Schematic of predicted interactions of miR-124 with cell cycle and cell differentiation machinery. A genomewide miRNA mimic toxicity screen indicates common and selective vulnerabilities of epithelial ovarian cancer cells. miR-124 is selectively toxic, mainly by inducing terminal cell differentiation via its target SIX4. b9a regulatory pathway PW:0000004 Pathway Ontology 26655797 PubMed A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression. Mol Syst Biol 2015 Shields BB Pecot CV Gao H McMillan E Potts M Nagel C Purinton S Wang Y Ivan C Kim HS Borkowski RJ Khan S Rodriguez-Aguayo C Lopez-Berestein G Lea J Gazdar A Baggerly KA Sood AK White MA