Glycolysis is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO- and H+. The free energy released in this process is used to form the ATP and NADH.
Gluconeogenesis is a metabolic pathway that results in the generation of glucose from non-carbohydrate carbon substrates such as pyruvate, lactate, glycerol, glucogenic amino acids, and fatty acids.
Description adapted from [http://www.wikipedia.org Wikipedia].
Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP534 CPTAC Assay Portal]Not present in brain and muscle, so those organs can not produce their own glucose in the gluconeogenesis pathwayGlucose-6-Phosphate (2-)Gck is mainly active in liverD-Glucose-6-Phosphate (2-) open formphosphoglucose isomerase (PGI)fructose-6-phosphate (2-) open formglucose-6-phosphate isomeraseefd22628558PubMedA mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans.Science2012Bricker DKTaylor EBSchell JCOrsak TBoutron AChen YCCox JECardon CMVan Vranken JGDephoure NRedin CBoudina SGygi SPBrivet MThummel CSRutter Jglycolysis pathwayPW:0000640Pathway Ontologyglycolysis/gluconeogenesis pathwayPW:0000025Pathway Ontologycitric acid cycle pathwayPW:0000026Pathway Ontologygluconeogenesis pathwayPW:0000641Pathway Ontology