Protein - protein interaction between genes that are associated with Rett syndrome like phenotype according to the paper Ehrhart et al. 2018 "current developments in the genetics of Rett and Rett-like syndrome" Curr. Psy.
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abd
SIRT1 negatively regulates rRNA expression
Histone Deactylase complex found via Gene Ontology
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c6d
map04722 is ID corresponding to name of PW.
KEGG Pathway Neurotrophin signaling pathway
GABAergic synapse
KEGG Pathway map04727
e2c
GABA B receptor G-protein beta-gamma and Kir3 channel complex
d1a
Alcoholism
KEGG Pathway map05034
Viral carcinogenesis
KEGG Pathway map05203
ad9
cba
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b29
ec4
f42
da7
d83
d5c
d83
GABAergic Synapse
KEGG Pathway map04727
f42
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dce
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f01
c2f
fb9
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f00
Dopaminergic Synapse
KEGG Pathway map04728
Huntington Disease
KEGG Pathway map05016
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c44
Nicotine addiction
KEGG Pathway map05033
fdb
Alcoholism
KEGG Pathway map05034
GABAergic synapse
KEGG Pathway map04727
ed7
bd4
f42
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db1
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acc
Meiotic synapsis pathway
In Caenorhabditis elegans
b87
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d96
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f07
f66
In Saccharomyces Cerevisiae
ee1
f3b
24164323
PubMed
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disease pathway
PW:0000013
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PubMed
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DOID:1206
Disease
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PubMed
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The winged-helix protein brain factor 1 interacts with groucho and hes proteins to repress transcription.
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Stifani S
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The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc.
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Cell Type
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PubMed
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10.1093/jcag/gwy009.249
DOI
A249 Role of LRP6 in KRAS and BRAF mutated colorectal cancer
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A Côté-Biron
J Raisch
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26153216
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Loss-of-function variants in HIVEP2 are a cause of intellectual disability.
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CDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndrome.
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