This pathway was created using the GPCRDB (Horn et al., 1998), http://www.gpcr.org/7tm/ (originally at http://www.cmbi.kun.nl/7tm/). The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.d72a33G protein mediated signaling pathwayPW:0000125Pathway Ontology9399852PubMedGPCRDB: an information system for G protein-coupled receptors.Nucleic Acids Res1998Horn FWeare JBeukers MWHörsch SBairoch AChen WEdvardsen OCampagne FVriend G11836223PubMedClassifying G-protein coupled receptors with support vector machines.Bioinformatics2002Karchin RKarplus KHaussler D