Oxidative phosphorylation is the process in which ATP is formed as a result of the transfer of electrons from NADH or FADH2 to O2 by a series of electron carriers. This process, which takes place in mitochondria, is the major source of ATP in aerobic organisms. [Source](https://www.ncbi.nlm.nih.gov/books/NBK21208/) Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP623) f1c f85 fa1 a9c f60 c4d fe3 ca6 dc8 aac b84 4381909 PubMed Chemi-osmotic theory of oxidative phosphorylation. Nature 1966 Tager JM Veldsema-Currie RD Slater EC 11771674 PubMed Biochemical functions of coenzyme Q10. J Am Coll Nutr 2001 Crane FL 7654171 PubMed Mitochondrial proton conductance and H+/O ratio are independent of electron transport rate in isolated hepatocytes. Biochem J 1995 Porter RK Brand MD 388618 PubMed Keilin's respiratory chain concept and its chemiosmotic consequences. Science 1979 Mitchell P 15490415 PubMed Disturbances of purine nucleotide metabolism in uremia. Semin Nephrol 2004 Rutkowski B Swierczynski J Slominska E Szolkiewicz M Smolenski RT Marlewski M Butto B Rutkowski P 11340051 PubMed Structures and proton-pumping strategies of mitochondrial respiratory enzymes. Annu Rev Biophys Biomol Struct 2001 Schultz BE Chan SI 3881803 PubMed The structure, function and evolution of cytochromes. Prog Biophys Mol Biol 1985 Mathews FS oxidative phosphorylation pathway PW:0001059 Pathway Ontology 15869601 PubMed Lipid rafts are required in Galpha(i) signaling downstream of the P2Y12 receptor during ADP-mediated platelet activation. J Thromb Haemost 2005 Quinton TM Kim S Jin J Kunapuli SP 4291593 PubMed Chemiosmotic hypothesis of oxidative phosphorylation. Nature 1967 Mitchell P Moyle J 14641005 PubMed The molecular machinery of Keilin's respiratory chain. Biochem Soc Trans 2003 Rich PR 10600673 PubMed Crucial role of the membrane potential for ATP synthesis by F(1)F(o) ATP synthases. J Exp Biol 2000 Dimroth P Kaim G Matthey U