Schematic summarizing predicted miR-517a relationships with ARCN1 and USP1. A genomewide miRNA mimic toxicity screen indicates common and selective vulnerabilities of epithelial ovarian cancer cells. miR-517a targets a common vulnerability, primarily via its target ARCN1. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP3596 CPTAC Assay Portal]. fb3 regulatory pathway PW:0000004 Pathway Ontology 26655797 PubMed A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression. Mol Syst Biol 2015 Shields BB Pecot CV Gao H McMillan E Potts M Nagel C Purinton S Wang Y Ivan C Kim HS Borkowski RJ Khan S Rodriguez-Aguayo C Lopez-Berestein G Lea J Gazdar A Baggerly KA Sood AK White MA