Ciliary landscape pathway - according to Boldt et al. 2016 - was constructed using the results of affinity proteomics for 217 proteins with known or suspected involvement in ciliary function, resulting in a landscape of 1319 proteins and 4905 interactions of which the most important are shown here (derived from Figure 1). Ciliary function is impaired in a wide spectrum of diseases (ciliopathies) including polycystic kidney disease, Usher syndrome, Bardet-Biedl syndrome, Meckel-Gruber syndrome, and Jeune syndrome. e1c no idea what that should be no annotation found yet no annotation found yet no annotation found yet ciliopathy DOID:0060340 Human Disease Ontology transport pathway PW:0000103 Pathway Ontology 27173435 PubMed An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. Nat Commun 2016 Boldt K van Reeuwijk J Lu Q Koutroumpas K Nguyen TM Texier Y van Beersum SE Horn N Willer JR Mans DA Dougherty G Lamers IJ Coene KL Arts HH Betts MJ Beyer T Bolat E Gloeckner CJ Haidari K Hetterschijt L Iaconis D Jenkins D Klose F Knapp B Latour B Letteboer SJ Marcelis CL Mitic D Morleo M Oud MM Riemersma M Rix S Terhal PA Toedt G van Dam TJ de Vrieze E Wissinger Y Wu KM Apic G Beales PL Blacque OE Gibson TJ Huynen MA Katsanis N Kremer H Omran H van Wijk E Wolfrum U Kepes F Davis EE Franco B Giles RH Ueffing M Russell RB Roepman R