The Constitutive Androstane Receptor (CAR) is a nuclear receptor and functions as a sensor for xenobiotics. It regulates transcription of genes encoding proteins in metabolism and excretion of xenobiotics. Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP2875). b7a c91 cd2 nuclear receptor subfamily 1, group I, member 3 retinoid X receptor, alpha bdd d52 plays a role in translocation of CAR heat shock protein 90kDa alpha (cytosolic), class A member 1 nuclear receptor subfamily 1, group I, member 3 heat shock protein 90kDa alpha (cytosolic), class A member 1 retinoid X receptor, alpha nuclear receptor subfamily 1, group I, member 3 DnaJ (Hsp40) homolog, subfamily C, member 7 DnaJ (Hsp40) homolog, subfamily C, member 7 nuclear receptor coactivator 6 Sp1 transcription factor nuclear receptor coactivator 1 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha nuclear receptor coactivator 2 structural maintenance of chromosomes 1A cytochrome P450, family 2, subfamily C, polypeptide 9 a2e ATP-binding cassette, sub-family B (MDR/TAP), member 1 eb7 be4 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 b6a cytochrome P450, family 2, subfamily A, polypeptide 6 eb7 b6a cytochrome P450, family 2, subfamily C, polypeptide 19 a2e during fasting ce9 glutathione S-transferase alpha 2 eb7 cytochrome P450, family 3, subfamily A, polypeptide 5 a2e c02 cytochrome P450, family 3, subfamily A, polypeptide 4 a2e eb7 b6a cytochrome P450, family 2, subfamily B, polypeptide 6 a2e ATP-binding cassette, sub-family C (CFTR/MRP), member 3 b6a a7b a7b a7b a7b df0 a9d 20399894 PubMed Bile acids and their nuclear receptor FXR: Relevance for hepatobiliary and gastrointestinal disease. 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