The PI3K-Akt signaling pathway can be activated by many types of cellular stimuli or toxic insults and regulates many fundamental cellular functions. Activated PI3K phosphorylates AKT, thereby activating it. Once active, Akt controls a number of downstream cellular processes, including apoptosis, protein synthesis, metabolism, and cell cycle, by phosphorylating a range of substrates. Phosphorylation sites were added based on information from PhosphoSitePlus (R), www.phosphosite.org. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP4172 CPTAC Assay Portal] d5b e53 fe7 b84 d06 d67 d49 b56 ee4 a70 b15 ce6 d2a e67 ac1 e78 a61 d07 ed0 c3a SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22084 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16402 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:64930 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18706 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12985 GRB2; growth factor receptor-bound protein 2 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14784 CAV3; caveolin 3 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16453 CAV2; caveolin 2 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16452 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13856 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12827 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12643 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16421 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21960 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12815 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16780 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15962 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14599 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12845 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12843 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:192897 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14268 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21826 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16188 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18708 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12831 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11651 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19699 DOCK1; dedicator of cyto-kinesis Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14083 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:23928 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16185 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15965 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16782 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15975 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16777 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16404 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16420 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16399 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:104099 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16398 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18709 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:94216 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:105083 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18414 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16400 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21923 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12832 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16775 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:241226 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12826 Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000024421 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:226519 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16779 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21828 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12824 CAV1; caveolin 1 caveolae protein 22kD Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16451 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74769 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21827 Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000090210 Homology Mapping from Mus musculus to Homo sapiens: Original ID = M:MGI:96608 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19116 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16197 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16403 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16776 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16194 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16412 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15891 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12834 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22371 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:81877 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16419 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:329278 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20750 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19211 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16773 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12986 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16184 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13857 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12825 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16190 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16772 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20662 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16416 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18707 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:320910 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22370 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21825 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:23797 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12842 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12814 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:75669 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53867 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16186 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15964 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15976 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12829 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11652 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16401 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14600 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:319480 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:320207 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13636 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14164 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14166 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14165 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13637 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13645 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14167 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12977 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11602 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11601 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11600 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22339 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13638 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13639 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13640 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14169 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14168 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14170 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14171 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14172 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14173 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14174 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14175 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14177 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14178 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14179 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14180 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14205 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15234 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16000 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16333 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16334 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17311 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22341 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22340 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18591 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18654 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18590 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18049 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:54635 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56636 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67112 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:71785 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:80857 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:80903 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14183 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16542 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16337 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14184 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16001 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16590 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14182 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13836 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13649 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12978 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14186 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14254 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14257 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18053 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17295 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18595 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18596 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21687 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15967 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15968 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15969 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15970 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15972 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15974 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15977 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16183 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18413 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19109 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:404549 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12669 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14745 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14062 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:243764 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:381810 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53978 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:65086 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67168 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:78134 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14693 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14688 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14696 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14699 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14700 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14701 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14695 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14702 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14704 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14706 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14707 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14708 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14709 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14710 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:64337 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:66066 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:30955 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18176 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16653 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15461 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:105787 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:108079 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56716 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19744 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56717 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74370 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74343 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12539 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15516 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:98432 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21432 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18607 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19053 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19052 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21770 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:225849 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:72930 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:73699 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:235542 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26931 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26932 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:269643 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:51792 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:52432 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:226849 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:59032 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15519 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22027 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:244650 Multiple homologues found: En:ENSG00000214827;En:ENSG00000182712; Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:27379 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:110157 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26396 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26395 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26413 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26417 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56637 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56484 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16150 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12015 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12371 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16151 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12576 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12575 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11909 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12913 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12912 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11911 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:208647 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:208677 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12915 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26427 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:78284 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:231991 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:72508 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:58988 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13685 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:75705 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20104 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13684 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26987 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:218268 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16367 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:320207 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14599 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14599 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14599 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15974 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15974 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15974 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16183 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16183 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16183 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16183 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14702 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12986 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12986 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12986 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12986 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12986 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12986 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16367 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20662 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53867 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53867 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53867 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53867 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16151 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14172 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18654 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18654 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:71785 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13640 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14257 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21687 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21687 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 SOS1; son of sevenless homolog 1 (Drosophila) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747 parentid=P13807; parentsymbol=GYS1; site=PsLsRHssPHQsEDE; position=ser653; sitegrpid=448240; ptm=p; direction=d parentid=P13807; parentsymbol=GYS1; site=RPAsVPPsPsLsRHs; position=ser645; sitegrpid=448238; ptm=p; direction=d parentid=P49815; parentsymbol=TSC2; site=sFRARstsLNERPKs; position=ser939; sitegrpid=448501; ptm=p; direction=d parentid=P49815; parentsymbol=TSC2; site=GLrPrGytISDsAPs; position=thr1462; sitegrpid=448546; ptm=p; direction=d parentid=P31749; parentsymbol=AKT1; site=kDGAtMKtFCGtPEy; position=thr308; sitegrpid=447856; ptm=p; direction=u parentid=P31749; parentsymbol=AKT1; site=tAQMItItPPDQDDs; position=thr450; sitegrpid=447857; ptm=p; direction=u parentid=P31749; parentsymbol=AKT1; site=RPHFPQFsysAsGtA; position=ser473; sitegrpid=447855; ptm=p; direction=u parentid=Q9Y243; parentsymbol=AKT3; site=tDAAtMKtFCGtPEy; position=thr305; sitegrpid=448521; ptm=p; direction=u ea1 parentid=P31751; parentsymbol=AKT2; site=sDGAtMKtFCGtPEy; position=thr309; sitegrpid=448537; ptm=p; direction=u parentid=P49841; parentsymbol=GSK3B; site=SGRPRttsFAEsCkP; position=ser9; sitegrpid=449111; ptm=p; direction=d parentid=O43524; parentsymbol=FOXO3; site=APRRRAVsMDNSNkY; position=ser253; sitegrpid=449108; ptm=p; direction=d parentid=O43524; parentsymbol=FOXO3; site=QsRPRsCtWPLQRPE; position=thr32; sitegrpid=448602; ptm=p; direction=d parentid=O14920; parentsymbol=IKBKB; site=AkELDQGsLCtsFVG; position=ser177; sitegrpid=447492; ptm=p; direction=u parentid=O14920; parentsymbol=IKBKB; site=DQGsLCtsFVGTLQy; position=ser181; sitegrpid=447489; ptm=p; direction=u parentid=Q92934; parentsymbol=BAD; site=PFrGrsRsAPPNLWA; position=ser99; sitegrpid=447862; ptm=p; direction=d parentid=P55211; parentsymbol=CASP9; site=kLRRRFssLHFMVEV; position=ser196; sitegrpid=448454; ptm=p; direction=d parentid=Q00987; parentsymbol=MDM2; site=RkRHksDsIsLsFDE; position=ser188; sitegrpid=453413; ptm=p; direction=u parentid=Q00987; parentsymbol=MDM2; site=RQRkRHksDsIsLsF; position=ser186; sitegrpid=448131; ptm=p; direction=u parentid=Q00987; parentsymbol=MDM2; site=SsRRRAIsEtEENsD; position=ser166; sitegrpid=448130; ptm=p; direction=u parentid=P46527; parentsymbol=CDKN1B; site=GIRkrPAtDDSSTQN; position=thr157; sitegrpid=448645; ptm=p; direction=d parentid=P38936; parentsymbol=CDKN1A; site=GRkRRQtsMTDFyHs; position=ser146; sitegrpid=447836; ptm=p; direction=d parentid=P38936; parentsymbol=CDKN1A; site=QGRkRRQtsMTDFyH; position=thr145; sitegrpid=447837; ptm=p; direction=d parentid=P16220; parentsymbol=CREB1; site=EILsRRPsyRkILND; position=ser119; sitegrpid=448228; ptm=p; direction=u parentid=P23443; parentsymbol=RPS6KB1; site=NQVFLGFtyVAPsVLy; position=thr412; sitegrpid=448607; ptm=p; direction=u parentid=Q13541; parentsymbol=EIF4EBP1; site=GGtLFsttPGGtRII; position=thr46; sitegrpid=447496; ptm=p; direction=d parentid=Q13541; parentsymbol=EIF4EBP1; site=rNsPVtktPPRDLPt; position=thr70; sitegrpid=447528; ptm=p; direction=d parentid=Q13541; parentsymbol=EIF4EBP1; site=FLMECrNsPVtktPP; position=ser65; sitegrpid=447527; ptm=p; direction=d parentid=Q13541; parentsymbol=EIF4EBP1; site=PPGDysttPGGtLFs; position=thr37; sitegrpid=447497; ptm=p; direction=d parentid=P23588; parentsymbol=EIF4B; site=RPRERHPsWRsEEtQ; position=ser406; sitegrpid=470374; ptm=p; direction=u parentid=P62753; parentsymbol=RPS6; site=AKRRRLssLRAstsK; position=ser236; sitegrpid=448093; ptm=p; direction=u parentid=P62753; parentsymbol=RPS6; site=IAKRRRLssLRAsts; position=ser235; sitegrpid=448092; ptm=p; direction=u parentid=P01106; parentsymbol=MYC; site=LLPtPPLsPsRRsGL; position=ser77; sitegrpid=448586; ptm=p; direction=d parentid=P01106; parentsymbol=MYC; site=kkFELLPtPPLsPsR; position=thr73; sitegrpid=448496; ptm=p; direction=d parentid=P38398; parentsymbol=BRCA1; site=LKRKRRPtsGLHPED; position=thr509; sitegrpid=448039; ptm=p; direction=u parentid=P38398; parentsymbol=BRCA1; site=QTSKRHDsDTFPELk; position=ser694; sitegrpid=4787521; ptm=p; direction=u parentid=Q16512; parentsymbol=PKN1; site=MGyGDRtstFCGtPE; position=ser773; sitegrpid=4711320; ptm=p; direction=u parentid=Q16512; parentsymbol=PKN1; site=GyGDRtstFCGtPEF; position=thr774; sitegrpid=447835; ptm=p; direction=u parentid=O00141; parentsymbol=SGK1; site=EHNSTTStFCGTPEY; position=thr256; sitegrpid=448431; ptm=p; direction=u parentid=Q96BR1; parentsymbol=SGK3; site=AIsDTtTtFCGtPEY; position=thr320; sitegrpid=448197; ptm=p; direction=u 21779440 PubMed PTEN Tumor Suppressor Network in PI3K-Akt Pathway Control. 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