Latent membrane protein 1 (LMP1) of the Ebstein-Barr Virus (EBV) elicits its oncogenice effects through the activation of several downstream pathways suchs as Pi3K/akt, IRF4, and NFkB pathways. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP262 CPTAC Assay Portal] cf5 d73 ee4 b42 Type your comment here Epstein-Barr virus infection pathway PW:0001057 Pathway Ontology oxidative phosphorylation pathway PW:0001059 Pathway Ontology 16446357 PubMed TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB. J Biol Chem 2006 Uemura N Kajino T Sanjo H Sato S Akira S Matsumoto K Ninomiya-Tsuji J 16477006 PubMed IL-1 receptor-associated kinase 1 is critical for latent membrane protein 1-induced p65/RelA serine 536 phosphorylation and NF-kappaB activation. Proc Natl Acad Sci U S A 2006 Song YJ Jen KY Soni V Kieff E Cahir-McFarland E 18052967 PubMed Expression and regulation of the CC-chemokine ligand 20 during human tuberculosis. Scand J Immunol 2008 Lee JS Lee JY Son JW Oh JH Shin DM Yuk JM Song CH Paik TH Jo EK 18089854 PubMed Hypoxia transcriptionally induces macrophage-inflammatory protein-3alpha/CCL-20 in primary human mononuclear phagocytes through nuclear factor (NF)-kappaB. J Leukoc Biol 2008 Battaglia F Delfino S Merello E Puppo M Piva R Varesio L Bosco MC