A graphical summary of the molecular signaling events involved in MFAP5-mediated ovarian cancer cell motility and invasiveness. Based on figure 6c in [Leung et al](https://www.ncbi.nlm.nih.gov/pubmed/25277212). Phosphorylation sites were added based on information from PhosphoSitePlus (R), www.phosphosite.org. Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP3301). a0f a2a parentid=Q05397; parentsymbol=FAK; site=PIGNQHIyQPVGKPD; position=tyr861; sitegrpid=447965; ptm=p; direction=u parentid=Q04759; parentsymbol=PRKCQ; site=LGDAktNtFCGtPDy; position=thr538; sitegrpid=447907; ptm=p; direction=u parentid=P19174; parentsymbol=PLCG1; site=EGRNPGFyVEANPMP; position=tyr783; sitegrpid=447667; ptm=p; direction=u parentid=P27361; parentsymbol=MAPK3; site=HtGFLtEyVAtRWyr; position=tyr204; sitegrpid=447543; ptm=p; direction=u parentid=P27361; parentsymbol=MAPK3; site=HDHtGFLtEyVAtRW; position=thr202; sitegrpid=447542; ptm=p; direction=u 25514926 PubMed PhosphoSitePlus, 2014: mutations, PTMs and recalibrations. Nucleic Acids Res 2015 Hornbeck PV Zhang B Murray B Kornhauser JM Latham V Skrzypek E 25277212 PubMed Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential. Nat Commun 2014 Leung CS Yeung TL Yip KP Pradeep S Balasubramanian L Liu J Wong KK Mangala LS Armaiz-Pena GN Lopez-Berestein G Sood AK Birrer MJ Mok SC cancer pathway PW:0000605 Pathway Ontology ovarian cancer DOID:2394 Disease disease pathway PW:0000013 Pathway Ontology disease of cellular proliferation DOID:14566 Disease