The CDP-choline pathway, first identified by Eugene Kennedy in 1956, is the predominant mechanism by which mammalian cells synthesize phosphatidylcholine (PC) for incorporation into membranes or lipid-derived signalling molecules. The CDP-choline pathway represents one half of what is known as the Kennedy pathway. The other half is the CDP-ethanolamine pathway which is responsible for the biosynthesis of the phospholipid product phosphatidylethanolamine (PE).
Source: [https://en.wikipedia.org/wiki/CDP-choline_pathway Wikipedia]
cf2
DAG = aspartate-alanine-glycine
20503434
PubMed
The Kennedy pathway--De novo synthesis of phosphatidylethanolamine and phosphatidylcholine.
IUBMB Life
2010
Gibellini F
Smith TK
phospholipid metabolic pathway
PW:0000155
Pathway Ontology
CDP-choline pathway of phosphatidylcholine biosynthesis
PW:0001336
Pathway Ontology