This pathway was created using the GPCRDB (Horn et al., 1998). The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references. ef5 dbf

G protein mediated signaling pathway PW:0000125 Pathway Ontology 11836223 PubMed Classifying G-protein coupled receptors with support vector machines Bioinformatics 2002 Karchin R Karplus K Haussler D 9399852 PubMed GPCRDB: an information system for G protein-coupled receptors Nucleic Acids Research 1998 Horn F Weare J Beukers MW Hörsch S Bairoch A Chen W Edvardsen O Campagne F Vriend G.