This pathway describes the parkin-ubiquitin proteasome degradation system. Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP2359) fbe "Caspase-1" originally "Cyclin E" originally "Cullin 1" originally "Parkin" originally "Synphilin 1" originally "Caspase-8" originally "Alpha-synuclein" originally ubiquitin/proteasome degradation pathway PW:0000144 Pathway Ontology 22432004 PubMed Identification of common biological pathways and drug targets across multiple respiratory viruses based on human host gene expression analysis. PLoS One 2012 Smith SB Dampier W Tozeren A Brown JR Magid-Slav M