Glutathione is a major antioxidant in all forms of life and an indicator of cellular oxidative stress. Reduction by the GSR enzyme utilizes NADPH as an electron donor. In a reduced form, glutathione is metabolized in multiple ways leading to the biosynthesis of mercapturonate, glutamate, glycine, cysteine and other amino acids.This pathway was inferred from Homo sapiens pathway [http://www.wikipathways.org/index.php?title=Pathway:WP100&oldid=20893 WP100(r20893)] with a 51% conversion rate.aka gamma-GluAA(Cys) according to PMID:34492635(5-L-Glutamyl)-L-amino acidb5eb5eFormer label: 2.3.2.4 b5eb5eb5eb5eb5e(5-L-Glutamyl)-L-amino acidb5eb5eb5eb5eb5eb5eb5eb5eb5eb5eb5e34492635PubMedGlutathione is an aging-related metabolic signature in the mouse kidney.Aging (Albany NY)2021Ahn ELee JHan JLee SMKwon KSHwang GSglutathione metabolic pathwayPW:0000134Pathway Ontology