This pathway is inspired by the Lipidmaps>Sphingolipids pathway [https://lipidmaps.org/pathway/pathways_maps].
Sphingolipids are a class of lipids, which act as signal transduction and cell recognition molecules.
This pathway provides an overview of the different tail lengths (on the right), which are used to convert sphinganine to DH-ceramide. All products are annotated with a lipid-class identifier.
The integrated pathway can be found [https://www.wikipathways.org/index.php/Pathway:WP4690 here].fc1b6caka CoA(16:0)b6cb6cb6cb6cb6cAKA "Coenzyme A, S-docosanoate"AKA "Coenzyme A, S-(tetracosanoate)"AKA "Coenzyme A, S-(15Z)-15-tetracosenoate"AKA "Coenzyme A, S-hexacosanoate"b39sphingolipid biosynthetic pathwayPW:0000162Pathway Ontologysphingomyelin metabolic pathwayPW:0000745Pathway Ontology12011104PubMedDe novo sphingolipid biosynthesis: a necessary, but dangerous, pathway.J Biol Chem2002Merrill AH Jrsphingolipid metabolic pathwayPW:0000197Pathway Ontology11756451PubMedCharacterization of murine sphingosine-1-phosphate phosphohydrolase.J Biol Chem2002Le Stunff HPeterson CThornton RMilstien SMandala SMSpiegel S20923771PubMed20923771PubMedA mouse macrophage lipidome.J Biol Chem2010Dennis EADeems RAHarkewicz RQuehenberger OBrown HAMilne SBMyers DSGlass CKHardiman GReichart DMerrill AH JrSullards MCWang EMurphy RCRaetz CRGarrett TAGuan ZRyan ACRussell DWMcDonald JGThompson BMShaw WASud MZhao YGupta SMaurya MRFahy ESubramaniam S