Estrogen receptor refers to a group of receptors which are activated by the hormone 17β-estradiol (estrogen). Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the estrogen G protein coupled receptor GPR30 (GPER), which is a G-protein coupled receptor. The main function of the estrogen receptor is as a DNA binding transcription factor which regulates gene expression. However the estrogen receptor also has additional functions independent of DNA binding. This pathway was inferred from Homo sapiens pathway [http://www.wikipathways.org/index.php?title=Pathway:WP712&oldid=29739 WP712(r29739)] with a 90% conversion rate. HDAC2; histone deacetylase 2 HDAC3; histone deacetylase 3 HDAC7A; histone deacetylase 7 HDAC6; histone deacetylase 6 HDAC1; histone deacetylase 1 HDAC5; histone deacetylase 5 HDAC8; histone deacetylase HDAC4; histone deacetylase 4 estrogen signaling pathway PW:0000507 Pathway Ontology