This pathway describes the Fas induced apoptosis and interplay with Hsp27 in response to stress. More info: [http://www.biocarta.com/pathfiles/h_hsp27Pathway.asp BioCarta]. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP314 CPTAC Assay Portal] ed8 Interim Symbol: Spna1 predicted and Name: spectrin alpha 1 (predicted) receptor (TNFRSF)-interacting serine-threonine kinase 2 Interim Symbol: Arhgdib predicted and Name: Rho, GDP dissociation inhibitor (GDI) beta (predicted) e5b stress response pathway PW:0000237 Pathway Ontology 10914538 PubMed Heat shock proteins--modulators of apoptosis in tumour cells. Leukemia 2000 Creagh EM Sheehan D Cotter TG 18803879 PubMed Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres. BMC Cancer 2008 Ji Q Hao X Meng Y Zhang M Desano J Fan D Xu L FasL mediated signaling pathway PW:0000681 Pathway Ontology