Oxidation of a substrate by Cytochrome P450. Adapted from Niesink et al., Chapter 3, p. 47-48. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP43 CPTAC Assay Portal] d05 phase I biotransformation pathway via cytochrome P450 PW:0000375 Pathway Ontology xenobiotics biodegradation pathway PW:0000107 Pathway Ontology hepatocyte CL:0000182 Cell Ontology 9780849392320 ISBN Toxicology; Principles and Applications 1996 Niesink, R.J.M Vries, de, J. Hollinger, M.A.