SARS-CoV-2 Innate immunity evasion mechanisms and cell-specific immune responses; Metabolic overview over ATII cells infection c4e Basigin GM-CSF TIM3 Caspase-8 Binds to 5' PPP RNA region P ba1 c4e a88 c4e c4e bbc f42 c4e bbc bbc c4e c1f c6d e56 Immunoglobulin A (IgA) can bind to the S1 domain of the SARS-CoV-2 spike protein leading to an early burst of IgA that may eliminate the virus in the respiratory mucosa and prevent the development of full adaptive immune response. e5d c4e bbc c4e c6d c4e Immunolobulin M can bind to the RBD of the S1 domain of the SARS-CoV-2, acting as primary immune response. Type your comment here e5d c4e bbc bbc bbc bbc dd1 bbc ec1 bbc c96 c58 bbc a88 c4e c4e ba1 a88 c4e dd1 d77 c71 ba8 bbc bbc The increase of TGFß production induces the IgA isotype switch. e5d bbc c04 bbc High levels of viral load stimulate TGFß production, which is locally secreted. e5d c4e TGF-beta signalling pathway enhanced; Observed in SARS-CoV hypothesises to be conserved in SARS-CoV-2 bbc c4e aed bbc ec1 c4e ba1 c4e ba1 bbc bbc bbc c4e bbc c4e c4e c96 Including MX1, IFTM1, IFIT2 32529952 PubMed SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists. Emerg. Microbes Infect. 2020 Yuen, C. K. Lam, J. Y. Wong, W. M. Mak, L. F. Wang, X. Chu, H. et al. 32353859 PubMed A SARS-CoV-2 protein interaction map reveals targets for drug repurposing Nature 2020 Gordon, D. E. Jang, G. M. Bouhaddou, M. Xu, J. Obernier, K. White, K. M. et al. 32353859 PubMed A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. 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