The G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cells and is essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells. Source: [[wikipedia:G12/G13_alpha_subunits|Wikipedia]] This pathway was inferred from Homo sapiens pathway [http://www.wikipathways.org/index.php?title=Pathway:WP524&oldid=21780 WP524(r21780)] with a 89% conversion rate. b9a A41687 S69211 BAA31594 Posh P42338 S33596 G protein mediated signaling pathway via Galpha12/Galpha13 family PW:0000230 Pathway Ontology 12040175 PubMed G protein pathways. Science 2002 Neves SR Ram PT Iyengar R