Protein synthesis is the ultimate step of gene expression and a key control point for regulation. In particular, it enables cells to rapidly manipulate protein production without new mRNA synthesis, processing, or export. This pathway gives an overview of the translation factors involved in this process. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP107 CPTAC Assay Portal]. d48 now E2K2 HUMAN TrEMBL accession number O43177 refers to same protein. Also contains 40S subunit and initiator tRNA.

11909525 PubMed Gene-specific regulation by general translation factors. Cell 2002 Dever TE translation pathway PW:0000101 Pathway Ontology