This pathway describes the metabolism of tryptophan, an essential amino acid.
Originally converted from rat to human using ortholog information. Edited by Sebastien BurelThis pathway was inferred from Homo sapiens pathway [http://www.wikipathways.org/index.php?title=Pathway:WP465&oldid=30270 WP465(r30270)] with a 57% conversion rate.4-(2-Aminophenyl)-2,4-dioxobutanoateIndolelactate2-Aminomuconate3-Methylindolepyruvate7,8-Dihydro-7,8-dihydroxykynurenateIndole-3-acetateN-MethylserotoninCrotonoyl-CoAN-Methyltryptamine4,8-Dihydroxyquinoline4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoateOxaloacetate3-(2-Aminoethyl)-1H-indol-5-olIndolepyruvateIndole-3-acetaldehydeGlucobrassicin4-Hydroxy-2-quinolinecarboxylicGlutaryl-CoAFormylanthranilate3-Hydroxy-L-kynurenine5-Methoxyindoleacetate2-Aminomuconate(S)-3-Hydroxybutanoyl-CoA5-Hydroxyindoleacetaldehyde3-HydroxyanthranilateIndole-3-acetaldoxime5-Hydroxy-N-formylkynurenineIsophenoxazine5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate6-HydroxyindolelactateAnthranilate5-HydroxykynurenamineAnthranilate5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinate2-Formaminobenzoylacetate4,6-DihydroxyquinolineCinnavalininate5-Hydroxy-L-tryptophan3-Hydroxykynurenamine3-Methoxyanthranilate2-OxoglutarateN-Acetylindoxyl2-Oxoadipate7,8-DihydroxykynurenateXanthurenic5-HydroxyindoleacetateAcetoacetyl-CoA5-(3'-Carboxy-3'-oxopropyl)-4,6-dihydroxypicolinate(Z)-5-Oxohex-2-enedioate5-(2'-Formylethyl)-4,6-dihydroxypicolinateFormyl-N-acetyl-5-methoxykynurenamine8-Methoxykynurenate2-Amino-3-carboxymuconate6-Hydroxykynurenate4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoatepredictedFormylkynurenineAcetyl-CoAL-KynureninepredictedN-AcetylisatinIndole-3-acetamide3-Indoleacetonitrile2-AminophenolpredictedN-Acetylserotonintryptophan metabolic pathwayPW:0000054Pathway Ontology