This pathway describes the Fas induced apoptosis and interplay with Hsp27 in response to stress. More info: [BioCarta](http://www.biocarta.com/pathfiles/h_hsp27Pathway.asp). Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP314) ed8 Interim Symbol: Spna1 predicted and Name: spectrin alpha 1 (predicted) receptor (TNFRSF)-interacting serine-threonine kinase 2 Interim Symbol: Arhgdib predicted and Name: Rho, GDP dissociation inhibitor (GDI) beta (predicted) e5b 10914538 PubMed Heat shock proteins--modulators of apoptosis in tumour cells. Leukemia 2000 Creagh EM Sheehan D Cotter TG FasL mediated signaling pathway PW:0000681 Pathway Ontology stress response pathway PW:0000237 Pathway Ontology 18803879 PubMed Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres. BMC Cancer 2008 Ji Q Hao X Meng Y Zhang M Desano J Fan D Xu L