Proposed mechanism by which leptin and adiponectin stimulate fatty acid oxidation. Adapted from fig 1 in [Dyck et al.](http://www.ncbi.nlm.nih.gov/pubmed/16497175). Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP3934). This pathway was inferred from Mus musculus pathway "Leptin and adiponectin", WP683 revision 71946, with a 100.0% conversion rate. e92 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:72674 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:105787 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19079 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16846 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:68465 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:107476 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19082 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16847 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12894 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11450 glucose metabolism disease DOID:4194 Disease 16497175 PubMed The role of adipokines as regulators of skeletal muscle fatty acid metabolism and insulin sensitivity. Acta Physiol (Oxf) 2006 Dyck DJ Heigenhauser GJ Bruce CR adiponectin signaling pathway PW:0000563 Pathway Ontology leptin system pathway PW:0000363 Pathway Ontology adiponectin signaling pathway PW:0000563 Pathway Ontology leptin system pathway PW:0000363 Pathway Ontology glucose metabolism disease DOID:4194 Disease