params { result_dir = 'results/dia_batch_correction' // Where results will be saved report_dir = 'reports/dia_batch_correction' // Where nextflow reports will be saved panorama.reports_folder = null // A map of Skyline documents and metadata files // File paths can be local file paths or Panorama WebDav urls documents = ['<project_name>': ['skyline': '<path_to_skyline_doc>', 'metadata': '<path_to_metadata_tsv>'] ] // Normalization parameters normalize_db { // List of replicates to exclude from normalization and batch correction exclude_replicates = null // List of Skyline documents to exclude from normalization and batch correction exclude_projects = null // Normalization method to use. Options are 'DirectLFQ' and 'median' method = 'DirectLFQ' } // Batch correction parameters bc { // batch correction method method = 'combat' // Metadata keys corresponding to batch levels 1 and 2 // If null, the project name is used as the batch variable batch1 = null batch2 = null // Metadata key(s) used to color PCA plots. // Can be either string or list. If null, batch and acquisition number are used to color plots. color_vars = null // Metadata key(s) to use as covariates for batch correction // Can be either string or list. If null, no covariates are used. covariate_vars = null // Metadata key indicating replicates which are controls for CV plots // If null, all replicates are used in CV distribution plot. control_key = null // Metadata value(s) mapping to control_key indicating whether a replicate is a control. control_values = null // File extension for standalone plots. If null, no standalone plots are produced. plot_ext = 'pdf' } } // Execution Profiles profiles { standard { process.executor = 'local' executor.queueSize = 8 params.max_memory = '30.GB' params.max_cpus = 16 params.max_time = '24.h' } }