>clbS|locus_tag=ECOK1_RS11325|product="colibactin self-protection protein ClbS"|protein_id=WP_000290498.1
ATGGCTGTTCCATCATCAAAAGAAGAGTTAATTAAAGCTATTAATAGTAATTTTTCTTTATTAAATAAGAAGCTAGAATC
TATTACGCCCCAACTCGCCTTTGAACCTCTATTGGAAGGGCACGCGAAGGGGACTACGATTAGCGTAGCGAATCTGGTTT
CCTATCTGATTGGCTGGGGAGAGCTGGTGTTACACTGGCATGACCAAGAGGCAAAAGGAAAAACTATTATTTTTCCTGAG
GAAGGATTTAAATGGAATGAATTGGGGCGTTTAGCACAGAAATTCTACCGTGACTATGAGGATATTACAGAGTACGAAGT
TTTATTGGCACGGTTAAAGGAAAATAAGCAGCAACTCGTGGCTTTGATTGAACGATTCAGTAACGACGAGCTTTACGGTA
AACCTTGGTATAATAAATGGACCCGAGGTCGTATGATTCAATTTAATACCGCCTCGCCTTATAAAAATGCTTCGGGGAGG
TTAAATAAACTGCAGAAATGTCTTGCAGAATAG
>clbQ|locus_tag=ECOK1_RS11330|product="colibactin biosynthesis thioesterase ClbQ"|protein_id=WP_000065646.1
ATGAGTAATATCAGTTTGTATTGTTTGCCATATTCAGGTGGTTCTGCCGCCATGTATTATAAATGGCGTAGCGTGCTGTC
GGACAATATTACTTTGCGGCCTTTAGAACCTGCGGGGAGGGGAACTAGAATACGCCAGCCGCTGTGTCTTACGATGGTGG
ATGCCGTCGCTGACCTTTATCAACAATTTGTGAAACACTACACAGGTGGAGACTACGCCATTTTTGGGCATAGTCTCGGA
GGGATCATGGCCTTCGAACTGGTGCATTATATTCTCGATCATGGACATGACATGCCATGCGCGCTGTTTTTTTCCGGCTG
TCGCCCACCCGATCGGGCCTCTCATGAAGTAATACTGCATACCTTGCCCGATCAGGCGTTTATGGAAGAGATCGTCAAGC
TGGGCGGAACTCCGGTTGATGTCTTTCGTAATAAAGAGTTAATGACAATTTTCACCCCCATCATTAAAAACGATTATCGG
CTCTATGAGCAGTATGTATTTCAGGCCAAGGCGCGCACATTAACCTGTCCGATCGTGCTATTTCATGGCGATGCTGACAA
TCTGGTAATGCAGGATGAATTACTTGCATGGGAAAAATTCACCACACGAAAGACGCGGACTATTATATTTCCTGCTGCCG
ATCATTTTTTTGTCGATAAGCATTTTGAACAGGTGGTAGGTTATGTGAACCAGACGATTGAATCACTCGAAATAGTAGGG
TAG
>clbP|locus_tag=ECOK1_RS11335|product="precolibactin peptidase ClbP"|protein_id=WP_002430641.1
ATGACAATAATGGAACACGTTAGCATTAAAACATTATATCATCTCCTGTGCTGTATGCTGCTCTTTATTTCCGCTATGTG
CGCTTTGGCGCAAGAACATGAGCCTATCGGGGCGCAAGATGAGCGCCTGTCGACATTAATTCACCAACGGATGCAGGAGG
CCAAGGTCCCAGCCCTTTCCGTAAGTGTGACCATTAAGGGGGTACGTCAGCGATTTGTCTACGGTGTTGCCGATGTGGCT
AGTCAGAAAGCGAATACTCTAGACACAGTTTACGAGCTGGGATCGATGAGTAAGGCGTTTACCGGACTTGTGGTGCAAAT
ACTGATTCAGGAAGGCAGACTCCGGCAAGGGGATGATATCATTACCTATCTGCCGGAAATGCGCTTGAATTATCAGGGAA
AACCTGCTTCCCTGACCGTGGCTGATTTCCTTTATCATACATCAGGATTGCCTTTTTCAACACTGGCTCGGCTGGAAAAC
CCTATGCCTGGGAGCGCTGTGGCACAGCAACTGCGCAACGAGAATCTGCTGTTTGCGCCGGGTGCGAAGTTTAGCTATGC
CTCCGCCAATTATGATGTGTTGGGCGCGGTGATTGAAAATGTGACGGGAAAAACCTTTACAGAGGTCATTGCGGAACGAC
TCACGCAGCCGCTGGGCATGTCGGCGACTGTGGCAGTTAAGGGGGATGAGATTATTGTCAACAAGGCAAGCGGCTATAAA
CTGGGATTCGGCAAACCCGTTCTGTTTCATGCGCCTCTGGCCCGGAACCATGTTCCTGCCGCCTATATCCATAGCACTCT
GCCTGATATGGAAATATGGATAGACGCCTGGTTGCACAGAAAGGCTTTGCCGGCAACGCTGCGTGAGGCGATGAGTAACA
GTTGGCGTGGTAATAGTGATGTTCCGCTTGCCGCAGACAATCGTATCCTCTATGCCAGCGGTTGGTTTATCGACCAGAAT
CAAGGCCCTTACATCAGTCACGGTGGGCAGAATCCAAACTTTTCTTCTTGCATTGCGTTGCGACCGGATCAGCAGATTGG
CATTGTTGCGCTGGCAAATATGAATTCGAATCTGATACTACAGCTTTGCGCGGATATCGATAATTATCTGCGCATTGGCA
AATATGCTGACGGCGCTGGTGATGCAATTACAGCCACCGATACCCTTTTCGTCTACCTCACGTTGTTGCTGTGTTTTTGG
GGGGCGGTGGTTGTAGTGCGCGGTGCTTTCCGTGTTTATCGCGCAACGGCGCATGGCCCTGGAAAACAGCAGAGGTTACG
TTTACGCGTACGTGACTATATCATCGCCTTGGCGGTTCCTGGGCTCGTGGCCGCCATGCTCTATGTCGCACCGGGTATAC
TATCTCCAGGACTTGACTGGCGTTTTATCTTGGTATGGGGTCCATCGAGCGTGTTGGCGATACCGTTCGGAATTATCCTG
TTAGCTTTCGTTCTGACATTAAATCATCAAATTAAACGAATTCTATTACACAACAAGGAGTGGGACGATGAGTAA
>clbO|locus_tag=ECOK1_RS11340|product="colibactin polyketide synthase ClbO"|protein_id=WP_001029878.1
ATGGCAAAGGATGATTTTACCTGTGGCTCACTGGATATTGCCATTATTGGCATGAGCGGGCGTTTTTCCGGTGCGGAATC
GGTGCCCGAGTGGTGGGATAAGTTGCTGGCGGGTGAGGAGTTCACTCAACCGACATGCACAGAAGACGATAATGGGAACC
CTTGGATTAGGCTGCGCAATATAATCACCGCTCCCTATGACTTCGATGCTGCATTTTTCAATATTCCGCCTGGCGAAGCC
CTGTTGATGGATCCGCAACAACGAATATTTCTTGAATGCTGCTACAACGCTCTTGAGCATGCGGGCTATATTCCCACGCA
ACTTAAGCGAGTCGGCGTCTATGGGGCGACCTACGCCAATAACTATTTTATCGATCGCGTCTATCCATACCTGAAGATGA
GCGGCGATCACCATTATCTTCAGGCGCAGATTGGTAACGAAAAGGATTACTTGTGTGCTCAGGTTGCCTACAAGTTGGGG
TTTACCGGACCCGCTGTGAGTGTACAGACCGCCTGTTCCAGTTCGTTGGTGGCAGCATATTTAGCATGCGAGGGGTTATT
GACTTTTCAAGCCGATGTTGCGTTGGCAGGTGGGGTCACCTTGGGTTTTTTACAGGCGCACGGCTACAGTCCGCAAGGTG
ATAAGCTGGTATCGCAAGACGGACACTGCGCCCCGTTTAGCGCTGAGGCGACCGGCACGGTATACAGCAGCGGTGCGGGA
GTTGTGGTGCTAAAACGTCTTGAGGATGCACTACGCGACCAAGACAGAGTGTATGCGGTGATTAAAGGAGGTGCGGTAAA
TAACGACGGCGGGCGTCGGCTGGGGTTTGTCGCCCCCAGCGTAGAAGGACAGGTAGAAGCGATCAATACGGCGCTTGCCG
CCGCAGAAGTCGTACCGACTGATATCGCACTGATCGAAACGCACGGTACCGGTACCCCGTTGGGTGATGAGATTGAGCTT
GAAGCTCTGCACCGGGTTTTCGCACCGGCATGTGCGCCGCACAGCATTCAATTGGGTGCGGTAAAAGCCAACTTGGGTCA
CCTGGGAGTCGCTTCCGGTATCGTCAGCTTAATGAAAACCGCACTGACGCTATATACTGGTTTAGTTCCCCCGCAGATCA
ACCTAGTAAATAAACATAAAAAACTGTTGCAGCCAGCCTCGCCATTTTATCTCAGTGATGTAGTGACTTCTGTCCCACAA
ACGAAAAGGATCCATGCCACCGTTAGTTCGTTTGGGCTGGGAGGGACCAATGCTCATTTGGTTCTGCAAAACTGGTGCGA
GACGCCTGCGCAAGCGGTGCAAGAAAATGAGCGCCGCCTGTTTTTCTTCAGCGCCAAAACGCCATTAGCCCTTAGACAAC
AGTTGGATGCTCATTATCACGCTCTGGCGACCTATGCGGAAGCAGATAAAGATCGTATCGCCTATACTCTCGCGCAACGC
CGGGCACATTTCCCGTATCGCTGTGCGCTGGCGGCAGACAGTGTGGTAGCGTTGCGTGCAAGTTTGGCGAAACTGCGGGA
TGCTGACATGTCTTTTACCCCTATCAATATGGAAACTACCTTGGTGTTCCTATATCCGGACCGGGACGATAAGCTGGAGA
GTGCCCTGACGCATTTGCTGGCTTGTCAACCTAACTTGCGCCAGCGGCACCAGCGCCTGTCTCAGGATGTTGCACAAATC
TGCGAACCAGCCGATTGGACGCCAGCATTGCGTCAGTTTATCCAGCAGGTGAGTCTTAGTGAATGGCTGATCGAACAAAG
TATCTCGCCTGTGCAGCACATCGGTTACCTGACGGGGGCTGCAGCAGCGCAGTATGTTGCGCGCATCATCTCACTGGAAA
ACGCTGTTCAGCAGGTGATTGTGGCTGAAACGACACCGGAGCAGACGCTGGCCGGCAACAGTGAACTGAGCGAAATATTG
GCTAATCTGGCGGTGACGGAGGGAACGCTGATGCTGGAAATCGGTCGCGCGGGGACGTTTTCCATATTGTATCACCAGCA
TGCGCAGTGGGTTGGGCAAACAGTATTTTCCCCCATGCTGAATACGGATACGCCTGAGGACATCCTGCCGCTGTTGGGCA
CTCTTTGGCAACGAGGAGTGACTATTTGTTTACCGGAAATGCCAGCCGTGCAGACTATAGGCTTACCCGGTTATTCGTTT
GATCGCGTCCGGTATGAAATTCAGTCCAGTGATGCGAGAGAGAACGCTATGTTACCAGTGAGTTATTTGTCGGTCAGCGA
CTTTGTGGAGAAAACCTGGCGTTCATTGTTATGCATCGATCATTATGACGAACACGCGGTTATTTTCGAATACGGAGCGA
CCTCGATGCACGTTATCTCTTTCGTCGACAGCTGTAACCACATTTATAAAATCGGACTGACTGCCGCCGATATTTATGCC
AGACCCGCTATCCGTGAGCACAGTGAATTTATCTCCGAATGTGTTGATGGTATTTTATGA
>clbN|locus_tag=ECOK1_RS11345|product="colibactin non-ribosomal peptide synthetase ClbN"|protein_id=WP_001327259.1
ATGATGTCGGGCAATCCGTTGTCGTGGCCACAGGAACAGTGCCACATCATTGATCAACTGTATCCTTACAGTGCCGTAAA
CATCATTGGTGGTGTGGTCACCATTGAGGGAATTGTCGATCTGCCCCGACTACACGCGGCCATCCAGTCCGCCATTCGGC
AATTTGATGCGTTGCGTATGTGGTTTGTGATGGGAGAGGAGAGTGAAGTGGTCAGCCAAGTGCAGCCTTATCACTGGCGC
GATATCCGCCATTTGACTTTTTCCCCAGATTATGACAAGGAGAACCTACGCCCAGCGGCGATCGAAACATTTGTTGATGA
GTGGTTCCGGCAGCCCTTTACCCTGCTGGCGCACGATTTGTTCGAGTTTGTCACCTTTACGTGCGGTGAACAATACAGCG
GTTATTTATTTAAAGCCCATCACGGCATTGCTGATGGTTGGTCAATGGCGTTGTTGTCAAACCATGTCAAGCGAGCATAC
GAACAGCAGGACGTACCAGATGATGCGTCACCAGCCTATAGCGCATTTCTGGCGCAGCAGCAATCTTATCAGGCGTCAAC
GCGCTTTGCCGTTGATCGTGGCTGGTGGCGTGACTATATCGACGAATACCGCGACTGCTTTCCAGACAGTTCCCCCATCG
TTACTACTGAGGGCATCAGTTGTTCCACTTGGCTTGAGCCAGCCATGATTAACCGTCTCTACAGGTTGTGTAATCGTTAT
GGCTGTACGCTTAATACGCTGTTTATTGCACTCTTCGCTCTCTATCGCGCCAGAGTATGGGGGGAGGAAAAAGGCGTAAT
AGGCGTGCCGTTAGCCAATCGGCATACTCGCGAGGCGCGGCGTTGCTTTGGCATGTTTACTAATCAATTGCCGCTGGCCT
ATCGACTGGTGCGCACGGAACGATTCTGTGAACGGGTGGCCTTTTTCCAGCGCGAACTGAAACGCGGTTTTAAACACAGC
AAATATCCCATTACCTTATTCAACCAGGATTTGGCGGAACAGGGGGGAGGGAAGTTGCGGGCGTTCGATTATTGCGTTAA
TTATTATAACTTTACCTATGAACGCCACATTGCAGGTGCCGCGCAACGCGTGGAGAGTTACTACAGCGGCGAGCAGTCCT
ATAAGCTACAGATTGTTTTGCAAACTGTTAATAATCATAAAGAAAGCCTTAGGTTGAGTCTGGAGGCGCTGCGTAGCGCT
TTCACTCCGCACCAACTGACAGCGATGAAAAATGGGCTGTTGGATTTAGTCACTGCATTGGATCGGCAACCTGACGCTCG
TCTAGGCGATCTCGAAGTCTATCCTGCGCCGCACGTCGCATTGGCATGTGGCTCACTCAAACCCTCATTTACTTCCCGAT
TTGCAGCGCAAGTTGTGGAGCATGGTGATCGCACAGCACTAATTGATAATGAACAGTCTTTGACTTATCGGCAGTTGGAT
GACGCTGTTGAGCGGGTTGCGCGTTATCTGCGCCAACAGGGGATCGGACGCGGTCAAGTGGTTGGGATTATCGCTGAGCA
TAGCGCTCAAACGGTGATGGTTATTTATGGTATTTTGCGCTGCGGCGCGGCATTTCTGCCGCTAAATCCCGCGTTGCCAA
CGACCCGCCTTTACGCCATGTGTCGTAAAGCGCAGGTAGCGCATATCCTTTACGATCCGGCGATGCATGAATTGACGCAG
GCGCTGGCGTTTCCCGCGTCCAGCTTGCTCCAGGCCTTAGCCACTTCGGCGCTTGCTAGAGAACCTTGGCCAGCTATTGA
ACCGCAGGATCTGGCATATGTGCTGTTTACCTCCGGATCGACCGGCGAGCCTAAGGGCGTGCAAGTCTCTCATGGCAATC
TGGCTAACTATCTCCATTTCGCCGCCGAACGTTACTTTACAGCGCAGGACCGGGCTGCGCTCTACTCTTCGCTGTCCTTC
GATTTGACCATCACTACGCTGTTCGCCCCCTTATGTGTGGGCGCTAGCATCAGCGTTTGTCGGCACGCCGAGAGCGAAAC
ATTGCTGCGCATGGCCGTGGTTGATCAGCCCAACACAGTGATCAAACTGACGCCTGCACACCTGCGGTTGTTGTGTGCGG
CTGGCATAAGCAGTGAGCAGATTCGTACCTTGGTGGTTGGCGGGGAGGATTTCAAGCGGGATCTGGCGCGTAAGGCGGCT
GCTCTCTTTCCTCAGGCCGTGATCTATAACGAATATGGGCCGACAGAGGCCACCGTTGGTTGCATGATCTATCGCTACAC
CGGGCAAGAAACGCTGCCTTCATTGCCCATCGGTATGGCGATCGACGGTTGCCAGGTAGCAATTTGCTCCCCTTGGGGCT
GTCCGGTACCGGAAGGCGAAACTGGTGAATTGGTGATTTATGGCGCGTCAGTGACGCAGGGCTATATCGATGCGCCGCAA
CAAACGGCCGCCGCCTACCTTAAAGATACCAATGGGGTGATGATTGGCTATCGCAGCGGTGATATTGGCTACGCCATCGC
TCCTAATACGCTGGTTTATCAGGGACGTAAAGACGATCAGGTCAAAATTAATGGCTATCGTATTGAGCTGTGCGAAATCG
AACAAGCGTTGTTGAGCGCACCTCAGGTAGAAAGTGCGGCGGTGGCGGTGATTGATGATGTGCAGGGGCAGCACAGCGGG
TTGCTAGCCTGCGTGACACCGTCATCTGTTGATGTAGCTACCGTAATGCAACATCTGCGTCAGCAATTACCCACCTACAT
GCAACCCAAGCAGTGCTGTGCTATCGCCCAACTGCCGCTATCGCACAATGGCAAGGTGGACGTGCGTCAGATGGTCGCAA
CGGTCCGAAACACCGCGCCTGCATCGGGTAGCGAGCGGCTGGGAGATGCGGCGATAAGGCATTCAGTTCGGGTATGTGTG
GAAGGGGCGCTGGAGCAAACTGAGTTTGATGATAACGAAAATCTTTATGTCTTGGGGTTGGACTCCATCAAGAGTATCCA
GATTGCAGCGCAGCTCAGGCACCACGGCTGGACGATGTCAGCGGTGCAGGTGATGGAGTGTGGAACAGTGAACGCCATCT
GTGAGTTTCTCGCTAGTCATACAACGGTGTCACAGCTCGCGCAGTATGCTCATAACACCCGTATCGATCTACCCGCATTG
CGTTGGTTTACGCAGTTGGCGTTGCCAGTGCCCAATGTTTATAACCATGTCATTGTGCTGAAAGTGTTGCCGGGCTGCCC
GCTCGAGCAGTTACACAACAGGCTGCATACATTAATCCAGCAGCAGCCAGCTTTGCACAGTGCGCTGGACGCTGAGGGGC
GGTTGCTAGTATGCGACCCTAATGTGTGTTATCCCAACGAGGTGCTCACGGAATATTCGACGGCGCAGTGGACGTTGGCA
GAGGTGATCGCTCAGTGCAATAGCATGCTTGACGTGACAAATGGTCGAGTCTTTACGGCAGCTCTGTTACACGCCCCGCA
GCCTGCGTCTAGCACGCTGGTACTCTGTGCCCATCACTTGTGCGTCGATATGCACTCTTGGTATTTAATCCTCAGCACGC
TGGACGCCGTCAGCACTGTCAATGGCACCAGCAACAGCGGACTGCATCGCTGGAATGACTATCTGGCGAGCAAAACGGTA
GATTCCGCCACACACGAAAGCTGGCGCACAGTATGTCAAACGCTACCGCTGCATTTCCCACCCGTGTCATTGCCAGATGA
CTCATTACCTCGTACGCGCGCTTGGCGTGAAGACTTTCGCCATCCTTGCGTCAGGAGGTTGTTTGAATCCAGTGGTAATA
CCGCGTACAGCGCCGAAACCTATGTGCTAACGGCATTGGCGCTGGTGCTGCGTTACTACAGCGAAGAGCCTTGGTGTCGC
ATCGAGATGGAAGGCATGGGACGCGGCTGCTGGCCCGATGAGCCTGACGTTGCGGATACGGTCGGGTGGTTTACTCTATT
TTATCCTTGGGCGATCCCTCTGCATGGCGATATGGCGACACTGTTATCTGCGATCGCTTCCGATTTGGCAAAACGCACGC
ATGGTGGGGGAGATTACGGTCTGCTGCAAATGCGGCATGCACCGGAAGACTCTCTTGCGCAAGGGATCCGAATGAATTAC
ATCGGTGTGCAGGCGCAACCTTCACTCCGCTATTTTCATATTGATCACTTTAATAGTGATATCTATACCGCGCCTGAAAA
CGCGCTCGGCTGCGTGCTGGAGTTTAATATTGCGCGCTCGGCAGCTGATGGTCTCTCCTTCCACTGCCGTTTCGATCCCA
CGCGCATTGCGCTGAATGATGTGCAACTCCTGCTGGCGCGCTACAAGAACAGCCTCACTGATCTGGATGCCTGGCTGTGC
CAACACAGCGCCACGCTGACGGGCGCGCCGACTTTGTGGACACTATAA
>clbM|locus_tag=ECOK1_RS11350|product="precolibactin export MATE transporter ClbM"|protein_id=WP_000217768.1
ATGACGGTGAATAAGCTTGAGCCAGACAACGGCACGCCGAACGATGAGCTGTTCACGGTGGCGGGTATGTTTGACGGCTC
GCTGTATAAATTACTCCTGCGCATGGCGTTGCCGATGTTTGTCGGTATGTTAACGCAGGTGACCTATGCCATCGCCGATA
TTTTTTGGCTGAGCCACATTGATGTCACCAACAGCGGCATCATTGCCGGTGTGGGGCTGGTTTTCCCCGTTGGAATGGGG
TTATTTGCCATCGCCAACGGCATTCAAATCGGTATGGGATCTTTGCTGTCCCGCGCCATCGGCATGCAGCGGTTGGATCG
TGCACAGCGGATTTTGTCGGTCGGTATCATCATCGCGCTATTCTTTGCGATCGTGATCACCGTACTTGGCTATGTTTATG
CCCAGCCGCTATTGCGCTCACTGGGGGCCACGAAGAGCATCATCGGCTACGCAACGGAGTTCTATTATTATTCGCTGCTG
ACCGTGTTCAGCATCATGTTGATTGGCGTCATGATGGGGCTGTTTCAAGGCGCGGGTAAGATCATGGTCATCATGAAGGC
CTCATTGTTGGGGGCGTTGGTAAATATTATGCTCGATCCAATCATGATCTTTGTATTCGATTTTGGTGTGAAAGGGGTGG
CATTGGCGTCGTTTCTGGCGCAACTGAGTATGGTCGCCTATTTCATCTACACATTGATGGGATTACATATCGGGTTGAGT
ATACGCATCGCGTTACGCCCATTCTCCTGGAAAATCTACCGAGAGTTTCTCTCCGTCGGCATGGCGCAGATGCTGATGCA
ACTGATCATTGCGGTCGGCATAGTGATTTATAATTTTTTTATCGTCAGGCTGGACGTAAACGCGATGGCAGCGTTTACGC
TCACTGGTCGCATCGACTATTTCATCATCACGCCGATGCTGGCTATCGCGACCGCGTTGCTGACTGTGGTGGGGCAAAAC
TGGGGACACGGAAATGTCACCCGCACGCTGAATGCCTATTGGGCCGCCGTCGCGCTGGCCTTCTCTATTGTGCTGGTGTT
AGCCGTTATGCATATTGTACTGGCACCCTGGATGTATCCCCTGTTTACTCGTGTTGTTGCCGTGAGTGACTATGCGGTAC
TGCAAACCCGTATCATGGCACTGGCACTACCCTTTGTCGCTATCAGCCTGTTAGCAAGTGAATATTATCAGGCCATTGGT
AAGCCTTGGTATTCGGTGTTGTTGACGCTGATGCGTCACGTGTTTATATCTGTCCCTGTCGTATACCTGCTGGCGATTGT
GTTAGAGATGCGTATTACCGGCGTCTATTTTGGGGCGATGAGCGGCACTTTTGTGGCTGCGTTGTTGGCGTGGCGTCTGC
TGCGTCTTTCACCTCGTCTGCTGCGATGGAATCAGGAGGCGGTGCGCTCCCAACACTTGGATATGGAGGTGGCACCATGA
>clbL|locus_tag=ECOK1_RS11355|product="colibactin biosynthesis amidase ClbL"|protein_id=WP_001297937.1
ATGAGTGAGCAGAGCTATCGTAGCGCAGGGACACTGTTGGCACAGTTGGCGTCCGGAGAAACCACCTCAGTGGCGTTGGT
GAATCACTATTTTTCACGTATGGCGCAGTTTAACAAGCCGTTGAATGCGGTGGTGCAGCAGCACTATGCGTTGGCGTTGG
AGGCCGCCGCGCGCGCCGATCGTGAGCGACTGGAGGGGCGCGCAAGGGGCGTGTTGCACGGATTACCTTGTACTGTTAAG
GAGTCGTTTGACGTGCAAGGGTGGTTAACCACGTCCGGTGCCCATTATCTGAAAGATAACCGGGCGACGCAGGATGCTCC
TTCCATCGCACGCTTACGCGCTGCCGGGGCGATCCTGATGGGAAAAACCAATGTGCCGATGATGACTGCCGATTGGCAAA
CCTATAACGATCTGTATGGCACCACCCATAACCTGTGGGATAGGCAACGTTCACCCGGCGGATCGTCCGGAGGAGCGGCG
GTGGCGGTGGCGGCGGATTTCACCCCCGTGGAATTTGGCAGCGATTTGTTTGGCTCACTGCGCATTCCCGCACACTACAC
AGGTGTCTATGCCCATCGTTGTAGCTTGGGGTTGATGTCGGTCAGAGGACATGTGCCCGGTGGTGGTCCGCAAGCGACTG
ATGAGCCGGATCTCTCGACGGCGGGCCCCATGGCGCGCAGCGCGGCGGATCTGCGTCTGATGATGCGCGCATTGAGCACA
TTCTGGGTGGAACCGCCGCGTATTCCCGATTTTAGCCGTTATCAGGCCAAAGCAAACTACCGCGTGTGCACGTGGTTTAG
TGCGCCCCACCATGAGATAGATCAACAGATCGCACAGCGTTTTCAATCGTTTATCGACAAGTTACGCGCACAGCCTGGCG
TGGAGGTTGATGATGCTATGCCCGCCGATATCGATCCCGACGCACTGTTTGATATAGCAGTCAAACTCAGTGGTCGGCTG
GTAAGTACGGCGCTCAATGGACGCCAGCGTCTTACAGCCGGGCTGGCTGCGCTGGGCTTCAGGCTTGTGGGCAAGCTGGC
GGATGTGCCTGAGGGGATAACGAGCTATTACCAGGGCATGCTGAAAGACAGTGGCGAACAGCGGAATACAGACAAACTCC
GCCACGAATACAGCCGGGTGATAGAAACCCTTTTCGCGCGTTATGACGTGTTGTTGACACCTGTCAGCCCGGTGCTGGCG
TTTGCGCACATGCAGCAGCCGGTGCGTAAGCGCAAGCTTATCGTCAATGGCGAACCGCAAGATTACAACGAACATTTGTT
CTGGAACATGTTAGCAACGGTTTTTGGTTTGCCTGCCACCGTTTACCCATTGGCGAAAACGATGGATGAGCTTCCGTGCG
GCATACAGATCATTTCCGGGCATTTTCACGATGATGTGACGATTAACTTTGCTGAGTTCTGCGAAAGCATCAGTGGCGGA
TTCACGGTACCGGAAGGGTACTAG
>clbK|locus_tag=ECOK1_RS11360|product="colibactin hybrid non-ribosomal peptide synthetase/type I polyketide synthase ClbK"|protein_id=WP_000222467.1
ATGACTTACAGTGAAAGCGATATTGCCATTGTTGGCATGAACTGCCGGTACCCCGGCGTGCACAGCGTTGCGGCATTCGA
AACGGTGCTTCGCACCGGATGCAACATTTTGGACCCCAAAGTGACCCCGAGCAACGGCCACAATCACATTACGCTGAACA
ACGTCTATGAGCACATGGCGGAGTTCGATGCCAACTTTTTTGGCTACAGCCGTGCAGAAGCAGAAATCATGGATCCACAG
CAGCGCGTATTTCTGACCTGTGCTTGGGAGATGTTTGAACAAAGCGGTTACAACCCGAAGCAGCACGATGCGCGCGTCGG
CCTATATGCGGGCGTGAGTACCAGCTTCTATTTGCTTACTCACCTGATGAACAACCCAGACAAGCTTGCACAACTCGGTG
GTCTCCAAATCATGGTCGGCAATGACAAAGATCATTTGACGTCCCAACTGGCTTACCGCCTGAATATTACCGGCCCTTGC
GTGACGGTTCAGGCCAGTTGTGCCACCTCGCTGGTGGCAGTGCATCTGGCCTGCGAAGGGCTGCTGAGCGGTCAGTGCGA
TATGGCGCTAGCGGGTGGCGTCACGTTTCGCATGGAGGAGCAGCGCAGCTATGAATCGCACGGTGATGGGCTGCAAGCAG
AGGATGGCCTGATTCATACTTTTGATGCGCAGGCGAGCGGTACGGTCTACAGCAGTGGTTTGGGCATGGTGCTGCTCAAA
CGGGCTACAGACGCGCAGGTGCAAGGGGATAACATCCTTGCCGTCATCAAGGGAAGCGCCATCAACAATGATGGCGGTGC
GCGCAGTGGTTATACCGTGCCGGGTGTTGATGGTCAGGAAGCTGTGATGATTGAGGCGCATAGCTTGGCGGAGGTGACGC
CGCAGCAAATTCAGTATCTAGAACTGCATGGCAGCGGCACGCCGTTGGGTGACGCTATCGAATTCGCGGCCATCAAACGT
GTGTTTGGGACGCCAGCGCCGAATGCGACACCGTGGCGTCTGGGGGCTGTGAAACCTAACGTGGGTCACGTAGAAATGGC
ATCTGGCATCACCAGTCTCATAAAAACGGTGCTGAGTCTTACTAACCGGGTGTTTTACCCTACGCTGAATTTTCAACGGG
CTAATCCGCAACTGGGGTTGGAGGACAGCCCGTTTGAAGTGGTGTCCCGTTTAACGCCTTGGCCGGAGGGCACCACGCCA
CGCACCGCTGGTGTGAGTGCGTTCGGATTGGGCGGCACCAACGCACATCTGGTGGTACAAGCGCCGTTATCGACGCCGCA
GGCGAGGGCGCAGCAGATGGGGCCTTGTGTCGTTGTACTCTCGGCAAAAAACCACAATGCCCTGGAACAGATGCAAAACG
CCCTGCTGGCGAAACTGGCCGCACATCCAGAGATACGCTTACAGGACGTGGCTTACACCCTGCGTCACGGGCGTTTCTCC
GCCCCGGTACGTAAGTGTGTCATCGCAGAGAATTGCACCCAGCTAGCCCGACAACTCCGCGACGCACCGATGGTGGAGGC
AACCACGGGTTGCACGATCTACTGGAGATTGGGGCACCGTTTCGTTGTTGCACTCGAGACGCTTAGTGACTGGCTGGCGT
GCTCTGAGGTGTTGTCACAGGCGGTGGGACAACTGCTCGAGCATTTTCCGCTCGAACCAGCCTGTCTGCAAGATCTCTCC
CCTGCGCAACGGACGTTTATCAGCCAGTATGCGCTGATCGCGTTGATTGACGAACGGGAAACGTTGAATGTGGTGCTATG
CGGCGACGGTGATGGTGGCTATGCTGCCGCCGTACTACGAGGAGACTGCACACTAGAGCAAGCATGGCACAGGTTGAATG
CGGGCCAACCGTTTGATGATGTGCCGACGAATCCCCTCTTGCAGCCCGATGTCTGCTCTTTGATGCTGGACGACGCGGCG
AGTGATGCCAATCGCACCGCGCTAGAGGCGTTAGGGCAGTTATGGTTGGCTGGCGTCAGCCTAGATTGGCGCTGGGTGGA
TGCGGCGGAGCGTATGTTGGGCAGTCAACGCATCGCCCTGCCGGGGACCGTTTTTACACCGCAGCGCTATTGGGTCGAGG
CCGTACGGCCTGCCACGTTCTCCCACGAATCGTCGAATAATCTCTTATCCCGCGCAACAAAATCCGATATTATTGCAGTG
GTGACGGAGATATGGGAACGCACGCTTGGTGTCAGCATTGATGATCACCACGCCAGCTTCTTCGAACTGGGTGGGCATTC
GCTGTTAGCGTCAACCATTTTATATGATATTCAGCAACGTTACGGCATCACCTGTACGCTAAGCGCATTCTTTGCCGATC
CCACCATCGAGGGATTAAGTTGCTATCTGCTCGAACAAGGCGGCAGTGAGACAGCGGTTTCAGCATTGCCTGATACGGTC
TTTGCCCCTGACCAGCAGCACCTACCTTTTCCGCTGACTGACGTGCAACAGGCCTATTGGGTTGGGCGGCGAAAATCCTT
GGGATTGGGCAATATTTCCACCCATATCTATGTGGAATATGAACTACAGGGGCTAGATGAAACAGCGTTCAACCGCGCGC
TCAATGCGGTGATTGCGCGGCACAGCATGTTGCGTGCAATTGTCAACGATGACGGTATGCAGCAGATATTGCCAAACGTG
CCGGAATACCACGTTGCCTTCTATACCACCCAGTGCGAGGATGCGTTTCAACAGCGTTGCCGTGAGCTGCGTGACACCCT
CTCACATCAGATGATTGATTGTAGTCGCTGGCCTCTGTTTCAGATGGAGGTCGTGGTTGATCCGCAGCAAAAAGCCCGGC
TACATGTATCTATCGACCTGCTGATAGCCGATGCATGGAGTCTGGAGTTGTTCATTCGGGAACTAGCTTATCACTACCGC
CATCCGCAGGCGGCATTGCCTACATTGACGTACAGTTTCCGCGACTATGTGCTGACCTTAAAATCCTACGAGAAAACGCC
GCAGTTTGAACGGGCACGTGACTACTGGCGCGCCCGCATCGAAACTCTGCCGCCGGGGCCACGATTGCCGCTGCGTACCG
ACCCCACGAAGCTGGAAAACCCCACATTCGTGCGCCGTAGCTATTGTCTATCTCGTGCTATCTGGCAGCGCTTGAAAACG
CAGGCGGGTCAGATGAGTATCACGCCTACTACACTGCTGCTCACGGGGTTTGCTCAGGTGTTGGCGCGCTTTAGTTCCTC
GCCGCACTTTAGCCTTAACCTGACGCTGTTTAATCGTCTGCCGTTGCACGCAGATATCAATCACTTAATTGGCGATTTTA
CTGCACTGACGTTGCTGGAGATTGATATGTCGCAGGGAGAAACCTTGCAGGCGCGGGCAAACGTGATCCACTCTCAACTG
TGGCGCGATTTGGATAACCGCTTGTTTGGCGGTATCCAGGTCTCTCGACTGCTGGTACAAACTCACCGCGATCCGGCGAA
ATCGGTGATTCCTATCGTGTTCACCAGCTTGCTCAATCAATATGAGGCGAGCTGGGAAACGGATGATACGCTGTTCAACC
AACCGCAGGATGATCTGTACAGTATTTCACAGACACCGCAGGTGTGGCTCGATCATCAGGTAATGGAGCGTAACGGGGAA
TTGCACTTTAATTGGGACGTGGTGGAACAATTGTTTGAACCGGCGCTAATGGATCAGATGTTCCAGTGTTATTGCCAACT
CCTGCACGCCCTAGCCCAGCGACCACAGCTCTGGCATGAGACTCAAGATGTGCTGGCGCTGCCCACCGTTAGTGCACCGG
TCACGCAGGCTCCTGCACCTACGGCCTTGTTGCACCATGGGTTACTGCGTCAGGCAGCACTGACGCCACAGGAAACTGCG
CTGATCAGTCCTATCCGTGAATTGACCTATCGCCAACTGTCGACGGCGGCGGATCATGTGGCCCGCGCCCTGTTAGCGCT
GGGCGTGCAGCATGGCGACCGCGTGGCGGTGGTGATGGAAAAAGGCTGGCAGCAGATTGCCGCCGTACACGGCATTTTAC
GACTGGGTGCGGTCTATCTGCCAGTGGATCCGGTGCTACCGCCACAGCGTCGCCAGCTTTTGCTGACGGTGGGCGAGGTG
CGGGTACAAGTAACGCAGCCGGGTCTCACGCAATTGGAGCCGTCGCTGCCCGTGCTGATCATCGACGACGGAATGCTGGA
CACGCCTGCTGCGCCGTTGCCTGAAGTGGCTGGGGATGTCACGGATCTGGCCTATATCATTTTCACTTCCGGCTCCACCG
GTACCCCGAAAGGAGTGATGATCGACCACCGTGCGGCCATGAACACACTGGAAGACATCAACGAACGCTTTGGCCTCAAT
GCGCAGGATAGGGTGTTCGGGCTGTCATCATTGAGCTTTGACCTGTCGGTTTACGATGCCTTTGCGCCTTTTATGGTGGG
TGCAGCGCTGGTACTGCCGGAAGCAGGACGGGAAAAAGATCCGCGTCATTGGCAGACAGTTATGGCACACGGTCATGTAA
GCGTCTGGAATGCAGTGCCCGCACTGATGCAGATGCTGTGCGAATACCACAGCGGCGATCGGATGAGTTATCCGACGTTG
CGTCTGGCACTGTTGAGCGGCGACTGGATCCCGCTAACGTTACCGGAGCAGATGCGCGAGCGGCTCAATGAAACGATGGA
CATCATCAGTCTGGGTGGAGCGACCGAGTGCGCCATCTGGTCGGTCTACTACCCGATAGGTGAGGTGGAATCGACGTGGA
CCAGTATTCCCTACGGTCGGGGCCTGCGCAACCAGCCAGTATACGTGCTAAATGCGCAACTGGAGGAATGTCCGGTCGGG
GTGGAAGGAGAGATTTGCATTGGCGGGATGGGGCTGGCACAAGGCTACCTGAACGACGCAGAGAAAACGGCGGCGAGCTT
TGTCTGGCGCGAAGCGAGTGGTGAGCGAATTTACCGCACTGGGGATCGCGGGCGCTACTTTGCTGACGGGCAAGTCGCCT
TTTTGGGGCGCAACGATACCCAAGTGAAGGTGAATGGTTACCGTATCGAACTGGGGGAAATCGAGCGCTGCATTGCGCGA
CATCCCGATGTGGAGCAGTCAGTGGTGGTGGCAGTGGGTAATTCTCAACATCGTCGGCTGGTCGCTTTTGCCAAACTGCA
CGATCGCCACCAGGCGCAGGCATTGCAAGCTAAGGAAGCGGAGGCGGCGGCACTGGCGCAGGGTATTATTGTGAATCCGG
CACAGCGTCTAGCGTTCAAACTCAAGGAGCCACATATTCGCGCGCTGGATGGTCTGGGCATTGCACTGACGGCACCGGCG
GATAGCACACGTTACATCAAACGCCGCAGCTATCGTCATTTCAGCGCGCAAAAAACCACGCTGGCACAGTTGGGGCAATT
GCTGTCGGGCTTGGGGCAGATGCGTCTACCCGGTCTACCTTTTGCCAAGTATGCCTATGCGTCCGCCGGGGGGCTATACC
CGGTGCAAACCTACGTGTACCTGCATCCAGACAAGATCGAAGAGGGAGTATCCGGTATTTACTACTTCGACCCGCGACAG
AGCTGTCTTATGCCGGTAGCACCAGAAGTCGAGCTGAACAGTGGTTTTCATGCCGGACCTAATCAGTCTATTGCCGATCG
GGCGGCATTCACGCTGTTTATGGTGGCTGATATGGCGGTGATCTCGCCATTCTATGGGCAAGAGGCAGCTTGGCACTTCT
CGGTGATGGAAGCAGGTACTCTCTGCCATTTACTGGAAGAAGATGCGCCGCGCTACGGATTGGGGCTGTGCCAACTTGGG
ATGGCAGACTTTTCCGCTGTGGCATCGCATTTTCAATTGTCGCCACATCATCGCTATGTCCATTGCACCGTGGGGGGCGC
GATAGGGCAAGAGGCGGCAAGTGCTGCAGCATTGCTGCGCGATTTCTCCACCTATGAGAAACCGAAGGAAACCGCTGCGC
CGCTGGACATGCAGAGCTACAAAGATGCCATGCTGCGCGGCCTGCGTCAGCAACTGCCTGACTATATGGTGCCGAGTGAT
CTGATGTTAGCGACCGATTTTCCGTTAACCGCTAACGGCAAGCTAGATCGGCAAAAATTACAGCTGCAGGGCGAACAAAT
TGCCCACCAGCGTGACGGCGTGGGTCCAATCCAGGTGGACAGTGCGTTACAACAGCGGCTGGTGGCGCTCTGGCAGGAGG
TACTCGGCGTGAGCCACGTGTCGGCCGAAGACGATTTCTTCTCGCTGGGGGGCAGTTCTATAGAATTGGTGCGTATTCAG
CAGGCACTTGAGGCGATTATCGGGCAGGAGATTCCCATTGTCGATCTGTTCCGTCTGCCAACCATCGCGGATGTGGCGCG
TTACCTTGATGAGCAACTGCACAATCTACCCGCCGCCCACGATATCGTATTAGCGCAGGCTGAGGTTTCGCAGGTCAGCG
CTGCGCGCGAGAATCTGGCGTTGCGGCGTAAACGTGCCCAACAGGGAGAAAAGGGCGATGAGTGA
>clbJ|locus_tag=ECOK1_RS11365|product="colibactin non-ribosomal peptide synthetase ClbJ"|protein_id=WP_001468003.1
ATGACGATACATCATGCCGCATTGGCGCGAATGTTACCGGCGGAAAAAAAGGAAAAGCTATTACGACAGTTGGCGCAATC
AGGCGTGTCGCCCAGCCGCATTCCCATCATCAAAGCGGATCCGGCGCAGGCAATCCCGCTGTCGTTTAATCAGGAGCGGT
TGTGGTTTTTGCAAAAATACGACAGTACCGCCACTAACTACAACCTTTATGTGGTGTATCGTTTGCATGGCGTGGTGGAT
ATGCCGATGCTCACGGAGGCATTGCGCCATGTGCAAGCACGCCACGCCATCTTGCGTACCCGTATCATAGTACGTAACGA
TCGGCCTTGCCAGGTGATAGATGATGCGTCTTCGTTAGTTCTCGATACGGTCACGCTGGCAGCGCAGGCCCCAACTTCAG
CGCTAGATGCGGTAATTCAGCAGGTGATAAACACCCGGTTCGATCTGGCACGCGGTCCTCTGTGGGGGGTAACTCAGATT
ATTCAACCCGATCAAGGTTGTCATTTGGTGTTTTGCGCGCACCATATCATCATCGACGGTATCTCGTTACGGCTATTGTT
CGATGAGTTACAGCAGCAGTATGCTCGATTGCATGCTGGTAATGAAACGTCGCTGCCTCCGCCGCCGCTGCAATATGCCG
ATTATGCCTTCTGGCAGCGCGAATGGTTCCAGGATACCTTGCTGGCGAACGAACTTGCCTACTGGCGTGCGCGTTTGCAA
GACGCGCCTCTGCTGTCGACATTTCCATCGCTGCACCCGCGCCCGGCACAACCCTCTACACATGGTTCCCGGTTCAGCAT
CACCCTGGATGAAACATTAAGCCTCGCGTTGAAACACGTAGCCCGCACGCAGGAAACAACGCCGTTCGTGCTGATGCTGA
CTGCCTTCCAACTGGTGCTGATGCGTTACGCTCAGCAACAGCGATTGGTGATAGGCATGCCAGTATCGGGGCGCATTCGC
CCGGAATTGCAGAGTAGCATTGGTTATTATGCCAGCACTGCGGTTATCTACACCGATTTTAATGGGGTTGAGGTAGGGCG
CGAGGCGCTCCAGCGTGTGAAGGCCAGCGTGAAAGAGACGCAGGGGCGCCAGCAACTGCCGTTTGAAAACTTGGTGAATA
TGCTGGATCTCCCTCGCAGCCTTTCCCATTCACCGTTGTTCCAGATCCTCTATATCTACCATAACCACGTGACCCCACGC
GCTTTTACCTTGGCTGGTGCGTATTGGGAGCAGGTGACGTATCACAATCAGACCGTCAAATACGACATGACAGTCGAGGT
GTTCCAAAACGACGCCACGTTCGACGTCTCCTTTGAGTACGATTTGGGGTTATACGATGCTGATGTGGTGAAGCAGATTG
CCGAGGCGCTGCGTCAGCACTGCTTATCGTTGACATCATCACTGGAGACCCCGATAGGGGCGATCCCTCTGCATGCACCG
GAGACCGCAACGCCGCGGCGTGATCCGCTCAACGCCACTAACGTCCCGTGGCTCGGGCCGCAGGATGTGCTGCGTATCAT
TGAACAGCGCTGTGTGCAGCACCCAAAGCAACTGGCAATACAGCAGCATGACGGCACACTGACCTACGCTGAGCTCTGGG
CGCGTGTGCAGTTCATCGCGATGCGTTTTCGAGCGCATGGCATACAACCGGGCGATCGTATTGGCGTGCTGTTGCCACGT
CACAGGGATGTGATTGCAACCATGTTGGCGACGTGGTTTGTGGGGGCGTGCTACGTGCCGTTCGATATTCATCAGCCTGC
CGCGCGTTTGCAACGCCTTATGCAACGCGCGCGTTTGGTCTGTCTGGTGGTCCGTCAGCCGGGAGAGTGGGGTGAAATTG
TACAACTGTCGTTGCCGGAATTGATGCAGGACATGTCGAATGCGATCCGGTATTCTACACCTTGCGCGCTGTTGCCGGAT
ATGCAGGCCTACCTGTTGTTTACCTCCGGCAGTACCGGTGAACCTAAAGGCGTGTGCGTTGTTCACCGCGGGTTGCTGAA
CTTGTTGTTGGATATGCAGCGTACCTTTGCGGTTGGCTCGCAAGACCGGCTGCTCTCGGTGACGACGCCAACATTTGATA
TCTCATTCTTGGAGTATCTGTTGCCGCTGATCTCCGGTGCGAGTCTCTATCTGACAGAGGCGGAACGCGCCGCAGACAGC
TTCCGTATGATTCCGCTGATTGCCGACTATCGACCAACGCTGATGCAGGCGACGCCCTCGTTCTGGCACGGGCTGTTGAT
GGCGGGTTGGCGTGGCGACCCGGAACTATGTGTGCTGGCAGGCGGTGAAGCGCTGCCAACGAAAGTGGCGGAAGAACTGT
TGCGCTGTTGTGGTTCATTGTGGAACCTCTACGGTCCCACCGAAACAACCATTTGGTCGCTGAAATCGCAGATAACCCAA
GCGGAAAACATCACCCTCGGCGCTCCCATTGCCAATACCCGTATATACATTCTGGACAATGAGGGCCATCCAGTGCCGCA
AGGCGTTGACGGCGAGCTTTACATCGCCGGGGATGGTGTGGCGCAAGGGTATGATGGGCAGCCTGAGTTGAACGCACAGT
TCTTCTTGTCAGAACCAGGGGTCCCCGGTGGCAGGATGTTCCGCACTGGCGATCTGGTCAGGAGTGATGCGCAGGGGCAG
TTGTTTTTTGTTGGGCGCAAAGATAGCCAGATCAAACTGCGCGGTTATCGTATTGAGTTAGGCGAAATTGAACGGACGTT
GGCACGGCATCCGCATGTGGACGCCGCGGTGGTGGCCTGTATTGAAAGAGCACCGTTACACAAAGCACTGGCAGCATTCA
TCATCACCAGTGAGCCTCCCTCGCTATTCGAGCAACTGAAAAACGAGCTTCGGCAGCAACTGCCAGACTATATGGTGCCA
ACGCTGTGGCAGAGGGTGGCCGACTTCCCGAACACTGACAACGGTAAAATCGATCGTAAGCGGTTAGCGGAAAATTTCGT
TGCCGATAGCTCCCTTGTGTCGCCGCAGACGCAAGCGCTGAGCGACACGGAACAGATGTTGCTGGCGCTGTGGATGCGCT
ATTTGCCGATAAAAAACGTCGATCCTGAGTGCGATTTCTTTCGCTTGGGGGGACATTCGCTGTTGGCGGTAACGTTGGTA
GCAGAGATCAACCGCACTTTTCACTGCGCCTTGACCCTGAAGGACATTTTCCACTACTCCACACTACGGGCACTGAGTGC
GCGTATTGCACAGCAATCTATCACGGACGCTGCCGCGTCTCAGGATGACTGGGTGATAGTGCACGACCCTGAGCATCGTC
ATCAACCGTTCCCATTGACGGATGTTCAGCGCGCCTACTGGCTTGGACGACAGACGGGTGCTACCTCGATCGCGACCCAC
ATCTACCATGAATTTGACGTAGAACACTTTAATGTTACGCGTTTTACCCATGCGGTGAATGCGCTGATCGCTCGCCATGA
AATGCTACGTGCGCGGGTACTCCCCGACGGTACTCAGCAGATTCTGGCGCAAGTGCCGGCGTATCAGTTAGAGCAGCGCG
ATCTGAGTGCTTTGTCCCCTAACGCACGAAACGATGCCTTGATGGCGATCCGCGATCGGCTGTCGCATCATGTGCATCCC
GCAGATCGTTGGCCGCTGTTTGATTTCAGTTATTCGGCTTGCACGGCGCAACATGGCCGCTTGCATTTCAGTCTCGATCT
GCTGATTGCCGATGCTCTGAGTATGCGCACGCTACAGCAGGAGTTGATGATGCTGTACCGTGAGCCCCATGTGTCACTGC
CGTTGCTACCGTTCTCTTTTCGTGACTACGTGCAGGCGCTGTTGGTAGAGCAGGCGAGTGAAGCCTATGCACGCGATCAG
GCCTATTGGCAACGGGCGCTGCCGCAGCTGTATGGCCCACCAACGCTGCCCGTACAGGGCGATTTGGCGCAACTGTCTGC
GATCAGGTTCGTACGTCGCCGTCATCGGCTGTCAGCCCACAACTGGGGAGTGCTGAGCGCGCTGGCCCAACGCACACGTA
TCACCAAGACGGCATTGTTGTTGACAGTCTTTAGCCAAGTGCTGGCACGTTGGAGCCTTAGCCCGACGTTTACGCTCAAT
CTGACGTTGTTCAACCGCCCGCAGGGTTACCCCAACGCAGAGGCAGTTATTGGTGATTTTACCGCTGTCAGCTTGCTGAA
TGTTTGTTACGACAGCCAGCACTCTTATGCCCACAACGCTCAGCGTATTCAGGTGCAACTGTGGGAAGATCTCGAACATC
GTCGTTTCAGTGGGATCCGCGCCAGCGAGGCGCTGATCCATAGCGGTCGTTTCCATGCGCCGATGCCGGTGGTATTCACT
AGTATGTTGGATATCGACGGGGAGACGACTGCGCAAGACCCTCGGGACACAACCCGTTTTACTCTGTGTCCGGACGCCAA
TATTACCCAAACACCGCAGGTGTGGCTCGATCACCAGGTGATCGAGTTGGCTGGGGAGTTGCATTTCAACTGGGACGCGG
TCGAGCAACTGTTTGATACCACGCTGCTGGATCAGATGTTTGGTGCTTATTGTCATGCGCTGCAGGCGCTGGTTGCCATG
CCGCAAAGTTGGTGGGGGGTAAATAGTTCTCTGGCGCTGCCCACCGTTAGTGCACCGGTCACGCAGGCTCCTGCACCTAC
GGCCTTGTTGCACCATGGATTACTGCGTCAGGCAGCACTGACGCCACAGGAAACTGCGCTGATCAGTCCTATCCGTGAAT
TGACCTATCGCCAACTGTCGACGGCGGCGGATCATGTGGCCCGCGCCCTGTTAGCGCTGGGCGTGCAGCATGGCGACCGC
GTGGCGGTGGTGATGGAAAAAGGCTGGCAGCAGATTGCCGCCGTACACGGCATTTTACGACTGGGTGCGGTCTATCTGCC
AGTGGATCCGGTGCTACCGCCACAGCGTCGCCAGCTTTTGCTGACGGTGGGCGAGGTGCGGGTACAAGTAACGCAGCCGG
GTCTCACGCAATTGGAGCCGTCGCTGCCCGTGCTGATCATCGACGACGGAATGCTGGACACGCCTGCTGCGCCGTTGCCT
GAAGTGGCTGGGGATGTCACGGATCTGGCCTATATCATTTTCACTTCCGGCTCCACCGGTACCCCGAAAGGAGTGATGAT
CGACCACCGTGCGGCCATGAACACGCTGGAAGACATCAACGAACGCTTTGGCCTCAATGCGCAGGATAGGGTGTTCGGGC
TGTCATCATTGAGCTTTGACCTGTCGGTTTACGATGCCTTTGCGCCTTTTATGGTGGGTGCAGCGCTGGTACTGCCGGAA
GCAGGACGGGAAAAAGATCCGCGTCATTGGCAGACAGTTATGGCACACGGTCATGTAAGCGTCTGGAATGCAGTGCCCGC
ACTGATGCAGATGCTGTGCGAATACCACAGCGGCGATCGGATGAGTTATCCGACGTTGCGTCTGGCACTGTTGAGCGGCG
ACTGGATCCCGCTAACGTTACCGGAGCAGATGCGCGAGCGGCTCAATGAAACGATGGACATCATCAGTCTGGGTGGAGCG
ACCGAGTGCGCCATCTGGTCGGTCTACTACCCGATAGGTGAGGTGGAATCGACGTGGACCAGTATTCCCTACGGTCGGGG
CCTGCGCAACCAGCCAGTATACGTGCTAAATGCGCAACTGGAGGAATGTCCGGTCGGGGTGGAAGGAGAGATTTGCATTG
GCGGGATGGGGCTGGCACAAGGCTACCTGAACGACGCAGAGAAAACGGCGGCGAGCTTTGTCTGGCGCGAAGCGAGTGGT
GAGCGAATTTACCGCACTGGGGATCGCGGGCGCTACTTTGCTGACGGGCAAGTCGCCTTTTTGGGGCGCAACGATACCCA
AGTGAAGGTGAATGGTTACCGTATCGAACTGGGGGAAGTCAAAAGCCACCTTGAACAGCTCGACAGCGTAGGGAGTGCCG
CCGTGGTGTGCCACCAGGGACAGCTGTATGCCTTTATCACTGCCGCAGAAAACCTGCATCCTGACGATACTGACGCCCTG
TTAGCGCGTGTTCGTGCTCAGTTAGCCGTGCAGTTGCCGTATTACCTGCTGCCCCAACATTTCTTTCTTCTCAAGGTGCT
GCCGATGACAGGCAACGGCAAAATTGATCAGGCGGCAATGGTTCAAGAGGTTATCCAACGTATGTCGCAATCTACATCAC
AGAAGTCGAGGGCCCTCGCGCACGCCTCGCCCTATGAACAGCAGGTGGCCGCTCTCTGGTGCGAGGTACTACAACGAGAA
CAGATCGGACTGAATGACAACTTTTTTGAAGCGGGGGGCGGCTCAATCCAGATCGTGCTGTTGCATCGCCGTATTGAGGA
GATTTTTAAGGTTACGGTACCTATTGCTGAGCTATTTCGCTTAACCACCGTGAAAAGAATTGCCGGTTATTTGCAGGCTA
TGCAGGACAATGCACGGGCGGTGAATCAAACACAGCAGCGTGATGCTTCCCGATCCCGCGCCCAGCAACGACTTGTACGT
CGTCACCAGCGTCAGCGTTAA
>clbI|locus_tag=ECOK1_RS11370|product="colibactin polyketide synthase ClbI"|protein_id=WP_000829570.1
ATGGCAGAGAATGATTTTGGTATAGCTATCATTGGGATGGCGGGGCGTTTCCCTCAAGCCGATACGGTACAGGCGTTTTG
GGAAAATCTTCTGGCAAGCCGAGAGTGCATTTCCTTTTACAGCGATGAGGAACTGCTGGCGATGGGAATCAGTCCTGAAT
TTGTTCAGCACCCAGATTACGTCAAGGCCAAAGGGGAGGTAGCTGACATCGATAAATTTGATGCTGCTTTCTTCGGTATC
GCACCCCGAGAGGCGGAGCTGATGGATCCTCAGCACCGTGTCCTGTTGGAAACCGCGTGGGCAGCCTTCGAAGATGCGGG
CTATGTGGCTGCCGATTATCCGGGGGATGTGGGTATTTTTGCTGGCAAAAGCATGGATTCCTATTTGATGCTGAACTTGA
TGCCGCACTTTAAACGCGTTTTCTCTTCTGGCAGTTTGCAGGCGGCCATTGGTAACGACAAAGACAGTATCACTACTACC
ATCGCCTATCACCTCAACCTGCGCGGCCCGGCGATCACGGTGCAGACTTCCTCATCGACATCCTTGGTGGCGGTGTGCGT
GGCATGCCAAAGTCTGTTGACTTGGCAGTGTGACATGGCGATTGCTGGCGGAGTAACGCTGGGGCCACCAGCAAAAACCG
GCTACTTGTCGCAGGAAGGTGGGATCACCGCCGCCGATGGCCACTGTCGGGCGTTTTCCGATAACAGCAGCGGATTTGTG
CCCGGCACCGGCGCGGGGCTGGTGGTGTTAAAGCGTGTTGATGAAGCGCTGCGTGATGGCGATAACATCTATGCGGTCAT
CAAAGGATTTGCCGTCAACAACGACGGTTCGGAGAAGATCAGTTATACCGCGCCGAGCGTGGATGCCCAAGCGCGCGCCA
TTGCTCAGGCACAGCGGTTGGCAGGTTTGACACCGCAGGATATCACTTATGTGGAAGCCCACGGTACCGGTACGCGTTTG
GGCGATCCGGTTGAGTTTTCTGCGCTAAGCCAAGCCTTTGCGGGCGCGTCACAAAAGCAGTACTGTGCGCTGGGGTCGGT
AAAAACCAATATCGGCCATTTGGATACGGCAGCGGGCGTCGCAGGGTTGATAAAAACCGCGCTGGCAGTGCAGCAGGGAA
TAATTCCCGCAACATTGCACTTTGAACGGCCCAATGCACAGATCGATCTGACCAATAGTCCGTTTTACATCAACACTACC
TGTCAACCGTGGCAACCGGAAAGCGGCATCCGTCGCGCGGGCGTCACCTCGCTTGGCATGGGCGGCACCAATGCCCATGT
TGTGCTGGAACAAGCGCCAGCCGTTGACTTGCAAGCGCGAGCGCCTGTACCTGCCTACAGTATTTTGCCGTTTTCTGCCA
AGACCGACAGTGCCTTATCCTCGGGGCTGGCGCGTTTTGCCGATTTTCTGCAACATGAATCGCTGCCGGATAGGCGGGAT
CTGGCGTGGACACTCTCACAGGGACGTAAAGCCTTCGCACATCGCGCCGCGCTCGTAACCAGAGATCTACATGCTGCCGG
GACGCTGTTGCAGCAGGCCGCGACAGCGCCGTTTGCTCGTGGTGTAGCGCAGACACAGCTCGGGCTGGGGCTGTTGTTTT
CCGGGCAGGGTAGCCAATATCAGCGCATGGGCCATCAGCTCTATCAGGTTTGGCCGGCCTACGCCGATGCCTTCGACCGT
TGCGCGACGTTACTCGAGCGTGAATACCAACTGGATATCCGCCATGAGTTGTTCAGAGCAGAAGTCTCGTTAGCCCAAGG
CGAACGCCTTGCGCAAACCTGCCTCACACAACCGCTGCTGTTCAGCGTCGAGTATGCCTTAGCCCAATTGTGGCTCAGTT
GGGGAATCACGCCAACGGTAATGATTGGTCATTCGCTGGGCGAATGGGTGGCAGCGACGTTGGCAGGCGTGTTCTCTTTA
GAGGATGCGTTGCGCTTGGTGGCGCGTCGAGCAGAGCTGATGCATCAGGCACCAAGCGGTGCCATGTTGATGGTGGCGCT
GCCCGAAGCACAGATTCGCGCACTGATTACCGCCCCGCTGGCGATTGCCGCTGTTAACGCCCCTGACTATTCGGTTATCG
CCGGGCCTACGTCGGAGATCCTCGCCGTCAGCCAGCGTCTGACGGAGCAGAACATCATCAACAAACGATTGCATACCTCT
CATGCCTTCCACTCTAGCATGATGCAAGATGCGGCGCAGGCGCTACGTCAGGCATTTGAGAATGTACGACTGAACCCGCC
GACGCTCACCATCATCTCTACCGTAACCGGCGCGCACGTCAGTGCCGACACTCTCACCACACCGGACTACTGGATTGAAC
AGATGCTGATGCCTGTGCAGTTCTCCGCTGCACTGCAAGAGGCGCAAGCTACATTTGATGTCGATTTTCTGGAAATCGGG
CCAGGTGCCACCCTGACCCAGCTGACCAACGGTCATGCATTAGGTGATCGTCTCGCGTTCAGCTCGCTGCCAGCAGGTGC
CCGCAGCAGCGATGAGCACAAACATATCTTAGATACCGTGGCAGCGCTTTGGGTGCGAGGGCATAACATCGATTTGTCTG
CGTTTGCAGGTGAGCAACCGCGCCGTGTCTCTCTACCGACCTACGCCTTTGACAAAATCCGTTACTGGGTCGACAGTCCA
GAAGAACAGAGGAGCGCCGTAACGCCGGTGGCGGACGCGGGAAGTGTCATCCCTAGCGAACCGTCGGTGCGCCGTCAGCC
GCGTCCGGCGTTTTCGGTGCCTTACGCGGCTCCAGAGAGCAAAACGCAGCGCGGCTTAGTGGCGATTTGTGAAGCATTGC
TGGGAATTGACGGCTTGGGCATTGACGACAACTTCTTCGAAGCTGGCGGACATTCATTGATGCTGGGCATGTTGCTGGCG
CAGGTACAGGAACGGTTCGCCGTCACTCTTTCCTTTTTCGACGTGATGGAGGATGCCAGCGTGCGCGCGTTAGCGCAGTT
GGTCGAGCAGGAGCAGCAGGATGATGGAGGGTCCGCACTTGCCGTGCTAGTTAACGACATGATTAATGAGTGA
>clbH|locus_tag=ECOK1_RS11375|product="colibactin non-ribosomal peptide synthetase ClbH"|protein_id=WP_001304254.1
ATGGAACAGCAAGGGATTATGAGACAGTTGCCTACCGACGACCAAACGATAGTCGACTATTTGTATCGTATCGCCGGAGA
ATATGGGGAAAAAGCCGCTGTATTGATGGGGGACGCGGCGCTGAGCTATCACGATCTTAATGCACGCTCTAACCAACTGG
CGCATTATCTGCGTGGGCTGGGGATCGGCGAGGATCGTGTGGTAGCTATCCGCCTGCCGCGCGGCATGGCAATGCTGATT
GCCATTTTCGCTATTGTAAAAGCTGGTGGTGCCTATTTACCGCTGGCGTACAATGCACCGCGCAGCCGCATTGAAAATAT
ACTGAGCAACAGCGGCGCTGTTTGTCTGATCGGTACTGACGATGGTGATCGCTGGCCGATTCCTCGCGTCGAAATCGACA
GCGCGGCGGTCAGTGCCATGCCAACGACGGATCTGCGTTACCGACCACATGCGCGGCAACTGGCGTATATTATTTACACC
TCCGGTTCCACCGGTGTCCCTAAAGGGGTGGCGACGGAACATGCAGCGCTGCTAAACCGAATTGTCTGGATGCAGAACGC
TTATCCTATCAGTTCTCAGGACGTGCTGTTTCAGAAGACGGTGTACACCTTTGACGTCTCTGTCTGGGAGATGTTCTGGT
GGGCGATGTACGGCGCATCTGTAGTGCTGTTACCGTCCGGACTGGAGAGCGATCCGCGAACCTTGGCTCGACTGATTCAG
CGTCACCGCGTGTCGGTTGTGCACTTTGTCCCTTCGATGCTGAACCTGTTTGTCGAGTATCTGGAGATGAAACAGGATCC
TCGTTTGACCGCCTCATTGCGATTAGTGTTTTCCAGCGGTGAGAAACTCACGGTCCACAGTGTGGCTCGCTTTTATCAAT
CGGTGGCGCAGGGTGATCTTATAAATCTCTATGGCCCGACCGAAGCAGCAATCGATGTCAGTCATCACCGCTGCCTGCGC
GGGTACGACTACGACGATATCCCTATCGGTCAAGCGATTGACGGTTGCCGACTCTATGTGCTGGATGACCATGGTAATCC
GGTAGCAGACGGCGAAGAGGGCGAACTGTATCTCGCTGGTATCGGGCTGGCACGTGGCTATCTCAACAACGTGGCGTTAA
CTGATCGCTGTTTTACTATACATCCAACTTTGCGCCATTTAGGGAAACCGGAGCGGCTGTATAAAACTGGAGATCTGGTG
TGGCGCGACGGGGAAAGCCAACAAATTCATTACATTGGCCGTAATGATTTTCAGATTAAAATTAGAGGGTTGCGCGTTGA
ATTGGGAGAAATCGAAGCCCATGCGATGCGTTTCCCGGGGGTACAGCAGGCAGTCGTGGTGGCGGATCAGGATGATCCCG
ACAATCAGTTGATTTACGCTTTTGTCGTCAGTAGCGTGCCGCTCAATTTGGCGGCCTTAATGGACGCACTGTCCAAAAAC
TTGCCTGCCTACATGCTGCCGAACCGTTTGTTGGCAATGTCAGAGTTACCACTCTCCGACAATGGCAAGTGCTGTCGTAA
AACGTTGCTCGACTTGGCGCGGGCGTACTCAGCCAGTCGCGTCGATTTACGTGAAACTCCCGCCGTGCGCTACCTACCGT
TGTCATCGGCTCAATCGTCGATGTGGTTTATGCAACAATTGGCGCCGCATACTGCACTATACAATAACCCCACCGCCTTG
CTGCTTGAAGGAGAACTGGATCGCACGCGGATGGACGGCGCGATTCGTCAATTGATGAGTCGGCATACTCTGTTACGTGC
TATGGCGGAAACCCACAATGGACAACCAGTATTGGCGGTGCCTCAGTGCGTATCGTCGCAGGCGTTGCTGACCATAGTGC
CACTCCCCTCGGTGAGTGATGATAACGCGCTACAGGCGATGATCAACCAGCGTGCGGCACACCCCATGCCCTTAACGTCA
GGCACACCGCTGTGCCGGTTTGAACTGTTGACGCTCGATGACGATCGTAGCGTATTGTTGATTCATCTGCACCACATCAT
CAGTGATGGCTGGTCGAAAGGCGTTTTGTTACGCGAATTGCAGGCCGCATATAACGGTGAATCGCTGACGCCAGAACCGT
TGTTGGAGTATGCCGACTACATGGAGTACCAAGAAGAGTGGCGTCAGAGTGACGCCTATCAGGACGCGATGCGTTACTGG
CAAAATACCCTGGCGGGGACGTTGCCGATTCTTGATATCCCCACCGATCAACCGCGTCAGAAGGTGGCACGTTACCAAGG
CGCGTTTGTTGCCTTCGCATTGTCTGCCAACACATGCGAGCGAGTGTTGGCGGCGGCGCGTGCGCAGCGCGTGTCGTTGT
ATAACTATCTGCTGACCGCCTTCGTCCTCCTGCTGCATCGTAATGCGCGTCAACAGGAATACATCGTCGGTATGCCGATT
GCTGCGCGGCTGACGAAAGAACAGGAGCATATGATCGCGCCGCTGGTCAACGTACTACCGCTGCGCTTACCTCTTGACGA
AGCGGCATCGTTTTCCGAGTTAGTACAGACGATCAGAGGTATTCTGTTTGCCGCTTTCAGGCACCAGCGTCTCGAATTTA
CCGACATAGTGCGCGCAGTGAATGTGGATCGCAGCGCCGGACATTTCCCAATATATCAGTGCATGTTCCAACTCGACAAT
ATGCCTCTGGCGAGCCCGACACTAAACGGTGTCAACGTTACACCATTATTGTTGGATACCAGTGCATCTCAGGTGGATAT
TTCGCTAAGTATGCAGCATATCGATGGGCGCATCACCGGCACTTTCGAATACGACGCTGGGTTATACAGTGCGGATCGTA
TTCAGCACCTGGTGGCGCAGTGGAGAGAACTGCTAGATGAGGCCAGCAGCCAACCCACGCAGTTAGTCCGCGATTTGATT
CGTTTCACCCCTCGAGAGCACGCTTGGCTGGCGCGGCACAACGCCACTGAAGTTGCTCTGCCGCCCGTAGATAACCTGCT
GGCGCTAGTGTTACCGCACTGCCAGCAGCGCCCTACACAGGTGGCTTTGCGCCACGCTGACGACGCCATGACCTATGGCG
AATTGCAACAGGCCACGATGCAGATGTGTACTTGGCTGCGTGCGCAAGGCGTAAAACGCGGAGAATCTGTCGCACTGCAA
CTGCCTTTTTGTTTCGAATTGATTATCGCACAATTGGCGATCCTCTCTTTGGGGGCGAGCTATGTGCCGCTGGATGGTAA
CGCGCCAGCGGCCCGCAATGCCCTGATCTTGGCGCAGGCAACGCCGTGCATGCTGCTGGTGGCGCAACCGCTGGAATCCC
CTCATGGGCTGACGATACCTTGGGTGCTAGTGCCTGACTGGCGTAGCCTGCTGACAGAAATACCGAACCTGCCAGTTAGT
GTTGCGCCAGATGCTTTAGATTGCGATGCGGTGGTGATCTTTACCTCCGGTACTACCGGGCAGCCCAAAGGCGTCCGACT
CAGCCAACGTAATCTGGTCAACTTAACCGCATCCTTTATATCCAGCTATCAAGTGACGCATCAGGATGTTTTGCTACCCA
TTACCTCAGTCGCGTCTGCTAGCTTTGTCGGGGAGGTACTGCCGCTGCTCGCCGCTGGCGGTACCTTAGTATTGGCGCAA
AAAGCGCAGAGTTTGGATAGTGATGCGCTCATTGCGCTGCTGGCATCTCAGCGGGTGACTATCCTGAGCACCACCCCATC
GCTTTCTGCCAGCCTCTCTGTGCTGGCTCAGTCGATGGGATCGCTGCGCTTGTTTCTGTGCGGTGGTGAAGCGTTAGAGT
ATGAGCAGATAGCGCCGCTTCTGCCGCACATGGCAGTGGTTAACGGTTATGGCCTGACCGAAAGCGGTATCTGCTCGACC
TACTTTCCTGTCGCAAAGCGTAGGGAGCAAGAAACGGGAGCATTGCCCATTGGCCGCCCGATTCAGAACACCCAAGCTTA
TGTGGTGGATGCATATAATCGTTTGGTACCGCCAGGTGCCTGTGGAGAACTCTGTTTCTCTGGTCTGGGCATTTCGCCCG
GCTACCTTGATGCACGACAGGATCCCGAGCGCTTTGTCGAGTTGCCGGAATACCCTGGCGTTCGGGTGCTGAAAACTGGC
GATCGTGCTCGTTGGGCAACCGACGGGATGTTGTTCTATCTCGGCAGACAAGATCGCCAAGTGCAGATCCGTGGATACCG
AGTTGAACTGGGCGACATCGAAAGCCTACTGAAACAGCATCCGGATATTGCTGATGCGTGGGTCGATGTGCGACGCAATG
CGGCGGCAACGCCGCTACTAGTGGCCTTCTATTGCAGCGTCAACGGCGTTGCGCTGGATGCTCAGCAATTGCGCGTATGG
CTCAGCCTGCGGCTTCCGTTGCATATGCTGCCGTTGCTCTACGTGCCGCTGAGCGCCATGCCGCTAGGTGTAAACGGCAA
AATCGATCCCCAGTGCCTGCCGCTGGTCGATCTGCGGCAGTTGGAAGGGCCGGGCGAGTATGTCCCTCCGGCAACCGAAC
TGGAACAGCGTCTGGCGGAGATCTGGCAGCAGTTGCTTGGCCTGGAGCGTGTCGGCACCACCACAAATTTCTTCGATCTC
GGTGGACACTCACTTCTGCTAGTACAGATGCAGCAATACATCGGGCAGCAGTGCGGTCAGCACGTGGCGTTGGTTGACCT
GCTGCGCTTCACTACCATCAAACGCTTGGCGGAATTTCTGCTGGCCCCGGACGCAGCGCAAGGGACCACAGGAGATCAGA
CACAACTGCGTGCGGCGAAGCAGCGTTTGGCCTTTGGTCACACGCGCTGGGCAGCCACAACCGACAGTCATCACTGA
>clbG|locus_tag=ECOK1_RS11380|product="colibactin biosynthesis acyltransferase ClbG"|protein_id=WP_000159201.1
ATGACGAAGGATGTCGCACTGATGTTCCCTGGCTCCGGTTCGCAATATGTAGGCATGGCACGGTGGCTGTATGAGCGTTA
TCCGCAGGTGCGTACTCTGTTTGATGAAGCTAGCCAGATCACGGAACGGGACATGGCAGCGCTGTGCCTGTCGGGTACTT
TGGTACAACTTGCTGAGCCGACGGCAATGGCGCTGGCTATCTATACCACCAGCGTGGCCCACTTTGTCGCGTGGCAGCAG
TTTTTGGCGCAAACCGGTGTCCATGTCAACCTACGTTATATGTTGGGTCATAGTTTGGGCGAATATGCTGCGCTGACCTG
TAGTGGTGCGCTGAGCTTTTCCCAAGCACTGGCGCTGGTGGCGATGCGTAGCCGTTTAGCCAGTGAGATCGCCCGCGAAA
TGGACGCGAGTACCACTATCATCAAGCAAGGGAATCAGGCACTGGTGGCAGCGGCGTGCGAGGTGGCGGAGCGTGAAACC
CGACAGCAGGTCGGTATTGCCTGCTTCAATTCGCCGCAACAGTTTATGTTATCCGGACAAAACTCGGCCATTATCGCCGC
CGAGCAATACCTGCTGGATCATGATCGCCAAGTCGAAGTAGTGCCGCTGATTGGTGGTGTTCCTTACCACAGCCCACTAT
TGAAACCTTGCGGACAGCAATTGCGCAAGGCGCTGGATCGCTGCGAATGGCGACGTCCGTGCTGCCCAGTGATCTCCAAT
GTCAACGCTCAACCCTATCCCGATACGGTCACGCCAGTCCAGTGGCTAGAACAACAGCTCTCTCAGCCAGTGCAGTGGCA
GCGCTCTCTCACCTACCTGACAGGACACTTGTCACCGATCGCGATAGAGATCGGTCCGCAAAGTGTGCTGAAAAACCTGC
TGCTGGAGAATCGCTATCCAGCACCAGTTTACGCATTTGACAATCGTCATGATCGTGCGCAACTAGCATTGGTGCTGGGG
GATAACATGGCGGTGAAGACCGATCCGGAAGCCGTGCGCCGCCAACGCATCACGCTGCTCACTAACGCCCTGACAGCCAC
ACGCCATCACCGCGCCGCCGATGTGGCTGCCAGTGCGCAATTGAAAGAATTGCTCAGTCGTTTTTTTGAGCGCATCCAGC
AGATTGAGCAGCGCGGCACATCCAGCGAAGAGGACATTGCTTTTTTGCATGAGCTTCTTGAACAGGGATTTCAACTCAAA
GGCAGTAGTCAGGCAGAAATCGACGCCTGCCACGCGCGGTTGGCTTCCGACAACGGCGGACAGGCGTAA
>clbF|locus_tag=ECOK1_RS11385|product="colibactin biosynthesis dehydrogenase ClbF"|protein_id=WP_000337350.1
ATGTGCACTGAAAATTATGAGCTGGCTCAGCAAGAGGCAGTCCTGTTTGCCAAACAACATCTCGCCCTGGCTGCACAGAA
TATTGAACGTCAGCAGTTTATTGTGCCAGACATTATTTCTTGCGTGGCGCAGGCCGGGTACTTAGGTGCGTCAATCCCCC
AAAAATATGGCGGACGAGGTTACGATTCTTATCAACTGTGCGCTTTGCATGAAGTGATGGCTGGGGTTCACGGTTCGTTA
GAAAATCTCATAACAGTGACTGGCATGGTCAGCACGCTGCTGCAACGCGTGGGCAGCGCAGCGCAAAAAGCCCATTATTT
GCCAAAGCTGGCAACGGGGGAATTGATCGGCGCGATTGCCCTCACAGAGCCGAATATCGGCAGTGACTTAGTGAACGTGG
AAACAGAATTACAGCAGGATGGCGACGGTTGGCGGCTGAACGGGAAAAAGAAATGGATCACGCTAGGGCAGATTGCTGAT
TTTTTTATTGTTTTAATCCACTGTGGTAATCAATTAGCGACAGTGCTTATCGATCGCAATACCGACGGCTTTACTATCAC
TCCACTCAACGACATGTTGGGGTTACGCGGCAATATGTTGGCAGAGCTGCATTTTAATGACTGCCGCCTGAAGGAGGATG
CATTGCTCGGTCCGCTCACCCCTGGGGTACCGCTGGCGGTGAATTTTGCGCTCAATGAAGGGCGGTTCACCACCGCTTGT
GGCAGCCTAGGATTATGTCGGGCCGCTGTGGATGTGGCAGCGCGCTACATCCGCCAGCGTAAACAGTTCAAGCGGCGGTT
ATTTTCTCATGGCATTGTTCAGCACTTGTTTGCCACAATGCTGACCCAAACGCGCAGTGCGCAACTAATGTGCTTCAGCG
CGGCGGAATACCGCGAAACGCTGCACCCGGCCATGATAAACCAAATCCTGATGGCGAAGTATGTCGCTTCCAAAGCTGCG
GTGGACGTGGCCGGGAAGGCGGTGCAACTGCTCGGTGCGAATGGTTGCCATGCCGATTATGCCGTCGAACGTTACTACCG
CGACGCCAAAATCATGGAAATCATCGAAGGGACATCGCAAATTCATGAAATCCAAATTGCGATGAATTACATGATGGGGA
GTGAAGCATGA
>clbE|locus_tag=ECOK1_RS11390|product="colibactin biosynthesis aminomalonyl-acyl carrier protein ClbE"|protein_id=WP_001297917.1
ATGAAAAAGCAAGATATGAAAGCCGCCATTCGGGAATTTCTTTCACGCTCATTACGTGGGCATACGTTGAACGATGATGA
CGATATTTTTTCTCTCGGGCTTGTCCATTCGTTATTTACTGTGCAAATCATACTGTTTATAGAAAAAAATTTTCAGGTTG
AGCTGGAAGTGAGTGAGTTGAAAACAGAACAGATTGCTACCGTCAATAAAATAGTGGAGCTCATTCAGCGACAAACAGGC
CTGGAGTAA
>clbD|locus_tag=ECOK1_RS11395|product="colibactin biosynthesis dehydrogenase ClbD"|protein_id=WP_000982270.1
ATGATGAACGTGGCGGTAATAGGTGCAGGAGTAATGGGAACTGGCGTCGCTCATAACATGGCGCAATACGGCATATCAAC
TAACGTTGTGGATATTTCTCAATCTCAGTTGGATAAATGCCGACAGATGATCGAAGCGAACTTACGCTTATATAATTTTC
ACCCGCAGCATAAAAAAAAGACGCATAGCACAGCGGAGATAATGGAAAATATCCGTTTCACAACTGAGTTGGACGACATT
GTAGAATGTGATTTGGTGATTGAGAATATTACTGAGGATATAGAGAAAAAAAATGCACTATACACACGGATGAATACGAT
CTGCGGCGCGTCGACAGTGTTTGGTGTTAATACGTCCGCCATATCTATCACTGCGTTGTCAAAATTAATGCGACATCCGG
AGAATGTAGTCGGCGTCCATTTTATGAACCCGGTACCGCTGATGCACACCGTCGAATTAATCCGTGGTGTACATACTGCA
GAGCGTACACTGAACATATTTCACCACTTATTTGCTCAGTTGAATAAAACCGGCATCGTGGTCAATGATTCTCCGGGCTT
TGTCACTAATCGTGCCATGATGATTTTTGTTAACGAAGCCATATTTATGGTGCAGGAGCAGATCGCCCGTGCTGAGGATA
TCGATACGTTGTTTAAAACCTGCTTCGGGCACAAGATGGGGCCACTACAAACTGCCGATTTGATTGGCTTGGATACGATT
TTGCAATCGTTGCAGGTGCTATATGAAAGTTTTAATGATGATAAGTATCGCCCCAGCTTTTTATTAAAGAAAATGGTCGA
TGCAGGGTATTTGGGCGTGAAATCAGGGCAGGGGTTTTATCGCTATCAACAGACGTACGCCGAGCAGTGA
>clbC|locus_tag=ECOK1_RS11400|product="colibactin polyketide synthase ClbC"|protein_id=WP_001297908.1
ATGGAATACGCAAGCGAAATGAACGGCATGGAAATCGCCATTATTGGTATGGCGGTCCGTTTCCCGCAGTCCCGGACGTT
ACACGAATTCTGGCATAACATCGTTCAGGGTAAAGAGTGCGTCACCTTCTTTAGCGAGGAGGAGTTGCTGGCCGAAGGCG
TCGAACAGAGTACTCTGGACAACCCGGCCTATGTACGGGCCAAGCCCTATATCGAGGGCATATGCGACTTTGATGCTGCA
TTTTTCGGTTACAGTCACAAAGAGGCGCAGACTCTGGATCCGAAATCCCGCGTATTACATGAAGTTGCCTACCATGCGCT
GGAAGATGCAGGCTATGCCCAACGTACCAGCGATCTGATCACCGGGGTATTCGTGGGGGCGTCAGAAGATGTGGATTGGC
TACGGCGTTCGCTGTCACAGATTGGCGGCGATGCGCTGAATCGTTTTGAGTCTGGCATCTATGGTCATAAGGATCTGCTC
GCACATCTCATTGCCTACAGTCTCAATCTCAACGGTCCGGTGTATAGTCTCTACACCAGTTGTTCGACTTCTCTGAGTGC
AACGCATATCGCTTGCCGCAGCTTGTTGTTTGGCGAATGTGATCTGGCGTTGGCGGGTGGAATTACTATCGATTTACCGC
AGAAGTCAGGCTACTTCTGTCAACAGGGCATGATCCACTCCACCGATGGCCACTGCCGTCCTTTTGACAGTCAGGCTTCT
GGCACCCTGTTTGGCGATGGCGCGGGTGTGGTTGTGCTTCGGCGTTTGGAAGATGCTCTGGCAGCGGGCGATCGCATCTA
TGCGGTGATCCGGGGTAGCGCGGTCAACAATGACGGTAAACAAAAAATCGGTTTTGTCGCGCCTGGTCATGAGGGACAGA
AGGCGGTCATTTGTGCGGCCTGTCATCTGGCAGAAGTAAGCCCAGAAAGCATCGGCTACGTTGAAACCCACGGTACCGGC
ACCCGTATTGGCGATCCTATCGAGTTCGCTGCGTTGACGGAGGCGTTCGATACTTCACACCGCCAATACTGTGCACTAGG
GGCTGTAAAGGCGAATATTGGCCACACCCACGCGGCGGCGGGCGTGGCTGGGTTAATCAAGACGGCGCTGGTACTTCATC
ACCGGACCATTCCGCCGCTCGCCAACTATCAAATGCCTAACTCGAAGCTGGATCTGGCGCATTCACCGTTTTATATCCCG
ATACAGCCGCAGGAGTGGCCCGCATCGCGGATGCCGCCCCGCGCTGGCGTCAGTTCTTTTGGCATTGGCGGTACTAATGT
GCATATGATTTTGGAAGGGCTGAATCCTGCGGTGCGCGATGACCATGACCAAGTGCGAGCACCGGTGTTTATCCCTCTCT
CCGCGCCGTCTTTCGAGCAGTTGGATGAGCTGACGCAACAGCTTACCCCGTTGCTGGCTACCCTTGATGCGTCAACGCTA
GCCTACACACAACAAGTGGCGCGCCCCGTGTTTGATTGCCGCCGAGTGATACAAGTGGAAAACGATGGTACGCAAGCGAT
GCTGGCATCGCTGGATAACCTAATGCCCGACGCTCCTTGGGGCCTACACTGTCCAGATCTACGTACTACGAACGATTGTA
CTTACGCACAGTGGCTGGCGCATTCGGCACATTATCAACGCGAAGCGACTGCTCTGACGGCATTACTCGACGGCATGAAT
ATTCCACCCGCTTATTGCCACGCTGAAACGTGGGCGGCACAAGCGAACAGCAGCCTGCTAATCAGAGGCTGCCAGACTAT
CGCCGCGCTAAAAACCTGGATGAACCTGCTACCGACATTAACACTGCTGTCGGGTGCTGGAACAGGCCTTTTGCCTGCCG
CTGCAGCCAGTGGCATGATTGCGACGCAAGACGTGTTGCATTTGCTGTGGGAAATGGAGCAAAAGGCGCTTCATCTCTGG
CTTCCTGAGCGCCATGAACCTATCCCCGGCTACGTGCTGGCTTGGCAAGGAAATCCCATCACCGATGCACAGCGTAACGA
CAGAGGGTTTTGGAGTGAAGCGCTGTTGGCAGATACCCGAGAACTGGGGGAGGGCGTTCACAGTATCAACTGGGTTAGGC
TGCCGCCGGAAATAAGAGAAGACGTTGATGTATTGCGCTACGTGGCGCAACTGTGGTGTGCAGGTATCAATGTGGATTGG
GCCGTGTGGTACGGCACTCCGCTGCCGCAACGCGGGAGCGCATCAGCATATCCCTTCGCACACAACCACTACCCATTGCC
TGGACGGGTAATGGGTAGTGTGGAGACCCAACCCGAAGCAGGACCCGAAACGCACCACCCTTATCAGGCACGTCCCGTGT
TAAGCGTACCTTTCGTAGCCGCACACTCGCGGGGTATGCAGTATATCACAGGTCTGATGGAACTGTTGCTGGAAATATCG
CCGGTCGGGGTGGACGACGACTTTTTTGAATTAGGCGGGCATTCGCTGCTGGTGACGCAATTGACCTCCCGTTTAGAACG
CGATTTCAACGTACATATCGATCTTTTGACCCTGATGGAAAACCCCAATCCGCGCAATATCTACGCGCATATCGCGGCGC
AACTGGGGGGCGAAGACAACCTCGAAATAGCCTGTCAGTAA
>clbB|locus_tag=ECOK1_RS11405|product="colibactin hybrid non-ribosomal peptide synthetase/type I polyketide synthase ClbB"|protein_id=WP_001518711.1
ATGGATAATACCTCTGGAGATTTTCCATGTAATAAGATGGACACGCGTAAGCAGTTACCGCTAACACCAAGTCAACAGGG
GTTTTTATTCCATTCCTTAAAGGATAAGAAAAGGAGTAACTACCATGAGCATTTTACATGCATTTTTTCTCAGCATGTAG
ATAGCGCCCACTTCAAGTGGGCGCTGGAAACGTTATTTCGAAAGCATGAGTGTTTTCGCACTGATTATAACTGGGAGATT
GATGAGCGCCCTTGTCAGGTGGTGAAGACCGATGTGTTGCCGGATATATATGTGTTAGACTGTGAGCAAGAGGAAATACG
TTTTCTACTAGCTAATGATGACATTATCATTCCTGTCCCGCAGGATGACGGTATTGATGCTATAATTCCTCAACTGCTAC
AGGCTGATTTAAAATACCCATTTTCCTTGAAAACGATCCCAGTCCGGGCCTACCTTATTCAGTCAACGAAAGAAAGTGCT
TTTATACTATCATACCATCATATTGTGATGGATGGCTGGAGCTTATCCCTTTTCATTAAACAGTTGCTCCAACTCTATGG
AGCGGCTGTGGTCAGTGGTGTGAGGGATGATAGCGCCATTATCCCCTCATCTCTGAAACCCCTTGTAGACACACTGTCGG
CCCGACGTCACACCTTTCAGCACGACTATTGGGCTGCATATCTTCGGGAGGGAACACCAACTTGTATCGTGCCGCTGTCA
CAATATCACACAGATACTGAAGCCGAGAACAATTCTTACGTTAATCAAACAAATCATGTGGAGATCAATTTGTCTCCGGA
TGTGTGTCAGAAAATACAGACGCTATGCAGCGATTATCGTATCACCCCCGCAGTAATCTTCTATGTGGCCTGGGGCATCC
TGCTACAACGTTGGTGCTATGCTGACGATGTGTTATTCGGCGCGACAATATCAGGGCGAAATATACCAATTGATGGTATA
GAAGAAACACTAGGGCTATTTATTAACACGTTGCCGCTGCGTCTGCGTGATGATGGGGCGACACTGTTGCAACACTTACA
ACGTATGCACCAAACACTAATAGCTCACTACAGCAATGAACATGATGCCTTAGCCAGCATACAACGGTTGGTACATAAAG
AAGGTCATGCTGGGGATCTTTTTAATACCTTAGTGGTGTTGGAGAATTATCCCGTTGATATGACATTATTGTCATGCGCG
TCGCCCGTGGCAATTCGCCATCTCAGTGTACATGAACAAACGCACTATCCGCTGACCTTGACCATCACTCAACAGAAGGG
ATTCCGTTTCAGTATTGCATATGCCCTTAACTACCTGACCAACAACATGGCGCAAGCGTTGCTGATGCACCTGAGTTATC
TGCTTGAACAACTGGTGGACAATCCGCAGCGCCCCATTGCTGCGTTGGTAAACTTGTCCCCATGCCAGCAGGCGCAGGTA
CTTCAACCCTATCTGGAACGCATGGCATGCCGGGATTGGGATAGTCAATCCAACGTCATCGAACAATTTCATCAAGTTGC
TGCGACTTCGCCAGCACAGGTCGCAGTGGTTGATGAATTGTGCGCGTTGACCTATTCGGAGTTGGCAGCACAAGCTGAGC
AGCTCGCGGCTTATTTGGTACAGCAGGGTGTTATGGTTGGCGATACTGTAGGCATAATTAGCGAACGCCGGGTAAACACC
GTGGTTGCCATCATCGCCATCATGTTGATCGGGGCTGCTTATGTGCCCATCAGCCCCGACTACCCAGTGGGTAGGATGCA
GGAAATTATTGATGACAGCGGCTTGGCGCTGTTGCTGGTACATGGCAAACCGCTAGATGCATTAAACGTTGCGCAGAGTG
ACCTCTGTGCATTTCCCGTCGCGCCCTCGGTGGTATTTCCGGTTATCACACCAGATTCTCGCGCTTATGTGATTTATTCA
TCGGGGTCGACGGGTAAGCCAAAAGGTATCGCGGTGGCGCACCGCGGTTTATTGCGCCTGATACAAGGCGACAGCCCGCT
GAAGGTGGAGAGCGGTGAGACAACGCTGCTGACCTGCCCATTTGAGTTTGATGTTTCGGTGTTTGAGATGTGGTCTACCT
TGCTCAACCACGGCAAACTAGTATTACTCAGCAAACAGGCATTACTTGATATCAATCACATTCGCCGCACGATCGCTGAT
GAACAGGTGGCGCGCGCCTGGTTTACCTCATCCTTGTTTAACTCCTATGTGGCAGAAGGTGCCGATTTCTTCGGTATGTT
ACAACACATTACGGTGGGCGGCGAAGCAGTATCTGCGTGGCATGTCAACGACGTGATGCAAAAATACCCGCATCTGGTGG
TGACAAACGGTTATGGGCCGACGGAAAACACTATTTTTACCACCGCATATCGTTTCAACGGGTTGCAACCCGCCCGAGTC
CCGATAGGATACGCGGTACCGGGCACCTCGCTCTACATTACCGATCTCCATGGGCATTTGTTGCCTATCGGTGCCACCGG
TGAACTAGTGGCGGGTGGAGTGGGGGTCGCCATCGGCTATCAGAACAACCCGGCGCTAAGTGCGACGGTTTTTGTCCCTG
ATCCTTTTATTCCCGGCGGTATGATGTACAAAACTGGCGATTATGCCCGGTTGCTGGATGATGGCTGTGTTGACTGTTTT
GGGCGTAAAGACGGTCAAATTAAGATCAATGGACAACGAATTGAAACCGGAGAGATCGAGCAGCGCCTGCTGGAGTGCTC
CGGCATTATCGAGGCGGTAGTGGTTCCTTACCGCGTACGTGAAACGCTGCATATTGCGGCAGTGGTCTGCGTCAATGATA
GCTATGATGAGGTGGAAGTTCGAGGGCAATTGGCTGACAGATTGCCGCCATTCGCTATTCCGGAATCCTTGGTGGTGGTG
ACGGAGATTGCAAAAAGCCATAGTGGCAAGGCCGACTTGGCGCAGTTGCGGTATCTCCTGCCCGCAACTCAGTGCAACGC
CGTGTCCACCACGATATCAGAGGTGCATAGTGACATGGAACATGCGCTGCATGCTATCTGGCAACGCGTACTTGATAGAC
AAGACATTGATAGCAATGCCTCCTTTTTCGCCCTCGGTGGCACCTCATTGGATACCATCAGGGTTAAAGGGGATATTAAG
CGGCAACTTGGCTTGGAGATTGATATTACCGATCTCTTTAAGTACCCAACGCTCACGGCGTTAGCACATTTTCTCGATAC
TGCCGTATCGCCGGAGGATGCAATTCCAACGCGTGCTGTTGTCTACAGCGACATGCCGGTGGCGATTGTCGGTATGGCGG
GACGTTTCCCCGGTGCGGCGAATATTGCAGCGTTGTGGACGCTGGTTGTAGGAGGGGAATCGGGATTAACACTGTTCAGT
GATGAAGAGTTGCGCGCGCATGGTGTGACACCTGACACGCTTAAACAAGCGAATTATATAAAAACCAAAGGGATTGTTGA
TGATCACGAATGGTTTGATGCGGATTTCTTTGGTTATACTCCCAACGAGGCGGAATGTATGGATCCGCAAATTCGCTTAT
TGCATCAGTGCTGCTGGCAAACTCTGGAACACGCTGGGTGCGATCCTGCCACCTTTACTGGTGCGATTGGCATTTATGCC
GGACTGCTGACATCCCCCCACTGGCTTAATGCGGTAATGCAAGACACTACCGACTCTACCGCCCTGTACAAGGCCAGTAT
CCTGAATATCCATTCCGTCACAGCATTGATTGCCCATGCGCTTAACCTCACCGGCCCTGCCGTGACGCTTGACACCGCCT
GCTCCACTTCGGCAGTGGCTATCCACCAGGCCTGCATCGCACTACGTAACCGGGATTGCGATGCGGCATTGGCGGGCGGC
GTTTCTATCGAGATGCCTGCGTACCGGGGCTATGAATATCATGAAGGCATGATCAATGCGCGAGATGGTGTCTGTCGTCC
TTTCGATAGCCAAGCCTCTGGCACAGTCACCGGTGATGGCTTAGGAATGCTGCTGCTAAAACGTCTGGACGACGCGCTGG
CGGATCGGGACTGCATCTATGGTGTGATCAAAGGTTCGGCGGTCAATAATGATGGCAATAACAAAATCGGCTATACCGCG
CCGAGTGTGATCGGGCAATCAACGGTAATCCGCACCAGTTTGCGCCGTGCCGGTTTTGATAGCGACAGTATCGGATTGGT
GGAAGCGCACGGCACCGGTACGGTGCTGGGTGATCCTATTGAGTTACGTGCGCTTAATGAGGTGTTTGGCCCAACACCTG
TTCCGTTTTGTGTGGTTTCAGCGCTGAAAAGTAATATTGGCCACCTCAACTCCGCTGCGGGAGTGGCGGGCGTCATCAAA
ACAACGCTCGCCCTGCATCATCAAGTGTTGCCACCAACAGCGCACTTTCGCCAACTCAATCCTGCTATAGATCTATCGCG
TTCTGCATTGTACGTTAACCAGCAAGTCCAACCGTGGCCGTCGACGCGTCCTCGTCGTGCACTGGTGAGCTCCTTCGGCA
TCGGCGGCACCAATGCCAGCATCGCACTAGAAGCACATCAACATGAGGACGACCCTTCAGCGACGGGGGTACGCGACAGC
TATCTGTTGTTGTTCTCCGCTAAAACACCCGCTGCGTTAGAGTTGCGCGTGGCCTCCACACTGGAATATGTCAAGCATGG
AGTAGGGGTGCGCCTGCCGGATGTGGCTTATACATTGCAAACTGGACGCACAGCCTTTGACCATCGGCGGGCTTATTTGG
TGAGTCGTGGGTCGAAAATCGATCTCTCCTGTGCCACGATATTGCAAGCGGAAATCTTCAATGGTCAGCGCACGACAGCG
GAGATCTGCTTCATGTTTCCTGGTCAAGGTAGCCAATATCACGGCATGGCCAGCGCGCTCTATGCTCATCAACCCATGTT
TCGCCAGCACATGGATCGCTGCTTTGCTGCATTCCAACGCTATTCGACGGTCGATCTCAAGGCGTTGTTGTTTGACGATG
AGGATACGCGGGATATTGATCAAACGCAGTTCACACAACCGGCGTTGTTCTGTGTCGAATACAGCCTAGCGCGCACCTTG
ATTGATCTGGGGATTACGCCGGACAGTATGATCGGGCACAGTCTGGGCGAGTATGTTGCGGCCTGTATTGCTGGCGTATT
TACTCTTGAGGATGCGCTGCACGTCATTGAGGCGCGCGGACGTTTGATGCAGTCCATGCGTCCCGGTAGCATGATGGCGG
TCTACCTTAGTCGCGAACAGTTGACCCCATGGCTAGCTGCAGAACGGGGTATTGAACTGGCAGCTAATAATAGCGCGCAT
TTTTGCGTAGTCGCGGGCGAGCAGGCGGCCATTTCCCGTTTGAGCACACGCTTAGTCGAGGGCGGGATACAGCACAGGCG
CCTGAAAACCTCTCACGCATTCCACTCGGCCATGATGACGCCGATGCTGCACGATTTTGCACAGTTGCTGGGGCAAATCC
CGATGCACGCGCCGCACAAGCGCTTTATATCTAATGTAAGCGGTACATGGATTACTGAGGAGCAAGCTACCTCGCCGGAT
TACTGGGTGCAGCAAGTGCGCAACGCGGTGCTGTTTAGCGAAGGTGCGGCGCAACTGTTGGTACAACCCACGCTGTTTAT
CGAATGTGGGCCGGGTAATACGCTCTCTACCTTTATTCAAGGACATAACCAATACAGCGATCAGCCGACCCTGTTGACGC
TACGCAAAGCCAACGCGGCGATCGATGATGAGCACATGTTGCATCGTACGCTGGCGGCGCTGTGGGTCAGGGGGGAGAAT
ATTGATTGGAGACGCTTTAACCAGACGGCACTCGGCAAGCACATTCCATTGCCGGATTACCCCTTCGAACAGACTTATTA
CTATCGCTATGGTGCTGCACTTTCCGGTTATCGCCAGTATCCAAATCCTCTGCGCCGTCCGCAAGATGAGTGGCTCCAGC
GTGTGCTGTGGCGGATGCACGACACATCCTTGCGGGAGGCGTTCTATGCGCCGGGCGAATTGATCATCATTATTAGTGCT
GACGGCGACAAGTTACAGCAGACGCTGATGAGTAGTGGTGTCGACAGCATCACAATGCCGCTGCCGATATCGTCAGAGGA
CGACGTGTGGGATAATGACCGTATTCTGACGCATTTCCACGACATCTGCGCACTTTTAGCACACAAAACCTACCGACAGT
TACATTGCTTGTATGCTCCCGGTGCGGAGGCAGGATCATCGTTGACACAGTCGCTCTCGGGACTTTATCGTGTTGCTCGC
TGGTGTATGCACAGCACCACGCCGCTGGCGTCCTTAACAGTATTGACCCATGGTGCGTTTCGCGTACAGGAAGAGGATAA
TCCCGAACCGACGCTGGCAGCGTTGTCGGGCGCAGTAAACGTGTTTGCCCAAGAGCTGCACCCGACCGAAGTACGATTGA
TCGATATCGATGCGCAGAGCAGTGATGAGAATCTGAACTTGCTAACCCAGCGTCTGGCCCCGAAACAAGAAACGGTAATG
GCGCTCAGGCAGGGGATGCTTTACCTGCGACGCTTTATCCCGACACGGCTGTTGGCGCACTTACCCCCTCAAACAGGGTG
TATACCGGGCAACGTACTGTGGATTATCGGCGGTGAAAAGGGGATTGGCCGCATGATCGGCGAAGCGCTTGCTCAGCGTG
AGGGAGTCCGTGTGGTACTGAGCAGCCGCACAGGTTATCACCATGAAGCGGTGCAGCAGGACGCATTAGACGTTATCCAC
TGCGACGTGACGCAGGCGGAGGCGGTTAGAGCTTGTCTGGCAACTCTGCTCGAACGCTATGGACGGTTGGATGGCGTGAT
TTTTGCTGCCGACGCTACCACCACATTGACACTGCATCAATTGAGCGAATCTGCGCTACGCGACACGCTAACGGTGAAAG
AACGGGGTACTGCTAATGTGCTGCATGCGTTAGCGCAACGGAATCTGCTGGATGAGCGTCTGCTACTGCTGTTCTGTAAC
TCGTTGGCTGCCGTGAATGCGGAGATTGGCCAGACAGGCTATGCTACCGCCAGCGCCTATTTGGATGCACTGGCACAGCA
ACTGCGTACCCGCTACAAGGTGAATGCGCTCAGTATCGGGTTGGATGCATTGCGTGAGCAGGGCATGTTGTTGGATGCTA
TAAACGGCAGTGAATACGATGTCTTGCGTGGACTGCGCCCATTGATGACGGGAACGTTGCTACAGGCTTATAAACAACAA
GGGGCTGACACCAGCTACTACGCGCGATTATCCCCCGAGTCCGATTGGCTGCTGGATGAGCACCGGATATCCGGTATCGC
CACGCTGCCGGGAACCGGCTATCTGGCGCTGGCGTATGAAGCTCTGCGCCATTACTTTGTGCAAGACCAAATCTGCATTG
ATGAATTGGTCTTTTTGGCACCGTTGACTGTGATGGACAACTGCAGTGTTGACGTTTTTGTTGACATTTCACCTAACGGG
CAAGGAGTTAGTGTCGAGGTGAAATCAATGACGGAGCGCTTTAGTGGCACGTTAACAACCCATGCCAGAGGCAGGGCGAC
GCGTCTGATGGTAGACGATAATGTTGTGTGCGATCTCACGGGGCTGATGCGCGAGATGCACACTATCACTCCTCCAACAA
AGGAATTATCGAGCACGCACTTCCACTATGGGCCGCGCTGGCACAGCGTACAACAACTGTATGGCAATACCGCCCAGACT
CAGGTTTTCGCAACGCTGGCCCTGCCCACCGTTGCCGCTAATGATACGATCGCACTGCACCCTGCGCTGTTGGACATCGC
CAGCAGTGTTGTCGAACAACTGCCTGGTTTTCATACTGATTCGGTACCTTTCCTTTATCAGGATTTACGCCTGTACCGCC
CGTTGCCGAACACCTTACATGTGGCGCTGACTGTCAATCGGCACGATGAGGAGGGTGACAGCTACGCTTTCACGCTCTAC
GACATGGCAGGCGAGATGGTTGCCCGCTGTGCGGCAATGGTGAAGCGCAAGGTACAGCTCCACATACAAGATGTCGATGA
CGACACGCGACTGCGCGTGCCCAGTGCCGATAACTACCAACTGCGGCTGGCCGCTGAGGGGGAGGGGGCAGGAAAGCTAG
CGTTGTGCCCTACGCCGCGCTTAGCGCTGGGGGATTCACAAGTAGAGATTGAGGTACTGGCCACCGGACTGAACTTTAAG
GATGTGCTGTTCACCACGGGATTGCTCCGGCAGCAGCCGGGTGAGGCTCCGCTGCAATTGGGACTGGAGTGCGCCGGACG
CATTACTCGCGTGGGTAAAAATGTCACTGAATTTGCCCCGGGAGAGGATGTTATGGCGGTGCTAAACGGTGGTTTTGTCC
AGTACGCACGGGTAGAAAGCGATTGCGTAGTGAGAAAACCAGCCCATTGTCGCATCGAACAGGCGGCTGCGCTGCCTATC
GCATACCTCACCGCCTATTACGCACTGGTGGTGCGCGCTAATTTGCAACCCGGAGAACGAGTATTGATCCACAGTGCGGC
GGGGGGCGTTGGCTTGGCTGCGCTACATATTGCCAAACGCTGCGGAGCACAGATTTTCGCCACAGCAGGTAGCGAGCAGA
AACGCGATTACTTGCTTTCGCTAGGCGTACATGCCGTAGCTGATTCACACGACGAACAGTTCGCTGCCACTCTGCTGACC
GCATCGGACGGACAGGGGATGGATGTGATCCTTAACTCCCTCACAGGCCGTCTGCTTGACGCTAGCCTCGCGCTGCTGGC
ACCGCTGGGCCGTTTTCTTGAGCTGGGCAGCAAGGACATTGTGGAAGACAAAGCGCTACCGATGCGTTTCTTCGCCCAAG
GCGGCACCTTTATTCCGATTAATTTTCACGCGGCGCATGGTGCGTTTAGTCGCTACCTGCAACAGATTGTCGCTTGGATA
GATGATAACACGCTACCGCTCCTTCCATGCAAATCCGTACCATTGCCCGAGGTTGCACGCGCCTTCGCCACCCTGACCAC
GCCGCAGCATATTGGCAAGGTGGTGGTAACGCATCGCACTGCGGCAGGCATGGACCGGCTGAACGCCATGATAGCAGAAA
GGCGCCTCGGCGGCTATGCGCTCAGCATGAGCAATGCCGAGGTGATGCGCCAATTGTGGCCGATACTGAACACTCGCAGT
CCGTGGGCGCAACTGCTGCTCTCACCTCGGGCGATCGATAGATTAGCGCGGGGCAACCGGGTGGATCGCGGTGTACCGTC
TGCCGCTAACGATACGATTACTCAGCAGACAGTGAAAAAGCGGCCCCGTCCGGAAATTGGCGTGCCTTACAGCCCCGCGA
CACGTGAAGTGGAACGCGTGCTCTGCCAAATCCTGGAAGAGTATCTGGGTCTGGATAGAGTAGGCATTGACGACAACTAT
GCCGAATTAGGGGCAACCTCACTCGATATGGTGCAACTGAGTGGGCAAATGGCGCGTCACTATCCGCAAGTGAGCGTGGT
GTCGCTGTACAACCACGCCACCGTGCGCCAGCTGGCGACGTTTTGCCAGCCCCCGGAGGGCGAGTCAAATGCGCCATCAC
CACAGCCTGCAGTACAGACGAATACGCGCGCGAATCAGATAGCAAAACGTGCTTTGCAAATTGCGAAAAATACTGCGCGC
AGTCACACGTCTTTGCATTAA
>clbR|locus_tag=ECOK1_RS11410|product="colibactin biosynthesis LuxR family transcriptional regulator ClbR"|protein_id=WP_000357141.1
ATGGATAAGTTCAAAGAAAAAAACCCGTTATCTCTGCGTGAAAGACAAGTATTGCGCATGCTGGCACAAGGTGATGAGTA
CTCTCAAATATCACATAATCTTAACATATCAATAAACACAGTAAAGTTTCATGTGAAAAACATCAAACATAAAATACAAG
CTCGGAATACGAATCACGCTATACACATTGCTAACAGGAATGAGATTATCTAA
>clbA|locus_tag=ECOK1_RS11415|product="colibactin biosynthesis phosphopantetheinyl transferase ClbA"|protein_id=WP_001217110.1
ATGAGGATTGATATATTAATTGGACATACTAGTTTTTTTCATCAAACCAGTAGAGATAACTTCCTTCACTATCTCAATGA
GGAAGAAATAAAACGCTATGATCAGTTTCATTTTGTGAGTGATAAAGAACTCTATATTTTAAGCCGTATCCTGCTCAAAA
CAGCACTAAAAAGATATCAACCTGATGTCTCATTACAATCATGGCAATTTAGTACGTGCAAATATGGCAAACCATTTATA
GTTTTTCCTCAGTTGGCAAAAAAGATTTTTTTTAACCTTTCCCATACTATAGATACAGTAGCCGTTGCTATTAGTTCTCA
CTGCGAGCTTGGTGTCGATATTGAACAAATAAGAGATTTAGACAACTCTTATCTGAATATCAGTCAGCATTTTTTTACTC
CACAGGAAGCTACTAACATAGTTTCACTTCCTCGTTATGAAGGTCAATTACTTTTTTGGAAAATGTGGACGCTCAAAGAA
GCTTACATCAAATATCGAGGTAAAGGCCTATCTTTAGGACTGGATTGTATTGAATTTCATTTAACAAATAAAAAACTAAC
TTCAAAATATAGAGGTTCACCTGTTTATTTCTCTCAATGGAAAATATGTAACTCATTTCTCGCATTAGCCTCTCCACTCA
TCACCCCTAAAATAACTATTGAGCTATTTCCTATGCAGTCCCAACTTTATCACCACGACTATCAGCTAATTCATTCGTCA
AATGGGCAGAATTGA
>clbS-like_4ce09a
ATGAGTGTGCCGCAAACAAAAGCTGAACTGCTTTTAGCTATTGATAAAAATTTTAGTAAA
TTAATTAGTTACCTCAACACAATCCCACCAGAAATTACTTCAGATAAATCAATGGACGGA
CACGCCAAAGGAACGGAGATGAGTGTTCGTGATCTCGTTTCGTATCTGCTTGGATGGAAT
GCTCTTGTTGTAAAGTGGATCGCTTCTGATGCTAAAGGTCTGCCTGTCGATTTTCCGGAA
ACTGGCTATAAATGGAATCAGCTTGGCCTTCTTGCTCAAAAATTTTACTCAGATTACAGT
GAGTTAAGTTATGAGTTGTTAGTAGCTGAACTTCAGACTGTAAAAAATGAGATTGTGAAC
CTTATTAATGATCGTACCGATGATATTTTGTATGGAAGACCATGGTACACAAAATGGACG
ATGGGGAGAATGATCTCATTTAACACATCTTCGCCTTACGCCAACGCTAATGGAAGATTA
AGAAAGTGGGCAAAAAATAATAATATCAGTTTAAAGTAA