The interplay between immune cells and microRNAs in the tumor microenvironment (TME). MRX34 and MRG‐106 (cobomarsen) are miRNA therapeutic agents.
Adapted from figure 1 in [https://www.ncbi.nlm.nih.gov/pubmed/30578699 Cortez et al].d3bT cellCL:0000084Cell Type30578699PubMedRole of miRNAs in immune responses and immunotherapy in cancer.Genes Chromosomes Cancer2019Cortez MAAnfossi SRamapriyan RMenon HAtalar SCAliru MWelsh JCalin GAmacrophageCL:0000235Cell TypecancerDOID:162Diseaseprofessional antigen presenting cellCL:0000145Cell Typeantigen processing and presentation pathwayPW:0000825Pathway Ontologynatural killer cellCL:0000623Cell Typeneoplastic cellCL:0001063Cell TypelymphocyteCL:0000542Cell Typeimmune response pathwayPW:0000023Pathway Ontologynatural T-regulatory cellCL:0000903Cell Type