Pentose phosphate, phosphogluconate, or hexose monophsphate pathway oxidizes glucose-6-phosphate to fructose-6-phosphate and glyceraldehyde-3-P. NADP+ is the electron acceptor. The pathways yields NADPH as well as 5, 4, and 7 carbon intermediaries for synthesis of nucleotides. Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP134) cab pentose phosphate pathway PW:0000045 Pathway Ontology 10.1016/0307-4412(90)90145-E DOI Biochemistry 0307-4412(90)90145-E 1990 D. Voet J.G. Voet