GDNF-RET signalling is at the core of the signalling network in kidney development. These signalling interactions between the metanephric mesenchyme and the nephric duct are crucial to ensure the induction of the ureter from the nephric duct.
This pathway was inferred from Mus musculus pathway [WP4820_109222.gpml] with a 100.0% conversion rate.
c1e
Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:P35546
Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:P97785
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000037211
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000050295
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000025902
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000025932
f46
f55
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000063632
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000004231
f46
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000031665
f46
f27
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000068122
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000046714
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000022144
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000015619
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000046743
Inhibits the complex by binding to RET and blocking complex formation.
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000052516
Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:Q61602
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000021835
Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:Q9D0P8
Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:Q9D6H2
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000018698
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000031558
Homology Mapping from Mus musculus to Homo sapiens: Original ID = S:Q02248
edc
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000074934
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000022144
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000004231
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