Pathway describing the activation of the transcription of the NODAL genes and genes that respond to that. ab5 Transcription factor Smad2 (smad2) sox32: SRY-box containing gene 32, mRNA (cDNA clone MGC:114019 ntl: No tail (ntl), mRNA One-eyed pinhead short form protein (oep) Signaling molecule lefty2 (lft2) (lft2) MAD homolog 2 (Drosophila) (smad2), mRNA (smad2) One-eyed pinhead long form protein (oep) One-eyed pinhead (oep), mRNA (oep) SRY-box containing gene 32, mRNA (cDNA clone MGC:114019 IMAGE:7450460) (sox32) Forkhead box H1 (foxh1), mRNA (foxh1) - forkhead box H1 / schmalspur (sur) Dlx1 (dlx1a) Lefty2 (lft2), mRNA (lft2) MAD homolog 5 (Drosophila), mRNA sox17: SRY-box containing gene 17, mRNA (cDNA clone MGC:91776 Neurogenin (neurog1) Bhikhari (bhik), mRNA (bhik) Neurogenin 1, mRNA (cDNA clone MGC:76812 IMAGE:6963393) (neurog1) Mad-related protein Smad5 (smad5) (smad5) Menin (men1 gene) (men1) Antivin (lft1) Lefty2 (lft2), mRNA (lft2) Homeodomain transcription factor Mixer (mix) (bon) foxg1 / BF1 Fork head domain protein FKD4 / Nodal related 2/ cyclops Neurogenin 1, mRNA (cDNA clone MGC:76812 IMAGE:6963393) (neurog1) Neurogenin 1 (neurog1), mRNA (neurog1) Catalase (cat) flh: Floating head (flh), mRNA Claudin-like gene, clone ZF-A89 (cldnd) - anosmin1 precursor MAD homolog 5 (Drosophila) (smad5), mRNA (smad5) Homeodomain transcription factor Mixer (mix) (bon) Forkhead box H1, mRNA (cDNA clone MGC:55221 IMAGE:2639305) (foxh1) Signaling molecule lefty1 (lft1) (lft1) MAD homolog 2 (Drosophila), mRNA (cDNA clone MGC:113963 IMAGE:7395088) (smad2) ctivin receptor IIb (acvr2b), mRNA (acvr2b) Activin receptor IIA (acvr2a) Smad2 protein (smad2) (smad2) FAST1 (fast1) (foxh1) MAD homolog 5 (Drosophila), mRNA Sox transcription factor 226D7 (sox32) DNA binding factors

18442396 PubMed ERK1 and ERK2 MAPK are key regulators of distinct gene sets in zebrafish embryogenesis. BMC Genomics 2008 Krens SF Corredor-Adamez M He S Snaar-Jagalska BE Spaink HP Nodal signaling pathway PW:0001312 Pathway Ontology