Glycolysis is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO− + H+. The free energy released in this process is used to form the ATP and NADH. Gluconeogenesis is a metabolic pathway that results in the generation of glucose from non-carbohydrate carbon substrates such as pyruvate, lactate, glycerol, glucogenic amino acids, and fatty acids. Description adapted from [http://www.wikipedia.org Wikipedia]. This pathway was inferred from Homo sapiens pathway [http://www.wikipathways.org/index.php?title=Pathway:WP534&oldid=28564 WP534(r28564)] with a 76% conversion rate. Gck is mainly active in liver Not present in brain and muscle, so those organs can not produce their own glucose in the gluconeogenesis pathway d18

glycolysis/gluconeogenesis pathway PW:0000025 Pathway Ontology 22628558 PubMed A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans. Science 2012 Bricker DK Taylor EB Schell JC Orsak T Boutron A Chen YC Cox JE Cardon CM Van Vranken JG Dephoure N Redin C Boudina S Gygi SP Brivet M Thummel CS Rutter J