Overview of purine metabolism; metabolic markers are highlighted in red, with graphical arrows indicating if a marker is present in higher or lower concentrations compared to normal (healthy) levels.
This pathway was inspired by Chapter 13, edition 5 of the book of Blau (in press). The full version of this PW including disorders, based on ed. 4, can be found [https://www.wikipathways.org/index.php/Pathway:WP4224 here].
Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP4792 CPTAC Assay Portal]c52aka Adenosine deaminase is a nucleoside triphosphate(4−)Adenylosuccinate synthetase isozyme 2succinyladenosine monophosphateribonucleotide reductased0e9783642403378ISBNPhysician's Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases, Chapter 11 and 41ISBN 978-3-642-40337-8 2014Blau, N.Duran, M.Gibson, K.M.Dionisi-Vici, C.purine metabolic pathwayPW:0000031Pathway Ontology10.1016/B978-0-12-405546-9.00005-4DOIChapter 5 Combined Immune Deficiencieshttps://doi.org/10.1016/B978-0-12-405546-9.00005-42014Su, HLenardo, M.