characteristic of an amide compound wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>amide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_229 amide group isothiourea linkage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an isothiourea group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>isothiourea linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_231 isothiourea linkage boron <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 5.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>boron</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_233 boron succinimidyl carbonate group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group, the structure of which consists of a saturated cyclic ring made up of four carbon atoms and one nitrogen atom; and each of the two carbon atoms, adjacent to the nitrogen atom, are bonded to an oxygen atom via a double bond, while the nitrogen atom is bonded to one oxygen atom of the carbonate group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>succinimidyl carbonate group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_234 succinimidyl carbonate group DNA alkylating agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>DNA crosslinking agent, which alkylates DNA.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>DNA alkylating agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DNA alkylating agent NPO_235 antineoplastic alkylating agent carbamate ester linkage between primary amine and carbonate ester <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carbamate ester linkage which is formed between a primary amine and a carbonate ester, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carbamate ester linkage between primary amine and carbonate ester</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_236 carbamate ester linkage between primary amine and carbonate ester amidine linkage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an amidine group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>amidine linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_238 amidine linkage nanobomb <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as an explosive device.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanobomb</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> An explosive device comprised of carbon nanotubes. These nanoscale devices have desirable optical and thermal properties that can be exploited for novel cancer therapeutics. The ability to manipulate these properties facilitates a controlled, localized activation and clearance mechanism of diseased or abnormal cells. NCIT: C62367 NPO_239 nanobomb isourea linkage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an isourea group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>isourea linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_240 isourea linkage oblate spheroidal shape <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spheroidal shape, which is generated by half-revolution of an ellipse around its minor axis.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>oblate spheroidal shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_241 oblate spheroidal shape ionizable aminoacid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aminoacid which can become ionized.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ionizable aminoacid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_242 ionizable aminoacid dysprosium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 66.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dysprosium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_243 dysprosium radon <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 86.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>radon</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_244 radon outer hydrophilic surface of liposome <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Outer surface of a liposome vesicle, formed by the polar head groups of lipid molecules that compose the lipid bilayer.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>outer hydrophilic surface of liposome</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_245 outer hydrophilic surface of liposome neon atom 10 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 10.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>neon atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_246 neon atom imide linkage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an imide group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>imide linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_247 imide linkage promethium atom 61 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 61.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>promethium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_248 promethium atom magnesium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 12.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>magnesium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_249 magnesium calcium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 20.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>calcium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_251 calcium lipid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound of biological origin, which contains hydrocarbons and it is insoluble in water but soluble in non-polar solvents.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lipid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_252 [ChEBI definition]: A loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids. [NCI_Thesaurus definition]: A class of hydrocarbon-containing organic compounds. Lipids are insoluble in water but soluble in nonpolar solvents and play important roles in living organisms: these roles include functioning as energy storage molecules, serving as structural components of cell membranes, and constituting important signaling molecules. Lipids can be subdivided into 2 groups: fatty acids and glycerides. lipid protactinium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 91.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>protactinium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_253 protactinium non-metal <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A series element which is not a metal.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>non-metal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_255 non-metal topoisomerase inhibitor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Enzyme inhibitor that inhibits the enzymatic activity of topoisomerases.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>topoisomerase inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C1748 NPO_256 topoisomerase inhibitor fluorine <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 9.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluorine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_257 fluorine hydrophilic space between lipid bilayers <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The aqueous space between lipid bilayers (e.g, in a multilamellar vesicle).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrophilic space between lipid bilayers</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_260 hydrophilic space between lipid bilayers chitosan nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of chitosan</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chitosan nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_261 chitosan nanoparticle antiferromagnetic (definition source): http://dictionary.reference.com/browse/antiferromagnetic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Magnetic property exhibited in materials where the magnetic moments of adjacent atoms align in opposite directions, and this quality exists only below the Neel temperature.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>antiferromagnetic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_262 antiferromagnetic glass <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A brittle transparent solid substance with irregular atomic structure.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>glass</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_263 glass carbohydrazide group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)-N(-)-N(-)-. The group is characteristic of a carbohydrazide compound.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carbohydrazide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_264 carbohydrazide group Group 13 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 13 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Group 13 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Group 13 Element NPO_266 boron group element neodymium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 60.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>neodymium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_267 neodymium ether group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -O-. The group is characteristic of an ether in which the oxygen atom is attached to two carbon atoms via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ether group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_268 ether group nanoshell <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A three-dimensional nanoparticle which is composed of a spherical core surrounded by a shell of a few nanometer in thickness. If the shell is made of metal particles, then it is called a metallic nanoshell (e.g. Gold nanoshell).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoshell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_270 nanoshell Group 6 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 6 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Group 6 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Group 6 Element NPO_271 chromium group element three-dimensional nano-object 3-D nano-object <ncicp:ComplexDefinition><ncicp:def-definition>A nano-object which has all three external dimensions in the nanoscale (between 1 and 1000 nm) range.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>three-dimensional nano-object</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_272 three-dimensional nano-object iron oxide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of iron.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iron oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_273 iron oxide shape <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Quality which exactly or approximately describes the external form or outline of something as distinct from its substance.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_274 The spatial arrangement of something as distinct from its substance. [source: NCI, WordNet] shape caesium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 55.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>caesium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_275 caesium aromatic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a chemical substance due to the presence of a cyclically conjugated molecular entity , with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>aromatic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Definition of aromatic is based on that of an aromatic compound (CHEBI:33655) NPO_276 [definition source]: ChEBI aromatic mercury atom 80 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 80.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mercury atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_277 mercury atom secondary amine linkage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a secondary amine group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>secondary amine linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_278 secondary amine linkage dendrimer core <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The core part of a dendrimer, which is formed by the core initiator group [npo:NPO_803].</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dendrimer core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_279 dendrimer core Group 14 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 14 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Group 14 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Group 14 Element NPO_280 carbon group element anticancer drug role <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role of a molecular entity, which brings about an end therapeutic result in cancer therapy.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>anticancer drug role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_281 anticancer drug role dubnium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 105.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dubnium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_282 dubnium mixture <ncicp:ComplexDefinition><ncicp:def-definition>A chemical substance which is composed of two or more substances (with variable composition) that are not chemically combined with each other and are capable of being separated hy physical means.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mixture</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_283 mixture two-dimensional nanoparticle 2-D nanoparticle <ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has two external dimensions in the nanoscale size range.</ncicp:def-definition><ncicp:Definition_Review_Date>110104</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>two-dimensional nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_284 two-dimensional nanoparticle spherical shape <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An ellipsoidal shape inhering in 3-dimensional object, where every point on the surface is equidistant from the center of the object.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spherical shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_286 spherical spherical shape gallium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 31.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gallium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_287 gallium tantalum <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 73.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tantalum</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_288 tantalum reagent <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A substance or compound, which is used to produce a chemical reaction, to detect, measure, or produce other substances; or to convert one substance into another by chemical reaction.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>reagent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_290 reagent hydrazone linkage between carbohydrazide and aldehyde <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrazone linkage which is formed between a carbohydrazide and an aldehyde, through covalent interactions between atoms of respective functional groups..</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrazone linkage between carbohydrazide and aldehyde</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_291 hydrazone linkage between carbohydrazide and aldehyde reagent role <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Role played by a substance or compound used to produce a chemical reaction to detect, measure, or produce other substances.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>reagent role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_292 obo:OBI_0000086 reagent role drug that affects protein activity related to DNA synthesis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed against a tumor cell to inhibit a protein activity related to the synthesis of DNA.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>drug that affects protein activity related to DNA synthesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_294 drug that affects protein activity related to DNA synthesis sulfonamide linkage between primary amine and sulfonyl chloride derivative <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A sulfonamide linkage which is formed between a primary amine and a suflonyl chloride derivative, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sulfonamide linkage between primary amine and sulfonyl chloride derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_295 sulfonamide linkage between primary amine and sulfonyl chloride derivative cellular uptake of extracellular material <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A biological process or mechanism by which extracellular materials are taken up by a cell.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cellular uptake of extracellular material</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_296 cellular uptake of extracellular material zinc atom 30 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 30.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>zinc atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_298 zinc atom potassium atom 19 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 19.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>potassium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_300 potassium atom double-walled carbon nanotube <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A double-walled nanotube which consists of two graphite layers or sheets of hexagonal arrays of carbon, rolled into two concentric seamless cylinders with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>double-walled carbon nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_301 double-walled carbon nanotube neptunium atom 93 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 93.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>neptunium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_304 neptunium atom chlorine atom 17 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 17.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chlorine atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_305 chlorine atom zinc sulfide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inorganic compound or molecule which is composed of zinc and sulfur.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>zinc sulfide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_306 zinc sulfide disc-shaped <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cylindrical shape inhering in 3-dimensional object with height smaller than the cross-sectional diameter.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>disc-shaped</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_307 disc-shaped disclike disk-shaped disklike anticancer drug directed against endothelial growth factor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed to affect the synthesis and function of endothelial growth factor.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>anticancer drug directed against endothelial growth factor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_308 anticancer drug directed against endothelial growth factor period element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element that has the same number of electron shells as other elements of a horizontal row in the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>period element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_310 period element amide linkage between primary amine and acid anhydride <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide linkage which is formed between a primary amine and an acid anhydride.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>amide linkage between primary amine and acid anhydride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_311 amide linkage between primary amine and acid anhydride anticancer drug <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which has the intended function to furnish pharmacological activity or other direct effect in the cure, mitigation, treatment or prevention of cancer.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>anticancer drug</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C1909 NPO_312 anticancer drug chemotherapeutic agent drug therapeutic agent intramolecular interaction <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An attractive type of chemical interaction that holds atoms together in a molecule.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>intramolecular interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_313 intramolecular interaction aluminium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 13.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>aluminium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_314 aluminium tubulin binding agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antimitotic agent, which binds to tubulin and inhibits its action.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tubulin binding agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C25974 NPO_315 tubulin binding agent hollow core of nanocapsule <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The hollow core region of a nanocapsule.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hollow core of nanocapsule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_317 hollow core of nanocapsule polonium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 84.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polonium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_318 polonium metastasis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Metastasis is the spread or migration of cancer cells from one part of the body (the organ in which it first appeared) to another. The secondary tumor contains cells that are like those in the original (primary) tumor. For example, breast cancer cells may spread (metastasize) to the lungs and cause the growth of a new tumor. When this happens, the disease is called metastatic breast cancer. (NCI)</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>metastasis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C19151 NPO_319 metastasis tumor cell migration spheroidal shape <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An ellipsoidal shape, which is generated by half-revolution of an ellipse around its major axis or minor axis.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spheroidal shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_320 spheroidal shape isocyanate group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -N=C=O. The group is characteristic of a isocyanate compounds wherein it is attached to an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>isocyanate group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_321 isocyanate group lipid membrane <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A supramolecular structure which is a membrane composed of lipid molecules.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lipid membrane</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_322 lipid membrane dubnium atom 105 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 105.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dubnium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_323 dubnium atom manganese <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 25.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>manganese</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_324 manganese contrast agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A diagnostic imaging agent, which is used during an imaging procedure to allow the delineation of biological structures in their images. Contrast agents appear opaque due to the difference in absorption of X-rays or other electromagnetic waves and surrounding tissue.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>contrast agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C390 NPO_325 contrast agent diazonium group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -[N+]#N. The group is characteristic of diazonium compounds.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>diazonium group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_326 diazonium group DNA-RNA transcription regulator <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic agent,which regulates DNA-dependent transcription.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>DNA-RNA transcription regulator</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DNA-RNA transcription regulator NPO_327 neon <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 10.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>neon</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_328 neon diazonium compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A diazonium compound is an organic compound which is characterized by the presence of a diazonium group. It has the structure R-[N+]#N, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>diazonium compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_330 diazonium compound ferrimagnetic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Magnetic property exhibited by materials in presence of an external magnetic field and in these materials the magnetic moment of the atoms on different sublattices are opposed, and the opposing magnetic moments are unequal, and therefore, a spontaneous magnetization remains. This property exists below the Curie temperature.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ferrimagnetic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_331 ferrimagnetic Lanthanide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inner transition element which is any element with atomic numbers 57 (lanthanum) to 71 (Lutetium).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Lanthanide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Lanthanide NPO_332 radium atom 88 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 88.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>radium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_333 radium atom chromium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 24.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chromium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_334 chromium uranium atom 92 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 92.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>uranium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_335 uranium atom supramolecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which is formed and held together by non-covalent interactions of molecules.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>supramolecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_337 supramolecular entity lipid bilayer <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A lipid membrane which is two (lipid) molecules thick.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lipid bilayer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MESH: D008051 NPO_338 lipid bilayer bromo group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A halo group in which the halogen atom is a bromine atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>bromo group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_339 bromo group imidoester compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imidoester compound is an organic compound which is characterized by the presence of an imidoester group. It has the structure R-C(=[NH2]+)-O-CH3, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>imidoester compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_340 imidoester compound zirconium atom 40 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 40.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>zirconium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_341 zirconium atom circular shape <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An elliptical shape in which the two foci are coincident that it is formed by a closed curve that is the path, traced by a point moving in a plane so that its distance from a fixed point (the circle's center) is a constant.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>circular shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_342 [definition based on source]:http://www.cycfoundation.org, http://www.thefreedictionary.com, NCI circular circular shape dipole-induced dipole interaction <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dipole-dipole interaction between a polar molecule and a non-polar molecule due to attraction between permanent dipole on the polar molecule and temporary dipole on the non-polar molecule; the temporary dipole on the non-polar molecule is induced by the permanent dipole on the polar molecule.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dipole-induced dipole interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> It occurs when a non-polar molecule dissolves in a polar or a dipolar solvent under the assumption that the solute dissolves because the attractive force between the solvent and solute are stronger than the intermolecular forces, holding the non-polar solute molecules together. NPO_343 dipole-induced dipole interaction aryl halide group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which consists of an aromatic ring bonded to one or more halogen atoms.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>aryl halide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_344 aryl halide group aziridine group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which consists of a nitrogen atom bonded to two adjacent carbon atoms in the form of a 3-membered saturated ring structure; it has the structure C1-C-N1. And the group is characteristic of any aziridine derivative.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>aziridine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_345 aziridine group rubidium atom 37 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 37.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>rubidium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_347 rubidium atom samarium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 62.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>samarium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_348 samarium osmium atom 76 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 76.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>osmium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_349 osmium atom rubidium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 37.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>rubidium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_350 rubidium inorganic compound or molecule <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule, in which carbon is not the principal element.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inorganic compound or molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_351 inorganic compound inorganic compound or molecule inorganic molecule mendelevium atom 101 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 101.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mendelevium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_353 mendelevium atom multi-walled carbon nanotube <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A multi-walled nanotube which consists of multiple graphite layers or sheets of hexagonal arrays of carbon, rolled in on themselves to form concentric seamless cylinders with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>multi-walled carbon nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MWCNT NPO_354 multi-walled carbon nanotube nanoparticle response to ultrasound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to external stimulus, which occurs in response to ultrasound.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to ultrasound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_356 nanoparticle response to ultrasound alpha-aminoacid sidechain <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A group that forms the sidechain of an alpha-aminoacid.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>alpha-aminoacid sidechain</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_357 alpha-aminoacid sidechain Group 4 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 4 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Group 4 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Group 4 Element NPO_358 titanium group element berkelium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 97.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>berkelium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_359 berkelium colloid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A suspension of particles (dispersed phase) in a liquid medium (dispersion medium or continuous phase).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>colloid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C32345 NPO_360 colloid core site <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A material site which is in the core of a material entity; which is hollow or a void space, into which molecular agents like drugs, imaging agents, etc. can be placed.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>core site</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_363 core site praseodymium atom 59 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 59.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>praseodymium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_366 praseodymium atom hafnium atom 72 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 72.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hafnium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_367 hafnium atom bohrium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 107.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>bohrium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_368 bohrium bismuth atom 83 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 83.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>bismuth atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_369 bismuth atom aziridine derivative <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aziridine derivative is an organic compound which is characterized by the presence of an aziridine group. It has the structure R-C1H-CH2-C1H, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>aziridine derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_370 aziridine derivative phosphorus <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 15.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>phosphorus</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_371 phosphorus linkage between primary amine and isothiocyanate <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An isothiourea linkage which is formed between a primary amine and an isothiocyanate, through covalent interactions between atoms of respective functional groups..</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>linkage between primary amine and isothiocyanate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_372 linkage between primary amine and isothiocyanate strontium atom 38 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 38.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>strontium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_374 strontium atom Group 15 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 15 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Group 15 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Group 15 Element NPO_375 pnictogen isourea linkage between primary amine and isocyanate <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An isourea linkage which is formed between a primary amine and an isocyanate, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>isourea linkage between primary amine and isocyanate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_376 isourea linkage between primary amine and isocyanate tin atom 50 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 50.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tin atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_377 tin atom rhodium atom 45 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 45.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>rhodium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_378 rhodium atom optical imaging contrast agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A contrast agent, which has optical properties, and provides contrast in images captured using optical imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>optical imaging contrast agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_379 optical imaging contrast agent gadolinium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 64.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gadolinium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_380 gadolinium ruthenium atom 44 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 44.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ruthenium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_382 ruthenium atom nanowire <ncicp:ComplexDefinition><ncicp:def-definition>A two-dimensional nano-object which has a wire-like structure made of materials that exhibit unique electrical and optical properties.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanowire</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C62376 NPO_383 nanowire holmium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 67.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>holmium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_385 holmium hydrophobic interaction <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A non-covalent interaction which is a repulsive interaction between hydrophobic molecule or hydrophobic part of an amphiphilic molecule and water molecules in aqueous solutions. It results from energetically favorable interactions between hydrophilic molecules or parts there of and water molecules.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrophobic interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_388 hydrophobic interaction arylamine linkage between primary amine and fluorobenzene derivative <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An arylamine linkage which is formed between a primary amine and a fluorobenzene derivative, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>arylamine linkage between primary amine and fluorobenzene derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_389 arylamine linkage between primary amine and fluorobenzene derivative pyrimidine antagonist <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic antimetabolite which affects the metabolism and utilization of pyrimidines.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>pyrimidine antagonist</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C1557 NPO_390 pyrimidine antagonist carboxamidine group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amidine group which has the structure -C(=N-)-NH2. It is characteristic of a carboxamidine compound.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carboxamidine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_391 carboxamidine group nanoemulsion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle formulation which exists as an emulsion and contains nanoparticles as the dispersed phase.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoemulsion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C62369 NPO_393 nanoemulsion nanoparticle emulsion imide group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide group which has the structure -C(=O)-N(-[*])-C(=O)-. The group is characteristic of an imide compound.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>imide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_394 imide group drug-loaded nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is loaded with a drug.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>drug-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_395 drug-loaded nanoparticle lawrencium atom 103 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 103.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lawrencium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_396 lawrencium atom double-walled nanotube <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanotube which consists of two layers or sheets of hexagonal arrays of an element or molecule, rolled into two concentric seamless cylinders with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>double-walled nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_398 double-walled nanotube lithium atom 3 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 3.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lithium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_400 lithium atom gold nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of gold element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gold nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Au nanoparticle NPO_401 gold nanoparticle cyanate <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cyanate is an organic compound which is characterized by the presence of a cyanate group. It has the structure R-O-C#N, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cyanate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_402 cyanate boron atom 5 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 5.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>boron atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_403 boron atom yttrium atom 39 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 39.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>yttrium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_404 yttrium atom acyl azide group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure R-C(=O)-[N+]#N, where R denotes any organic group. The group is characteristic of acyl azide compounds.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>acyl azide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_405 The structure of an acyl azide is R-C(=O)-[N+]#N, in which an acyl group is bound to a diazonium group. acyl azide group nuclear core of nanocell <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The central part of a nanocell.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nuclear core of nanocell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_407 nuclear core of nanocell f-block element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy f-orbitals.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>f-block element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_408 f-block element epidermal growth factor receptor tyrosine kinase inhibitor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Tyrosine kinase inhibitor, which inhibits Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase, involved with signal transduction pathways, and may be useful in treating tumors that over express EGFR. [source:NCI_Thesaurus]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>epidermal growth factor receptor tyrosine kinase inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> EGFR-TK inhibitor NCIT: C2167 NPO_409 epidermal growth factor receptor tyrosine kinase inhibitor polar <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in a molecule or chemical bond due to the presence of dipole moments.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polar</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_410 polar one-dimensional nano-object 1-D nano-object <ncicp:ComplexDefinition><ncicp:def-definition>A nano-object which has only one external dimension in the nanoscale (between 1 and 1000 nm) range.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>one-dimensional nano-object</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_411 one-dimensional nano-object stimulus of light <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by light.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>stimulus of light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_412 stimulus of electromagnetic radiation stimulus of light barium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 56.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>barium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_413 barium thioether linkage between thiol and acryloyl compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thioether linkage which is formed between a thiol and an acryloyl compound, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thioether linkage between thiol and acryloyl compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_414 thioether linkage between thiol and acryloyl compound hydrazone linkage between carbohydrazide and ketone <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrazone linkage which is formed between a carbohydrazide and a ketone, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrazone linkage between carbohydrazide and ketone</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_416 hydrazone linkage between carbohydrazide and ketone hydrogen atom 1 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 1.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrogen atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_418 hydrogen atom copper <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 29.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>copper</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_419 copper inner transition element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A metal which is either an actinide or a lanthanide.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inner transition element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_420 inner transition element electronegativity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity that describes the ability of an atom in a molecule to draw bonding electrons to itself.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>electronegativity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_421 [definition source]: http://hyperphysics.phy-astr.gsu.edu/Hbase/hframe.html electronegativity lead <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 51.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lead</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_424 lead rhenium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 75.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>rhenium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_425 rhenium iodo group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A halo group in which the halogen atom is a iodine atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iodo group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_426 iodo group ionizable <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A qualitative measure of "ionizability" which indicates that the bearer can be ionized to gain negative or positive charges.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ionizable</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_428 ionizable carbonate ester <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carbonate ester is an organic compound which is a diester derivative of carbonate and it is characterized by the presence of a "carbonate ester group." It has the structure R-O-C(=O)-O-R', where R, R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carbonate ester</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_429 carbonate compound carbonate ester hydrazone linkage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a hydrazone group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrazone linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_430 hydrazone linkage maleimide group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imide group derived from maleimide by the removal of a hydrogen atom that was attached to nitrogen atom of the parent maleimide. The group is characteristic of any maleimide derivative.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>maleimide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_431 maleimide group indium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 49.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>indium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_432 indium multilamellar vesicle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A liposome vesicle that has more than one lipid bilayer, and the bilayers are separated by hydrophilic spaces.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>multilamellar vesicle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_433 multilamellar vesicle thalidomide 2-(2,6-dioxopiperidin-3-yl) isoindoline-1,3-dione [source: IUPAC] <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A synthetic derivative of glutamic acid (alpha-phthalimido-glutarimide) with teratogenic, immunomodulatory, anti-inflammatory and anti-angiogenic properties. Thalidomide acts primarily by inhibiting both the production of tumor necrosis factor alpha (TNF-alpha) in stimulated peripheral monocytes and the activities of interleukins and interferons. This agent also inhibits polymorphonuclear chemotaxis and monocyte phagocytosis. In addition, thalidomide inhibits pro-angiogenic factors such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), thereby inhibiting angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thalidomide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Anticancer Drug Directed Against Endothelial Growth Factor Receptor NCIT: C870 NPO_434 thalidomide thymidylate synthase inhibitor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An enzyme inhibitor, which inhibits thymidylate synthase, an enzyme that catalyses the de novo synthesis of deoxythymidylate and acts as a key rate-limiting enzyme of DNA synthesis.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thymidylate synthase inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_435 thymidylate synthase inhibitor thymidylate synthetase inhibitor anticancer drug that modifies expression of specific genes <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed against a tumor cell to modify the expression of specific genes.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Anticancer drug that modifies expression of specific genes</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Anticancer drug that modifies expression of specific genes NPO_437 helium atom 2 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 2.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>helium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_438 helium atom silicon <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 14.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>silicon</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_439 silicon lectin inhibitor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anti-adhesion agent, which inhibits lectin, a protein that binds carbohydrate on cell surfaces and causes cell agglutination.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lectin inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C2120 NPO_440 lectin inhibitor fluorobenzene derivative <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aryl halide derived from fluorobenzene.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluorobenzene derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_441 fluorobenzene derivative enzyme inhibitor drug <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic agent, which binds to an enzyme and decreases or blocks the enzyme's activity by hindering the normal substrate-enzyme combination and the catalytic reaction.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>enzyme inhibitor drug</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MESH: D004791 NCIT: C471 NPO_442 Only those enzyme inhibitors that are used as cancer drugs should be included under this class. enzyme antagonist enzyme inhibitor enzyme inhibitor drug krypton atom 36 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 36.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>krypton atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_443 krypton atom Group 17 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 17 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Group 17 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Group 17 Element NPO_446 halogen nanopipette <ncicp:ComplexDefinition><ncicp:def-definition>A two-dimensional nano-object which is a capillary tube with diameter in the nanometer range. Nanopipettes made from standard quartz capillary tubes are known to detect single molecules which are labeled with gold nanoparticles.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanopipette</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_447 nanopipette alkali metal <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of group 1 (IUPAC style) of the periodic table: lithium (Li), sodium (Na), potassium (K), rubidium (Rb), caesium (Cs), and francium (Fr).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>alkali metal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_448 alkali metal isothiocyanate group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -N=C=S. The group is characteristic of an isothiocyanate compound wherein it is attached to an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>isothiocyanate group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_449 isothiocyanate group thioester linkage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a thioester group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thioester linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_451 thioester linkage gold nanocantilever <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanocantilever which is composed of gold.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gold nanocantilever</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_453 gold nanocantilever palladium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 46.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>palladium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_455 palladium carbamate ester linkage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a carbamate ester group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carbamate ester linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_456 carbamate ester linkage carbamate linkage nanohorn <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A two-dimensional nanoparticle which resembles a fullerene-like nanostructure and exhibits an irregular horn-like shape.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanohorn</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C62386 NPO_457 [NCI_Thesaurus definition]: A fullerene-like nanostructure that consists of graphene cylinders and exhibits an irregular horn-like shape. nanohorn ytterbium atom 70 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 70.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ytterbium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_458 ytterbium atom other metal <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A metal which is any of the following elements: aluminium, bismuth, gallium, indium, lead, hallium, tin.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>other metal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_459 other metal poor metal folate antagonist <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic antimetabolite which interferes with folic acid metabolism by inhibiting one or more folate-dependent enzymes, resulting in decreased DNA, RNA and protein synthesis. It has a chemical structure similar to folic acid, a key component in cell proliferation,</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>folate antagonist</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C511 NPO_460 antifolate folate antagonist folate inhibitor folic acid antagonist folic acid inhibitor rod-shaped <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cylindrical shape inhering in a 3-dimensional object having height greater than the cross-sectional diameter.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>rod-shaped</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C64352 NPO_461 rod-shaped rodlike Group 18 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 18 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Group 18 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Group 18 Element NPO_463 noble gas etoposide-loaded nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is loaded with etoposide.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>etoposide-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_464 etoposide-loaded nanoparticle carboxylic ester linkage between organo hydroxy compound and acid anhydride <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carboxylic ester linkage which is formed between an organo hydroxy compound and an acid anhydride, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carboxylic ester linkage between organo hydroxy compound and acid anhydride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_466 carboxylic ester linkage between organo hydroxy compound and acid anhydride samarium atom 62 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 62.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>samarium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_467 samarium atom molecular role <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role that inheres in or borne by an independent continuant at the molecular level in a particular context.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molecular role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_468 molecular role peptide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic molecule or compound, which consists of two or more amino acids linked by covalent bonding between the amino group of one aminoacid and the carboxyl group of the other.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>peptide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_469 peptide anticancer drug acting in extracellular matrix <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that acts in the extracellular matrix</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>anticancer drug acting in extracellular matrix</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_470 anticancer drug acting in extracellular matrix entrapment <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A linkage in which a molecular structure or nanostructure becomes trapped due to non-covalent interactions, in a nanoparticle's material site that is partially bounded by the particle's constituting material.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>entrapment</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_471 entrapment hollow core of nanoshell <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The hollow core of a nanoshell</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hollow core of nanoshell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_472 hollow core of nanoshell drug directed against protein of tumor cell <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed to interfere with the activity of a protein located at the tumor cell.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>drug directed against protein of tumor cell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_473 drug directed against protein of tumor cell neodymium atom 60 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 60.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>neodymium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_474 neodymium atom group element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of a group of elements in the periodic table, which have similar outer shell electronic configurations of their respective atoms.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>group element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_475 group element DNA intercalating agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A DNA binding agent that is capable of inserting itself between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>DNA intercalating agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DNA intercalating agent DNA intercalator NCIT: C582 NPO_476 stimulus of ultrasound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by ultrasound.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>stimulus of ultrasound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_477 stimulus of ultrasound Period 3 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the third row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Period 3 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_478 Period 3 Element meitnerium atom 109 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 109.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>meitnerium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_480 meitnerium atom small unilamellar vesicle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unilamellar vesicle, which has size less than 100 nm.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>small unilamellar vesicle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_481 small unilamellar vesicle gallium atom 31 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 31.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gallium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_483 gallium atom surface of micelle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Surface of a micelle formed from polar head groups of constituting amphiphilic molecules in a polar solvent.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>surface of micelle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_484 surface of micelle spacer <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A flexible molecular part that connects two other parts of the same molecule.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>spacer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_485 [definition source]: Wikipedia spacer spacer arm vanadium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 23.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>vanadium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_486 vanadium antineoplastic antimetabolite <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic agent that inhibits the biosynthesis of pyrimidine or purine nucleotides or mimic natural nucleotides so they interfere with their synthesis or function and subsequently interrupt DNA, RNA, and/or protein synthesis.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>antineoplastic antimetabolite</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MESH:D000964 NCIT:C272 NPO_487 antimetabolite antineoplastic antimetabolite darmstadtium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 110.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>darmstadtium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_488 darmstadtium solubility <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable property which inheres in a solid, liquid, or gaseous chemical substance by virtue of a certain amount of the bearer to have the ability to dissolve or not in a certain volume of a liquid solvent to form a homogeneous solution.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>solubility</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_489 PATO:0001536 solubility immunogenic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity that inheres in a material entity and indicates that the bearer has the ability to produce or elicit an immune response.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>immunogenic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_490 immunogenic ionic bonding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An intramolecular interaction between positive and negative ions which are formed by the transfer of one or more valence electrons from one atom to another atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ionic bonding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_491 ionic bonding tungsten atom 74 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 74.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tungsten atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_492 tungsten atom receptor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A protein that is located on the cell surface, or in the cytoplasm, and which binds to, or responds to, a ligand with high specificity. [based on source: UniProtKB]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C18106 NPO_493 receptor thallium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 81.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thallium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_495 thallium drug directed against protein in cytoplasm <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed to interfere with the activity of a protein located in the tumor cell cytoplasm</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>drug directed against protein in cytoplasm</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_496 drug directed against protein in cytoplasm tantalum atom 73 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 73.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tantalum atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_497 tantalum atom paramagnetic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Magnetic property exhibited in a material only when the material is kept in the presence of an externally applied magnetic field, and the magnetism disappears when the magnetic field is removed. The magnetic moments of the atoms are not aligned, and the behavior causes the material to be attracted to external magnetic fields. This behavior exists only above the Curie or Neel Temperature.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>paramagnetic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_498 paramagnetic solubility in water <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Solubility which describes the ability of a certain amount of solid, liquid or gaseous chemical substance to dissolve in a certain volume of water solvent.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>solubility in water</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_500 solubility in water water solubility antimony atom 51 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 51.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>antimony atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_501 antimony atom primary amine group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amine group which is formally derived by the removal of one hydrogen atom from ammonia, by virtue of which it has the structure -NH2. The group is characteristic of a primary amine molecule wherein it is attached to hydrocarbyl groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>primary amine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_502 primary amine group thioether linkage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a thioether group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thioether linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_504 thioether linkage acyl fluoride group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl halide group in which the halogen atom is a fluorine atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>acyl fluoride group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_505 acyl fluoride group imine linkage between primary amine and aldehyde <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imine linkage which is formed between a primary amine and an aldehyde, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>imine linkage between primary amine and aldehyde</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_507 imine linkage between primary amine and aldehyde tertiary amine group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amine group which is formally derived by the removal of three hydrogen atoms from ammonia, by virtue of which it has the structure -N(-)-. The group is characteristic of a tertiary amine molecule wherein it is attached to hydrocarbyl groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tertiary amine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_508 tertiary amine group anticancer drug directed against endothelium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed to affect the tumor endothelial cells.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>anticancer drug directed against endothelium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_509 anticancer drug directed against endothelium alpha V beta inhibitor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An endothelial-specific integrin inhibitor that acts by blocking the action of an endothelial cell-surface expressed alpha (v) integrin, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>alpha V beta inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C2050 NPO_510 alpha V beta inhibitor acyl compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl compound is an organic compound which is characterized by the presence of an acyl group R-C(=O)-, where R denotes an organic group and the carbon atom is not bonded to a hydrogen atom or oxygen atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>acyl compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_511 acyl compound curium atom 96 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 96.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>curium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_513 curium atom soluble in water <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A qualitative measure of solubility in water which indicates that the chemical substance dissolves in water under specific conditions.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>soluble in water</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_514 soluble in water water-soluble conical shape <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape formed by the surface of a 3-dimensional object that tapers from a circular base.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>conical shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_515 conical conical shape europium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 63.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>europium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_516 europium gold <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 79.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gold</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Au NPO_518 gold isocyanate compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An isocyanate is an organic compound characterized by the presence of isocyanate group. It has the structure R-N=C=O, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>isocyanate compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_519 isocyanate compound hydrogen <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 1.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrogen</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_520 hydrogen polonium atom 84 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 84.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polonium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_521 polonium atom antimony <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 51.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>antimony</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_522 antimony drug directed against extracellular domain of membrane receptor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that blocks the extracellular domain of the membrane receptor.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>drug directed against extracellular domain of membrane receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_523 drug directed against extracellular domain of membrane receptor shell of nanocapsule <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The shell of a nanocapsule.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>shell of nanocapsule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_524 shell of nanocapsule iridium atom 77 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 77.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iridium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_525 iridium atom imine linkage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an imine group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>imine linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_526 imine linkage nanoparticle response to pH change <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to internal stimulus, which occurs in response to a change in pH.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to pH change</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_528 nanoparticle response to pH change transition element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A metal which is any of the following elements: d-block element or one of the elements in groups 4, 5, 6, 10, 11, 12.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>transition element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_529 transition element maleimide derivative <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A maleimide derivative is an imide derived from maleimide by replacing the hydrogen atom bonded to nitrogen in maleimide by an organic group. It is characterized by the presence of a maleimide group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>maleimide derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_530 maleimide derivative radon atom 86 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 86.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>radon atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_531 radon atom suspension <ncicp:ComplexDefinition><ncicp:def-definition>A mixture in which fine particles are suspended in a fluid where they are supported by buoyancy.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>WordNet</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>suspension</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C45304 NPO_532 suspension roentgenium atom 111 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 111.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>roentgenium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_533 roentgenium atom astatine atom 85 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 85.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>astatine atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_534 astatine atom selenium atom 34 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 34.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>selenium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_535 selenium atom imine group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=N-)-. The group is the characteristic of an imine.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>imine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_536 imine group carbohydrate-coated nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a coating agent composed of a carbohydrate.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carbohydrate-coated nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_537 carbohydrate-coated nanoparticle dysprosium atom 66 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 66.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dysprosium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_538 dysprosium atom silicon atom 14 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 14.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>silicon atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_541 silicon atom targeting role <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role played by a molecular entity that is used to target a material entity, and the role is realized during the process of molecular targeting.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>targeting role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_542 targeting role large unilamellar vesicle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unilamellar vesicle, which has size greater than 100 nm.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>large unilamellar vesicle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_543 large unilamellar vesicle imidoester group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure C(=[NH2+])-O-CH3. The group is characteristic of an imidoester compound.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>imidoester group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_544 imidoester group anticancer drug directed against tumor cell <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug directed against a tumor cell to affect its division and function.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>anticancer drug directed against tumor cell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_549 anticancer drug directed against tumor cell gold quantum dot-entrapped poly(amidoamine) dendrimer nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of poly(amidoamine) dendrimer in which gold quantum dots are entrapped.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gold quantum dot-entrapped poly(amidoamine) dendrimer nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_551 gold quantum dot-entrapped poly(amidoamine) dendrimer nanoparticle antibody <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of protein made by B lymphocytes in response to a foreign substance (antigen). Each antibody only binds to a specific antigen, helping to destroy the antigen directly or by assisting white blood cells to destroy the antigen.[source: NCI_Thesaurus]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>antibody</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MESH:D000906 NCIT: C16295 NPO_552 antibody diamagnetic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Magnetic property exhibited in materials which create a weak magnetic field in opposition to an externally applied magnetic field; thus, causing repulsion of the material in a magnetic field.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>diamagnetic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_553 diamagnetic fermium atom 100 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 100.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fermium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_554 fermium atom block element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy some orbital.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>block element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_555 block element taxane-pocket binding agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Tubulin binding agent that binds to the taxane site of the beta-tubulin subunit, a region described as a binding pocket located within the middle domain and corresponding to an approximate residue sequence of 217-231. Specifically, these agents bind to a cysteine residue within the pocket, which is also the binding site for GTP. Agents binding at the taxane site promote the polymerization of dimers to form a very rigid and stable microtubule structure which is not readily disassembled. Interfering with microtubule dynamics, these agents inhibit the normal turnover process essential during mitosis, thereby causing cell-cycle arrest and/or apoptosis. [source: NCIT]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>taxane-pocket binding agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C67437 NPO_556 taxane-pocket binding agent indium atom 49 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 49.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>indium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_557 indium atom niobium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 41.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>niobium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_558 niobium thiocyanate compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thioyanate compound is an organic compound which is characterized by the presence of a thiocyanate group. It has the structure R-S-C#N, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thiocyanate compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_560 thiocyanate thiocyanate compound platinum atom 78 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 78.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>platinum atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_561 platinum atom anticancer drug directed against endothelial growth factor receptor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed to affect the synthesis and function of a receptor of an endothelial growth factor.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>anticancer drug directed against endothelial growth factor receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_562 anticancer drug directed against endothelial growth factor receptor covalent linkage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An attachment formed via covalent bonding between chemical groups of molecular entities.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>covalent linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_563 covalent attachment covalent conjugation covalent linkage antineoplastic activity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process that prevents or inhibits the maturation ,growth or spread of tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>antineoplastic activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_564 antineoplastic activity nanoparticle response to stimulus <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process, which describes the function or activity of a nanoparticle, occurring in response to a stimulus acting on the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to stimulus</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_565 nanoparticle response to stimulus ionizable to gain positive charge <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ionizable property inhering in a chemical substance by virtue of having the ability to be ionized and gain a positive charge.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ionizable to gain positive charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_566 ionizable to gain positive charge tyrosine kinase inhibitor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A protein kinase inhibitor, which inhibits tyrosine kinase enzyme, involved with the transduction and processing of many extracellular and intracellular signals including cell proliferation.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tyrosine kinase inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C1967 NPO_567 tyrosine kinase inhibitor iron <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 26.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iron</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_568 iron roentgenium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 111.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>roentgenium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_570 roentgenium vanadium atom 23 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 23.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>vanadium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_571 vanadium atom drug directed against tumor RNA <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Anticancer drug which is directed to interfere with the synthesis, function or activity of mRNA.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>drug directed against tumor RNA</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_572 drug directed against tumor RNA inhibitor role <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role borne by a molecular entity which prevents or slows down an activity or process; or that reduces the activity of another molecular entity.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inhibitor role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_576 inhibitor role cetuximab <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A recombinant, chimeric monoclonal antibody directed against the epidermal growth factor receptor (EGFR) with antineoplastic activity. Cetuximab binds to the extracellular domain of the EGFR, thereby preventing the activation and subsequent dimerization of the receptor; the decrease in receptor activation and dimerization may result in an inhibition in signal transduction and anti-proliferative effects. This agent may inhibit EGFR-dependent primary tumor growth and metastasis. EGFR is overexpressed on the cell surfaces of various solid tumors.[source: NCI_Thesaurus]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cetuximab</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Erbitux NCIT:C1723 NPO_577 cetuximab drug directed against extracellular domain of membrane receptor praseodymium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 59.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>praseodymium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_579 praseodymium imine linkage between secondary amine and aldehyde <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imine linkage which is formed between a secondary amine and an aldehyde, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>imine linkage between secondary amine and aldehyde</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_580 imine linkage between secondary amine and aldehyde dipole-dipole interaction <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An intermolecular interaction between molecules (polar or non-polar) due to attraction between permanent or temporary molecular dipoles.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dipole-dipole interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_582 Van Der Waals Interaction dipole-dipole interaction polypeptide chain <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polypeptide, which is part of some protein molecule.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polypeptide chain</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_585 polypeptide chain hassium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 108.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hassium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_586 hassium lutetium atom 71 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 71.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lutetium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_587 lutetium atom quantum dot (NCI_Thesaurus definition): Nanometer-sized semiconductor particles, made of cadmium selenide (CdSe), cadmium sulfide (CdS) or cadmium telluride (CdTe) with an inert polymer coating. The semiconductor material used for the core is chosen based upon the emission wavelength range being targeted: CdS for UV-blue, CdSe for the bulk of the visible spectrum, and CdTe for far red and near-infrared. The size of the particle determines the exact color of a given quantum dot. The polymer coating protects cells from cadmium toxicity but also facilitates the attachment of a variety of targeting molecules, including monoclonal antibodies directed to tumor-specific biomarkers. Because of their small size, quantum dots can function as cell- and even molecule-specific markers that will not interfere with the normal cellular functions. <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A three-dimensional nanoparticle which is made of material that exhibits quantum effects.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>quantum dot</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_589 QD quantum dot gold atom 79 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 79.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gold atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_591 gold atom terbium atom 65 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 65.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>terbium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_592 terbium atom DNA synthesis inhibitor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antineoplastic agent, which inhibits the synthesis of DNA.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>DNA synthesis inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DNA synthesis inhibitor NPO_594 photosensitizing agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anticancer drug that is pharmacologically inactive but when exposed to ultraviolet light or sunlight, it is converted to its pharmacologically active metabolite.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>photosensitizing agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MESH: D017319 NCIT: C1420 NPO_596 photosensitizer photosensitizing agent mitroxantrone <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound which functions as a topoisomerase-II inhibitor and an antineoplastic antibiotic.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mitroxantrone</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C62050 NPO_597 anticancer drug that inhibits protein activity related to DNA synthesis mitroxantrone insoluble in water <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A qualitative measure of "solubility in water" which indicates the poor ability of the chemical substance to dissolve in water under specific conditions.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>insoluble in water</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_598 insoluble in water water-insoluble labeling role <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role played by a material entity when it is used for labeling another material entity.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>labeling role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_599 labeling role gel <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A colloid, which is a semi-solid or jelly like material formed by the coagulation of a colloidal liquid.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gel</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_601 gel carbon nanofiber <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanofiber which is composed of graphene layers arranged as stacked cones, cups or plates. Carbon nanofibers with graphene layers wrapped into perfect cylinders are called carbon nanotubes.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carbon nanofiber</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_602 carbon nanofiber rhenium atom 75 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 75.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>rhenium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_604 rhenium atom tumor targeting <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The process of directing a molecule or a particle to a specific location in a tumor.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tumor targeting</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_605 tumor targeting carbon nanotube <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanotube which consists of one or more graphite sheets (graphene) of hexagonal arrays of carbon rolled into seamless cylinders with capped ends.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carbon nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_606 carbon nanotube germanium atom 32 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 32.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>germanium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_609 germanium atom argon atom 18 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 18.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>argon atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_610 argon atom Group 10 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 10 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Group 10 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Group 10 Element NPO_611 nickel group element hollow core of nanocage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The hollow core region of a nanocage.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hollow core of nanocage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_612 hollow core of nanocage lead atom 51 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 51.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lead atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_613 lead atom ketone group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carbonyl group which is characteristic of a ketone wherein it is attached to two carbon atoms via covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ketone group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_614 ketone group oxygen <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 8.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>oxygen</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_615 oxygen endothelial-specific integrin inhibitor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An angiogenesis inhibitor that acts by blocking the action of endothelial integrins. An endothelial-specific integrin/survival signaling inhibitor binds to and blocks the activity of endothelial-specific integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>endothelial-specific integrin inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C2144 NPO_616 [definition source]: NCI_Thesaurus endothelial-specific integrin inhibitor survival signaling inhibitor nanoparticle response to internal stimulus <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to stimulus, which occurs in response to the internal stimulus acting on the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to internal stimulus</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_617 nanoparticle response to internal stimulus paclitaxel-loaded nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is loaded with paclitaxel.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>paclitaxel-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_618 paclitaxel-loaded nanoparticle nanocage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A three-dimensional nanoparticle with a hollow core and a porous wall or shell. It's structure resembles that of a hollow cage, that is similar to a fullerene type of nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanocage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_619 nanocage DNA crosslinking agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>DNA binding agent that is able to covalently bind to DNA causing inter- or intra-stranded cross-linking of DNA. The cross-linking results in misreading of the DNA code and inhibition of DNA synthesis.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>DNA crosslinking agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DNA crosslinking agent NCIT:C25760 NPO_620 dendrimer repeat unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecule component in dendrimer which repeats to form the branches of a dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dendrimer repeat unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_621 dendrimer repeat unit hassium atom 108 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 108.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hassium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_622 hassium atom nitrogen atom 7 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 7.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nitrogen atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_623 nitrogen atom Group 2 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 2 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Group 2 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Group 2 Element NPO_625 amide linkage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an amide group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>amide linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_626 amide bond amide linkage acoustic-sensitive <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition, inhering in any material entity, whose structure or function can be altered by sound.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>acoustic-sensitive</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_627 acoustic-sensitive ionizability <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity that inheres in a molecular entity or group, and that describes the ability of the bearer to be ionized.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ionizability</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_628 ionizability Group 9 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 9 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Group 9 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Group 9 Element NPO_630 cobalt group element solid lipid nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle whuch is basically composed of solidified lipid molecules.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>solid lipid nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_631 solid lipid nanoparticle anticancer drug based on target <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Anticancer drug, which is the role of a molecular entity, realized from the kind of biological target where the molecular entity is primarily intended or directed to act.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>anticancer drug based on target</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_633 [classification source]: E. Espinosa, P. Zamora, J. Feliu and M. G. Baron, Classification of anticancer drugs-a new system based on therapeutic targets, Cancer Treatment Reviews, 29: 515-523 (2003). anticancer drug based on target ferromagnetic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Magnetic property exhibited by materials in presence of an external magnetic field and the magnetism is retained for a period even after the magnetic field is removed (magnetic moments of the adjacent atoms are aligned in the same direction at temperatures below the Curie temperature).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ferromagnetic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_634 ferromagnetic payload agent role <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecule role in nanoparticle, which inheres in a molecular entity that has active end-directed functions/activities and is transported and delivered by the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>payload agent role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_635 payload agent role nanosphere <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A three-dimensional nanoparticle which is spherical, porous or non-porous and its diameter is measured in nanometers.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanosphere</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_636 nanosphere amidine linkage between primary amine and imidoester <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amidine linkage which occurs between a primary amine and an imidoester, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>amidine linkage between primary amine and imidoester</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_637 amidine linkage between primary amine and imidoester sensitivity to stimulus <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition, inhering in any material entity, whose structure or function can be altered by a stimulus.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sensitivity to stimulus</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_638 sensitivity to stimulus emulsion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A colloid in which both phases are liquids that are immiscible with each other.[source: WordNet 3.0]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>emulsion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C63807 NPO_639 [source]: http://www.thefreedictionary.com emulsion imide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imide is an amide which is characterized by the presence of an imide group. It has the structure R-C(=O)-N(-R')-C(=O)-R", where R, R" denote organic groups, and R' stands for organic group or hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>imide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_640 imide material site <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An independent continuant [snap:IndependentContinuant] consisting of a characteristic spatial shape in relation to some arrangement of material entities and of the medium which is enclosed in whole or in part by this characteristic spatial shape. Material site entities are entities that can be occupied by other material entities.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>material site</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> A foreign molecule could be covalently linked to a molecular constituent or it could occupy a void space / cavity by participating in non-covalent interactions iwth neighboring molecular constituents. NPO_641 [previous definition]: An independent continuant which describes any distinguishable point, site or location in a material entity, and the location is either that of a group of molecular constituents in a material entity, or the space surrounded by the molecular constituents. definition of material site is based on the definition of snap:Site material site dendrimer cavity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A material site which is a cavity or space formed within the core and generation layer (between branches) of a dendrimer. It can be occupied by molecules other than those which chemically make up the dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dendrimer cavity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_642 dendrimer cavity fluorochrome <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fluorescent dye which is used to stain a specimen or a sample in fluorescence microscopy.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluorochrome</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C503 NPO_643 fluorochrome thioether linkage between thiol and iodoacetyl derivative <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thioether linkage which occurs between a thiol and an iodoacetyl derivative, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thioether linkage between thiol and iodoacetyl derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_644 thioether linkage between thiol and iodoacetyl derivative topotecan <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A semisynthetic derivative of camptothecin, a cytotoxic, quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>topotecan</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_645 topotecan halogen atom <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom of fluorine or chlorine or bromine or iodine or astatine.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>halogen atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_646 halogen atom arylthioether linkage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an arylthioether group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>arylthioether linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_648 arylthioether linkage heterobifunctional crosslinker <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A crosslinking agent which contains two different end reactive groups connected by a spacer, and the two reactive groups can couple to two different functional groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>heterobifunctional crosslinker</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_649 heterobifunctional crosslinker succinimidyl carbonate compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound which is characterized by the presence of a succinimidyl carbonate group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>succinimidyl carbonate compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_650 succinimidyl carbonate compound radium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 88.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>radium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_651 radium thorium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 90.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thorium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_652 thorium stimulus of pH change <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An internal stimulus for nanoparticle function, which is caused by a change in pH of the medium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>stimulus of pH change</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_653 stimulus of pH change einsteinium atom 99 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 99.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>einsteinium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_654 einsteinium atom intermolecular interaction <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An attractive non-covalent interaction between two or more (otherwise non-associated) molecules.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>intermolecular interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_655 intermolecular interaction Period 5 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the fifth row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Period 5 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_656 Period 5 Element sufur atom 16 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 16.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sufur atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_658 sufur atom noble gas <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A non-metal which is any of the following elements: argon, helium, krypton, neon, radon, xenon.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>noble gas</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_660 inert element noble gas core-shell nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a core part and a shell part, and both the core and shell are distinguished by their respective material content.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>core-shell nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_661 core-shell nanoparticle drug release from nanoparticle in response to magnetic field <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to magnetic field, which involves the release of drugs from a drug-loaded nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>drug release from nanoparticle in response to magnetic field</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_662 drug release from nanoparticle in response to magnetic field astatine <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 85.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>astatine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_663 astatine Group 8 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 8 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Group 8 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Group 8 Element NPO_664 iron group element nanocantilever <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as the simplest micro-electro-mechanical system (MEMS) that is easily machined and mass-produced for probing nanoscale specimens.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanocantilever</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_665 Nanocantilevers are often used to explore and characterize the surfaces of biological systems. The motion of the device is recorded and transformed mathematically to provide information about these surface characteristics. nanocantilever hexahedral shape <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A polyhedral shape that inheres in a 3-dimensional object having six plane faces.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>hexahedral shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_666 [source]: WordNet hexahedral hexahedral shape one-dimensional nanoparticle 1-D nanoparticle <ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has only one external dimension in the nanoscale size range.</ncicp:def-definition><ncicp:Definition_Review_Date>110104</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>one-dimensional nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_667 one-dimensional nanoparticle tellurium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 52.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tellurium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_668 tellurium inorganic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in a molecular entity which does not contain carbon as a principal element (some exceptions exist, e.g., carbon dioxide).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inorganic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C66829 NPO_669 inorganic liquid <ncicp:ComplexDefinition><ncicp:def-definition>A fluid state of matter having no fixed shape but a fixed volume.</ncicp:def-definition><ncicp:Definition_Review_Date>130524</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>liquid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C45298 NPO_670 liquid exterior surface of dendrimer <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The exterior surface of a dendrimer formed by the dendrimer's end/surface groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>exterior surface of dendrimer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_671 exterior surface of dendrimer material entity <ncicp:ComplexDefinition><ncicp:def-definition>An independent continuant [snap:IndependentContinuant] which is spatially extended and composed of matter. The identity of material entities is independent of that of other entities and can be maintained through time.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>material entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Matter is any physical substance that has mass and occupies space. NPO_672 material entity snap:MaterialEntity arsenic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 33.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>arsenic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_673 arsenic Period 2 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the second row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Period 2 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_674 Period 2 Element stimulus of magnetic field <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by magnetic field.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>stimulus of magnetic field</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_675 stimulus of magnetic field biopolymer-coated nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a coating agent composed of a biopolymer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>biopolymer-coated nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_677 biopolymer-coated nanoparticle platinum <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 78.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>platinum</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_678 platinum technetium atom 43 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 43.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>technetium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_679 technetium atom carboxylic ester group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)-O- and it is formally derived from carboxylic acid and organic hydroxy compound. The group is characteristic of a carboxylic ester compound wherein it is attached to two carbon atoms via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carboxylic ester group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_682 carboxylic ester group polar covalent bonding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent bonding in which the sharing of electron pair is unequal due to difference in the electronegativities of atoms that share the electron pair.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polar covalent bonding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_683 polar covalent bonding nanoprobe <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as a probing tool of nanometer-size, and combined with a nanosensor, is useful for subcellular detection of activity or phenomenon (e.g. biological phenomenon or process).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoprobe</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C62372 NPO_684 nanoprobe targeting agent <ncicp:ComplexDefinition><ncicp:def-definition>A molecule which is used for targeting other molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>targeting agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_685 targeting agent fullerene <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fullerene refers to any cagelike, hollow molecule composed of hexagonal and/or pentagonal groups of carbon atoms , and it is regarded as the third form of carbon after diamond and graphite.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fullerene</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_686 fullerene carbonate ester group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -O-C(=O)-O-. The group is characteristic of a carbonate ester molecule wherein it is attached to two carbon atoms via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carbonate ester group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_687 carbonate ester group bismuth <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 83.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>bismuth</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_688 bismuth specific collective quality <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which inheres in a group of multiple bearers AND specific only to the type of bearers in the group.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>specific collective quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_689 specific collective quality iron atom 26 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 26.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iron atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_690 iron atom nanoarray <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as a template consisting of two-dimensional patterning of biological molecules on a surface for biological analysis.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoarray</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C62340 NPO_691 nanoarray Group 3 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 3 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Group 3 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Group 3 Element NPO_694 scandium group element dendrimer end group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular component which is a functional group that is part of a dendrimer and it is located at the surface of a dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dendrimer end group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_695 dendrimer end group terminal group amine group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which is formally derived by the removal of one or more hydrogen atoms from ammonia, by virtue of which it has the structure -NH2 or -NH- or -N(-)-. The group is characteristic of an amine molecule wherein it is attached to hydrocarbyl groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>amine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_696 amine group amino group cerium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 58.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cerium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_697 cerium tamoxifen-loaded nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle loaded with tamoxifen.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tamoxifen-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_699 tamoxifen-loaded nanoparticle stimulus of sound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by sound.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>stimulus of sound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_701 stimulus of sound Group 12 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 12 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Group 12 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Group 12 Element NPO_702 zinc group element americium atom 95 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 95.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>americium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_704 americium atom nanochannel <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as an in vivo implantable device, designed to deliver drugs under zero order rate kinetics at high local drug concentrations to non-resectable tumor lesions.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanochannel</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_705 [definition source]: Lesinski et al, Biomedical Microdevices, vol 7, number 1, 71-79, 2005 nanochannel calcium atom 20 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 20.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>calcium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_706 calcium atom nanoparticle <ncicp:ComplexDefinition><ncicp:def-definition>A primary particle which has an average size in the nanoscale range; which has an identifiable and definite chemical composition, property or function that uniquely define the nanoparticle's type as known; and, which may or may not exhibit a size-intensive property.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Definition is partly based on ASTM E 2456-06 (Terminology for Nanotechnology). NPO_707 nanoparticle potassium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 19.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>potassium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_708 potassium actinium atom 89 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 89.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>actinium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_709 actinium atom phosphorus atom 15 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 15.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>phosphorus atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_710 phosphorus atom nanobud <ncicp:ComplexDefinition><ncicp:def-definition>A nanostructured material which is formed by the combination of single-walled carbon nanotubes and fullerenes wherein the fullerenes are covalently bonded to the outer surface of the nanotubes.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanobud</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_711 [definition source]: Nasibulin, A. G., Peter. V. Pikhitsa, Hua. Jiang, David. P. Brown, A. V. Krasheninnikov, Anton S. Anisimov, Paula Queipo, Anna Moisala, David Gonzalez, Gunther Lientschnig, Abdou Hassanien, Sergey D. Shandakov, Giulio Lolli, Daniel E. Resasco, Mansoo Choi, David Tománek, and Esko I. Kauppinen "A Novel Hybrid Carbon Nanomaterial". Nature Nanotechnology 2(3), 156-161 (2007). nanobud homobifunctional crosslinker <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A crosslinker which has two identical reactive ends connected by a carbon chain spacer and are used mostly to crosslink molecules or parts of molecules in a one-step chemical crosslinking procedure.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>homobifunctional crosslinker</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_713 homobifunctional crosslinker periodic table element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table of elements.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>periodic table element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_714 periodic table element drug release from nanoparticle in response to ultrasound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to ultrasound, which involves the release of drugs from a drug-loaded nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>drug release from nanoparticle in response to ultrasound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_715 drug release from nanoparticle in response to ultrasound thorium atom 90 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 90.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thorium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_716 thorium atom external stimulus for nanoparticle function <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A stimulus for nanoparticle function, which originates from a source that is outside of the the medium in which the nanoparticle is located.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>external stimulus for nanoparticle function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_717 external stimulus for nanoparticle function s-block element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electron is in an s-orbital.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>s-block element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_718 s-block element liposome <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A supramolecular structure which is a closed vesicle that forms on hydration of dry phospholipids above its transition temperature.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>liposome</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_719 liposome liposome vesicle cyanate group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure N#C-O-. The group is characteristic of a cyanate molecule wherein it is attached to an organic group via a single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cyanate group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_720 cyanate group chitosan <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A linear polysaccharide of deacetylated beta-1,4-D-glucosamine; deacetylated chitin.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chitosan</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MESH:D048271 NPO_721 chitosan palladium atom 46 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 46.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>palladium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_722 palladium atom nanocell <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A three-dimensional nanoparticle which consists of a nuclear core surrounded by a lighter lipid membrane.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanocell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_723 Nanocell was first used for sequential delivery of anti-angiogenesis and chemotherapeutic agent to solid tumors.The chemotherapeutic agent can be conjugated to a nanoparticle in the core, while the anti-angiogenesis agent can be encapsulated in the lipid membrane.It was designed to first cause membrane disruption for release of anti-angiogenesis agent, which causes tumor vascular collapse, and finally cause intra-tumoral trapping of the core chemotherapeutic drug-conjugated nanoparticles. [definition source]: Sengupta et al, Nature Letters, vol 436, 2005 nanocell Nanocapsule <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A three-dimensional nanoparticle which consists of a shell and a space, in which desired substances may be placed. It can be cylindrical or spherical in shape.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanocapsule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_724 nanocapsule amidine group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -E(=N-)-NH2, where E could denote carbon (C) or (Sulfur). The group is characteristic of an amidine compound.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>amidine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_725 amidine group technetium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 43.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>technetium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_726 technetium neptunium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 93.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>neptunium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_727 neptunium general collective quality <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which inheres in a group of multiple bearers AND NOT specific only to the type of bearers in the group.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>general collective quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_728 general collective quality iron oxide nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of iron oxide.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iron oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_729 iron oxide nanoparticle buckyball <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Buckyball (C60) or Buckministerfullerene, is a type of fullerene which comprises of 60 carbon atoms arranged in interlocking hexagons and pentagons, like the patches on a soccer ball. Its geometry is roughly spherical and it has a hollow interior.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>buckyball</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_730 buckyball stimulus of heat <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by heat.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>stimulus of heat</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_731 stimulus of heat amphiphilic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable property which inheres in a molecule that has both hydrophobic and hydrophilic parts.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>amphiphilic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_732 amphipathic amphiphilic element <ncicp:ComplexDefinition><ncicp:def-definition>A pure substance which is made up of one type of atom, and it cannot be decomposed or transformed by a chemical reaction into a different substance, although it can be transmutated into an isotope through a nuclear reaction.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_733 element dendrimer <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polymeric molecule which has a highly-branched, three-dimensional tree-like architecture, synthesized from monomers where shells of branched molecules are added in discrete steps to a central core.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dendrimer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MESH:D050091 NPO_735 [MeSH definition]: Tree-like, highly branched, polymeric compounds. They grow three-dimensionally by the addition of shells of branched molecules to a central core. The overall globular shape and presence of cavities gives potential as drug carriers and CONTRAST AGENTS. [NCI_THESAURUS definition]: A polymeric molecule which has a highly-branched, three-dimensional architecture. Dendrimers are synthesized from monomers and new branches are added in discrete steps to form a tree-like architecture. A high level of synthetic control is achieved through step-wise reactions and purification at each step to regulate the size, architecture, functionality and monodispersity of the molecules. These polymers have desirable pharmacokinetic properties and a polyvalent array of surface groups that make them potential drug delivery vesicles. dendrimer silver <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 47.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>silver</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_736 silver antineoplastic antibiotic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antineoplastic agent isolated naturally from microorganisms or synthesized chemically that kills or inhibits the growth of tumor cells. Antineoplastic antibiotics can interfere with the normal function of cellular nucleic acids and proteins.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>antineoplastic antibiotic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C259 NPO_737 anticancer antibiotic antineoplastic antibiotic antitumor antibiotic amide linkage between primary amine and carboxylic ester <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide linkage which is formed between a primary amine and a carboxylic ester.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>amide linkage between primary amine and carboxylic ester</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_738 amide linkage between primary amine and carboxylic ester yttrium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 39.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>yttrium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_739 yttrium acyl bromide group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl halide group in which the halogen atom is a "bromine atom."</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>acyl bromide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_740 acyl bromide group tin <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 50.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_742 tin instantaneous dipole-induced dipole interaction <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dipole-dipole interaction between non-polar molecules due to attraction between an instantaneous dipole on one non-polar molecule and an induced dipole on the other non-polar molecule; the temporary dipole on the latter molecule is induced by the randomly occurring (temporary) instantaneous dipole of the former molecule.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>instantaneous dipole-induced dipole interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_743 induced dipole-induced dipole interaction instantaneous dipole-induced dipole interaction london force Group 11 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 11 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Group 11 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Group 11 Element NPO_744 copper group element carboxylic ester linkage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a carboxylic ester group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carboxylic ester linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_745 carboxylic ester linkage ester linkage xenon <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 54.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>xenon</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_746 xenon sulfonamide group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide group which has the structure -S(=O)-NH2 or -S(=O)-NH- or -S(=O)-N(-)-. The group is characteristic of a sulfonamide wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sulfonamide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_747 sulfonamide group diazo linkage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a diazo group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>diazo linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_748 diazo linkage stimulus for nanoparticle function <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process which describes an action or event that triggers a specific function of a nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>stimulus for nanoparticle function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_751 stimulus for nanoparticle function internal stimulus for nanoparticle function <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A stimulus for nanoparticle function, which originates from a source that is inside the medium in which the nanoparticle is located.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>internal stimulus for nanoparticle function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_752 internal stimulus for nanoparticle function gadolinium atom 64 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 64.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gadolinium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_753 gadolinium atom osmium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 76.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>osmium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_754 osmium metalloid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with properties between a metal and a non-metal.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>metalloid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_755 metalloid nanoparticle response to infrared light <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to external stimulus, which occurs in response to infrared light.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to infrared light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_756 nanoparticle response to infrared light cerium atom 58 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 58.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cerium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_757 cerium atom chloro group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A halo group in which the halogen atom is a chlorine atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chloro group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_758 chloro group nanofilm <ncicp:ComplexDefinition><ncicp:def-definition>A thin layer of nanostructured material.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanofilm</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_759 nanofilm shell <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A fiat material part which is a material layer surrounding the core.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_760 shell cadmium atom 48 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 48.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cadmium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_761 cadmium atom silicon nanotube <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanotube which consists of one or more sheets of hexagonal arrays of silicon rolled into seamless cylinders with capped ends.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>silicon nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_762 silicon nanotube water-dispersible <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity inhering in particles (e.g, nanoparticles), which gives the bearer the ability to disperse in an aqueous medium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>water-dispersible</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_763 water-dispersible organic compound or molecule <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule, in which carbon is the principal element.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>organic compound or molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_764 organic compound organic compound or molecule organic molecule zirconium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 40.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>zirconium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_765 zirconium charge-dipole interaction <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An intermolecular interaction between an ion and a polar molecule by virtue of an attraction between the ionic charge and a permanent dipole on the polar molecule.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>charge-dipole interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_766 charge-dipole interaction the polar molecule has permanent molecular dipole moment. stimulus of ultraviolet light <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by ultraviolet light.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>stimulus of ultraviolet light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_767 stimulus of ultraviolet light nanopore <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A material site which is a nanoscale cavity or channel confined within a membrane or solid matter.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanopore</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C62343 NPO_768 [NCI_Thesaurus definition]: A nanoscale cavity or channel confined within a membrane or solid matter. nanopore silver atom 47 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 47.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>silver atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_770 silver atom hydrogel <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A colloidal gel in which water is the dispersion medium.[source: WordNet 2008]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrogel</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_771 hydrogel molybdenum atom 42 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 42.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molybdenum atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_772 molybdenum atom promethium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 61.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>promethium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_773 promethium terbium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 65.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>terbium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_775 terbium dendrimer branch <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular structure which is a branch of a dendrimer, formed by the dendrimer's repeating units.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dendrimer branch</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_776 dendrimer branch tumor angiogenesis inhibition <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process or mechanism which inhibits tumor angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tumor angiogenesis inhibition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C26044 NPO_778 inhibition of tumor angiogenesis tumor angiogenesis inhibition tumor angiogenic inhibition nanosensor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as a sensor/detector of any activity, phenomenon or molecule, within a nanometer-range resolution; it responds to a stimulus by sending a signal that can be measured.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanosensor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C62374 NPO_779 nanosensor actinium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 89.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>actinium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_781 actinium lithium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 3.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lithium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_782 lithium topoisomerase-II inhibitor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Topoisomerase inhibitor which either stabilizes DNA-protein complexes damaging DNA (e g., teniposide), or inhibits the catalytic activity of the topoisomerase (e.g., merbarone).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>topoisomerase-II inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C1968 NPO_784 topoisomerase-II inhibitor type II topoisomerase inhibitor gas <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fluid having neither independent shape nor volume and being able to expand indefinitely.[source:NCI]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gas</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C45299 NPO_785 gas non-polar <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in a molecule or chemical bond due to the absence of dipole moments.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>non-polar</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_786 non-polar scandium atom 21 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 21.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>scandium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_787 scandium atom aromatic aminoacid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aminoacid which is aromatic in nature.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>aromatic aminoacid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_791 aromatic aminoacid outer surface of nanotube <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The outer surface of a nanotube to which other molecular entities can be attached. (For example, attachment of fullerene on the surface of carbon nanotube.)</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>outer surface of nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_792 outer surface of nanotube zero-length crosslinker <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cross-linking agent for mediating the conjugation of two molecules by forming a bond between functional groups of the molecule while containing no additional atoms.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>zero-length crosslinker</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_794 zero-length crosslinker cobalt <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 27.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cobalt</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_795 cobalt sulfur <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 16.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sulfur</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_796 sulfur thioether <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thioether is an organic compound which is characterized by the presence of a thioether group. It has the structure R-S-R', where R, R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thioether</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_797 thioether tungsten <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 74.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tungsten</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_799 tungsten PEGylated nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a coating agent composed of polyethylene glycol.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>PEGylated nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_801 PEG-coated nanoparticle PEG-modified nanoparticle PEGylated nanoparticle poly(ethylene) glycol-coated nanoparticle organic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in a molecular entity which contains carbon as a principal element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>organic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C63848 NPO_802 definition for organic is based on the CHEBI definition for organic compounds (CHEBI:25700) organic dendrimer core molecule <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecule component in dendrimer which forms the core of a dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dendrimer core molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_803 core initiator group dendrimer core molecule nickel <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 28.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nickel</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_804 nickel thulium atom 69 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 69.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thulium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_806 thulium atom amide linkage between primary amine and carboxylic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide linkage which is formed between a primary amine and a carboxylic acid.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>amide linkage between primary amine and carboxylic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_807 amide linkage between primary amine and carboxylic acid arsenic atom 33 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 33.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>arsenic atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_808 arsenic atom rutherfordium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 104.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>rutherfordium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_809 rutherfordium titanium atom 22 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 22.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>titanium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_810 titanium atom stimulus of temperature change <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An internal stimulus for nanoparticle function, which is caused by a change in temperature.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>stimulus of temperature change</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_811 stimulus of temperature change bromine atom 35 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 35.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>bromine atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_812 bromine atom tellurium atom 52 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 52.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tellurium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_813 tellurium atom fluid <ncicp:ComplexDefinition><ncicp:def-definition>A chemical substance which deforms under an applied stress, and conforms to the outline of its container.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C25278 NPO_815 fluid ruthenium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 44.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ruthenium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_816 ruthenium zinc <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 30.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>zinc</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_818 zinc darmstadtium atom 110 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 110.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>darmstadtium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_819 darmstadtium atom polydispersity <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a collection of objects based on size or molecular weights (e.g., particles, polymers).</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polydispersity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_821 polydispersity phosphoramide group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide group which has the structure -P(=O)-NH2 or -P(=O)-NH- or -P(=O)-N(-)-. The group is characteristic of a phosphoramide wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>phosphoramide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_822 phosphoramide group monoclonal antibody <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antibody produced by a clone or genetically homogenous fast-growing cells i.e., hybridoma. Hybridoma cells are cloned to establish cell lines producing a specific antibody that is chemically and immunologically homogeneous.[source: NCI_Thesaurus]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>monoclonal antibody</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MAb NCIT:C20401 NPO_823 monoclonal antibody carboxamide group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A amide group which has the structure -C(=O)-NH2 or -C(=O)-NH- or -C(=O)-N(-)-. The group is characteristic of a carboxamide wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carboxamide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_824 carboxamide group fluoro group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A halo group in which the halogen atom is a fluorine atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluoro group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_825 fluoro group surface modifying agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component in a nanoparticle formulation, which is there to modify the nanoparticle's surface properties like surface charge or surface hydrophilicity; or 2) to which other molecular entities can be attached for facilitating linkage between the molecular entities and the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoparticle surface modifying agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_827 coating agent nanoparticle surface modifying agent micelle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A supramolecular structure which is an aggregate of amphiphilic molecules in a polar solvent.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>micelle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_829 micelle target role <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role played by a material entity that serves as the target for a targeting agent in a targeting process.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>target role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_830 role of a target target role carboxylate group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group derived by the removal of a hydrogen atom from a carboxylic acid, by virtue of which it has structure -C(=O)-[O-]. The group is characteristic of a carboxylate compound wherein it is attached to the remaining part of the molecule via a covalent bond between the oxygen atom and a carbon atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carboxylate group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_831 carboxylate group porous shell of nanocage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The porous shell of a nanocage.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>porous shell of nanocage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_833 porous shell of nanocage solid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance which has an ordered 3-dimensional structure due to the closely packed arrangement of constituting atoms, molecules or ions. As a result, the substance has a definite shape and volume, and the shape can be modified under application of a force.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>solid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_834 solid sol <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A colloid that has a continuous liquid phase in which a solid is suspended in a liquid.[source: WordNet 2008]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sol</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C73489 NPO_835 sol biodegradable nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a biodegradable property.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>biodegradable nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_836 biodegradable nanoparticle enhanced permeability and retention effect <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A passive targeting process, which results in the accumulation of particulate substances in angiogenic tumors due to enhanced permeability of particles across leaky tumor endothelium and retention of the particles inside the tumor due to its defective lymphatic drainage system.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>enhanced permeability and retention effect</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> EPR NPO_837 [definition source]: Y. Matsumur and H. Maeda, A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent Smancs, Cancer Research, 46, 6387-6392 (1986). enhanced permeability and retention effect targeting of cancer cells via EPR argon <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 18.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>argon</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_841 argon americium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 95.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>americium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_842 americium arylamine linkage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an arylamine group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>arylamine linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_843 arylamine linkage isothiocyanate <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An isothiocyanate is an organic compound which is characterized by the presence of an isothiocyanate group. It has the structure R-N=C=S, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>isothiocyanate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_844 isothiocyanate p-block element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy p-orbitals.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>p-block element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_845 p-block element dextran <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A glucan which is a high-molecular-weight polymer of d-glucose, produced by enzymes on the cell surface of certain lactic acid bacteria.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dextran</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> MESH:D003911 NPO_846 dextran plutonium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 94.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>plutonium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_847 plutonium polypeptide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A peptide which consists of several aminoacids .</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polypeptide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_848 polypeptide Period 7 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the seventh row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Period 7 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_849 Period 7 Element elliptical shape <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape formed by a closed, curve whose path is traced by a point moving in a plane such that the sum of its respective distances from two fixed points (the ellipse's foci) is constant.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>elliptical shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_850 [definition based on source]:http://www.cycfoundation.org, http://www.thefreedictionary.com, NCI elliptical elliptical shape fermium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 100.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fermium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_851 fermium needle shape <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A rod shape inhering in a long and slender rod, which resembles a needle.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>needle shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_852 needle shape vapor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A gas that is a solid or liquid at normal room temperature. [source:NCI]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>vapor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C63390 NPO_854 vapor aliphatic aminoacid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aminoacid which is aliphatic in nature.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>aliphatic aminoacid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_855 aliphatic aminoacid berkelium atom 97 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 97.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>berkelium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_856 berkelium atom carbon <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 6.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carbon</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_857 carbon polyhedral shape <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape inhering in a 3-dimensional object that resembles a solid figure bounded by plane polyons or faces.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>polyhedral shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_858 [source]: WordNet polyhedral polyhedral shape superparamagnetic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Magnetic property -similar to paramagnetism - which is exhibited in materials when the temperature of the material is below the Curie temperature.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>superparamagnetic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_859 superparamagnetic cubical shape <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A regular hexahedral shape that inheres in a 3-dimensional object having six equal squares as faces.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cubical shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_861 [source]:WordNet cubical cubical shape xenon atom 54 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 54.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>xenon atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_862 xenon atom holmium atom 67 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 67.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>holmium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_863 holmium atom topoisomerase-I inhibitor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Topoisomerase inhibitor which inhibits the action of topoisomerase I.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>topoisomerase-I inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_864 topoisomerase-I inhibitor copper atom 29 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 29.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>copper atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_865 copper atom acryloyl compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acryloyl compound is an "organic compound" which is characterized by the presence of an "acryloyl group". It has the structure R-C(=O)-CH=CH2, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>acryloyl compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_866 acryloyl compound acryloyl derivative polydisperse <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A qualitative measure of polydispersity, inhering in a collection of particles that are of different sizes or of polymers that have varying molecular weights.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polydisperse</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_867 polydisperse nanoparticle formulation <ncicp:ComplexDefinition><ncicp:def-definition>A nanomaterial which is a particulate chemical substance that is formulated systematically using nanotechnology, and it contains nanoparticles and active chemical components/ingredients.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoparticle formulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_868 Nanotechnology involves the application of scientific knowledge from multidisciplinary fields of science and engineering, towards understanding, manipulating and controlling the properties of matter at the nanoscale (1-100 nm) size dimensions. nanoparticle formulation beryllium atom 4 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 4.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>beryllium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_869 beryllium atom single-walled nanohorn <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanohorn that is comprised of a single layer of graphitic carbon and exhibits an irregular horn-like shape. One of the primary characteristics of carbon nanohorns is their ability to aggregate. This aggregation is advantageous because of the resulting enhanced permeability in both gases and liquids.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>single-walled nanohorn</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C62387 NPO_870 [definition source]: NCI_Thesaurus single-walled nanohorn Period 4 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the fourth row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Period 4 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_871 Period 4 Element californium atom 98 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 98.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>californium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_872 californium atom antimetastatic agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antineoplastic agent, which prevents or impairs tumor metastasis.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>antimetastatic agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C2196 NPO_873 antimetastatic agent melphalan <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An L-phenylalanine nitrogen mustard.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>melphalan</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C633 NPO_874 anticancer drug that induces breakage of DNA helix melphalan dihydrofolate reductase inhibitor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Enzyme inhibitor that inhibits dihydrofolate reductase by interfering with the conversion of Dihydrofolate to Tetrahydrofolate, causing inhibition of nucleotide biosynthesis and protein synthesis.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dihydrofolate reductase inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C2153 NPO_876 dihydrofolate reductase inhibitor carbon atom 6 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 6.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carbon atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_877 carbon atom stimulus of visible light <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by visible light.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>stimulus of visible light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_878 stimulus of visible light molybdenum <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 42.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molybdenum</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_880 molybdenum hydrophobic core of micelle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Core part of a micelle formed by hydrophobic (non-polar) tails of individual amphiphilic molecules that form the whole micelle in a polar solvent, which has void spaces to include other hydrophobic molecules.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrophobic core of micelle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_881 hydrophobic core of micelle seaborgium atom 106 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 106.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>seaborgium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_885 seaborgium atom permanent dipole-dipole interaction <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An dipole-dipole interaction between two polar molecules due to attraction between their permanent dipoles.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>permanent dipole-dipole interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_886 permanent dipole-dipole interaction disulfide linkage between two thiols <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disulfide linkage which is formed between two thiol compounds, through covalent interactions between atoms of respective sulfhydryl groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>disulfide linkage between two thiols</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_887 disulfide linkage between two thiols physical state <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality, which is the physical condition of a material entity, based on its chemical composition and structure.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>physical state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_888 physical state state of matter secondary amine group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amine group which is formally derived by the removal of two hydrogen atoms from ammonia, by virtue of which it has the structure -NH-. The group is characteristic of a secondary amine molecule wherein it is attached to hydrocarbyl groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>secondary amine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_889 secondary amine group amide linkage between primary amine and acyl azide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide linkage which is formed between a primary amine and an acyl azide.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>amide linkage between primary amine and acyl azide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_891 amide linkage between primary amine and acyl azide monodisperse <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A qualitative measure of polydispersity, inhering in a collection of particles that are of the same size or of polymers that have uniform distribution of molecular weights.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>monodisperse</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_892 monodisperse nanofiber <ncicp:ComplexDefinition><ncicp:def-definition>A two-dimensional nano-object which is an elongated fiber of diameter less than 100 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanofiber</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_893 nanofiber acid anhydride group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)-O-C(=O)-. The group is characteristic of acid anhydrides.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>acid anhydride group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_894 The structure of an acid anhydride is R-C(=O)-O-C(=O)-R', in which two acyl groups are bonded to the same oxygen atom; and , R,R' denote hydrogen atoms or organic groups. acid anhydride group crystal <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A solid which is formed by the solidification of a chemical and having a highly regular atomic structure.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>crystal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C61303 NPO_895 crystal crystalline solid barium atom 56 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 56.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>barium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_897 barium atom aryl halide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound in which a halogen atom is bonded to a carbon atom that is part of an aromatic ring. It is characterized by the presence of aryl halide groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>aryl halide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_898 aryl halide pathologic process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A biological process having an abnormal or deleterious effect at the subcellular, cellular, multicellular, or organismal level. (NCI)</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>pathologic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C16956 NPO_899 pathologic process helium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 2.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>helium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_901 helium active targeting <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The process in which material entities (e.g., nanoparticles) are targeted to tumor sites, cancer cells or intracellular organelles in cancer cells, with the help of molecular agents (conjugated to the material entities) that recognize and bind to specific biological molecules at the target location.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>active targeting</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_903 active targeting folate receptor mediated endocytosis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Receptor mediated endocytosis, which is the process by which cells internalize folate molecules that specifically bind to folate receptors.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>folate receptor mediated endocytosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_904 folate receptor mediated endocytosis three-dimensional nanoparticle 3-D nanoparticle <ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has all three external dimensions in the nanoscale size range.</ncicp:def-definition><ncicp:Definition_Review_Date>101223</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>three-dimensional nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_905 three-dimensional nanoparticle sodium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 11.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sodium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_907 sodium epoxide group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has a three-membered cyclic ether structure, where an oxygen atom is attached to two carbon atoms and the carbon atoms are bonded to each other via single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>epoxide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_909 epoxide group oxirane group Period 6 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the sixth row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Period 6 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_911 Period 6 Element inhibition of cancer cell growth <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process which inhibits or blocks the induction, promotion, maintenance, or completion of cell division in cancer cells.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inhibition of cancer cell growth</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT: C29895 NPO_914 inhibition of cancer cell growth powder <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A solid which corresponds to tiny loose particles, produced by pulverization.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>powder</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C45302 NPO_915 powder unilamellar vesicle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A liposome vesicle that has a single lipid bilayer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>unilamellar vesicle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_916 unilamellar vesicle drug directed against membrane receptor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug directed to interfere with the activity of a membrane protein receptor of the tumor cell.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>drug directed against membrane receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_917 drug directed against membrane receptor acoustic imaging contrast agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A contrast agent, which provides contrast in images captured using acoustic imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>acoustic imaging contrast agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_918 acoustic imaging contrast agent antitumor activity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An activity, which involves the killing of tumor cells; or which causes reduction of tumor size.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>antitumor activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_919 antitumor activity purine antagonist <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic antimetabolite which affects the metabolism and utilization of purines.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>purine antagonist</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C1556 NPO_920 purine antagonist purine inhibitor receptor mediated endocytosis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process by which cells internalize molecules by the inward budding of plasma membrane vesicles containing proteins with receptor sites specific to the molecules being internalized.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>receptor mediated endocytosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_921 receptor mediated endocytosis crosslinking reagent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A reagent containing ends reactive to specific functional groups on molecules for modifying and linking molecules together.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>crosslinking reagent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_922 crosslinker crosslinking agent crosslinking reagent titanium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 22.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>titanium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_924 titanium granule <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A solid which corresponds to any small grainlike particle.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>granule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C61363 NPO_925 granule heat generation in response to stimulus of infrared light <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to infrared light, which involves the generation of heat.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>heat generation in response to stimulus of infrared light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_926 heat generation in response to stimulus of infrared light acyl azide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl azide is an acyl compound which is characterized by the presence of acyl azide group. It has the structure R-C(=O)-[N+]#N, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>acyl azide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_927 acyl azide acyl azide derivative erbium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 68.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>erbium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_928 erbium scandium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 21.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>scandium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_929 scandium ytterbium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 70.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ytterbium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_932 ytterbium krypton <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 36.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>krypton</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_933 krypton chromium atom 24 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 24.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chromium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_934 chromium atom cobalt atom 27 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 27.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cobalt atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_935 cobalt atom lanthanum <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 57.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lanthanum</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_936 lanthanum stimulus of infrared light <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by infrared light.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>stimulus of infrared light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_937 stimulus of infrared light biocompatible <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity that inheres in a material entity and indicates that the bearer has the ability to be harmless to biological systems.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>biocompatible</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_938 biocompatible DNA binding agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic agent that binds to DNA to regulate mechanisms central to cellular function, including DNA replication and gene expression.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>DNA binding agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DNA binding agent NCIT: C2842 NPO_939 non-covalent interaction <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical interaction which is non-covalent in nature and provides the force to hold molecules or parts of molecules together.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>non-covalent interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_940 non-covalent bonding non-covalent interaction nobelium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 102.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nobelium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_942 nobelium single-walled carbon nanotube <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A single-walled nanotube which consists of a single graphite layer or sheet of hexagonal arrays of carbon, rolled into a seamless cylinder with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>single-walled carbon nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_943 SWCNT single-walled carbon nanotube acyl halide group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure R-C(=O)-X, where R denotes an organic group and X, a halogen atom. The group is characteristic of an acyl halide.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>acyl halide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_944 Prefix: haloformyl- ; Suffix: -oyl halide acyl halide group passive targeting <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A physiologically-dependent process by which a material entity reaches tumor sites, cancer cells or intracellular organelles in cancer cells.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>passive targeting</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_945 passive targeting protactinium atom 91 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 91.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>protactinium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_946 protactinium atom selenium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 34.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>selenium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_948 selenium dextran-coated nanoparticle <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a coating agent composed of dextran.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dextran-coated nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_949 dextran-coated nanoparticle aliphatic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic quality inhering in a chemical substance due to the presence of cyclic or acyclic, saturated or unsaturated carbon compounds, but with the exclusion of aromatic quality.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>aliphatic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Definition of aliphatic is based on the CHEBI definition for aliphatic compounds (CHEBI:33653) NPO_950 aliphatic polarity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in a molecule or chemical bond due to the presence or absence of dipole moments.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polarity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_951 polarity uranium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 92.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>uranium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_952 uranium ionizable to gain negative charge <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ionizable property inhering in a chemical substance by virtue of having the ability to be ionized and gain a negative charge.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ionizable to gain negative charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_954 ionizable to gain negative charge thalium atom 81 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 81.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thalium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_955 thalium atom epoxide compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An epoxide compound is an organic compound which is characterized by the presence of an epoxide group. It has the structure R-C1H-CH2-O1, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>epoxide compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_956 epoxide compound epoxide derivative stimulus of pO2 change <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An internal stimulus for nanoparticle function, which is caused by a change in pO2.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>stimulus of pO2 change</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_957 stimulus of pO2 change nobelium atom 102 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 102.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nobelium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_960 nobelium atom anticancer drug that induces breakage of DNA helix <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug directed against the DNA in a tumor cell to inhibit DNA replication.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>anticancer drug that induces breakage of DNA helix</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_961 anticancer drug that induces breakage of DNA helix non-polar covalent bonding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent bonding in which the sharing of electron pair is equal.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>non-polar covalent bonding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_962 non-polar covalent bonding occurs for covalent bond between similar types of atoms or between atoms that have almost zero electronegativity difference. pH-sensitive linker <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A spacer, which can be cleaved in response to a change in pH of the solution containing that spacer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>pH-sensitive linker</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_963 pH-sensitive linker pH-sensitive spacer poly(amidoamine) dendrimer <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dendrimer which contains amide molecules as branches; tertiary amines as branching points and primary amine groups as the terminal or end groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>poly(amidoamine) dendrimer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_965 PAMAM dendrimer poly(amidoamine) dendrimer plutonium atom 94 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 94.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>plutonium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_966 plutonium atom erbium atom 68 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 68.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>erbium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_967 erbium atom oxygen atom 8 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 8.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>oxygen atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_968 oxygen atom hydrazone group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group derived by replacing the =O of an aldehyde or a ketone group with =N-NH2 or =N-NH-R'. It has the structure -C(=N-NH2)- or -C(=N-NH-)-, and the group is characteristic of a hydrazone.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrazone group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_969 hydrazone group curium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 96.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>curium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_970 curium thulium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 69.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thulium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_972 thulium isotope <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material entity which is one of two or more forms of atoms - of a chemical element-that contain the same number of protons but different number of neutrons in their nuclei. Hence an isotope differs from an atom in relative atomic mass and physical properties but not in chemical properties; an isotope is a radioactive form of element.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>isotope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_973 isotope drug release from nanoparticle in response to pH change <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to pH change, which involves the release of drugs from a drug-loaded nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>drug release from nanoparticle in response to pH change</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_975 drug release from nanoparticle in response to pH change cadmium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 48.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cadmium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_976 cadmium magnesium atom 12 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 12.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>magnesium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_977 magnesium atom europium atom 63 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 63.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>europium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_978 europium atom Group 7 Element <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 7 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Group 7 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Group 7 Element NPO_979 manganese group element rutherfordium atom 104 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 104.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>rutherfordium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_980 rutherfordium atom lutetium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 71.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lutetium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_981 lutetium amine-reactive and sulfhydryl-reactive crosslinker <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A heterobifunctional crosslinker, which has an amine-reactive group at one end and a sulfhydryl-reactive group at the other end.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>amine-reactive and sulfhydryl-reactive crosslinker</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_983 amine-reactive and sulfhydryl-reactive crosslinker temperature-sensitive <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition inhering in any material entity, whose structure or function can be altered by changes in temperature.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>temperature-sensitive</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_985 temperature-sensitive carbamate ester group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which contains a carboxylic ester bound to a primary or secondary or tertiary amine group. The group is characteristic of a carbamate ester compound.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carbamate ester group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_986 carbamate ester group disulfide linkage <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a disulfide group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>disulfide linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_987 disulfide linkage thioether linkage between thiol and aziridine derivative <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thioether linkage which occurs between a thiol and an aziridine derivative, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thioether linkage between thiol and aziridine derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_988 thioether linkage between thiol and aziridine derivative bromine <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 35.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>bromine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_989 bromine acyl iodide group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl halide group in which the halogen atom is an iodine atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>acyl iodide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_990 acyl iodide group hafnium <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 72.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hafnium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_991 hafnium Premerged_Concepts NHC50000 Premerged_Concepts This is in support of NCI Edit tab Merge and PreMerge function Preretired_Concepts NHC50001 Preretired_Concepts This is in support of the NCI Edit Tab Retired and Preretire functions Retired_Concept_Current_Year NHC50003 Retired_Concept_Current_Year This is in support of the NCI Edit Tab Retired and Preretire functions Retired_Concepts NHC50002 Retired_Concepts This is in support of the NCI Edit Tab Retired and Preretire functions cysteine 2-amino-3-sulfanylpropanoic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-SH)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cysteine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:15356 Cys NPO_384 cysteine water <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxygen hydride which is a liquid and has the chemical formula H2O</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>water</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:15377 NPO_1561 water glycine <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH2-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>glycine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:15428 Gln NPO_800 aminoacetic acid glycine bromide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion of bromine.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>bromide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:15858 NPO_1046 bromide polynucleotide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A biopolymer composed of nucleotide monomers which are covalently bonded in a long chain.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polynucleotide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:15986 NPO_1000 polynucleotide halide anion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion of halogen element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>halide anion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:16042 NPO_1045 halide anion iodide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion of iodine.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iodide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:16382 NPO_1049 iodide alanine 2-aminopropanoic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>alanine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Ala CHEBI:16449 NPO_540 alanine methionine <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-CH2-S-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>methionine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:16811 Met NPO_158 methionine fluoride <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion of fluorine.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluoride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:17051 NPO_1048 fluoride ketone <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A ketone is a carbonyl compound wherein the carbonyl group is bonded to two carbon atoms. It is characterized by the presence of a ketone group, and therefore, has the structure R-C(=O)-R', where R,R' stand for organic groups and not hydrogen atoms.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ketone</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:17087 NPO_879 ketone phosphoramide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phosphoramide is an amide characterized by the presence of a phosphoramide group. It has the structure R-P(=O)-NH2, R-P(=O)-NH-R' or R-P(=O)-N(-R")-R', where R,R',R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>phosphoramide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:17102 NPO_116 phosphoramide aldehyde <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aldehyde is a carbonyl compound wherein the carbonyl group is bonded to one hydrogen atom, and one organic group or another hydrogen atom. It is characterized by the presence of an aldehyde group, and has the structure R-C(=O)H, where R denotes an organic group or a hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>aldehyde</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:17478 NPO_415 aldehyde prefix: aldo- suffix: -al glycolic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound which has the formula (OH)CH2-C(OH)=O.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>glycolic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:17497 NPO_1558 glycolic acid serine 2-amino-3-hydroxypropanoic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-OH)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>serine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:17822 NPO_494 Ser serine chloride <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion of chlorine.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chloride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:17996 NPO_1047 chloride polysaccharide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A biopolymer which consists of large numbers of monosaccharide residues linked glycosidically.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polysaccharide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:18154 NPO_912 This term is commonly used only for those polysaccharides that contain more than ten monosaccharide residues. [definition source]: CHEBI glycan polysaccharide tyrosine <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(Cc1ccc(O)cc1)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tyrosine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:18186 NPO_906 Try tyrosine glutamic acid 2-aminopentanedioic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2CH2C(OH)=O)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>glutamic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:18237 Glu NPO_974 glutamic acid magnesium (2+) ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic dication of magnesium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>magnesium (2+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:18420 NPO_1056 magnesium (2+) ion acyl group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which is derived by the removal of one or more hydroxyl groups from an oxoacid. It has the structure R-C(=O)-, where R denotes an organic substituent from the oxoacid.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>acyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:22221 NPO_302 acyl group alkanoyl group alkyl group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrocarbyl group which is derived from an alkane by removal of a hydrogen atom from any carbon atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>alkyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Alkyl group is a substituent group from alkane. CHEBI:22323 NPO_931 alkyl group anion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion which is negatively charged.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>anion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:22563 NPO_1030 anion arsenic molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of arsenic.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>arsenic molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:22632 NPO_1094 arsenic molecular entity asparagine 2,4-diamino-4-oxobutanoic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2CH(NH)=O)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>asparagine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Asn CHEBI:22653 NPO_452 asparagine aspartic acid 2-aminobutanedioic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2CH(OH)=O)-C(OH)=OH</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>aspartic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Asp CHEBI:22660 NPO_853 aspartic acid bleomycin <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A glycopeptide, which is isolated from fungus; and with iron, it forms complexes that reduce molecular oxygen to superoxide.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>bleomycin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:22907 NPO_839 bleomycin drug targeted against tumor DNA boron molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of boron.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>boron molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:22916 NPO_1104 boron molecular entity bromine molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of bromine.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>bromine molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:22928 NPO_1089 bromine molecular entity cadmium molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of cadmium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cadmium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:22978 NPO_1124 cadmium molecular entity carbamate ester <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carbamate ester is an organic compound which is characterized by the presence of a carbamate ester group. It has the structure R-O-C(=O)-NH2 or R-O-C(=O)-NH-R' or R-O-C(=O)-N(-R")-R', where R, R', R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carbamate ester</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:23003 NPO_828 carbamate ester carbohydrate <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The generic term 'carbohydrate' includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more terminal groups to carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom, an amino group, a thiol group or similar heteroatomic groups. It also includes derivatives of these compounds. The term 'sugar' is frequently applied to monosaccharides and lower oligosaccharides. Cyclitols are generally not regarded as carbohydrates.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carbohydrate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:23008 MESH: D002241 NCIT: C344 NPO_423 [definition source]: CHEBI carbohydrate carbonyl group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)-. The group is characteristic of a carbonyl compound wherein it is attached to the remaining part of the molecule via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carbonyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:23019 NPO_750 carbonyl group chlorine molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of chlorine.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chlorine molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:23117 NPO_1090 chlorine molecular entity chromium molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of chromium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chromium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:23237 NPO_1126 chromium molecular entity molecular entity <ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity is any molecule, ion, ion pair, radical ion, complex, conformer,etc., identifiable as a separately distinguishable entity.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:23367 NPO_355 molecular entity copper molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of copper.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>copper molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:23377 NPO_1131 copper molecular entity diterpenoid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A terpenoid which has a C20 skeleton.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>diterpenoid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:23849 NPO_659 diterpenoid monoatomic anion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion which consists of a single atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>monoatomic anion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:23905 NPO_1035 monoatomic anion monoatomic cation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cation which consists of a single atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>monoatomic cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:23906 NPO_1039 monoatomic cation fluorine molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of fluorine.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluorine molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:24062 NPO_1091 fluorine molecular entity glycopeptide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A peptide compound in which a carbohydrate component is linked to a peptide component.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>glycopeptide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:24396 NPO_482 glycopeptide molecular structure <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a molecular entity or part thereof, by virtue of its chemical composition and/or connectivity between its constituent atoms; or a complex composition of other molecular entities.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molecular structure</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:24431 NPO_392 molecular structure group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A group is a defined linked collection of atoms or a single atom within a molecular entity.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:24433 NPO_303 group halogen molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a halogen (Group-17) element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>halogen molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:24471 NPO_1084 halogen molecular entity organic heterocyclic compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cyclic organic compound, which has ring members that are atoms of carbon and at least of one other element such as sulfur, oxygen or nitrogen.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>organic heterocyclic compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:24532 NPO_692 organic heterocyclic compound hydroxide <ncicp:ComplexDefinition><ncicp:def-definition>A compound which contains a hydroxy group or salts containing hydroxide (OH(-)).</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydroxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:24651 NPO_1145 hydroxide imine <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imine is an organic compound which is characterized by the presence of a carbon-nitrogen double bond, and has the structure R-C(=N-R")-R', where at least one of R,R',R" is a hydrocarbyl group while the remaining being hydrogen atoms.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>imine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:24783 NPO_734 imine inorganic anion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion which is inorganic.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inorganic anion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:24834 NPO_1036 inorganic anion inorganic molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains no carbon.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inorganic molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:24835 NPO_1027 inorganic molecular entity iodine molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of iodine.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iodine molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:24860 NPO_1092 iodine molecular entity salt <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical compound which is formed by ionic interactions between cations and anions.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>salt</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:24866 NPO_1146 ionic compound salt monoatomic ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion which consists of a single atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>monoatomic ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:24867 NPO_1034 monoatomic ion ion <ncicp:ComplexDefinition><ncicp:def-definition>A chemical entity which carries a net electric charge.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:24870 NPO_546 [definition source]: ChEBI ion iron molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of iron.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iron molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:24873 NPO_1134 iron molecular entity isoleucine <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH(CH3)-CH2-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>isoleucine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:24898 Ile NPO_902 isoleucine isoprenoid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any lipid which is formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>isoprenoid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:24913 NPO_387 isoprenoid leucine 2-amino-4-methylpentanoic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-CH(CH3)-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>leucine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:25017 Leu NPO_285 leucine lysine 2,6-diaminohexanoic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-CH2-CH2-CH2-NH2)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lysine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:25094 Lys NPO_265 lysine manganese molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of manganese.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>manganese molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:25154 NPO_1136 manganese molecular entity mercury molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of mercury.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mercury molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:25196 NPO_1125 mercury molecular entity metal cation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic cation of a metal.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>metal cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:25213 NPO_1052 metal cation mitomycin <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quinone which is an aziridine-containing compound isolated from Streptomyces lavendulae.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mitomycin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:25357 NPO_352 mitomycin homoatomic molecule <ncicp:ComplexDefinition><ncicp:def-definition>A molecule which consists of atoms of the same element.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>homoatomic molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:25362 NPO_1028 homoatomic molecule molybdenum molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of molybdenum.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molybdenum molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:25370 NPO_1127 molybdenum molecular entity monoatomic monocation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic cation which has ionic charge 1+.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>monoatomic monocation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:25414 NPO_1054 monoatomic monocation monoatomic polycation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic cation which has ionic charge greater than 2+.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>monoatomic polycation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:25430 NPO_1063 monoatomic polycation oligosaccharide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A compound in which monosaccharide units are joined by glycosidic linkages. The term is commonly used to refer to a defined structure as opposed to a polymer of unspecified length or a homologous mixture. When the linkages are of other types the compounds are regarded as oligosaccharide analogues.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>oligosaccharide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:25679 NPO_680 [definition source]: CHEBI oligosaccharide organic anion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion which is organic.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>organic anion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:25696 NPO_1037 organic anion organic cation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cation which is organic.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>organic cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:25697 NPO_1041 organic cation ether <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ether is an organic compound in which an oxygen atom is covalently bound to two carbon atoms. It has the structure R-O-R', where R, R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ether</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:25698 NPO_230 ether organic ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion which is organic.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>organic ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:25699 NPO_1031 organic ion oxide <ncicp:ComplexDefinition><ncicp:def-definition>A chemical compound of oxygen with other chemical elements.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:25741 NPO_1147 oxide oxygen molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of oxygen.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>oxygen molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:25806 NPO_1099 oxygen molecular entity phosphorus molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of phosphorus.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>phosphorus molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:26082 NPO_1095 phosphorus molecular entity polyketide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A ketone which is a natural compound containing alternating carbonyl and methylene groups ('?-polyketones'), biogenetically derived from repeated condensation of acetyl coenzyme A (via malonyl coenzyme A); or another compound derived from it by further condensations.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polyketide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:26188 NPO_789 polyketide amidine <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amidine is an organic compound which is derived from an oxoacid RnE(=O)OH by replacing the hydroxyl group by an amino group and the oxo group by =NR. R stands for a hydrogen atom or organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>amidine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:2634 NPO_309 amidine pteridine compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic heterobicyclic compound which is composed partly or wholly of a pteridine ring system (a pyrimidine ring fused with a pyrazine ring).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>pteridine compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:26373 NPO_900 pteridine compound pterin <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A pterin compound which is wholly composed of a pteridine ring system, in which the pyrimidine ring has a carbonyl oxygen and an amino group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>pterin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:26374 NPO_550 pterin pterin compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A pteridine compound which is wholly or partly composed of a pteridine ring system in which the pyrimidine ring has a carbonyl oxygen and an amino group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>pterin compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:26375 NPO_693 pterin compound selenium molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of selenium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>selenium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:26628 NPO_1100 selenium molecular entity silicon molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of silicon.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>silicon molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:26677 NPO_1109 silicon molecular entity sulfur molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of sulfur.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sulfur molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:26835 NPO_1101 sulfur molecular entity technetium molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of technetium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>technetium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:26865 NPO_1137 technetium molecular entity terpenoid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any natural product and related compound formally derived from isoprene units. They may contain oxygen in various functional groups. This class is subdivided according to the number of carbon atoms in the same manner as are terpenes. The skeleton of terpenoids may differ from strict additivity of isoprene units by the loss or shift of a fragment, generally a methyl group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>terpenoid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:26873 NPO_381 terpenoid monoatomic tetracation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic polycation which has ionic charge 4+.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>monoatomic tetracation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:26937 NPO_1065 monoatomic tetracation threonine <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH(OH)-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>threonine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:26986 NPO_913 Thr threonine tin molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of tin.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tin molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:27008 NPO_1110 tin molecular entity monoatomic trication <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic polycation which has ionic charge 3+.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>monoatomic trication</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:27153 NPO_1064 monoatomic trication organic heterobicyclic compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic heterocyclic compound, which has two rings.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>organic heterobicyclic compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:27171 NPO_454 organic heterobicyclic compound valine 2-amino-3-methylbutanoic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2(CH3)-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>valine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:27266 NPO_964 Val valine vanadium molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of vanadium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>vanadium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:27275 NPO_1144 vanadium molecular entity zinc molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of zinc.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>zinc molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:27364 NPO_1123 zinc molecular entity folic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A pterin compound which contains para-aminobenzoic acid and L-glutamate unit conjugated with the pterin structure.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>folic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:27470 NPO_422 folic acid histidine 2-amino-3-(1H-imidazol-4-yl)propanoic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2c1c[nH]cn1)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>histidine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:27570 His NPO_329 histidine pteridine <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A pteridine compound in which a pyrimidine ring is fused with a pyrazine ring. It has the structure c1cnc2ncncc2n1.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>pteridine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:27601 NPO_289 pteridine tryptophan <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(Cc1c[nH]c2ccccc12)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tryptophan</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:27897 NPO_783 Trp tryptophan cisplatin <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A platinum compound in which the platinum atom is complexed with two ammonia groups and two chlorine atoms.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cisplatin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:27899 NPO_608 anticancer drug that induces breakage of DNA helix cisplatin phenylalanine 2-amino-3-phenylpropanoic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-c1ccccc1)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>phenylalanine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:28044 NPO_139 Phe phenylalanine glutamine 2,5-diamino-5-oxopentanoic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2CH2C(NH2)=O)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>glutamine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:28300 NPO_930 glutamine lactic acid 2-hydroxypropanoic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound which has the formula CH3CH(OH)C(OH)=O.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lactic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:28358 NPO_1557 alpha-hydroxypropanoic acid lactic acid doxorubicin 14-hydroxydaunorubicine <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anthracycline which is (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-?-L-lyxo-hexopyranoside. It has a parent hydride, tetracene, and has substructures that classify it as a deoxy hexoside, and a quinone.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>doxorubicin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:28748 NPO_788 adriamycin anticancer drug that inhibits protein activity related to DNA synthesis doxorubicin chlorambucil 1 <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of nitrogen mustard and an organochlorine compound.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chlorambucil</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:28830 NPO_346 anticancer drug that induces breakage of DNA helix chlorambucil arginine 2-amino-5-(carbamimidamido)pentanoic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-CH2-CH2-NH-C(NH2)=NH)-C(OH)=OH</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>arginine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Arg CHEBI:29016 NPO_875 arginine iron (2+) ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic dication of iron.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iron (2+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:29033 NPO_1057 iron (2+) ion iron (3+) ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic trication of iron.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iron (3+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:29034 NPO_1069 iron (3+) ion zinc (2+) ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic dication of zinc.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>zinc (2+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:29105 NPO_1053 zinc (2+) ion thiol <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thiol is an organic compound which is characterized by the presence of a sulfhydryl group. It has the structure R-SH, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thiol</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:29256 NPO_465 mercaptan sulfhydryl compound thiol disulfanedyl group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -S-S-. The group is characteristic of an organic disulfide molecule wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>disulfanedyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:29826 NPO_884 disulfanedyl group sulfhydryl group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -SH. The group is characteristic of a thiol molecule wherein it is attached to an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sulfhydryl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:29917 It is a substituent group from hydrogen sulfide. NPO_910 sulfhydryl group thiol group diazo group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which is a substituent group from diazene, and has the structure =[N+]=[N-]. The group is characteristic of a diazo compound wherein it is attached to an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>diazo group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:30105 NPO_462 diazo group monoatomic dication <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic cation which has ionic charge 2+.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>monoatomic dication</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:30412 NPO_1055 monoatomic dication astatide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion of astatine.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>astatide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:30417 NPO_1050 astatide molybdenum (5+) ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic pentacation of molybdenum.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molybdenum (5+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:30511 NPO_1073 molybdenum (5+) ion silicon dioxide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of silicon in which a silicon atom covalently bonded (double bond) with two oxygen atoms.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>silicon dioxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:30563 NPO_1372 silica silicon dioxide silicon (4+) ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic tetracation of silicon.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>silicon (4+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:30584 NPO_1070 silicon (4+) ion alcohol <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alcohol is an organic hydroxy compound in which a hydroxyl group is attached to a saturated carbon atom. It has the general structure OH-C-([*])([*])[*].</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>alcohol</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:30879 NPO_624 alcohol carboplatin <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A platinum compound in which the platinum atom is complexed with two ammonia groups and a cyclobutane-dicarboxyl residue.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carboplatin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:31355 NCIT: C1282 NPO_603 anticancer drug that induces breakage of DNA helix carboplatin oxaliplatin <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A platinum compound in which the platinum atom is complexed with 1,2-diaminocyclohexane (DACH) and with an oxalate bidentate ligand.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>oxaliplatin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:31941 NCIT:C1181 NPO_749 anticancer drug that induces breakage of DNA helix oxaliplatin secondary amine <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A secondary amine is an amine which is formally derived from ammonia by replacing two hydrogen atoms by hydrocarbyl groups, and it is characterized by the presence of a secondary amine group. It has the structure R-NH-R', where R,R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>secondary amine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:32863 NPO_805 secondary amine tertiary amine <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A tertiary amine is an amine which is formally derived from ammonia by replacing three hydrogen atoms by hydrocarbyl groups, and it is characterized by the presence of a tertiary amine group. It has the structure R-N(-R")-R', where R,R' and R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tertiary amine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:32876 NPO_832 tertiary amine primary amine <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A primary amine is an amine which is formally derived from ammonia by replacing one hydrogen atom by a hydrocarbyl group, and it is characterized by the presence of a primary amine group. It has the structure R-NH2, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>primary amine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:32877 NPO_947 primary amine amine <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amine is an organic compound which is formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups, and it is thus characterized by the presence of a primary or secondary or tertiary amine groups. It has the structure R-NH2 or R-NH-R' or R-N(-R")-R', where R, R' and R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>amine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:32952 NPO_143 amine amide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide is an organic compound formally derived from an oxoacid by replacing an acidic hydroxyl group of the oxoacid by an amino or substituted amino group. It is characterized by the presence of an "amide group."</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>amide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:32988 NPO_769 amide vanadium 5(+) ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic pentacation of vanadium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>vanadium 5(+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33003 NPO_1072 vanadium 5(+) ion monoatomic entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which consists of a single atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>monoatomic entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33238 NPO_1026 monoatomic entity coordination compound <ncicp:ComplexDefinition><ncicp:def-definition>A compound which consists of a central atom (usually metallic) to which is attached a surrounding array of other groups of atoms.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>coordination compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33240 NPO_1139 coordination compound organic functional class <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound or molecule which is characterized by the presence of a functional group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>organic functional class</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33244 NPO_202 organic functional class inorganic group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any substituent group which does not contain carbon.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inorganic group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33246 NPO_1567 inorganic group hydrocarbyl group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrocarbyl group is a univalent substituent group formed by removing a hydrogen atom from a hydrocarbon.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrocarbyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33248 NPO_559 hydrocarbyl group homoatomic molecular entity <ncicp:ComplexDefinition><ncicp:def-definition>A polyatomic entity which consists of a single element.</ncicp:def-definition><ncicp:Definition_Review_Date>111020</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>homoatomic molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1025 homoatomic molecular entity polyatomic anion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion which consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polyatomic anion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33273 NPO_1038 polyatomic anion heteroorganic compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A heteroorganic compound is an organic compound in which carbon atoms or organic groups are bonded directly to one or more heteroatoms.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>heteroorganic compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33285 NPO_293 heteroorganic compound heteroorganic entity heteroorganic molecule alkali metal molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of an alkali metal.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>alkali metal molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33296 NPO_1081 alkali metal molecular entity alkaline earth molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of an alkaline earth metal.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>alkaline earth molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33299 NPO_1080 alkaline earth molecular entity pnictogen molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a Group-15 element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>pnictogen molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33302 NPO_1085 pnictogen molecular entity chalogen molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a Group-16 element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chalogen molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33304 NPO_1086 chalogen molecular entity tellurium molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of tellurium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tellurium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33305 NPO_1102 tellurium molecular entity carboxylic ester <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carboxylic ester is an organic compound which is characterized by the presence of an carboxylic ester group. It has the structure R-C(=O)-O-R', where R,R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carboxylic ester</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33308 NPO_790 carboxylic ester silicon oxide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of silicon.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>silicon oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33327 NPO_1371 silicon oxide aryl group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrocarbyl group which is derived from an arene by removal of a hydrogen atom from a ring carbon atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>aryl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33338 NPO_826 aryl group monoatomic pentacation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic polycation which has ionic charge 5+.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>monoatomic pentacation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33422 NPO_1066 monoatomic pentacation monoatomic hexacation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic polycation which has ionic charge 6+.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>monoatomic hexacation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33423 NPO_1067 monoatomic hexacation monoatomic monoanion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic anion which has ionic charge 1-.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>monoatomic monoanion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33429 NPO_1043 monoatomic monoanion rubidide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic monanion of rubidide.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>rubidide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33496 NPO_1051 rubidide alkali metal cation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic cation of alkali metal.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>alkali metal cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33504 NPO_1076 alkali metal cation alkaline earth metal cation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monatomic cation of an alkaline earth metal.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>alkaline earth metal cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33513 NPO_1077 alkaline earth metal cation carboxylic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carboxylic acid is an organic acid compound which is characterized by the presence of a carboxyl group. It has the structure R-C(=O)-OH, where R denotes an organic group or a hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carboxylic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33575 NPO_574 carboxyl compound carboxylic acid prefix: Carboxy- suffix: -oic acid boron group molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a Group-13 element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>boron group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33581 NPO_1087 boron group molecular entity carbon group molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a Group-14 element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carbon group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33582 NPO_1088 carbon group molecular entity noble gas molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a noble gas.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>noble gas molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33583 NPO_1079 noble gas compound noble gas molecular entity germanium molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of germanium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>germanium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33584 NPO_1111 germanium molecular entity lead molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of lead.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>lead molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33585 NPO_1112 lead molecular entity aluminum molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of aluminum.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>aluminum molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33620 NPO_1105 aluminum molecular entity zinc group molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a zinc group (Group-12) element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>zinc group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33673 NPO_1114 zinc group molecular entity s-block molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a s-block element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>s-block molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33674 NPO_1082 s-block molecular entity p-block molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a p-block element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>p-block molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33675 NPO_1078 p-block molecular entity d-block molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a d-block element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>d-block molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33676 NPO_1083 d-block molecular entity hydride <ncicp:ComplexDefinition><ncicp:def-definition>A compound of hydrogen with other chemical elements.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33692 NPO_1148 hydride oxygen hydride <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydride containing one or more oxygen atoms.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>oxygen hydride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33693 NPO_1560 oxygen hydride biopolymer <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polymer formed by living organisms.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>biopolymer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33694 MESH: D001704 NPO_882 biomacromolecule biopolymer nucleic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polynucleotide which is present in living cells.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nucleic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33696 NPO_1001 nucleic acid ribonucleic acid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nucleic acid which is a derivative of DNA having ribose in place of deoxyribose, and uracil in place of thymine.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ribonucleic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33697 NPO_1003 RNA ribonucleic acid polyatomic cation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cation which consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polyatomic cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33702 NPO_1040 polyatomic cation alpha-aminoacid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aminoacid in which a primary amine group and a carboxyl group are attached to the same carbon atom, which is called the alpha?carbon..</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>alpha-aminoacid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33704 NPO_632 alpha-aminoacid aminoacid <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carboxylic acid containing one or more amine groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>aminoacid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33709 NPO_506 aminoacid chromium group molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a chromium group (Group-6) element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chromium group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33741 NPO_1115 chromium group molecular entity tungsten molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of tungsten.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tungsten molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33742 NPO_1128 tungsten molecular entity manganese group molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a manganese group (Group-7) element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>manganese group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33743 NPO_1116 manganese group molecular entity iron group molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a iron group (Group-8) element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iron group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33744 NPO_1117 iron group molecular entity copper group molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a copper group (Group-11) element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>copper group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33745 NPO_1118 copper group molecular entity vanadium group molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a vanadium group (Group-5) element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>vanadium group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33746 NPO_1119 vanadium group molecular entity nickel group molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a nickel group (Group-10) element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nickel group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33747 NPO_1120 nickel group molecular entity nickel molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of nickel.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nickel molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33748 NPO_1138 nickel molecular entity platinum molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of platinum.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>platinum molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33749 NPO_1140 platinum molecular entity cobalt group molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a cobalt group (Group-9) element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cobalt group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33767 NPO_1121 cobalt group molecular entity titanium group molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a titanium group (Group-4) element.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>titanium group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33768 NPO_1122 titanium group molecular entity organic hydroxy compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound which is characterized by the presence of one or more hydroxyl groups attached to carbon atoms.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>organic hydroxy compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33822 NPO_201 hydroxy compound organic hydroxy compound polymer <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polymer is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polymer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33839 MESH:D011108 NPO_364 [definition source]: CHEBI macromolecule polymer polymer molecule platinum coordination compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A coordination compound which contains platinum as the central atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>platinum coordination compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33862 NPO_297 platinum coordination compound rhodium molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of rhodium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>rhodium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33887 NPO_1129 rhodium molecular entity cobalt molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of cobalt.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cobalt molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33888 NPO_1130 cobalt molecular entity silver molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of silver.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>silver molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33964 NPO_1133 silver molecular entity gold molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of gold.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gold molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:33969 NPO_1132 gold molecular entity organonitrogen compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organonitrogen compound is a heteroorganic compound containing at least one carbon-nitrogen bond.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>organonitrogen compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:35352 NPO_503 organonitrogen compound sulfonamide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A sulfonamide is an amide derived from sulfonic acids, and thus characterized by the presence of a sulfonamide group. It has the structure R-S(=O)-NH2, R-S(=O)-NH-R' or R-S(=O)-N(-R")-R', where R,R',R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sulfonamide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:35358 NPO_908 sulfonamide carboxamidine <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amidine is an organic compound which is a derivative of a carboxylic acid, in which the hydroxy group is replaced by an amino group and the oxo group is replaced by =NR, and therefore, it has the structure R'-C(=N-R)-NH2, where R' denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carboxamidine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:35359 NPO_232 carboxamidine hydrazide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrazide is an organic compound or molecule which is derived from an oxoacid RkE(=O)l(OH)m (l ? 0) by replacing ?OH by ?N(-R)-N(-R')-R" (R,R',R" groups commonly denote H).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrazide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:35362 NPO_583 hydrazide carbohydrazide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carbohydrazide is a hyrazide derived from a carboxylic acid, and therefore has the structure R""-(C=O)-N(-R)-N(-R')-R", where R"" denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carbohydrazide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:35363 NPO_629 carbohydrazide organic disulfide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic disulfide is an organic compound which is characterized by the presence of a disulfanedyl group / disulfide bond. It has the structure R-S-S-R', where R,R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>organic disulfide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:35489 NPO_573 organic disulfide antineoplastic agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Anticancer drug, which brings about a cancer therapeutic effect by inhibiting or preventing the proliferation of neoplasms; i.e., it inhibits the maturation ,growth or spread of tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>antineoplastic agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:35610 NCIT: C274 NPO_777 antineoplastic agent antineoplastic drug ruthenium molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of ruthenium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ruthenium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:35734 NPO_1135 ruthenium molecular entity protein <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A biopolymer which is genetically encoded, the structure of which essentially consists of long chains of amino acid residues (derived from alpha aminoacids) connected by peptide bonds and have distinct and varied three-dimensional structures, usually containing alpha helices and beta sheets as well as looping and folded chains.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>protein</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:36080 NPO_982 protein quinone <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Cyclic ketone having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of ?CH= groups into ?C(=O)? groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>quinone</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:36141 NPO_774 quinone polyatomic entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polyatomic entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:36357 NPO_1023 polyatomic entity polyatomic ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion which consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polyatomic ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:36358 NPO_1033 polyatomic ion carbonyl compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carbonyl compound is an organic compound which is characterized by the presence of a carbonyl group, and therefore, has the structure R-(C=O)-R', where R, R" are organic groups or hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carbonyl compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:36586 NPO_527 carbonyl compound acid anhydride <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acid anhydride is an organic compound which is characterized by the presence of an acid anhydride group. It has the structure R-C(=O)-O-C(=O)-R', where R, R' stand for organic groups or hydrogen atoms.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>acid anhydride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:36606 NPO_883 acid anhydride organochlorine compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organochlorine compound is a compound containing at least one carbon-chlorine bond.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>organochlorine compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:36683 NPO_194 organochlorine compound inorganic ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion which is inorganic.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inorganic ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:36914 NPO_1032 inorganic ion inorganic cation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cation which is inorganic.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inorganic cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:36915 NPO_1042 inorganic cation cation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion which is positively charged.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:36916 NPO_1029 cation polonium molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of polonium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>polonium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:36917 NPO_1103 polonium molecular entity antimony molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of antimony.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>antimony molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:36919 NPO_1096 antimony molecular entity thallium molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of thallum.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thallium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37110 NPO_1106 thallium molecular entity gallium molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of gallium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gallium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37111 NPO_1107 gallium molecular entity indium molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of indium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>indium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37112 NPO_1108 indium molecular entity astatine molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of astatine.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>astatine molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37138 NPO_1093 astatine molecular entity organofluorine compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organofluorine compound is a compound containing at least one carbon-fluorine bond.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>organofluorine compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37143 NPO_698 organofluorine compound glucan <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A homopolysaccharide which is composed of glucose residues.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>glucan</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37163 MESH:D005936 NPO_676 glucan homopolysaccharide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polysaccharide, which is composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>homopolysaccharide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37164 NPO_896 [definition source]: CHEBI homoglycan homopolysaccharide bismuth molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of bismuth.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>bismuth molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37196 NPO_1098 bismuth molecular entity titanium molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of titanium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>titanium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37217 NPO_1142 titanium molecular entity zirconium molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of zirconium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>zirconium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37218 NPO_1143 zirconium molecular entity palladium molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of palladium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>palladium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37230 NPO_1141 palladium molecular entity gadolinium (2+) ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic dication of gadolinium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gadolinium (2+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37286 NPO_1060 gadolinium (2+) ion gadolinium (4+) ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic tetracation of gadolinium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gadolinium (4+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37294 NPO_1071 gadolinium (4+) ion diagnostic imaging agent <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which is used to enhance image formation of biological structures and functions for the detection and diagnosis of disease.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>diagnostic imaging agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37334 NCIT:C1966 NPO_681 diagnostic imaging agent image enhancement agent MRI contrast agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A contrast agent, which has magnetic properties and provides contrast in images captured using MRI.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>MRI contrast agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37335 MRI contrast agent NPO_581 contrast agent in magnetic resonance imaging radioactive imaging agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A contrast agent, which provides contrast in images captured using radioactive imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>radioactive imaging agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37336 NPO_361 radioactive imaging agent ultrasound contrast agent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A contrast agent, which provides contrast in images captured using ultrasound imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ultrasound contrast agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37337 NPO_250 contrast agent in ultrasound imaging ultrasound contrast agent ultrasound imaging contrast agent heteroatomic molecular entity <ncicp:ComplexDefinition><ncicp:def-definition>A polyatomic entity which consists of two or more chemical elements.</ncicp:def-definition><ncicp:Definition_Review_Date>111020</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>heteroatomic molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37577 NPO_1024 heteroatomic molecular entity nitrogen mustard <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of organonitrogen compound, which has two ?-haloalkyl groups bound to a nitrogen atom, as in (X?C2H2?C2H2)2NR.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nitrogen mustard</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37598 NPO_172 nitrogen mustard carboxamide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carboxamide is an amide derived from carboxylic acids. It is characterized by the presence of a carboxamide group. It has the structure R-C(=O)-NH2, R-C(=O)-NH-R' or R-C(=O)-N(-R")-R', where R,R',R" stands for organic groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carboxamide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37622 NPO_269 carboxamide protein kinase inhibitor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An enzyme inhibitor, which inhibits the activity of protein kinase.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>protein kinase inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37699 NCIT: C1404 NPO_436 inhibits phosphorylation in the signaling pathway, which regulates a variety of fundamental processes, such as cell growth, mitogenesis, metabolism, gene transcription, cell cycle control, and the immune response. protein kinase inhibitor fluorescein isothiocyanate <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound which is derived from fluorescein by replacing a hydrogen atom of the benzene ring (the one that does not contain the hydroxyl groups), with an amine-reactive isothiocyanate group.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluorescein isothiocyanate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:37926 FITC NPO_134 fluorescein isothiocyanate quinazoline compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quinazoline compound is a derivative of quinazoline.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>quinazoline compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:38530 NPO_386 quinazoline compound hydrazone <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrazone is an organic compound which is formally derived from aldehydes or ketones by replacing =O by =N-NH2 or =N-NH-R', and thus, characterized by a "hydrazone group." It has the structure R-C(=N-NH2)-R" or R-C(=N-NH-R')-R".</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrazone</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:38532 NPO_971 hydrazone conjugated protein <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A protein that contains a non-protein prosthetic group such as sugar, nucleic acid, lipid, or metal ion.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>conjugated protein</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:38560 NPO_578 [definition source]: L. G. Wade Jr. Organic Chemistry 3rd Edition conjugated protein diazo compound <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A diazo compound is an organic compound which is characterized by the presence of a diazo group. It has the structure R=[N+]=[N-], where R denotes an organic group..</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>diazo compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:39444 NPO_569 diazo compound cyclic ketone <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A ketone which is a cyclic compound containing one or more ketone groups.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cyclic ketone</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:3992 NPO_373 cyclic ketone cyclophosphamide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of nitrogen mustard.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cyclophosphamide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:4027 NPO_890 anticancer drug that induces breakage of DNA helix cyclophosphamide tamoxifen <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Tamoxifen is an organic compound, which has a parent hydride, stilbin; and which blocks the effects of the hormone estrogen in the body. It is used to prevent or delay the return of breast cancer or to control its spread.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tamoxifen</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:41774 NPO_254 modifies expression of specific genes tamoxifen idarubicin 4-Demethoxydaunorubicin <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anthracycline which is (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-?-L-lyxo-hexopyranoside.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>idarubicin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:42068 NPO_817 anticancer drug that inhibits protein activity related to DNA synthesis idarubicin aldehyde group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)H. The group is characteristic of an aldehyde wherein it is attached to the remaining part of the molecule via covalent bond with hydrogen or carbon atoms.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>aldehyde group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:42485 NPO_590 aldehyde group formyl group hydroxyl group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group, in which an oxygen atom is bonded to a hydrogen atom, and has the structure -OH. The group is characteristic of an organic hydroxy molecule wherein it is attached to a carbon atom via a single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydroxyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:43176 NPO_941 hydroxy group hydroxyl group prefix: hydroxy suffix: -ol methotrexate <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A pteridine compound has a pteridine substructure; which has functional parent, L-glutamic acid; which has other substructures that classify it a monocarboxylic acid amide and a dicarboxylic acid.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>methotrexate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> An antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities. Methotrexate binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis and, subsequently, inhibition of DNA and RNA syntheses. Methotrexate also exhibits potent immunosuppressant activity although the mechanism(s) of actions is unclear. CHEBI:44185 NCIT:C642 NPO_741 methotrexate paclitaxel <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A diterpenoid, which consists of a tetracyclic core called baccatin III, and an amide tail.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>paclitaxel</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:45863 MESH: D017239 NCIT:C1411 NPO_860 Paclitaxel is isolated from the bark of the Pacific yew tree. paclitaxel 5-fluorouracil 5-fluorouracil <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organofluorine compound, which has uracil as the funcitonal parent.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>5-fluorouracil</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:46345 NPO_365 anticancer drug that inhibits protein activity related to DNA synthesis mineral <ncicp:ComplexDefinition><ncicp:def-definition>A mineral is a naturally occurring chemical substance formed through geological processes that has a characteristic chemical composition, a highly ordered atomic structure and specific physical properties.</ncicp:def-definition><ncicp:Definition_Review_Date>111020</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mineral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:46662 NPO_1563 mineral phosphate mineral <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mineral which contains phosphate anions.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>phosphate mineral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:46723 NPO_1564 phosphate mineral solvent <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A liquid which can dissolve other substancees (solutes) without any change in their chemical composition.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>CHEBI</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>solvent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:46787 NPO_1831 solvent poly(ethylene glycol) <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polymer made by the polymerization of ethylene oxide.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>poly(ethylene glycol)</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:46793 NPO_444 PEG poly(ethylene glycol) carboxyl group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)-OH. The group is characteristic of carboxylic acid compounds, wherein it is attached to a hydrogen atom or a carbon atom by a single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>carboxyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:46883 NPO_838 carboxyl group halo group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -X, where 'X' denotes a halogen atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>halo group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:47854 NPO_135 halo group acryloyl group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)-CH=CH2, and the group is characteristic of acryloyl compounds.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>acryloyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:48077 NPO_215 acryloyl group anthracycline <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polyketide which has a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>anthracycline</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:48120 NPO_539 anthracycline angiogenesis inhibitor <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antineoplastic agent that slows down or prevents the formation and growth of blood or lymphatic vessels. In cancer therapy, angiogenesis inhibitors target blood vessels that supply tumors, thereby inhibiting tumor growth.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>angiogenesis inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:48422 MESH: D020533 NCIT: C1742 NPO_595 angiogenesis antagonist angiogenesis inhibitor cyano group <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cyano group is a substituent group from hydrogen cyanide, and has the structure -C#N.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cyano group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:48819 NPO_588 cyano group cobalt (2+) ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic dication of cobalt.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cobalt (2+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:48828 NPO_1059 cobalt (2+) ion etoposide (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-?-D-glucopyranoside <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound or molecule, which has a functional parent, podophyllotoxin; which has substructure that classifies it as a beta-D-glucoside.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>etoposide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:4911 NPO_168 etoposide molybdenum (6+) ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic hexacation of molybdenum.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molybdenum (6+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:49446 NPO_1074 molybdenum (6+) ion silver (1+) ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monatomic monocation of silver.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>silver (1+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:49468 NPO_1062 silver (1+) ion gold (1+) ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic monocation of gold.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gold (1+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:49482 NPO_1061 gold (1+) ion europium (2+) ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic dication of europium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>europium (2+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:49588 NPO_1058 europium (2+) ion gadolinium (3+) ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic trication of gadolinium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gadolinium (3+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:49618 NPO_1068 gadolinium (3+) ion gefitinib <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of quinazoline compound.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gefitinib</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:49668 Iressa NPO_123 ZD-1839 drug directed against intracellular domain of membrane receptor gefitinib removed 'has_role some epidermal growth factor receptor tyrosine kinase inhibitor' tungsten (6+) ion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic hexacation of tungsten.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tungsten (6+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:49955 NPO_1075 tungsten (6+) ion monoatomic tetraanion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic anion which has ionic charge -4.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>monoatomic tetraanion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:50086 NPO_1044 monoatomic tetraanion iron (III) oxide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iron oxide with the chemical formula Fe2O3.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iron (III) oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:50819 NPO_1149 ferric oxide iron (III) oxide iron (II) oxide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iron oxide with the chemical formula FeO.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iron (II) oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:50820 NPO_1150 ferrous oxide iron (II) oxide iron (II,III) oxide <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iron oxide with the chemical formula Fe3O4.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>iron (II,III) oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:50821 NPO_1151 ferrosoferric oxide iron (II,III) oxide nitrogen molecular entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of nitrogen.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nitrogen molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:51143 NPO_1097 nitrogen molecular entity apatite <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phosphate mineral with the general formula Ca5(PO4)3X where X = OH, F or Cl.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>apatite</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:52254 NPO_1565 apatite hydroxyapatite <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phosphate mineral with the formula Ca5(PO4)3(OH).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydroxyapatite</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> CHEBI:52255 NPO_1566 hydroxyapatite hydroxylapatite infrared spectroscopy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An absorption spectroscopic technique in which a beam of infrared light is used to irradiate a sample. The IR absorption spectra obtained with this technique, is used to identify compounds or investigate sample composition based on the correlation of absorption bands in the spectrum of the unknown compound with known absorption frequencies for specific types of bonds.</ncicp:def-definition><ncicp:Definition_Review_Date>100611</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>infrared spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> FIX:0000015 IR spectroscopy NPO_1473 The technique is based on the fact that molecules have specific frequencies at which they rotate or vibrate corresponding to discrete energy levels (vibrational modes). infrared spectroscopy ultraviolet/visible spectroscopy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An absorption spectroscopic technique in which the irradiating light has wavelengths within the ultraviolet and visible regions of the electromagnetic spectrum.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>ultraviolet/visible spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> FIX:0000016 NPO_1475 UV-Vis spectroscopy ultraviolet/visible spectroscopy x-ray photoelectron spectroscopy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which is carried out in vaccum, and is used to estimate the elemental composition and chemical state of the elements on the surface of a material by irradiating the material surface with a beam of soft monochromatic (magnesium/aluminum) X-rays and measuring the kinetic energy of photoelectrons emitted from the core orbitals of the surface elements within a few nm from the material surface.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>x-ray photoelectron spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> ESCA Electron Spectroscopy for Chemical Analysis FIX:0000041 NCIT:C78871 NPO_1471 Photoelectrons are collected and analyzed by the XPS instrument to produce a spectrum of emission intensity versus electron binding energy. Since each element has a unique set of binding energies, XPS can be used to identify the elements on the surface. Also, peak areas at nominal binding energies can be used to quantify concentration of the elements. Small shifts in these binding energies (chemical shifts) provide powerful information about sample chemical states and short-range chemistry . XPS [definition: based on NCIT, http://encyclopedia.thefreedictionary.com, http://www.chem.umd.edu/facility/xps.php] x-ray photoelectron spectroscopy chromatography <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A separation technique for separation of mixtures, in which a mixture dissolved in a mobile liquid or gas medium, is passed through a stationary adsorbing medium to separate the components based on differential affinities of the components for the mobile medium and for the stationary medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chromatography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> FIX:0000053 NPO_1458 [definition adapted from NCIT, WordNet, http://encyclopedia.thefreedictionary.com/chromatography] chromatography Raman spectroscopy <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which is based on the detection of inelastically scattered monochromatic light from a laser in the visible, near infrared, or near ultraviolet range, by a substance (or sample under investigation). A laser beam of a given wavelength is used to irradiate a spot on the sample under investigation. The inelastically scattered light ( photons scattered at lower frequencies or higher wavelengths compared to that of the incident photons (Raman effect)), contains information about the energies of molecular vibrations and rotations, and these depend on the particular atoms or ions that comprise the molecule, the chemical bonds connect them, the symmetry of their molecule structure, and the physico-chemical environment where they reside.</ncicp:def-definition><ncicp:Definition_Review_Date>100527</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Raman spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> FIX:0000058 NCIT:C17157 NPO_1472 Raman spectroscopy [definition: adapted from http://epsc.wustl.edu/haskin-group/Raman/faqs.htm, http://encyclopedia.thefreedictionary.com] gas chromatography <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chromatography technique in which the mobile phase is a gas.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gas chromatography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> FIX:0000098 NPO_1460 gas chromatography contact atomic force microscopy <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atomic force microscopy technique in which the tip of the cantilever is in contact with the sample's surface. In the contact mode, the overall force between the tip and the surface is repulsive and it is kept constant during scanning by maintaining a constant deflection, and therefore constant height above the surface.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>contact atomic force microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> FIX:0000116 NPO_1448 [definition: adapted from http://en.wikipedia.org, http://www.nanoscience.com/education/AFM.html] contact AFM contact atomic force microscopy non contact atomic force micrsocopy <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atomic force microscopy technique in which the tip of the cantilever is not in contact with sample's surface. In non contact mode, the overall force between the tip and the surface is attractive. The cantilever is oscillated at a frequency slightly above its resonance frequency where the amplitude of oscillation is typically a few nanometers (<10 nm). The van der Waals forces, which are strongest from 1 nm to 10 nm above the surface, or any other long range force which extends above the surface acts to decrease the resonance frequency of the cantilever. This decrease in resonance frequency combined with the feedback loop system maintains a constant oscillation amplitude or frequency by adjusting the average tip-to-sample distance. Measuring the tip-to-sample distance at each (x,y) data point allows the scanning software to construct a topographic image of the sample surface.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>non contact atomic force micrsocopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> FIX:0000117 NC-AFM NPO_1449 non contact atomic force micrsocopy magnetic force microscopy <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A non contact atomic force microscopy technique based on the use of magnetic force microscope.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>magnetic force microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> FIX:0000118 NPO_1450 magnetic force microscopy near-infrared spectroscopy <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An infrared spectroscopy where the beam of light that irradiates the sample has wavelengths within the near-infrared region of the electromagnetic spectrum.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>near-infrared spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> FIX:0000321 NIR spectroscopy NPO_1474 near-infrared spectroscopy light scattering <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A technique based on the disperson of light or electromagnetic radiation into a range of directions by virtue of its interaction with a material medium through which it passes.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>light scattering</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> FIX:0000402 NCIT:C62323 NPO_1466 [definition: adapted from NCIT] light scattering light scattering technique chromatography by mobile phase state <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chromatography technique classified based on the phase of the mobile medium.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chromatography by mobile phase state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> FIX:0000607 NPO_1459 chromatography by mobile phase state chromatography by physical state of the mobile phase liquid chromatography <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chromatography technique in which the mobile phase is a liquid.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>liquid chromatography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> FIX:0000608 LC NPO_1461 liquid chromatography chromatography by separation mechanism <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chromatography technique classified based on the mechanism of separation.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chromatography by separation mechanism</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> FIX:0000610 NPO_1463 chromatography by separation mechanism size-exclusion chromatography <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chromatography technique which uses porous gels to separate solute molecules or particles based on size.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>size-exclusion chromatography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> FIX:0000626 GPC NCIT:C16433 NPO_1464 SEC gel filtration chromatography gel permeation chromatography size-exclusion chromatography high pressure liquid chromatography <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A liquid chromatography technique in which the sample is forced by a liquid (mobile phase) at high pressure, through a column that is packed with a solid stationary phase.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>high pressure liquid chromatography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> FIX:0000630 HPLC NCIT: C16434 NPO_1462 high performance liquid chromatography high pressure liquid chromatography capillary electrophoresis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electrophoresis technique, in which a sample is introduced into a capillary tube and the components are separated by the application of high voltage. Due to the large surface to volume ratio, cooling is more efficient, allowing use of higher voltages. As a result, separation occurs more quickly and sensitivity is increased. The technique allows for separation of proteins, nucleic acids, and carbohydrates.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>capillary electrophoresis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> FIX:0000836 NCIT:C17637 NPO_1457 capillary electrophoresis angiogenesis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>angiogenesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0001525 NPO_657 angiogenesis blood vessel formation from pre-existing blood vessels molecular function <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Elemental activity, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molecular function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0003674 NPO_362 [source]: GO molecular activity molecular function nucleic acid binding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively and non-covalently with any nucleic acid.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nucleic acid binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0003676 NPO_1620 nucleic acid binding DNA binding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any molecular function by which a gene product interacts selectively with DNA (deoxyribonucleic acid).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>DNA binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DNA binding GO:0003677 NPO_1621 microtubule/chromatin interaction plasmid binding antigen binding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>antigen binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0003823 NPO_959 antigen binding enzyme activity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. [source: ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>enzyme activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0003824 NPO_584 catalytic activity enzyme activity DNA topoisomerase activity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>DNA topoisomerase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DNA topoisomerase activity GO:0003916 NPO_700 DNA topoisomerase type II activity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>DNA topoisomerase type II activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DNA topoisomerase (ATP-hydrolyzing) activity DNA topoisomerase type II activity GO:0003918 NPO_450 dihydrofolate reductase activity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dihydrofolate reductase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0004146 NPO_593 dihydrofolate reductase activity protein kinase activity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. [source: MetaCyc:PROTEIN-KINASE-RXN]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>protein kinase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0004672 NPO_953 protein kinase activity protein tyrosine kinase activity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. [source: EC:2.7.10]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>protein tyrosine kinase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0004713 NPO_217 protein tyrosine kinase activity thymidylate synthase activity 5,10-methylenetetrahydrofolate:dUMP C-methyltransferase activity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP. [source: EC:2.1.1.45]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thymidylate synthase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0004799 NPO_820 TMP synthetase activity dTMP synthase activity methylenetetrahydrofolate:dUMP C-methyltransferase activity thymidylate synthase activity thymidylate synthetase activity receptor activity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Combining with an extracellular or intracellular messenger to initiate a change in cell activity.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>receptor activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0004872 NPO_1593 receptor activity receptor binding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. [source: GOC:bf, GOC:ceb, ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>receptor binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0005102 NPO_780 receptor binding epidermal growth factor receptor binding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with the epidermal growth factor receptor. [source: GOC:ai]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>epidermal growth factor receptor binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> EGF receptor binding EGFR binding GO:0005154 NPO_165 TGF-alpha receptor binding epidermal growth factor receptor binding transforming growth factor alpha receptor binding binding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0005488 NPO_547 binding protein binding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). [source: GOC:go_curators]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>protein binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0005515 NPO_170 protein amino acid binding protein binding cellular component <ncicp:ComplexDefinition><ncicp:def-definition>A material entity, which is the part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>Gene Ontology (GO)</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cellular component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0005575 NPO_1008 cellular component extracellular space <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [source: GO]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>extracellular space</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> FMA:70022 GO:0005615 NPO_1580 extracellular space intercellular space cell <ncicp:ComplexDefinition><ncicp:def-definition>A material entity which is the basic structural and functional unit of all organisms. It includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0005623 NPO_1009 cell DNA metabolic process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. [source: ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>DNA metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DNA metabolic process DNA metabolism GO:0006259 NPO_1014 DNA replication <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>DNA replication</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DNA biosynthesis DNA replication DNA synthesis GO:0006260 NPO_142 DNA modification <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>DNA modification</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DNA modification GO_0006304 NPO_1624 DNA alkylation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>DNA alkylation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DNA alkylation GO:0006305 NPO_1625 transcription <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The synthesis of either RNA on a template of DNA or DNA on a template of RNA. [source: ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>transcription</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0006350 NPO_1015 transcription DNA-dependent transcription <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The synthesis of RNA on a template of DNA.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>DNA-dependent transcription</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> DNA-dependent transcription GO:0006351 NPO_840 regulation of DNA-dependent transcription <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that modulates the frequency, rate or extent of DNA-dependent transcription.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>regulation of DNA-dependent transcription</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0006355 NPO_1650 regulation of DNA-dependent transcription endocytosis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Cellular uptake of extracellular materials within membrane-limited vacuoles or microvesicles.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>endocytosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0006897 NCIT: C16544 NPO_299 [definition source]: NCI_Thesaurus endocytosis phagocytosis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The process whereby phagocytes engulf external particulate material. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>phagocytosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0006909 NPO_1368 phagocytosis apoptosis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface. [source: GOC:go_curators, ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>apoptosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0006915 NPO_548 apoptosis apoptotic programmed cell death programmed cell death by apoptosis mitosis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Progression through mitosis, the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother. [source: GOC:ma, ISBN:0198547684]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mitosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0007067 NPO_712 mitosis cell adhesion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. [source: GOC:hb, GOC:pf]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cell adhesion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0007155 NPO_997 cell adhesion negative regulation of cell adhesion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process that stops, prevents or reduces the frequency, rate or extent of cell adhesion.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>negative regulation of cell adhesion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> An inhibition which involves interference with, or restraint of, the activities of biologic molecules, biologic complexes, or subcellular components that promote the adherence of cells to surfaces or to other cells. [NCIT definition] GO:0007162 NCIT:C40708 NPO_1635 cell adhesion inhibition down regulation of cell adhesion down-regulation of cell adhesion downregulation of cell adhesion inhibition of cell adhesion negative regulation of cell adhesion blood coagulation <ncicp:ComplexDefinition><ncicp:def-definition>For definition, please refer to the Gene Ontology (v. 1.1.2341).</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>GO (v. 1.1.2341)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>blood coagulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1988 blood coagulation cytoskeletal protein binding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton. [source: GOC:mah]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cytoskeletal protein binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0008092 NPO_984 cytoskeletal protein binding biological process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>biological process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0008150 NPO_427 [source]: GO biological process physiological process metabolic process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. [source: GOC:go_curators, ISBN:0198547684]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0008152 NPO_1004 metabolic process metabolism negative regulation of DNA replication <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>negative regulation of DNA replication</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0008156 NPO_1636 down regulation of DNA replication down-regulation of DNA replication downregulation of DNA replication inhibition of DNA replication negative regulation of DNA replication cell death <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. [source: GOC:ems]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cell death</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0008219 NPO_995 cell death biosynthetic process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. [source: GOC:curators, ISBN:0198547684]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0009058 NPO_1005 anabolism biosynthesis biosynthetic process cellular process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [source: GOC:go_curators, GOC:isa_complete]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cellular process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0009987 NPO_994 cellular physiological process cellular process programmed cell death <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Cell death resulting from activation of endogenous cellular processes. [source: GOC:lr]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>programmed cell death</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0012501 NPO_996 programmed cell death tubulin binding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with monomeric or multimeric forms of tubulin, including microtubules. [source: GOC:clt]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tubulin binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0015631 NPO_814 tubulin binding RNA metabolic process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. [source: ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>RNA metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0016070 NPO_1016 RNA metabolic process RNA metabolism cell-cell adhesion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The attachment of one cell to another cell via adhesion molecules. [source: GOC:hb]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cell-cell adhesion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0016337 NPO_479 cell-cell adhesion negative regulation of angiogenesis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>negative regulation of angiogenesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0016525 NPO_1646 angiogenesis inhibition down regulation of angiogenesis down-regulation of angiogenesis downregulation of angiogenesis inhibition of angiogenesis negative regulation of angiogenesis cell cycle process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. [source: GOC:isa_complete]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cell cycle process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0022402 NPO_998 cell cycle process cell cycle phase <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events. [source: GOC:isa_complete]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cell cycle phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0022403 NPO_999 cell cycle phase estrogen receptor binding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with an estrogen receptor.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>estrogen receptor binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0030331 NPO_575 estrogen receptor binding developmental process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. [source: GOC:isa_complete]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>developmental process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0032502 NPO_992 developmental process RNA biosynthetic process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. [source: GOC:mah]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>RNA biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0032774 NPO_1017 RNA anabolism RNA biosynthesis RNA biosynthetic process RNA formation RNA synthesis cellular biopolymer metabolic process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells. [source: GOC:mah]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cellular biopolymer metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0034960 NPO_1012 cellular biopolymer metabolic process cellular biopolymer metabolism cellular biopolymer biosynthetic process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells. [source: GOC:mah]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cellular biopolymer biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0034961 NPO_1007 cellular biopolymer biosynthesis cellular biopolymer biosynthetic process nuclear hormone receptor binding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with a nuclear hormone receptor, a ligand-dependent receptor found in the nucleus of the cell. [source: GOC:bf]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nuclear hormone receptor binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0035257 NPO_798 nuclear hormone receptor binding steroid hormone receptor binding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with a steroid hormone receptor. [source: GOC:bf]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>steroid hormone receptor binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0035258 NPO_958 steroid hormone receptor binding tumor necrosis factor biosynthetic process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis. [source: GOC:jl, PMID:10891884]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>tumor necrosis factor biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0042533 NPO_647 TNF alpha biosynthesis tumor necrosis factor alpha biosynthesis tumor necrosis factor anabolism tumor necrosis factor biosynthesis tumor necrosis factor biosynthetic process tumor necrosis factor synthesis inhibition of tumor necrosis factor biosynthetic process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inhibition of tumor necrosis factor biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0042536 NPO_1662 inhibition of tumor necrosis factor biosynthetic process alpha-tubulin binding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with the microtubule constituent protein alpha-tubulin. [source: GOC:jl]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>alpha-tubulin binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0043014 NPO_600 alpha-tubulin binding gamma-tubulin binding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with the microtubule constituent protein gamma-tubulin. [source: GOC:jl]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gamma-tubulin binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0043015 NPO_512 gamma-tubulin binding positive regulation of enzyme activity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the activity of an enzyme.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>positive regulation of enzyme activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0043085 NPO_1655 activation of enzyme activity positive regulation of enzyme activity stimulation of enzyme activity up regulation of enzyme activity up-regulation of enzyme activity upregulation of enzyme activity enzyme inhibition <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of an enzyme.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>enzyme inhibition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0043086 NPO_1632 REX:0000233 down regulation of enzyme activity enzyme inhibition inhibition of enzyme activity biopolymer metabolic process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins. [source: GOC:jl, http://en.wikipedia.org/]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>biopolymer metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0043283 NPO_1013 biopolymer metabolic process biopolymer metabolism biopolymer biosynthetic process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins. [source: GOC:jl, http://en.wikipedia.org/]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>biopolymer biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0043284 NPO_1006 biopolymer biosynthesis biopolymer biosynthetic process biopolymer formation biopolymer synthesis negative regulation of molecular function <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>negative regulation of molecular function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0044092 NPO_1654 negative regulation of molecular function positive regulation of molecular function <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>positive regulation of molecular function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0044093 NPO_1644 positive regulation of molecular function cellular metabolic process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways by which individual cells transform chemical substances. [source: GOC:go_curators]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cellular metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0044237 NPO_1011 cellular metabolic process cellular metabolism cellular biosynthetic process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. [source: GOC:jl]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cellular biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0044249 NPO_1010 cellular biosynthetic process positive regulation of DNA replication <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of DNA replication.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>positive regulation of DNA replication</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0045740 NPO_1648 activation of DNA replication positive regulation of DNA replication stimulation of DNA replication up regulation of DNA replication up-regulation of DNA replication upregulation of DNA replication positive regulation of angiogenesis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>positive regulation of angiogenesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0045766 NPO_1645 positive regulation of angiogenesis positive regulation of cell adhesion <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of cell adhesion.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>positive regulation of cell adhesion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0045785 NPO_1643 positive regulation of cell adhesion negative regulation of mitosis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>negative regulation of mitosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0045839 NPO_1640 down regulation of mitosis down-regulation of mitosis downregulation of mitosis inhibition of mitosis negative regulation of mitosis positive regulation of mitosis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of mitosis.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>positive regulation of mitosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0045840 NPO_1639 activation of mitosis positive regulation of mitosis stimulation of mitosis up regulation of mitosis up-regulation of mitosis upregulation of mitosis negative regulation of DNA-dependent transcription <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>negative regulation of DNA-dependent transcription</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0045892 NPO_1652 down regulation of DNA-dependent transcription down-regulation of DNA-dependent transcription downregulation of DNA-dependent transcription inhibition of DNA-dependent transcription negative regulation of DNA-dependent transcription positive regulation of DNA-dependent transcription <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>positive regulation of DNA-dependent transcription</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0045893 NPO_1651 activation of DNA-dependent transcription positive regulation of DNA-dependent transcription stimulation of DNA-dependent transcription up regulation of DNA-dependent transcription up-regulation of DNA-dependent transcription upregulation of DNA-dependent transcription folic acid metabolic process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>folic acid metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0046655 NPO_1629 folate metabolic process folate metabolism folic acid metabolic process folic acid metabolism beta-tubulin binding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with the microtubule constituent protein beta-tubulin. [source: GOC:krc]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>beta-tubulin binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0048487 NPO_793 beta-tubulin binding positive regulation of biological process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of biological process.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>positive regulation of biological process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0048518 NPO_1638 positive regulation of biological process negative regulation of biological process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of a biological process.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>negative regulation of biological process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0048519 NPO_1647 negative regulation of biological process anatomical structure formation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. [source: GOC:dph, GOC:jic]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>anatomical structure formation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0048646 NPO_993 anatomical structure formation formation of an anatomical structure regulation of biological process <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>regulation of biological process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0050789 NPO_1637 regulation of biological process regulation of physiological process cell division <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The process resulting in the physical partitioning and separation of a cell into daughter cells. [source: GOC:go_curators]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cell division</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0051301 NPO_545 cell division hormone receptor binding <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with a receptor for hormones. [source: GOC:ai]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hormone receptor binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0051427 NPO_499 hormone receptor binding regulation of molecular function <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>regulation of molecular function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0065009 NPO_1653 regulation of molecular function cellular necrosis <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cellular necrosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> GO:0070265 NPO_1369 cellular necrosis necrosis mobility <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity inhering in an object by virtue of its ability to move or be moved freely.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mobility</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1314 PATO:0000004 mobility velocity <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity inhering in an object by virtue of the rate of change of its position.</ncicp:def-definition><ncicp:Definition_Review_Date>100429</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>velocity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1316 PATO:0000008 speed velocity frequency <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The rate at which an event occurs or is repeated over a particular period of time.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>frequency</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1330 PATO:0000044 frequency size <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a bearer by virtue of its physical magnitude.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>size</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1225 PATO:0000117 size height <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 1-D extent quality which is equal to the vertical dimension of extension.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>height</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1229 PATO:0000119 height length <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 1-D extent quality which is equal to the distance between two points.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>length</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1227 PATO:0000122 length mass <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality that inheres in a bearer in proportion to the amount of matter it contains. It is the property of a substance that causes it to have weight in a gravitational field.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mass</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1169 PATO:0000125 mass weight <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A force inhering in an object with mass near a gravitational body.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>weight</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1218 PATO:0000128 weight temperature <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality of the thermal energy of a system.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>temperature</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1287 PATO:0000146 temperature viability <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity inhering in a bearer or a population, by virtue of the bearer's ability or inability to survive and develop normally or the number of surviving individuals in a given population.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>viability</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1342 PATO:0000169 viability photosensitive <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition inhering in a bearer by virtue of its exhibiting photosensitivity.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>photosensitive</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1348 PATO:0000547 photosensitive thickness <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 1-D extent quality which is equal to the dimension through an object as opposed to its length or width.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>thickness</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1230 PATO:0000915 thickness volume <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 3-D extent quality of the amount of 3-dimensional space an object occupies.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>volume</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1238 PATO:0000918 volume width <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 1-D extent quality which is equal to the distance from one side of an object to another side which is opposite.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>width</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1231 PATO:0000921 breadth width photosensitivity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition inhering to the bearer by virtue of its sensitivity to the action of radiant energy.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>photosensitivity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1347 PATO:0000927 photosensitivity physical quality <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality which exists through action of continuants at the physical level of organisation.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>physical quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1152 PATO:0001018 physical quality density <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A physical quality which inhers to the bearer by virtue of some influence exerted by its mass.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>density</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1273 PATO:0001019 density force <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity inhering in a object affecting its acceleration.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>force</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1166 PATO:0001035 force wavelength <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A wave parameter which is equal to the distance between repeating units of a wave pattern.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>wavelength</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1346 PATO:0001242 wavelength electromagnetic radiation quality <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in an object by virtue of how that object interacts with electromagnetic radiation.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>electromagnetic radiation quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1385 PATO:0001291 electromagnetic radiation quality luminous quality <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scalar optical quality which obtains by the magnitude of the light emitted by the bearer.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>luminous quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1387 PATO:0001296 luminous quality optical quality <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An EM radiation quality in which the EM radiation is within the fiat range of the spectrum visible deemed to be light.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>optical quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1386 PATO:0001300 optical quality area <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 2-D extent inhering in a bearer by virtue of its two dimensional extent.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>area</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1234 PATO:0001323 area diameter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality which is equal to the length of any straight line segment that passes through the center of a circle and whose endpoints are on the circular boundary.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>diameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1228 PATO:0001334 diameter mass density <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A density quality which is equal to the mass exerting an influence on a given volume.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mass density</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1274 PATO:0001353 mass density membrane potential <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a cell's plasma membrane by virtue of the electrical potential difference across it.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>membrane potential</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1301 PATO:0001462 membrane potential electric potential <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity that is equal to the potential energy per unit charge associated with a static (time-invariant) electric field, also called the electrostatic potential.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>electric potential</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1300 PATO:0001464 electric potential electrostatic potential sound quality <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a bearer by virtue of vibration, as perceived by the sense of hearing.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>sound quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1349 PATO:0001519 sound quality frequency of sound wave <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The frequency of transmitted vibrations.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>frequency of sound wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1350 PATO:0001520 frequency of sound frequency of sound wave speed of sound wave <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The speed at which sound travels in a given medium under specified conditions.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>speed of sound wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1352 PATO:0001522 speed of sound speed of sound wave velocity of sound wavelength of sound <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>The quotient of the speed of a sound wave divided by its frequency.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>wavelength of sound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1353 PATO:0001523 wavelength of sound depth <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 1-D extent downward or backward or inward.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>depth</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1232 PATO:0001595 depth specific volume <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality of the amount of 3-dimensional space a mass of substance occupies.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>specific volume</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1240 PATO:0001679 The reciprocal of density. specific volume molar volume <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality of the amount of 3-dimensional space a homogeneous substance containing 6.02 x 1023 atoms or molecules occupies.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molar volume</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1239 PATO:0001680 molar volume molar mass <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality that inheres in a homogeneous substance containing 6.02 x 1023 atoms or molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molar mass</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1170 PATO:0001681 molar mass magnetism <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity which is a property inhering in a material entity by virtue of its ability to exert an attractive or repulsive force on other material entities.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>magnetism</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1157 PATO:0001682 magnetism magnetic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A magnetic behavior exhibited 1) by materials which produce magnetic fields to exert attractive or repulsive forces on other materials or 2) by materials which become magnetized when exposed to a magnetic field.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>magnetic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_406 PATO:0001685 magnetic magnetic behavior 1-D extent 1-D extent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in an bearer by virtue of its extension in one dimension.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>1-D extent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1226 PATO:0001708 2-D extent 2-D extent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in an bearer by virtue of its extenstion in two dimensions.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>2-D extent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1233 PATO:0001709 3-D extent 3-D extent <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in an bearer by virtue of its extenstion in three dimensions.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>3-D extent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1237 PATO:0001710 perimeter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 2-D extent quality which is equal to the distance around a given two-dimensional object.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>perimeter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1236 PATO:0001711 perimeter radiation quality <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in an object by virtue of how that object interacts with radiation.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>radiation quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1381 PATO:0001739 radiation quality acidity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in an entity by virtue of it containing acid (hydrogen ions).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>acidity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1197 PATO:0001842 acidity hydrophobic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable property which inheres in a molecule that lacks affinity for water molecules, or has a tendency to repel or not to mix with water molecules.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrophobic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_399 PATO:0001885 hydrophobic hydrophobicity hydrophilic <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable property which inheres in a molecule that has a strong affinity to a water molecule, or has a tendency to mix with or wetted by water molecules.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hydrophilic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_204 PATO:0001887 hydrophilic hydrophilicity movement quality <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a bearer by virtue of its participation in movement.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>movement quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1313 PATO:0001906 movement quality chemical reaction <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process involving the interconversion of chemical species.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chemical reaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1596 REX:0000002 chemical reaction photoluminescence <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Luminescence arising from photoexcitation.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>photoluminescence</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1400 REX:0000038 photoluminescence fluorescence <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Photoluminescence which occurs essentially only during the irradiation of a substance by electromagnetic radiation.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fluorescence</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1401 REX:0000043 fluorescence phosphorescence <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A photoluminescence which is long-lived compared to fluorescence, and involves change in spin multiplicity, typically from triplet to singlet or vice versa. The luminescence from a quartet state to a doublet state is also phosphorescence. [source: http://goldbook.iupac.org/P04569.htm]</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>phosphorescence</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1444 REX:0000044 phosphorescence inhibition <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The decrease in rate of reaction brought about by the addition of a substance (inhibitor), by virtue of its effect on the concentration of a reactant, catalyst or reaction intermediate.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>inhibition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1631 REX_0000218 inhibition luminescence <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Spontaneous emission of radiation from an electronically or vibrationally excited species not in thermal equilibrium with its environment.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>luminescence</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1399 REX:0000290 luminescence chemiluminescence <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Luminescence resulting from a chemical reaction.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>chemiluminescence</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1402 REX:0000294 chemiluminescence emission <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Radioactive deactivation of an excited state of a material entity by which energy is transferred from the material entity to an electromagnetic field.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>emission</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1398 REX:0000303 emission unit of measurement <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quantitative measure of a property, which is a quantity chosen as a standard measure in terms of which other quantities (measured numerical values) are expressed in.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>unit of measurement</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1153 UO:0000000 unit unit of measurement length unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the distance between two points.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>length unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1241 UO:0000001 length unit unit of length mass unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of measurement which is a standard measure of the amount of matter/energy of a physical object.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mass unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1172 UO:0000002 mass unit unit of mass time unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A base unit which is a standard measure of the dimension in which events occur in sequence.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>time unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1275 UO:0000003 time unit unit of time temperature unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the average kinetic energy of the particles in a sample of matter.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>temperature unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1288 UO:0000005 temperature unit unit of temperature substance unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A base unit which is a standardized quantity of an element or compound with uniform composition.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>substance unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1216 UO:0000006 substance unit unit of amount of substance meter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A length unit which is equal to the length of the path traveled by light in vacuum during a time interval of 1/299 792 458 of a second.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>meter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1242 UO:0000008 m meter kilogram <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to the mass of the International Prototype Kilogram kept by the BIPM at Svres, France.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>kilogram</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1179 UO:0000009 kg kilogram second <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to the duration of 9 192 631 770 periods of the radiation corresponding to the transition between the two hyperfine levels of the ground state of the caesium 133 atom.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>second</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1276 UO:0000010 s second Kelvin <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thermodynamic temperature unit which is equal to the fraction 1/273.16 of the thermodynamic temperature of the triple point of water.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Kelvin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> K Kelvin NPO_1291 UO:0000012 mole <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance unit which is equal to the amount of substance of a molecular system which contains as many elementary entities as there are atoms in 0.012 kilogram of carbon 12.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1221 UO:0000013 mol mole centimeter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A length unit which is equal to one hundredth of a meter or 10^[-2] m.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>centimeter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1243 UO:0000015 centimeter cm millimeter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A length unit which is equal to one thousandth of a meter or 10^[-3] m.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>millimeter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1244 UO:0000016 millimeter mm micrometer <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A length unit which is equal to one millionth of a meter or 10^[-6] m.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>micrometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1245 UO:0000017 micrometer µm nanometer <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A length unit which is equal to one thousandth of one millionth of a meter or 10^[-9] m.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1246 UO:0000018 nanometer nm angstrom <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A length unit which is equal to 10 [-10] m.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>angstrom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> A NPO_1247 UO:0000019 angstrom gram <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to one thousandth of a kilogram or 10^[-3] kg.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gram</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1180 UO:0000021 g gram milligram <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to one thousandth of a gram or 10^[-3] g.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>milligram</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1181 UO:0000022 mg milligram microgram <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to one millionth of a gram or 10^[-6] g.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>microgram</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1182 UO:0000023 microgram µg nanogram <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to one thousandth of one millionth of a gram or 10^[-9] g.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanogram</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1183 UO:0000024 nanogram ng degree celsius <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A temperature unit on the Celsius scale based on which the freezing point of water is 0 degrees Celsius and the boiling point is 100 degree Celsius at standard conditions. Celsius scale has its zero at 273.15 K.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>degree celsius</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1289 UO:0000027 deg. C degree celsius millisecond <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to one thousandth of a second or 10^[-3] s.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>millisecond</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1277 UO:0000028 millisecond ms microsecond <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to one millionth of a second or 10^[-6] s.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>microsecond</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1278 UO:0000029 microsecond µs minute <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time derived unit which is equal to 60 seconds.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>minute</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1281 UO:0000031 min minute hour <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to 3600 seconds or 60 minutes.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hour</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1282 UO:0000032 h hour day <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to 24 hours.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>day</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1283 UO:0000033 day week <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to 7 days.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>week</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1284 UO:0000034 week wk month <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is approximately equal to the length of time of one of cycle of the moon's phases which is taken to be equal to 30 days.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>month</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1178 UO:0000035 month year <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to 12 months.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>year</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1177 UO:0000036 y year micromole <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance unit equal to a millionth of a mol or 10^[-6] mol.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>micromole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1223 UO:0000039 micromole µmol millimole <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance unit equal to a thousandth of a mol or 10^[-3] mol.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>millimole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1222 UO:0000040 millimole mmol nanomole <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance unit equal to one thousandth of one millionth of a mole or 10^[-9] mol.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanomole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1224 UO:0000041 nanomole nmol area unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the amount of a 2-dimensional surface.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>area unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1248 UO:0000047 area unit unit of area concentration unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which represents a standard measurement of how much of a given substance there is mixed with another substance.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>concentration unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1168 UO:0000051 concentration unit unit of concentration mass density unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A density unit which is a standard measure of the mass of a substance in a given volume.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>mass density unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1264 UO:0000052 mass density unit unit of mass density molar mass unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the mass of a homogeneous substance containing 6.02 x 1023 atoms or molecules.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molar mass unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1184 UO:0000055 molar mass unit unit of molar mass molar volume unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the volume of a homogeneous substance containing 6.02 x 1023 atoms or molecules.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molar volume unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1260 UO:0000056 molar volume unit unit of molar volume unit of velocity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A standard measure of the rate of movement. Speed is measured in the same physical units of measurement as velocity, but does not contain the element of direction that velocity has. Speed is thus the magnitude component of velocity.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>unit of velocity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1328 UO:0000060 unit of speed unit of velocity unit of molarity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A concentration unit which is a standard measure of the number of moles of a given substance per liter of solution.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>unit of molarity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1187 UO:0000061 unit of molarity molar <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of concentration which expresses a concentration of 1 mole of solute per liter of solution (mol/L).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molar</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> M NPO_1207 UO:0000062 molar millimolar <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of molarity which is equal to one thousandth of a molar or 10^[-3] M.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>millimolar</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1208 UO:0000063 mM millimolar micromolar <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of molarity which is equal to one millionth of a molar or 10^[-6] M.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>micromolar</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1209 UO:0000064 micromolar µM nanomolar <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of molarity which is equal to one thousandth of one millionth of a molar or 10^[-9] M.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanomolar</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1210 UO:0000065 nM nanomolar unit of molality <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A concentration unit which is a standard measure of the number of moles of a given solute per kilogram of solvent.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>unit of molality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1188 UO:0000067 unit of molality molal <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of concentration which expresses a concentration of a solution of 1 mole per kilogram of solvent (mol/kg).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>molal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1211 UO:0000068 mol/kg molal millimolal <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molality unit which is equal to one thousandth of a molal or 10^[-3] m.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>millimolal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1212 UO:0000069 millimolal mmol/kg micromolal <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molality unit which is equal to one millionth of a molal or 10^[-6] m.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>micromolal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1213 UO:0000070 micromolal µmol/kg nanomolal <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molality unit which is equal to one thousandth of one millionth of a molal or 10^[-9] m.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanomolal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1214 UO:0000071 nanomolal nmol/kg unit of normality <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A concentration unit which is a standard measure of the number gram equivalents of solute per liter of solution.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>unit of normality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1189 UO:0000074 unit of normality normal <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of concentration which is one gram equivalent of a solute per liter of solution. A gram equivalent weight or equivalent is a measure of the reactive capacity of a given molecule.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>normal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> N NPO_1215 UO:0000075 normal square meter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An area unit which is equal to an area enclosed by a square with sides each 1 meter long.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>square meter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1249 UO:0000080 m^[2] square meter square centimeter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An area unit which is equal to one thousand of square meter or 10^[-3] m^[2].</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>square centimeter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1250 UO:0000081 cm^[2] square centimeter square millimeter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An area unit which is equal to one millionth of a square meter or 10^[-6] m^[2].</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>square millimeter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1251 UO:0000082 mm^[2] square millimeter kilogram per cubic meter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in kilograms divided by the volume in cubic meters.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>kilogram per cubic meter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1269 UO:0000083 kg/m^[3] kilogram per cubic meter gram per cubic centimeter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in grams divided by the volume in cubic centimeters.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gram per cubic centimeter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1270 UO:0000084 g/cm^[3] gram per cubic centimeter grams per cubic centimeter kilogram per mole <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molar mass unit which is equal to one kilogram of mass of one mole of chemical element or chemical compound.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>kilogram per mole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1185 UO:0000087 kg/mol kilogram per mole gram per mole <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molar mass unit which is equal to one gram of mass of one mole of chemical element or chemical compound.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gram per mole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1186 UO:0000088 g/mol gram per mole cubic meter per mole <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molar volume unit which is equal to 1 cubic meter occupied by one mole of a substance in the form of a solid, liquid, or gas.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cubic meter per mole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1261 UO:0000089 cubic meter per mole m^[3]/mol cubic centimeter per mole <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molar volume unit which is equal to 1 cubic centimeter occupied by one mole of a substance in the form of a solid, liquid, or gas.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cubic centimeter per mole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1262 UO:0000090 cm^[3]/mol cubic centimeter per mole meter per second <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A speed/velocity unit which is equal to the speed of an object traveling 1 meter distance in one second.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>meter per second</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1329 UO:0000094 m/s meter per second volume unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the amount of space occupied by any substance, whether solid, liquid, or gas.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>volume unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1253 UO:0000095 unit of volume volume unit cubic meter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A volume unit which is equal to the volume of a cube with edges one meter in length. One cubic meter equals to 1000 liters.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cubic meter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1254 UO:0000096 cubic meter m^[3] cubic centimeter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A volume unit which is equal to one millionth of a cubic meter or 10^[-9] m^[3], or to 1 ml.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cubic centimeter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1255 UO:0000097 cc cm^[3] cubic centimeter milliliter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A volume unit which is equal to one thousandth of a liter or 10^[-3] L, or to 1 cubic centimeter.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>milliliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1256 UO:0000098 mL milliliter liter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A volume unit which is equal to one thousandth of a cubic meter or 10^[-3] m^[3], or to 1 decimeter.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>liter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> L NPO_1257 UO:0000099 liter microliter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A volume unit which is equal to one millionth of a liter or 10^[-6] L.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>microliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1258 UO:0000101 microliter µL nanoliter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A volume unit which is equal to one thousandth of one millionth of a liter or 10^[-9] L.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanoliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1259 UO:0000102 nL nanoliter frequency unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the number of repetitive actions in a particular time.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>frequency unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1331 UO:0000105 frequency unit hertz <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A frequency unit which is equal to 1 complete cycle of a recurring phenomenon in 1 second.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>hertz</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Hz NPO_1332 UO:0000106 hertz force unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of measurement for the force applied to accelerate a mass (an amount of matter).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>force unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1173 UO:0000107 force unit unit of force Newton <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A force unit which is equal to the force required to cause an acceleration of 1m/s2 of a mass of 1 Kg in the direction of the force.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Newton</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> N NPO_1174 Newton UO:0000108 nanosecond <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to one thousandth of one millionth of a second or 10^[-9] s.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>nanosecond</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1279 UO:0000150 nanosecond ns half life <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity which inheres in a chemical or element which represents the period over which the amount, activity or concentration of a specified chemical or element falls to half its original amount, activity or concentration. The realization is the observation of change in the concentration, activity or amount of the bearer.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>half life</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1280 UO:0000152 half life t1/2 percent mass per mass % w/w <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A percentage unit of concentration which denotes the mass of a substance in a mixture as a percentage of the mass of the entire mixture.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>percent mass per mass</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C48528 NPO_1324 UO:0000163 mass percentage percent mass per mass percent weight per weight percent weight/weight w/w % weight-weight percentage percent mass per volume % w/v <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A percentage unit concentration which denotes the mass of the substance in a mixture as a percentage of the volume of the entire mixture.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>percent mass per volume</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C48527 NPO_1326 UO:0000164 mass volume percentage percent mass per volume percent weight per volume weight-volume percentage percent volume per volume % v/v % vol <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A percentage unit concentration which denotes the volume of the solute in mL per 100 mL of the resulting solution.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>percent volume per volume</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NCIT:C48571 NPO_1325 UO:0000165 percent volume percent volume per volume percent volume/volume volume percentage parts per notation <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dimensionless concentration notation which describes the amount of one substance in another.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>parts per notation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1319 UO:0000166 parts per notation parts per thousand <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dimensionless concentration notation which denotes the amount of a given substance in a total amount of 1000 regardless of the units of measure as long as they are the same.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>parts per thousand</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1322 UO:0000168 parts per thousand ppth parts per million <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dimensionless concentration notation which denotes the amount of a given substance in a total amount of 1,000,000 regardless of the units of measure used as long as they are the same or 1 part in 10^[6].</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>parts per million</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1321 UO:0000169 parts per million ppm gram per milliliter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in grams divided by the volume in milliliter.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gram per milliliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1265 UO:0000173 g/mL gram per milliliter grams per milliliter kilogram per liter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in kilograms divided by the volume in liters.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>kilogram per liter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1272 UO:0000174 kg/L kilogram per liter kilograms per liter gram per liter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in grams divided by the volume in liters.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>gram per liter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1271 UO:0000175 g/L gram per liter grams per liter milligram per milliliter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in milligrams divided by the volume in milliliters.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>milligram per milliliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1266 UO:0000176 mg/mL milligram per milliliter milligrams per milliliter density unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the influence exerted by some mass.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>density unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1263 UO:0000182 density unit unit of density dimensionless unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of measurement of which is dimensionless.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dimensionless unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1154 UO:0000186 dimensionless unit percent % <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A ratio unit which denotes numbers as fractions of 100.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>percent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1323 UO:0000187 percent percentage count <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dimensionless unit which denotes a simple count of things.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>count</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1320 UO:0000189 count degree Fahrenheit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A temperature unit on the Fahrenheit scale in which the freezing point of water is 32 degrees Fahrenheit and the boiling point is 212 degrees at standard conditions, placing the boiling and freezing points of water 180 degrees apart. -40 degrees Fahrenheit is equal to -40 degrees Celsius.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>degree Fahrenheit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1290 UO:0000195 deg. F degree Fahrenheit pH <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>The logarithm of the reciprocal of hydrogen-ion concentration in gram atoms per liter. (source:Princeton WordNet)</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>WordNet</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1198 UO:0000196 pH unit of cell concentration <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A concentration unit which denotes the average cell number in a given volume.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>unit of cell concentration</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1194 UO:0000200 unit of cell concentration cells per milliliter <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of cell concentration which is equal to one cell in a volume of 1 milliliter.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>cells per milliliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1205 UO:0000201 cells per milliliter cells/mL electric potential difference unit <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A standard measure of the work done per unit charge as a charge is moved between two points in an electric field.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>electric potential difference unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1295 UO:0000217 electric potential difference unit unit of electric potential unit of electric potential difference volt <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric potential difference unit which is equal to the work per unit charge. One volt is the potential difference required to move one coulomb of charge between two points in a circuit while using one joule of energy.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>volt</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1296 UO:0000218 V volt coulomb <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electrical charge unit which is equal to the amount of charge transferred by a current of 1 ampere in 1 second.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>coulomb</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> C NPO_1294 UO:0000220 coulomb dalton <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to one twelfth of the mass of an unbound atom of the carbon-12 nuclide, at rest and in its ground state.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dalton</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Da NPO_1175 UO:0000221 dalton kilodalton <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to one thousand daltons.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>kilodalton</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1176 UO:0000222 kDa kilodalton weber <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of magnetic flux which is equal to the amount of flux that when linked with a single turn of wire for an interval of one second will induce an electromotive force of one volt.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>weber</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1160 UO:0000226 V s Wb volt-second weber Tesla <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of magnetic flux density which is equal to one weber per square meter.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>Tesla</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1165 T Tesla UO:0000228 Wb/m^[2] volt-hour <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of magnetic flux which is equal to 3600 Wb.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>volt-hour</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1161 UO:0000229 Vh volt-hour kilovolt-hour <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of magnetic flux which is equal to one thousand volt-hours.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>kilovolt-hour</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1162 UO:0000230 kV h kilovolt-hour millivolt <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric potential difference unit which is equal to one thousandth of a volt or 10^[-3] V.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>millivolt</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1297 UO:0000247 mV millivolt kilovolt <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric potential difference unit which is equal to 10^[3] V.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>kilovolt</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1298 UO:0000248 kV kilovolt microvolt <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric potential difference unit which is equal to one millionth of a volt or 10^[-6] V.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>microvolt</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1299 UO:0000249 microvolt µV decibel <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is an indicator of sound power per unit area.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>decibel</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1354 UO:0000259 dB decibel entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An entity is a thing which exists in reality.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_258 entity continuant <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An entity [bfo:Entity] that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>continuant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Examples: a heart, a person, the color of a tomato, the mass of a cloud, a symphony orchestra, the disposition of blood to coagulate, the lawn and atmosphere in front of our building NPO_259 continuant endurant snap:Continuant dependent_continuant <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that is either dependent on one or other independent continuant [snap:IndependentContinuant] bearers or inheres in or is borne by other entities.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>dependent continuant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> In order for a dependent continuant to exist, some other entity must exist. NPO_607 dependent continuant snap:DependentContinuant disposition <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity [snap:RealizableEntity] that essentially causes a specific process or transformation in the object [snap:Object] in which it inheres, under specific circumstances and in conjunction with the laws of nature. A general formula for dispositions is: X (object [snap:Object] has the disposition D to (transform, initiate a process) R under conditions C.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>disposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_155 Source:Robert Arp and Barry Smith "Function, Role and Disposition in Basic Formal Ontology" NATURE PROCEEDINGS, 2008. The process occurs as a result of the object's physical structure. A disposition invariably or definitely leads to a certain result given certain circumstances (if not, then the realizable entity is a tendency and not a disposition). disposition snap:Disposition function <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity [snap:RealizableEntity] the manifestation of which is an essentially end-directed activity of a continuant [snap:Continuant] entity in virtue of that continuant [snap:Continuant] entity being a specific kind of entity in the kind or kinds of contexts that it is made for.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> A realizable entity, which is a necessary function of the bearer, and it is realized as an end-directed activity (a process in which the bearer is a participant). NPO_316 [source]: (1) BFO.owl 1.1; (2) Robert Arp and Barry Smith "Function, Role and Disposition in Basic Formal Ontology" NATURE PROCEEDINGS, 2008. a function "f" is a realizable dependent continuant; it has a bearer which is an independent continuant; instances of Function F have realizations; each realization is a) a process in which the bearer is participant; b) that It occurs in virtue of the bearer's physical make-up or structure. c) and this physical make-up is something which the bearer possesses because of how it came into being. function snap:Function generically_dependent_continuant <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that is dependent on one or other independent continuant [snap:IndependentContinuant] bearers. For every instance of A requires some instance of (an independent continuant [snap:IndependentContinuant] type) B but which instance of B serves can change from time to time. Examples: a certain PDF file that exists in different and in several hard drives</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>generically dependent continuant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Examples: a certain PDF file that exists in different and in several hard drives NPO_1600 generically dependent continuant snap:GenericallyDependentContinuant independent_continuant <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that is a bearer of quality [snap:Quality] and realizable entity [snap:RealizableEntity] entities, in which other entities inhere and which itself cannot inhere in anything.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>independent continuant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_118 independent continuant snap:IndependentContinuant substantial entity one_dimensional_region <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatial region [snap:SpatialRegion] with one dimension.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>one_dimensional_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1665 one_dimensional_region snap:OneDimensionalRegion quality <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A specifically dependent continuant [snap:SpecificallyDependentContinuant] that is exhibited if it inheres in an entity or entities at all (a categorical property).</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Example: compound x is related to organic compound through the relation "presence of carbon"; here, the quality that inheres in compound x is organic) Examples: the color of a tomato, the ambient temperature of air, the circumference of a waist, the shape of a nose, the mass of a piece of gold, the weight of a chimpanzee NPO_445 quality snap:Quality realizable_entity <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A specifically dependent continuant [snap:SpecificallyDependentContinuant] that inheres in continuant [snap:Continuant] entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>realizable entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_237 Source: (1) BFO.owl v. 1.1; (2) Robert Arp and Barry Smith "Function, Role and Disposition in Basic Formal Ontology" NATURE PROCEEDINGS, 2008. realizable entities are defined by the fact that they can be realized (manifested, actualized, executed) in occurrents of corresponding sorts. realizable entity snap:RealizableEntity role <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity [snap:RealizableEntity] the manifestation of which brings about some result or end that is not essential to a continuant [snap:Continuant] in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant [snap:Continuant] in some kinds of natural, social or institutional contexts.</ncicp:def-definition></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> At the instance-level, a role y is filled by x which is an instance of an independent continuant( x which takes the role of y: x is the filler, y is the role). A role y has a context P (e.g. an occurrent in which x is a participant). Every role term has its own qualities and behavior, given the context. NPO_517 role role is a realizable_entity whose manifestation brings about some result or end that is not typical of its bearer in virtue of the latter's physical structure. Rather role is played by an instance of the corresponding kind of continuant entity because this entity is in some special natural, social or institutional set of circumstances. (Source: Robert Arp and Barry Smith "Function, Role and Disposition in Basic Formal Ontology" NATURE PROCEEDINGS, 2008.) snap:Role spatial_region <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that is neither bearer of quality [snap:Quality] entities nor inheres in any other entities.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spatial_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1664 snap:SpatialRegion spatial_region specifically_dependent_continuant <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>specifically dependent continuant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1601 Synonyms: property, trope, mode; Examples: the mass of a cloud, the smell of mozzarella, the liquidity of blood, the color of a tomato, the disposition of fish to decay, the role of being a doctor, the function of the heart in the body: to pump blood, to receive de-oxygenated and oxygenated blood, etc. snap:SpecificallyDependentContinuant specifically dependent continuant three_dimensional_region <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatial region [snap:SpatialRegion] with three dimensions.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>three_dimensional_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Examples: a cube-shaped part of space, a sphere-shaped part of space. NPO_1667 snap:ThreeDimensionalRegion three_dimensional_region two_dimensional_region <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatial region [snap:SpatialRegion] with two dimensions.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>two_dimensional_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1666 snap:TwoDimensionalRegion two_dimensional_region zero_dimensional_region <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatial region [snap:SpatialRegion] with no dimensions.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>zero_dimensional_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Example: A point. NPO_1668 snap:ZeroDimensionalRegion zero_dimensional_region connected_spatiotemporal_region <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatiotemporal region [span:SpatiotemporalRegion] that has temporal and spatial dimensions such that all points within the spatiotemporal region are mediately or immediately connected to all other points within the same spatiotemporal region [span:SpatiotemporalRegion].</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>connected_spatiotemporal_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1671 connected_spatiotemporal_region span:ConnectedSpatiotemporalRegion connected_temporal_region <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A temporal region [span:TemporalRegion] every point of which is mediately or immediately connected with every other point of which.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>connected_temporal_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Examples: the 1970s years, the time from the beginning to the end of a heart attack, the time taken by cellular meiosis. NPO_1676 connected_temporal_region span:ConnectedTemporalRegion fiat_process_part <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A processual entity [span:ProcessualEntity] that is part of a process but that does not have bona fide beginnings and endings corresponding to real discontinuities.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>fiat process part</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_417 [source]: BFO v. 1.1 fiat process part is it synonymous with "stage" which refers to temporally distinguised parts of an occurrent (eg., "infancy", "childhood", "adolescence", "adulthood" in the "life of a human being")? span:FiatProcessPart occurrent <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An entity [bfo:Entity] that has temporal parts and that happens, unfolds or develops through time. Sometimes also called perdurants.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>occurrent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Examples: the life of an organism, a surgical operation as processual context for a nosocomical infection, the spatiotemporal context occupied by a process of cellular meiosis, the most interesting part of Van Gogh's life, the spatiotemporal region occupied by the development of a cancer tumor NPO_923 occurrent perdurant span:Occurrent process <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A processual entity [span:ProcessualEntity] that is a maximally connected spatiotemporal whole and has bona fide beginnings and endings corresponding to real discontinuities.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_336 [definition source]: BFO process span:Process process_aggregate <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A processual entity [span:ProcessualEntity] that is a mereological sum of process [span:Process] entities and possesses non-connected boundaries.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>process aggregate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_397 [source]: BFO v. 1.1 process aggregate span:ProcessAggregate process_boundary <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A processual entity [span:ProcessualEntity] that is the fiat or bona fide instantaneous temporal process boundary.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>process boundary</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_137 [source]: BFO v. 1.1 process boundary span:ProcessBoundary processual_context <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An occurrent [span:Occurrent] consisting of a characteristic spatial shape inhering in some arrangement of other occurrent [span:Occurrent] entities. Processual context [span:ProcessualContext] entities are characteristically entities at or in which other occurrent [span:Occurrent] entities can be located or occur.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>processual_context</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Examples: The processual context for a given manipulation occurring as part of an experiment is made of processual entities which occur in parallel, are not necessarily all parts of the experiment themselves and may involve continuant [snap:Continuant] entities which are in the spatial vicinity of the participants in the experiment. An instance of a processual context [span:ProcessualContext] is a mixture of processual entity [span:ProcessualEntity] which stand as surrounding environments for other processual entity [span:ProcessualEntity] entities. The class processual context [span:ProcessualContext] is the analogous among occurrent [span:Occurrent] entities to the class site [snap:Site] among continuant [snap:Continuant] entities. NPO_1669 processual_context span:ProcessualContext processual_entity <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm><ncicp:term-name>processual entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_703 [source]: BFO v. 1.1 processual entity span:ProcessualEntity scattered_spatiotemporal_region <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatiotemporal region [span:Spatiotemporal Region] that has spatial and temporal dimensions and every spatial and temporal point of which is not connectedd with every other spatial and temporal point of which.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>scattered_spatiotemporal_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1672 scattered_spatiotemporal_region span:ScatteredSpatiotemporalRegion scattered_temporal_region <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A temporal region [span:TemporalRegion] every point of which is not mediately or immediately connected with every other point of which.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>scattered_temporal_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Examples: The time occupied by the indiviual games of the World Cup. NPO_1677 scattered_temporal_region span:ScatteredTemporalRegion spatiotemporal_instant <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A connected spatiotemporal region [span:ConnectedSpatiotemporalRegion] at a specific moment.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spatiotemporal_instant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1673 span:SpatiotemporalInstant spatiotemporal_instant spatiotemporal_interval <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A connected spatiotemporal region [span:ConnectedSpatiotemporalRegion] at a specific moment.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spatiotemporal_interval</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1674 span:SpatiotemporalInterval spatiotemporal_interval spatiotemporal_region <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An occurrent [span:Occurrent] at or in which processual entity [span:ProcessualEntity] entities can be located.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spatiotemporal_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> NPO_1670 span:SpatiotemporalRegion spatiotemporal_region temporal_instant <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A connected temporal region [span:ConnectedTemporalRegion] comprising a single moment of time.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>temporal_instant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Examples: right now, the moment at which a finger is detached in an industrial accident, the moment at which a child is born, the moment of death. NPO_1678 span:TemporalInstant temporal_instant temporal_interval <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A connected temporal region [span:ConnectedTemporalRegion] lasting for more than a single moment of time.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>temporal_interval</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Examples: any continuous temporal duration during which a process occurs. NPO_1679 span:TemporalInterval temporal_interval temporal_region <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An occurrent [span:Occurrent] that is part of time.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition> <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>temporal_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm> Examples: the time it takes to run a marathon, the duration of a surgical procedure, the moment of death. NPO_1675 span:TemporalRegion temporal_region