Growth factors and miRNA regulating differentiation of hematopoietic stem cells (HSC) to various blood-related cell types. Note that myeloblasts branch off separately from erythrocytes and megakaryocytes. Adapted from an open access image attributed to ZooFari and Mikael Häggström (http://en.wikipedia.org/wiki/User:Mikael_H%C3%A4ggstr%C3%B6m/Gallery#Medical_collaborations) and augmented from literature and NHLBI Progenitor Cell Biology Consortium (PCBC) collaborators. "SCF" originally "SCF" originally f65 "ALK4" originally f65 e8c e8c e8c e8c e8c "CD235a" originally http://www.google.com/patents/CA2862140A1?cl=en Patented derivative of Pyrimido[4,5-b]indole e8c "CD61" originally "SCF" originally "SCF" originally cca 22617791 PubMed MicroRNAs in erythroid and megakaryocytic differentiation and megakaryocyte-erythroid progenitor lineage commitment. Leukemia 2012 Zhang L Sankaran VG Lodish HF 20549139 PubMed The role of micro-ribonucleic acids in normal hematopoiesis and leukemic T-lymphogenesis. Braz J Med Biol Res 2010 20549139 PubMed The role of micro-ribonucleic acids in normal hematopoiesis and leukemic T-lymphogenesis. Braz J Med Biol Res 2010 20549139 PubMed The role of micro-ribonucleic acids in normal hematopoiesis and leukemic T-lymphogenesis. Braz J Med Biol Res 2010 Slavov SN Gimenes Teixeira HL Rego EM hematopoietic stem cell CL:0000037 Cell Type Interleukin mediated signaling pathway PW:0000512 Pathway Ontology basophil CL:0000767 Cell Type erythrocyte CL:0000232 Cell Type peripheral blood stem cell CL:0002246 Cell Type platelet CL:0000233 Cell Type eosinophil CL:0000771 Cell Type neutrophil CL:0000775 Cell Type 24766805 PubMed Reprogramming committed murine blood cells to induced hematopoietic stem cells with defined factors. Cell 2014 24766805 PubMed Reprogramming committed murine blood cells to induced hematopoietic stem cells with defined factors. Cell 2014 Riddell J Gazit R Garrison BS Guo G Saadatpour A Mandal PK Ebina W Volchkov P Yuan GC Orkin SH Rossi DJ common myeloid progenitor CL:0000049 Cell Type monocyte CL:0000576 Cell Type myeloblast CL:0000835 Cell Type megakaryocyte CL:0000556 Cell Type