This pathway is based on the [http://www.genome.jp/dbget-bin/show_pathway?map04614+C15850 KEGG pathway] of renin-angiotensin and the [http://www.ambion.com/tools/pathway/pathway.php?pathway=Renin-Angiotensin%20Pathway Ambion pathway] of renin-angiotensincf3a86abdecef83a96dd7a75f32b7cee8fd5e66aabbb0ecbf4aaaba2eacae9caa2a14ac6e97f1ab83b64d48e10d38aabacae9caa2a14ac6e97f1ab83b64d48defbddb96f21ac6cb4cc2dd3de7cf3a86abdecef83a96dd7a75f32b7cfa2af8b6be51e51b7fe91a15cf8f36fa1f65edce10df2d55adadfba5cd47ef1b95cebb05b16d93a76ae0cf7c64aa2b15e61f5fd76d42cf3a86abdecef83a96dd7a75f32b7cc42d69acabdde09f29d93b82a3ff94Assuming this protein stands for TYK2 (it seems TYK1 is not related to this interaction).f16e99e4fc9bCannot find a more specific identifier in this context, see https://en.wikipedia.org/wiki/Serine/threonine-specific_protein_kinase as a start.f2ea85c24c43b1fb4ef5fe22e7faefa77cdcd69e09e65e12e61a2bf8ea46a3efe3a85c57d22d12a1ffa8a86e4aa1acd7d25cecc10d68ed3db3ff1b63a5cb5ccebb05d58f70a35ff9e10a85ae8a33c59b69badbb3b3ef34bbcdf4f77af7b73d40e6addff00afbeabf43e03daff5fee2f0fe22d50d36a71c1fdeff54ea1e60f4af5acfeaf7a86b2beb2b56e21c92b3ac05Mapping based on name of ortholog human gene.b8aa1ffa8a86e4aa1acd7d25cecc10d68de9d35e5cc1ef31fb2eb6fc1a36d8ff16b29f95eebUnclear which ortholog is meant, see also: https://en.wikipedia.org/wiki/Son_of_Sevenlesseffa23Identifier based on similar name for ortholog human generenal hypertensionDOID:1073Human Disease OntologyhypertensionDOID:10763Human Disease Ontologyrenin-angiotensin cascade pathwayPW:0000492Pathway Ontology17898118PubMedAcute angiotensin-converting enzyme inhibition evokes bradykinin-induced sympathetic activation in diabetic rats.Am J Physiol Regul Integr Comp Physiol2007Augustyniak RAMaliszewska-Scislo MChen HFallucca JRossi NF17903697PubMedEffects of aldosterone and angiotensin II receptor blockade on cardiac angiotensinogen and angiotensin-converting enzyme 2 expression in Dahl salt-sensitive hypertensive rats.Am J Hypertens2007Takeda YZhu AYoneda TUsukura MTakata HYamagishi M17785632PubMedRho kinase activation and gene expression related to vascular remodeling in normotensive rats with high angiotensin I converting enzyme levels.Hypertension2007Rivera POcaranza MPLavandero SJalil JE17487824PubMedAssociation of somatic and N-domain angiotensin-converting enzymes from Wistar rat tissue with renal dysfunction in diabetes mellitus.J Renin Angiotensin Aldosterone Syst2007Ronchi FAIrigoyen MCCasarini DE16908757PubMedEnalapril attenuates downregulation of Angiotensin-converting enzyme 2 in the late phase of ventricular dysfunction in myocardial infarcted rat.Hypertension2006Ocaranza MPGodoy IJalil JEVaras MCollantes PPinto MRoman MRamirez CCopaja MDiaz-Araya GCastro PLavandero S7586334PubMedGenetic linkage of the ACE gene to plasma angiotensin-converting enzyme activity but not to blood pressure. 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