--- title: Optimization Introduction subtitle: Biostat/Biomath M257 author: Dr. Hua Zhou @ UCLA date: today format: html: theme: cosmo embed-resources: true number-sections: true toc: true toc-depth: 4 toc-location: left code-fold: false jupyter: jupytext: formats: 'ipynb,qmd' text_representation: extension: .qmd format_name: quarto format_version: '1.0' jupytext_version: 1.14.5 kernelspec: display_name: Julia (8 threads) 1.8.5 language: julia name: julia-_8-threads_-1.8 --- # Introduction * Optimization considers the problem $$ \begin{eqnarray*} \text{minimize } f(\mathbf{x}) \\ \text{subject to constraints on } \mathbf{x} \end{eqnarray*} $$ * Possible confusion: * We (statisticians) talk about **maximization**: $\max \, L(\mathbf{\theta})$. * People talk about **minimization** in the field of optimization: $\min \, f(\mathbf{x})$. * **Why** is optimization important in statistics? * Maximum likelihood estimation (MLE). * Maximum a posteriori (MAP) estimation in Bayesian framework. * Machine learning: minimize a loss + certain regularization. * ... * Our major **goal** (or learning objectives) is to * have a working knowledge of some commonly used optimization methods: * Newton type algorithms * quasi-Newton algorithm * expectation-maximization (EM) algorithm * majorization-minimization (MM) algorithm * convex programming with emphasis in statistical applications * implement some of them in homework * get to know some optimization tools in Julia * What's **not** covered in this course: * Optimality conditions * Convergence theory * Convex analysis * Modern algorithms for large scale problems (ADMM, CD, proximal gradient, stochastic gradient, ...) * Combinatorial optimization * Stochastic algorithms * Many others * You **must** take advantage of the great resources at UCLA. * Lieven Vandenberghe: EE236A (Linear Programming), **EE236B** (Convex Optimization), **EE236C** (Optimization Methods for Large-scale Systems). One of the best places to learn convex programming. * Kenneth Lange: Biomath 205 (Top Computational Algorithms). **The** best place to learn MM type algorithms.