Overview of macrophage markers. Macrophages are cells within the tissues that originate from specific white blood cells called monocytes.
Based on [http://www.antibodybeyond.com/reviews/cell-markers/macrophage-marker.htm this list] and tissue-specific gene expression from [http://biogps.org/ GeneAtlas].
Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP4146 CPTAC Assay Portal]This pathway was inferred from Mus musculus pathway [http://wikipathways.org/instance/WP2271_r69962 WP2271 (rev 69962)] with a 90.0% conversion rate.Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12475c38cf7Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12522Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12514efdHomology Mapping from Mus musculus to Homo sapiens: Original ID = L:14066d0cHomology Mapping from Mus musculus to Homo sapiens: Original ID = L:93671b5cd34f4eHomology Mapping from Mus musculus to Homo sapiens: Original ID = L:12524Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16149No homologues found for original id L:23833Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19354Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17105f0bmacrophageCL:0000235Cell Ontology12446022PubMedThe macrophage activity marker sCD14 is increased in patients with multiple sclerosis and upregulated by interferon beta-1b.J Neuroimmunol2002Brettschneider JEcker DBitsch ABahner DBogumil TDressel AElitok EKitze BPoser SWeber FTumani H9286353PubMedCD14 is expressed by subsets of murine dendritic cells and upregulated by lipopolysaccharide.Adv Exp Med Biol1997Mahnke KBecher ERicciardi-Castagnoli PLuger TASchwarz TGrabbe S16888915PubMed[The "classical" macrophage marker CD68 is strongly expressed in primary human fibroblasts].Verh Dtsch Ges Pathol2003Kunz-Schughart LAWeber ARehli MGottfried EBrockhoff GKrause SWAndreesen RKreutz M16132226PubMedIdentification of factor XIII-A as a marker of alternative macrophage activation.Cell Mol Life Sci2005Töröcsik DBárdos HNagy LAdány R15491976PubMedCD163: a specific marker of macrophages in paraffin-embedded tissue samples.Am J Clin Pathol2004Lau SKChu PGWeiss LM12115225PubMedMacrophage subpopulations in rheumatoid synovium: reduced CD163 expression in CD4+ T lymphocyte-rich microenvironments.Arthritis Rheum2002Fonseca JEEdwards JCBlades SGoulding NJ16047947PubMedExpression of CD163 in the liver of patients with viral hepatitis.Pathol Res Pract2005Hiraoka AHoriike NAkbar SMMichitaka KMatsuyama TOnji M9831245PubMedSynergistic effects of colony-stimulating factor 1 and leukemia inhibitory factor in inducing early myeloid cell differentiation.Cell Growth Differ1998Aperlo CSevilla LGuerin SPognonec PBoulukos KE