This pathway was inferred from Homo sapiens pathway [http://www.wikipathways.org/index.php?title=Pathway:WP697&oldid=30275 WP697(r30275)] with a 75% conversion rate. d4e e6e aa4 e4d e4f aef d2e e4d d2e d2e ae5 e4d e4f d2e e4d d2e e4d e4f e4d d2e e4f e4d d2e e4d e4d e4d e4d d2e d4e ae5 e4d d2e e4d d2e e4d ae5 d2e d2e d2e e4d ae5 steroid metabolic pathway PW:0001303 Pathway Ontology 10963623 PubMed Estrogen metabolism by conjugation. J Natl Cancer Inst Monogr 2000 Raftogianis R Creveling C Weinshilboum R Weisz J 12587805 PubMed 2-Methoxyestradiol, a promising anticancer agent. Pharmacotherapy 2003 Lakhani NJ Sarkar MA Venitz J Figg WD 12727798 PubMed Relative imbalances in estrogen metabolism and conjugation in breast tissue of women with carcinoma: potential biomarkers of susceptibility to cancer. Carcinogenesis 2003 Rogan EG Badawi AF Devanesan PD Meza JL Edney JA West WW Higginbotham SM Cavalieri EL 9380738 PubMed Molecular origin of cancer: catechol estrogen-3,4-quinones as endogenous tumor initiators. Proc Natl Acad Sci U S A 1997 Cavalieri EL Stack DE Devanesan PD Todorovic R Dwivedy I Higginbotham S Johansson SL Patil KD Gross ML Gooden JK Ramanathan R Cerny RL Rogan EG 16280036 PubMed Genetic polymorphisms in human SULT1A1 and UGT1A1 genes associate with breast tumor characteristics: a case-series study. Breast Cancer Res 2005 Shatalova EG Walther SE Favorova OO Rebbeck TR Blanchard RL 15607759 PubMed Estradiol metabolites as isoform-specific inhibitors of human glutathione S-transferases. Chem Biol Interact 2004 Abel EL Lyon RP Bammler TK Verlinde CL Lau SS Monks TJ Eaton DL 15535854 PubMed Metabolic inactivation of estrogens in breast tissue by UDP-glucuronosyltransferase enzymes: an overview. Breast Cancer Res 2004 Guillemette C Belanger A Lepine J 12714703 PubMed Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damage. Mol Endocrinol 2003 Bianco NR Perry G Smith MA Templeton DJ Montano MM