# Awesome Fruit Fly [![Awesome](https://awesome.re/badge.svg)](https://awesome.re)

> Interactive demos, games, trading loops, art, and dopamine / RL experiments that run a reconstructed *Drosophila* (fruit fly) connectome — especially **MaleCNS v1.0** (Sep 2026) and **FlyWire**.

The September 2026 MaleCNS release (~166,700 neurons spanning brain, optic lobes, and ventral nerve cord) set off a wave of community “fly brain” simulations: Doom, Mario 64, Beat Saber, Minecraft, BTC trading, browser pets, and closed-loop locomotion. This list is a curated index of those **applications**, not a catalogue of every dataset or analysis library.

For datasets, viewers, and analysis tools see the companion list **[awesome-fruit-fly-connectome](https://github.com/watthem/awesome-fruit-fly-connectome)**. We still keep a short [Datasets & tools](#datasets--tools) section so demos have context. Raw search notes from the Sep 2026 shards live in [`discoveries/`](discoveries/).

**These are wiring-diagram simulations.** Published connectomes give who connects to whom. Sensory maps, leaky-integrate-and-fire dynamics, dopamine pulses, and button bindings are almost always engineered. A listed project is not a living fly, and “learning” in a README is not proof of biological memory unless the authors publish controls that hold up.

Items whose point is a reward loop are collected under [Reinforcement & dopamine](#reinforcement--dopamine). Elsewhere, **Dopamine/RL** in the description means the same thing: identified PAM / PPL cells, a mushroom-body three-factor rule, or a trained readout / PPO policy on connectome topology.

Contributions welcome — see [CONTRIBUTING.md](CONTRIBUTING.md).

## Contents

- [Reinforcement & dopamine](#reinforcement--dopamine)
- [Games & interactive](#games--interactive)
- [Trading & markets](#trading--markets)
- [Art & media](#art--media)
- [Embodied / scientific RL](#embodied--scientific-rl)
- [Datasets & tools](#datasets--tools)
- [Related lists](#related-lists)
- [Articles & threads](#articles--threads)
- [Contributing](#contributing)
- [License](#license)

## Reinforcement & dopamine

Experiments that inject reward or aversion into identified dopamine cells (PAM11 appetitive, PPL101 aversive, mushroom-body three-factor rules) or treat the connectome as a plastic RL substrate.

- [20fly8](https://github.com/dtecx/20fly8) - **Dopamine/RL.** FlyWire mushroom body (5,177 Kenyon cells, 62,261 plastic KC→MBON synapses) learns 2048 in the browser. Tile merges are sugar; PAM / PPL1 are the only teacher. After 3,000 games the published fly scores 6,986; rewiring the nose drops it to 925 and shuffling the learned synapses to 1,287. The reward-prediction error is computed outside the circuit. [ [play](https://dtecx.github.io/20fly8/) ]
- [ChessFly](https://github.com/znatgost/chessfly) - **Dopamine/RL.** FlyWire mushroom body (5,177 Kenyon cells) teaches itself chess in the browser. Real wiring learns about as well as the same cells with shuffled inputs; look-ahead is engine code, not a fly. [ [play](https://znatgost.github.io/chessfly/) ]
- [DOOMFLY](https://github.com/nftechie/doomfly) - MaleCNS v1.0 (166,700 neurons) plays a live Doom arena; frames drive R1–R6 / R8 inputs, damage pulses two PPL101 cells, and an experimental rule updates KC→MBON11 synapses. Announced by [@nftechie_](https://x.com/nftechie_) on 6 Sep 2026. Open source; the repo is explicit that learned survival has not been demonstrated. [ [live spectator](https://fly-brain-doom.awormuth.chatgpt.site/) ]
- [Faiku](https://github.com/xyzzyapps/faiku) - MaleCNS mushroom-body RL writes Japanese/English haiku as a fly-font ink trail, with PAM / PPL1 dopamine on glyph match.
- [Fly / Wirehead](https://github.com/mattyhempstead/fly-wirehead) - Endless insect Shorts on a phone in front of the same retained MaleCNS graph. Every accepted frame injects current into 15 PAM11 cells — artificial “wirehead” dopamine, inspired by Stonkfly. Preference and addiction are not established.
- [fly-brain-poker](https://github.com/ItayParienty/fly-brain-poker) - FlyWire mushroom-body LIF sat at Texas Hold’em. Innate wiring can discriminate hands; outcome-driven dopamine did **not** teach cards. Honest negative result.
- [fly-mario](https://github.com/ksanjeev284/fly-mario) - Full MaleCNS v1.0 playing NES Super Mario Bros with CUDA LIF dynamics, dopaminergic learning, and a live 3D web dashboard.
- [Fly School](https://github.com/JaronKBragg7337/fly-school) - MaleCNS mushroom-body depression (PAM / PPL1 onto KC→MBON) drilled on Morse timing during “school hours.” Held-out `.-` barely moves; `-.` stays 0 — an honest mostly-null. [ [live](https://www.heartbeatobservatory.com/school/) ]
- [FlySoul](https://github.com/heyobi/flysoul) - MaleCNS LIF vs Iudex Gundyr in SoulsGym. Damage pulses PPL101 (LTD); a boss hit pulses PAM (LTP). The biological loop wins once in ~600 fights and does not learn to; a synthetic readout on the same senses wins about one in three. [ [write-up](https://heyobi.github.io/flysoul/) ]
- [FlyScroll](https://github.com/ranagwho/Fruitfly-Doomscroller) - MaleCNS “doomscroller”: short-form video into R1–R8; the feed advances when novelty-compartment KC→MBON synapses habituate. Habituation / prediction-error, not a PAM11 profit pulse.
- [FlyTris](https://github.com/rothilion26/flytris) - MaleCNS mushroom body (KC→MBON, PAM / PPL1) learns Tetris as odor-gradient navigation with the fly’s own dopamine-gated plasticity rule.
- [flywire-playground](https://github.com/hills-dong/flywire-playground) - FlyWire sub-circuits as spiking networks that play games using the fly’s own dopamine update rule.
- [Fruit fly utopia](https://github.com/ML-Chen/fruit-fly-utopia) - MaleCNS soma cloud plus a reduced PAM / PPL1 / PER rate model. Worlds include sugar, cocaine, doomscroll, and a printed “utopia” welfare mix that is **not** “max PAM”; cocaine loses. Wanting / reinforcement, not a trained policy.
- [Kick the Fly](https://github.com/legendarylolo318-cloud/kick-the-fly) - Kick-the-buddy toy on a live 166,700-neuron MaleCNS. Tools hit real sensory cells; sugar lights PAM dopamine and heals. Reward is the sugar pulse, not a trained game policy.
- [Pokefly](https://github.com/Reldnahc/pokefly) - Pixel-driven Pokémon Red (PyBoy) on MaleCNS via fly.ai: fixed spatial adapter, internal synaptic plasticity kept across whole-game attempts, and a live neural dashboard. Reaching the battle is part of the task. Distinct from `blackicon-eth/fly-plays-games` (frozen weights).
- [PoopFly](https://github.com/Chawakorn111/PoopyFly) - MaleCNS core (165,650 neurons that have an edge) decides when to defecate. Homeostatic improvement is a dopamine-like three-factor rule on real synapses. Gait and the toilet are code; the assumptions note says what is not claimed. Local app.
- [Ruby Project](https://github.com/wavendis/ruby-project) - NeoForge Minecraft 1.21.1 mod that gives a mob a FlyWire-derived LIF brain (photoreceptors, descending neurons, Kenyon cells, MBON, DAN) with dopamine-gated KC→MBON learning. Real wiring plus a few synthetic Minecraft entry neurons; the author documents what is fabricated.
- [Scrollfly](https://github.com/sebastian-stapf/scrollfly) - MaleCNS watches Shorts, predicts watch time, “likes,” and scrolls. Frozen graph + trained readout; does not beat a constant baseline. Credits Stonkfly and Fly / Wirehead. [ [demo](https://sebastian-stapf.github.io/scrollfly/) ]
- [Stonkfly](https://github.com/nftechie/stonkfly) - BTC-USDC candlestick pixels into MaleCNS; a fixed readout proposes buy / sell / hold via Coinbase AgentKit. Portfolio gains pulse 15 PAM11 cells, losses pulse two PPL101 cells. Profitable learning has not been demonstrated. X: [@nftechie_](https://x.com/nftechie_/status/2098012107652391357). [ [stonkfly.com](https://stonkfly.com) · [live dashboard](https://stonkfly-three.vercel.app/) ]
- [StonkFlyRH](https://github.com/CryptoGatsu/StonkFlyRH) - Stonkfly fork on Robinhood Chain memecoins. Gains → 15 PAM11, losses → 2 PPL101; a rug it bought doubles the aversive pulse. Advertised X: [@StonkFlyRH](https://x.com/StonkFlyRH).
- [stonkfly-lab](https://github.com/paappraiser/stonkfly-lab) - Smaller mushroom-body trading lab with odor inputs, delayed dopamine, two-fly agreement, paper BTC, and a dashboard. Inspired by Stonkfly; not the full MaleCNS graph.
- [The Fly’s Table](https://github.com/WilliamJones/fly-blackjack) - Heads-up blackjack against a measured MaleCNS mushroom body (682 PN, 1,200 KC, 97 MBON, 332 PAM / PPL1). 30k solo hands move winrate from −45% to −16% with 52% basic-strategy agreement; cutting dopamine wipes the gain. Circuit subset. [ [play](https://fly-blackjack.vercel.app/) ]

## Games & interactive

Connectome activity mapped onto game controls or a playable / inspectable agent. Prefer repos and live pages; X-only clips are marked.

- [Aimbug](https://github.com/slickdomi/aimbug) - Browser FPS: full MaleCNS steers via DNa02 / DNp53 and fires one shot per pIP10 courtship-song bout while LC10 “sight” is open. No trained readout. [ [play](https://aimbug.domi.zip/) ]
- [alpha-fly](https://github.com/turlockmike/alpha-fly) - **RL.** Full MaleCNS (166,700 neurons, 10.5M connections) taught chess by self-play: one gain per synapse, signs and partners frozen. A same-degree, same-sign shuffle is in the training log; the README says the wiring is probably not special for chess. The published curve beats Stockfish only while Stockfish plays mostly random moves. [ [play](https://turlockmike.github.io/alpha-fly/) ]
- [Beat Saber (Lyra)](https://x.com/_lyraaaa_/status/2097527368919470162) - **X-only.** [@\_lyraaaa\_](https://x.com/_lyraaaa_) (“the fly brain can play beat saber,” 8 Sep 2026). Author notes motor patterns were overfit to a replay with teacher-forced input while visual reactivity / RL training continued — not fully reactive play from pixels alone.
- [Banana Quest](https://github.com/professorwang/flybrain-banana-quest) - Browser foraging on FlyWire FAFB v783 (139,255 LIF), with an optional MaleCNS mode that includes the ventral nerve cord (Zenodo: 176,422 neurons). Odor and motor maps are artificial. A technical note shows that a glutamate-sign packaging flip is synaptic-mass balance, not glutamate itself. [ [play](https://professorwang.github.io/flybrain-banana-quest/) · [Zenodo](https://doi.org/10.5281/zenodo.22998484) ]
- [Beat the Fly](https://github.com/saintiron82/beat-the-fly) - Jigsaw race vs a 7,858-cell MaleCNS photoreceptor→L1 graph in one tab. Shuffle-wiring solves as well; the fly visual system is a motion system, not a jigsaw solver. [ [play](https://saintiron82.github.io/beat-the-fly/) ]
- [Brain Rot](https://github.com/Franz23/brainrot) - FlyWire v783 rates a LinkedIn post: engagement bait → sugar GRN Hz → Shiu whole-brain lookup → MN9 verdict. The inspectable “write LinkedIn posts” 404 Media named without a URL. [ [rate](https://brainrotposts.com) ]
- [CyberFly](https://github.com/PtPavloTkachenko/fly-brain-spectacles) - Hologram flies on Snap Spectacles; each runs full MaleCNS on a Mac Metal GPU while the glasses stream room senses. [ [blog](https://pavlo-stijn.dev/blog/posts/a-real-fly-brain-on-spectacles.html) ]
- [DesktopFly](https://github.com/DenisSergeevitch/desktop-fly) - 3D fly on a macOS / Electron desktop. FlyWire looming / escape plus a MaleCNS motor extract; cursor looming can trigger Giant Fiber takeoff.
- [FlyCNS Desktop Pet](https://github.com/Teafox113/FlyCNS-Desktop-Pet) - Windows always-on-top 2D pet: 3,335 R1–R6 plus an engineering-cruise vs “pure BCI” control. MaleCNS-derived; neuromod / sugar telemetry are optional and documented as unverified.
- [Flyguy](https://github.com/Cem-Bas/flyguy) - macOS Tamagotchi: ScreenCaptureKit vision through 165,122 / 10.5M MaleCNS plus a live soma cloud. Gentle hue/app affinities, not a PAM11 loop. Distinct from DesktopFly.
- [Flytown](https://github.com/KapilSareen/flytown) - Browser town whose citizens each run an 8,000-neuron MaleCNS prune (234,363 connections). Sugar→feed and looming→escape are the reflexes the README says emerge; café, brawl, and home goals are a hand-made layer. Nothing is trained. [ [play](https://kapilsareen.github.io/flytown/) ]
- [Fly Terrarium](https://github.com/jonathancomergit-ai/fly-terrarium) - Local GPU LIF of 165,122 / 23.8M MaleCNS in a tank: sugar, bitter, fan, courtship song, and a swat, plus a flyvis webcam optic-lobe page. Honesty table (cartoon body vs real wiring); lab bench can silence the giant fiber. No public host.
- [Fly64 / Super Mario 64](https://github.com/ornata/fly) - Jessica Paquette ([@barrelshifter](https://x.com/barrelshifter)) hooks MaleCNS to a decompiled SM64 build: six hidden cameras, LIF dynamics, DNg100 / DNa02 / DNp01 readouts. No training or reward in the published loop; Mario can walk into a wall and stay there. [ [announcement](https://x.com/barrelshifter/status/2097004115826200898) ]
- [Fly Brain (Boxhead)](https://github.com/FalinX/fly-brain) - Frozen MaleCNS (166,700 / 25.6M) plays Boxhead-style zombie survival. v13 kiter-legs + connectome eyes: ~197 s median survival vs a no-brain kiter ~216 s (statistically level). Local Python; no public host.
- [Fly Brain Minecraft](https://github.com/blendi-remade/fly-brain-minecraft) - Fabric 1.21.1 mod: each fly mob runs a MaleCNS LIF brain with a live HUD. Distinct from NeuroCraft (runnable mod vs landing page) and from [Ruby Project](https://github.com/wavendis/ruby-project) (FlyWire + dopamine).
- [MaleCNS Bee](https://github.com/Pacsy1/MaleCNSBee) - Paper Minecraft plugin: a bee runs MaleCNS (165,733 traced or anchor neurons). The author is explicit that this is a fly nervous system in a bee body, with no trained motivation. Local server.
- [Fly-chan](https://github.com/fkfkfk0406/fly-chan) - FlyWire v783 (138,639 LIF) as a 3D tamagotchi girl / anatomical fly. Relationship gauges are authored; DNs/MNs pick feed / startle / groom. ~100 MB first load. [ [play](https://fkfkfk0406.github.io/fly-chan/) ]
- [FlyBreak](https://github.com/Shriya-sai/FlyBreak) - 30-second neural heist: cut or jam MaleCNS nodes so LC4 cannot reach DNg108 while sparing protected DNa13. The fly reroutes every four seconds. [ [play](https://flybreak-neural-heist.shriyasai8.chatgpt.site) ]
- [fly_chess](https://github.com/martialsystems/fly_chess) - Chess via a connectome LIF ply plus search. The README reports that one LIF ply on the real graph is silent and `wiring_helped` is false — an honest negative result.
- [fly-chess (WASM)](https://github.com/tolatolatop/fly-chess) - Separate FlyWire LIF chess experiment in the browser (Rust / WASM) with spike traces and causal controls. [ [demo](https://tolatolatop.github.io/fly-chess/) ]
- [Doodle Fly](https://github.com/dtecx/doodle-fly) - Whole FlyWire v783 (138,639 LIF, no training) plays a Doodle-Jump-style game. Intact runs fall 0–1 times in two minutes (scores around 12,500); swapped eyes fall 41–44 times; a blind fly hops in place. Target→LC10a drive is hand-made. [ [play](https://dtecx.github.io/doodle-fly/) ]
- [Fly Dino](https://github.com/cobanov/flyjump) - **RL readout.** Chromium Dino jumped by an 80-cell MaleCNS circuit plus a CEM-trained 243-parameter readout (99/100 held-out courses in the published checkpoint). Wiring is frozen. [ [play](https://flydino.cobanov.dev/) ]
- [Fly Falafel King](https://github.com/Eli-HarShefer/fly-brain-falafel) - FlyWire subgraph (4,798 LIF / 116,960 synapses) plays an original Falafel King: LC10a→AOTU→DNa02 locks onto trays; LPLC2→DNp01 slaps flies off the food. Order-reading is authored game logic; the fly does not learn. Circuit subset. [ [play](https://eli-harshefer.github.io/fly-brain-falafel/) ]
- [Flybrain FPV](https://github.com/slickdomi/flybrain-fpv) - Full MaleCNS (166,700 neurons) flies an FPV strike drone in the browser on WebGPU, by the Aimbug author. Yaw is DNa02, climb is DNp53, escape is DNp01. Truck painting, lock, dive assist, and forest turn-away are game code; with no target drive the published hit rate collapses. [ [play](https://flybrain-fpv.domi.zip) ]
- [FlyDrones](https://github.com/SpikeCalls/FlyDrones) - Webcam / keyboard optic-flow illusions (open palm climb, fist hold, rush-the-camera giant-fiber escape) steer a 3D drone via DNg02 / DNp01. Browser demo is MiniFly (~850 cells) plus a safety governor, not the full 166k graph. [ [play](https://spikecalls.github.io/FlyDrones/) ]
- [Fly Marksman](https://github.com/webergithub/fruitfly-lab) - 3,963-neuron FlyWire LC10a→AOTU→DNa02 pursuit circuit aims in the browser with no training. Same circuit on ViZDoom *defend_the_center*: real wiring 10.2 kills/episode vs a degree-preserving scramble 0.7. Bearing→LC10a drive is engineered. [ [play](https://opcstudio.cc/fly-aim/) ]
- [Fly-NAF](https://github.com/ArtyMend07/Fly-NAF) - Whole FlyWire v783 (138,639 LIF, frozen weights) plays Five Nights at Freddy's 1. DNp01 slams doors; DNp09 raises the tablet; camera-up blinds the fly via GABAergic inhibitors. Best published run: 4 AM on night 2. Windows only.
- [Subject 783](https://github.com/RootVandal/subject-783) - Whole FlyWire (138,639 Shiu LIF neurons) in a browser horror lab. Blocking a neuron makes it permanently unexcitable; loud sound into Johnston’s organ can fire the giant fiber. [ [play](https://rootvandal.github.io/subject-783/) ]
- [fly-swing](https://github.com/JHC56/fly-swing) - MuJoCo fly web-swings a random obstacle course. Escape is LC4/LPLC2 → DNp01 Giant Fiber (no dodge code); the full 165,122-neuron graph is a live HUD. A kNN threat memory picks web direction (20/20 published courses).
- [Fly Tic-Tac-Toe](https://github.com/pikabell/fly-tictactoe) - **RL readout.** 98-cell MaleCNS circuit + a 425-parameter readout in the browser, with silence / rewire controls. Imitation of minimax uses the circuit; a degree-preserving rewired graph scores about the same — topology is not the skill. [ [play](https://pikabell.github.io/fly-tictactoe/) ]
- [fly-escape](https://github.com/dzhng/fly-escape) - 3D browser house-escape: place furniture, release flies whose MaleCNS LIF circuits drive movement. [ [play](https://fly-escape.vercel.app/) ]
- [fly-explorer](https://github.com/brandoncho369/fly-explorer) - FlyWire (~139k neurons) as a live browser spiking network. Press sugar, watch a proboscis motor neuron fire. Companion benchmark: [flybench](#datasets--tools). [ [demo](https://www.fly-bench.com) ]
- [flywire-fly-lab](https://github.com/suifei/flywire-fly-lab) - FlyWire v783 (138,639 / 15.1M) on a 16 GB laptop with **17,628** virtual knockouts; the browser game is 4,599 cells. κ 0.59 sugar / 0.87 water / 0.91 grooming vs opto. [ [play](https://suifei.github.io/flywire-fly-lab/game.html) ]
- [MaleCNS Asteroids](https://github.com/dohun1214/malecns-asteroids) - Full 166,700-neuron LIF plays Atari Asteroids. Escape (LC4→DNp02/11) vs pursuit (LC10a→DNa02) readouts; silencing two DNp11 cells flips steering while a random 2,000-cell lesion does not. Local CUDA; no public host.
- [fly-flappy-bird](https://github.com/arjunkshah12345-hash/fly-flappy-bird) - MaleCNS wired to Flappy Bird with engineered adapters and recorded gameplay.
- [Hand-loom Giant Fiber](https://github.com/Euraxluo/fly-brain-drone) - Browser 5,145-neuron MaleCNS LPLC2/LC4→DNp01 looming loop: drag toward the fly; slow hands miss the spike and swat it. Not the full 166k graph. Distinct from already-listed [Swat](https://github.com/hrook1/Swat) (LC16→MDN) and from `abbosaliboev/fly-brain-drone` (MuJoCo apple-finding WIP). [ [play](https://euraxluo.github.io/fly-brain-drone/) ]
- [fly-hero](https://github.com/actuallyrizzn/fly-hero) - Frozen fly-connectome reservoir that plays Clone Hero by seeing the highway.
- [fly-mania](https://github.com/Shirtep/fly-mania) - **RL readout.** Frozen 3,418-neuron / 242,111-synapse MaleCNS subgraph plus a 352,971-parameter DAgger controller plays osu!mania 4K. No reward signal; the teacher exists only during training. Local.
- [Fly Poker](https://github.com/HappyAny/fly-poker) - Two-player 13-card shedding game vs a full-connectome fly sim in the browser. [ [play](https://fly-poker.piphipsi.com/) ]
- [fly-brain-bench](https://github.com/RaphaelSR/fly-brain-bench) - Browser LIF over FlyWire (138,639 neurons, ~2.7M connections) at 60 fps with no extra dependencies.
- [FlyBrain (boss)](https://github.com/Jhongdlp/FlyBrain) - Video-game boss driven by MaleCNS (~165k neurons): Rust engine, vectorized Python VecEnv, Three.js visualizer. Not a DRL policy.
- [FlyBrain-HalfLife](https://github.com/Yusuftmle/FlyBrain-HalfLife) - MaleCNS / FlyWire agent playing Half-Life via LIF dynamics, a 60×60 retina, and DirectInput.
- [flybrain.app](https://flybrain.app) - Browser FlyWire FAFB v783 simulation (139,255 LIF neurons) forked from worm-sim. [ [repo](https://github.com/snedea/flybrain) ]
- [flybrain-intransitive](https://github.com/charbelkassab/flybrain-intransitive) - Full MaleCNS LIF plays rock-paper-scissors chess with no training: captures as small-object chase, threats as looming / giant-fiber escape. Scrambled wiring collapses; a learned descending readout played *worse* than the biological approach/escape pair. Feature→neuron map is still hand-designed.
- [flybrain-snake](https://github.com/charbelkassab/flybrain-snake) - Live MaleCNS (~165k neurons) playing Snake, with the control mapping documented instead of hidden.
- [flydoom](https://github.com/mutkuoz/flydoom) - Alternate Doom fly on Princeton’s FAFB-v783 (FlyWire) dataset rather than MaleCNS.
- [FLYBRAIN-BAD_APPLE_X_DOOM](https://github.com/fazchile17/FLYBRAIN-BAD_APPLE_X_DOOM) - Local 3D FlyWire v783 viewer (139,255 neurons) with optional Bad Apple!! and Doom overlays on the neurons.
- [flyputer](https://github.com/migkapa/flyputer) - Local Gemma agent queries FlyWire, runs small LIF subcircuits, and includes a playable Giant Fiber swatter game against the real LPLC2/LC4 escape reflex.
- [Fruit Fly Plays Fruit Ninja](https://github.com/hcsolakoglu/fruit-fly-plays-fruit-ninja) - 4,386-neuron MaleCNS visuo-motor circuit slices fruit via a fitted descending readout. Local 3D “fly at a PC” spectator plus measured / rewired / cut / blinded controls. Not whole-brain; connectome weights stay frozen.
- [Fruit Fly Simulation (Xenova)](https://huggingface.co/spaces/Xenova/fruit-fly-simulation) - Joshua Lochner’s WebGPU MaleCNS demo: paint / stimulate 166,700 neurons and watch an articulated Three.js fly. Connectivity is biological; movements are programmed. Verified Hugging Face Space (not a GitHub repo).
- [NANDFLY](https://github.com/wetware-labs/nandfly) - Giant Fiber escape compiled to 661 NAND/LATCH gates on BNB Chain. The site lets you swat the netlist; 98.9% jump agreement vs a LIF reference on all 4,096 input patterns. Top-12 of 311 LC4/LPLC2 cells, not the full fan-in. [ [swat](https://wetware-labs.github.io/nandfly/) ]
- [Model Kombat](https://github.com/lavallee/mk-jev-fly-brain) - 12,000-neuron MaleCNS subgraph (LPLC2/LC4/LC10a/P1 → DNp09/MDN/TTMn) fights a language model in mk.js. A dopamine-like rule updates during the fight; controls say what each side contributes. Not whole-CNS. [ [play](https://lavallee.github.io/mk-jev-fly-brain/) ]
- [NeuroCraft Fly](https://github.com/evnsnclr/neurocraft-fly-public) - Evan Sinclair Smith’s Minecraft MaleCNS fly (166,700 neurons). In-game events (food, light, nearby creatures, attacks) drive the network; activity selects scripted body programs. Public landing page and recorded demo; the Fabric mod itself was still being prepared as of the Sep 2026 landing-page README.
- [Optic-lobe steering](https://github.com/AbijahKaj/fruit-fly-brain-research) - MaleCNS optic lobe (65.8k neurons) as a WebGPU rate model: the fly renders 1,771 column directions and the wiring becomes wing commands. [ [browser demo](https://fruit-fly-research.vercel.app/) ]
- [PersonConnectome](https://github.com/TailsProwerWorks/PersonConnectome) - People Playground Human driven by a thresholded MaleCNS-derived LIF graph. Game senses (injury, looming, audio, liquids as telemetry) map to a frozen decoder; it does not learn from staying alive.
- [Ragdoll playground](https://github.com/kenprosi/PFPG---fruit-fly-playground) - Browser People Playground–style sandbox: up to two people can wear all 139,255 FlyWire neurons. Leg motion, fear, and hunger are rules; the README’s mushroom-body path weakens KC→MBON synapses when PAM or PPL1 fires. No public host (`Play.bat`). Distinct from PersonConnectome (MaleCNS, frozen decoder).
- [pianist-fly](https://github.com/Noir-infini/pianist-fly) - Full MaleCNS LIF (166,700 / 25.58M) hunts a sugar plume over a piano and strikes keys with Damped Least Squares IK on a MuJoCo body. Frozen graph; local only.
- [Same Smell](https://github.com/anzal1/samesmell) - One cVA puff into MaleCNS (he) and FlyWire (she) at once: he lunges, she pauses. Extra modes play Pong between the two brains and let both courtship circuits swipe dating profiles. LIF timing is stretched; bodies are puppets on real descending output. [ [play](https://anzal1.github.io/samesmell/) ]
- [Swat](https://github.com/hrook1/Swat) - Browser arcade: swat a fly whose evasive turns are influenced by a 6,000-neuron MaleCNS LC16→MDN retreat circuit. [ [play](https://fruitfly-tiny-brain.vercel.app/) ]

### X-only or thinly documented game clips

- [Bad Apple!!](https://github.com/kevinlinxc/badapple-fly) - Kevin Lin ([@linguinelabs](https://x.com/linguinelabs) in news write-ups) pipes Bad Apple!! through MaleCNS v1.0 and shows a NeuroMechFly body. Open-source; LIF parameters and movement programs are illustrative. Coverage also used the X handle; the repo is the verified source.
- [Deadlock](https://knowyourmeme.com/videos/440448-fruit-fly-brain-simulations) - **X-only.** [@jetsetworm](https://x.com/jetsetworm) (11 Sep 2026): “the fly can play deadlock” with YOLOv5 + video pretraining, “most success on Graves.” No numeric status ID archived here; no public repo. YOLO is a vision front-end, not a fly retina.
- [Fly social network](https://x.com/nftechie_/status/2098371978612924425) - [@nftechie_](https://x.com/nftechie_) (13 Sep 2026): three male and three female connectomes with separate states; presenting flies stimulates sensory neurons and activity decides whether another fly responds (“TheFlybook”). No public repo was found at write-up.
- [Mario 64 follow-ups](https://x.com/barrelshifter) - After the [7 Sep 2026 clip](https://x.com/barrelshifter/status/2097004115826200898), [@barrelshifter](https://x.com/barrelshifter) posted further SM64 training experiments (including a “teaching to Kill” follow-up circulated in community notes). Those later clips were not independently archived with a verified status ID here.
- [Parallel parking](https://x.com/alright_mark/status/2098085928489177142) - **X-only.** [@alright_mark](https://x.com/alright_mark) (10 Sep 2026): “the fly has completed* the ultimate test: parallel parking.” Status ID from public unroll/news embeds. No first-party repo tied to this handle; not the same as [Flyhard](https://github.com/MarkUnthank/flyhard).
- [Super Smash Bros / Rubik’s cube](https://x.com/nickwalton00/status/2098537903110652087) - **X-only.** [@nickwalton00](https://x.com/nickwalton00) (13 Sep 2026): Smash “wins against the bots 2/3 matches” and a [Rubik’s](https://x.com/nickwalton00/status/2098301053372621070) follow-up. Status IDs from unrollnow. No public repo; not the same as [lntegrals/flycube-public](https://github.com/lntegrals/flycube-public). Methods not inspectable.

## Trading & markets

Same caveat as the dopamine section: a chart-in / trade-out loop is an interface, not a proven alpha. **Dopamine/RL** tags mark PAM / PPL pulses or KC→MBON updates.

- [The Dartboard](https://flybrain.online/dartboard) - **Dopamine/RL.** fruitflydev 165,122-neuron MaleCNS walks a dark room of nine identical stock cards (smell = ticker; DNp09 ≥ 200 Hz while slow commits). Paper only — no GitHub in the 22 Sep clip. Live page: learning ±0.04 vs look noise, **no claimed edge**; Fly vs Random vs Hold. Does not name PAM11 / PPL101. X: [@fruitflydev](https://x.com/fruitflydev/status/2102092842537734496).
- [the_buzz](https://github.com/TropiFloAI/the_buzz) - Bitcoin prediction bake-off: random forest vs a fruit-fly-connectome network.
- [flycoinrh](https://github.com/fruitflydev/flycoinrh) - MaleCNS-scale connectome (165,122 neurons) used to launch tokens on Robinhood Chain. Meme-token experiment; treat as entertainment, not a model organism. X: [@fruitflydev](https://x.com/fruitflydev/status/2100964182028099993) (Flyonardo airdrop, 18 Sep) · [stock-room trader](https://x.com/fruitflydev/status/2101298482002927874) (19 Sep).
- [flybrain-female](https://github.com/opifor/flybrain-female) - FlyWire FAFB v783 “sister” token experiment on Robinhood Chain. Launch-form / cursor demo; no P&L dopamine loop in this README. [ [site](https://femaleflybrain.com) ]
- [flywire-live](https://github.com/iyz2013/flywire-live) - Robinhood Chain *spectator*: other people’s swaps become sensory current in a MaleCNS LIF. The fly never signs a tx. Advertised site `flywire.live` failed TLS / 404 at re-check; use the repo.
- [fruit-fly-fund](https://github.com/armanbabazadeh6/fruit-fly-fund) - Two MaleCNS v1.0 flies race the same paper market; one applies experimental memory updates and one does not. No real orders. [ [demo](https://armanbabazadeh6.github.io/fruit-fly-fund/) ]
- [fruitfly.trade](https://github.com/fruitflytrader/fruitfly.trade) - Simulated connectome whose spikes choose memecoin trades. [ [site](https://fruitfly.trade) ]
- [FlyTV](https://www.tradingview.com/script/nmnHkA02-FlyTV-a-real-fruit-fly-connectome-trading-on-your-chart/) - **Dopamine/RL.** TradingView Pine: 995-neuron MaleCNS distillation. Looming (LC4 / LPLC2 → DNp01) flattens a selloff; realized P&L drives PAM / PPL1 onto KC→MBON. Includes a shuffled-weight control. Does not beat buy-and-hold after fees.
- [Gregor](https://github.com/PunzRH/gregor) - “A real fruit-fly connectome kept alive by its coin.” Separate from Richy.
- [FlyDegen](https://flydegen.fun/docs) - **Offline.** FlyWire FAFB v783 LIF that maps tape to sugar / bitter / antennal rates (MN9 = BUY). Docs say no RL / P&L fine-tune. Host returned HTTP 402 (`DEPLOYMENT_DISABLED`) at re-check; no public GitHub found.
- [OpenFly](https://github.com/marketcalls/openfly) - **Dopamine/RL (learning arm).** MaleCNS v1.0 paper-trades an intraday NIFTY straddle through OpenAlgo. Default path is a fitted decoder; the learning arm pulses 15 PAM11 / 2 PPL101. No profitable edge claimed.
- [Polyfly](https://polyfly.higgsfield.app/) - Live neural trader on one Polymarket Fed-funds contract. MaleCNS-scale model; marked P&L becomes “reward or aversive stimulation.” Does not name PAM11 / PPL101. No public GitHub found.
- [Richy The Fly](https://github.com/PunzRH/richythefly) - **Dopamine/RL.** Full MaleCNS v1.0 trades Pons coins on Robinhood Chain from its own wallet; Δequity pulses 15 PAM11 or 2 PPL101. Advertised site returned 404 at re-check; repo + [@RichyTheFly](https://x.com/RichyTheFly) remain the pointers. Profitable learning not claimed.
- [Stonkfly](https://github.com/nftechie/stonkfly) - See [Reinforcement & dopamine](#reinforcement--dopamine). The canonical dopamine-gated trading demo.
- [StonkFlyRH](https://github.com/CryptoGatsu/StonkFlyRH) - See [Reinforcement & dopamine](#reinforcement--dopamine). Robinhood Chain fork.
- [TraderFly](https://github.com/SotoAlt/traderfly-brain) - Male CNS LIF maps sugar GRNs → BUY, looming LC4 / LPLC2 → ESCAPE sell. No PAM11 / PPL101 P&L pulse. [ [live](https://traderfly.xyz) ]

## Art & media

- [9 to Fly](https://github.com/MarlonSteiner/fruitfly-9tofly) - 809-neuron DNp01 Giant Fiber slice at a sales desk: the phone rings, the fly leaves the chair. Looming vs receding vs flat inputs are 1.00× — selectivity is upstream of this slice. Movement is keyframed. [ [demo](https://marlonsteiner.github.io/fruitfly-9tofly/) ]
- [BioReservoir](https://github.com/igdigitallab/bioreservoir) - Fixed MaleCNS reservoir (165,122 LIF neurons) answers yes/no questions. Text embeddings become sensory Poisson rates; an untrained MN9-versus-DNp01 contrast is the readout. On the pre-registered midterm batch the real brain’s mean p(yes) is 0.5001 (range 0.4930–0.5053) across 33 questions; outcomes are not scored yet. Controls: no-brain, degree-preserving rewire, Erdős–Rényi, seeded coin. Created 22 Sep 2026 and missed by that day’s hunt. [ [ask](https://fly.igdigi.com) ]
- [DJ Drosophila](https://github.com/MRsagi/dj-drosophila) - MaleCNS-inspired fly DJ and shared 24/7 CC0 live radio.
- [Drosophila-Lang](https://github.com/UniversidadCamiloJoseCela/drosophila-lang) - Esoteric language on FlyWire v783 (138,639 neurons, 2,700,513 connections with at least five synapses). Each step is a real neuron; each variable is a KC→MBON synapse that PAM / PPL1 strengthen or weaken; the program ends when the giant fiber fires. Local.
- [The Drosophila Critic](https://github.com/Synthetic-Humanities-Lab/drosophila-critic) - Spoken Blake *The Fly* into Johnston’s organ cells on a frozen MaleCNS; the published reading never sees the poem text. [ [Blake edition](https://synthetic-humanities-lab.github.io/drosophila-critic/) ]
- [Faiku](https://github.com/xyzzyapps/faiku) - See [Reinforcement & dopamine](#reinforcement--dopamine). Haiku as a dopamine-gated ink trail.
- [Fly Applicant](https://github.com/Jeremiah-Sakuda/fly-applicant) - Full MaleCNS (166,700 neurons, 25.6M connections, Fly64-style LIF) applies to scripted jobs in a 3D office. The market, the rejection copy, and the single interview are authored. [ [live](https://fly-office.vercel.app) ]
- [FLM](https://github.com/nftechie/flm) - **Trained readout, not dopamine.** Frozen Liquid AI 1.2B LM whose logits are nudged by a 278k-parameter adapter on the full retained MaleCNS graph. Language comes from the backbone; a no-graph control does slightly better. [ [chat](https://fly-language-model.vercel.app/) · [paper](https://artificialscientific.com/papers/flies-are-all-you-need) ]
- [Fly Lab](https://github.com/Apolotary/fly-lab) - **RL readout.** Ableton Live: fly motor-circuit activity → a small trainable musical “More / Less like this” readout. Wiring frozen.
- [Fly OCR](https://github.com/jerryjliu/fly_ocr) - Frozen MaleCNS as a printed-character reservoir; a 266k-parameter decoder scores 87.6% on a 1,632-glyph benchmark and 5.7% CER on selected PDF lines. A 3° tilt breaks it. Local replay viewer; not a claim that flies read.
- [The Fly Hears](https://github.com/rahilmavani/fly-hears) - Spoken digits through a 30k-cell MaleCNS auditory slice; a logistic reader scores 70.0% vs scrambled wiring 69.7%. Local demo; wiring frozen.
- [FLYcasso](https://github.com/gustavz/FLYcasso) - Connectome-conditioned image diffusion and simulated fly painting on MaleCNS wiring.
- [Grey Leno](https://github.com/SpikeCalls/grey-leno-fly-brain) - Whole FlyWire (138,639 LIF neurons, 15.1M connections) puppets a late-night host. Tomatoes, applause, and sugar stimulate identified sensory cells; descending neurons move the body. A PAM / PPL1 term is in the published loop. Fan project. [ [show](https://flyleno.viosarcade.xyz/) · [poke](https://spikecalls.github.io/grey-leno-fly-brain/) ]
- [flyboard](https://github.com/sukoji/flyboard) - Music chart voted by a GPU simulation of MaleCNS v1.0 (~165k neurons) after 84 songs. [ [viewer](https://sukoji.github.io/flyboard/) ]
- [Fruitflysynth](https://github.com/bennjordan/fruitflysynth) - In-browser MANC thoracic courtship circuit plus physical-model DSP: drag the female closer and pulse song becomes sine song. Not MaleCNS whole-CNS. [ [play](https://bennjordan.github.io/fruitflysynth/) ]
- [Fruit fly utopia](https://github.com/ML-Chen/fruit-fly-utopia) - See [Reinforcement & dopamine](#reinforcement--dopamine). Sugar / cocaine / doomscroll / utopia as motor programs on a PAM–PPL1 cartoon.
- [FLYWATT](https://github.com/flywatt-live/watt-the-fly) - Browser MaleCNS subset (38,178 neurons, 5.1M synapses); every spike is converted to power and lights a bulb (~6.5 µW).
- [Infinite Sugar](https://github.com/cnqso/infinite-sugar) - Browser FlyWire terrarium with continuous sweet-GRN stimulation — a wirehead / “pleasant life” metaphor. No learning, so it cannot get bored. Displayed PAM rates are telemetry, not a trading reward. [ [demo](https://infinitesugar.cnqso.com) ]
- [Муха смотрит телевизор](https://github.com/georgesher/fly24-public) - Full MaleCNS LIF (Stonkfly C++ kernel) watches live IPTV and changes channels from Kenyon-cell / Giant Fiber telemetry. Pixels only; “boredom” is an authored label. Local FastAPI; created 22 Sep 2026.
- [Music in the Body](https://github.com/matsuo-koya/music-in-the-body) - Endless browser instrument on a ≥5-synapse MaleCNS graph (163,997 bodies) in a Web Worker. Harmony and timbre mapping are authored; includes a rewired comparison. [ [instrument](https://matsuo-koya.github.io/music-in-the-body/) ]
- [swat-or-buy](https://github.com/oskarmalmwiklund/swat-or-buy) - Ad creatives scored by a MaleCNS retina/lamina running in the browser. You pick first; the fly “BUYs” glance salience and swats the rest. Deep `buy`/`swat` cells are silent under LIF (graded optic lobe); the live show uses honest glance/boredom. [ [play](https://swat-or-buy.vercel.app/) ]
- [Xenova fruit-fly-simulation](https://huggingface.co/spaces/Xenova/fruit-fly-simulation) - See [Games & interactive](#games--interactive). The cleanest in-browser MaleCNS canvas.

## Embodied / scientific RL

Closed-loop bodies, locomotion policies, and research-grade simulators. Several predate the Sep 2026 meme wave and are included because later demos stand on them.

- [Antennal grooming](https://github.com/NeLy-EPFL/antennal-grooming) - Connectome-derived grooming network plus kinematic replay in a MuJoCo / FARMS fly body (Özdil et al., *Nature Communications* 2026). [ [DOI](https://doi.org/10.1038/s41467-026-72152-x) ]
- [BioDrone_RL](https://github.com/Kartha-33/BioDrone_RL) - PPO drone in a 3D obstacle course with a fly-inspired compound-eye sensor and sparse / small-world policy. Inspired by Drosophila motion circuits; a “real connectome data” phase was still planned in the Mar 2026 README.
- [boltzmann-fly](https://github.com/jniimi/boltzmann-fly) - Purchase-World Deep Boltzmann Machine whose couplings are masked to right-hemisphere MaleCNS PN→KC→MBON. Visit AUC matches the dense original; a free-energy clamp test **flips sign** vs a degree-preserving rewire. Magnitudes are learned; the mask is the wiring.
- [Drosophila_brain_model](https://github.com/philshiu/Drosophila_brain_model) - Shiu et al. whole-brain FlyWire LIF model (*Nature* 2024). The sensorimotor reference most MaleCNS game kernels cite.
- [flyconnectome-nulls](https://github.com/gyujeongion/flyconnectome-nulls) - Compressed FlyWire v783 agents evolve next to randomised wiring. Standard shuffles beat the connectome because they invent olfactory→motor shortcuts the compressed graph lacks; boundary-preserving nulls wipe the gap. Pre-registered; one registered prediction failed and is reported as failed. [ [Zenodo](https://doi.org/10.5281/zenodo.22871090) ]
- [eonsystemspbc/fly-brain](https://github.com/eonsystemspbc/fly-brain) - Eon Systems whole-brain FlyWire v783 LIF emulation across Brian2, PyTorch, NEST GPU, and GeNN backends.
- [erojasoficial-byte/fly-brain](https://github.com/erojasoficial-byte/fly-brain) - FlyWire v783 (138,639 neurons) in a NeuroMechFly v2 / MuJoCo body with vision, olfaction, flight, and Hebbian plasticity. [ [pages](https://erojasoficial-byte.github.io/fly-brain/) ]
- [fly.ai / flybrain](https://github.com/alextitonis/fly.ai) - Runnable MaleCNS v1.0 spiking network on CPU (Numba) or GPU (CuPy), with a neuron model following [Fly64](https://github.com/ornata/fly). [ [PyPI](https://pypi.org/project/flybrain/) ]
- [fly-afterlife](https://github.com/nsfm/fly-afterlife) - Whole MaleCNS LIF with a flyvis optic-lobe seam on true compound-eye geometry, plus a FlyWire female sharing a room. Timestamped `docs/SEAM.md` lab notebook; local only.
- [fly-brain-zero-shot](https://github.com/vib2810/fly-brain-zero-shot) - FlyWire whole-brain LIF plus flyvis eyes steers a NeuroMechFly body toward poles and keeps going after two legs are cut. Intact about 2.96 poles per 10 s versus scrambled wiring about 0.34. The leg rhythm is a hand-built pattern generator; two gains were tuned, neither on injured flies. Local.
- [fly-cartpole](https://github.com/Curt-Park/fly-cartpole) - 5,459-neuron MaleCNS flight-stabilisation circuit balances CartPole. Untuned wiring already lasts 275.6 of 500 steps (the cart leaves the track; the pole does not fall); five self-tuned sensor gains hit the cap. Synapses stay frozen. An earlier mushroom-body dopamine attempt averaged 392.5 steps. [ [viewer](https://curt-park.github.io/fly-cartpole/) ]
- [fly-cord-robots](https://github.com/SakshayMahna/fly-cord-robots) - MANC / MaleCNS ventral nerve cord as a walking CPG on a simulated hexapod, then an “amputated” quadruped. Spinal-cord I/O, not a whole-brain game kernel.
- [fly-garden](https://github.com/hama-jp/fly-garden) - **RL readout.** Full MaleCNS LIF (166,700 / 25.6M) sees a Three.js garden; a Double DQN layer picks seven locomotor actions. Connectome weights stay frozen.
- [Fly-Brain-AI / plastic-fly](https://github.com/neilt93/Fly-Brain-AI) - Closed-loop FlyWire (139k LIF neurons in Brian2) + FlyGym / MuJoCo. The `plastic-fly/` package is the brain–body bridge, ablation / odor / looming experiments, and analysis — not a separate GitHub repo.
- [fly-brain (browser WASM)](https://github.com/Lulzx/fly-brain) - Embodied whole-CNS MaleCNS LIF in the browser (WASM) plus MuJoCo flybody and flyvis vision.
- [flybody](https://github.com/TuragaLab/flybody) - Anatomically detailed MuJoCo whole-body fly (DeepMind + Janelia). Controllers are MLPs, not connectome graphs — this is the body FlyGM later wraps. Vaxenburg et al., *Nature* 2025. [ [DOI](https://doi.org/10.1038/s41586-025-09029-4) ]
- [flybrain-play](https://github.com/victory-c/flybrain-play) - **RL readout.** Whole MaleCNS LIF tastes drinks and balances a road bike. Literature walking-command neurons mostly stay silent and do not track the lean; flight-steering descending neurons do. A 71-parameter decoder fitted to a PD teacher keeps 16 riders up for a mean of 14.1 s out of 15 s. The connectome weights stay frozen. [ [live](https://flybrain-play.vercel.app) ]
- [fly-fpv](https://github.com/joey-david/fly-fpv) - **RL.** MaleCNS adjacency-masked sparse controller trained (behavior cloning, then PPO) to fly a 3D hoop course. Weights learned; topology constrained.
- [Flybrain (gate course)](https://github.com/YYK2007/flybrain) - **RL readout.** Full 166,700 / 25.6M *rate* model on a 3D gate course; a logistic decoder on 64 population averages flaps. Trained 6/6 held-out courses; silenced 0; **presynaptic shuffle also 3/3** — the README does not claim topology is the skill. Distinct from [fly.ai / flybrain](https://github.com/alextitonis/fly.ai) (LIF runtime). Local `127.0.0.1:8765`.
- [Flyhard](https://github.com/MarkUnthank/flyhard) - **RL.** MaleCNS model learns to turn a physical steering wheel with fly legs and drive CARLA (stock Mini Cooper). Documented hold-out steering.
- [Haltere Pilot](https://github.com/Ameerkhanjk/haltere-pilot) - Simulated quadrotor whose gyro enters **haltere afferents** and whose motors are real wing MNs. Tuned gains reach 93% of a teacher; silencing 204 haltere cells crashes every second, while 204 random cells do almost nothing.
- [therealfly](https://github.com/fruitflydev/therealfly) - Full MaleCNS LIF (165,122 / 10.2M) coupled to flybody with **no written controller**. Preregistered stage 1 (DNa01+DNa02 cord rhythm) **FAIL**: left–right anti-phase 0/3; a degree-preserving scramble makes the same 11 Hz peak. Stages 2–3 not run on that evidence. Offline science; no wallet.
- [fly-self-driving](https://github.com/suanmiao/fly-self-driving) - MaleCNS-scale connectome (165k neurons, 25.6M synapses) trained to drive a simulated street from pixels. [ [demo](https://fly-self-driving.kylon.app) ]
- [flyverse](https://github.com/djmango/flyverse) - Native Rust MaleCNS v1.0 sim embodied in a virtual room, with a browser visualizer. See also [flyverse-core](https://github.com/tel-0s/flyverse-core) (transmitter-aware core).
- [FLYNN](https://github.com/ben-gitdev/fly-gym) - **RL / imitation.** FlyWire FAFB v783 as a ~139k-unit sparse RNN trained with DAgger to drive a wheeled MuJoCo robot, vs small-world and CNN baselines. Wang & Chen, arXiv:2607.00025.
- [Fly Space Program](https://github.com/steph4n-gh/fly-space-program) - **RL readout.** Full retained MaleCNS plus a learned ten-command readout flies a simulated booster (60/80 unseen landings in the published release; covering the eyes → 0/80). Orbital missions and the physical “Fly Cube” are not demonstrated. [ [sim](https://fly.steph4n.dev/) ]
- [Fruitless](https://github.com/nicodunks/fruitless) - MaleCNS mAL-block courtship assay with a recorded-activity Three.js fly. Male-cue responses rise after the block; female cues still win — increased responsiveness, not male preference.
- [FlyGM](https://arxiv.org/abs/2602.17997) - Jin, Zhu, Zhang, Sui. *Whole-Brain Connectomic Graph Model Enables Whole-Body Locomotion Control in Fruit Fly*. Instantiates the adult whole-brain connectome as a directed message-passing graph and trains it with RL (imitation + PPO) on flybody for walking, turning, and flight. [ [project](https://lnsgroup.cc/research/FlyGM) · [site](https://sites.google.com/view/flygm) ]
- [FlyGym / NeuroMechFly v2](https://github.com/NeLy-EPFL/flygym) - Physics digital twin of adult *Drosophila* (vision, olfaction, terrain, SAC obstacle-avoid). The body most embodied demos attach a connectome to. Wang-Chen et al., *Nature Methods* 2024. [ [DOI](https://doi.org/10.1038/s41592-024-02497-y) · [NeuroMechFly v1](https://github.com/NeLy-EPFL/NeuroMechFly) · [docs](https://neuromechfly.org/) ]
- [flyvis](https://github.com/TuragaLab/flyvis) - Connectome-constrained deep mechanistic model of the fly visual system in PyTorch (Lappalainen et al., *Nature* 2024). The visual prior reused by NeuroMechFly v2 fly-following. [ [DOI](https://doi.org/10.1038/s41586-024-07939-3) · [docs](https://turagalab.github.io/flyvis/) ]
- [Descending-neuron atlas](https://github.com/shreyansatvik/fly-brain-to-body-drosophila-descending-neurons) - Interactive map of 481 MaleCNS descending-neuron types onto the body parts they excite or inhibit.
- [VNC walking CPG](https://github.com/smpuglie/Pugliese_2026) - Pugliese et al. firing-rate VNC simulations that identify a walking CPG (DNg100 / DNb08 screens). [ [bioRxiv](https://doi.org/10.1101/2025.09.12.675944) ]
- [Walking in the wiring](https://github.com/kosmoKwan/fly-connectome-wiring) - Fixed-weight rate models of the adult leg motor system from MaleCNS v1.0 and MANC, each compared with six families of rewired networks. Code for Guan, Zhao, Zhang, Lyu, and Chen, *How much of fly walking is written in the wiring?* (2026).
- [Virtual Embodied Fly](https://github.com/TheFlyExperiment/Virtual-Embodied-Fly) - Documentation landing page for a closed-loop FlyWire + NeuroMechFly “virtual embodied fly” announcement (Eon Systems / Shiu lineage). Marketing-heavy README; runnable code lives in [eonsystemspbc/fly-brain](https://github.com/eonsystemspbc/fly-brain).
- [virtual-fly-lab](https://github.com/Leon-Av/virtual-fly-lab) - Full-CNS MaleCNS fly living in a Godot 4 sandbox.

## Datasets & tools

Short orientation only. Deeper coverage lives on [watthem/awesome-fruit-fly-connectome](https://github.com/watthem/awesome-fruit-fly-connectome).

- [MaleCNS v1.0](https://male-cns.janelia.org/) - Complete adult male CNS (brain + optic lobes + VNC, intact neck connective): ~166,700 neurons, ~125 million synapses. FlyEM / Janelia, Cambridge, MRC LMB, and Google Research. Data **CC BY 4.0**. Primary paper: Berg, Beckett, et al., *Sexual dimorphism in the complete Drosophila male central nervous system connectome*, [*Cell* (3 Sep 2026)](https://doi.org/10.1016/j.cell.2026.08.015). [ [Google Research blog](https://research.google/blog/a-connectomics-milestone-mapping-the-complete-male-fruit-fly-brain/) · [downloads](https://male-cns.janelia.org/download/) · [neuPrint](https://neuprint.janelia.org) · [Cell Type Explorer](https://reiserlab.github.io/celltype-explorer-drosophila-male-cns/) ]
- [FlyWire / FAFB](https://flywire.ai) - Complete adult female brain (~139,255 neurons, ~50 million synapses), 2024. Data **CC BY-NC 4.0**. Primary paper: Dorkenwald et al., *Neuronal wiring diagram of an adult brain*, [*Nature*](https://doi.org/10.1038/s41586-024-07558-y). Companion atlas: Schlegel et al., [*Nature*](https://doi.org/10.1038/s41586-024-07686-5). [ [Codex](https://codex.flywire.ai) ]
- [BANC](https://github.com/htem/BANC-project) - Brain And Nerve Cord, female whole-CNS. Bates, Phelps, Kim, Yang et al., *Nature* (2026). [ [DOI](https://doi.org/10.1038/s41586-026-10735-w) · [bioRxiv](https://doi.org/10.1101/2025.07.31.667571) ]
- [MANC](https://doi.org/10.7554/eLife.97769) - Male Adult Nerve Cord. Takemura et al., *eLife* (2024).
- [malecns (natverse)](https://github.com/natverse/malecns) - R access to `male-cns:v1.0` via neuPrint.
- [flybench](https://github.com/brandoncho369/flybench) - 36 pre-registered reflex tasks on FlyWire v783 and MaleCNS (shuffled-wiring controls, flyvis eye, FlyGym body). Working gain ~0.45, not published 1.0; spike-frequency adaptation beats the reference LIF. Companion to [fly-explorer](#games--interactive). [ [leaderboard](https://www.fly-bench.com/bench) ]
- [flybrain SDK](https://github.com/freeman-1984-coder/flybrain-sdk) - CPU LIF runtime, game APIs, and on-demand MaleCNS / FlyWire data (no CUDA required).
- [connectome-host](https://github.com/anima-research/connectome-host) - **Not biology.** Anima Research’s recipe-driven agent host (web UI / TUI / headless fleet) on their “Connectome” software stack (agent-framework, context-manager, chronicle, membrane). Name collision with MaleCNS / FlyWire wiring diagrams; no *Drosophila* graph.
- [connectome-kernels](https://github.com/QuixiAI/connectome-kernels) - Fused CUDA kernels for training a recurrent net on a fixed sparse graph (built for FlyGPT / MaleCNS Shakespeare). Tooling, not a demo.

## Related lists

- [awesome-fruit-fly-connectome](https://github.com/watthem/awesome-fruit-fly-connectome) - Datasets, papers, viewers, analysis libraries, and a shorter viral-experiments section. Complementary: they curate the science stack; this list curates demos and dopamine / RL use cases.
- [awesome-fly](https://github.com/cobanov/awesome-fly) - Parallel community index (games, desktop flies, language/art, research tools) by the Fly Dino author, with a [fly-connectome-template](https://github.com/cobanov/fly-connectome-template) starter. Overlaps this list; last content push 30 Sep 2026 (Banana Quest, BioReservoir, and Fly Self Driving, which was already listed here). Useful as a second pass.
- [`discoveries/`](discoveries/) - Uncurated search shards (games / media / art, science / embodied RL, trading / dopamine / wirehead, the 14–22 Sep 2026 and 2 Oct 2026 X/web and GitHub cool-hunts, and a 25 Sep 2026 name-collision note for [anima-research/connectome-host](https://github.com/anima-research/connectome-host)). Stronger items are folded into the sections above; the shards keep rejected and “mentioned, not verified” notes.

## Articles & threads

Verified reporting and primary posts. Tweet IDs appear only when an archive or news embed confirmed them.

- [A connectomics milestone: Mapping the complete male fruit fly brain](https://research.google/blog/a-connectomics-milestone-mapping-the-complete-male-fruit-fly-brain/) - Google Research, 3 Sep 2026.
- [Scientists mapped a fruit fly’s brain. The internet made it play Doom](https://www.ibm.com/think/news/fruit-fly-connectome-brain-map-minecraft-doom) - IBM, 22 Sep 2026 recap (Minecraft, Doom, Beat Saber, parallel parking, Stonkfly, kebab, LinkedIn). No new first-party repos beyond what this list already tracked.
- [Sexual dimorphism in the complete Drosophila male central nervous system connectome](https://doi.org/10.1016/j.cell.2026.08.015) - Berg, Beckett, Costa, Schlegel, Januszewski, Marin, et al., *Cell* 189(18), 3 Sep 2026. [ [bioRxiv](https://www.biorxiv.org/content/10.1101/2025.10.09.680999) ]
- [Neuronal wiring diagram of an adult brain](https://doi.org/10.1038/s41586-024-07558-y) - Dorkenwald et al. / FlyWire Consortium, *Nature*, 2024.
- [A Drosophila computational brain model reveals sensorimotor processing](https://doi.org/10.1038/s41586-024-07763-9) - Shiu et al., *Nature*, 2024. The LIF kernel many demos copy.
- [Whole-body physics simulation of fruit fly locomotion](https://doi.org/10.1038/s41586-025-09029-4) - Vaxenburg et al., *Nature* 2025 (flybody).
- [Connectome-constrained networks predict neural activity across the fly visual system](https://doi.org/10.1038/s41586-024-07939-3) - Lappalainen et al., *Nature* 2024 (flyvis).
- [Whole-Brain Connectomic Graph Model Enables Whole-Body Locomotion Control in Fruit Fly](https://arxiv.org/abs/2602.17997) - FlyGM, arXiv:2602.17997.
- [FLYNN: Robust Neural Network for Robot Navigation using Fly Brain Topology](https://arxiv.org/abs/2607.00025) - Wang & Chen, arXiv:2607.00025.
- [@nftechie_ — Doom training](https://x.com/nftechie_/status/2097711063135383642) - “the fly brain can play doom” (6 Sep 2026). Frames → sensory neurons; damage → two PPL101 cells. Status ID from unrollnow.
- [@nftechie_ — Stonkfly](https://x.com/nftechie_/status/2098012107652391357) - “I gave the fly brain $100 to trade bitcoin.”
- [@nftechie_ — fly social network](https://x.com/nftechie_/status/2098371978612924425) - Three male + three female connectomes.
- [@fruitflydev — Flyonardo airdrop](https://x.com/fruitflydev/status/2100964182028099993) - 18 Sep 2026. NFT canvases claimed by burning $FLYBRAIN. Status ID from unrollnow. Repo: [flyonardo-da-vinci](https://github.com/fruitflydev/flyonardo-da-vinci) (already in the 17 Sep shard; token wrapper).
- [@fruitflydev — stock-room trader](https://x.com/fruitflydev/status/2101298482002927874) - 19 Sep 2026. “gave the fly $10,000 to trade stocks.” Live paper build is [The Dartboard](#trading--markets); that page is more conservative than the tweet (no edge claimed).
- [@fruitflydev — dartboard clip](https://x.com/fruitflydev/status/2102092842537734496) - Clip-only; no GitHub in the post. [flybrain.online/dartboard](https://flybrain.online/dartboard) (200).
- [Flies Are All You Need](https://artificialscientific.com/papers/flies-are-all-you-need) - FLM methods note: full retained MaleCNS reservoir on a frozen 1.2B LM. Direct-input control slightly beats the fly graph. Conversational recipe is [nftechie/flm](https://github.com/nftechie/flm); study artifacts stay private.
- [@barrelshifter — Mario 64](https://x.com/barrelshifter/status/2097004115826200898) - “playing mario 64 using a fly's brain.”
- [@_lyraaaa_ — Beat Saber](https://x.com/_lyraaaa_/status/2097527368919470162) - “the fly brain can play beat saber.”
- [@alright_mark — parallel parking](https://x.com/alright_mark/status/2098085928489177142) - “the fly has completed* the ultimate test: parallel parking.”
- [@nickwalton00 — Smash / Rubik’s](https://x.com/nickwalton00/status/2098537903110652087) - Super Smash Bros clip; [Rubik’s](https://x.com/nickwalton00/status/2098301053372621070). X-only; no public repo found.
- [404 Media](https://www.404media.co/a-digital-fly-brain-has-taken-over-the-internet/) - 15 Sep 2026 recap (Minecraft, Doom, Beat Saber, Stonkfly, parking). Names kebab / LinkedIn / “bi fly” without first-party URLs for those.
- [Inquirer / NYT — “Is there anything a fruit fly brain can't do?”](https://www.inquirer.com/news/nation-world/fruit-fly-brain-map-simulation-video-games-parking-dancing-research-20260917.html) - 17 Sep 2026 recap (Rubik’s, YMCA four-tone dance, poker/blackjack, kebab). Names Unthank blinkers on Flyhard; no first-party URLs for YMCA / kebab. Blackjack now has [The Fly’s Table](#reinforcement--dopamine).
- [SuperTruth — Intelligence Is Structure, Not Scale](https://supertruth.ai/research/connectome) - Frozen MaleCNS (166,700 / 6.24M ≥5-synapse edges) trained to copy a health-record trust index vs LLM baselines. Pre-registered reservoir experiment, not a clinician. [ [paper](https://doi.org/10.5281/zenodo.22865214) · [repo](https://github.com/evil-robot/supertruth-connectome-public) ]
- [Quantum Zeitgeist — Fly OCR](https://quantumzeitgeist.com/fruit-fly-ocr/) - 14 Sep 2026 write-up of jerryjliu/fly_ocr.
- [Gizmodo](https://gizmodo.com/google-mapped-a-fruit-flys-brain-now-its-playing-doom-and-super-mario-64-2000808616) - Doom + Mario 64 recap with embedded posts.
- [TechSpot](https://www.techspot.com/news/113780-google-mapped-fly-nervous-system-developers-using-play.html) - Confirms the barrelshifter status URL and the PPL101 Doom loop.
- [PC Gamer](https://www.pcgamer.com/hardware/after-google-mapped-an-adult-male-fruit-flys-brain-software-engineers-made-it-play-doom-mario64-and-beat-saber/) - Doom, Mario 64, and Beat Saber wave.
- [Know Your Meme — Fly Brain Simulations](https://knowyourmeme.com/memes/fly-brain-simulations-fruit-fly-brain-mapped) - Spread timeline (Beat Saber, Stonkfly, parallel-parking clips). Treat as a meme log, not a methods paper.

## Contributing

New demo? Open a PR. The bar is a working link, a one-line factual description, and honesty about what is simulated. Details in [CONTRIBUTING.md](CONTRIBUTING.md).

## License

List text is [CC0 1.0](LICENSE) (public domain dedication), the usual license for awesome lists.

Linked projects and datasets keep their own terms. **MaleCNS data is CC BY 4.0** (attribution required; commercial use allowed). **FlyWire / FAFB data is CC BY-NC 4.0** (non-commercial). Check each source before you ship a fork.

*Last updated 2 October 2026, during the MaleCNS demo wave. Fly on. 🪰*