Development of white versus brown adipocytes (figure from Handbook of Obesity). Transcription factors and nuclear regulators controlling the development of white versus brown adipocytes are shown in the pathway.
At the bottom a selection of identified markers of white and brown adipocytes were added (from Nascimento et al). c7df7c"PGC-1α" originally"PGC-1β" originally"Smad8" originally"C/EBPβ" originally"C/EBPδ" originally"Adiponectin" originally"Leptin" originally"C/EBPα" originally"ASC-1" originally"PPARγ" originally"Zfp423" originally"C/EBPβ" originallyc7dc7d25080474PubMedFat cells gain new identities.Sci Transl Med2014Nascimento EBBoon MRvan Marken Lichtenbelt WDregulatory pathwayPW:0000004Pathway Ontologywhite adipocyteCL:0000448Cell Type9781842145562ISBNHandbook of Obesity (3rd edition)CRC Press2014George A. BrayClaude BouchardpreadipocyteCL:0002334Cell Typebrown adipocyteCL:0000449Cell Type