We've used the following pathway as a reference: http://www.genome.jp/dbget-bin/show_pathway?rno04115+58918fd6d98fd6fd6cbdcbdp53-dependent G1/S DNA damage checkpoint pathwayPW:0000304Pathway Ontology9918821PubMedProlongation of the p53 response to DNA strand breaks in cells depleted of PARP by antisense RNA expression.Biochem Biophys Res Commun1998Simbulan-Rosenthal CMRosenthal DSDing RBhatia KSmulson ME17000718PubMedp53-independent induction of rat hepatic Mdm2 following administration of phenobarbital and pregnenolone 16alpha-carbonitrile.Toxicol Sci2006Nelson DMBhaskaran VFoster WRLehman-McKeeman LD9565608PubMedPoly(ADP-ribose) binds to specific domains of p53 and alters its DNA binding functions.J Biol Chem1998Malanga MPleschke JMKleczkowska HEAlthaus FR