Biotransformation is the chemical modification (or modifications) made by an organism on a chemical compound. If this modification ends in mineral compounds like CO2, NH4+, or H2O, the biotransformation is called mineralisation.
Biotransformation means chemical alteration of chemicals such as nutrients, amino acids, toxins, and drugs in the body. It is also needed to render non-polar compounds polar so that they are not reabsorbed in renal tubules and are excreted. Biotransformation of xenobiotics can dominate toxicokinetics and the metabolites may reach higher concentrations in organisms than their parent compounds. [https://en.wikipedia.org/wiki/Biotransformation]
Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP702 CPTAC Assay Portal]d32Protein familyphase I biotransformation pathwayPW:0000857Pathway Ontologycellular detoxification pathwayPW:0000124Pathway Ontologyphase I biotransformation pathway via cytochrome P450PW:0000375Pathway Ontology10781873PubMedMolecular and structural aspects of xenobiotic carbonyl metabolizing enzymes. Role of reductases and dehydrogenases in xenobiotic phase I reactions.Toxicology2000Oppermann UCMaser Ephase II biotransformation pathwayPW:0000858Pathway Ontology